Application | Comment | Organism |
---|---|---|
medicine | isozyme ADH2 is a target for anti-amoebic agents | Entamoeba histolytica |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Entamoeba histolytica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclobutyl carbinol | complete inhibition in vitro at 890 nM, anti-amoebic activity on trophozoites by growth inhibition of recombinant Escherichia coli cells | Entamoeba histolytica | |
cyclopropyl carbinol | complete inhibition in vitro at 1820 nM, anti-amoebic activity on trophozoites by growth inhibition of recombinant Escherichia coli cells | Entamoeba histolytica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Entamoeba histolytica | - |
alcohol dehydrogenase 2 | - |
Entamoeba histolytica HM1:1MSS | - |
alcohol dehydrogenase 2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
trophozoite | - |
Entamoeba histolytica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NADH + H+ | - |
Entamoeba histolytica | ethanol + NAD+ | - |
? | |
acetaldehyde + NADH + H+ | - |
Entamoeba histolytica HM1:1MSS | ethanol + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADH2 | - |
Entamoeba histolytica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Entamoeba histolytica |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Entamoeba histolytica |