Literature summary for 1.1.1.145 extracted from

Ishii-Ohba, H.; Inano, H.; Bunichi, T.
Testicular and adrenal 3beta-hydroxy-5-ene-steroid dehydrogenase and 5-ene-4-ene isomerase (1987), J. Steroid Biochem., 27, 775-779.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
pregnenolone + NAD(P)+	Rattus norvegicus	-	pregn-5-en-3,20-dione + NAD(P)H + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adrenal gland	-	Rattus norvegicus	-
testis	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3beta,17alpha-dihydroxy-5-pregnen-20-one + NAD(P)+	-	Rattus norvegicus	17alpha-hydroxypregn-5-ene-3,20-dione + NAD(P)H	-	?
pregnenolone + NAD(P)+	-	Rattus norvegicus	pregn-5-en-3,20-dione + NAD(P)H + H+	-	?

Subunits

Subunits	Comment	Organism
?	x * 46500-46800 SDS-PAGE	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Rattus norvegicus
NADP+	-	Rattus norvegicus

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Release 2023.1 (January 2023)