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Information on EC 6.3.4.15 - biotin-[biotin carboxyl-carrier protein] ligase and Organism(s) Drosophila melanogaster

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EC Tree
IUBMB Comments
The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC 6.3.4.14, biotin carboxylase. The carboxyl group is eventually transferred to acetyl-CoA by EC 2.1.3.15, acetyl-CoA carboxytransferase. In some organisms the carrier protein is part of EC 6.4.1.2, acetyl-CoA carboxylase.
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This record set is specific for:
Drosophila melanogaster
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Word Map
The taxonomic range for the selected organisms is: Drosophila melanogaster
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
biotin ligase, bira protein, biotin-protein ligase, biotin holoenzyme synthetase, bacterial bira biotin ligase, biotin acetyl-coa carboxylase ligase, holocarboxylase synthetase 1, group i biotin protein ligase, biotin:apocarboxylase ligase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acetyl CoA holocarboxylase synthetase
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Acetyl coenzyme A holocarboxylase synthetase
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Biotin holoenzyme synthetase
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Biotin--protein ligase
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Biotin-[acetyl coenzyme A carboxylase] synthetase
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Biotin-[acetyl-CoA carboxylase] synthetase
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Biotin:apocarboxylase ligase
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HCS
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Synthetase, biotin-[acetyl coenzyme A carboxylase]
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amination
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
biotin:apo-[carboxyl-carrier protein] ligase (AMP-forming)
The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC 6.3.4.14, biotin carboxylase. The carboxyl group is eventually transferred to acetyl-CoA by EC 2.1.3.15, acetyl-CoA carboxytransferase. In some organisms the carrier protein is part of EC 6.4.1.2, acetyl-CoA carboxylase.
CAS REGISTRY NUMBER
COMMENTARY hide
37340-95-7
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A0B4LGS6_DROME
999
0
110993
TrEMBL
Mitochondrion (Reliability: 5)
Q9VNC3_DROME
1041
0
115924
TrEMBL
Mitochondrion (Reliability: 5)
A0A0B4KF92_DROME
993
0
110354
TrEMBL
Mitochondrion (Reliability: 5)
A0A0B4LGM5_DROME
1047
0
116564
TrEMBL
Mitochondrion (Reliability: 5)