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Information on EC 5.3.1.6 - ribose-5-phosphate isomerase and Organism(s) Arabidopsis thaliana

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EC Tree
IUBMB Comments
Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.
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This record set is specific for:
Arabidopsis thaliana
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
rpi, ribose-5-phosphate isomerase, phosphoriboisomerase, ribose phosphate isomerase, ctrpi, ribosephosphate isomerase b, d-ribose-5-phosphate isomerase, ribosephosphate isomerase a, ribose-5-phosphate isomerase b, ribose 5-phosphate isomerase a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5-Phosphoribose isomerase
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-
-
-
D-Ribose 5-phosphate isomerase
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-
-
-
D-ribose-5-phosphate ketol-isomerase
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-
-
-
D-xylose ketol-isomerase
-
-
-
-
Isomerase, ribose phosphate
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-
-
-
Phosphopentoisomerase
-
-
-
-
Phosphopentose isomerase
-
-
-
-
Phosphoriboisomerase
-
-
-
-
Ribose phosphate isomerase
-
-
-
-
Ribose-5-P isomerase
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-
-
-
Ribosephosphate isomerase A
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-
-
-
Ribosephosphate isomerase B
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
intramolecular oxidoreduction
-
-
-
-
isomerization
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
D-ribose-5-phosphate aldose-ketose-isomerase
Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.
CAS REGISTRY NUMBER
COMMENTARY hide
9023-83-0
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-ribose-5-phosphate
D-ribulose-5-phosphate
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
D-ribose-5-phosphate
D-ribulose-5-phosphate
show the reaction diagram
the cytosolic ribose-5-phosphate isomerase catalyzes the reversible interconversion of ribulose-5-phosphate and ribose-5-phosphate in the non-oxidative phase of the oxidative pentose phosphate pathway
-
-
?
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene RPI2, At2g01290
UniProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
deficiency in a cytosolic ribose-5-phosphate isomerase causes chloroplast dysfunction, late flowering and premature cell death in Arabidopsis thaliana
metabolism
the cytosolic ribose-5-phosphate isomerase catalyzes the reversible interconversion of ribulose-5-phosphate and ribose-5-phosphate in the non-oxidative phase of the oxidative pentose phosphate pathway, which is part of central metabolism
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
RPI3_ARATH
276
0
29306
Swiss-Prot
Chloroplast (Reliability: 3)
RPI4_ARATH
296
0
32163
Swiss-Prot
Chloroplast (Reliability: 2)
RPI1_ARATH
267
0
28332
Swiss-Prot
other Location (Reliability: 3)
RPI2_ARATH
265
0
28516
Swiss-Prot
other Location (Reliability: 3)
A0A178UMQ6_ARATH
247
0
27014
TrEMBL
Chloroplast (Reliability: 2)
A0A654EQY2_ARATH
265
0
28578
TrEMBL
other Location (Reliability: 3)
A0A178UKQ5_ARATH
201
0
21948
TrEMBL
Chloroplast (Reliability: 2)
A0A178V804_ARATH
276
0
29306
TrEMBL
Chloroplast (Reliability: 3)
A0A5S9X928_ARATH
276
0
29319
TrEMBL
Chloroplast (Reliability: 3)
A0A178W9W1_ARATH
267
0
28332
TrEMBL
other Location (Reliability: 3)
A0A654G8U7_ARATH
326
0
35682
TrEMBL
Chloroplast (Reliability: 2)
A0A1P8BDP5_ARATH
326
0
35682
TrEMBL
Chloroplast (Reliability: 2)
A0A178W072_ARATH
265
0
28530
TrEMBL
other Location (Reliability: 3)
A0A7G2FDF6_ARATH
296
0
32163
TrEMBL
Chloroplast (Reliability: 2)
A0A7G2E3T7_ARATH
913
5
100274
TrEMBL
other Location (Reliability: 2)
A0A654EPN4_ARATH
267
0
28146
TrEMBL
other Location (Reliability: 3)
A0A5S9WRI4_ARATH
267
0
28232
TrEMBL
other Location (Reliability: 3)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
construction of T-DNA knockout mutants of the RPI2 gene, which encodes the cytosolic ribose-5-phosphate isomerase. Knockout of the RPI2 gene does not significantly change the total RPI activity in the mutant plants, but knockout of RPI2 interferes with chloroplast structure and decreases chloroplast photosynthetic capacity. Rpi2 mutants accumulate less starch in the leaves and flower significantly later than wild-type when grown under short-day conditions, and rpi2 mutants display premature cell death in the leaves when grown at an above-normal temperature of 26°C, phenotypes, detailed overview
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene RPI2, phylogenetic analysis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xiong, Y.; DeFraia, C.; Williams, D.; Zhang, X.; Mou, Z.
Deficiency in a cytosolic ribose-5-phosphate isomerase causes chloroplast dysfunction, late flowering and premature cell death in Arabidopsis
Physiol. Plant.
137
249-263
2009
Arabidopsis thaliana (Q9ZU38)
Manually annotated by BRENDA team