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Information on EC 4.2.3.5 - chorismate synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.5 chorismate synthase
IUBMB Comments
Requires FMN. The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH(.)). Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
chorismate synthase, chorismate synthetase, vlaro2, 5-enolpyruvylshikimate-3-phosphate phospholyase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
show the reaction diagram
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