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Information on EC 4.1.2.13 - fructose-bisphosphate aldolase and Organism(s) Arabidopsis thaliana

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.13 fructose-bisphosphate aldolase
IUBMB Comments
Also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
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Arabidopsis thaliana
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
aldolase, aldolase a, aldolase b, aldolase c, aldoa, fructose-1,6-bisphosphate aldolase, fructose-bisphosphate aldolase, aldob, fructose bisphosphate aldolase, fructose 1,6-bisphosphate aldolase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1,6-Diphosphofructose aldolase
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-
-
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37 kDa major allergen
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-
-
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41 kDa antigen
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-
-
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aldolase
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-
-
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aldolase, fructose diphosphate
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-
-
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ALDP
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-
-
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Brain-type aldolase
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-
-
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CE1
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-
-
-
CE2
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-
-
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Diphosphofructose aldolase
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-
-
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FBP aldolase
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-
-
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Fru-P2A
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-
-
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Fructoaldolase
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-
-
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Fructose 1,6-bisphosphate aldolase
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-
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Fructose 1,6-diphosphate aldolase
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-
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Fructose 1-monophosphate aldolase
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-
-
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Fructose 1-phosphate aldolase
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-
-
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Fructose bisphosphate aldolase
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-
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Fructose diphosphate aldolase
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-
-
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Fructose-1,6-bisphosphate triosephosphate-lyase
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-
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IgE-binding allergen
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-
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ketose 1-phosphate aldolase
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-
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Liver-type aldolase
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-
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Muscle-type aldolase
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-
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Phosphofructoaldolase
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-
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SMALDO
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-
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zymohexase
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
condensation
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)
Also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
CAS REGISTRY NUMBER
COMMENTARY hide
9024-52-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
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chloroplastic fructose 1,6-bisphosphate aldolase isoforms are methylated by protein-lysine methyltransferase LSMT. Trimethylation occurs at a conserved lysyl residue located close to the C terminus. Trimethylation does not modify the kinetic properties and tetrameric organization of the aldolases in vitro
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ALFP1_ARATH
399
0
42931
Swiss-Prot
Chloroplast (Reliability: 3)
ALFP2_ARATH
398
0
42988
Swiss-Prot
Chloroplast (Reliability: 2)
ALFP3_ARATH
391
0
42327
Swiss-Prot
Chloroplast (Reliability: 3)
ALFC4_ARATH
393
0
42906
Swiss-Prot
Mitochondrion (Reliability: 2)
ALFC5_ARATH
358
0
38294
Swiss-Prot
other Location (Reliability: 2)
ALFC6_ARATH
358
0
38387
Swiss-Prot
other Location (Reliability: 5)
ALFC7_ARATH
358
0
38810
Swiss-Prot
other Location (Reliability: 2)
ALFC8_ARATH
358
0
38540
Swiss-Prot
other Location (Reliability: 5)
A0A5S9Y1D7_ARATH
359
0
38630
TrEMBL
other Location (Reliability: 5)
Q56ZF2_ARATH
49
0
5252
TrEMBL
other Location (Reliability: 3)
F4IGL5_ARATH
389
0
41808
TrEMBL
Chloroplast (Reliability: 3)
C0Z2F2_ARATH
376
0
40466
TrEMBL
Chloroplast (Reliability: 3)
Q42207_ARATH
125
0
13603
TrEMBL
other Location (Reliability: 1)
A0A178VVW3_ARATH
391
0
42327
TrEMBL
Chloroplast (Reliability: 3)
A0A7G2F3W8_ARATH
413
0
44736
TrEMBL
Chloroplast (Reliability: 2)
A0A178UK16_ARATH
393
0
42918
TrEMBL
Mitochondrion (Reliability: 2)
A0A7G2F5I8_ARATH
822
1
90444
TrEMBL
Secretory Pathway (Reliability: 2)
F4JUJ5_ARATH
381
0
41344
TrEMBL
Chloroplast (Reliability: 2)
Q56Z19_ARATH
68
0
7402
TrEMBL
Mitochondrion (Reliability: 4)
A0A178UKM1_ARATH
359
0
38642
TrEMBL
other Location (Reliability: 5)
A0A7G2EUP3_ARATH
376
0
40554
TrEMBL
Secretory Pathway (Reliability: 2)
A0A178V694_ARATH
359
0
38814
TrEMBL
other Location (Reliability: 4)
A0A654FT01_ARATH
358
0
38810
TrEMBL
other Location (Reliability: 2)
A0A178UJU1_ARATH
267
0
28653
TrEMBL
other Location (Reliability: 1)
A0A5S9WW91_ARATH
391
0
42357
TrEMBL
Chloroplast (Reliability: 3)
A0A178V8L4_ARATH
358
0
38540
TrEMBL
other Location (Reliability: 5)
A0A178VN79_ARATH
399
0
42931
TrEMBL
Chloroplast (Reliability: 3)
A0A178UW98_ARATH
398
0
42988
TrEMBL
Chloroplast (Reliability: 2)
A0A178V385_ARATH
358
0
38294
TrEMBL
other Location (Reliability: 2)
A0A178UUL1_ARATH
104
0
11558
TrEMBL
other Location (Reliability: 2)
A0A1P8B8S7_ARATH
355
0
38436
TrEMBL
other Location (Reliability: 3)
A0A7G2F8A3_ARATH
359
0
38611
TrEMBL
other Location (Reliability: 5)
Q41992_ARATH
70
0
7872
TrEMBL
Mitochondrion (Reliability: 3)
A0A178VRN7_ARATH
358
0
38387
TrEMBL
other Location (Reliability: 5)
B3H6D7_ARATH
267
0
28720
TrEMBL
other Location (Reliability: 2)
A0A5S9XWH1_ARATH
379
0
41280
TrEMBL
other Location (Reliability: 2)
A0A1P8BBB5_ARATH
267
0
28641
TrEMBL
other Location (Reliability: 1)
F4IGL7_ARATH
311
0
33323
TrEMBL
Chloroplast (Reliability: 3)
A0A178UUU6_ARATH
358
0
38776
TrEMBL
other Location (Reliability: 2)
A0A1P8B8Q8_ARATH
358
0
38635
TrEMBL
other Location (Reliability: 2)
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
isoform FBA1 transcript levels are specifically reduced by abiotic stress
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture
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transgenic Nicotiana tabacum L. cv Xanthi expressing Arabidopsis plastid aldolase shows 1.4-1.9fold higher aldolase activities than wild-type, associated with enhanced growth, culminating in increased biomass, particularly under high CO2 concentration where the increase reached 2.2fold relative to wild-type plants. This increase is associated with a 1.5fold elevation of photosynthetic CO2 fixation in the transgenic plants. Overexpression results in a decrease in 3-phosphoglycerate and an increase in ribulose 1,5-bisphosphate and its immediate precursors in the Calvin cycle
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mininno, M.; Brugiere, S.; Pautre, V.; Gilgen, A.; Ma, S.; Ferro, M.; Tardif, M.; Alban, C.; Ravanel, S.
Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants
J. Biol. Chem.
287
21034-21044
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Uematsu, K.; Suzuki, N.; Iwamae, T.; Inui, M.; Yukawa, H.
Increased fructose 1,6-bisphosphate aldolase in plastids enhances growth and photosynthesis of tobacco plants
J. Exp. Bot.
63
3001-3009
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Moon, S.; Shin, D.; Kim, B.; Byun, M.
Putative fructose-1,6-bisphosphate aldolase 1 (AtFBA1) affects stress tolerance in yeast and Arabidopsis
J. Plant Biotechnol.
39
106-113
2012
Arabidopsis thaliana
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Manually annotated by BRENDA team