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Information on EC 6.3.4.4 - adenylosuccinate synthase and Organism(s) Sus scrofa

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EC Tree
     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.4 adenylosuccinate synthase
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Select one or more organisms in this record: ?
This record set is specific for:
Sus scrofa
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Word Map
The taxonomic range for the selected organisms is: Sus scrofa
The enzyme appears in selected viruses and cellular organisms
Synonyms
adenylosuccinate synthetase, adssl1, adss1, adenylosuccinate synthase, pfadss, adss2, ampss, succino-amp synthetase, adenylosuccinate synthetase 1, as-synthetase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Adenylosuccinate synthase
-
-
-
-
Adenylosuccinate synthetase
-
-
-
-
AdSS
-
-
-
-
AMPSase
-
-
-
-
IMP--aspartate ligase
-
-
-
-
IMP-aspartate ligase
-
-
-
-
Succino-AMP synthetase
-
-
-
-
Succinoadenylic kinosynthetase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amination
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
IMP:L-aspartate ligase (GDP-forming)
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CAS REGISTRY NUMBER
COMMENTARY hide
9023-57-8
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
GTP + IMP + L-Asp
GDP + phosphate + adenylosuccinate
show the reaction diagram
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
-
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
-
overview
-
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.23
Asp
-
-
0.011
GTP
-
-
pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.7
calculated from sequence
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
low level
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
ADSS1 is predominantly expressed in the striated muscle tissue, ADSS1 is up-regulated significantly along with muscle growth
Manually annotated by BRENDA team
weak expression level of ADSS2 mRNA
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
high expression level of ADSS2 mRNA
Manually annotated by BRENDA team
additional information
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
PURA1_PIG
457
0
50098
Swiss-Prot
Mitochondrion (Reliability: 5)
PURA2_PIG
456
0
50140
Swiss-Prot
other Location (Reliability: 3)
A0A8D0YX63_PIG
452
0
49714
TrEMBL
Mitochondrion (Reliability: 5)
A0A8D0XJ43_PIG
480
0
52988
TrEMBL
other Location (Reliability: 4)
A0A8D0N300_PIG
480
0
52995
TrEMBL
Mitochondrion (Reliability: 4)
A0A8D0LJI8_PIG
441
0
48652
TrEMBL
other Location (Reliability: 5)
A0A8D0QTH1_PIG
452
0
49684
TrEMBL
other Location (Reliability: 4)
A0A4X1T4K4_PIG
412
0
44992
TrEMBL
other Location (Reliability: 3)
A0A8D0QXB7_PIG
421
0
46400
TrEMBL
other Location (Reliability: 4)
A0A8D0KHX5_PIG
228
0
24386
TrEMBL
other Location (Reliability: 1)
A0A8D1KVK5_PIG
434
0
47717
TrEMBL
other Location (Reliability: 3)
A0A8D0INT3_PIG
456
0
50362
TrEMBL
other Location (Reliability: 3)
A0A8D0LL49_PIG
227
0
23960
TrEMBL
Mitochondrion (Reliability: 4)
A0A8D1X5R4_PIG
372
0
40909
TrEMBL
other Location (Reliability: 3)
A0A8D0WXY7_PIG
415
0
45365
TrEMBL
other Location (Reliability: 3)
A0A8D1DDR1_PIG
403
0
44132
TrEMBL
other Location (Reliability: 2)
A0A8D1TM70_PIG
408
0
44633
TrEMBL
other Location (Reliability: 3)
A0A5G2QUM7_PIG
421
0
46400
TrEMBL
other Location (Reliability: 4)
A0A8D1ZJ11_PIG
421
0
46430
TrEMBL
Mitochondrion (Reliability: 5)
A0A287BAM7_PIG
412
0
44992
TrEMBL
other Location (Reliability: 3)
A0A5G2QKB5_PIG
440
0
48166
TrEMBL
other Location (Reliability: 4)
A0A8D0N4B1_PIG
434
0
47790
TrEMBL
other Location (Reliability: 3)
A0A8D0TZ22_PIG
394
0
43725
TrEMBL
other Location (Reliability: 1)
A0A4X1TTC3_PIG
457
0
50198
TrEMBL
other Location (Reliability: 4)
A0A8D1NBQ9_PIG
452
0
49781
TrEMBL
other Location (Reliability: 3)
A0A8D0TYS9_PIG
457
0
50722
TrEMBL
other Location (Reliability: 5)
A0A8D1CMM7_PIG
434
0
47736
TrEMBL
other Location (Reliability: 3)
A0A8D0IRD7_PIG
453
0
48862
TrEMBL
other Location (Reliability: 4)
A0A8D1UK50_PIG
440
0
48166
TrEMBL
other Location (Reliability: 4)
A0A8D0J0V1_PIG
393
0
43156
TrEMBL
Mitochondrion (Reliability: 3)
A0A8D1NJ23_PIG
389
0
42461
TrEMBL
other Location (Reliability: 3)
A0A8D1FUK5_PIG
452
0
49728
TrEMBL
Mitochondrion (Reliability: 5)
A0A480N391_PIG
548
0
59224
TrEMBL
Mitochondrion (Reliability: 5)
A0A8D1X486_PIG
453
0
50482
TrEMBL
other Location (Reliability: 3)
A0A8D1FLT4_PIG
421
0
46444
TrEMBL
Mitochondrion (Reliability: 5)
A0A8D1KJC6_PIG
440
0
48210
TrEMBL
Mitochondrion (Reliability: 5)
A0A480NVK0_PIG
455
0
50085
TrEMBL
other Location (Reliability: 3)
A0A287BAF3_PIG
452
0
49684
TrEMBL
other Location (Reliability: 4)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stayton, M.M.; Rudolph, F.B.; Fromm, H.J.
Regulation, genetics, and properties of adenylosuccinate synthetase
Curr. Top. Cell. Regul.
22
103-141
1983
Azotobacter vinelandii, Bacillus subtilis, Gallus gallus, Oryctolagus cuniculus, Escherichia coli, Homo sapiens, Leishmania donovani, Rattus norvegicus, Schizosaccharomyces pombe, Sus scrofa, Triticum aestivum, Trypanosoma cruzi
Manually annotated by BRENDA team
Li, X.; Zhu, Z.; Mo, D.; Wang, H.; Yang, S.; Zhao, S.; Li, K.
Comparative molecular characterization of ADSS1 and ADSS2 genes in pig (Sus scrofa)
Comp. Biochem. Physiol. B
147B
271-277
2007
Sus scrofa (A4Z6H0), Sus scrofa (A4Z6H1)
-
Manually annotated by BRENDA team