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Literature summary for 1.1.1.1 extracted from

  • Vicenzi, J.T.; Zmijewski, M.J.; Reinhard, M.R.; Landen, B.E.; Muth, W.L.; Marler, P.G.
    Large-scale stereoselective enzymatic ketone reduction with in-situ product removal via polymeric adsorbent resins (1997), Enzyme Microb. Technol., 20, 494-499.
No PubMed abstract available
Search for more literature for 1.1.1.1

Application

Application Comment Organism
synthesis production of (S)-4-(3,4-methylenedioxyphenyl)-2-propanol, which is converted to LY300164, an orally active benzodiazepine Zygosaccharomyces rouxii

Organism

Organism UniProt Comment Textmining
Zygosaccharomyces rouxii
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-methylenedioxyphenyl acetone + NADH
-
 Zygosaccharomyces rouxii (S)-(3,4-methylenedioxyphenyl)-2-propanol + NAD+ + H+
-
 ?

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
33 35
-
 Zygosaccharomyces rouxii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Zygosaccharomyces rouxii

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Zygosaccharomyces rouxii