Information on EC 3.5.3.3 - creatinase

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The expected taxonomic range for this enzyme is: Bacteria

EC NUMBER
COMMENTARY
3.5.3.3
-
RECOMMENDED NAME
GeneOntology No.
creatinase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of linear amidines
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Arginine and proline metabolism
-
creatinine degradation I
-
Glycine, serine and threonine metabolism
-
Metabolic pathways
-
SYSTEMATIC NAME
IUBMB Comments
creatine amidinohydrolase
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
CAH
Q7SIB5
-
CAH
Actinobacillus sp. CRH-211
Q7SIB5
-
-
Creatine amidinohydrolase
-
-
-
-
Creatine amidinohydrolase
-
-
Creatine amidinohydrolase
Q7SIB5
-
Creatine amidinohydrolase
Actinobacillus sp. CRH-211
-, Q7SIB5
-
-
CAS REGISTRY NUMBER
COMMENTARY
37340-58-2
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
subsp. denitrificans J9
-
-
Manually annotated by BRENDA team
CRH-104D
-
-
Manually annotated by BRENDA team
Acinetobacter sp. CRH-104D
CRH-104D
-
-
Manually annotated by BRENDA team
strain CRH-211
-
-
Manually annotated by BRENDA team
strain CRH-211
SwissProt
Manually annotated by BRENDA team
Actinobacillus sp. CRH-211
strain CRH-211
-
-
Manually annotated by BRENDA team
Actinobacillus sp. CRH-211
strain CRH-211
SwissProt
Manually annotated by BRENDA team
Alcaligenes sp. AK-2
AK-2
-
-
Manually annotated by BRENDA team
J5 and J11
-
-
Manually annotated by BRENDA team
B-068
-
-
Manually annotated by BRENDA team
Bacillus sp. B-068
B-068
-
-
Manually annotated by BRENDA team
U-188, ATCC 31200
-
-
Manually annotated by BRENDA team
var. naraensis C-83
-
-
Manually annotated by BRENDA team
wild-type enzyme and mutant enzymes A109V, V355M, V181I, A109V/V355M, A109V/V355M/V182I
-
-
Manually annotated by BRENDA team
Pseudomonas putida NTU-8
NTU-8
-
-
Manually annotated by BRENDA team
H21 AKU876
-
-
Manually annotated by BRENDA team
Pseudomonas sp. C-83
C-83
-
-
Manually annotated by BRENDA team
Pseudomonas sp. H21 AKU876
H21 AKU876
-
-
Manually annotated by BRENDA team
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
creatine + H2O
sarcosine + urea
show the reaction diagram
Q7SIB5
-
-
-
?
creatine + H2O
sarcosine + urea
show the reaction diagram
-
-
-
-
?
creatine + H2O
?
show the reaction diagram
-
degradation of creatine, inducible enzyme
-
-
-
creatine + H2O
sarcosine + urea
show the reaction diagram
Actinobacillus sp. CRH-211
Q7SIB5
-
-
-
?
creatine + H2O
?
show the reaction diagram
Arthrobacter sp. J5 J11
-
degradation of creatine, inducible enzyme
-
-
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
N3-
A7LCN3
1 mM, 104% of initial activity
pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6
8
Q7SIB5
electrode matrix suitable for enzyme applications at neutral condition
6.5
9.5
-
pH 6.5: about 70% of maximal activity, pH 9.5: about 30% of maximal activity
TEMPERATURE RANGE
TEMPERATURE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
26
43
Q7SIB5
optimum temperature range calculated between 32 and 34°C due to the increased kinetic energy of the reacting molecules, current of the bioelectrode measured at different temperatures ranging from 26 to 43°C in the presence of creatine 150 microM and a phosphate buffer (50 mM, pH 7.0)