Reference on EC 6.2.1.4 - succinate-CoA ligase (GDP-forming)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Henning, W.D.; Upton, C.; McFadden, G.; Majumdar, R.; Bridger, W.A.
Cloning and sequencing of the cytoplasmic precursor to the alpha subunit of rat liver mitochondrial succinyl-CoA synthetase
Proc. Natl. Acad. Sci. USA
85
1432-1436
1988
Rattus norvegicus
Jenkins, T.M.; Weitzman, P.D.J.
Physiological role of animal succinate thiokinase
FEBS Lett.
230
6-8
1988
Bos taurus, Mus musculus
Jenkins, T.M.; Eisenthal, R.; Weitzman, P.D.J.
Two distinct thiokinases in both bloodstream and procyclic forms of Trypanosoma brucei
Biochem. Biophys. Res. Commun.
151
257-261
1988
Trypanosoma brucei
Nishimura, J.S.; Ybarra J.; Mitchell, T.; Horowitz P.M.
Isolation, amino acid analysis and refolding of subunits of pig heart succinyl-CoA synthetase
Biochem. J.
250
429-434
1988
Sus scrofa
Jenkins, T.M.; Weitzman, P.D.J.
Distinct physiological roles of animal succinate thiokinases: Association of guanine nucleotide-linked succinate thiokinase with ketone body utilization
FEBS Lett.
205
215-218
1986
Rattus norvegicus
Weitzman, P.D.J.; Jenkins, T.; Else, A.J.; Holt, R.A.
Occurrence of two distinct succinate thiokinases in animal tissues
FEBS Lett.
199
57-60
1986
Bos taurus, Rattus norvegicus
Weitzman, P.D.J.; Jaskowska-Hodges, H.
Pattern of nucleotide utilization in bacterial succinate thiokinases
FEBS Lett.
143
237-240
1982
Acinetobacter calcoaceticus, Acinetobacter calcoaceticus subsp. anitratus, Bordetella bronchiseptica, Brevibacterium leucinophagum, Cereibacter sphaeroides, Chromobacterium violaceum, Mima polymorpha, More, Paracoccus denitrificans, Pseudomonas aeruginosa, Pseudomonas fluorescens, Pseudomonas stutzeri, Thermus aquaticus, Xanthomonas hyacinthi
Baccanari, D.P.; Cha, S.
Succinate thiokinase. VI. Multiple interconvertible forms of the enzyme
J. Biol. Chem.
248
15-24
1973
Sus scrofa
Um, H.D.; Klein, C.
Evidence for allosteric regulation of succinyl-CoA synthetase
Biochem. J.
295
821-826
1993
Dictyostelium discoideum
Anschutz, A.L.; Um, H.D.; Siegel, N.R.; Veron, M.; Klein, C.
P36, a Dictyostelium discoideum protein whose phosphorylation is stimulated by GDP, is homologous to the alpha-subunit of succinyl-CoA synthetase
Biochim. Biophys. Acta
1162
40-46
1993
Dictyostelium discoideum
Um H.D.; Klein, C.
Regulatory role of GDP in the phosphoenzyme formation of guanine nucleotide: specific form of succinyl coenzyme A synthetase
J. Protein Chem.
13
177-185
1994
Dictyostelium discoideum, Sus scrofa
Ryan D.G.; Lin, T.; Brownie, E.; Bridger, W.A.; Wolodko, W.T.
Mutually exclusive splicing generates two distinct isoforms of pig heart succinyl-CoA synthetase
J. Biol. Chem.
272
21151-21159
1997
Sus scrofa (O19069), Sus scrofa
Bailey, D.L.; Wolodko, W.T.; Bridger, W.A.
Cloning, characterization, and expression of the beta subunit of pig heart succinyl-CoA synthetase
Plant Sci.
2
1255-1262
1993
Sus scrofa
Birney, M.A.; Klein, C.
Cloning and expression of the alpha subunit of succinyl-CoA synthetase from Dictyostelium discoideum
Arch. Biochem. Biophys.
319
93-101
1995
Dictyostelium discoideum
Kowluru, A.
Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion
Diabetologia
44
89-94
2001
Rattus norvegicus
Johnson, J.D.; Muhonen, W.W.; Lambeth, D.O.
Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit
J. Biol. Chem.
273
27573-27579
1998
Pigeon
Fraser, M.E.; James, M.N.G.; Bridger, W.A.; Wolodko, W.T.
Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase
J. Mol. Biol.
299
1325-1339
2000
Sus scrofa
Lambeth, D.O.; Tews, K.N.; Adkins, S.; Frohlich, D.; Milavetz, B.I.
Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues
J. Biol. Chem.
279
36621-36624
2004
Rattus norvegicus
Joyce, M.A.; Brownie, E.R.; Hayakawa, K.; Fraser, M.E.
Cloning, expression, purification, crystallization and preliminary X-ray analysis of Thermus aquaticus succinyl-CoA synthetase
Acta Crystallogr. Sect. F
63
399-402
2007
Thermus aquaticus
Kibbey, R.G.; Pongratz, R.L.; Romanelli, A.J.; Wollheim, C.B.; Cline, G.W.; Shulman, G.I.
Mitochondrial GTP regulates glucose-stimulated insulin secretion
Cell Metab.
5
253-264
2007
Rattus norvegicus
Fraser, M.E.; Hayakawa, K.; Hume, M.S.; Ryan, D.G.; Brownie, E.R.
Interactions of GTP with the ATP-grasp domain of GTP-specific succinyl-CoA synthetase
J. Biol. Chem.
281
11058-11065
2006
Sus scrofa
Fleige, T.; Pfaff, N.; Gross, U.; Bohne, W.
Localisation of gluconeogenesis and tricarboxylic acid (TCA)-cycle enzymes and first functional analysis of the TCA cycle in Toxoplasma gondii
Int. J. Parasitol.
38
1121-1132
2008
Toxoplasma gondii (Q1KSE5), Toxoplasma gondii
Tsugawa, H.; Suzuki, H.; Nakagawa, I.; Nishizawa, T.; Saito, Y.; Suematsu, M.; Hibi, T.
Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori
Biochem. Biophys. Res. Commun.
376
46-51
2008
Helicobacter pylori
Ostergaard, E.
Disorders caused by deficiency of succinate-CoA ligase
J. Inherit. Metab. Dis.
31
226-229
2008
Homo sapiens, Homo sapiens (P53597), Homo sapiens (Q96I99)
Miller, C.; Wang, L.; Ostergaard, E.; Dan, P.; Saada, A.
The interplay between SUCLA2, SUCLG2, and mitochondrial DNA depletion
Biochim. Biophys. Acta
1812
625-629
2011
Homo sapiens
Schuermann, M.; Wuebbeler, J.H.; Grote, J.; Steinbuechel, A.
Novel reaction of succinyl coenzyme A (succinyl-CoA) synthetase: activation of 3-sulfinopropionate to 3-Sulfinopropionyl-CoA in Advenella mimigardefordensis strain DPN7T during degradation of 3,3-dithiodipropionic acid
J. Bacteriol.
193
3078-3089
2011
Advenella mimigardefordensis (B3TZD8), Advenella mimigardefordensis (B3TZD9), Advenella mimigardefordensis, Advenella mimigardefordensis DPN7T (B3TZD8), Advenella mimigardefordensis DPN7T (B3TZD9)
Joyce, M.A.; Hayakawa, K.; Wolodko, W.T.; Fraser, M.E.
Biochemical and structural characterization of the GTP-preferring succinyl-CoA synthetase from Thermus aquaticus
Acta Crystallogr. Sect. D
68
751-762
2012
Thermus aquaticus
Li, X.; Wu, F.; Beard, D.A.
Identification of the kinetic mechanism of succinyl-CoA synthetase
Biosci. Rep.
33
145-163
2013
Sus scrofa
Luis, P.B.; Ruiter, J.; Ijlst, L.; de Almeida, I.T.; Duran, M.; Wanders, R.J.; Silva, M.F.
Valproyl-CoA inhibits the activity of ATP- and GTP-dependent succinate:CoA ligases
J. Inherit. Metab. Dis.
37
353-357
2013
Homo sapiens
Huang, J.; Fraser, M.
Structural basis for the binding of succinate to succinyl-CoA synthetase
Acta Crystallogr. Sect. D
72
912-921
2016
Sus scrofa (P53590), Sus scrofa
Huang, J.; Malhi, M.; Deneke, J.; Fraser, M.E.
Structure of GTP-specific succinyl-CoA synthetase in complex with CoA
Acta Crystallogr. Sect. F
71
1067-1071
2015
Sus scrofa (P53590), Sus scrofa
Kacso, G.; Ravasz, D.; Doczi, J.; Nemeth, B.; Madgar, O.; Saada, A.; Ilin, P.; Miller, C.; Ostergaard, E.; Iordanov, I.; Adams, D.; Vargedo, Z.; Araki, M.; Araki, K.; Nakahara, M.; Ito, H.; Gal, A.; Molnar, M.J.; Nagy, Z.; Patocs, A.; Adam-Vizi, V.; Chinopoulos, C.
Two transgenic mouse models for beta-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations
Biochem. J.
473
3463-3485
2016
Mus musculus
Vashisht, K.; Verma, S.; Gupta, S.; Lynn, A.M.; Dixit, R.; Mishra, N.; Valecha, N.; Hamblin, K.A.; Maytum, R.; Pandey, K.C.; van der Giezen, M.
Engineering nucleotide specificity of succinyl-CoA synthetase in Blastocystis the emerging role of gatekeeper residues
Biochemistry
56
534-542
2017
Blastocystis hominis, Blastocystis hominis NandII
Dobolyi, A.; Bago, A.G.; Gal, A.; Molnar, M.J.; Palkovits, M.; Adam-Vizi, V.; Chinopoulos, C.
Localization of SUCLA2 and SUCLG2 subunits of succinyl CoA ligase within the cerebral cortex suggests the absence of matrix substrate-level phosphorylation in glial cells of the human brain
J. Bioenerg. Biomembr.
47
33-41
2015
Homo sapiens (Q96I99), Homo sapiens
Luis, P.; Ruiter, J.; IJlst, L.; De Almeida, I.; Duran, M.; Wanders, R.; Silva, M.
Valproyl-CoA inhibits the activity of ATP- and GTP-dependent succinate CoA ligases
J. Inherit. Metab. Dis.
37
353-357
2014
Homo sapiens
Carrozzo, R.; Verrigni, D.; Rasmussen, M.; de Coo, R.; Amartino, H.; Bianchi, M.; Buhas, D.; Mesli, S.; Naess, K.; Born, A.P.; Woldseth, B.; Prontera, P.; Batbayli, M.; Ravn, K.; Joensen, F.; Cordelli, D.M.; Santorelli, F.M.; Tulinius, M.; Darin, N.; Duno, M.; Jouvencel, P.; Burlina, A.; Stangoni, G.; , B.
Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1 phenotype and genotype correlations in 71 patients
J. Inherit. Metab. Dis.
39
243-252
2016
Homo sapiens (P53597), Homo sapiens
Gomes, C.; Palma, N.; Pons, M.J.; Magallon-Tejada, A.; Sandoval, I.; Tinco-Valdez, C.; Gutarra, C.; Del Valle-Mendoza, J.; Ruiz, J.; Matsuoka, M.
Succinyl-CoA synthetase New antigen candidate of Bartonella bacilliformis
PLoS Negl. Trop. Dis.
10
e0004989
2016
Bartonella bacilliformis (A1UQV9), Bartonella bacilliformis
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