Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 4.2.1.117 - 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)

for references in articles please use BRENDA:EC4.2.1.117
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
IUBMB Comments
Catalyses the dehydration of (2S,3S)-2-methylcitrate, forming the trans isomer of 2-methyl-aconitate (unlike EC 4.2.1.79, which forms only the cis isomer). Part of a propionate degradation pathway. The enzyme from Shewanella oneidensis can also accept citrate and cis-aconitate, but activity with (2S,3S)-2-methylcitrate was approximately 2.5-fold higher. 2-methylisocitrate and isocitrate were not substrates . An iron-sulfur protein.
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
The expected taxonomic range for this enzyme is: Shewanella oneidensis
Synonyms
AcnD, SO_0343, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2S,3S)-2-methylcitrate = 2-methyl-trans-aconitate + H2O
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
Select items on the left to see more content.