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Reference on EC 4.1.2.8 - indole-3-glycerol-phosphate lyase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hyde, C.C.; Ahmed, S.A.; Padlan, E.A.; Miles, E.W.; Davies, D.R.
Three-dimensional structure of the tryptophan synthase alpha2beta2 multienzyme complex from Salmonella typhimurium
J. Biol. Chem.
263
17857-17871
1988
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Ahmed, S.A.; Hyde, C.C.; Thomas, G.; Miles, E.W.
Microcrystals of tryptophan synthase alpha2beta2 complex from Salmonella typhimurium are catalytically active
Biochemistry
26
5492-5498
1987
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Radwanski, E.R.; Barczak, A.J.; Last, R.L.
Characterization of tryptophan synthase alpha subunit mutants of Arabidopsis thaliana
Mol. Gen. Genet.
253
353-361
1996
Arabidopsis thaliana
Automatic Mining of ENzyme DAta
Peracchi, A.; Mozzarelli, A.; Rosi, G.L.
Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha2beta2 complex
Biochemistry
34
9459-9465
1995
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Yang, X.J.; Ruvinov, S.B.; Miles, E.W.
Overexpression and purification of separate tryptophan synthase alpha and beta subunits from Salmonella typhimurium
Protein Expr. Purif.
3
347-354
1992
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Zhao, J.; Last, R.L.
Immunological characterization and chloroplast localization of the tryptophan biosynthetic enzymes of the flowering plant Arabidopsis thaliana
J. Biol. Chem.
270
6081-6087
1995
Arabidopsis thaliana, plant
Automatic Mining of ENzyme DAta
Kulik, V.; Hartmann, E.; Weyand, M.; Frey, M.; Gierl, A.; Niks, D.; Dunn, M.F.; Schlichting, I.
On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes
J. Mol. Biol.
352
608-620
2005
Zea mays (P42390)
Manually annotated by BRENDA team
Yanofsky, C.
The enzymatic conversion of anthranilic acid to indole
J. Biol. Chem.
223
171-184
1956
Escherichia coli
Manually annotated by BRENDA team
Frey, M.; Spiteller, D.; Boland, W.; Gierl, A.
Transcriptional activation of Igl, the gene for indole formation in Zea mays: a structure-activity study with elicitor-active N-acyl glutamines from insects
Phytochemistry
65
1047-1055
2004
Zea mays
Manually annotated by BRENDA team
Farag, M.A.; Fokar, M.; Abd, H.; Zhang, H.; Allen, R.D.; Pare, P.W.
(Z)-3-Hexenol induces defense genes and downstream metabolites in maize
Planta
220
900-909
2005
Zea mays
Manually annotated by BRENDA team
Melanson, D.; Chilton, M.D.; Masters-Moore, D.; Chilton, W.S.
A deletion in an indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize
Proc. Natl. Acad. Sci. USA
94
13345-13350
1997
Zea mays (P42390), Zea mays
Manually annotated by BRENDA team
Frey, M.; Stettner, C.; Pare, P.W.; Schmelz, E.A.; Tumlinson, J.H.; Gierl, A.
An herbivore elicitor activates the gene for indole emission in maize
Proc. Natl. Acad. Sci. USA
97
14801-14806
2000
Zea mays (Q9FQ77), Zea mays
Manually annotated by BRENDA team
Frey, M.; Chomet, P.; Glawischnig, E.; Stettner, C.; Grun, S.; Winklmair, A.; Eisenreich, W.; Bacher, A.; Meeley, R.B.; Briggs, S.P.; Simcox, K.; Gierl, A.
Analysis of a chemical plant defense mechanism in grasses
Science
277
696-699
1997
Zea mays
Manually annotated by BRENDA team
Kriechbaumer, V.; Weigang, L.; Fiesselmann, A.; Letzel, T.; Frey, M.; Gierl, A.; Glawischnig, E.
Characterisation of the tryptophan synthase alpha subunit in maize
BMC Plant Biol.
8
44
2008
Zea mays (B2Y0K4), Zea mays
Manually annotated by BRENDA team
Barends, T.R.; Domratcheva, T.; Kulik, V.; Blumenstein, L.; Niks, D.; Dunn, M.F.; Schlichting, I.
Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate
ChemBioChem
9
1024-1028
2008
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Barends, T.R.; Dunn, M.F.; Schlichting, I.
Tryptophan synthase, an allosteric molecular factory
Curr. Opin. Chem. Biol.
12
593-600
2008
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Zhang, R.; Wang, B.; Ouyang, J.; Li, J.; Wang, Y.
Arabidopsis indole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis
J. Integr. Plant Biol.
50
1070-1077
2008
BRENDA: Arabidopsis thaliana (O22765)
Textmining: Arabidopsis
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Salvini, M.; Boccardi, T.M.; Sani, E.; Bernardi, R.; Tozzi, S.; Pugliesi, C.; Durante, M.
Alpha-tryptophan synthase of Isatis tinctoria: gene cloning and expression
Plant Physiol. Biochem.
46
715-723
2008
Arabidopsis thaliana, Zea mays
Automatic Mining of ENzyme DAta
Dunn, M.F.; Niks, D.; Ngo, H.; Barends, T.R.; Schlichting, I.
Tryptophan synthase: the workings of a channeling nanomachine
Trends Biochem. Sci.
33
254-264
2008
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Mozzarelli, A.; Peracchi, A.; Rossi, G.; Ahmed, S.; Miles, E.
Microspectrophotometric studies on single crystals of the tryptophan synthase alpha 2 beta 2 complex demonstrate formation of enzyme-substrate intermediates
J. Biol. Chem.
264
15774-15780
1989
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Zhuang, X.; Fiesselmann, A.; Zhao, N.; Chen, H.; Frey, M.; Chen, F.
Biosynthesis and emission of insect herbivory-induced volatile indole in rice
Phytochemistry
73
15-22
2012
BRENDA: Oryza sativa (Q7Y1I9), Oryza sativa
Textmining: Zea mays
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Ahmad, S.; Veyrat, N.; Gordon-Weeks, R.; Zhang, Y.; Martin, J.; Smart, L.; Glauser, G.; Erb, M.; Flors, V.; Frey, M.; Ton, J.
Benzoxazinoid metabolites regulate innate immunity against aphids and fungi in maize
Plant Physiol.
157
317-327
2011
Zea mays
Manually annotated by BRENDA team
Jin, Z.; Kim, J.H.; Park, S.U.; Kim, S.U.
Cloning and characterization of indole synthase (INS) and a putative tryptophan synthase alpha-subunit (TSA) genes from Polygonum tinctorium
Plant Cell Rep.
35
2449-2459
2016
BRENDA: Persicaria tinctoria (A0A1C9CXC5), Persicaria tinctoria
Textmining: Escherichia coli, plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Richter, A; Powell, AF; Mirzaei, M; Wang, LJ; Movahed, N; Miller, JK; Pieros, MA; Jander, G
Indole-3-glycerolphosphate synthase, a branchpoint for the biosynthesis of tryptophan, indole, and benzoxazinoids in maize.
Plant J
106
245-257
2021
Zea mays
Automatic Mining of ENzyme DAta
Swift, S; Kuhn, J; Stewart, GS
Selection and analysis of non-interactive mutants in the Escherichia coli tryptophan synthase alpha subunit.
Mol Gen Genet
233
129-35
1992
Escherichia coli
Automatic Mining of ENzyme DAta
Lim, WK; Brouillette, C; Hardman, JK
Thermal stabilities of mutant Escherichia coli tryptophan synthase alpha subunits.
Arch Biochem Biophys
292
34-41
1992
Escherichia coli
Automatic Mining of ENzyme DAta
Kanzaki, H; McPhie, P; Miles, EW
Effect of single amino acid substitutions at positions 49 and 60 on the thermal unfolding of the tryptophan synthase alpha subunit from Salmonella typhimurium.
Arch Biochem Biophys
284
174-80
1991
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Lim, WK; Shin, HJ; Milton, DL; Hardman, JK
Relative activities and stabilities of mutant Escherichia coli tryptophan synthase alpha subunits.
J Bacteriol
173
1886-93
1991
Escherichia coli
Automatic Mining of ENzyme DAta
Ahmed, SA; Miles, EW; Davies, DR
Crystallization and preliminary X-ray crystallographic data of the tryptophan synthase alpha 2 beta 2 complex from Salmonella typhimurium.
J Biol Chem
260
3716-8
1985
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Murphy, TM; Mills, SE
Immunochemical and enzymatic comparisons of the tryptophan synthase alpha subunits from five species of Enterobacteriaceae.
J Bacteriol
97
1310-20
1969
Enterobacteriaceae
Automatic Mining of ENzyme DAta
Napier, ML; Hardman, JK
5-Azidoindole binding to the Escherichia coli tryptophan synthase alpha 2 beta 2 complex.
Arch Biochem Biophys
234
206-13
1984
Escherichia coli
Automatic Mining of ENzyme DAta
Radwanski, ER; Zhao, J; Last, RL
Arabidopsis thaliana tryptophan synthase alpha: gene cloning, expression, and subunit interaction.
Mol Gen Genet
248
657-67
1995
Arabidopsis thaliana
Automatic Mining of ENzyme DAta
Kramer, VC; Koziel, MG
Structure of a maize tryptophan synthase alpha subunit gene with pith enhanced expression.
Plant Mol Biol
27
1183-8
1995
Zea mays, Escherichia coli
Automatic Mining of ENzyme DAta
Ahmed, SA; Miles, EW
Aliphatic alcohols stabilize an alternative conformation of the tryptophan synthase alpha 2 beta 2 complex from Salmonella typhimurium.
J Biol Chem
269
16486-92
1994
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Payne, RC; Nichols, BP; Hecht, SM
Escherichia coli tryptophan synthase: synthesis of catalytically competent alpha subunit in a cell-free system containing preacylated tRNAs.
Biochemistry
26
3197-205
1987
Escherichia coli, Serratia marcescens
Automatic Mining of ENzyme DAta
Tanaka, H; Tanizawa, K; Arai, T; Saito, K; Arai, T; Soda, K
Production of a novel tryptophan analog, beta-1-indazole-L-alanine with tryptophan synthase of Escherichia coli.
FEBS Lett
196
357-60
1986
Escherichia coli
Automatic Mining of ENzyme DAta
Yang, L; Ahmed, SA; Miles, EW
PCR mutagenesis and overexpression of tryptophan synthase from Salmonella typhimurium: on the roles of beta2 subunit Lys-382.
Protein Expr Purif
8
126-36
1996
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Zalkin, H; Yanofsky, C
Yeast gene TRP5: structure, function, regulation.
J Biol Chem
257
1491-500
1982
Saccharomyces cerevisiae, Escherichia coli
Automatic Mining of ENzyme DAta
Warzecha, H; Frank, A; Peer, M; Gillam, EM; Guengerich, FP; Unger, M
Formation of the indigo precursor indican in genetically engineered tobacco plants and cell cultures.
Plant Biotechnol J
5
185-91
2007
Nicotiana tabacum, Indigofera, Zea mays
Automatic Mining of ENzyme DAta
Wang, B; Chu, J; Yu, T; Xu, Q; Sun, X; Yuan, J; Xiong, G; Wang, G; Wang, Y; Li, J
Tryptophan-independent auxin biosynthesis contributes to early embryogenesis in Arabidopsis.
Proc Natl Acad Sci U S A
112
4821-6
2015
Arabidopsis
Automatic Mining of ENzyme DAta
Ribeiro, CL; Silva, CM; Drost, DR; Novaes, E; Novaes, CR; Dervinis, C; Kirst, M
Integration of genetic, genomic and transcriptomic information identifies putative regulators of adventitious root formation in Populus.
BMC Plant Biol
16
66
2016
Arabidopsis
Automatic Mining of ENzyme DAta
Dudek, B; Warskulat, AC; Vogel, H; Wielsch, N; Menezes, RC; Hupfer, Y; Paetz, C; Gebauer-Jung, S; Svato, A; Schneider, B
An Integrated-Omics/Chemistry Approach Unravels Enzymatic and Spontaneous Steps to Form Flavoalkaloidal Nudicaulin Pigments in Flowers of Papaver nudicaule L.
Int J Mol Sci
22
2021
plant
Automatic Mining of ENzyme DAta
Kayastha, AM; Sawa, Y; Nagata, S; Kanzaki, H; Miles, EW
Circular dichroism studies of the coenzyme environment in the active sites of mutant forms of the beta-subunit in the tryptophan synthase alpha 2 beta 2 complex.
Indian J Biochem Biophys
28
352-7
0
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Ahmed, SA; Ruvinov, SB; Kayastha, AM; Miles, EW
Mechanism of mutual activation of the tryptophan synthase alpha and beta subunits. Analysis of the reaction specificity and substrate-induced inactivation of active site and tunnel mutants of the beta subunit.
J Biol Chem
266
21548-57
1991
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Ogasahara, K; Yutani, K
Unfolding-refolding kinetics of the tryptophan synthase alpha subunit by CD and fluorescence measurements.
J Mol Biol
236
1227-40
1994
Escherichia coli
Automatic Mining of ENzyme DAta
Yang, XJ; Miles, EW
A novel intersubunit repair mechanism in the tryptophan synthase alpha 2 beta 2 complex. Critical role of the beta subunit lysine 167 in intersubunit communication.
J Biol Chem
268
22269-72
1993
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Ogasahara, K; Matsushita, E; Yutani, K
Further examination of the intermediate state in the denaturation of the tryptophan synthase alpha subunit. Evidence that the equilibrium denaturation intermediate is a molten globule.
J Mol Biol
234
1197-206
1993
Escherichia coli
Automatic Mining of ENzyme DAta
Ogasahara, K; Yutani, K
Equilibrium and kinetic analyses of unfolding and refolding for the conserved proline mutants of tryptophan synthase alpha subunit.
Biochemistry
36
932-40
1997
Escherichia coli
Automatic Mining of ENzyme DAta
Darawshe, S; Millar, DB; Ahmed, SA; Miles, EW; Minton, AP
Dissociation equilibria of the tryptophan synthase alpha 2 beta 2 complex in saline buffer and guanidine isothiocyanate, as studied by sedimentation equilibrium.
Biophys Chem
69
53-62
1997
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Strambini, GB; Cioni, P; Peracchi, A; Mozzarelli, A
Conformational changes and subunit communication in tryptophan synthase: effect of substrates and substrate analogs.
Biochemistry
31
7535-42
1992
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Peracchi, A; Bettati, S; Mozzarelli, A; Rossi, GL; Miles, EW; Dunn, MF
Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates.
Biochemistry
35
1872-80
1996
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Hur, O; Leja, C; Dunn, MF
Evidence of a low-barrier hydrogen bond in the tryptophan synthase catalytic mechanism.
Biochemistry
35
7378-86
1996
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Vaccari, S; Benci, S; Peracchi, A; Mozzarelli, A
Time-resolved fluorescence of tryptophan synthase.
Biophys Chem
61
9-22
1996
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Miyazawa, S; Jernigan, RL
Protein stability for single substitution mutants and the extent of local compactness in the denatured state.
Protein Eng
7
1209-20
1994
Escherichia virus T4
Automatic Mining of ENzyme DAta