Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli and Pichia pastoris | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
V149E | no change in activity compared to wild-type | Homo sapiens |
V149R | no change in activity compared to wild-type | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
membrane | membrane bound enzyme with the catalytic domain localized in the lumen of the ER | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | Homo sapiens | - |
cortisol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD 1 | - |
Homo sapiens |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |