Reference on EC 3.5.4.B9 - cytosine deaminase APOBEC3G and Organism(s) Homo sapiens
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topREF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chelico, L.; Prochnow, C.; Erie, D.A.; Chen, X.S.; Goodman, M.F.
Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G
J. Biol. Chem.
285
16195-16205
2010
Homo sapiens
Li, M.; Shandilya, S.M.; Carpenter, M.A.; Rathore, A.; Brown, W.L.; Perkins, A.L.; Harki, D.A.; Solberg, J.; Hook, D.J.; Pandey, K.K.; Parniak, M.A.; Johnson, J.R.; Krogan, N.J.; Somasundaran, M.; Ali, A.; Schiffer, C.A.; Harris, R.S.
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G
ACS Chem. Biol.
7
506-517
2012
Homo sapiens (Q9HC16)
Carpenter, M.A.; Rajagurubandara, E.; Wijesinghe, P.; Bhagwat, A.S.
Determinants of sequence-specificity within human AID and APOBEC3G
DNA Repair
9
579-587
2010
Homo sapiens (Q9HC16)
Demorest, Z.L.; Li, M.; Harris, R.S.
Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein
J. Biol. Chem.
286
26568-26575
2011
Homo sapiens, Mus musculus
Senavirathne, G.; Jaszczur, M.; Auerbach, P.A.; Upton, T.G.; Chelico, L.; Goodman, M.F.; Rueda, D.
Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution
J. Biol. Chem.
287
15826-15835
2012
Homo sapiens
Li, X.; Ma, J.; Zhang, Q.; Zhou, J.; Yin, X.; Zhai, C.; You, X.; Yu, L.; Guo, F.; Zhao, L.; Li, Z.; Zeng, Y.; Cen, S.
Functional analysis of the two cytidine deaminase domains in APOBEC3G
Virology
414
130-136
2011
Homo sapiens
Shlyakhtenko, L.S.; Lushnikov, A.Y.; Miyagi, A.; Li, M.; Harris, R.S.; Lyubchenko, Y.L.
Nanoscale structure and dynamics of ABOBEC3G complexes with single-stranded DNA
Biochemistry
51
6432-6440
2012
Homo sapiens (Q9HC16)
Jaszczur, M.; Bertram, J.G.; Pham, P.; Scharff, M.D.; Goodman, M.F.
AID and Apobec3G haphazard deamination and mutational diversity
Cell. Mol. Life Sci.
70
3089-3108
2013
Homo sapiens (Q9HC16), Homo sapiens
Olson, M.E.; Li, M.; Harris, R.S.; Harki, D.A..
Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold
ChemMedChem
8
112-117
2012
Homo sapiens
Coker, H.A.; Petersen-Mahrt, S.K.
The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action
DNA Repair
6
235-243
2006
Homo sapiens (Q9HC16)
Pham, P.; Chelico, L.; Goodman, M.F.
DNA deaminases AID and APOBEC3G act processively on single-stranded DNA
DNA Repair
6
689-692
2007
Homo sapiens (Q9HC16)
Furukawa, A.; Nagata, T.; Matsugami, A.; Habu, Y.; Sugiyama, R.; Hayashi, F.; Kobayashi, N.; Yokoyama, S.; Takaku, H.; Katahira, M.
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
EMBO J.
28
440-451
2009
Homo sapiens (Q9HC16)
Rausch, J.W.; Chelico, L.; Goodman, M.F.; Le Grice, S.F.
Dissecting APOBEC3G substrate specificity by nucleoside analog interference
J. Biol. Chem.
284
7047-7058
2009
Homo sapiens
Feng, Y.; Chelico, L.
Intensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain
J. Biol. Chem.
286
11415-11426
2011
Homo sapiens
Sadler, H.A.; Stenglein, M.D.; Harris, R.S.; Mansky, L.M.
APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis
J. Virol.
84
7396-7404
2012
Homo sapiens
Chelico, L.; Pham, P.; Calabrese, P.; Goodman, M.F.
APOBEC3G DNA deaminase acts processively 3' -> 5' on single-stranded DNA
Nat. Struct. Mol. Biol.
13
392-399
2006
Homo sapiens
Zhang, H.; Yang, B.; Pomerantz, R.J.; Zhang, C.; Arunachalam, S.C.; Gao, L.
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
Nature
424
94-98
2003
Homo sapiens
Holden, L.G.; Prochnow, C.; Chang, Y.P.; Bransteitter, R.; Chelico, L.; Sen, U.; Stevens, R.C.; Goodman, M.F.; Chen, X.S.
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications
Nature
456
121-124
2008
Homo sapiens (Q9HC16)
Suspene, R.; Sommer, P.; Henry, M.; Ferris, S.; Guetard, D.; Pochet, S.; Chester, A.; Navaratnam, N.; Wain-Hobson, S.; Vartanian, J.P.
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
Nucleic Acids Res.
32
2421-2429
2004
Homo sapiens (Q9HC16)
Monajemi, M.; Woodworth, C.F.; Benkaroun, J.; Grant, M.; Larijani, M.
Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment
Retrovirology
9
35
2012
Homo sapiens (Q9HC16)
Lu, X.; Zhang, T.; Xu, Z.; Liu, S.; Zhao, B.; Lan, W.; Wang, C.; Ding, J.; Cao, C.
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J. Biol. Chem.
290
4010-4021
2015
Homo sapiens (Q9HC16)
Holtz, C.M.; Sadler, H.A.; Mansky, L.M.
APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure
Nucleic Acids Res.
41
6139-6148
2013
Homo sapiens (Q9HC16)
Zhu, Y.P.; Peng, Z.G.; Wu, Z.Y.; Li, J.R.; Huang, M.H.; Si, S.Y.; Jiang, J.D.
Host APOBEC3G protein inhibits HCV replication through direct binding at NS3
PLoS ONE
10
e0121608
2015
Homo sapiens (Q9HC16)
Lu, X.; Zhang, T.; Xu, Z.; Liu, S.; Zhao, B.; Lan, W.; Wang, C.; Ding, J.; Cao, C.
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J. Biol. Chem.
290
4010-4021
2015
Homo sapiens (Q9HC16)
Adolph, M.B.; Love, R.P.; Chelico, L.
Biochemical basis of APOBEC3 deoxycytidine deaminase activity on diverse DNA substrates
ACS Infect. Dis.
4
224-238
2018
Homo sapiens (Q9HC16)
Ito, F.; Fu, Y.; Kao, S.A.; Yang, H.; Chen, X.S.
Family-wide comparative analysis of cytidine and methylcytidine deamination by eleven human APOBEC proteins
J. Mol. Biol.
429
1787-1799
2017
Homo sapiens (Q9HC16)
Maiti, A.; Myint, W.; Kanai, T.; Delviks-Frankenberry, K.; Sierra Rodriguez, C.; Pathak, V.K.; Schiffer, C.A.; Matsuo, H.
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with sDNA
Nat. Commun.
9
2460
2018
Homo sapiens (Q9HC16)
Wang, Y.; Wu, S.; Zheng, S.; Wang, S.; Wali, A.; Ezhilarasan, R.; Sulman, E.P.; Koul, D.; Alfred Yung, W.K.
APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death
Oncotarget
8
54285-54296
2017
Homo sapiens (Q9HC16), Homo sapiens
