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Literature summary for 1.1.1.102 extracted from

  • Timmins-Schiffman, E.; Roberts, S.
    Characterization of genes involved in ceramide metabolism in the Pacific oyster (Crassostrea gigas) (2012), BMC Res. Notes, 5, 502.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene 3kdsr, DNA and amino acid sequence determination and analysis, sequence comparisons, quantitative expression analysis Crassostrea gigas

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-oxosphinganine + NADPH + H+ Crassostrea gigas
-
dihydrosphingosine + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Crassostrea gigas S4SCP5
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gill
-
Crassostrea gigas
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-oxosphinganine + NADPH + H+
-
Crassostrea gigas dihydrosphingosine + NADP+
-
?

Synonyms

Synonyms Comment Organism
3-ketodihydrosphingosine reductase
-
Crassostrea gigas
3KDSR
-
Crassostrea gigas

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Crassostrea gigas

Expression

Organism Comment Expression
Crassostrea gigas the enzyme is upregulated showing increased expression during the bacterial challenge up

General Information

General Information Comment Organism
physiological function the enzyme is involved in de novo generation of ceramide and in invertebrate stress response Crassostrea gigas