Reference on EC 6.3.3.3 - dethiobiotin synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bower, S.; Perkins, J.B.; Yocum, R.R.; Howitt, C.L.; Rahaim, P.; Pero, J.
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon
J. Bacteriol.
178
4122-4130
1996
Bacillus subtilis
Izumi, Y.; Kano, Y.; Inagaki, K.; Kawase, N.; Tani, Y.; Yamada, H.
Characterization of biotin biosynthetic enzymes of Bacillus sphaericus: a dethiobiotin producing bacterium
Agric. Biol. Chem.
45
1983-1989
1981
Klebsiella aerogenes, Alcaligenes faecalis, Priestia megaterium, Bacillus roseus, Lysinibacillus sphaericus, Corynebacterium glutamicum, Escherichia coli, Klebsiella pneumoniae, Lipomyces starkeyi, Pseudomonas taetrolens, Rhodotorula glutinis, Saccharomyces kloeckerianus, Sporobolomyces coprophilus, Sporidiobolus salmonicolor
-
Eisenberg, M.A.; Krell, K.
Dethiobiotin synthetase
Methods Enzymol.
62
348-352
1979
Escherichia coli
Izumi, Y.; Tani, Y.; Ogata, K.
Microbiological biosynthesis of biotin
Methods Enzymol.
62
326-338
1979
Pseudomonas graveolens
Yang, H.C.; Tani, Y.; Ogata, K.
Synthesis of biotin vitamers from biotin diaminocarboxylic acid or 7,8-diaminopelargonic acid by a purified enzyme of Pseudomonas graveolens
Agric. Biol. Chem.
34
1748-1750
1970
Pseudomonas graveolens
-
Krell, K.; Eisenberg, M.A.
The purification and properties of dethiobiotin synthetase
J. Biol. Chem.
245
6558-6566
1970
Escherichia coli
Cheeseman, P.; Pai, C.H.
Partial purification and properties of D-desthiobiotin synthetase from Escherichia coli
J. Bacteriol.
104
726-733
1970
Escherichia coli
Alexeev, D.; Bury, S.M.; Boys, C.W.G.; Turner, M.A.; Sawyer, L.; Ramsey, A.J.; Baxter, H.C.; Baxter, R.L.
Sequence and crystallization of Escherichia coli dethiobiotin synthetase, the penultimate enzyme of biotin biosynthesis
J. Mol. Biol.
235
774-776
1994
Escherichia coli
Gibson, K.J.; Lorimer, G.H.; Rendina, A.R.; Taylor, W.S.; Cohen, G.; Gatenby, A.A.; Payne, W.G.; Roe, D.C.; Lockett, B.A.; Nudelman, A.; Marcovici, D.; Nachum, A.; Wexler, B.A.; Marsilii, E.L.; Turner, I.M.; Laurie, D.H.; Kalbach, C.E.; Chi, H.
Dethiobiotin synthetase: the carbonylation of 7,8-diaminononanoic acid proceeds regiospecifically via the N7-carbamate
Biochemistry
34
10976-10984
1995
Escherichia coli
Sakurai, N.; Akatsuka, H.; Kawai, E.; Imai, Y.; Komatsubara, S.
Complete sequence and organization of the Serratia marcescens biotin operon
Microbiology
142
3295-3303
1996
Serratia marcescens
Schneider, G.; Lindqvist, Y.
Structure of ATP-dependent carboxylase, dethiobiotin synthase
Methods Enzymol.
279
376-385
1997
Escherichia coli
Sakurai, N.; Imai, Y.; Masuda, M.; Komatsubara, S.; Tosa, T.
Construction of a biotin-overproducing strain of Serratia marcescens
Appl. Environ. Microbiol.
59
2857-2863
1993
Serratia marcescens
Wu, C.H.; Bao, Y.Y.; Shao, C.P.; Shiuan, D.
Molecular cloning and nucleotide sequencing of bioF (7-keto-8-amino pelargonic acid synthetase), bioC and bioD (dethiobiotin synthetase) genes of Erwinia herbicola
Biochem. Mol. Biol. Int.
41
311-315
1997
Pantoea agglomerans
Alexeev, D.; Baxter, R.L.; Smekal, O.; Sawyer, L.
Substrate binding and carboxylation by dethiobiotin synthetase - a kinetic and X-ray study
Curr. Biol.
3
1207-1215
1995
Escherichia coli
Huang, W.; Lindqvist, Y.; Schneider, G.; Gibson, K.J.; Flint, D.; Lorimer, G.
Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution
Structure
2
407-414
1994
Escherichia coli
Baxter, R.L.; Baxter, H.C.
The mechanism of Escherichia coli dethiobiotin synthetase - a closure of the ureido ring of dethiobiotin involves formation of a carbamic-phosphate mixed anhydride
J. Chem. Soc. Chem. Commun.
1994
759-760
1994
Escherichia coli
-
Baxter, R.L.; Ramsey, A.J.; MxIver, L.A.; Baxter, H.C.
Mechanism of dethiobiotin synthetase - characterization of the 8-aminocarbamate of (7R,8S)-7,8-diaminononanoate as an enzyme-bound intermediate
J. Chem. Soc. Chem. Commun.
1994
559-560
1994
Escherichia coli
-
Yang, G.; Sandalova, T.; Lohman, K.; Lindqvist, Y.; Rendina, A.R.
Active site mutants of the Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties
Biochemistry
36
4751-4760
1997
Escherichia coli
Hatakeyama, K.; Hohama, K.; Vertes, A.A.; Kobayashi, M.; Kurusu, Y.; Yukawa, H.
Genomic organization of the biotin biosynthetic genes of coryneform bacteria: cloning and sequencing of the bioA-bioD genes from Brevibacterium flavum
DNA Seq.
4
177-184
1993
BRENDA: [Brevibacterium] flavum
Textmining: Escherichia coli, Bactridium flavum, Corynebacteriaceae, Bacillus, Corynebacterium glutamicum
Gloeckler, R.; Ohsawa, I.; Speck, D.; Ledoux, C.; Bernard, S.; Zinsius, M.; Velleval, D.; Kisou, T.; Kamogawa, K.; Lemoine, Y.
Cloning and characterization of the Bacillus sphaericus genes controlling the bioconversion of pimelate into dethiobiotin
Gene
87
63-70
1990
Lysinibacillus sphaericus
Huang, W.; Jia, J.; Gibson, K.J.; Taylor, W.S.; Rendina, A.R.; Schneider, G.; Lindqvist, Y.
Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate
Biochemistry
34
10985-10995
1995
BRENDA: Escherichia coli
Textmining: Electron
Sandalova, T.; Schneider, G.; Kack, H.; Lindqvist, Y.
Structure of dethiobiotin synthetase at 0.97 A resolution
Acta Crystallogr. Sect. D
55
610-624
1999
Escherichia coli
-
Kack, H.; Sandmark, J.; Gibson, K.J.; Schneider, G.; Lindqvist, Y.
Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis
Protein Sci.
7
2560-2566
1998
Escherichia coli
Galperin, M.Y.; Grishin, N.V.
The synthetase domains of cobalamin biosynthesis amidotransferases cobB and cobQ belong to a new family of ATP-dependent amidoligases, related to dethiobiotin synthetase
Proteins
41
238-247
2000
Bacteria, Escherichia coli, Archaea
Alexeev, D.; Baxter, R.L.; Campopiano, D.J.; McAlpine, R.S.; McIver, L.; Sawyer, L.
Rational design of an inhibitor of dethiobiotin synthetase; interaction of 6-hydroxypyrimidin-4(3H)-one with the adenine base binding site
Tetrahedron
54
15891-15898
1998
Escherichia coli
-
Muralla, R.; Chen, E.; Sweeney, C.; Gray, J.A.; Dickerman, A.; Nikolau, B.J.; Meinke, D.
A bifunctional locus (BIO3-BIO1) required for biotin biosynthesis in Arabidopsis
Plant Physiol.
146
60-73
2008
BRENDA: Arabidopsis thaliana (B0F481)
Textmining: Arabidopsis, Bacteria, Escherichia coli, insertion sequences, eukaryota
Dey, S.; Lane, J.M.; Lee, R.E.; Rubin, E.J.; Sacchettini, J.C.
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase
Biochemistry
49
6746-6760
2010
BRENDA: Mycobacterium tuberculosis
Textmining: Helicobacter pylori, Escherichia coli, Bacillus subtilis, Bacillus subtilis (P53555), Homo sapiens
Cobessi, D.; Dumas, R.; Pautre, V.; Meinguet, C.; Ferrer, J.L.; Alban, C.
Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis
Plant Cell
24
1608-1625
2012
Arabidopsis, Bacteria, eukaryota, Magnoliopsida, Arabidopsis thaliana (B0F481), Arabidopsis thaliana, plant
Salaemae, W.; Yap, M.Y.; Wegener, K.L.; Booker, G.W.; Wilce, M.C.; Polyak, S.W.
Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase
Tuberculosis
95
259-266
2015
BRENDA: Escherichia coli (P13000), Escherichia coli, Mycobacterium tuberculosis (P9WPQ5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WPQ5)
Textmining: Fungi, Homo sapiens
Thompson, AP; Wegener, KL; Booker, GW; Polyak, SW; Bruning, JB
Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase.
Acta Crystallogr D Struct Biol
74
965-972
2018
Mycobacterium tuberculosis
Schumann, NC; Lee, KJ; Thompson, AP; Salaemae, W; Pederick, JL; Avery, T; Gaiser, BI; Hodgkinson-Bean, J; Booker, GW; Polyak, SW; Bruning, JB; Wegener, KL; Abell, AD
Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS): Toward Next-Generation Antituberculosis Agents.
ACS Chem Biol
2021
Mycobacterium tuberculosis
Prakash, O; Eisenberg, MA
In vitro synthesis and and regulation of the biotin enzymes of Escherichia coli K-12.
J Bacteriol
134
1002-12
1978
Escherichia coli
Phalip, V; Kuhn, I; Lemoine, Y; Jeltsch, JM
Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake.
Gene
232
43-51
1999
Saccharomyces cerevisiae
Magliano, P; Flipphi, M; Sanglard, D; Poirier, Y
Characterization of the Aspergillus nidulans biotin biosynthetic gene cluster and use of the bioDA gene as a new transformation marker.
Fungal Genet Biol
2010
Aspergillus nidulans, Bacteria, Saccharomyces cerevisiae
Alexeev, D; Baxter, RL; Sawyer, L
Mechanistic implications and family relationships from the structure of dethiobiotin synthetase.
Structure
2
1061-72
1994
Electron
Sandalova, T; Schneider, G; Käck, H; Lindqvist, Y
Structure of dethiobiotin synthetase at 0.97 A resolution.
Acta Crystallogr D Biol Crystallogr
55 ( Pt 3)
610-24
1999
Escherichia coli, Areas
Porebski, PJ; Klimecka, M; Chruszcz, M; Nicholls, RA; Murzyn, K; Cuff, ME; Xu, X; Cymborowski, M; Murshudov, GN; Savchenko, A; Edwards, A; Minor, W
Structural characterization of Helicobacter?pylori dethiobiotin synthetase reveals differences between family members.
FEBS J
2012
Bacteria, Fungi, Homo sapiens
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