Any feedback?
Literature summary for 1.1.1.146 extracted from
- The (+)- and (-)-gossypols potently inhibit human and rat 11beta-hydroxysteroid dehydrogenase type 2 (2009), J. Steroid Biochem. Mol. Biol., 113, 177-181.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| corticosterone + NADP+ | Homo sapiens | - |
11-dehydrocorticosterone + NADPH | - |
? |  |
| corticosterone + NADP+ | Rattus norvegicus | - |
11-dehydrocorticosterone + NADPH | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Leydig cell | - |
Rattus norvegicus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| corticosterone + NADP+ | - |
Homo sapiens | 11-dehydrocorticosterone + NADPH | - |
? | |
| corticosterone + NADP+ | - |
Rattus norvegicus | 11-dehydrocorticosterone + NADPH | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
| 11beta-hydroxysteroid dehydrogenase type 1 | - |
Rattus norvegicus |
| 11betaHSD1 | - |
Homo sapiens |
| 11betaHSD1 | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Homo sapiens | |
| NADP+ | - |
Rattus norvegicus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
