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Literature summary for 1.1.1.145 extracted from

  • Mishra, S.; Chaube, R.
    Distribution and localization of 3beta-hydroxysteroid dehydrogenase (3beta-HSD) in the brain and its regions of the catfish Heteropneustes fossilis (2017), Gen. Comp. Endocrinol., 241, 80-88.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Heteropneustes fossilis
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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Heteropneustes fossilis
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brain significant seasonal and sexual dimorphic changes in the levels of transcript abundance in the whole brain and its regions. In whole brain, level is the highest in post-spawning phase and lowest in spawning phase in males. In females, there is a progressive increase through resting phase to pre-spawning phase, a decline in the spawning phase and increase in the post-spawning phase Heteropneustes fossilis
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cerebellum
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Heteropneustes fossilis
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hypothalamus in females, the level is the highest in the hypothalamus Heteropneustes fossilis
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hypothalamus in males, the highest transcript level is in telencephalon and hypothalamus Heteropneustes fossilis
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medulla oblongata in the preparatory phase, the highest transcript level is seen in medulla oblongata in pituitary in males Heteropneustes fossilis
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olfactory bulb in females, the highest transcript level is in olfactory bulb Heteropneustes fossilis
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olfactory bulb in females, the level is the lowest in olfactory bulb and pituitary Heteropneustes fossilis
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pituitary in the preparatory phase, the lowest transcript level is seen in pituitary in males. In females, the level is the lowest in olfactory bulb and pituitary Heteropneustes fossilis
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pituitary gland in females and males, the lowest transcript level is in pituitary Heteropneustes fossilis
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telencephalon in males, the highest transcript level is in telencephalon and hypothalamus Heteropneustes fossilis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone + NAD+
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Heteropneustes fossilis androst-5-en-3,17-dione + NADH + H+
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?
pregnenolone + NAD+
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Heteropneustes fossilis pregn-5-en-3,20-dione + NADH + H+
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?

Synonyms

Synonyms Comment Organism
3beta-HSD
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Heteropneustes fossilis
3beta-hydroxysteroid dehydrogenase
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Heteropneustes fossilis

Cofactor

Cofactor Comment Organism Structure
NAD+
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Heteropneustes fossilis

Expression

Organism Comment Expression
Heteropneustes fossilis significant seasonal and sexual dimorphic changes in the levels of transcript abundance in the whole brain and its regions additional information