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Literature summary for 1.1.1.1 extracted from

  • Kragl, U.; Kruse, W.; Hummel, W.; Wandrey, C.
    Enzyme engineering aspects of biocatalysis: Cofactor regeneration as example (1996), Biotechnol. Bioeng., 52, 309-319.
    View publication on PubMed

Application

Application Comment Organism
synthesis production of (S)-1-Phenyl-2-propanol, which is used as an intermediate for the synthesis of amphetamines and as a precursor for anti-hypertensive agents and spasmolytics or anti-epileptics Rhodococcus erythropolis

Organism

Organism UniProt Comment Textmining
Rhodococcus erythropolis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phenyl-2-propanone + NADH + H+
-
Rhodococcus erythropolis (S)-1-phenyl-2-propanol + NAD+
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
-
Rhodococcus erythropolis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.7
-
-
Rhodococcus erythropolis

Cofactor

Cofactor Comment Organism Structure
NADH
-
Rhodococcus erythropolis