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IUBMB CommentsA biotinyl-protein. Also carboxylates butanoyl-CoA and catalyses transcarboxylation.
The taxonomic range for the selected organisms is: Bos taurus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
propionyl-coa carboxylase, pccbc, propionyl-coenzyme a carboxylase, acetyl-coa/propionyl-coa carboxylase, pcca-1, pccb-1, pccase, propanoyl-coa:carbon-dioxide ligase (adp-forming),
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Carboxylase, propional coenzyme A (adenosine triphosphate-hydrolyzing)
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Propanoyl-CoA:carbon dioxide ligase
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Propionyl coenzyme A carboxylase
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Propionyl coenzyme A carboxylase (adenosine triphosphate-hydrolyzing)
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Propionyl coenzyme A carboxylase (ATP-hydrolyzing)
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propanoyl-CoA:carbon-dioxide ligase (ADP-forming)
A biotinyl-protein. Also carboxylates butanoyl-CoA and catalyses transcarboxylation.
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ATP + propanoyl-CoA + HCO3-
ADP + phosphate + methylmalonyl-CoA
ATP + propanoyl-CoA + HCO3-
ADP + phosphate + methylmalonyl-CoA
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ATP + propanoyl-CoA + HCO3-
ADP + phosphate + methylmalonyl-CoA
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biotin
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biotin-containing enzyme
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brenda
mid-lactation cow
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brenda
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brenda
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brenda
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brenda
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brenda
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brenda
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PCCB_BOVIN
539
0
58311
Swiss-Prot
Mitochondrion (Reliability: 1)
A0A3Q1N969_BOVIN
752
0
82332
TrEMBL
Mitochondrion (Reliability: 2)
A0A3Q1MM69_BOVIN
740
0
81344
TrEMBL
Mitochondrion (Reliability: 1)
A4FV90_BOVIN
741
0
81718
TrEMBL
Mitochondrion (Reliability: 2)
A0A3Q1LUQ7_BOVIN
734
0
80467
TrEMBL
Mitochondrion (Reliability: 2)
A0A3Q1LTS4_BOVIN
683
0
75270
TrEMBL
Mitochondrion (Reliability: 2)
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58000
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x * 74000, biotin-containing, + x * 58000, SDS-PAGE
64000
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x * 64000 + x * 77000, SDS-PAGE under reducing conditions
74000
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x * 74000, biotin-containing, + x * 58000, SDS-PAGE
77000
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x * 64000 + x * 77000, SDS-PAGE under reducing conditions
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?
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x * 74000, biotin-containing, + x * 58000, SDS-PAGE
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x * 64000 + x * 77000, SDS-PAGE under reducing conditions
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6 - 8.7
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15 min, stable between 6-8, strong denaturation above pH 8.7, liver enzyme
1878
8 - 9.5
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maximal stability, mammary gland enzyme
1878
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0 - 40
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maximal stability
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Lau, E.P.; Cochran, B.C.; Munson, L.; Fall, R.R.
Bovine kidney 3-methylcrotonyl-CoA and propionyl-CoA carboxylase: each enzyme contains nonidentical subunits
Proc. Natl. Acad. Sci. USA
76
214-218
1979
Bos taurus, Sus scrofa
brenda
Garrastazu, C.; Iniesta, M.P.; Aranguez, M.I.; Amil, M.R.
Comparative analysis of propionyl-CoA carboxylase from liver and mammary gland of mid-lactation cow
Comp. Biochem. Physiol. B
99
613-617
1991
Bos taurus
brenda
6.4.1.3 propionyl-CoA carboxylase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
