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Information on EC 6.3.5.2 - GMP synthase (glutamine-hydrolysing) and Organism(s) Pseudomonas aeruginosa

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EC Tree
IUBMB Comments
Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia.
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This record set is specific for:
Pseudomonas aeruginosa
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Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
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Synonyms
glutamine amidotransferase, gmp synthetase, gmp synthase, gatase, guanosine monophosphate synthetase, guanosine 5'-monophosphate synthetase, guanine monophosphate synthetase, xmp aminase, pd0279, gmp synthase (glutamine-hydrolysing), more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Glutamine amidotransferase
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GMP synthase
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GMP synthetase
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GMP synthetase (glutamine hydrolysing)
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GMPS
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Guanosine 5'-monophosphate synthetase
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Guanosine 5-monophosphate synthetase
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Guanosine monophosphate synthetase (glutamine-hydrolyzing)
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Guanylate synthetase
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Guanylate synthetase (glutamine-hydrolyzing)
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Synthetase, guanylate
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Xanthosine 5'-phosphate amidotransferase
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Xanthosine 5-monophosphate aminase
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Xanthosine-5'-phosphate-ammonia ligase
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Xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
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Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
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XMP aminase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amination
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia.
CAS REGISTRY NUMBER
COMMENTARY hide
37318-71-1
not distinguished from EC 6.3.4.1
9023-55-6
EC 6.3.4.1
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G4NPJ3_PSEAI
525
0
57988
TrEMBL
-
A0A8G5A5M2_PSEAI
525
0
57986
TrEMBL
-
A0A8G3P5D0_PSEAI
525
0
57926
TrEMBL
-
A0A8G7AVI8_PSEAI
252
0
27083
TrEMBL
-
A0A8G3FF56_PSEAI
240
0
25923
TrEMBL
-
A0A223PQR1_PSEAI
280
0
30970
TrEMBL
-
A0A8G2QFU5_PSEAI
525
0
57990
TrEMBL
-
A0A223PQQ5_PSEAI
280
0
30938
TrEMBL
-
A0A8G4EM77_PSEAI
269
0
29037
TrEMBL
-
A0A8G6E0Y4_PSEAI
525
0
57958
TrEMBL
-
A0A8G4YTR9_PSEAI
525
0
57974
TrEMBL
-
A0A8G5HBC6_PSEAI
291
0
32557
TrEMBL
-
A0A8G6D1V9_PSEAI
525
0
57907
TrEMBL
-
A0A8G7FH39_PSEAI
525
0
57990
TrEMBL
-
A0A8G7CGQ7_PSEAI
525
0
57933
TrEMBL
-
A0A8G6GSU0_PSEAI
525
0
57940
TrEMBL
-
A0A223PQQ8_PSEAI
280
0
30828
TrEMBL
-
A0A8G5CNQ3_PSEAI
236
0
25564
TrEMBL
-
A0A8G6JZU2_PSEAI
293
0
32728
TrEMBL
-
A0A223PQR9_PSEAI
280
0
30956
TrEMBL
-
A0A8G2VWQ1_PSEAI
525
0
57991
TrEMBL
-
A0A8B5ARQ1_PSEAI
525
0
57988
TrEMBL
-
A0A8G3TFR9_PSEAI
525
0
57992
TrEMBL
-
A0A8G4FM75_PSEAI
525
0
57944
TrEMBL
-
A0A8G4EI06_PSEAI
257
0
29097
TrEMBL
-
B6CVU0_PSEAI
281
0
30627
TrEMBL
-
A0A8G3FMU7_PSEAI
287
0
32257
TrEMBL
-
A0A223PQR2_PSEAI
280
0
30937
TrEMBL
-
A0A8G4SW80_PSEAI
507
0
56063
TrEMBL
-
A0A8G6FLE9_PSEAI
238
0
25720
TrEMBL
-
A0A8G6V196_PSEAI
525
0
57946
TrEMBL
-
A0A8F9JXV5_PSEAI
525
0
57976
TrEMBL
-
A0A0D7MJ82_PSEAI
525
0
57960
TrEMBL
-
A0A8G6WDT4_PSEAI
525
0
57986
TrEMBL
-
A0A8G4AFH1_PSEAI
525
0
57958
TrEMBL
-
A0A8G4UKF4_PSEAI
292
0
32671
TrEMBL
-
A0A2R3ISJ2_PSEAI
525
0
57975
TrEMBL
-
A0A069PZ10_PSEAI
240
0
27414
TrEMBL
-
A0A8G6Y7N0_PSEAI
525
0
57972
TrEMBL
-
A0A8G7AJH0_PSEAI
275
0
31051
TrEMBL
-
A0A8G4AIZ5_PSEAI
525
0
57968
TrEMBL
-
A0A8G5W992_PSEAI
525
0
57972
TrEMBL
-
A0A8G7LL22_PSEAI
525
0
57958
TrEMBL
-
B6CVW8_PSEAI
281
0
30613
TrEMBL
-
A0A8G7AKS4_PSEAI
257
0
29055
TrEMBL
-
A0A6A9K817_PSEAI
525
0
57988
TrEMBL
-
B6CVU5_PSEAI
281
0
30653
TrEMBL
-
B6CVW4_PSEAI
281
0
30681
TrEMBL
-
G8GJP1_PSEAI
313
0
34474
TrEMBL
-
A0A8G4TMG5_PSEAI
223
0
24338
TrEMBL
-
A0A8G4TC46_PSEAI
525
0
57992
TrEMBL
-
A0A8G4UF18_PSEAI
242
0
26109
TrEMBL
-
A0A223PQP5_PSEAI
280
0
30924
TrEMBL
-
A0A3G1HAE8_PSEAI
304
0
33433
TrEMBL
-
A0A8G5H3K9_PSEAI
251
0
26909
TrEMBL
-
A0A8G7AK63_PSEAI
242
0
26139
TrEMBL
-
A0A8G6M4F6_PSEAI
525
0
57958
TrEMBL
-
A0A6H3GFV1_PSEAI
525
0
57907
TrEMBL
-
A0A8G4HGE5_PSEAI
525
0
57972
TrEMBL
-
A0A077JN20_PSEAI
527
0
58162
TrEMBL
-
A0A8G2Z616_PSEAI
525
0
57998
TrEMBL
-
A0A8G2VBJ2_PSEAI
525
0
57946
TrEMBL
-
A0A5E9LPW4_PSEAI
232
0
25979
TrEMBL
-
A0A2R3IXG5_PSEAI
240
0
27416
TrEMBL
-
A0A8G3CNN7_PSEAI
239
0
25820
TrEMBL
-
A0A8G2QVE4_PSEAI
525
0
57986
TrEMBL
-
A0A8F9P9K0_PSEAI
525
0
57932
TrEMBL
-
A0A367MHB6_PSEAI
525
0
57917
TrEMBL
-
A0A223PQQ7_PSEAI
280
0
30886
TrEMBL
-