Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 6.3.2.19 - ubiquitin-protein ligase and Organism(s) Homo sapiens

for references in articles please use BRENDA:EC6.3.2.19
deleted. The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with EC 6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of EC 2.3.2.23 (E2 ubiquitin-conjugating enzyme) and EC 2.3.2.27 (RING-type E3 ubiquitin transferase)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
-
the enzyme is involved in the ubiquitin-proteasome pathway, UPS, where it mediates the ubiquitin transfer from E2, the ubiquitin-conjugating enzyme to the lysine residue(s) of the substrate
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
D3K2X2_HUMAN
51
0
5348
TrEMBL
other Location (Reliability: 3)
D3K2X1_HUMAN
95
0
10532
TrEMBL
other Location (Reliability: 2)
D3JZW5_HUMAN
143
0
15521
TrEMBL
other Location (Reliability: 2)
UBE2N_HUMAN
152
0
17138
Swiss-Prot
other Location (Reliability: 2)
UB2L3_HUMAN
154
0
17862
Swiss-Prot
other Location (Reliability: 2)
UBE2B_HUMAN
152
0
17312
Swiss-Prot
-
UB2G2_HUMAN
165
0
18566
Swiss-Prot
-
UB2D2_HUMAN
147
0
16735
Swiss-Prot
-
UB2D1_HUMAN
147
0
16602
Swiss-Prot
other Location (Reliability: 2)
UB2D3_HUMAN
147
0
16687
Swiss-Prot
-
UBE2C_HUMAN
179
0
19652
Swiss-Prot
other Location (Reliability: 2)
UBE2S_HUMAN
222
0
23845
Swiss-Prot
other Location (Reliability: 2)
UB2R1_HUMAN
236
0
26737
Swiss-Prot
-
UBC_HUMAN
685
0
77039
Swiss-Prot
-
DDB1_HUMAN
1140
0
126968
Swiss-Prot
-
UB2E1_HUMAN
193
0
21404
Swiss-Prot
-
RING2_HUMAN
336
0
37655
Swiss-Prot
-
CBLB_HUMAN
982
0
109450
Swiss-Prot
-
NEDD4_HUMAN
1319
0
149114
Swiss-Prot
-
UBE2K_HUMAN
200
0
22407
Swiss-Prot
other Location (Reliability: 4)
UBC9_HUMAN
158
0
18007
Swiss-Prot
-
UB2Q1_HUMAN
422
0
46127
Swiss-Prot
-
UB2G1_HUMAN
170
0
19509
Swiss-Prot
-
UFC1_HUMAN
167
0
19458
Swiss-Prot
-
BIRC6_HUMAN
4857
0
530269
Swiss-Prot
Chloroplast (Reliability: 2)
FANCL_HUMAN
375
0
42905
Swiss-Prot
-
UB2L6_HUMAN
153
0
17769
Swiss-Prot
other Location (Reliability: 5)
MDM2_HUMAN
491
0
55233
Swiss-Prot
-
UBC12_HUMAN
183
0
20900
Swiss-Prot
-
UB2V1_HUMAN
147
0
16495
Swiss-Prot
-
UBE2W_HUMAN
151
0
17331
Swiss-Prot
-
UB2Q2_HUMAN
375
0
42818
Swiss-Prot
-
RNF38_HUMAN
515
0
57595
Swiss-Prot
-
UBR1_HUMAN
1749
0
200211
Swiss-Prot
-
UB2J2_HUMAN
259
1
28898
Swiss-Prot
-
UBR2_HUMAN
1755
0
200538
Swiss-Prot
-
UB2E2_HUMAN
201
0
22255
Swiss-Prot
-
UBE2Z_HUMAN
354
0
38210
Swiss-Prot
-
ARI1_HUMAN
557
0
64118
Swiss-Prot
-
UBE2H_HUMAN
183
0
20655
Swiss-Prot
-
UBE2U_HUMAN
321
0
37741
Swiss-Prot
-
UHRF2_HUMAN
802
0
89985
Swiss-Prot
-
TRI25_HUMAN
630
0
70973
Swiss-Prot
-
PRKN_HUMAN
465
0
51641
Swiss-Prot
-
LNX2_HUMAN
690
0
76004
Swiss-Prot
-
PDB
SCOP
CATH
UNIPROT
ORGANISM
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Triad1 is induced on differentiation towards monocytes and granulocytes
-