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Literature summary for 1.1.1.1 extracted from

  • Esposito, L.; Sica, F.; Raia, C.A.; Giordano, A.; Rossi, M.; Mazzarella, L.; Zagari, A.
    Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution (2002), J. Mol. Biol., 318, 463-477.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli RB791 cells Saccharolobus solfataricus

Crystallization (Commentary)

Crystallization (Comment) Organism
microbatch method in 100 mM Tris-HCl (pH 7.8), 10 mM dithiotreitol with the same volume of 12% (w/v) PEG 4000, 12% (v/v) 2-propanol, 100 mM sodium citrate (pH 5.6) at 20°C Saccharolobus solfataricus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc-containing enzyme Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus P39462
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharolobus solfataricus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethanol + NAD+
-
Saccharolobus solfataricus acetaldehyde + NADH + H+
-
?

Subunits

Subunits Comment Organism
dimer dimer of dimers, X-ray crystallography Saccharolobus solfataricus
homotetramer x-ray crystallography Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
ADH
-
Saccharolobus solfataricus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Saccharolobus solfataricus
NADH
-
Saccharolobus solfataricus