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IUBMB CommentsItaconate can act instead of succinate, and ITP instead of GTP.
The taxonomic range for the selected organisms is: Mus musculus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
succinyl-coa synthetase, suclg1, suclg2, succinate-coa ligase, succinate thiokinase, succinyl coa synthetase, succinic thiokinase, succinyl-coa synthase, succinyl coenzyme a synthetase, g-scs,
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Succinate thiokinase
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Succinic thiokinase
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Succinyl CoA synthetase
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Succinyl coenzyme A synthetase
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Succinyl coenzyme A synthetase (GDP-forming)
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Succinyl coenzyme A synthetase (guanosine diphosphate-forming)
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Succinyl-CoA synthetase (GDP-forming)
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Synthetase, succinyl coenzyme A (guanosine diphosphate-forming)
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Acid-thiol ligation
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succinate:CoA ligase (GDP-forming)
Itaconate can act instead of succinate, and ITP instead of GTP.
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GTP + succinate + CoA
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recycling of succinate to succinyl-CoA at the expense of GTP, involvement in heme biosynthesis
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GTP + succinate + CoA
GDP + phosphate + succinyl-CoA
GTP + succinate + CoA
GDP + phosphate + succinyl-CoA
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GTP + succinate + CoA
GDP + phosphate + succinyl-CoA
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GTP + succinate + CoA
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recycling of succinate to succinyl-CoA at the expense of GTP, involvement in heme biosynthesis
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GTP + succinate + CoA
GDP + phosphate + succinyl-CoA
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SUCA_MOUSE
346
0
36155
Swiss-Prot
Mitochondrion (Reliability: 3)
SUCB2_MOUSE
433
0
46840
Swiss-Prot
Mitochondrion (Reliability: 2)
C6EQH3_MOUSE
414
0
44782
TrEMBL
Mitochondrion (Reliability: 3)
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Jenkins, T.M.; Weitzman, P.D.J.
Physiological role of animal succinate thiokinase
FEBS Lett.
230
6-8
1988
Bos taurus, Mus musculus
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Kacso, G.; Ravasz, D.; Doczi, J.; Nemeth, B.; Madgar, O.; Saada, A.; Ilin, P.; Miller, C.; Ostergaard, E.; Iordanov, I.; Adams, D.; Vargedo, Z.; Araki, M.; Araki, K.; Nakahara, M.; Ito, H.; Gal, A.; Molnar, M.J.; Nagy, Z.; Patocs, A.; Adam-Vizi, V.; Chinopoulos, C.
Two transgenic mouse models for beta-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations
Biochem. J.
473
3463-3485
2016
Mus musculus
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6.2.1.4 succinate-CoA ligase (GDP-forming)
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
