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Information on EC 3.5.99.6 - glucosamine-6-phosphate deaminase and Organism(s) Taeniopygia guttata

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EC Tree
IUBMB Comments
The enzyme uses ring opening and isomerization of the aldose-ketose type to convert the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol, which then hydrolyses to yield fructose 6-phosphate and ammonia. N-Acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.
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Taeniopygia guttata
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The taxonomic range for the selected organisms is: Taeniopygia guttata
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
gnpda2, glucosamine-6-phosphate deaminase, oscillin, gnpda1, gnpda, glucosamine-6-phosphate isomerase, glucosamine 6-phosphate deaminase, glcn6p deaminase, glucosamine 6-phosphate isomerase, glucosamine-6p deaminase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-amino-2-deoxy-D-glucose-6-phosphate ketol isomerase (deaminating)
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aminodeoxyglucosephosphate isomerase
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GlcN-6-P isomerase
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GlcN6P deaminase
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glucosamine 6-phosphate deaminase
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glucosamine 6-phosphate isomerase
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glucosamine phosphate deaminase
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glucosamine-6-phosphate deaminase
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glucosamine-P isomerase
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glucosaminephosphate isomerase
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GNPDA
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isomerase, glucosamine phosphate
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oscillin
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phoshoglucosamine isomerase
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phosphoglucosaminisomerase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
intramolecular oxidoreduction
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SYSTEMATIC NAME
IUBMB Comments
2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)
The enzyme uses ring opening and isomerization of the aldose-ketose type to convert the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol, which then hydrolyses to yield fructose 6-phosphate and ammonia. N-Acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.
CAS REGISTRY NUMBER
COMMENTARY hide
9013-10-9
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A674G8Z1_TAEGU
205
0
22914
TrEMBL
other Location (Reliability: 1)
A0A674HD98_TAEGU
145
0
16715
TrEMBL
other Location (Reliability: 1)
H0ZDN6_TAEGU
275
0
31067
TrEMBL
other Location (Reliability: 1)
H0YPH3_TAEGU
288
0
32163
TrEMBL
other Location (Reliability: 2)