Information on EC 5.4.2.6 - beta-Phosphoglucomutase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY
5.4.2.6
-
RECOMMENDED NAME
GeneOntology No.
beta-Phosphoglucomutase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
group transfer
-
-
intramolecular, phosphate group
-
isomerization
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
galactose degradation I (Leloir pathway)
-
maltose degradation
-
Starch and sucrose metabolism
-
trehalose degradation III
-
trehalose degradation IV
-
SYSTEMATIC NAME
IUBMB Comments
beta-D-Glucose 1,6-phosphomutase
No cofactor requirement has been demonstrated.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
beta-PGM
-
-
-
-
Phosphomutase, beta-glucose
-
-
-
-
TM1254
-
putative beta-phosphoglucomutase
CAS REGISTRY NUMBER
COMMENTARY
68651-99-0
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
var. bacillaris
-
-
Manually annotated by BRENDA team
subsp. lactis, strains 19435 and 65.1
-
-
Manually annotated by BRENDA team
subspecies cremoris IFO 3427
-
-
Manually annotated by BRENDA team
strain MSB8
-
-
Manually annotated by BRENDA team
TEMPERATURE RANGE
TEMPERATURE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
25
50
-
25C: about 70% of maximal activity, 50C: about 40% of maximal activity
PDB
SCOP
CATH
ORGANISM
Bacillus subtilis (strain 168)
Clostridium difficile (strain 630)
Escherichia coli (strain K12)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
Lactococcus lactis subsp. lactis (strain IL1403)
pH STABILITY
pH STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
5
9.5
-
30C, 30 min, stable
6
-
-
0C: about 70% loss of activity after 2 days, -20C: about 30% loss of activity after 2 days, -70C: no loss of activity after 2 days
GENERAL STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
after 12 h in 0.02 M imidazole buffer, at pH 7.0, totally inactivated both at 0C and at -20C. Glycylglycine, N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid and phosphate at the same conditions are able to preserve most of the enzyme activity. Cacodylate, ethylmorpholidate, Tris-maleate and glycerophosphate have an intermediate action
-
STORAGE STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
-70C, 0.02 M phosphate buffer, pH 7.0, stable for at least 6 months
-
-80C, partially purified enzyme, stable for at least 3 months
-
APPLICATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
analysis
-
a specific method for the quantitative determination of beta-glucose 1-phosphate