KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
7alpha,27-dihydroxycholesterol | - |
Sus scrofa | |
0.0032 | - |
7alpha-hydroxycholesterol | - |
Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Sus scrofa | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
x * 36000, SDS-PAGE | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + NAD(P)+ | Sus scrofa | - |
pregn-5-en-3,20-dione + NAD(P)H + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0033 | - |
7alpha,25-dihydroxycholesterol as substrate | Sus scrofa |
0.175 | - |
3beta,7alpha-dihydroxy-5-cholestenoic acid as substrate | Sus scrofa |
0.838 | - |
7alpha,27-dihydroxycholesterol as substrate | Sus scrofa |
1.489 | - |
7alpha-hydroxycholesterol as substrate | Sus scrofa |
2.88 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3beta,17alpha-dihydroxy-5-pregnen-20-one + NAD(P)+ | - |
Sus scrofa | 17alpha-hydroxypregn-5-ene-3,20-dione + NAD(P)H | - |
? | |
3beta,7alpha-dihydroxy-5-cholestenoic acid + NAD+ | - |
Sus scrofa | 7alpha-hydroxy-3-oxo-5-cholestenoic acid + NADH | - |
? | |
7alpha,25-dihydroxycholesterol + NAD+ | - |
Sus scrofa | 7alpha,25-dihydroxy-4-cholesten-3-one + NADH | - |
? | |
7alpha,27-dihydroxycholesterol + NAD+ | - |
Sus scrofa | 7alpha,27-dihydroxy-4-cholesten-3-one + NADH | - |
? | |
7alpha-hydroxycholesterol + NAD+ | - |
Sus scrofa | 7alpha-hydroxy-4-cholesten-3-one + NADH | - |
? | |
pregnenolone + NAD(P)+ | - |
Sus scrofa | pregn-5-en-3,20-dione + NAD(P)H + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 36000, SDS-PAGE | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Sus scrofa |