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Information on EC 6.2.1.35 - acetate-[acyl-carrier protein] ligase

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EC Tree
     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.35 acetate-[acyl-carrier protein] ligase
IUBMB Comments
This enzyme, from the anaerobic bacterium Malonomonas rubra, is a component of the multienzyme complex EC 7.2.4.4, biotin-dependent malonate decarboxylase. The enzyme uses the energy from hydrolysis of ATP to convert the thiol group of the acyl-carrier-protein-bound 2'-(5-phosphoribosyl)-3'-dephospho-CoA prosthetic group into its acetyl thioester .
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The enzyme appears in viruses and cellular organisms
Synonyms
ACP-SH:acetate ligase, HS-acyl-carrier protein:acetate ligase, S01.274, [acyl-carrier protein]:acetate ligase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + acetate + an [acyl-carrier protein] = AMP + diphosphate + an acetyl-[acyl-carrier protein]
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PATHWAY SOURCE
PATHWAYS
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