Activating Compound | Comment | Organism | Structure |
---|---|---|---|
EDTA | activation, acyldihydroxyacetone phosphate as substrate | Cavia porcellus | |
EDTA | activation, acyldihydroxyacetone phosphate as substrate | Rattus norvegicus |
General Stability | Organism |
---|---|
freeze-thawing, stable after several cycles | Cavia porcellus |
freeze-thawing, stable after several cycles | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
NADPH | cosubstrate hexadecyldihydroxyacetone phosphate, brain | Rattus norvegicus | |
0.007 | - |
NADPH | cosubstrate palmitoyldihydroxyacetone phosphate, brain | Rattus norvegicus | |
0.01 | - |
NADPH | ascites microsomes | Cavia porcellus | |
0.01 | - |
NADPH | ascites microsomes | Rattus norvegicus | |
0.05 | - |
NADPH | liver mitochondria | Cavia porcellus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | Cavia porcellus | reaction in non-ether lipids biosynthesis | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | Rattus norvegicus | reaction in non-ether lipids biosynthesis | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | Cavia porcellus | reaction in ether lipids biosynthesis | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | Rattus norvegicus | reaction in ether lipids biosynthesis | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Rattus norvegicus | - |
ascites tumor cell | grown in the abdomen of swiss white mice | Cavia porcellus | - |
ascites tumor cell | grown in the abdomen of swiss white mice | Rattus norvegicus | - |
brain | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Cavia porcellus | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Cavia porcellus | - |
spleen | - |
Cavia porcellus | - |
testis | - |
Cavia porcellus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | - |
Cavia porcellus | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | - |
Rattus norvegicus | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | reaction in non-ether lipids biosynthesis | Cavia porcellus | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | reaction in non-ether lipids biosynthesis | Rattus norvegicus | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | - |
Cavia porcellus | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | - |
Rattus norvegicus | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | reaction in ether lipids biosynthesis | Cavia porcellus | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | reaction in ether lipids biosynthesis | Rattus norvegicus | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
hexadecyldihydroxyacetone phosphate + NADPH | - |
Cavia porcellus | 1-hexadecyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
hexadecyldihydroxyacetone phosphate + NADPH | - |
Rattus norvegicus | 1-hexadecyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
palmitoylglycerone phosphate + NADPH | i.e. palmitoyldihydroxyacetone phosphate | Cavia porcellus | 1-palmitoylglycerol 3-phosphate + NADP+ | - |
? | |
palmitoylglycerone phosphate + NADPH | i.e. palmitoyldihydroxyacetone phosphate | Rattus norvegicus | 1-palmitoylglycerol 3-phosphate + NADP+ | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
100 | - |
complete inactivation after 10 min | Cavia porcellus |
100 | - |
complete inactivation after 10 min | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7.5 | broad optimum | Cavia porcellus |
6.5 | 7.5 | broad optimum | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Cavia porcellus | |
NADH | at high concentrations, rat liver | Rattus norvegicus | |
NADPH | specific for NADPH | Cavia porcellus | |
NADPH | specific for NADPH | Rattus norvegicus | |
NADPH | hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates | Cavia porcellus | |
NADPH | hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates | Rattus norvegicus |