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Aberrant Crypt Foci
Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-?1and HES-1 transcripts in 1, 2-dimethylhydrazine-colon carcinogenesis in mice.
Acidosis
Long lasting protective effects of early l-arginine treatment on endothelium in an in vitro study.
Acute Kidney Injury
Melatonin reduces nitric oxide via increasing arginase in rhabdomyolysis-induced acute renal failure in rats.
Acute Lung Injury
Acute Lung Injury-Induced Collagen Deposition is Associated with Elevated Asymmetric Dimethylarginine and Arginase Activity.
Acute Lung Injury
Arginase 1: an unexpected mediator of pulmonary capillary barrier dysfunction in models of acute lung injury.
Adenocarcinoma
Arginase activity and nucleic acid content in mamary adenocarcinoma and normal homologous tissue of C3H mice.
Adenocarcinoma
Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines.
Adenocarcinoma
Arginase isoforms in human colorectal cancer.
Adenocarcinoma
Arginase-1 is a more sensitive marker of hepatic differentiation than HepPar-1 and glypican-3 in fine-needle aspiration biopsies.
Adenocarcinoma
Arginase-1 is frequently positive in hepatoid adenocarcinomas.
Adenocarcinoma
Arginase-1: a highly specific marker separating pancreatic adenocarcinoma from hepatocellular carcinoma.
Adenocarcinoma
CD13(hi) Neutrophil-like myeloid-derived suppressor cells exert immune suppression through Arginase 1 expression in pancreatic ductal adenocarcinoma.
Adenocarcinoma
Circulating and tumor-infiltrating arginase 1-expressing cells in gastric adenocarcinoma patients were mainly immature and monocytic Myeloid-derived suppressor cells.
Adenocarcinoma
Clinical significance of arginase in colorectal cancer.
Adenocarcinoma
DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
Adenocarcinoma
Early detection of pancreatic cancers in liquid biopsies by ultrasensitive fluorescence nanobiosensors.
Adenocarcinoma
Effects of adrenocorticotropic hormone (ACTH), cortisone, and arginase on growth of transplanted mammary adenocarcinoma in C3H mice.
Adenocarcinoma
Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas.
Adenocarcinoma
Hepatocyte differentiation markers in adenocarcinoma of the prostate: hepatocyte paraffin 1 but not arginase-1 is specifically expressed in a subset of prostatic adenocarcinoma.
Adenocarcinoma
HepPar-1 and Arginase-1 Immunohistochemistry in Adenocarcinoma of the Small Intestine and Ampullary Region.
Adenocarcinoma
Immunohistochemical study of arginase in cancer of the stomach.
Adenocarcinoma
Inhibitory effects of arginase on mammary adenocarcinoma transplants in strain "A" mice.
Adenocarcinoma
Nitric oxide synthase, arginase and cyclooxygenase are involved in muscarinic receptor activation in different murine mammary adenocarcinoma cell lines.
Adenocarcinoma
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase.
Adenocarcinoma
The Diagnostic Value of Arginase-1, FTCD, and MOC-31 Expression in Early Detection of Hepatocellular Carcinoma (HCC) and in Differentiation Between HCC and Metastatic Adenocarcinoma to the Liver.
Adenocarcinoma of Lung
Arginase-1 and HepPar-1 expression in fine-needle aspiration specimens of primary lung adenocarcinoma.
Adenocarcinoma of Lung
Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models.
Adenocarcinoma of Lung
Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity.
Adenocarcinoma, Papillary
Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas.
Adenomyoma
Immunohistochemical results and case report of an incidental finding of uterine polypoid adenomyoma after long-time therapy for metrorrhagia.
Adrenoleukodystrophy
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
Airway Obstruction
Arginase 1 and arginase 2 variations associate with asthma, asthma severity and beta2 agonist and steroid response.
Airway Obstruction
Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation.
Airway Obstruction
Asymmetric Dimethylarginine in Chronic Obstructive Pulmonary Disease (ADMA in COPD).
Albuminuria
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Alopecia
[Clinical and biochemical alterations in rats treated with high doses of vitamin A]
Alphavirus Infections
Genetic Ablation of Arginase 1 in Macrophages and Neutrophils Enhances Clearance of an Arthritogenic Alphavirus.
Alzheimer Disease
Alzheimer's disease as a chronic maladaptive polyamine stress response.
Alzheimer Disease
Arginase Inhibition Supports Survival and Differentiation of Neuronal Precursors in Adult Alzheimer's Disease Mice.
Alzheimer Disease
Bioinformatics methods in drug repurposing for Alzheimer's disease.
Alzheimer Disease
L-Norvaline, a new therapeutic agent against Alzheimer's disease.
Alzheimer Disease
Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-? Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.
Alzheimer Disease
The Role of Arginine-Nitric Oxide Pathway in Patients with Alzheimer Disease.
Amebiasis
Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
amino-acid n-acetyltransferase deficiency
Genetic approach to prenatal diagnosis in urea cycle defects.
amino-acid n-acetyltransferase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Amyloidosis
Arginase 1 Insufficiency Precipitates Amyloid-? Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis.
Amyotrophic Lateral Sclerosis
Alterations of arginase activity in scrapie-infected mice and in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Arginase-1 expressing microglia in close proximity to motor neurons were increased early in disease progression in canine degenerative myelopathy, a model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase.
Amyotrophic Lateral Sclerosis
[Study of cerebrospinal fluid arginase activity in the diagnosis of amyotrophic lateral sclerosis]
Anaplasmosis
Enzymes of oxidant defence system of leucocytes and erythrocytes in bovine anaplasmosis.
Anemia
Arginase levels and their association with Th17-related cytokines, soluble adhesion molecules (sICAM-1 and sVCAM-1) and hemolysis markers among steady-state sickle cell anemia patients.
Anemia
Pattern of hemolysis parameters and association with fetal hemoglobin in sickle cell anemia patients in steady state.
Anemia
[Arginase activity in plasma and erythrocytes in children with hematologic diseases]
Anemia, Hemolytic
[Arginase activity in plasma and erythrocytes in children with hematologic diseases]
Anemia, Hypochromic
Mode of Action of the Toxin from Pseudomonas phaseolicola: I. Toxin Specificity, Chlorosis, and Ornithine Accumulation.
Anemia, Pernicious
The arginase activity of erythrocytes and leukocytes with particular reference to pernicious anemia and thalassemia major.
Anemia, Sickle Cell
Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.
Anemia, Sickle Cell
Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension, and Vascular Stiffness in Transgenic Sickle Cell Mice.
Anemia, Sickle Cell
Arginase levels and their association with Th17-related cytokines, soluble adhesion molecules (sICAM-1 and sVCAM-1) and hemolysis markers among steady-state sickle cell anemia patients.
Anemia, Sickle Cell
Cysteine-iron promotes arginase activity by driving the Fenton reaction.
Anemia, Sickle Cell
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
Anemia, Sickle Cell
Growth inhibitory and differentiation effects of chloroquine and its analogue on human leukemic cells potentiate fetal hemoglobin production by targeting the polyamine pathway.
Anemia, Sickle Cell
Hemolysis-associated pulmonary hypertension in thalassemia.
Anemia, Sickle Cell
In vitro evidence of the inhibitory capacity of chloroquine on arginase activity in sickle erythrocytes.
Anemia, Sickle Cell
Influence of ?S-Globin Haplotypes and Hydroxyurea on Arginase I Levels in Sickle Cell Disease.
Anemia, Sickle Cell
Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease.
Anemia, Sickle Cell
Modulation of erythrocyte arginase activity in sickle cell disease patients during hydroxyurea therapy.
Anemia, Sickle Cell
Pattern of hemolysis parameters and association with fetal hemoglobin in sickle cell anemia patients in steady state.
Anemia, Sickle Cell
Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.
Anemia, Sideroblastic
A case of sideroblastic anaemia associated with marked elevation of erythrocytic arginase activity.
Angina Pectoris
Early diagnosis of myocardial infarction by arginase activity determination.
Aortic Aneurysm, Abdominal
Transforming growth factor ? neutralization finely tunes macrophage phenotype in elastase-induced abdominal aortic aneurysm and is associated with an increase of arginase 1 expression in the aorta.
arginase deficiency
"Cerebral Palsy" in a Patient With Arginase Deficiency.
arginase deficiency
A long-term survival case of arginase deficiency with severe multicystic white matter and compound mutations.
arginase deficiency
A new case of arginase deficiency in a Spanish male.
arginase deficiency
A new French-Canadian family affected by hyperargininaemia.
arginase deficiency
A new metabolic disorder in human cationic amino acid transporter-2 that mimics arginase 1 deficiency in newborn screening.
arginase deficiency
A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
arginase deficiency
A novel mutation in ARG1 gene is responsible for arginase deficiency in an Asian family.
arginase deficiency
A patient with arginase deficiency and episodic hyperammonemia successfully treated with menses cessation.
arginase deficiency
A simple quantitative micromethod of arginase assay in blood spots dried on filter paper.
arginase deficiency
A simple screening test for arginase deficiency (hyperargininemia).
arginase deficiency
A simple spot-test for the detection of erythrocyte arginase deficiency.
arginase deficiency
A successful trial of enzyme replacement therapy in a case of argininemia.
arginase deficiency
AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse.
arginase deficiency
Adult-onset arginase deficiency.
arginase deficiency
Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency.
arginase deficiency
Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry.
arginase deficiency
Anesthesia in a patient with arginase deficiency: implications and management.
arginase deficiency
Anesthetic management of a patient with arginase deficiency undergoing liver transplantation.
arginase deficiency
Anesthetic management of a pediatric patient with arginase-1 deficiency undergoing strabismus operation: a case report.
arginase deficiency
Arginase deficiency and phenylketonuria.
arginase deficiency
Arginase deficiency in a 12-year-old boy with mild impairment of intellectual function.
arginase deficiency
Arginase deficiency in Macaca fascicularis. I. Arginase activity and arginine concentration in erythrocytes and liver.
arginase deficiency
Arginase deficiency in multiple tissues in argininemia.
arginase deficiency
Arginase deficiency in two brothers.
arginase deficiency
Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme.
arginase deficiency
Arginase Deficiency Presenting as Acute Encephalopathy.
arginase deficiency
Arginase deficiency presenting as cerebral palsy.
arginase deficiency
Arginase deficiency presenting with cerebral oedema and failure to thrive.
arginase deficiency
Arginase deficiency presenting with convulsions.
arginase deficiency
Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema.
arginase deficiency
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
arginase deficiency
Arginase deficiency.
arginase deficiency
Arginase I deficiency: Severe infantile presentation with hyperammonemia: More common than reported?
arginase deficiency
Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity.
arginase deficiency
Arginase-1 deficiency in neural cells does not contribute to neurodevelopment or functional outcomes after sciatic nerve injury.
arginase deficiency
Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia.
arginase deficiency
Arginase-1 deficiency.
arginase deficiency
Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris.
arginase deficiency
Arginase-2 mediates renal ischemia-reperfusion injury.
arginase deficiency
Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity.
arginase deficiency
Arginine to ornithine ratio as a diagnostic marker in patients with positive newborn screening for hyperargininemia.
arginase deficiency
Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl.
arginase deficiency
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
arginase deficiency
Biomarkers identified in inborn errors for lysine, arginine, and ornithine.
arginase deficiency
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
arginase deficiency
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.
arginase deficiency
Case series of Arginase 1 deficiency: Expanding the spectrum in hyperargininemia.
arginase deficiency
Clinical consequences of urea cycle enzyme deficiencies and potential links to arginine and nitric oxide metabolism.
arginase deficiency
Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency.
arginase deficiency
Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency.
arginase deficiency
Clinical, biochemical, and molecular spectrum of hyperargininemia due to arginase I deficiency.
arginase deficiency
Comparison of arginase activity in red blood cells of lower mammals, primates, and man: evolution to high activity in primates.
arginase deficiency
Creatine metabolism and the urea cycle.
arginase deficiency
Creatine metabolism in patients with urea cycle disorders.
arginase deficiency
Delivery of cytosolic liver arginase into the mitochondrial matrix space: a possible novel site for gene replacement therapy.
arginase deficiency
Different missense mutations in PDR1 and PDR3 genes from clotrimazole-resistant sake yeast are responsible for pleiotropic drug resistance and improved fermentative activity.
arginase deficiency
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
arginase deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
arginase deficiency
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
arginase deficiency
Excretion of guanidino-derivates in urine of hyperargininemic patients.
arginase deficiency
Five novel mutations in ARG1 gene in Chinese patients of argininemia.
arginase deficiency
Fluorometric micromethod for determination of arginase activity in dried blood spots on filter paper.
arginase deficiency
Generation of a mouse model for arginase II deficiency by targeted disruption of the arginase II gene.
arginase deficiency
Genetic approach to prenatal diagnosis in urea cycle defects.
arginase deficiency
Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis.
arginase deficiency
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development.
arginase deficiency
Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice.
arginase deficiency
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
arginase deficiency
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
arginase deficiency
Hyperargininemia due to liver arginase deficiency.
arginase deficiency
Hyperargininemia with arginase deficiency.
arginase deficiency
Hyperargininemia, epilepsy and the metabolism of guanidino compounds.
arginase deficiency
Hyperargininemia.
arginase deficiency
Hyperargininemia: the rat as a model for the human disease and the comparative response to enzyme replacement therapy with free arginase and arginase-loaded erythrocytes in vivo.
arginase deficiency
Hyperargininemic Encephalopathy with Unique Clinical Presentation and Novel Genetic Mutations.
arginase deficiency
Impact of arginase II on CBF in experimental cortical impact injury in mice using MRI.
arginase deficiency
Impaired neurotransmitter amine metabolism in arginase deficiency.
arginase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
arginase deficiency
Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia.
arginase deficiency
Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism.
arginase deficiency
Influence of arginase deficiency on amino acid concentrations in sheep erythrocytes with a normal and with a defective transport system for amino acids [proceedings]
arginase deficiency
Isoenzyme pattern and immunological properties of arginase in normal and hyperargininemia fibroblasts.
arginase deficiency
Isotropic growth of spores and salt tolerance in Aspergillus nidulans
arginase deficiency
Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice.
arginase deficiency
Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.
arginase deficiency
Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse.
arginase deficiency
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
arginase deficiency
Liver fibrosis in arginase deficiency.
arginase deficiency
Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency.
arginase deficiency
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
arginase deficiency
Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy.
arginase deficiency
Loss of function mutations in conserved regions of the human arginase I gene.
arginase deficiency
Metabolic Serendipities of Expanded Newborn Screening.
arginase deficiency
Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.
arginase deficiency
Molecular genetic study of human arginase deficiency.
arginase deficiency
Mouse model for human arginase deficiency.
arginase deficiency
Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice.
arginase deficiency
Neonatal cholestasis: an uncommon presentation of hyperargininemia.
arginase deficiency
Newborn screening for hyperargininemia due to arginase 1 deficiency.
arginase deficiency
Novel ARG1 variants identified in a patient with arginase 1 deficiency.
arginase deficiency
Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.
arginase deficiency
Orotic acid excretion and arginine metabolism.
arginase deficiency
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
arginase deficiency
Polyamine dependence of Chinese hamster ovary cells in serum-free culture is due to deficient arginase activity.
arginase deficiency
Prenatal diagnosis for arginase deficiency by second-trimester fetal erythrocyte arginase assay and first-trimester ARG1 mutation analysis.
arginase deficiency
Prenatal diagnosis for arginase deficiency: a case study.
arginase deficiency
Prenatal diagnosis of the urea cycle diseases: a survey of the European cases.
arginase deficiency
Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency.
arginase deficiency
Properties of fetal and adult red blood cell arginase: a possible prenatal diagnostic test for arginase deficiency.
arginase deficiency
Pteridines and mono-amines: relevance to neurological damage.
arginase deficiency
Recurrent unexplained hyperammonemia in an adolescent with arginase deficiency.
arginase deficiency
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
arginase deficiency
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
arginase deficiency
Review of Multi-Modal Imaging in Urea Cycle Disorders: The Old, the New, the Borrowed, and the Blue.
arginase deficiency
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
arginase deficiency
Short-term Correction of Arginase Deficiency in a Neonatal Murine Model With a Helper-dependent Adenoviral Vector.
arginase deficiency
Sodium phenylbutyrate improved the clinical state in an adult patient with arginase 1 deficiency.
arginase deficiency
Strategies to rescue the consequences of inducible arginase-1 deficiency in mice.
arginase deficiency
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine.
arginase deficiency
The human arginases and arginase deficiency.
arginase deficiency
The nutritional management of urea cycle disorders.
arginase deficiency
Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring.
arginase deficiency
Treatment of hyperargininaemia due to arginase deficiency with a chemically defined diet.
arginase deficiency
Unsuccessful trial of gene replacement in arginase deficiency.
arginase deficiency
Untargeted metabolomic profiling reveals multiple pathway perturbations and new clinical biomarkers in urea cycle disorders.
arginase deficiency
Urinary pyrimidine excretion in arginase deficiency.
arginase deficiency
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
arginase deficiency
[Arginase deficiency, congenital hypothyroidism and hepatic fibrosis]
arginase deficiency
[Arginase deficiency]
arginase deficiency
[Hyperargininemia with arginase deficiency. A new familial metabolic disease. II. Biochemical studies.]
arginase deficiency
[Hyperargininemia wityh arginase deficiency. A new familial metabolic disease. I. Clinical studies]
arginase deficiency
[Late diagnosis of congenital argininemia during administration of sodium valproate]
arginase deficiency
[Proposal for a diet treatment in arginase deficiency]
arginase deficiency
[Seven patients of argininemia with spastic tetraplegia as the first and major symptom and prenatal diagnosis of two fetuses with high risk].
arginase deficiency
[The dibasic amino acid metabolic disorders]
argininosuccinate lyase deficiency
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
argininosuccinate lyase deficiency
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
argininosuccinate lyase deficiency
Genetic approach to prenatal diagnosis in urea cycle defects.
argininosuccinate lyase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
argininosuccinate lyase deficiency
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
argininosuccinate lyase deficiency
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
argininosuccinate synthase deficiency
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
argininosuccinate synthase deficiency
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
argininosuccinate synthase deficiency
Clinical and biochemical characteristics of patients with urea cycle disorders in a developing country.
argininosuccinate synthase deficiency
Genetic approach to prenatal diagnosis in urea cycle defects.
argininosuccinate synthase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
argininosuccinate synthase deficiency
Liver transplantation may prevent neurodevelopmental deterioration in high-risk patients with urea cycle disorders.
argininosuccinate synthase deficiency
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
argininosuccinate synthase deficiency
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
argininosuccinate synthase deficiency
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
Argininosuccinic Aciduria
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
Argininosuccinic Aciduria
ARGININOSUCCINIC ACIDURIA. ARGININOSUCCINASE AND ARGINASE IN HUMAN BLOOD CELLS.
Argininosuccinic Aciduria
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
Argininosuccinic Aciduria
Creatine metabolism in patients with urea cycle disorders.
Argininosuccinic Aciduria
Genetic approach to prenatal diagnosis in urea cycle defects.
Argininosuccinic Aciduria
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Argininosuccinic Aciduria
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
Argininosuccinic Aciduria
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
Argininosuccinic Aciduria
Prenatal diagnosis of the urea cycle diseases: a survey of the European cases.
Arrhythmias, Cardiac
Arginase induction and activation during ischemia and reperfusion and functional consequences for the heart.
Arthritis
Diclofenac but not celecoxib improves endothelial function in rheumatoid arthritis: A study in adjuvant-induced arthritis.
Arthritis
Endothelial dysfunction in rat adjuvant-induced arthritis: Up-regulation of the vascular arginase pathway.
Arthritis
Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide.
Arthritis
Modulatory effect of eugenol on arginase, nucleotidase, and adenosine deaminase activities of platelets in a carrageenan-induced arthritis rat model: A possible anti-arthritic mechanism of eugenol.
Arthritis
Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages.
Arthritis
The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.
Arthritis
Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.
Arthritis
Treatment with the arginase inhibitor Nw-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis.
Arthritis
Vascular Arginase Is a Relevant Target to Improve Cerebrovascular Endothelial Dysfunction in Rheumatoid Arthritis: Evidence from the Model of Adjuvant-Induced Arthritis.
Arthritis, Gouty
[Effect of Electroacupuncture on Synovial M 1/M 2 Macrophage Polarization in Rats with Acute Gouty Arthritis].
Arthritis, Reactive
[SPECIES COMPOSITION OF INFECTIOUS FACTORS THAT CAUSE THE REACTIVE ARTHRITIS DEVELOPMENT AND THEIR EFFECT ON ARGINASE-NO-SYNTHASE REGULATORY SYSTEM OF PERIPHERAL BLOOD LYMPHOCYTES].
Arthritis, Rheumatoid
Arginase levels are increased in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Changes in the pattern of cytokine production from peripheral blood mononuclear cells in patients with rheumatoid arthritis treated with infliximab and their relation to plasma arginase activity.
Arthritis, Rheumatoid
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
Arthritis, Rheumatoid
Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide.
Arthritis, Rheumatoid
Relationship between synovial fluid and plasma manganese, arginase, and nitric oxide in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
TNF? induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNF? antibodies.
Arthritis, Rheumatoid
Vascular Arginase Is a Relevant Target to Improve Cerebrovascular Endothelial Dysfunction in Rheumatoid Arthritis: Evidence from the Model of Adjuvant-Induced Arthritis.
Asthma
2-Aminoimidazole Amino Acids as Inhibitors of the Binuclear Manganese Metalloenzyme Human Arginase I.
Asthma
Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice.
Asthma
Airway arginase expression and N?-hydroxy-nor-arginine effect on methacholine-induced bronchoconstriction differentiate Lewis and Fischer rat strains.
Asthma
Alterations of the arginine metabolome in asthma.
Asthma
Anti-inflammatory Effect of Arginase Inhibitor and Corticosteroid on Airway Allergic Reactions in a Dermatophogoides farinae-induced NC/Nga Mouse Model.
Asthma
Arginase 1 activity worsens lung-protective immunity against Streptococcus pneumoniae infection.
Asthma
Arginase 1 and arginase 2 variations associate with asthma, asthma severity and beta2 agonist and steroid response.
Asthma
Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
Asthma
Arginase activity differs with allergen in the effector phase of ovalbumin- versus trimellitic anhydride-induced asthma.
Asthma
Arginase and arginine dysregulation in asthma.
Asthma
Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness.
Asthma
Arginase and pulmonary diseases.
Asthma
Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.
Asthma
Arginase inhibition prevents inflammation and remodeling in a Guinea pig model of chronic obstructive pulmonary disease.
Asthma
Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation.
Asthma
Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma.
Asthma
Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives.
Asthma
Arginase: marker, effector, or candidate gene for asthma?
Asthma
Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences.
Asthma
Arginine and asthma.
Asthma
Arginine homeostasis in allergic asthma.
Asthma
Arginine metabolic control of airway inflammation.
Asthma
Arginine metabolic endotypes related to asthma severity.
Asthma
Arginine Therapy for Lung Diseases.
Asthma
Association of increased risk of asthma with elevated arginase & interleukin-13 levels in serum & rs2781666 G/T genotype of arginase I.
Asthma
Asthma in sickle cell disease.
Asthma
Asthma management: reinventing the wheel in sickle cell disease.
Asthma
Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma.
Asthma
Beneficial effects of arginase inhibition and inhaled l-arginine administration on airway histology in a murine model of chronic asthma.
Asthma
Binding of ?,?-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design.
Asthma
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.
Asthma
cNOS-iNOS paradigm and arginase in asthma.
Asthma
Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma.
Asthma
Decreased arginine bioavailability and increased serum arginase activity in asthma.
Asthma
Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model.
Asthma
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis.
Asthma
Effect of personal exposure to black carbon on changes in allergic asthma gene methylation measured 5 days later in urban children: importance of allergic sensitization.
Asthma
Effects of inhaled L-arginine administration in a murine model of acute asthma.
Asthma
Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice.
Asthma
Enhancer-mediated control of macrophage-specific arginase I expression.
Asthma
Evaluation of oxidative-antioxidative status and the L-arginine-nitric oxide pathway in asthmatic patients.
Asthma
Exposure to traffic-related air pollution and changes in exhaled nitric oxide and DNA methylation in arginase and nitric oxide synthase in children with asthma.
Asthma
Functionally Important Role for Arginase 1 in the Airways Hyperresponsiveness of Asthma.
Asthma
Genetic polymorphisms in arginase I and II and childhood asthma and atopy.
Asthma
Glucocorticoid inhibition of interleukin-4 (IL-4) and interleukin-13 (IL-13) induced up-regulation of arginase in rat airway fibroblasts.
Asthma
High Serum Arginase I Levels in Asthma: its Correlation with High-Sensitivity C-Reactive Protein.
Asthma
Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma.
Asthma
Impact of substrate protonation and tautomerization States on interactions with the active site of arginase I.
Asthma
Increased arginase activity contributes to airway remodelling in chronic allergic asthma.
Asthma
Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness.
Asthma
Increased expression of arginase I and II in allergic nasal mucosa.
Asthma
Increased mitochondrial arginine metabolism supports bioenergetics in asthma.
Asthma
Increased Ornithine-Derived Polyamines cause Airways Hyperresponsiveness in a Mouse Model of Asthma.
Asthma
Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I.
Asthma
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration.
Asthma
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.
Asthma
Inhibition of phosphodiesterase 4 amplifies cytokine-dependent induction of arginase in macrophages.
Asthma
Insights on the participation of Glu256 and Asp204 in the oligomeric structure and cooperative effects of human arginase type I.
Asthma
l-Arginine administration attenuates airway inflammation by altering l-arginine metabolism in an NC/Nga mouse model of asthma.
Asthma
L-Arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction.
Asthma
Mapping Arginase Expression with 18F-Fluorinated Late-Generation Arginase Inhibitors Derived from Quaternary ?-Amino Acids.
Asthma
Mechanisms of occupational asthma: Not all allergens are equal.
Asthma
Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma.
Asthma
Modeling gas phase nitric oxide release in lung epithelial cells.
Asthma
Mouse models of asthma: can they give us mechanistic insights into the role of nitric oxide?
Asthma
Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4.
Asthma
New Strategies for the Treatment of Pulmonary Hypertension in Sickle Cell Disease : The Rationale for Arginine Therapy.
Asthma
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
Asthma
Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation.
Asthma
Nitric oxide in asthma physiopathology.
Asthma
Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors.
Asthma
Pharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In Vivo.
Asthma
Plasma arginine metabolites reflect airway dysfunction in a murine model of allergic airway inflammation.
Asthma
Pollutant particles induce arginase II in human bronchial epithelial cells.
Asthma
Probing the specificity determinants of amino acid recognition by arginase.
Asthma
Recent Patents in Allergy/Immunology: Use of arginase inhibitors in the treatment of asthma and allergic rhinitis.
Asthma
Regulation of nitric oxide generation by up-regulated arginase I in rat spinal cord injury.
Asthma
Relationship among manganese, arginase, and nitric oxide in childhood asthma.
Asthma
Relationship between arginase genes polymorphisms and preschool wheezing phenotypes.
Asthma
Relationship between serum arginase I and l-arginine or exhaled nitric oxide in asthma.
Asthma
Resistin-Like Molecule Alpha Regulates IL-13-Induced Chemokine Production but not Allergen-Induced Airway Responses.
Asthma
Role of arginase in asthma: potential clinical applications.
Asthma
Roles of arginase variants, atopy, and ozone in childhood asthma.
Asthma
Short-term exposure to PM2.5 and vanadium and changes in asthma gene DNA methylation and lung function decrements among urban children.
Asthma
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Asthma
Small-molecule arginase inhibitors.
Asthma
Synthesis and evaluation of new omega-borono-alpha-amino acids as rat liver arginase inhibitors.
Asthma
Targeting arginase and nitric oxide metabolism in chronic airway diseases and their co-morbidities.
Asthma
TGF-{beta}2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells.
Asthma
Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity.
Asthma
The effects of WW2/WW3 domains of Smurf2 molecule on TGF-? signaling and arginase I gene expression.
Asthma
The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Asthma
The role of polymorphic variants of arginase genes (ARG1, ARG2) involved in beta-2-agonist metabolism in the development and course of asthma.
Asthma
The therapeutic potential of drugs targeting the arginase pathway in asthma.
Asthma
Transiently, paralleled upregulation of arginase and nitric oxide synthase and the effect of both enzymes on the pathology of asthma.
Asthma
[Arginine metabolism in bronchial asthma]
Asthma
[Carbamoyl ornithine transferase, arginase and cobalt-activated acylase in patients during asthma attacks or patients with respiratory failure]
Asthma
[Sputum arginase activity in bronchial asthma]
Atherosclerosis
ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis.
Atherosclerosis
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.
Atherosclerosis
Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis.
Atherosclerosis
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Atherosclerosis
Arginase as a target for treatment of myocardial ischemia-reperfusion injury.
Atherosclerosis
Arginase II Contributes to the Ca2+/CaMKII/eNOS Axis by Regulating Ca2+ Concentration Between the Cytosol and Mitochondria in a p32-Dependent Manner.
Atherosclerosis
Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica.
Atherosclerosis
Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis.
Atherosclerosis
Arginase II: Atherogenesis Beyond Enzyme Activity.
Atherosclerosis
Arginase Inhibition by Ethylacetate Extract of Caesalpinia sappan Lignum Contributes to Activation of Endothelial Nitric Oxide Synthase.
Atherosclerosis
Arginase type I as a marker of coronary heart disease in hemodialysis patients.
Atherosclerosis
Association of arginase 1 gene polymorphisms with the risk of myocardial infarction and common carotid intima media thickness.
Atherosclerosis
Binding of ?,?-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design.
Atherosclerosis
Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
Atherosclerosis
Early obesity leads to increases in hepatic arginase I and related systemic changes in nitric oxide and L-arginine metabolism in mice.
Atherosclerosis
Endothelial arginase II and atherosclerosis.
Atherosclerosis
Endothelial arginase II: a novel target for the treatment of atherosclerosis.
Atherosclerosis
Endothelial arginase: a new target in atherosclerosis.
Atherosclerosis
Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques.
Atherosclerosis
Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis.
Atherosclerosis
Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance.
Atherosclerosis
Identification of macrophage arginase I as a new candidate gene of atherosclerosis resistance.
Atherosclerosis
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Atherosclerosis
Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit.
Atherosclerosis
Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling.
Atherosclerosis
LXR{alpha} Regulates Macrophage Arginase 1 Through PU.1 and Interferon Regulatory Factor 8.
Atherosclerosis
Macrophage plasticity in experimental atherosclerosis.
Atherosclerosis
Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism.
Atherosclerosis
Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling.
Atherosclerosis
p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs.
Atherosclerosis
Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity.
Atherosclerosis
Poly(ADP-ribose) polymerase 1 deficiency increases nitric oxide production and attenuates aortic atherogenesis through downregulation of arginase II.
Atherosclerosis
Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers.
Atherosclerosis
Possible contribution of hepatocyte secretion to the elevation of plasma exosomal arginase-1 in high-fat diet-fed mice.
Atherosclerosis
Probing the specificity determinants of amino acid recognition by arginase.
Atherosclerosis
Regulation of arginase pathway in response to wall shear stress.
Atherosclerosis
Role of arginase in vessel wall remodeling.
Atherosclerosis
Selective Endothelial Overexpression of Arginase II Induces Endothelial Dysfunction and Hypertension and Enhances Atherosclerosis in Mice.
Atherosclerosis
The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Atherosclerosis
Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction.
Atherosclerosis
Transcriptional regulation of endothelial arginase 2 by histone deacetylase 2.
Atherosclerosis
Transcriptional regulation of macrophage arginase 1 expression and its role in atherosclerosis.
Atherosclerosis
[Arginase, nitrates, and nitrites in the blood plasma and erythrocytes in hypertension and after therapy with lisinopril and simvastatin].
Atrioventricular Block
Atrial Sources of Reactive Oxygen Species Vary With the Duration and Substrate of Atrial Fibrillation: Implications for the Antiarrhythmic Effect of Statins.
Autoimmune Diseases
Amino acid metabolism as drug target in autoimmune diseases.
Autoimmune Diseases
Deficient Arginase II Expression without Alteration in Arginase I Expression Attenuated Experimental Autoimmune Encephalomyelitis in Mice.
Autoimmune Diseases
Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis.
Autoimmune Diseases
Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo.
Azoospermia
[Importance of arginine content and arginase activity in fertility]
Azotemia
Effect of chronic renal failure on arginase and argininosuccinate synthetase expression.
Bacterial Infections
Arginase modulates Salmonella induced nitric oxide production in RAW264.7 macrophages and is required for Salmonella pathogenesis in mice model of infection.
Bacterial Infections
Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection.
Bacterial Infections
Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulator.
Bacterial Infections
Reduction of salivary arginine catabolic activity through periodontal therapy.
Bacterial Infections
Smoking increases salivary arginase activity in patients with dental implants.
beta-Thalassemia
The arginase activity of erythrocytes and leukocytes with particular reference to pernicious anemia and thalassemia major.
Blister
Arginase activity and polyamine biosynthesis in psoriasis.
Brain Diseases
Arginase Deficiency Presenting as Acute Encephalopathy.
Brain Diseases
Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema.
Brain Diseases
Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues.
Brain Diseases
Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.
Brain Diseases
Molecular pathways differentiate hepatitis C virus (HCV) recurrence from acute cellular rejection in HCV liver recipients.
Brain Diseases
[Activity of serum arginase in liver cirrhosis. Its special study in the hemorrhagic syndrome and cirrhogenic encephalopathies]
Brain Diseases
[Arginase and experimental hyperammoniemia. II. Action of arginase on experimental portacaval encephalopathy in the dog.]
Brain Diseases, Metabolic
Hyperargininemic Encephalopathy with Unique Clinical Presentation and Novel Genetic Mutations.
Brain Edema
Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema.
Brain Edema
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
Brain Injuries
Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues.
Brain Injuries
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
Brain Injuries
Potential role of fibronectin in microglia/macrophage activation following cryoinjury in the rat brain: An immunohistochemical study.
Brain Injuries, Traumatic
Arginase overexpression in neurons and its effect on traumatic brain injury.
Brain Ischemia
Protective Role of Arginase II in Cerebral Ischemia and Excitotoxicity.
Brain Ischemia
Temporal Gene Expression Profiles after Focal Cerebral Ischemia in Mice.
Brain Neoplasms
Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.
Brain Neoplasms
Roles of nitric oxide and polyamines in brain tumor growth.
Brain Neoplasms
The Gut Microbiota, Kynurenine Pathway, and Immune System Interaction in the Development of Brain Cancer.
Brain Neoplasms
[Comparative study of the activity of arginase isoenzymes in brain tumors of humans and experimental animals]
Breast Neoplasms
A nanobiosensor for the detection of arginase activity.
Breast Neoplasms
Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by N(omega)-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines.
Breast Neoplasms
Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics.
Breast Neoplasms
Antitumor Effect of IP-10 by Using Two Different Approaches: Live Delivery System and Gene Therapy.
Breast Neoplasms
Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells.
Breast Neoplasms
Arginase activity in patients with breast cancer: an analysis of plasma, tumors, and its relationship with the presence of the estrogen receptor.
Breast Neoplasms
Arginase in patients with breast cancer.
Breast Neoplasms
Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade.
Breast Neoplasms
Arginase, a new marker of mammary carcinoma.
Breast Neoplasms
Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment.
Breast Neoplasms
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells.
Breast Neoplasms
Effect of rosuvastatin on arginase enzyme activity and polyamine production in experimental breast cancer.
Breast Neoplasms
Elevated serum arginase activity levels in patients with breast cancer.
Breast Neoplasms
Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients.
Breast Neoplasms
Indicators of L-arginine metabolism in saliva: A focus on breast cancer.
Breast Neoplasms
Key genes and pathways in tumor-educated dendritic cells by bioinformatical analysis.
Breast Neoplasms
L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo.
Breast Neoplasms
Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.
Breast Neoplasms
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase.
Breast Neoplasms
PEGylated recombinant human arginase as a drug for breast cancer.
Breast Neoplasms
Protective role of carnitine in breast cancer via decreasing arginase activity and increasing nitric oxide.
Breast Neoplasms
Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages.
Breast Neoplasms
Proteomic identification of mitochondrial targets of arginase in human breast cancer.
Breast Neoplasms
Simvastatin downregulates HER2 via upregulation of PEA3 to induce cell death in HER2-positive breast cancer cells.
Breast Neoplasms
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer.
Breast Neoplasms
uPAR induces expression of transforming growth factor ? and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.
Breast Neoplasms
[The supernatant of 4T1 breast cancer cell culture increases arginase 1 content in ANA-1 macrophages].
Breast Neoplasms
[Usefulness of postoperative assay of arginase activity in blood serum of women after breast cancer resection]
Bronchopulmonary Dysplasia
An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes.
Bronchopulmonary Dysplasia
Arginase and ?-smooth muscle actin induction after hyperoxic exposure in a mouse model of bronchopulmonary dysplasia.
Bronchopulmonary Dysplasia
Arginase I gene single-nucleotide polymorphism is associated with decreased risk of pulmonary hypertension in bronchopulmonary dysplasia.
Bronchopulmonary Dysplasia
Arginase Inhibition Prevents Bleomycin-Induced Pulmonary Hypertension, Vascular Remodeling and Collagen Deposition in Neonatal Rat Lungs.
Bronchopulmonary Dysplasia
Arginine Therapy for Lung Diseases.
Bronchopulmonary Dysplasia
Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia.
Burkitt Lymphoma
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
carbamoyl-phosphate synthase (ammonia) deficiency
Autosomal recessive inheritance of human mitochondrial carbamyl phosphate synthetase deficiency.
carbamoyl-phosphate synthase (ammonia) deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
carbamoyl-phosphate synthase (ammonia) deficiency
Liver transplantation may prevent neurodevelopmental deterioration in high-risk patients with urea cycle disorders.
carbamoyl-phosphate synthase (ammonia) deficiency
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
carbamoyl-phosphate synthase (ammonia) deficiency
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
Carbamoyl-Phosphate Synthase I Deficiency Disease
Autosomal recessive inheritance of human mitochondrial carbamyl phosphate synthetase deficiency.
Carcinogenesis
6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype.
Carcinogenesis
Arginase activity and nitrogen content in epidermal carcinogenesis in mice.
Carcinogenesis
Arginase and glucose-6-phosphate dehydrogenase activities in spontaneous mammary carcinogenesis.
Carcinogenesis
Determination of arginase activity in tissue homogenates; application to epidermal carcinogenesis in mice.
Carcinogenesis
Human cytomegalovirus may promote tumour progression by upregulating arginase-2.
Carcinogenesis
Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms.
Carcinogenesis
Mapping Arginase Expression with 18F-Fluorinated Late-Generation Arginase Inhibitors Derived from Quaternary ?-Amino Acids.
Carcinogenesis
Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-?1and HES-1 transcripts in 1, 2-dimethylhydrazine-colon carcinogenesis in mice.
Carcinogenesis
Significance of arginase and ornithine in malignant tumors of the human skin.
Carcinogenesis
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer.
Carcinogenesis
The potential therapeutic effect of NG-hydroxy-nor-L-arginine in 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats.
Carcinoma
A preliminary report on the histological and histocytochemical changes in mammary carcinoma in mice after intraperitoneal injections of arginase.
Carcinoma
Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.
Carcinoma
Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells.
Carcinoma
Arginase activity in carcinoma of the gallbladder: a pilot study.
Carcinoma
Arginase activity in prostatic tissue of patients with benign prostatic hyperplasia and prostatic carcinoma.
Carcinoma
Arginase and C-reactive protein as potential serum-based biomarker of head and neck squamous cell carcinoma patients of north east India.
Carcinoma
Arginase and ornithine, as markers in human non-small cell lung carcinoma.
Carcinoma
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
Carcinoma
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
Carcinoma
Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes.
Carcinoma
Arginase, a new marker of mammary carcinoma.
Carcinoma
Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma.
Carcinoma
Arginase-1 is a more sensitive marker than HepPar-1 and AFP in differential diagnosis of hepatocellular carcinoma from nonhepatocellular carcinoma.
Carcinoma
Arginase-1: A novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology.
Carcinoma
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion.
Carcinoma
Arginine uptake and arginase activity in Ehrlich ascites carcinoma cells.
Carcinoma
Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.
Carcinoma
Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.
Carcinoma
BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas.
Carcinoma
Diagnostic Value of Arginase-1 and Glypican-3 in Differential Diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Metastatic Carcinoma of Liver.
Carcinoma
Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Carcinoma
Effect of an alkylating agent on liver arginase in normal and Ehrlich carcinoma bearing mice.
Carcinoma
Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.
Carcinoma
Effects of intraperitoneally injected arginase on growth of mammary carcinoma implants in the mouse.
Carcinoma
Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma.
Carcinoma
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
Carcinoma
Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response.
Carcinoma
Fibrolamellar Carcinoma in the Carney Complex: PRKAR1A Loss Instead of the Classic DNAJB1-PRKACA Fusion.
Carcinoma
Functions of tumor-associated macrophages and macrophages residing in remote anatomical niches in Ehrlich carcinoma bearing mice.
Carcinoma
Hepatic arginase activity in mice bearing Ehrlich ascites carcinoma.
Carcinoma
HepPar-1 and Arginase-1 Immunohistochemistry in Adenocarcinoma of the Small Intestine and Ampullary Region.
Carcinoma
Humoral autoimmune responses to the squamous cell carcinoma antigen protein family in psoriasis.
Carcinoma
In vitro repolarized tumor macrophages inhibit gastric tumor growth.
Carcinoma
Increased number of arginase 1-positive cells in the stroma of carcinomas compared to precursor lesions and nonneoplastic tissues.
Carcinoma
Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma.
Carcinoma
Liposomal CpG-ODN: An in vitro and in vivo study on macrophage subtypes responses, biodistribution and subsequent therapeutic efficacy in mice models of cancers.
Carcinoma
Macrophage polarization in dynamics of Lewis lung carcinoma growth and metastasis.
Carcinoma
Partial purification of a liver-derived tumor cell growth inhibitor that differentially inhibits poorly-liver metastasizing cell lines: identification as an active subunit of arginase.
Carcinoma
Possible implications of arginase and diamine oxidase in prostatic carcinoma.
Carcinoma
Protective role of carnitine in breast cancer via decreasing arginase activity and increasing nitric oxide.
Carcinoma
Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.
Carcinoma
Some aspects of the role of arginine and arginase in mouse carcinoma 63.
Carcinoma
Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology.
Carcinoma
Studies on liver arginase in mice with Ehrlich carcinoma.
Carcinoma
Study of activities of arginase, hexosaminidase, and leucine aminopeptidase in prostate fluid.
Carcinoma
The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1.
Carcinoma
The Diagnostic Value of Arginase-1, FTCD, and MOC-31 Expression in Early Detection of Hepatocellular Carcinoma (HCC) and in Differentiation Between HCC and Metastatic Adenocarcinoma to the Liver.
Carcinoma
The immunoregulatory mechanisms of carcinoma for its survival and development.
Carcinoma
The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
Carcinoma
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Carcinoma
Update on Ancillary Testing in the Evaluation of High-Grade Liver Tumors.
Carcinoma
[Action of arginine and arginase on the Guerin carcinoma.]
Carcinoma
[Significance of arginase-1, glypican-3, hepatocyte paraffin antigen 1 and alpha-fetoprotein in diagnosis and differential diagnosis of liver tumors].
Carcinoma, Ehrlich Tumor
Oxidative stress, polarization of macrophages and tumour angiogenesis: Efficacy of caffeic acid.
Carcinoma, Endometrioid
Uterine Carcinosarcoma with Alpha-Fetoprotein-Producing Hepatoid Component: A Case Report and Literature Review.
Carcinoma, Hepatocellular
A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma.
Carcinoma, Hepatocellular
A phase 1 study of recombinant human arginase 1 (PEG-BCT- 100) in combination with capecitabine and oxaliplatin in advanced hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
A phase II clinical study on the efficacy and predictive biomarker of pegylated recombinant arginase on hepatocellular carcinoma.
Carcinoma, Hepatocellular
A subset of well-differentiated hepatocellular carcinomas are Arginase-1 negative.
Carcinoma, Hepatocellular
Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.
Carcinoma, Hepatocellular
An Engineered Arginase FC Protein Inhibits Tumor Growth In Vitro and In Vivo.
Carcinoma, Hepatocellular
Anti-tumor Efficacy of a Recombinant Human Arginase in Human Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Carcinoma, Hepatocellular
Arginase isoenzymes in human cirrhotic liver.
Carcinoma, Hepatocellular
Arginase-1 and HepPar-1 expression in fine-needle aspiration specimens of primary lung adenocarcinoma.
Carcinoma, Hepatocellular
Arginase-1 and P-glycoprotein are downregulated in canine hepatocellular carcinoma.
Carcinoma, Hepatocellular
Arginase-1 is a more sensitive marker than HepPar-1 and AFP in differential diagnosis of hepatocellular carcinoma from nonhepatocellular carcinoma.
Carcinoma, Hepatocellular
Arginase-1 is a novel immunohistochemical marker of hepatocellular differentiation.
Carcinoma, Hepatocellular
Arginase-1, HepPar-1, and Glypican-3 Are the Most Effective Panel of Markers in Distinguishing Hepatocellular Carcinoma From Metastatic Tumor on Fine-Needle Aspiration Specimens.
Carcinoma, Hepatocellular
Arginase-1: a highly specific marker separating pancreatic adenocarcinoma from hepatocellular carcinoma.
Carcinoma, Hepatocellular
Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.
Carcinoma, Hepatocellular
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
Carcinoma, Hepatocellular
Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.
Carcinoma, Hepatocellular
Blocking the CCL5-CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells.
Carcinoma, Hepatocellular
BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas.
Carcinoma, Hepatocellular
Changes in arginase isoenzymes pattern in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Clinicopathological and prognostic implications of arginase expression in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Cloning of rat liver arginase cDNA and elucidation of regulation of arginase gene expression in H4 rat hepatoma cells.
Carcinoma, Hepatocellular
Comparison of 5 Immunohistochemical Markers of Hepatocellular Differentiation for the Diagnosis of Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Control of expression of the gene for the arginine transporter Cat-1 in rat liver cells by glucocorticoids and insulin.
Carcinoma, Hepatocellular
Diagnostic Value of Arginase-1 and Glypican-3 in Differential Diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Metastatic Carcinoma of Liver.
Carcinoma, Hepatocellular
Establishment of a clonal strain of hepatoma cells derived from Morris hepatoma 8999.
Carcinoma, Hepatocellular
Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas.
Carcinoma, Hepatocellular
Functional and molecular analysis of liver arginase promoter sequences from man and Macaca fascicularis.
Carcinoma, Hepatocellular
Growth inhibitory and arginase activities in liver and hepatoma extracts.
Carcinoma, Hepatocellular
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.
Carcinoma, Hepatocellular
Hepatobiliary pathology.
Carcinoma, Hepatocellular
HepPar-1 and Arginase-1 Immunohistochemistry in Adenocarcinoma of the Small Intestine and Ampullary Region.
Carcinoma, Hepatocellular
Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma.
Carcinoma, Hepatocellular
Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models.
Carcinoma, Hepatocellular
Inhibitory effect of arginine restriction on hepatoma growth.
Carcinoma, Hepatocellular
Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC).
Carcinoma, Hepatocellular
Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion.
Carcinoma, Hepatocellular
Possible contribution of hepatocyte secretion to the elevation of plasma exosomal arginase-1 in high-fat diet-fed mice.
Carcinoma, Hepatocellular
Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.
Carcinoma, Hepatocellular
Prognostic Implications of Arginase and Cytokeratin 19 Expression in Hepatocellular Carcinoma After Curative Hepatectomy: Correlation With Recurrence-Free Survival.
Carcinoma, Hepatocellular
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Carcinoma, Hepatocellular
Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
Carcinoma, Hepatocellular
Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.
Carcinoma, Hepatocellular
Regulation of glucocorticoids of arginase and argininosuccinate synthetase in cultured rat hepatoma cells.
Carcinoma, Hepatocellular
Regulation of urea cycle enzymes in transplantable hepatomas and in the livers of tumor-bearing rats and humans.
Carcinoma, Hepatocellular
Remission of hepatocellular carcinoma with arginine depletion induced by systemic release of endogenous hepatic arginase due to transhepatic arterial embolisation, augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma.
Carcinoma, Hepatocellular
Significance of arginase determination in body fluids of patients with hepatocellular carcinoma and liver cirrhosis before and after surgical treatment.
Carcinoma, Hepatocellular
The delayed glucocorticoid-responsive and hepatoma cell-selective enhancer of the rat arginase gene is located around intron 7.
Carcinoma, Hepatocellular
The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1.
Carcinoma, Hepatocellular
The Diagnostic Value of Arginase-1, FTCD, and MOC-31 Expression in Early Detection of Hepatocellular Carcinoma (HCC) and in Differentiation Between HCC and Metastatic Adenocarcinoma to the Liver.
Carcinoma, Hepatocellular
Update on Ancillary Testing in the Evaluation of High-Grade Liver Tumors.
Carcinoma, Hepatocellular
Well differentiated arginase-1 negative hepatocellular carcinoma.
Carcinoma, Hepatocellular
[Arginase inhibitor nor-NOHA induces apoptosis and inhibits invasion and migration of HepG2 cells].
Carcinoma, Hepatocellular
[Effects of lithium carbonate nanosized particles on nitric oxide production and arginase activity in tumor and peritoneal macrophages in hepatocellular carcinoma 29].
Carcinoma, Hepatocellular
[Role of arginase-1 expression in distinguishing hepatocellular carcinoma from non-hepatocellular tumors].
Carcinoma, Hepatocellular
[Serum arginase activity in patients with liver cirrhosis and hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Significance of arginase-1, glypican-3, hepatocyte paraffin antigen 1 and alpha-fetoprotein in diagnosis and differential diagnosis of liver tumors].
Carcinoma, Hepatocellular
[Study on the clinical significance and correlation of arginase-1 and inducible nitric oxide synthase expression in hepatocellular carcinoma].
Carcinoma, Lewis Lung
Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma.
Carcinoma, Lewis Lung
Macrophage polarization in dynamics of Lewis lung carcinoma growth and metastasis.
Carcinoma, Non-Small-Cell Lung
Arginase and ornithine, as markers in human non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer.
Carcinoma, Renal Cell
Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.
Carcinoma, Renal Cell
Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes.
Carcinoma, Renal Cell
Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma.
Carcinoma, Renal Cell
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion.
Carcinoma, Renal Cell
Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.
Carcinoma, Squamous Cell
Arginase and C-reactive protein as potential serum-based biomarker of head and neck squamous cell carcinoma patients of north east India.
Carcinoma, Squamous Cell
Humoral autoimmune responses to the squamous cell carcinoma antigen protein family in psoriasis.
Carcinoma, Squamous Cell
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Cardiomegaly
Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat.
Cardiomyopathies
Arginase inhibition augments nitric oxide production and facilitates left ventricular systolic function in doxorubicin-induced cardiomyopathy in mice.
Cardiomyopathy, Dilated
Common Variants in the ARG1 Gene Contribute to the Risk of Dilated Cardiomyopathy in the Han Chinese Population.
Cardiovascular Diseases
2-Aminoimidazole Amino Acids as Inhibitors of the Binuclear Manganese Metalloenzyme Human Arginase I.
Cardiovascular Diseases
Alterations in Circulating Amino Acid Metabolite Ratio Associated with Arginase Activity Are Potential Indicators of Metabolic Syndrome: The Korean Genome and Epidemiology Study.
Cardiovascular Diseases
Angiotensin II limits NO production by upregulating arginase through a p38 MAPK-ATF-2 pathway.
Cardiovascular Diseases
Angiotensin II-induced arterial thickening, fibrosis and stiffening involves elevated arginase function.
Cardiovascular Diseases
Angiotensin II-induced Vascular Endothelial Dysfunction through RhoA/Rho Kinase/p38 Mitogen-Activated Protein Kinase/Arginase Pathway.
Cardiovascular Diseases
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.
Cardiovascular Diseases
Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.
Cardiovascular Diseases
Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis.
Cardiovascular Diseases
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Cardiovascular Diseases
Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica.
Cardiovascular Diseases
Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile.
Cardiovascular Diseases
Arginase Inhibition by Ethylacetate Extract of Caesalpinia sappan Lignum Contributes to Activation of Endothelial Nitric Oxide Synthase.
Cardiovascular Diseases
Arginase-1 Variants and the Risk of Familial Coronary Artery Disease in Subjects Originating from Pakistan.
Cardiovascular Diseases
Cyperaceae Species Are Potential Sources of Natural Mammalian Arginase Inhibitors with Positive Effects on Vascular Function.
Cardiovascular Diseases
Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
Cardiovascular Diseases
Effects of lipoprotein-associated phospholipase A2 on arginase/nitric oxide pathway in hemodialysis patients.
Cardiovascular Diseases
Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome.
Cardiovascular Diseases
Functions of arginase isoforms in macrophage inflammatory responses: impact on cardiovascular diseases and metabolic disorders.
Cardiovascular Diseases
Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance.
Cardiovascular Diseases
Human cytomegalovirus induces upregulation of arginase II: possible implications for vasculopathies.
Cardiovascular Diseases
Human-based evidence for the therapeutic potential of arginase inhibitors in cardiovascular diseases.
Cardiovascular Diseases
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Cardiovascular Diseases
Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
Cardiovascular Diseases
Korean red ginseng water extract restores impaired endothelial function by inhibiting arginase activity in aged mice.
Cardiovascular Diseases
Mature Twin Neonates Exhibit Oxidative Stress via Nitric Oxide Synthase Dysfunctionality: A Prognostic Stress Marker in the Red Blood Cells and Umbilical Cord Vessels.
Cardiovascular Diseases
Mechanisms of obesity-induced metabolic and vascular dysfunctions.
Cardiovascular Diseases
Metabolite profiling of arginase inhibitor activity guided fraction of Ficus religiosa leaves by LC-HRMS.
Cardiovascular Diseases
Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats.
Cardiovascular Diseases
Oxidative stress, l-arginine-nitric oxide and arginase pathways in platelets from adolescents with anorexia nervosa.
Cardiovascular Diseases
Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity.
Cardiovascular Diseases
Regulation of arginase pathway in response to wall shear stress.
Cardiovascular Diseases
Small-molecule arginase inhibitors.
Cardiovascular Diseases
Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors.
Cardiovascular Diseases
The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Cardiovascular Diseases
The role of arginase in the microcirculation in cardiovascular disease.
Cardiovascular Diseases
The subcellular compartmentalization of arginine metabolizing enzymes and their role in endothelial dysfunction.
Cardiovascular Diseases
Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus.
Cardiovascular Diseases
ZOOMICS: Comparative Metabolomics of Red Blood Cells From Old World Monkeys and Humans.
Cataract
Urea cycle enzymes in retina, ciliary body-iris, lens and senile cataracts.
Central Nervous System Diseases
Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
Cerebral Palsy
A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
Cerebral Palsy
Arginase Deficiency Presenting as Acute Encephalopathy.
Cerebral Palsy
Arginase deficiency presenting as cerebral palsy.
Cerebral Palsy
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Cerebral Palsy
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Cerebral Palsy
Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.
Cerebral Palsy
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
Cerebral Palsy
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Cerebral Palsy
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Cerebrovascular Disorders
Insights into the Structural Requirements of 2(S)-Amino-6-Boronohexanoic Acid Derivatives as Arginase I Inhibitors: 3D-QSAR, Docking, and Interaction Fingerprint Studies.
Cerebrovascular Disorders
Vascular Arginase Is a Relevant Target to Improve Cerebrovascular Endothelial Dysfunction in Rheumatoid Arthritis: Evidence from the Model of Adjuvant-Induced Arthritis.
Chagas Disease
Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection.
Chagas Disease
Impact of Trypanosoma cruzi infection on nitric oxide synthase and arginase expression and activity in young and elderly mice.
Chagas Disease
Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages.
Chagas Disease
Peripheral blood monocytes show morphological pattern of activation and decreased nitric oxide production during acute Chagas' disease in rats.
Chagas Disease
[Macrophages and arginase induction as a mechanism for parasite escape]
Chemical and Drug Induced Liver Injury
A Performance Evaluation of Three Drug-Induced Liver Injury Biomarkers in the Rat: Alpha-Glutathione S-Transferase, Arginase I, and 4-Hydroxyphenyl-Pyruvate Dioxygenase.
Chemical and Drug Induced Liver Injury
[Effect of Arnica montana tincture on some hydrolytic enzyme activities of rat liver in experimental toxic hepatitis]
Cholangiocarcinoma
Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.
Cholangiocarcinoma
Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms.
Cholangiocarcinoma
BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas.
Cholangiocarcinoma
Budd Chiari Syndrome and Intrahepatic Cholangiocarcinoma, An Unusual Combination: Case Report and Review of the Literature.
Cholangiocarcinoma
Diagnostic Value of Arginase-1 and Glypican-3 in Differential Diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Metastatic Carcinoma of Liver.
Cholangiocarcinoma
Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas.
Cholangiocarcinoma
The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1.
Cholangiocarcinoma
Update on Ancillary Testing in the Evaluation of High-Grade Liver Tumors.
Cholecystitis
Arginase activity in carcinoma of the gallbladder: a pilot study.
Cholecystitis, Acute
[Changes of serum arginase in patients with acute cholecystitis and pancreatitis]
Cholecystitis, Acute
[Serum and liver arginase activity in acute cholecystitis]
Cholestasis
Alterations in selected serum biochemical constituents in equids after induced hepatic disease.
Cholestasis
Effect of L: -arginine on metabolism of polyamines in rat's brain with extrahepatic cholestasis.
Cholestasis
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Cholestasis
Supplementation with L-arginine affects its metabolizing pathways in rat liver subjected to bile duct ligation.
Cholestasis
[Changes in arginase activity in various types of experimental cholestasis]
Chronic Periodontitis
Effectiveness of scaling and root planing versus modified Widman flap on nitric oxide synthase and arginase activity in patients with chronic periodontitis.
Chronic Periodontitis
Periodontal therapy reduces arginase activity in saliva of patients with chronic periodontitis.
Chronic Periodontitis
Salivary arginase in patients with adult periodontitis.
Citrullinemia
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
Citrullinemia
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
Citrullinemia
Clinical and biochemical characteristics of patients with urea cycle disorders in a developing country.
Citrullinemia
Creatine metabolism in patients with urea cycle disorders.
Citrullinemia
Diagnosis and monitoring of inborn errors of metabolism using urease-pretreatment of urine, isotope dilution, and gas chromatography-mass spectrometry.
Citrullinemia
Genetic approach to prenatal diagnosis in urea cycle defects.
Citrullinemia
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Citrullinemia
Liver transplantation may prevent neurodevelopmental deterioration in high-risk patients with urea cycle disorders.
Citrullinemia
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
Citrullinemia
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
Citrullinemia
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
Coinfection
Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation.
Coinfection
Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.
Colitis
Arginase activity in alternatively activated macrophages protects PI3Kp110? deficient mice from dextran sodium sulfate induced intestinal inflammation.
Colitis
Arginase impedes the resolution of colitis by altering the microbiome and metabolome.
Colitis
Cinobufacini Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Inhibiting M1 Macrophage Polarization.
Colitis
Dietary Nondigestible Polysaccharides Ameliorate Colitis by Improving Gut Microbiota and CD4+ Differentiation, as Well as Facilitating M2 Macrophage Polarization.
Colitis
Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice.
Colitis
Inhibition of arginase ameliorates experimental ulcerative colitis in mice.
Colitis
Interleukin-17 induces an atypical M2-like macrophage subpopulation that regulates intestinal inflammation.
Colitis
Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice.
Colitis
Protective role of arginase in a mouse model of colitis.
Colitis, Ulcerative
Inhibition of arginase ameliorates experimental ulcerative colitis in mice.
Colitis, Ulcerative
Small-molecule arginase inhibitors.
Colonic Neoplasms
Activation of autophagy following [HuArgI (Co)-PEG5000]-induced arginine deprivation mediates cell death in colon cancer cells.
Colonic Neoplasms
Arginase activity is inhibited by L-NAME, both in vitro and in vivo.
Colonic Neoplasms
Arginine metabolism in benign and malignant disease of breast and colon: evidence for possible inhibition of tumor-infiltrating macrophages.
Colonic Neoplasms
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
Colonic Neoplasms
Impact of Mycoplasma hyorhinis infection on L-arginine metabolism: differential regulation of the human and murine iNOS gene.
Colonic Neoplasms
Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells.
Colonic Neoplasms
The Redox State of the Glutathione/Glutathione Disulfide Couple Mediates Intracellular Arginase Activation in HCT-116 Colon Cancer Cells.
Colorectal Neoplasms
Arginase as a useful factor for the diagnosis of colorectal cancer liver metastases.
Colorectal Neoplasms
Arginase isoforms in human colorectal cancer.
Colorectal Neoplasms
Clinical significance of arginase in colorectal cancer.
Colorectal Neoplasms
Diagnostic performance of arginase activity in colorectal cancer.
Colorectal Neoplasms
Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines.
Colorectal Neoplasms
HepPar-1 and Arginase-1 Immunohistochemistry in Adenocarcinoma of the Small Intestine and Ampullary Region.
Colorectal Neoplasms
Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion.
Colorectal Neoplasms
l-Arginine as a factor increasing arginase significance in diagnosis of primary and metastatic colorectal cancer.
Colorectal Neoplasms
Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines.
Colorectal Neoplasms
Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells.
Colorectal Neoplasms
Overexpression of Arginase-1 is an indicator of poor prognosis in patients with colorectal cancer.
Colorectal Neoplasms
Proteomic analysis of differentially expressed proteins involving in liver metastasis of human colorectal carcinoma.
Colorectal Neoplasms
Serum arginase activity in postsurgical monitoring of patients with colorectal carcinoma.
Colorectal Neoplasms
[Arginase a marker of cancerogenesis. II. Monitoring of patients after resection of colorectal liver metastases]
Colorectal Neoplasms
[Arginase as a marker of cancerogenesis. I. Monitoring patients after resection of colorectal cancer]
Colorectal Neoplasms
[Arginase as a marker of cancerogenesis. III. Comparison of arginase activity with CEA and Ca 19-9 in liver metastases of colorectal cancer]
Colorectal Neoplasms
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Coma
Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency.
Communicable Diseases
Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors.
Congenital Hypothyroidism
[Arginase deficiency, congenital hypothyroidism and hepatic fibrosis]
Conjunctivitis
[Clinical and biochemical alterations in rats treated with high doses of vitamin A]
Coronary Artery Disease
Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus.
Coronary Artery Disease
Arginase-1 Variants and the Risk of Familial Coronary Artery Disease in Subjects Originating from Pakistan.
Coronary Artery Disease
Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus.
Coronary Artery Disease
Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus.
Coronary Artery Disease
[The role of myeloperoxidase, paraoxonase and nitric oxide system in blood and pericardial fluid in patients with IHD who underwent direct myocardial revascularization.]
Coronary Disease
Arginase type I as a marker of coronary heart disease in hemodialysis patients.
Coronary Disease
Characterization of arginase 1 gene polymorphisms in the Algerian population and association with blood pressure.
COVID-19
Altered amino acid profile in patients with SARS-CoV-2 infection.
COVID-19
Arginase 1 (Arg1) as an Up-Regulated Gene in COVID-19 Patients: A Promising Marker in COVID-19 Immunopathy.
COVID-19
Deciphering the state of immune silence in fatal COVID-19 patients.
COVID-19
Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity.
COVID-19
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells.
COVID-19
Transcriptome and Functions of Granulocytic Myeloid-Derived Suppressor Cells Determine their Association with Disease Severity of COVID-19.
Cross Infection
Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Septic Patients.
Crush Syndrome
[Enzymatic activity in the organism in experimental crush syndrome of the limbs. III. Arginase in kidney and liver, glutaminase in kidney.]
Cystic Fibrosis
Arginase and pulmonary diseases.
Cystic Fibrosis
Arginine Therapy for Lung Diseases.
Cystic Fibrosis
Decreased systemic bioavailability of L-arginine in patients with cystic fibrosis.
Cystic Fibrosis
Increased arginase activity in cystic fibrosis airways.
Cystic Fibrosis
L-ornithine derived polyamines in cystic fibrosis airways.
Cystic Fibrosis
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Cystic Fibrosis
Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1 but not programmed death-ligand 1.
Cystic Fibrosis
ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel.
Cystic Fibrosis
Oscillatory shear stress-induced arginase activity may explain reduced exhaled nitric oxide levels after vest chest physiotherapy in cystic fibrosis.
Cysticercosis
Arginase activity is associated with fibrosis in experimental infection with Taenia crassiceps, but does not play a major role in resistance to infection.
Cysts
Sarcocystis fusiformis: some protein metabolic enzymes in various fractions of sarcocysts of buffalo (Bubalus bubalis).
Cysts
Th2 Immune Responses and Alternatively Activated Macrophages (AAMacs) in Helminth Infection in Aged Mice.
Dacryocystitis
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.
Dehydration
Adaptations of amphibian arginase. I. Response to dehydration.
Dehydration
Effect of drought on polyamine metabolism, yield, protein content and in vitro protein digestibility in tepary (Phaseolus acutifolius) and common (Phaseolus vulgaris) bean seeds
Dementia
Alzheimer's disease as a chronic maladaptive polyamine stress response.
Dementia
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Dementia
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
Demyelinating Diseases
Effect of fasudil on experimental autoimmune neuritis and its mechanisms of action.
Demyelinating Diseases
Myeloid cell plasticity in the evolution of central nervous system autoimmunity.
Dengue
Endothelial nitric oxide pathways in the pathophysiology of dengue: a prospective observational study.
Dermatitis, Atopic
Arginase I levels are decreased in the plasma of pediatric patients with atopic dermatitis.
Dermatitis, Contact
Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity.
Diabetes Complications
Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model.
Diabetes Complications
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Diabetes Mellitus
Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetes.
Diabetes Mellitus
Arginase activity and magnesium levels in blood of children with diabetes mellitus.
Diabetes Mellitus
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Diabetes Mellitus
Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus.
Diabetes Mellitus
Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose-lowering therapy.
Diabetes Mellitus
Arginase inhibition improves microvascular endothelial function in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Assessment of serum arginase I as a type 2 diabetes mellitus diagnosis biomarker in patients.
Diabetes Mellitus
Association of serum arginase I with oxidative stress in a healthy population.
Diabetes Mellitus
Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
Diabetes Mellitus
Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus.
Diabetes Mellitus
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Diabetes Mellitus
Increased levels of circulating arginase I in overweight compared to normal weight adolescents.
Diabetes Mellitus
Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase.
Diabetes Mellitus
Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction.
Diabetes Mellitus
The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes.
Diabetes Mellitus
The Emerging Role of Arginase in Endothelial Dysfunction in Diabetes.
Diabetes Mellitus
Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus.
Diabetes Mellitus, Experimental
Effect of thyroidectomy & alloxan diabetes on rat brain arginase.
Diabetes Mellitus, Experimental
[The activity of arginase in salivary glands of rats with alloxan diabetes]
Diabetes Mellitus, Experimental
[The effect of agmatine on L-arginine metabolism in erythrocytes under streptozotocin-induced diabetes in rats].
Diabetes Mellitus, Type 1
Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans.
Diabetes Mellitus, Type 1
Effect of Arginase-1 Inhibition on the Incidence of Autoimmune Diabetes in NOD Mice.
Diabetes Mellitus, Type 1
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.
Diabetes Mellitus, Type 1
l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice.
Diabetes Mellitus, Type 1
Requisite roles of LOX-1, JNK, and arginase in diabetes-induced endothelial vasodilator dysfunction of porcine coronary arterioles.
Diabetes Mellitus, Type 1
Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus.
Diabetes Mellitus, Type 2
Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction.
Diabetes Mellitus, Type 2
Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose-lowering therapy.
Diabetes Mellitus, Type 2
Arginase inhibition improves microvascular endothelial function in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Assessment of serum arginase I as a type 2 diabetes mellitus diagnosis biomarker in patients.
Diabetes Mellitus, Type 2
Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus.
Diabetes Mellitus, Type 2
Heparin inhibits pro-inflammatory and promotes anti-inflammatory macrophage polarization under hyperglycemic stress.
Diabetes Mellitus, Type 2
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Diabetes Mellitus, Type 2
Insulin reduces plasma arginase activity in type 2 diabetic patients.
Diabetes Mellitus, Type 2
L-Citrulline Supplementation Increases Plasma Nitric Oxide Levels and Reduces Arginase Activity in Patients With Type 2 Diabetes.
Diabetes Mellitus, Type 2
Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase.
Diabetes Mellitus, Type 2
Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species.
Diabetes Mellitus, Type 2
The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes.
Diabetes, Gestational
Increased endothelial inflammation, sTie-2 and arginase activity in umbilical cords obtained from gestational diabetic mothers.
Diabetic Cardiomyopathies
Upregulation of arginase activity contributes to intracellular ROS production induced by high glucose in H9c2 cells.
Diabetic Foot
The role of nitric oxide synthase isoforms and arginase in the pathogenesis of diabetic foot ulcers: possible modulatory effects by transforming growth factor beta 1.
Diabetic Nephropathies
Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism.
Diabetic Nephropathies
Arginase inhibition: a new treatment for preventing progression of established diabetic nephropathy.
Diabetic Nephropathies
Arginase-2 mediates diabetic renal injury.
Diabetic Nephropathies
Xiao-Shen-Formula, a Traditional Chinese Medicine, Improves Glomerular Hyper-Filtration in Diabetic Nephropathy via Inhibiting Arginase Activation and Heparanase Expression.
Diabetic Retinopathy
Arginase as a mediator of diabetic retinopathy.
Diabetic Retinopathy
Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1.
Diabetic Retinopathy
The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes.
Digestive System Diseases
Use of plasma arginase and gamma-glutamyl transpeptidase as specific indicators of heptocellular or hepatobiliary disease in the dog.
Disseminated Intravascular Coagulation
Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho-myeloproliferative disorders and disseminated intravascular coagulation.
Dystonia
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Encephalitis
The inhibitory role of intracellular free zinc in the regulation of Arg-1 expression in interleukin-4-induced activation of M2 microglia.
Encephalomyelitis
Arginase and autoimmune inflammation in the central nervous system.
Encephalomyelitis
Deficient Arginase II Expression without Alteration in Arginase I Expression Attenuated Experimental Autoimmune Encephalomyelitis in Mice.
Encephalomyelitis
Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.
Encephalomyelitis
Metabolic determinants of the immune modulatory function of neural stem cells.
Encephalomyelitis
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Arginase and autoimmune inflammation in the central nervous system.
Encephalomyelitis, Autoimmune, Experimental
Deficient Arginase II Expression without Alteration in Arginase I Expression Attenuated Experimental Autoimmune Encephalomyelitis in Mice.
Encephalomyelitis, Autoimmune, Experimental
Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Metabolic determinants of the immune modulatory function of neural stem cells.
Encephalomyelitis, Autoimmune, Experimental
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
Endometrial Neoplasms
Mapping the immunosuppressive environment in uterine tumors: implications for immunotherapy.
Endometrial Neoplasms
Nitric oxide mediates metabolic coupling of omentum-derived adipose stroma to ovarian and endometrial cancer cells.
Endotoxemia
Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis.
Endotoxemia
Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia.
Endotoxemia
Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia.
Eosinophilia
Arginase inhibition in airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.
Eosinophilia
Arginase inhibition prevents inflammation and remodeling in a Guinea pig model of chronic obstructive pulmonary disease.
Eosinophilia
Broncho-alveolar macrophages express chemokines associated with leukocyte migration in a mouse model of asthma.
Eosinophilia
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.
Eosinophilia
Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.
Eosinophilia
Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus.
Eosinophilia
Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronchopulmonary aspergillosis.
Epilepsy
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Epilepsy
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
Epilepsy
Decreased glutamine synthetase, increased citrulline-nitric oxide cycle activities, and oxidative stress in different regions of brain in epilepsy rat model.
Epilepsy
Manganese and epilepsy: brain glutamine synthetase and liver arginase activities in genetically epilepsy prone and chronically seizured rats.
Erectile Dysfunction
2-Aminoimidazole Amino Acids as Inhibitors of the Binuclear Manganese Metalloenzyme Human Arginase I.
Erectile Dysfunction
Arginase II Deletion Increases Corpora Cavernosa Relaxation in Diabetic Mice.
Erectile Dysfunction
Arginase-boronic acid complex highlights a physiological role in erectile function.
Erectile Dysfunction
Binding of ?,?-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design.
Erectile Dysfunction
Chronic Oral Administration of the Arginase Inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) Improves Erectile Function in Aged Rats.
Erectile Dysfunction
Classical and slow-binding inhibitors of human type II arginase.
Erectile Dysfunction
Expression, purification, and characterization of human type II arginase.
Erectile Dysfunction
Human arginase II: crystal structure and physiological role in male and female sexual arousal.
Erectile Dysfunction
Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction.
Erectile Dysfunction
Influence of arginase polymorphisms and arginase levels/activity on the response to erectile dysfunction therapy with sildenafil.
Erectile Dysfunction
Moringa oleifera leaf and seed inclusive diets influenced the restoration of biochemicals associated with erectile dysfunction in the penile tissue of STZ-induced diabetic male rats treated with/without Acarbose drug.
Erectile Dysfunction
Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation through NOS/cGMP/PKG signalling pathway on exposure to Bisphenol-A in hypertensive rat model.
Erectile Dysfunction
New approaches to the design and discovery of therapies to prevent erectile dysfunction.
Erectile Dysfunction
Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase.
Erectile Dysfunction
p38 Mitogen-Activated Protein Kinase (MAPK) Increases Arginase Activity and Contributes to Endothelial Dysfunction in Corpora Cavernosa from Angiotensin-II-Treated Mice.
Erectile Dysfunction
Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors.
Erectile Dysfunction
Phenolic analysis and erectogenic function of African Walnut (Tetracarpidium conophorum) seeds: The impact of the seed shell on biological activity.
Erectile Dysfunction
Phenolic Extract from Moringa oleifera Leaves Inhibits Key Enzymes Linked to Erectile Dysfunction and Oxidative Stress in Rats' Penile Tissues.
Erectile Dysfunction
Probing the specificity determinants of amino acid recognition by arginase.
Erectile Dysfunction
Relationship between Arginase 1 and Arginase 2 levels and genetic polymorphisms with erectile dysfunction.
Erectile Dysfunction
Serum Arginase II level can be a novel indicator for erectile dysfunction in patients with vasculogenic erectile dysfunction: a comparative study.
Erectile Dysfunction
Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction.
Essential Hypertension
Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension.
Fallopian Tube Neoplasms
Immunosuppressive parameters in serum of ovarian cancer patients change during the disease course.
Fatty Liver
Arginase 1: a potential marker of a common pattern of liver steatosis in HCV and NAFLD children.
Fatty Liver
Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis.
Fatty Liver
Citrulline supplementation attenuates the development of non-alcoholic steatohepatitis in female mice through mechanisms involving intestinal arginase.
Fatty Liver
Macrophage p38? promotes nutritional steatohepatitis through M1 polarization.
Fetal Growth Retardation
Arginase upregulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.
Fibromyalgia
Arginase, NOS activities, and clinical features in fibromyalgia patients.
Fibrosarcoma
Properties of arginase from SV40-induced hamster fibrosarcomas and hamster liver tissues.
Foot Ulcer
The role of nitric oxide synthase isoforms and arginase in the pathogenesis of diabetic foot ulcers: possible modulatory effects by transforming growth factor beta 1.
Gallbladder Neoplasms
Arginase activity in carcinoma of the gallbladder: a pilot study.
Gastritis
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
Gastritis
Arginase-1 and Treg Profile Appear to Modulate Inflammatory Process in Patients with Chronic Gastritis: IL-33 May Be the Alarm Cytokine in H. pylori-Positive Patients.
Gastritis
Helicobacter pylori induces macrophage apoptosis by activation of arginase II.
Gastroenteritis
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
Gastrointestinal Neoplasms
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13.
Genetic Diseases, Inborn
Five novel mutations in ARG1 gene in Chinese patients of argininemia.
Genetic Diseases, Inborn
Liver transplantation prevents progressive neurological impairment in argininemia.
Genetic Diseases, Inborn
Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency.
Genetic Diseases, Inborn
Recurrent hepatic failure and status epilepticus: an uncommon presentation of hyperargininemia.
Genetic Diseases, Inborn
Three novel mutations of ARG1 identified in Chinese patients with argininemia detected by newborn screening.
Giardiasis
Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection.
Gingivitis
Arginine-Nitric Oxide-Polyamine Metabolism in Periodontal Disease.
Glaucoma
Congenital glaucoma associated with an arginase deficit: a case report.
Glioblastoma
Elevated levels of polymorphonuclear myeloid-derived suppressor cells in patients with glioblastoma highly express S100A8/9 and arginase and suppress T cell function.
Glioblastoma
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.
Glioblastoma
Low expressions of ASS1 and OTC in glioblastoma suggest the potential clinical use of recombinant human arginase (rhArg).
Glioblastoma
MicroRNA-613 is downregulated in HCMV-positive glioblastoma and inhibits tumour progression by targeting arginase-2.
Glioblastoma
Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma.
Glioblastoma
uPAR induces expression of transforming growth factor ? and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.
Glioma
A Novel Oral Arginase 1/2 Inhibitor Enhances the Antitumor Effect of PD-1 Inhibition in Murine Experimental Gliomas by Altering the Immunosuppressive Environment.
Glioma
Elevated levels of polymorphonuclear myeloid-derived suppressor cells in patients with glioblastoma highly express S100A8/9 and arginase and suppress T cell function.
Glioma
Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+ exchanger isoform 1.
Glioma
Granulocyte Macrophage-Colony Stimulation Factor Promotes the Immunosuppressive Activity of Glioma-Infiltrating Myeloid Cells through Interleukin-4 Receptor-?
Glioma
Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma.
Glioma
[Comparative study of the activity of arginase isoenzymes in brain tumors of humans and experimental animals]
Glomerulonephritis
Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells.
Glomerulonephritis
Arginase in glomerulonephritis.
Glomerulonephritis
Arginase is a major pathway of L-arginine metabolism in nephritic glomeruli.
Glomerulonephritis
Arginine metabolism in experimental glomerulonephritis: interaction between nitric oxide synthase and arginase.
Glomerulonephritis
Role of Metabolites of Nitric Oxide and Arginase in the Pathogenesis of Glomerulonephritis.
Glucose Intolerance
Assessment of serum arginase I as a type 2 diabetes mellitus diagnosis biomarker in patients.
Glucose Intolerance
Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting.
Graft vs Host Disease
Extracorporeal photochemotherapy induces arginase 1 in patients with graft versus host disease.
Granuloma
Arginase-1 expression in granulomas of tuberculosis patients.
Granuloma
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.
Granuloma
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model.
Granuloma
Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repair.
Granuloma
High gene expression of inflammatory markers and IL-17A correlates with severity of injection site reactions of Atlantic salmon vaccinated with oil-adjuvanted vaccines.
Granuloma
IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages.
Granuloma
IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.
Granuloma
Immunohistological features of visceral leishmaniasis in BALB/c mice.
Granuloma
Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration.
Granuloma
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection.
Granuloma
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis.
Granuloma
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas.
Granuloma
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms.
Granuloma
Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages.
Granuloma
Paracoccidioidomycosis: characterization of subpopulations of macrophages and cytokines in human mucosal lesions.
Granuloma
Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice.
Granuloma
The IL-13/IL-4R? axis is involved in tuberculosis-associated pathology.
Granuloma
TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response.
Graves Disease
Co-expression of inducible nitric oxide synthase and arginases in different human monocyte subsets. Apoptosis regulated by endogenous NO.
guanidinoacetate n-methyltransferase deficiency
Creatine metabolism in patients with urea cycle disorders.
Gyrate Atrophy
Induction of arginase II mRNA by nitric oxide using in vitro model of gyrate atrophy of choroid and retina.
Heart Arrest
Increased arginase levels contribute to impaired perfusion after cardiopulmonary resuscitation.
Heart Defects, Congenital
Derangement of Arginine and Related Amino Acids in Children Undergoing Surgery for Congenital Heart Disease With Cardiopulmonary Bypass.
Heart Diseases
Chronic Co-Administration of Sepiapterin and l-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice.
Heart Failure
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Heart Failure
Arginase inhibition augments nitric oxide production and facilitates left ventricular systolic function in doxorubicin-induced cardiomyopathy in mice.
Heart Failure
Early diagnosis of myocardial infarction by arginase activity determination.
Heart Failure
Increased arginase levels in heart failure represent a therapeutic target to rescue microvascular perfusion.
Heart Failure
Increased inducible nitric oxide synthase and arginase II expression in heart failure: no net nitrite/nitrate production and protein S-nitrosylation.
HELLP Syndrome
Development and validation of GC-MS methods for the comprehensive analysis of amino acids in plasma and urine and applications to the HELLP syndrome and pediatric kidney transplantation: evidence of altered methylation, transamidination, and arginase activity.
Hemangiosarcoma
Immunomodulatory effect of bisphosphonate risedronate sodium on CD163+ arginase 1+ M2 macrophages: the development of a possible supportive therapy for angiosarcoma.
Hematologic Diseases
[Arginase activity in plasma and erythrocytes in children with hematologic diseases]
Hemoglobinopathies
Cysteine-iron promotes arginase activity by driving the Fenton reaction.
Hepatic Encephalopathy
Liver arginase activity in patients with liver cirrhosis and in patients in endogenous hepatic coma.
Hepatic Encephalopathy
[Hepatic arginase activity in patients in hepatic coma.]
Hepatitis
Arginase, a new marker of mammary carcinoma.
Hepatitis
Autoantibody to the liver arginase present in sera of patients with autoimmune hepatitis and chronic hepatitis.
Hepatitis
DETERMINATION OF ARGINASE ACTIVITY IN BLOOD IN EPIDEMIC HEPATITIS.
Hepatitis
Identification of a canine adenovirus (infectious canine hepatitis virus) inhibitor in dog liver extracts as arginase.
Hepatitis
Tumor-induced CD11b(+) Gr-1(+) myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner.
Hepatitis
[Serum arginase activities in acute hepatitis. 3]
Hepatitis
[Significance of determining arginase activity in epidemic hepatitis]
Hepatitis B
Increased levels of arginase in patients with acute hepatitis B suppress antiviral T cells.
Hepatitis C
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis.
Hepatitis C
Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-? Production by Altering Cellular Metabolism via Arginase-1.
Hepatitis C
LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection.
Hepatitis C, Chronic
HCV-Associated Exosomes Upregulate RUNXOR and RUNX1 Expressions to Promote MDSC Expansion and Suppressive Functions through STAT3-miR124 Axis.
Hepatitis, Autoimmune
Anti-CYP2D6 antibodies detected by quantitative radioligand assay and relation to antibodies to liver-specific arginase in patients with autoimmune hepatitis.
Hepatitis, Autoimmune
Autoantibody to the liver arginase present in sera of patients with autoimmune hepatitis and chronic hepatitis.
Hepatitis, Autoimmune
Enzyme immunoassay for autoantibodies to human liver-type arginase and its clinical application.
Hepatitis, Chronic
Autoantibody to the liver arginase present in sera of patients with autoimmune hepatitis and chronic hepatitis.
Hepatitis, Chronic
[Usefulness of determining serum arginase in acute and chronic hepatitis]
Hepatoblastoma
Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.
Herpes Simplex
Amniotic Membrane Induces Peroxisome Proliferator-Activated Receptor-? Positive Alternatively Activated Macrophages.
Herpes Simplex
CCAAT/enhancer-binding protein beta (C/EBP beta) binds and activates while hepatocyte nuclear factor-4 (HNF-4) does not bind but represses the liver-type arginase promoter.
Herpes Simplex
Contribution of macrophage arginase in the intrinsic restriction of herpes simplex virus replication in permissive macrophage cultures induced by gamma-interferon containing products of activated spleen cells.
Herpes Simplex
The significance of the arginine and arginase of tears in experimentally-induced herpes simplex corneae.
Herpes Simplex
[Polyvinylpyrrolidone iodine and arginase: effect on corneal regeneration and its antiviral effect]
HIV Infections
Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.
HIV Infections
Correction: Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection.
HIV Infections
Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study.
Hodgkin Disease
The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin Lymphoma.
Hyperalgesia
Predictive and Preventive Potential of Preoperative Gut Microbiota in Chronic Postoperative Pain in Breast Cancer Survivors.
Hyperalgesia
Treatment with nerve grafts and aFGF attenuates allodynia caused by cervical root transection injuries.
Hyperargininemia
"Cerebral Palsy" in a Patient With Arginase Deficiency.
Hyperargininemia
A case report of neurological complications owing to lately diagnosed hyperargininemia emphasizing the role of national neonatal screening policies in the kingdom of Bahrain.
Hyperargininemia
A long-term survival case of arginase deficiency with severe multicystic white matter and compound mutations.
Hyperargininemia
A new case of arginase deficiency in a Spanish male.
Hyperargininemia
A new French-Canadian family affected by hyperargininaemia.
Hyperargininemia
A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
Hyperargininemia
A novel mutation in ARG1 gene is responsible for arginase deficiency in an Asian family.
Hyperargininemia
A patient with arginase deficiency and episodic hyperammonemia successfully treated with menses cessation.
Hyperargininemia
A simple quantitative micromethod of arginase assay in blood spots dried on filter paper.
Hyperargininemia
A simple screening test for arginase deficiency (hyperargininemia).
Hyperargininemia
A simple spot-test for the detection of erythrocyte arginase deficiency.
Hyperargininemia
A successful trial of enzyme replacement therapy in a case of argininemia.
Hyperargininemia
AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse.
Hyperargininemia
Absence of erythrocyte arginase protein in Japanese patients with hyperargininemia.
Hyperargininemia
Adult-onset arginase deficiency.
Hyperargininemia
Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry.
Hyperargininemia
Analysis of novel ARG1 mutations causing hyperargininemia and correlation with arginase I activity in erythrocytes.
Hyperargininemia
Anesthesia in a patient with arginase deficiency: implications and management.
Hyperargininemia
Anesthetic management of a patient with arginase deficiency undergoing liver transplantation.
Hyperargininemia
Anesthetic management of a pediatric patient with arginase-1 deficiency undergoing strabismus operation: a case report.
Hyperargininemia
Arginase activity in human fibroblast cultures.
Hyperargininemia
Arginase and free amino acids in hyperargininemia: leukocyte arginine as a diagnostic parameter for heterozygotes.
Hyperargininemia
Arginase deficiency and phenylketonuria.
Hyperargininemia
Arginase deficiency in a 12-year-old boy with mild impairment of intellectual function.
Hyperargininemia
Arginase deficiency in Macaca fascicularis. I. Arginase activity and arginine concentration in erythrocytes and liver.
Hyperargininemia
Arginase deficiency in multiple tissues in argininemia.
Hyperargininemia
Arginase deficiency in two brothers.
Hyperargininemia
Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme.
Hyperargininemia
Arginase Deficiency Presenting as Acute Encephalopathy.
Hyperargininemia
Arginase deficiency presenting as cerebral palsy.
Hyperargininemia
Arginase deficiency presenting with cerebral oedema and failure to thrive.
Hyperargininemia
Arginase deficiency presenting with convulsions.
Hyperargininemia
Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema.
Hyperargininemia
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Hyperargininemia
Arginase deficiency.
Hyperargininemia
Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines.
Hyperargininemia
Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris.
Hyperargininemia
Arginase-2 mediates renal ischemia-reperfusion injury.
Hyperargininemia
Arginine to ornithine ratio as a diagnostic marker in patients with positive newborn screening for hyperargininemia.
Hyperargininemia
Argininemia presenting with progressive spastic diplegia.
Hyperargininemia
Argininemia: a treatable genetic cause of progressive spastic diplegia simulating cerebral palsy: case reports and literature review.
Hyperargininemia
Argocytes containing enzyme nanoparticles reduce toxic concentrations of arginine in the blood.
Hyperargininemia
Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl.
Hyperargininemia
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
Hyperargininemia
Biomarkers identified in inborn errors for lysine, arginine, and ornithine.
Hyperargininemia
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
Hyperargininemia
Brain Na+,K(+)-ATPase inhibition induced by arginine administration is prevented by vitamins E and C.
Hyperargininemia
Case series of Arginase 1 deficiency: Expanding the spectrum in hyperargininemia.
Hyperargininemia
Clinical consequences of urea cycle enzyme deficiencies and potential links to arginine and nitric oxide metabolism.
Hyperargininemia
Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency.
Hyperargininemia
Clinical features and neurologic progression of hyperargininemia.
Hyperargininemia
Clinical, biochemical, and molecular spectrum of hyperargininemia due to arginase I deficiency.
Hyperargininemia
Cloning and characterization of the mouse and rat type II arginase genes.
Hyperargininemia
Comparison of arginase activity in red blood cells of lower mammals, primates, and man: evolution to high activity in primates.
Hyperargininemia
Creatine metabolism and the urea cycle.
Hyperargininemia
Creatine metabolism in patients with urea cycle disorders.
Hyperargininemia
Delivery of cytosolic liver arginase into the mitochondrial matrix space: a possible novel site for gene replacement therapy.
Hyperargininemia
Different missense mutations in PDR1 and PDR3 genes from clotrimazole-resistant sake yeast are responsible for pleiotropic drug resistance and improved fermentative activity.
Hyperargininemia
Differential expression of the two human arginase genes in hyperargininemia. Enzymatic, pathologic, and molecular analysis.
Hyperargininemia
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
Hyperargininemia
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
Hyperargininemia
Epilepsia Partialis Continua and Generalized Nonconvulsive Status Epilepticus during the Course of Argininemia: A Report on Two Cases.
Hyperargininemia
Excretion of guanidino-derivates in urine of hyperargininemic patients.
Hyperargininemia
Five novel mutations in ARG1 gene in Chinese patients of argininemia.
Hyperargininemia
Fluorometric micromethod for determination of arginase activity in dried blood spots on filter paper.
Hyperargininemia
Functional consequences of the G235R mutation in liver arginase leading to hyperargininemia.
Hyperargininemia
Genetic approach to prenatal diagnosis in urea cycle defects.
Hyperargininemia
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development.
Hyperargininemia
Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice.
Hyperargininemia
Human hyperargininemia: a mutation not expressed in skin fibroblasts?
Hyperargininemia
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Hyperargininemia
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Hyperargininemia
Hyperargininemia due to liver arginase deficiency.
Hyperargininemia
Hyperargininemia with arginase deficiency.
Hyperargininemia
Hyperargininemia, epilepsy and the metabolism of guanidino compounds.
Hyperargininemia
Hyperargininemia.
Hyperargininemia
Hyperargininemia: a family with a novel mutation in an unexpected site.
Hyperargininemia
Hyperargininemia: the rat as a model for the human disease and the comparative response to enzyme replacement therapy with free arginase and arginase-loaded erythrocytes in vivo.
Hyperargininemia
Hyperargininemic Encephalopathy with Unique Clinical Presentation and Novel Genetic Mutations.
Hyperargininemia
Identification of a novel R21X mutation in the liver-type arginase gene (ARG1) in four Portuguese patients with argininemia.
Hyperargininemia
Identification of mutations (D128G, H141L) in the liver arginase gene of patients with hyperargininemia.
Hyperargininemia
Immunologic studies of arginase in tissues of normal human adult and arginase-deficient patients.
Hyperargininemia
Impaired neurotransmitter amine metabolism in arginase deficiency.
Hyperargininemia
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Hyperargininemia
Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia.
Hyperargininemia
Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism.
Hyperargininemia
Influence of arginase deficiency on amino acid concentrations in sheep erythrocytes with a normal and with a defective transport system for amino acids [proceedings]
Hyperargininemia
Intravenous loading with arginine-hydrochloride and ornithine-aspartate in siblings of two families, presenting a familial neurological syndrome associated with cystinuria.
Hyperargininemia
Isoenzyme pattern and immunological properties of arginase in normal and hyperargininemia fibroblasts.
Hyperargininemia
Isotropic growth of spores and salt tolerance in Aspergillus nidulans
Hyperargininemia
Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice.
Hyperargininemia
Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.
Hyperargininemia
Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse.
Hyperargininemia
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
Hyperargininemia
Liver fibrosis in arginase deficiency.
Hyperargininemia
Liver transplantation prevents progressive neurological impairment in argininemia.
Hyperargininemia
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
Hyperargininemia
Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy.
Hyperargininemia
Loss of function mutations in conserved regions of the human arginase I gene.
Hyperargininemia
Measurement of arginine transport in human erythrocytes using their intrinsic arginase activity: implications for the treatment of familial hyperargininemia.
Hyperargininemia
Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.
Hyperargininemia
Molecular basis of argininemia. Identification of two discrete frame-shift deletions in the liver-type arginase gene.
Hyperargininemia
Molecular basis of hyperargininemia: structure-function consequences of mutations in human liver arginase.
Hyperargininemia
Molecular basis of phenotypic variation in patients with argininemia.
Hyperargininemia
Molecular cloning and nucleotide sequence of cDNA for human liver arginase.
Hyperargininemia
Molecular genetic study of human arginase deficiency.
Hyperargininemia
Mouse model for human arginase deficiency.
Hyperargininemia
Mutations and common variants in the human arginase 1 (ARG1) gene: Impact on patients, diagnostics, and protein structure considerations.
Hyperargininemia
Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice.
Hyperargininemia
Neonatal cholestasis: an uncommon presentation of hyperargininemia.
Hyperargininemia
Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition.
Hyperargininemia
Neurological Deterioration in Three Siblings: Exploring the Spectrum of Argininemia.
Hyperargininemia
Newborn screening for hyperargininemia due to arginase 1 deficiency.
Hyperargininemia
Novel Complex Re-Arrangement of ARG1 commonly shared by unrelated patients with Hyperargininemia.
Hyperargininemia
Novel Homozygous Missense Mutation in the ARG1 Gene in a Large Sudanese Family.
Hyperargininemia
Orotic acid excretion and arginine metabolism.
Hyperargininemia
Polyamine dependence of Chinese hamster ovary cells in serum-free culture is due to deficient arginase activity.
Hyperargininemia
Prenatal diagnosis for arginase deficiency by second-trimester fetal erythrocyte arginase assay and first-trimester ARG1 mutation analysis.
Hyperargininemia
Prenatal diagnosis for arginase deficiency: a case study.
Hyperargininemia
Prenatal diagnosis of the urea cycle diseases: a survey of the European cases.
Hyperargininemia
Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency.
Hyperargininemia
Properties of fetal and adult red blood cell arginase: a possible prenatal diagnostic test for arginase deficiency.
Hyperargininemia
Pteridines and mono-amines: relevance to neurological damage.
Hyperargininemia
Purification, modification, physico-chemical and pharmacokinetic characterization of arginase, an enzyme of potential use in therapy.
Hyperargininemia
Recurrent hepatic failure and status epilepticus: an uncommon presentation of hyperargininemia.
Hyperargininemia
Recurrent unexplained hyperammonemia in an adolescent with arginase deficiency.
Hyperargininemia
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Hyperargininemia
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Hyperargininemia
Review of Multi-Modal Imaging in Urea Cycle Disorders: The Old, the New, the Borrowed, and the Blue.
Hyperargininemia
SCHEMA Designed Variants of Human Arginase I & II Reveal Sequence Elements Important to Stability and Catalysis.
Hyperargininemia
Short-term Correction of Arginase Deficiency in a Neonatal Murine Model With a Helper-dependent Adenoviral Vector.
Hyperargininemia
Spastic gait, intellectual disability and seizures due to a rare mutation causing hyperargininemia.
Hyperargininemia
Strategies to rescue the consequences of inducible arginase-1 deficiency in mice.
Hyperargininemia
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine.
Hyperargininemia
The gene for human liver arginase (ARG1) is assigned to chromosome band 6q23.
Hyperargininemia
The human arginases and arginase deficiency.
Hyperargininemia
The nutritional management of urea cycle disorders.
Hyperargininemia
Three novel mutations in the liver-type arginase gene in three unrelated Japanese patients with argininemia.
Hyperargininemia
Three novel mutations of ARG1 identified in Chinese patients with argininemia detected by newborn screening.
Hyperargininemia
Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring.
Hyperargininemia
Treatment of hyperargininaemia due to arginase deficiency with a chemically defined diet.
Hyperargininemia
Unsuccessful trial of gene replacement in arginase deficiency.
Hyperargininemia
Untargeted metabolomic profiling reveals multiple pathway perturbations and new clinical biomarkers in urea cycle disorders.
Hyperargininemia
Urinary pyrimidine excretion in arginase deficiency.
Hyperargininemia
Use of enzyme-loaded erythrocytes in in-vitro correction of arginase-deficient erythrocytes in familial hyperargininemia.
Hyperargininemia
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
Hyperargininemia
[Advances in clinical and molecular genetics studies on argininemia].
Hyperargininemia
[Arginase deficiency, congenital hypothyroidism and hepatic fibrosis]
Hyperargininemia
[Arginase deficiency]
Hyperargininemia
[Hyperargininemia with arginase deficiency. A new familial metabolic disease. II. Biochemical studies.]
Hyperargininemia
[Hyperargininemia wityh arginase deficiency. A new familial metabolic disease. I. Clinical studies]
Hyperargininemia
[Late diagnosis of congenital argininemia during administration of sodium valproate]
Hyperargininemia
[Proposal for a diet treatment in arginase deficiency]
Hyperargininemia
[Seven patients of argininemia with spastic tetraplegia as the first and major symptom and prenatal diagnosis of two fetuses with high risk].
Hyperargininemia
[The dibasic amino acid metabolic disorders]
Hypercholesterolemia
An Increased Arginase Activity Is Associated with Corpus Cavernosum Impairment Induced by Hypercholesterolemia.
Hypercholesterolemia
Chitosan treatment abrogates hypercholesterolemia-induced erythrocyte's arginase activation.
Hypercholesterolemia
Effect of Two Ginger Varieties on Arginase Activity in Hypercholesterolemic Rats.
Hypercholesterolemia
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Hypercholesterolemia
Inhibition of platelet aggregation by putrescine, spermidine, and spermine in hypercholesterolemic rabbits.
Hypercholesterolemia
Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction: Role of Endothelial Nitric Oxide Synthase and Arginase II.
Hypercholesterolemia
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Hypercholesterolemia
Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase.
Hyperglycemia
Arginase activity and magnesium levels in blood of children with diabetes mellitus.
Hyperglycemia
Insulin reduces plasma arginase activity in type 2 diabetic patients.
Hyperglycemia
Obesity-induced vascular inflammation involves elevated arginase activity.
Hyperglycemia
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-?B Signaling Pathway.
Hyperglycemia
Possible involvement of enhanced arginase activity due to up-regulated arginases and decreased hydroxyarginine in accelerating intimal hyperplasia with hyperglycemia.
Hyperglycemia
Regulation of MAP kinase-mediated endothelial dysfunction in hyperglycemia via arginase I and eNOS dysregulation.
Hyperhomocysteinemia
Nitric oxide bioavailability dysfunction involves in atherosclerosis.
Hyperinsulinism
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Hyperinsulinism
Insulin reduces plasma arginase activity in type 2 diabetic patients.
Hyperlipidemias
Hyperlipidemic versus healthy pancreases: a proteomic analysis using an animal model.
Hyperlysinemias
Periodic hyperammonemia, hyperlysinemia, and homocitrullinuria associated with decreased argininosuccinate synthetase and arginase activities.
Hypersensitivity
Anti-inflammatory Effect of Arginase Inhibitor and Corticosteroid on Airway Allergic Reactions in a Dermatophogoides farinae-induced NC/Nga Mouse Model.
Hypersensitivity
Association of serum arginase I with L-arginine, 3-nitrotyrosine, and exhaled nitric oxide in healthy Japanese workers.
Hypersensitivity
Cyclooxygenase-2 blockade inhibits accumulation and function of myeloid-derived suppressor cells and restores T cell response after traumatic stress.
Hypersensitivity
Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model.
Hypersensitivity
Effect of starvation and refeeding on biochemical and immunological status of Balb/c mice: an experimental model of malnutrition.
Hypersensitivity
Human eosinophil granulocytes do not express the enzyme arginase.
Hypertension
Activation of arginase II by asymmetric dimethylarginine and homocysteine in hypertensive rats induced by hypoxia: a new model of nitric oxide synthesis regulation in hypertensive processes?
Hypertension
Arginase 1 mediates increased blood pressure and contributes to vascular endothelial dysfunction in deoxycorticosterone acetate-salt hypertension.
Hypertension
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Hypertension
Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile.
Hypertension
Arginase inhibition alleviates hypertension associated with diabetes: Effect on endothelial dependent relaxation and NO production.
Hypertension
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Hypertension
Arginase inhibition prevents the development of hypertension and improves insulin resistance in obese rats.
Hypertension
Arginase inhibition protects against hypoxia?induced pulmonary arterial hypertension.
Hypertension
Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension.
Hypertension
Arginase inhibitor attenuates pulmonary artery hypertension induced by hypoxia.
Hypertension
Arginase promotes endothelial dysfunction and hypertension in obese rats.
Hypertension
Arginase promotes skeletal muscle arteriolar endothelial dysfunction in diabetic rats.
Hypertension
Arginase: a critical regulator of nitric oxide synthesis and vascular function.
Hypertension
Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension.
Hypertension
Decreased expression of arginase II in the kidneys of Dahl salt-sensitive rats.
Hypertension
Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
Hypertension
Endothelial dysfunction in hypertension: the role of arginase.
Hypertension
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Hypertension
Experimental studies of OH° radical/pressure dependence of arginase activity using a molecular chromatography approach.
Hypertension
Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice.
Hypertension
Extracts from Almond (Terminalia catappa) leaf and stem bark mitigate the activities of crucial enzymes and oxidative stress associated with hypertension in cyclosporine A-stressed rats.
Hypertension
How could aortic arginase activity enhancement be involved in DOCA-salt hypertension?
Hypertension
HYPOXIC UPREGULATION OF ARGINASE II IN HUMAN LUNG ENDOTHELIAL CELLS.
Hypertension
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Hypertension
Increased arginase activity in aorta of mineralocorticoid-salt hypertensive rats.
Hypertension
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension.
Hypertension
Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling.
Hypertension
L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.
Hypertension
Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats.
Hypertension
Naringin protects against Bisphenol-A induced oculopathy as implication of cataract in hypertensive rat model.
Hypertension
Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation through NOS/cGMP/PKG signalling pathway on exposure to Bisphenol-A in hypertensive rat model.
Hypertension
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
Hypertension
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Hypertension
Oxidative Species Increase Arginase Activity in Endothelial Cells through RhoA/Rho Kinase Pathway.
Hypertension
Peculiarities of a novel bioenzymatic reactor using carbon nanotubes as enzyme activity enhancers: application to arginase.
Hypertension
Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors.
Hypertension
Pulmonary Arterial Hypertension in Rats Due to Age-related Arginase Activation in Intermittent Hypoxia.
Hypertension
Regulation of nitric oxide production in health and disease.
Hypertension
Role of arginase in vessel wall remodeling.
Hypertension
Selective Endothelial Overexpression of Arginase II Induces Endothelial Dysfunction and Hypertension and Enhances Atherosclerosis in Mice.
Hypertension
Time course of vascular arginase expression and activity in spontaneously hypertensive rats.
Hypertension
Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat.
Hypertension
Upregulation of arginase expression and activity in hypertensive rats exposed to chronic intermittent hypobaric hypoxia.
Hypertension
Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles.
Hypertension
Vascular arginase contributes to arteriolar endothelial dysfunction in a rat model of hemorrhagic shock.
Hypertension
Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase.
Hypertension
[Arginase, nitrates, and nitrites in the blood plasma and erythrocytes in hypertension and after therapy with lisinopril and simvastatin].
Hypertension
[Disorders of endothelium-dependent vascular reactions and of the arginase and NO-synthase pathways of L-arginine metabolism in arterial hypertension]
Hypertension
[Effect of irbesartan, an antagonist of AT-1 receptors for angiotensin II, on L-arginine metabolism in arterial hypertension]
Hypertension
[Inhibitors of arginase in the L-arginine metabolic pathway as a new class of antihypertensive drugs: effect of carbamide on lipid oxidative metabolism and on vessel tonus during arterial hypertension]
Hypertension
[Inhibitors of arginase pathway in L-arginine metabolism as a new class of antihypertensive drugs: action of urea on oxidative and nonoxidative metabolism of L-arginine and vascular tone in chronic hypertension]
Hypertension, Pulmonary
An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes.
Hypertension, Pulmonary
Arginase and pulmonary diseases.
Hypertension, Pulmonary
Arginase I gene single-nucleotide polymorphism is associated with decreased risk of pulmonary hypertension in bronchopulmonary dysplasia.
Hypertension, Pulmonary
Arginase Inhibition Prevents Bleomycin-Induced Pulmonary Hypertension, Vascular Remodeling and Collagen Deposition in Neonatal Rat Lungs.
Hypertension, Pulmonary
Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension, and Vascular Stiffness in Transgenic Sickle Cell Mice.
Hypertension, Pulmonary
Arginase Inhibition Reverses Monocrotaline-Induced Pulmonary Hypertension.
Hypertension, Pulmonary
Arginase release following liver reperfusion. Evidence of hemodynamic action of arginase infusions.
Hypertension, Pulmonary
Arginine Therapy for Lung Diseases.
Hypertension, Pulmonary
Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?
Hypertension, Pulmonary
Cervical ganglion block attenuates the progression of pulmonary hypertension via nitric oxide and arginase pathways.
Hypertension, Pulmonary
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
Hypertension, Pulmonary
HIF2?-arginase axis is essential for the development of pulmonary hypertension.
Hypertension, Pulmonary
Hypoxia induces arginase II expression and increases viable human pulmonary artery smooth muscle cell numbers via AMPK?1 signaling.
Hypertension, Pulmonary
Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium.
Hypertension, Pulmonary
HYPOXIC UPREGULATION OF ARGINASE II IN HUMAN LUNG ENDOTHELIAL CELLS.
Hypertension, Pulmonary
In vitro evidence of the inhibitory capacity of chloroquine on arginase activity in sickle erythrocytes.
Hypertension, Pulmonary
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension.
Hypertension, Pulmonary
Intravascular hemolysis and the pathophysiology of sickle cell disease.
Hypertension, Pulmonary
L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells.
Hypertension, Pulmonary
Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia.
Hypertension, Pulmonary
Plasmatic Concentrations of ADMA and Homocystein in Llama (Lama glama) and Regulation of Arginase Type II: An Animal Resistent to the Development of Pulmonary Hypertension Induced by Hypoxia.
Hypertension, Pulmonary
Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling.
Hypertension, Pulmonary
Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.
Hypertension, Pulmonary
Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia.
Hyperthyroidism
Effects of Arginase Inhibition in Hypertensive Hyperthyroid Rats.
Hyperthyroidism
l-Arginine metabolism in cardiovascular and renal tissue from hyper- and hypothyroid rats.
Hyperthyroidism
Regulation of pathways of ornithine metabolism. Effects of thyroid hormone and diabetes on the activity of enzymes at the "ornithine crossroads' in rat liver.
Hyperthyroidism
[Inhibition with ethionine and puromycin of the increase of hepatic arginase and urea excretion in hyperthyroid rats]
Hypertriglyceridemia
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Hypertrophy, Right Ventricular
Arginase inhibition prevents inflammation and remodeling in a Guinea pig model of chronic obstructive pulmonary disease.
Hypoxia-Ischemia, Brain
Changes in arginase isoforms in a murine model of neonatal brain hypoxia-ischemia.
Hypoxia-Ischemia, Brain
The Arginase Pathway in Neonatal Brain Hypoxia-Ischemia.
Idiopathic Pulmonary Fibrosis
Arginase and pulmonary diseases.
Idiopathic Pulmonary Fibrosis
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
Immune System Diseases
Small-molecule arginase inhibitors.
Infarction, Middle Cerebral Artery
Effectiveness of arginase inhibitors against experimentally induced stroke.
Infections
A nanobiosensor for the detection of arginase activity.
Infections
A non-classical type of alveolar macrophage response to Trichinella spiralis infection.
Infections
A potential role for arginase in recurrent infections and hypertrophy of tonsillar and adenoidal tissue.
Infections
A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.
Infections
Aberrant host defense against Leishmania major in the absence of SLPI.
Infections
ADAM10 Partially Protects Mice against Influenza Pneumonia by Suppressing Specific Myeloid Cell Population.
Infections
Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss.
Infections
Alternative strategy for visceral leishmaniosis control: HisAK70-Salmonella Choleraesuis-pulsed dendritic cells.
Infections
Alternatively activated and immunoregulatory monocytes in human filarial infections.
Infections
An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis.
Infections
An overview of the immune response and Arginase I on CHIKV immunopathogenesis.
Infections
Anti-MHV3 state induced by IFN gamma in macrophages is not related to arginine metabolism.
Infections
Arginase 1 activity worsens lung-protective immunity against Streptococcus pneumoniae infection.
Infections
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
Infections
Arginase activity is associated with fibrosis in experimental infection with Taenia crassiceps, but does not play a major role in resistance to infection.
Infections
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo.
Infections
Arginase I induction during Leishmania major infection mediates the development of disease.
Infections
Arginase I induction in macrophages, triggered by Th2-type cytokines, supports the growth of intracellular Leishmania parasites.
Infections
Arginase induction represses gall development during clubroot infection in Arabidopsis.
Infections
Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.
Infections
Arginase modulates Salmonella induced nitric oxide production in RAW264.7 macrophages and is required for Salmonella pathogenesis in mice model of infection.
Infections
Arginase-1 Expression in Myeloid Cells Regulates Staphylococcus aureus Planktonic but Not Biofilm Infection.
Infections
Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection.
Infections
Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris.
Infections
Arginine and immunity.
Infections
Arginine decreases Cryptosporidium parvum infection in undernourished suckling mice involving nitric oxide synthase and arginase.
Infections
Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome.
Infections
Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection.
Infections
Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism.
Infections
Characterisation of arginase paralogues in salmonids and their modulation by immune stimulation/ infection.
Infections
Characterisation of the ex vivo virulence of Leishmania infantum isolates from Phlebotomus perniciosus from an outbreak of human leishmaniosis in Madrid, Spain.
Infections
Correction: MAP Kinase Phosphatase-2 Plays a Key Role in the Control of Infection with Toxoplasma gondii by Modulating iNOS and Arginase-1 Activities in Mice.
Infections
Cruzipain, a major Trypanosoma cruzi antigen, conditions the host immune response in favor of parasite.
Infections
Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages.
Infections
Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Infections
Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma.
Infections
Decidual macrophage M1 polarization contributes to adverse pregnancy induced by Toxoplasma gondii PRU strain infection.
Infections
Diagnosis of Fasciola hepatica infection in beef calves by plasma enzyme analysis.
Infections
Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection.
Infections
Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection.
Infections
Differential liver protein expression during schistosomiasis.
Infections
Differential macrophage polarisation during parasitic infections in common carp (Cyprinus carpio L.).
Infections
Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis.
Infections
Differential regulation of root arginine catabolism and polyamine metabolism in clubroot-susceptible and partially resistant Arabidopsis genotypes.
Infections
Differential Requirements for L-Citrulline and L-Arginine during Antimycobacterial Macrophage Activity.
Infections
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4?+?T cells in response to SIV infections.
Infections
Does placental MDSC-mediated modulation of arginine levels help protect the foetus from auxotrophic pathogens?
Infections
Dual transcriptome analysis reveals differential gene expression modulation influenced by Leishmania arginase and host genetic background.
Infections
Effect of arginase inhibition on pulmonary L-arginine metabolism in murine pseudomonas pneumonia.
Infections
Effect of Neutrophils on Nitric Oxide Production from Stimulated Macrophages.
Infections
Effect of the Mammalian Arginase Inhibitor 2(S)-Amino-6-Boronohexanoic Acid on Bacillus anthracis Arginase.
Infections
Effects of alpha-adrenergic agonists on Toxoplasma gondii replication in human umbilical vein endothelial cells.
Infections
Enhancer-mediated control of macrophage-specific arginase I expression.
Infections
Evaluation of arginase activity, nitric oxide and oxidative stress status in sheep with contagious agalactia.
Infections
Expression of IL-10-triggered STAT3-dependent IL-4R? is required for induction of arginase 1 in visceral leishmaniasis.
Infections
First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones.
Infections
Galectin-3 and Galectin-9 May Differently Regulate the Expressions of Microglial M1/M2 Markers and T Helper 1/Th2 Cytokines in the Brains of Genetically Susceptible C57BL/6 and Resistant BALB/c Mice Following Peroral Infection With Toxoplasma gondii.
Infections
Galectins, Eosinophiles, and Macrophages May Contribute to Schistosoma japonicum Egg-Induced Immunopathology in a Mouse Model.
Infections
Genetic Ablation of Arginase 1 in Macrophages and Neutrophils Enhances Clearance of an Arthritogenic Alphavirus.
Infections
Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice.
Infections
Glycoproteins from sugarcane plants regulate cell polarity of Ustilago scitaminea teliospores.
Infections
Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8(+) T cell responses during acute Friend retrovirus infection.
Infections
HCV-Associated Exosomes Upregulate RUNXOR and RUNX1 Expressions to Promote MDSC Expansion and Suppressive Functions through STAT3-miR124 Axis.
Infections
Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta).
Infections
High dissemination and hepatotoxicity in rats infected with Candida albicans after stress exposure: potential sensitization to liver damage.
Infections
Histopathological and Inflammatory Features of Chronically Discharging Open Mastoid Cavities: Secondary Analysis of a Randomized Clinical Trial.
Infections
Human eosinophil granulocytes do not express the enzyme arginase.
Infections
HYPOXIC UPREGULATION OF ARGINASE II IN HUMAN LUNG ENDOTHELIAL CELLS.
Infections
IL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunction.
Infections
Immunohistological features of visceral leishmaniasis in BALB/c mice.
Infections
Immunonutrition.
Infections
Impact of Mycoplasma hyorhinis infection on L-arginine metabolism: differential regulation of the human and murine iNOS gene.
Infections
Impact of Trypanosoma cruzi infection on nitric oxide synthase and arginase expression and activity in young and elderly mice.
Infections
In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice.
Infections
Increased disease severity of parasite-infected TLR2-/- mice is correlated with decreased central nervous system inflammation and reduced numbers of cells with alternatively activated macrophage phenotypes in a murine model of neurocysticercosis.
Infections
Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages.
Infections
Induction of arginases I and II in cornea during herpes simplex virus infection.
Infections
Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis.
Infections
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.
Infections
Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis.
Infections
Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection.
Infections
Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates.
Infections
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
Infections
Investigation of infectivity of neonates and adults from different rat strains to Toxoplasma gondii Prugniaud shows both variation which correlates with iNOS and Arginase-1 activity and increased susceptibility of neonates to infection.
Infections
Kinetoplastid Membrane Protein-11 as a Vaccine Candidate and a Virulence Factor in Leishmania.
Infections
Kinetoplastid membrane protein-11 exacerbates infection with Leishmania amazonensis in murine macrophages.
Infections
L-Arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis.
Infections
l-Citrulline Metabolism in Mice Augments CD4
Infections
Leishmania (Leishmania) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism.
Infections
Leishmania amazonensis Promastigotes or Extracellular Vesicles Modulate B-1 Cell Activation and Differentiation.
Infections
Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection.
Infections
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Infections
Lysophosphatidylcholine exacerbates Leishmania major-dendritic cell infection through interleukin-10 and a burst in arginase1 and indoleamine 2,3-dioxygenase activities.
Infections
Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.
Infections
Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection.
Infections
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.
Infections
MAP Kinase Phosphatase-2 Plays a Key Role in the Control of Infection with Toxoplasma gondii by Modulating iNOS and Arginase-1 Activities in Mice.
Infections
Metabolomic Profile of BALB/c Macrophages Infected with Leishmania amazonensis: Deciphering L-Arginine Metabolism.
Infections
Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with L. amazonensis.
Infections
MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBP? regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection.
Infections
Mitigating an undesirable immune response of inherent susceptibility to cutaneous leishmaniosis in a mouse model: the role of the pathoantigenic HISA70 DNA vaccine.
Infections
Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulator.
Infections
Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors.
Infections
Mouse strain susceptibility to trypanosome infection: an arginase-dependent effect.
Infections
Multi-Omics Studies Demonstrate Toxoplasma gondii-Induced Metabolic Reprogramming of Murine Dendritic Cells.
Infections
Multitracer stable isotope quantification of arginase and nitric oxide synthase activity in a mouse model of pseudomonas lung infection.
Infections
MyD88-dependent changes in the pulmonary transcriptome after infection with Chlamydia pneumoniae.
Infections
Myeloid-Derived Suppressor Cells Infiltrate the Heart in Acute Trypanosoma cruzi Infection.
Infections
Neutrophils have a protective role during early stages of Leishmania amazonensis infection in BALB/c mice.
Infections
Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients.
Infections
Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study.
Infections
Nitric oxide production is downregulated during respiratory syncytial virus persistence by constitutive expression of arginase 1.
Infections
Overexpression of arginase in Arabidopsis thaliana influences defence responses against Botrytis cinerea.
Infections
Parasite-Derived Arginase Influences Secondary Anti-Leishmania Immunity by Regulating Programmed Cell Death-1-Mediated CD4+ T Cell Exhaustion.
Infections
Programmed death ligand 2 regulates arginase induction and modifies Trypanosoma cruzi survival in macrophages during murine experimental infection.
Infections
Protective role of arginase in a mouse model of colitis.
Infections
Pulmonary infection with an interferon-gamma-producing Cryptococcus neoformans strain results in classical macrophage activation and protection.
Infections
RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages.
Infections
Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype.
Infections
Rat models to investigate host macrophage defense against Trypanosoma cruzi.
Infections
Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection.
Infections
Recombinant IL-4/13A and IL-4/13B induce arginase activity and down-regulate nitric oxide response of primary goldfish (Carassius auratus L.) macrophages.
Infections
Regulation of plant arginase by wounding, jasmonate, and the phytotoxin coronatine.
Infections
Role of l-arginine and CD11b+Gr-1+ cells in immunosuppression induced by Heligmosomoides polygyrus bakeri.
Infections
Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis.
Infections
RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Is Decreased during Simian Immunodeficiency Virus-Associated Central Nervous System Disease.
Infections
Serum gamma glutamyl transpeptidase activity in cattle with induced fascioliasis.
Infections
Signaling pathways that regulate Trypanosoma cruzi infection and immune response.
Infections
Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo.
Infections
Studies on the arginase, 5'-nucleotidase and lysozyme activity by monocytes from visceral leishmaniasis patients.
Infections
Susceptibility of bone marrow derived macrophages to influenza virus infection is dependent on macrophage phenotype.
Infections
Susceptibility to Yersinia pseudotuberculosis infection is linked to the pattern of macrophage activation.
Infections
The absence of TNF permits myeloid Arginase 1 expression in experimental L. monocytogenes infection.
Infections
The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury.
Infections
The first description of complete invertebrate arginine metabolism pathways implies dose-dependent pathogen regulation in Apostichopus japonicus.
Infections
The increase in mannose receptor recycling favors arginase induction and Trypanosoma cruzi survival in macrophages.
Infections
The inhibition of arginase by N(omega)-hydroxy-l-arginine controls the growth of Leishmania inside macrophages.
Infections
The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo.
Infections
Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells.
Infections
Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.
Infections
TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis.
Infections
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Infections
Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages.
Infections
Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.
Infections
Transcriptome of American oysters, Crassostrea virginica, in response to bacterial challenge: insights into potential mechanisms of disease resistance.
Infections
Treatment of Amaranthus cruentus with chemical and biological inducers of resistance has contrasting effects on fitness and protection against compatible Gram positive and Gram negative bacterial pathogens.
Infections
Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog.
Infections
Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c+ Cell Depletion.
Infections
Vagal-?7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection.
Infections
Virulence mechanisms of coccidioides.
Infections
[Expression and Activity of Arginase from Monocytic-type Myeloid-derived Suppressor Cells in Rats Infected with Echinococcus granulosus].
Infections
[Macrophages and arginase induction as a mechanism for parasite escape]
Infections
[Metabolic aspects of hepatic tissue in infection of the mouse from EDP virus. II. Transaminase and arginase activity.]
Infertility
Alterations in Arginase-NO-synthase System of Spermatozoa in Human Subjects with Different Fertility Potential.
Infertility
Seminal arginase activity in infertility.
Inflammatory Bowel Diseases
Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease.
Inflammatory Bowel Diseases
Nitric oxide in inflammatory bowel disease.
Inflammatory Bowel Diseases
Small-molecule arginase inhibitors.
Influenza, Human
Vagal-?7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection.
Insulin Resistance
ADMA elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbid obese humans.
Insulin Resistance
Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation.
Insulin Resistance
Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis.
Insulin Resistance
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Insulin Resistance
Arginase inhibition prevents the development of hypertension and improves insulin resistance in obese rats.
Insulin Resistance
Chronic hyperinsulinemia promotes meta-inflammation and extracellular matrix deposition in adipose tissue: Implications of nitric oxide.
Insulin Resistance
CTLA-4Ig immunotherapy of obesity-induced insulin resistance by manipulation of macrophage polarization in adipose tissues.
Intellectual Disability
A patient with arginase deficiency and episodic hyperammonemia successfully treated with menses cessation.
Intellectual Disability
A successful trial of enzyme replacement therapy in a case of argininemia.
Intellectual Disability
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development.
Intellectual Disability
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Intellectual Disability
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Intestinal Obstruction
Arginine Supplementation Induces Arginase Activity and Inhibits TNF-? Synthesis in Mice Spleen Macrophages After Intestinal Obstruction.
Iron Deficiencies
Current Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck Cancer.
Iron Overload
Pulmonary hypertension in thalassemia.
Irritable Bowel Syndrome
Arginase, NOS activities, and clinical features in fibromyalgia patients.
Ischemic Stroke
Alteration of microRNA 340-5p and Arginase-1 Expression in Peripheral Blood Cells during Acute Ischemic Stroke.
Ischemic Stroke
Effect of stroke on arginase expression and localization in the rat brain.
Ischemic Stroke
Effectiveness of arginase inhibitors against experimentally induced stroke.
Ischemic Stroke
Intravascular hemolysis and the pathophysiology of sickle cell disease.
Ischemic Stroke
The Role of Arginase 1 in Post-Stroke Immunosuppression and Ischemic Stroke Severity.
Keratitis
Induction of arginases I and II in cornea during herpes simplex virus infection.
Keratoconus
Arginase activity, urea, and hydroxyproline concentration are reduced in keratoconus keratocytes.
Keratoconus
[Increased NF-?B and iNOS Expression in Keratoconus Keratocytes - Hints for an Inflammatory Component?]
Kidney Diseases
[Arginase activity of the kidney in some experimental kidney diseases.]
Kidney Failure, Chronic
Effect of chronic renal failure on arginase and argininosuccinate synthetase expression.
Kidney Failure, Chronic
Effect of experimental chronic renal failure upon the production of urea, as measured by the liver arginase activity in rats.
Kidney Failure, Chronic
Erythrocyte nitric oxide metabolism in patients with chronic renal failure.
Kidney Failure, Chronic
Impact of transplantation on neutrophil extracellular trap formation in patients with end-stage renal disease: A single-center, prospective cohort study.
Kidney Failure, Chronic
[Progression of chronic renal failure in remnant rats: role of arginase inhibition]
Kyphosis
Arginine metabolism by macrophages promotes cardiac and muscle fibrosis in mdx muscular dystrophy.
Leg Ulcer
A possible role for inducible arginase isoform (AI) in the pathogenesis of chronic venous leg ulcer.
Leg Ulcer
CORRIGENDUM: A possible role for inducible arginase isoform (AI) in the pathogenesis of chronic venous leg ulcer.
Leg Ulcer
Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous leg ulcers.
Leg Ulcer
Intravascular hemolysis and the pathophysiology of sickle cell disease.
Leiomyoma
Immunohistochemical study of arginase in cancer of the stomach.
Leiomyosarcoma
Immunohistochemical study of arginase in cancer of the stomach.
Leishmaniasis
Age-related alteration of arginase activity impacts on severity of leishmaniasis.
Leishmaniasis
Arginase and its mechanisms in Leishmania persistence.
Leishmaniasis
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo.
Leishmaniasis
Arginase Flavonoid Anti-Leishmanial in Silico Inhibitors Flagged against Anti-Targets.
Leishmaniasis
Arginase I induction during Leishmania major infection mediates the development of disease.
Leishmaniasis
Arginase I induction in macrophages, triggered by Th2-type cytokines, supports the growth of intracellular Leishmania parasites.
Leishmaniasis
Arginase in leishmania.
Leishmaniasis
Biochemical and biophysical properties of a highly active recombinant arginase from Leishmania (Leishmania) amazonensis and subcellular localization of native enzyme.
Leishmaniasis
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections.
Leishmaniasis
Crystal structures of Leishmania mexicana arginase complexed with ?,?-disubstituted boronic amino-acid inhibitors.
Leishmaniasis
Dietary polyphenols rutin, taxifolin and quercetin related compounds target Leishmania amazonensis arginase.
Leishmaniasis
Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis.
Leishmaniasis
Inhibition of Leishmania amazonensis arginase by fucogalactan isolated from Agrocybe aegerita mushroom.
Leishmaniasis
Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection.
Leishmaniasis
L-arginine deprivation impairs Leishmania major-specific T-cell responses.
Leishmaniasis
l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis.
Leishmaniasis
Metabolomic Profile of BALB/c Macrophages Infected with Leishmania amazonensis: Deciphering L-Arginine Metabolism.
Leishmaniasis
Molecular characterization of recombinant arginase of Leishmania donovani.
Leishmaniasis
Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase.
Leishmaniasis
Residue-Specific Message Encoding in CD40-Ligand.
Leishmaniasis
Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis.
Leishmaniasis
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review.
Leishmaniasis
Th1/Th2-regulated arginase availability modulates Leishmania infection.
Leishmaniasis
The inhibition of arginase by N(omega)-hydroxy-l-arginine controls the growth of Leishmania inside macrophages.
Leishmaniasis
The leishmanicidal flavonols quercetin and quercitrin target Leishmania (Leishmania) amazonensis arginase.
Leishmaniasis
The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Leishmaniasis
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis.
Leishmaniasis, Cutaneous
An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis.
Leishmaniasis, Cutaneous
Arginase activity of Leishmania isolated from patients with cutaneous leishmaniasis.
Leishmaniasis, Cutaneous
Arginase I, polyamine, and prostaglandin E2 pathways suppress the inflammatory response and contribute to diffuse cutaneous leishmaniasis.
Leishmaniasis, Cutaneous
Comparing acute and chronic human cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica focusing on arginase activity.
Leishmaniasis, Cutaneous
Differential expression of TLRs 2, 4, 9, iNOS and TNF-? and arginase activity in peripheral blood monocytes from glucantime unresponsive and responsive patients with anthroponotic cutaneous leishmaniasis caused by Leishmania tropica.
Leishmaniasis, Cutaneous
Expression of IL-10-triggered STAT3-dependent IL-4R? is required for induction of arginase 1 in visceral leishmaniasis.
Leishmaniasis, Cutaneous
Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia.
Leishmaniasis, Cutaneous
Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1.
Leishmaniasis, Diffuse Cutaneous
Arginase I, polyamine, and prostaglandin E2 pathways suppress the inflammatory response and contribute to diffuse cutaneous leishmaniasis.
Leishmaniasis, Diffuse Cutaneous
Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis.
Leishmaniasis, Visceral
Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia.
Leishmaniasis, Visceral
Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.
Leishmaniasis, Visceral
Correction: Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection.
Leishmaniasis, Visceral
Expression of IL-10-triggered STAT3-dependent IL-4R? is required for induction of arginase 1 in visceral leishmaniasis.
Leishmaniasis, Visceral
Growth factor and Th2 cytokine signaling pathways converge at STAT6 to promote arginase expression in progressive experimental visceral leishmaniasis.
Leishmaniasis, Visceral
IL-10 and TGF-? Induced Arginase Expression Contributes to Deficient Nitric Oxide Response in Human Visceral Leishmaniasis.
Leishmaniasis, Visceral
Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances.
Leishmaniasis, Visceral
Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression.
Leishmaniasis, Visceral
Studies on the arginase, 5'-nucleotidase and lysozyme activity by monocytes from visceral leishmaniasis patients.
Leprosy
In situ expression of M2 macrophage subpopulation in leprosy skin lesions.
Leprosy
Lymphocyte arginase activity in leprosy--a preliminary report.
Leukemia
Arginase purified from endophytic Pseudomonas aeruginosa IH2: Induce apoptosis through both cell cycle arrest and MMP loss in human leukemic HL-60 cells.
Leukemia
Arginase-mediated "field" defects in AML.
Leukemia
Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.
Leukemia
Cancer therapy with chemically modified enzymes. II. The therapeutic effectiveness of arginase, and arginase modified by the covalent attachment of polyethylene glycol, on the taper liver tumor and the L5178Y murine leukemia.
Leukemia
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
Leukemia
Induction of differentiation of human promyelocytic leukemia cells (HL-60) by arginase.
Leukemia
Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia.
Leukemia, Erythroblastic, Acute
Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines.
Leukemia, Lymphocytic, Chronic, B-Cell
Arginase activity alterations in peripheral blood lymphocytes in the human chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Purification of arginases from human-leukemic lymphocytes and granulocytes: study of their physicochemical and kinetic properties.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Purification of arginases from human-leukemic lymphocytes and granulocytes: study of their physicochemical and kinetic properties.
Leukemia, Myeloid
Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.
Leukemia, Myeloid
Modification by serum of differentiation of cultured human myeloid leukemia cells in response to 12-O-tetradecanoylphorbol-13-acetate.
Leukemia, Myeloid, Acute
Arginase-mediated "field" defects in AML.
Leukemia, Myeloid, Acute
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.
Leukemia, Myeloid, Acute
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells.
Leukemia, Myeloid, Acute
Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
Leukemia, Myelomonocytic, Chronic
Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia.
Leukemia, T-Cell
Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia.
Leukocytosis
Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis.
Leukodystrophy, Globoid Cell
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
Leukodystrophy, Metachromatic
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
Leukostasis
Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.
Leukostasis
Arginase as a mediator of diabetic retinopathy.
Liver Abscess, Amebic
Characteristics of inflammatory reactions during development of liver abscess in hamsters inoculated with Entamoeba nuttalli.
Liver Cirrhosis
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Liver Cirrhosis
Arginase isoenzymes in human cirrhotic liver.
Liver Cirrhosis
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Liver Cirrhosis
Induction of arginase II in livers of bile duct-ligated rats.
Liver Cirrhosis
Liver arginase activity in patients with liver cirrhosis and in patients in endogenous hepatic coma.
Liver Cirrhosis
Liver fibrosis in arginase deficiency.
Liver Cirrhosis
miR-21-regulated M2 polarization of macrophage is involved in arsenicosis-induced hepatic fibrosis through the activation of hepatic stellate cells.
Liver Cirrhosis
Significance of arginase determination in body fluids of patients with hepatocellular carcinoma and liver cirrhosis before and after surgical treatment.
Liver Cirrhosis
[Activity of serum arginase in liver cirrhosis. Its special study in the hemorrhagic syndrome and cirrhogenic encephalopathies]
Liver Cirrhosis
[Serum arginase activity in patients with liver cirrhosis and hepatocellular carcinoma]
Liver Cirrhosis
[Study of ureogenesis in liver cirrhosis by determination of ornithine carbamoyl- transferase and arginase activity in hepatic biopsy specimens]
Liver Diseases
A useful ELISA system for human liver-type arginase, and its utility in diagnosis of liver diseases.
Liver Diseases
Arginase, a new marker of mammary carcinoma.
Liver Diseases
Autoantibody to the liver arginase present in sera of patients with autoimmune hepatitis and chronic hepatitis.
Liver Diseases
Insulin resistance induced by a high-fructose diet potentiates thioacetamide hepatotoxicity.
Liver Diseases
Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity.
Liver Diseases
Neonatal cholestasis: an uncommon presentation of hyperargininemia.
Liver Diseases
Occurrence of cytotoxic autoantibody in rabbits by immunization with heterologous liver arginase: a possible implication in the mechanism of the autoimmune liver diseases.
Liver Diseases
Plasma Arginase-1 Level Is Associated with the Mental Status of Outpatients with Chronic Liver Disease.
Liver Diseases
Significance of arginase determination in body fluids of patients with hepatocellular carcinoma and liver cirrhosis before and after surgical treatment.
Liver Diseases
The effect of thioacetamide on urea cycle enzymes of rat liver.
Liver Diseases
[Arginase activity in cardiopulmonary diseases. Value of its study in statistic liver diseases]
Liver Diseases
[Arginase and carbamyl phosphate synthase activities in chronic liver diseases]
Liver Diseases
[Enzyme determination by radiochemical methods: serum arginase and its clinical use in liver diseases]
Liver Diseases
[EXPLORATION OF ARGINASE ACTIVITY IN THE COURSE OF LIVER DISEASES, TUMORS AND INCLUSIVE.]
Liver Diseases
[Serum arginase activity in patients with liver cirrhosis and hepatocellular carcinoma]
Liver Failure
Recurrent hepatic failure and status epilepticus: an uncommon presentation of hyperargininemia.
Liver Failure
The role of L-arginine in toxic liver failure: interrelation of arginase, polyamine catabolic enzymes and nitric oxide synthase.
Liver Failure, Acute
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Liver Neoplasms
Interactions between interleukin-6 and myeloid-derived suppressor cells drive the chemoresistant phenotype of hepatocellular cancer.
Liver Neoplasms
Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC).
Liver Neoplasms
The significance of arginase-1 expression in the diagnosis of liver cancer: A protocol for a systematic review.
Liver Neoplasms
[Inhibitory effect of ellipticine (dimethyl-5,11-(6H) pyrido (4,3-b) carbazole on the induction of liver cancer by BT6 (N,N-dimethyl-p-(benzothiazolylazo) analine) and its effect on the levels of cytochrome P450 and arginase activity]
Lung Diseases
Arginase and pulmonary diseases.
Lung Diseases
Arginine Therapy for Lung Diseases.
Lung Diseases
Asthma in sickle cell disease.
Lung Diseases
Cell- and isoform-specific increases in arginase expression in acute silica-induced pulmonary inflammation.
Lung Diseases
Increased arginase activity in cystic fibrosis airways.
Lung Diseases
Increased expression of arginase I and II in allergic nasal mucosa.
Lung Diseases
Inhibition of phosphodiesterase 4 amplifies cytokine-dependent induction of arginase in macrophages.
Lung Diseases
L-ornithine derived polyamines in cystic fibrosis airways.
Lung Diseases
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Lung Diseases
Method development and validation for rat serum fingerprinting with CE-MS: application to ventilator-induced-lung-injury study.
Lung Diseases
[Study of arginase activity in alveolar macrophages from patients with lung cancer]
Lung Injury
Arginase Inhibition Prevents Bleomycin-Induced Pulmonary Hypertension, Vascular Remodeling and Collagen Deposition in Neonatal Rat Lungs.
Lung Injury
Induction of arginase isoforms in the lung during hyperoxia.
Lung Injury
Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.
Lung Injury
Nitric Oxide Synthase Activity Correlates with OGG1 in Ozone-Induced Lung Injury Animal Models.
Lung Injury
The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats.
Lung Neoplasms
A potential role for nitric oxide pathway in tuberculous pleural effusion.
Lung Neoplasms
Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression.
Lung Neoplasms
Arginase Pathway Markers of Immune-Microenvironment in Thymic Epithelial Tumors and Small Cell Lung Cancer.
Lung Neoplasms
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion.
Lung Neoplasms
CARD9 prevents lung cancer development by suppressing the expansion of myeloid-derived suppressor cells and IDO production.
Lung Neoplasms
Contactin 1 modulates pegylated arginase resistance in small cell lung cancer through induction of epithelial-mesenchymal transition.
Lung Neoplasms
Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma.
Lung Neoplasms
IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer.
Lung Neoplasms
Key genes and pathways in tumor-educated dendritic cells by bioinformatical analysis.
Lung Neoplasms
LncRNA MALAT1 negatively regulates MDSCs in patients with lung cancer.
Lung Neoplasms
Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.
Lung Neoplasms
Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
Lung Neoplasms
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer.
Lung Neoplasms
Thymosin ?1 promotes the activation of myeloid-derived suppressor cells in a Lewis lung cancer model by upregulating Arginase 1.
Lung Neoplasms
TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host.
Lung Neoplasms
Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I.
Lung Neoplasms
[Study of arginase activity in alveolar macrophages from patients with lung cancer]
Lupus Erythematosus, Systemic
Arginase levels are increased in patients with rheumatoid arthritis.
Lymphoma
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
Lymphoma
Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.
Lymphoma
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
Lymphoma
Tissue enzyme changes in parabiotic rats with subcutaneous lymphoma or fibrosarcoma.
Lymphoma, B-Cell, Marginal Zone
Myeloid-Derived Suppressor Cells and ??T17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice.
Lymphoma, Non-Hodgkin
CD14(+) HLA-DR low/(-) monocytes as indicator of disease aggressiveness in B-cell non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cells.
Lymphopenia
SARS-CoV-2-Induced ARDS Associates with MDSC Expansion, Lymphocyte Dysfunction, and Arginine Shortage.
Malaria
Arginine, nitric oxide, carbon monoxide, and endothelial function in severe malaria.
Malaria
Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.
Malaria
Dimethylarginines: endogenous inhibitors of nitric oxide synthesis in children with falciparum malaria.
Malaria
Host-parasite interactions revealed by Plasmodium falciparum metabolomics.
Malaria
Increased pulmonary pressures and myocardial wall stress in children with severe malaria.
Malaria
Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity.
Malaria
Structural metal dependency of the arginase from the human malaria parasite Plasmodium falciparum.
Malaria, Cerebral
Binding of ?,?-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design.
Malaria, Cerebral
Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Malaria, Cerebral
Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.
Malaria, Cerebral
The activity of Plasmodium falciparum arginase is mediated by a novel inter-monomer salt-bridge between Glu295-Arg404.
Malnutrition
Protein energy malnutrition increases arginase activity in monocytes and macrophages.
Malnutrition
Studies of renal urea cycle enzymes. I. Renal concentrating ability and urea cycle enzymes in the rat during protein deprivation.
Marek Disease
Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.
Melanoma
Alternatively activated macrophage possess antitumor cytotoxicity that is induced by IL-4 and mediated by arginase-1.
Melanoma
An Engineered Arginase FC Protein Inhibits Tumor Growth In Vitro and In Vivo.
Melanoma
Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling.
Melanoma
Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors.
Melanoma
Differential association of CD68+ and CD163+ macrophages with macrophage enzymes, whole tumour gene expression and overall survival in advanced melanoma.
Melanoma
Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy.
Melanoma
Glycyrrhizic acid facilitates anti-tumor immunity by attenuating Tregs and MDSCs: An immunotherapeutic approach.
Melanoma
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.
Melanoma
Liposomal CpG-ODN: An in vitro and in vivo study on macrophage subtypes responses, biodistribution and subsequent therapeutic efficacy in mice models of cancers.
Melanoma
Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma.
Melanoma
Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
Melanoma
Recombinant Human Arginase Inhibits the In vitro and In vivo Proliferation of Human Melanoma by Inducing Cell Cycle Arrest and Apoptosis.
Melanoma
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues.
Melanoma
Role of poly(?-caprolactone) lipid-core nanocapsules on melanoma-neutrophil crosstalk.
Melanoma
Targeting myeloid-derived suppressor cells using a novel adenosine monophosphate-activated protein kinase (AMPK) activator.
Melanoma
The differential contribution of arginase and transamidinase to ornithine biosynthesis in two achromic human melanoma cell lines.
Melanoma, Experimental
Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo.
Melanosis
Arginase-2, a miR-1299 target, enhances pigmentation in melasma by reducing melanosome degradation via senescence-induced autophagy inhibition.
Melioidosis
The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease.
Memory Disorders
Effect of diet supplemented with P. ostreatus and L. subnudus on memory index and key enzymes linked with Alzheimer's disease in streptozotocin-induced diabetes rats.
Memory Disorders
Effects of withdrawal from repeated phencyclidine administration on behavioural function and brain arginine metabolism in rats.
Mesothelioma
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.
Mesothelioma
Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models.
Mesothelioma, Malignant
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.
Metabolic Diseases
A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
Metabolic Diseases
Norvaline Reduces Blood Pressure and Induces Diuresis in Rats with Inherited Stress-Induced Arterial Hypertension.
Metabolic Diseases
[Hyperargininemia with arginase deficiency. A new familial metabolic disease. II. Biochemical studies.]
Metabolic Diseases
[Hyperargininemia wityh arginase deficiency. A new familial metabolic disease. I. Clinical studies]
Metabolic Syndrome
Alterations in Circulating Amino Acid Metabolite Ratio Associated with Arginase Activity Are Potential Indicators of Metabolic Syndrome: The Korean Genome and Epidemiology Study.
Metabolic Syndrome
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Metabolic Syndrome
Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome.
Metabolic Syndrome
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Metabolic Syndrome
Transcriptional changes in blood after aerobic interval training in patients with the metabolic syndrome.
Metabolism, Inborn Errors
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Microcephaly
In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases.
Multiple Myeloma
Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes.
Multiple Sclerosis
Co-expression of inducible nitric oxide synthase and arginases in different human monocyte subsets. Apoptosis regulated by endogenous NO.
Multiple Sclerosis
Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis.
Multiple Sclerosis
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
Multiple Sclerosis
The importance of nitric oxide and arginase in the pathogenesis of acute neuroinflammation: are those contra players with the same direction?
Multiple Sclerosis, Relapsing-Remitting
The importance of nitric oxide and arginase in the pathogenesis of acute neuroinflammation: are those contra players with the same direction?
Muscle Spasticity
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development.
Muscle Spasticity
Metabolite alterations in the genetically spastic mouse.
Muscular Diseases
Classical and slow-binding inhibitors of human type II arginase.
Muscular Diseases
Expression, purification, and characterization of human type II arginase.
Muscular Dystrophies
Arginine metabolism by macrophages promotes cardiac and muscle fibrosis in mdx muscular dystrophy.
Myelodysplastic Syndromes
Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia.
Myelodysplastic Syndromes
[Arginase activity in plasma and erythrocytes in children with hematologic diseases]
Myocardial Infarction
Arginase 1 is upregulated at admission in patients with ST-elevation myocardial infarction.
Myocardial Infarction
Arginase as a target for treatment of myocardial ischemia-reperfusion injury.
Myocardial Infarction
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.
Myocardial Infarction
Association of arginase 1 gene polymorphisms with the risk of myocardial infarction and common carotid intima media thickness.
Myocardial Infarction
Association of rs2781666 G/T polymorphism of arginase I gene with myocardial infarction in Tunisian male population.
Myocardial Infarction
Early diagnosis of myocardial infarction by arginase activity determination.
Myocardial Infarction
Occurrence of arginase in human blood serum in patients with myocardial infarction.
Myocardial Infarction
Serum levels of arginase I are associated with left ventricular function after myocardial infarction.
Myocardial Infarction
[Clinical value of arginase activity determination in human blood serum: diagnosis of myocardial infarction]
Myocardial Infarction
[Usefulness of serum arginase activity determination in the diagnosis of acute myocardial infarct]
Myocardial Ischemia
Coronary microvascular dysfunction in the setting of chronic ischemia is independent of arginase activity.
Myocardial Ischemia
Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury.
Myocarditis
Impact of Trypanosoma cruzi infection on nitric oxide synthase and arginase expression and activity in young and elderly mice.
Nasal Polyps
Comparison of arginase isoform expression in patients with different subtypes of chronic rhinosinusitis.
Neoplasm Metastasis
Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics.
Neoplasm Metastasis
Arginase as a useful factor for the diagnosis of colorectal cancer liver metastases.
Neoplasm Metastasis
Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade.
Neoplasm Metastasis
Complement 5a Enhances Hepatic Metastases of Colon Cancer via Monocyte Chemoattractant Protein-1-Mediated Inflammatory Cell Infiltration.
Neoplasm Metastasis
l-Arginine as a factor increasing arginase significance in diagnosis of primary and metastatic colorectal cancer.
Neoplasm Metastasis
Overexpression of a set of genes, including WISP-1, common to pulmonary metastases of both mouse D122 Lewis lung carcinoma and B16-F10.9 melanoma cell lines.
Neoplasm Metastasis
Potential Co-Relation Between Chronic Periodontitis And Cancer - An Emerging Concept.
Neoplasm Metastasis
Proteomic analysis of differentially expressed proteins involving in liver metastasis of human colorectal carcinoma.
Neoplasm Metastasis
Serum arginase activity in postsurgical monitoring of patients with colorectal carcinoma.
Neoplasm Metastasis
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer.
Neoplasm Metastasis
TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases.
Neoplasm Metastasis
[Arginase a marker of cancerogenesis. II. Monitoring of patients after resection of colorectal liver metastases]
Neoplasm Metastasis
[Arginase as a marker of cancerogenesis. I. Monitoring patients after resection of colorectal cancer]
Neoplasm Metastasis
[Arginase as a marker of cancerogenesis. III. Comparison of arginase activity with CEA and Ca 19-9 in liver metastases of colorectal cancer]
Neoplasm Metastasis
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Neoplasm Metastasis
[Usefulness of postoperative assay of arginase activity in blood serum of women after breast cancer resection]
Neoplasms
1,25?Dihydroxyvitamin D regulates macrophage polarization and ameliorates experimental inflammatory bowel disease by suppressing miR-125b.
Neoplasms
6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype.
Neoplasms
?-Funaltrexamine Displayed Anti-inflammatory and Neuroprotective Effects in Cells and Rat Model of Stroke.
Neoplasms
A bioengineered arginine-depleting enzyme as a long-lasting therapeutic agent against cancer.
Neoplasms
A case of primary carcinosarcoma of the liver with combined hepatocellular carcinoma and cholangiocarcinoma.
Neoplasms
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137).
Neoplasms
A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways.
Neoplasms
A nanobiosensor for the detection of arginase activity.
Neoplasms
A novel and promising therapeutic approach for NSCLC: recombinant human arginase alone or combined with autophagy inhibitor.
Neoplasms
A Study of Arginase Expression in Chronic Non-healing Wounds.
Neoplasms
A subset of well-differentiated hepatocellular carcinomas are Arginase-1 negative.
Neoplasms
Activated macrophages kill tumour cells by releasing arginase.
Neoplasms
Activation of PPAR? in myeloid cells promotes lung cancer progression and metastasis.
Neoplasms
Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype.
Neoplasms
Adoptive transfer of tumor-specific Th2 cells eradicates tumors by triggering an in situ inflammatory immune response.
Neoplasms
Age-associated differences in macrophage response in a vaginal wound healing rat model.
Neoplasms
Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.
Neoplasms
Alteration in IL-1 and arginase activity of tumor-associated macrophages: a role in the promotion of tumor growth.
Neoplasms
Alterations in morphology, arginase, and beta-glucuronidase within a clone of mouse tumor cells in vitro.
Neoplasms
Altered ornithine metabolism in tumor-bearing mice.
Neoplasms
Alternatively activated macrophage possess antitumor cytotoxicity that is induced by IL-4 and mediated by arginase-1.
Neoplasms
Amino Acid Degrading Enzymes and Autophagy in Cancer Therapy.
Neoplasms
An Engineered Arginase FC Protein Inhibits Tumor Growth In Vitro and In Vivo.
Neoplasms
An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway.
Neoplasms
An orthotopic xenograft model with survival hindlimb amputation allows investigation of the effect of tumor microenvironment on sarcoma metastasis.
Neoplasms
Analysis of Macrophage Activation Markers in an Experimental Model of Cutaneous Leishmaniasis Treated with Photodynamic Therapy Mediated by 5-Aminolevulinic Acid.
Neoplasms
Anti-Jagged immunotherapy inhibits MDSCs and overcomes tumor-induced tolerance.
Neoplasms
Anti-tumor Efficacy of a Recombinant Human Arginase in Human Hepatocellular Carcinoma.
Neoplasms
Antitumor Effect of IP-10 by Using Two Different Approaches: Live Delivery System and Gene Therapy.
Neoplasms
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages.
Neoplasms
ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas.
Neoplasms
Arginase 2 and nitric oxide synthase: Pathways associated with the pathogenesis of thyroid tumors.
Neoplasms
Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression.
Neoplasms
Arginase activity determination. A marker of large bowel mucosa proliferation.
Neoplasms
Arginase activity in carcinoma of the gallbladder: a pilot study.
Neoplasms
Arginase activity in nickel sulfide-induced rat tumors.
Neoplasms
Arginase activity in patients with breast cancer: an analysis of plasma, tumors, and its relationship with the presence of the estrogen receptor.
Neoplasms
Arginase activity in prostatic tissue of patients with benign prostatic hyperplasia and prostatic carcinoma.
Neoplasms
Arginase activity is inhibited by L-NAME, both in vitro and in vivo.
Neoplasms
Arginase and ornithine, as markers in human non-small cell lung carcinoma.
Neoplasms
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
Neoplasms
Arginase I levels are decreased in the plasma of pediatric patients with atopic dermatitis.
Neoplasms
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
Neoplasms
Arginase in human urogenital tumors.
Neoplasms
Arginase in patients with breast cancer.
Neoplasms
Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade.
Neoplasms
Arginase pathway in human endothelial cells in pathophysiological conditions.
Neoplasms
Arginase Pathway Markers of Immune-Microenvironment in Thymic Epithelial Tumors and Small Cell Lung Cancer.
Neoplasms
Arginase plays an important role in ammonia detoxification of yellow catfish Pelteobagrus fulvidraco.
Neoplasms
Arginase promotes immune evasion of Echinococcus granulosus in mice.
Neoplasms
Arginase purified from endophytic Pseudomonas aeruginosa IH2: Induce apoptosis through both cell cycle arrest and MMP loss in human leukemic HL-60 cells.
Neoplasms
Arginase Structure and Inhibition: Catalytic Site Plasticity Reveals New Modulation Possibilities.
Neoplasms
Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth.
Neoplasms
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
Neoplasms
Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma.
Neoplasms
Arginase-1 and HepPar-1 expression in fine-needle aspiration specimens of primary lung adenocarcinoma.
Neoplasms
Arginase-1 is a novel immunohistochemical marker of hepatocellular differentiation.
Neoplasms
Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell-mediated inhibition of T-cell proliferation.
Neoplasms
Arginase-1, HepPar-1, and Glypican-3 Are the Most Effective Panel of Markers in Distinguishing Hepatocellular Carcinoma From Metastatic Tumor on Fine-Needle Aspiration Specimens.
Neoplasms
Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope.
Neoplasms
Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms.
Neoplasms
Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling.
Neoplasms
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion.
Neoplasms
Arginase: A Multifaceted Enzyme Important in Health and Disease.
Neoplasms
Arginine and immunity.
Neoplasms
Arginine and nutrition in renal disease.
Neoplasms
Arginine deprivation and tumour cell death: arginase and its inhibition.
Neoplasms
Arginine deprivation in cancer therapy.
Neoplasms
Arginine depriving enzymes: applications as emerging therapeutics in cancer treatment.
Neoplasms
Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy.
Neoplasms
Arginine metabolism in benign and malignant disease of breast and colon: evidence for possible inhibition of tumor-infiltrating macrophages.
Neoplasms
Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors.
Neoplasms
Arginine metabolism: a potential target in pancreatic cancer therapy.
Neoplasms
Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives.
Neoplasms
Arginine Supplementation Induces Arginase Activity and Inhibits TNF-? Synthesis in Mice Spleen Macrophages After Intestinal Obstruction.
Neoplasms
ATF3 promotes migration and M1/M2 polarization of macrophages by activating tenascin?C via Wnt/??catenin pathway.
Neoplasms
Atorvastatin attenuates sympathetic hyperinnervation together with the augmentation of M2 macrophages in rats postmyocardial infarction.
Neoplasms
ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment.
Neoplasms
Autologous reconstitution of human cancer and immune system in vivo.
Neoplasms
Autophagic flux regulates microglial phenotype according to the time of oxygen-glucose deprivation/reperfusion.
Neoplasms
Axitinib, a selective inhibitor of vascular endothelial growth factor receptor, exerts an anticancer effect in melanoma through promoting antitumor immunity.
Neoplasms
Azithromycin alleviates systemic lupus erythematosus via the promotion of M2 polarisation in lupus mice.
Neoplasms
Baicalin ameliorates experimental inflammatory bowel disease through polarization of macrophages to an M2 phenotype.
Neoplasms
Biochemical and molecular aspects of aluminium chloride-induced neurotoxicity in mice and the protective role of Crocus sativus L. extraction and honey syrup.
Neoplasms
Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.
Neoplasms
Blockade of CCL2 enhances immunotherapeutic effect of anti-PD1 in lung cancer.
Neoplasms
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
Neoplasms
Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.
Neoplasms
Blocking the CCL5-CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells.
Neoplasms
Bone marrow macrophage M2 polarization and adipose-derived stem cells osteogenic differentiation synergistically promote rehabilitation of bone damage.
Neoplasms
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.
Neoplasms
Boronic acid-based arginase inhibitors in cancer immunotherapy.
Neoplasms
Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms.
Neoplasms
Calcitonin gene-related peptide exerts anti-inflammatory property through regulating murine macrophages polarization in vitro.
Neoplasms
Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
Neoplasms
Cancer Immune Therapy for Philadelphia Chromosome-Negative Chronic Myeloproliferative Neoplasms.
Neoplasms
Cancer therapy with chemically modified enzymes. II. The therapeutic effectiveness of arginase, and arginase modified by the covalent attachment of polyethylene glycol, on the taper liver tumor and the L5178Y murine leukemia.
Neoplasms
Cancer-promoting mechanisms of tumor-associated neutrophils.
Neoplasms
Cannabinoid CB2 Receptor Mediates Nicotine-Induced Anti-Inflammation in N9 Microglial Cells Exposed to ? Amyloid via Protein Kinase C.
Neoplasms
CARD9 prevents lung cancer development by suppressing the expansion of myeloid-derived suppressor cells and IDO production.
Neoplasms
CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer.
Neoplasms
Cellular and Molecular Pathways Leading to External Root Resorption.
Neoplasms
Characterization of a Wilms' tumor model.
Neoplasms
Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells.
Neoplasms
Characterization of macrophage phenotype, redox, and purinergic response upon chronic treatment with methionine and methionine sulfoxide in mice.
Neoplasms
Characterization of vascular complications in experimental model of fructose-induced metabolic syndrome.
Neoplasms
Chemical modification by polyethylene glycol of the anti-tumor enzyme arginine deiminase from Mycoplasma arginini.
Neoplasms
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.
Neoplasms
Circulating myeloid-derived suppressor cells in patients with pancreatic cancer.
Neoplasms
Cladribine modifies functional properties of microglia.
Neoplasms
Clear cell hepatocellular carcinoma diagnosed by bile duct brushing cytology.
Neoplasms
Clinical Relevance and Suppressive Capacity of Human Myeloid-Derived Suppressor Cell Subsets.
Neoplasms
Clinical significance of arginase in colorectal cancer.
Neoplasms
Comparison of 5 Immunohistochemical Markers of Hepatocellular Differentiation for the Diagnosis of Hepatocellular Carcinoma.
Neoplasms
Complement 5a Enhances Hepatic Metastases of Colon Cancer via Monocyte Chemoattractant Protein-1-Mediated Inflammatory Cell Infiltration.
Neoplasms
Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production.
Neoplasms
Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis.
Neoplasms
Continuous Inhalation Exposure to Fungal Allergen Particulates Induces Lung Inflammation While Reducing Innate Immune Molecule Expression in the Brainstem.
Neoplasms
Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC.
Neoplasms
Correction: Possible Role of Arginase-1 in Concomitant Tumor Immunity.
Neoplasms
Correlation of PPM1A Downregulation with CYP3A4 Repression in the Tumor Liver Tissue of Hepatocellular Carcinoma Patients.
Neoplasms
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer.
Neoplasms
Critical illness induces alternative activation of M2 macrophages in adipose tissue.
Neoplasms
Critical role for arginase 2 in obesity-associated pancreatic cancer.
Neoplasms
Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages.
Neoplasms
Crystal Structures of Complexes with Cobalt-Reconstituted Human Arginase I.
Neoplasms
Current Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck Cancer.
Neoplasms
Decoy Receptor 3 Enhances Tumor Progression via Induction of Tumor-Associated Macrophages.
Neoplasms
Denatonium and Naringenin Promote SCA-9 Tumor Growth and Angiogenesis: Participation of Arginase.
Neoplasms
Deprivation of arginine by recombinant human arginase in prostate cancer cells.
Neoplasms
Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry.
Neoplasms
Diagnostic performance of arginase activity in colorectal cancer.
Neoplasms
Diagnostic Value of Arginase-1 and Glypican-3 in Differential Diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Metastatic Carcinoma of Liver.
Neoplasms
Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity.
Neoplasms
Differences Between Patients with and without Atherosclerosis in Expression Levels of Inflammatory Mediators in the Adipose Tissue Around the Coronary Artery.
Neoplasms
Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines.
Neoplasms
Different muscarinc receptors are involved in the proliferation of murine mammary adenocarcinoma cell lines.
Neoplasms
Differential activation of peritoneal cells by subcutaneous treatment of rats with cryptococcal antigens.
Neoplasms
Differential association of CD68+ and CD163+ macrophages with macrophage enzymes, whole tumour gene expression and overall survival in advanced melanoma.
Neoplasms
Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.
Neoplasms
Differential macrophage polarization in male and female BALB/c mice infected with coxsackievirus B3 defines susceptibility to viral myocarditis.
Neoplasms
Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide.
Neoplasms
Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK.
Neoplasms
Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Neoplasms
Disruption of arginase II alters prostate tumor formation in TRAMP mice.
Neoplasms
Distinct in vivo CD8 and CD4 T cell responses against normal and malignant tissues.
Neoplasms
DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma.
Neoplasms
Docosahexaenoic Acid Improves Diabetic Wound Healing in a Rat Model by Restoring Impaired Plasticity of Macrophage Progenitor Cells.
Neoplasms
Down-regulation of metabolic proteins in hepatocellular carcinoma with portal vein thrombosis.
Neoplasms
Dual biological effects of the cytokines interleukin-10 and interferon-?.
Neoplasms
Ectopic hepatocellular carcinoma mimicking a retroperitoneal tumor: A case report.
Neoplasms
EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer.
Neoplasms
Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.
Neoplasms
Effect of hydrocortisone on arginase activity in ICRC mouse mammary tumours in vitro.
Neoplasms
Effect of Hyperbaric Oxygen Therapy on Polarization Phenotype of Rat Microglia After Traumatic Brain Injury.
Neoplasms
Effect of occupational exposure to aflatoxins on some liver tumor markers in textile workers.
Neoplasms
Effect of rosuvastatin on arginase enzyme activity and polyamine production in experimental breast cancer.
Neoplasms
Effector mechanisms of human monocyte-mediated tumor cytotoxicity in vitro: biochemical, functional, and serological characterization of cytotoxins produced by peripheral blood monocytes isolated by counterflow elutriation.
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Effects of Environmental pH on Macrophage Polarization and Osteoimmunomodulation.
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Effects of female sex steroids on concanavalin A-mediated agglutination of hepatocytes from nonregenerating and regenerating rat liver and hepatic tumor marker enzymes.
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Effects of mitochondrial dysfunction on the immunological properties of microglia.
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Effects of Nanosized Lithium Carbonate Particles on the Functional Activity of Macrophages During Development of Hepatocarcinoma 29.
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Efficacy of expressions of Arg-1, Hep Par-1, and CK19 in the diagnosis of the primary hepatocellular carcinoma subtypes and exclusion of the metastases.
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Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through ?7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.
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Elevated levels of polymorphonuclear myeloid-derived suppressor cells in patients with glioblastoma highly express S100A8/9 and arginase and suppress T cell function.
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Elevated serum arginase activity levels in patients with breast cancer.
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Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma.
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Engineered immune cells as highly sensitive cancer diagnostics.
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Enhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared to their peripheral counterparts.
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Enzyme activities in prostatic carcinoma related to Gleason grades.
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Eplerenone reduced lesion size in early but not advanced atherosclerosis in apolipoprotein E-deficient mice.
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Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination.
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Evaluation of serum arginase activity in benign prostatic hypertrophy and prostatic cancer.
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Ex vivo simulation of leukocyte function: Stimulation of specific subset of leukocytes in whole blood followed by the measurement of function-associated mRNAs.
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Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer.
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Exposure of polyethylene particles induces interferon-? expression in a natural killer T lymphocyte and dendritic cell coculture system in vitro: A preliminary study.
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Expression of arginase by mouse myeloid leukemic cell differentiation in vitro induced with tumor necrosis factor.
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Expression of arginase I in myeloid cells limits control of residual disease after radiation therapy of tumors in mice.
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Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas.
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Expression of immunomodulating genes in prostate cancer and benign prostatic tissue.
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Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients.
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Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.
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Expression, purification, and biochemical properties of arginase from Bacillus subtilis 168.
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Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells.
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Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response.
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Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy.
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Fetal-type gastrointestinal adenocarcinoma: a morphologically distinct entity with unfavourable prognosis.
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Fibrolamellar Carcinoma in the Carney Complex: PRKAR1A Loss Instead of the Classic DNAJB1-PRKACA Fusion.
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Frequent adaptive immune responses against arginase-1.
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Functional heterogeneity among peritoneal macrophages. III. No evidence for the role of arginase in the inhibition of tumor cell growth by supernatants from macrophages or macrophage subpopulation cultures.
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Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
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Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGF?1-induced macrophages.
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Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice.
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Granulocyte functions are independent of arginine availability.
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Gypenoside Attenuates ? Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling.
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Hepatic Stellate Cells Enhance Liver Cancer Progression by Inducing Myeloid-Derived Suppressor Cells through Interleukin-6 Signaling.
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Hepatocellular carcinoma with neuroendocrine differentiation: a case report.
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Hepatoid Teratoma, Hepatoid Yolk Sac Tumor, and Hepatocellular Carcinoma: A Morphologic and Immunohistochemical Study of 30 Cases.
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HIF-1? regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment.
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High dose gabapentin does not alter tumor growth in mice but reduces arginase activity and increases superoxide dismutase, IL-6 and MCP-1 levels in Ehrlich ascites.
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High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
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Histological and biochemical investigation of the renoprotective effects of metformin in diabetic and prostate cancer model.
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Human cytomegalovirus may promote tumour progression by upregulating arginase-2.
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Human eosinophil granulocytes do not express the enzyme arginase.
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Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models.
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Human splenic myeloid derived suppressor cells: Phenotypic and clustering analysis.
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Hypolipidemic drug clofibrate induces hepatic dedifferentiation.
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HYPOXIC UPREGULATION OF ARGINASE II IN HUMAN LUNG ENDOTHELIAL CELLS.
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Identification and characterization of B220+/B220- subpopulations in murine Gr1+CD11b+ cells during tumorigenesis.
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Identifying Factors of Microparticles Modified with Arginine Derivatives That Induce Phenotypic Shifts in Macrophages.
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IL-4R? aptamer-liposome-CpG oligodeoxynucleotides suppress tumour growth by targeting the tumour microenvironment.
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Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome.
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Immunocompetence of macrophages in rats exposed to Candida albicans infection and stress.
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Immunohistochemical study of arginase in cancer of the stomach.
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Immunosuppressive effects and mechanisms of three myeloid-derived suppressor cells subsets including monocytic-myeloid-derived suppressor cells, granulocytic-myeloid-derived suppressor cells, and immature-myeloid-derived suppressor cells.
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Immunosuppressive Immature Myeloid Cell Generation Is Controlled by Glutamine Metabolism in Human Cancer.
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Immunosuppressive parameters in serum of ovarian cancer patients change during the disease course.
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Immunotherapy: Beyond Anti-PD-1 and Anti-PD-L1 Therapies.
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Impact of Marine-Based Biomaterials on the Immunoregulatory Properties of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Use of Fish Collagen in Bone Tissue Engineering.
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Impact of substrate protonation and tautomerization States on interactions with the active site of arginase I.
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Impacts of replacement of dietary fish oil by vegetable oils on growth performance, anti-oxidative capacity, and inflammatory response in large yellow croaker Larimichthys crocea.
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In situ hybridisation for albumin RNA in paediatric liver cancers compared with common immunohistochemical markers.
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In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells.
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Increase in frequency of myeloid-derived suppressor cells in mice with spontaneous pancreatic carcinoma.
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Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms.
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Increased levels of circulating arginase I in overweight compared to normal weight adolescents.
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Indoleamine 2,3-Dioxygenase Regulates Macrophage Recruitment, Polarization and Phagocytosis in Aspergillus Fumigatus Keratitis.
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Induction of arginase II in human Caco-2 tumor cells by cyclic AMP.
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Inflammatory and biocompatibility evaluation of antimicrobial peptide GL13K immobilized onto titanium by silanization.
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Influence of hormonal status on arginase activity in mammary tissue and tumour.
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Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes.
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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
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Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma.
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Inhibition of curcumin on myeloid-derived suppressor cells is requisite for controlling lung cancer.
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Inhibition of KCa3.1 Channels Suppresses Atrial Fibrillation via the Attenuation of Macrophage Pro-inflammatory Polarization in a Canine Model With Prolonged Rapid Atrial Pacing.
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Inhibition of vacuolar ATPase subunit in tumor cells delays tumor growth by decreasing the essential macrophage population in the tumor microenvironment.
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Inhibitory effect of arginine restriction on hepatoma growth.
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Inhibitory effect of mycoplasma-released arginase. Activity in mixed-lymphocyte and tumour cell cultures.
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Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis.
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Integrin CD11b Deficiency Aggravates Retinal Microglial Activation and RGCs Degeneration After Acute Optic Nerve Injury.
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Interferon-gamma-induced nitric oxide inhibits the proliferation of murine renal cell carcinoma cells.
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Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis.
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Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury.
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Interleukin-4 Expressed By Neoplastic Cells Provokes an Anti-Metastatic Myeloid Immune Response.
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Intracellular sources of ornithine for polyamine synthesis in endothelial cells.
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Investigating the Synergistic Effects of Combined Modified Alginates on Macrophage Phenotype.
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Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.
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Isolation and screening of extracellular anticancer enzymes from halophilic and halotolerant bacteria from different saline environments in Iran.
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Key genes and pathways in tumor-educated dendritic cells by bioinformatical analysis.
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L-arginine availability regulates T-lymphocyte cell-cycle progression.
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l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells.
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Lack of effect of high potency arginase on tumor growth.
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Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a d-galactose-induced accelerated aging mouse model.
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Lactobacillus rhamnosus GG promotes M1 polarization in murine bone marrow-derived macrophages by activating TLR2/MyD88/MAPK signaling pathway.
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Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype.
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Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
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Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity With Poor Prognosis and Review of the Literature.
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Liver metastatic basaloid squamous cell carcinoma with negative expression of pancytokeratin: a case report and literature review.
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Luteolin transforms the polarity of bone marrow-derived macrophages to regulate the cytokine storm.
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Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.
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Macrophage arginine metabolism and the inhibition or stimulation of cancer.
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Macrophage Depletion Improves Chronic Rejection in Rats With Allograft Heart Transplantation.
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Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis.
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Macrophage-Derived IL1? and TNF? Regulate Arginine Metabolism in Neuroblastoma.
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Macrophages from irradiated tumors express higher levels of iNOS, arginase-I and COX-2, and promote tumor growth.
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Macrophages - a perspective target for antineoplastic immunotherapy.
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Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells.
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Mapping the immunosuppressive environment in uterine tumors: implications for immunotherapy.
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Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
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Mesenchymal stem cells induce the ramification of microglia via the small RhoGTPases Cdc42 and Rac1.
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Mesenchymal stem cells rescue acute hepatic failure by polarizing M2 macrophages.
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Metabolic pathways of L-arginine and therapeutic consequences in tumors.
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Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives.
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Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo.
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Microenvironmental arginine depletion by macrophages in vivo.
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MicroRNA-155 inversely correlates with esophageal cancer progression through regulating tumor-associated macrophage FGF2 expression.
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MicroRNA-613 is downregulated in HCMV-positive glioblastoma and inhibits tumour progression by targeting arginase-2.
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Mitochondrial arginase-2 is a cell?autonomous regulator of CD8+ T cell function and antitumor efficacy.
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Molecular basis and current strategies of therapeutic arginine depletion for cancer.
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Molecular genetics of ornithine decarboxylase in human tumor cells.
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Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-?B and signal transducer and activator of transcription 3 pathways.
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Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma.
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Myeloid Cell-Derived Arginase in Cancer Immune Response.
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Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy.
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Myeloid-derived suppressor cells in mammary tumor progression in FVB Neu transgenic mice.
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Myeloid-Derived Suppressor Cells Specifically Suppress IFN-? Production and Antitumor Cytotoxic Activity of V?2 T Cells.
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Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity.
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Neuroblastoma formation requires unconventional CD4 T cells and Arginase-1-dependent myeloid cells.
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Neurotoxicity of soluble macrophage products in vitro--influence of dexamethasone.
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Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.
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Newly available antibodies with practical applications in surgical pathology.
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NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
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Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme.
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Nitric oxide mediates metabolic coupling of omentum-derived adipose stroma to ovarian and endometrial cancer cells.
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Nitric oxide, apoptosis and macrophage polarization during tumor progression.
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NMAAP1 Expressed in BCG-Activated Macrophage Promotes M1 Macrophage Polarization.
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells.
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Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.
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Novel Arginase Inhibitors for Treating Cancer and Respiratory Inflammatory Diseases.
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Obesity-induced vascular inflammation involves elevated arginase activity.
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Occurrence of isoenzymes of arginase in mouse lung tumour.
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Opposing roles for complement component c5a in tumor progression and the tumor microenvironment.
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Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPAR? and NF-?B pathways.
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Ovarian Sertoli-Leydig Cell Tumor With Heterologous Hepatocytes and a Hepatocellular Carcinomatous Element.
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Overexpression of a set of genes, including WISP-1, common to pulmonary metastases of both mouse D122 Lewis lung carcinoma and B16-F10.9 melanoma cell lines.
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Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells.
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Oxidative stress, polarization of macrophages and tumour angiogenesis: Efficacy of caffeic acid.
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Partial purification of a liver-derived tumor cell growth inhibitor that differentially inhibits poorly-liver metastasizing cell lines: identification as an active subunit of arginase.
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Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata.
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Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC).
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Pegylated Recombinant Human Arginase 1 Induces Autophagy and Apoptosis via the ROS-Activated AKT/mTOR Pathway in Bladder Cancer Cells.
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PGC-1?-Mediated Mitochondrial Biogenesis is Involved in Cannabinoid Receptor 2 Agonist AM1241-Induced Microglial Phenotype Amelioration.
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Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors.
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Pharmacological hypothermia induced neurovascular protection after severe stroke of transient middle cerebral artery occlusion in mice.
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Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function.
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Physalis angulata Calyces Modulate Macrophage Polarization and Alleviate Chemically Induced Intestinal Inflammation in Mice.
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Physicochemical properties of liposomal modifiers that shift macrophage phenotype.
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Plasma arginase concentration measured by an enzyme-linked immunosorbent assay (ELISA) in normal adult population.
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Possible implications of arginase and diamine oxidase in prostatic carcinoma.
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Possible role of arginase-1 in concomitant tumor immunity.
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Potential Co-Relation Between Chronic Periodontitis And Cancer - An Emerging Concept.
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Preconditioning Human Adipose-Derived Stromal Cells on Decellularized Adipose Tissue Scaffolds Within a Perfusion Bioreactor Modulates Cell Phenotype and Promotes a Pro-regenerative Host Response.
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Primary Hepatoid Carcinoma of the Pancreas: A Clinicopathological Study of 3 Cases With Review of Additional 31 Cases in the Literature.
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Probiotics protect mice from CoCrMo particles-induced osteolysis.
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Prognostic Implications of Arginase and Cytokeratin 19 Expression in Hepatocellular Carcinoma After Curative Hepatectomy: Correlation With Recurrence-Free Survival.
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Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection.
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Proliferative actions of muscarinic receptors expressed in macrophages derived from normal and tumor bearing mice.
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Promotion of Primary Murine Breast Cancer Growth and Metastasis by Adipose-Derived Stem Cells Is Reduced in the Presence of Autologous Fat Graft.
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Properties of partially purified arginase from mouse lung tumour.
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Properties of arginase immobilized in a fibrin clot.
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Prorenin stimulates a pro-angiogenic and pro-inflammatory response in retinal endothelial cells and an m1 phenotype in retinal microglia.
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Protective effects of GPR120 agonist-programmed macrophages on renal interstitial fibrosis in unilateral ureteral obstruction (UUO) rats.
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Protective role of carnitine in breast cancer via decreasing arginase activity and increasing nitric oxide.
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Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages.
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Proteomic analysis of differentially expressed proteins involving in liver metastasis of human colorectal carcinoma.
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Pten null prostate epithelium promotes localized MDSC expansion and immune suppression during tumor initiation and progression.
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Purification and immobilization of L-arginase from thermotolerant Penicillium chrysogenum KJ185377.1; with unique kinetic properties as thermostable anticancer enzyme.
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Purification, modification, physico-chemical and pharmacokinetic characterization of arginase, an enzyme of potential use in therapy.
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Rational design, engineer, and characterization of a novel pegylated single isomer human arginase for arginine depriving anti-cancer treatment.
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Real-time gene expression analysis in carp (Cyprinus carpio L.) skin: inflammatory responses caused by the ectoparasite Ichthyophthirius multifiliis.
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Recombinant Bacillus caldovelox Arginase Mutant (BCA-M) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Human Cervical Cancer Cells.
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Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
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Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cells.
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Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
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Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.
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Recombinant human arginase toxicity in mice is reduced by citrulline supplementation.
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Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells.
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Regulation of macrophage arginase expression and tumor growth by the ron receptor tyrosine kinase.
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Remission of hepatocellular carcinoma with arginine depletion induced by systemic release of endogenous hepatic arginase due to transhepatic arterial embolisation, augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma.
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Replacing Mn(2+) with Co(2+) in human arginase i enhances cytotoxicity toward l-arginine auxotrophic cancer cell lines.
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Research of novel anticancer agents targeting arginase inhibition.
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Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.
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Resolution mediator chemerin15 reprograms the wound microenvironment to promote repair and reduce scarring.
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Rg3-enriched Korean Red Ginseng extract inhibits blood-brain barrier disruption in an animal model of multiple sclerosis by modulating expression of NADPH oxidase 2 and 4.
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rIFN-gamma-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibition.
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Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma.
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Role of non-neuronal cholinergic system in breast cancer progression.
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Role of OGR1 in myeloid-derived cells in prostate cancer.
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Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors.
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Salvianolic acid B exerts vasoprotective effects through the modulation of heme oxygenase-1 and arginase activities.
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Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation.
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SCHEMA Designed Variants of Human Arginase I & II Reveal Sequence Elements Important to Stability and Catalysis.
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Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo.
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Serum arginase activity in postsurgical monitoring of patients with colorectal carcinoma.
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Significance of arginase and ornithine in malignant tumors of the human skin.
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Silicone Implants Immobilized with Interleukin-4 Promote the M2 Polarization of Macrophages and Inhibit the Formation of Fibrous Capsules.
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Silymarin suppressed lung cancer growth in mice via inhibiting myeloid-derived suppressor cells.
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Single amino acid arginine starvation efficiently sensitizes cancer cells to canavanine treatment and irradiation.
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Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.
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Small-molecule arginase inhibitors.
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Soluble factors differ in platelets derived from separate niches: a pilot study comparing the secretome of peripheral blood and bone marrow platelets.
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Some new approaches to potential test systems for drugs against prostatic cancer.
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Spared Nerve Injury Increases the Expression of Microglia M1 Markers in the Prefrontal Cortex of Rats and Provokes Depression-Like Behaviors.
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Spontaneous T-cell responses against Arginase-1 in the chronic myeloproliferative neoplasms relative to disease stage and type of driver mutation.
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ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses.
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Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy.
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Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
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Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology.
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Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity.
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Suppression of T-cell functions by human granulocyte arginase.
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Suppression of T-cell responses by tumor metabolites.
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Synergistic effects between catalase inhibitors and modulators of nitric oxide metabolism on tumor cell apoptosis.
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Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors.
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Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo.
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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.
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T cells contribute to tumor progression by favoring pro-tumoral properties of intra-tumoral myeloid cells in a mouse model for spontaneous melanoma.
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Targeting arginine metabolism pathway to treat arginine-dependent cancers.
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Targeting macrophages in the tumour environment to enhance the efficacy of ?OX40 therapy.
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Targeting Tumor Microenvironment: Effects of Chinese Herbal Formulae on Macrophage-Mediated Lung Cancer in Mice.
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Tart Cherry Reduces Inflammation in Adipose Tissue of Zucker Fatty Rats and Cultured 3T3-L1 Adipocytes.
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Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models.
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Temporal profile of M1 and M2 responses in the hippocampus following early 24h of neurotrauma.
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Tetrahydroxystilbene glycoside antagonizes ?-amyloid-induced inflammatory injury in microglia cells by regulating PU.1 expression.
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The Applicability of a Human Immunohistochemical Panel to Mouse Models of Hepatocellular Neoplasia.
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THE EFFECT OF ARGINASE ON THE RETARDATION OF TUMOUR GROWTH.
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The effect of chemically modified alginates on macrophage phenotype and biomolecule transport.
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The effect of lymphoma and other neoplasms on hepatic and plasma enzymes of the host rat.
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The effects of arginase on neoplasm. I. The role of arginase in the immunosuppressive effects of extract from gastric cancer.
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The effects of WW2/WW3 domains of Smurf2 molecule on TGF-? signaling and arginase I gene expression.
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The Gut Microbiota, Kynurenine Pathway, and Immune System Interaction in the Development of Brain Cancer.
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The histological distribution of arginase activity in solid mouse tumor transplants and a comparison with ascites tumors and normal tissues.
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The immunoregulatory mechanisms of carcinoma for its survival and development.
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The immunosuppressive phenotype of tumor-infiltrating neutrophils is associated with obesity in kidney cancer patients.
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The inhibition of arginase by proline in cell-free extracts of mouse mammary tumour.
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The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer.
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The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines.
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The potential therapeutic effect of NG-hydroxy-nor-L-arginine in 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats.
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The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer.
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The Promise of Plant-Derived Substances as Inhibitors of Arginase.
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The protective role of ellagitannins flavonoids pretreatment against N-nitrosodiethylamine induced-hepatocellular carcinoma.
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The Redox State of the Glutathione/Glutathione Disulfide Couple Mediates Intracellular Arginase Activation in HCT-116 Colon Cancer Cells.
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The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
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The role of SHIP1 in macrophage programming and activation.
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The significance of arginase I administration on the survival of mice bearing NS-1 myeloma cells.
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The significance of arginase-1 expression in the diagnosis of liver cancer: A protocol for a systematic review.
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Thin-layer chromatography-bioautographic method for the detection of arginase inhibitors.
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TNF-?-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma.
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TNF-alpha contributes to endothelial dysfunction by upregulating arginase in ischemia/reperfusion injury.
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Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
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Toxoplasma ROP16I/III ameliorated inflammatory bowel diseases via inducing M2 phenotype of macrophages.
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Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers.
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Transforming growth factor-beta stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity.
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TREATMENT of cancer with arginase.
Neoplasms
Tumor-associated dendritic cells: molecular mechanisms to suppress antitumor immunity.
Neoplasms
Tumor-Associated Macrophages: Therapeutic Targets for Skin Cancer.
Neoplasms
Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development.
Neoplasms
Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I.
Neoplasms
Tumour effect on arginine/ornithine metabolic relationship in hypertrophic mouse kidney.
Neoplasms
Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
Neoplasms
uPAR induces expression of transforming growth factor ? and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.
Neoplasms
Urea cycle pathway targeted therapeutic action of naringin against ammonium chloride induced hyperammonemic rats.
Neoplasms
Uterine Carcinosarcoma with Alpha-Fetoprotein-Producing Hepatoid Component: A Case Report and Literature Review.
Neoplasms
VitA or VitD ameliorates bronchopulmonary dysplasia by regulating the balance between M1 and M2 macrophages.
Neoplasms
Vitamin D improves sunburns by increasing autophagy in M2 macrophages.
Neoplasms
Vitamin U has a protective effect on valproic acid-induced renal damage due to its anti-oxidant, anti-inflammatory, and anti-fibrotic properties.
Neoplasms
Well differentiated arginase-1 negative hepatocellular carcinoma.
Neoplasms
Wnt-3a alleviates neuroinflammation after ischemic stroke by modulating the responses of microglia/macrophages and astrocytes.
Neoplasms
[Adipose-derived stem cells promote the polarization from M1 macrophages to M2 macrophages].
Neoplasms
[Arginase a marker of cancerogenesis. II. Monitoring of patients after resection of colorectal liver metastases]
Neoplasms
[Arginase activity in blood serum of patients with acute and chronic pancreatitis]
Neoplasms
[Arginase as a marker of cancerogenesis. I. Monitoring patients after resection of colorectal cancer]
Neoplasms
[Arginase as a marker of cancerogenesis. III. Comparison of arginase activity with CEA and Ca 19-9 in liver metastases of colorectal cancer]
Neoplasms
[Blood arginase in cancer patients.]
Neoplasms
[Brain arginase isoenzyme activity during the growth of neurinomas]
Neoplasms
[Changes in arginase activity during neurinoma growth]
Neoplasms
[Comparative study of the activity of arginase isoenzymes in brain tumors of humans and experimental animals]
Neoplasms
[Correlation between autophagy and polarization of macrophages in atherosclerosis plaque in arteriosclerosis obliterans amputees].
Neoplasms
[Detection and analysis of phenotypes of tumor-associated macrophages in mouse model of spontaneous breast cancer].
Neoplasms
[Effect of acupoint thread-embedding on macrophage polarization of epididymis adipose tissue in obese mice].
Neoplasms
[Effect of decellularized adipose tissue combined with vacuum sealing drainage on wound inflammation in pigs].
Neoplasms
[Effect of polysaccharides from cancer urine and tissues on liver catalase and arginase.]
Neoplasms
[Effect of vitamin A in significant doses on incorporation of (14C) retinol, acceptor capacity of tRNA and activity of certain enzymes in tissues and plasma membranes of cells in the presence of Guerin's carcinoma]
Neoplasms
[Effects of butylphthalide on microglia activation in frontal lobe of rats after chronic sleep deprivation].
Neoplasms
[Effects of lithium carbonate nanosized particles on nitric oxide production and arginase activity in tumor and peritoneal macrophages in hepatocellular carcinoma 29].
Neoplasms
[Effects of metformin on the polarization and Notch 1 expression of RAW264.7 macrophages].
Neoplasms
[Enzymes in benign and malignant tumors of the liver; arginase and histidase.]
Neoplasms
[EXPLORATION OF ARGINASE ACTIVITY IN THE COURSE OF LIVER DISEASES, TUMORS AND INCLUSIVE.]
Neoplasms
[Immune function of myeloid-derived suppressor cells and its mechanism in obstructive sleep apnea syndrome].
Neoplasms
[Interferon regulatory factor 5 (IRF5) regulates the differentiation of bone marrow-derived macrophages in mice].
Neoplasms
[Progress in functions and mechanisms of immunosuppressive neutrophil subsets: An update].
Neoplasms
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Neoplasms
[Regulatory effect of bone marrow mesenchymal stem cells on polarization of macrophages].
Neoplasms
[Role of arginase-1 expression in distinguishing hepatocellular carcinoma from non-hepatocellular tumors].
Neoplasms
[Role of arginine and arginase in tumors]
Neoplasms
[Serum arginase activity in patients with liver cirrhosis and hepatocellular carcinoma]
Neoplasms
[Study of arginase activity of mixed saliva in cancer].
Neoplasms
[Therapeutic effect of enhancer of Zeste homolog 2 inhibitor GSK343 on periodontitis by regulating macrophage differentiation].
Neoplasms, Basal Cell
Significance of arginase and ornithine in malignant tumors of the human skin.
Neoplasms, Nerve Tissue
[Comparative study of the activity of arginase isoenzymes in brain tumors of humans and experimental animals]
Neoplasms, Squamous Cell
Significance of arginase and ornithine in malignant tumors of the human skin.
Nephritis
L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.
Neurilemmoma
[Brain arginase isoenzyme activity during the growth of neurinomas]
Neurilemmoma
[Changes in arginase activity during neurinoma growth]
Neurilemmoma
[Comparative study of the activity of arginase isoenzymes in brain tumors of humans and experimental animals]
Neuroblastoma
IL-10 and ARG-1 concentrations in bone marrow and peripheral blood of metastatic neuroblastoma patients do not associate with clinical outcome.
Neuroblastoma
Macrophage-Derived IL1? and TNF? Regulate Arginine Metabolism in Neuroblastoma.
Neuroblastoma
Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity.
Neuroblastoma
Neuroblastoma arginine addiction subverts the anticancer immune response.
Neurodegenerative Diseases
Arginase as a Potential Biomarker of Disease Progression: A Molecular Imaging Perspective.
Neuroinflammatory Diseases
Arginase 1+ microglia reduce A? plaque deposition during IL-1?-dependent neuroinflammation.
Neuroinflammatory Diseases
Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice.
Neuroinflammatory Diseases
Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation.
Neuroinflammatory Diseases
Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis.
Neuroinflammatory Diseases
Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.
Neuroinflammatory Diseases
Modifying effect of intravenous laser therapy on the protein expression of arginase and epidermal growth factor receptor in type 2 diabetic patients.
Neuroinflammatory Diseases
The importance of nitric oxide and arginase in the pathogenesis of acute neuroinflammation: are those contra players with the same direction?
Non-alcoholic Fatty Liver Disease
Arginase 1: a potential marker of a common pattern of liver steatosis in HCV and NAFLD children.
Non-alcoholic Fatty Liver Disease
Arginine/citrulline cycle changes in diet-induced rat model of non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Citrulline supplementation attenuates the development of non-alcoholic steatohepatitis in female mice through mechanisms involving intestinal arginase.
Non-alcoholic Fatty Liver Disease
Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation.
Obesity
ADMA elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbid obese humans.
Obesity
Aging Modulates the Influence of Arginase on Endothelial Dysfunction in Obesity.
Obesity
Arginase I and the very low-density lipoprotein receptor are associated with phenotypic biomarkers for obesity.
Obesity
Arginase inhibition ameliorates adipose tissue inflammation in mice with diet-induced obesity.
Obesity
Arginase inhibition ameliorates hepatic metabolic abnormalities in obese mice.
Obesity
Arginase inhibition restores endothelial function in diet-induced obesity.
Obesity
Critical role for arginase 2 in obesity-associated pancreatic cancer.
Obesity
Early obesity leads to increases in hepatic arginase I and related systemic changes in nitric oxide and L-arginine metabolism in mice.
Obesity
Effects of fetal exposure to high-fat diet or maternal hyperglycemia on L-arginine and nitric oxide metabolism in lung.
Obesity
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Obesity
Increased levels of circulating arginase I in overweight compared to normal weight adolescents.
Obesity
Mechanisms of obesity-induced metabolic and vascular dysfunctions.
Obesity
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Obesity
Possible contribution of hepatocyte secretion to the elevation of plasma exosomal arginase-1 in high-fat diet-fed mice.
Obesity
Role of Arginase 2 in Murine Retinopathy Associated with Western Diet-Induced Obesity.
Obesity
Role of Arginase 2 in Systemic Metabolic Activity and Adipose Tissue Fatty Acid Metabolism in Diet-Induced Obese Mice.
Obesity
Semen Cuscutae Administration Improves Hepatic Lipid Metabolism and Adiposity in High Fat Diet-Induced Obese Mice.
Obesity
Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism?
Obesity
The immunosuppressive phenotype of tumor-infiltrating neutrophils is associated with obesity in kidney cancer patients.
Obesity
The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis.
Obesity, Morbid
ADMA elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbid obese humans.
Obesity, Morbid
Microvascular Endothelial Dysfunction in Patients with Obesity.
Oligospermia
THE PECULIARITIES OF ARGINASE PATHWAY OF L-ARGININE IN SPERMATOZOA IN MEN WITH DIFFERENT FORMS OF PATHOSPERMIA.
Optic Nerve Injuries
Inflammation and blood-brain barrier breach remote from the primary injury following neurotrauma.
Optic Nerve Injuries
Integrin CD11b Deficiency Aggravates Retinal Microglial Activation and RGCs Degeneration After Acute Optic Nerve Injury.
Optic Nerve Injuries
Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2.
Optic Neuritis
Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis.
ornithine aminotransferase deficiency
Biomarkers identified in inborn errors for lysine, arginine, and ornithine.
ornithine carbamoyltransferase deficiency
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
ornithine carbamoyltransferase deficiency
Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl.
ornithine carbamoyltransferase deficiency
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
ornithine carbamoyltransferase deficiency
Genetic approach to prenatal diagnosis in urea cycle defects.
ornithine carbamoyltransferase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
ornithine carbamoyltransferase deficiency
Liver transplantation may prevent neurodevelopmental deterioration in high-risk patients with urea cycle disorders.
ornithine carbamoyltransferase deficiency
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
ornithine carbamoyltransferase deficiency
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
ornithine carbamoyltransferase deficiency
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
ornithine carbamoyltransferase deficiency
[The dibasic amino acid metabolic disorders]
Ornithine Carbamoyltransferase Deficiency Disease
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
Ornithine Carbamoyltransferase Deficiency Disease
Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl.
Ornithine Carbamoyltransferase Deficiency Disease
Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts.
Ornithine Carbamoyltransferase Deficiency Disease
Genetic approach to prenatal diagnosis in urea cycle defects.
Ornithine Carbamoyltransferase Deficiency Disease
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Ornithine Carbamoyltransferase Deficiency Disease
Liver transplantation may prevent neurodevelopmental deterioration in high-risk patients with urea cycle disorders.
Ornithine Carbamoyltransferase Deficiency Disease
Long-term outcome of urea cycle disorders: Report from a nationwide study in Japan.
Ornithine Carbamoyltransferase Deficiency Disease
Physical, cognitive, and social status of patients with urea cycle disorders in Japan.
Ornithine Carbamoyltransferase Deficiency Disease
Role of liver transplantation in urea cycle disorders: Report from a nationwide study in Japan.
Ornithine Carbamoyltransferase Deficiency Disease
[The dibasic amino acid metabolic disorders]
Osteoarthritis
Arginase levels are increased in patients with rheumatoid arthritis.
Osteoarthritis
Critical role for arginase II in osteoarthritis pathogenesis.
Osteomyelitis
Endodontic Infection-induced Inflammation Resembling Osteomyelitis of the Jaws in Toll-like Receptor 2/Interleukin 10 Double-knockout Mice.
Osteosarcoma
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
Osteosarcoma
Hypoxia-induced proliferation of HeLa cells depends on epidermal growth factor receptor-mediated arginase II induction.
Osteosarcoma
Hypoxic Proliferation of Osteosarcoma Cells Depends on Arginase II.
Ovarian Neoplasms
Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent.
Ovarian Neoplasms
Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA.
Ovarian Neoplasms
Influence of CA125, platelet count and neutrophil to lymphocyte ratio on the immune system of ovarian cancer patients.
Ovarian Neoplasms
Murine ovarian cancer vascular leukocytes require arginase-1 activity for T cell suppression.
Overweight
Increased levels of circulating arginase I in overweight compared to normal weight adolescents.
Pancreatic Neoplasms
Arginase II expressed in cancer-associated fibroblasts indicates tissue hypoxia and predicts poor outcome in patients with pancreatic cancer.
Pancreatic Neoplasms
Circulating myeloid-derived suppressor cells in patients with pancreatic cancer.
Pancreatic Neoplasms
Critical role for arginase 2 in obesity-associated pancreatic cancer.
Pancreatic Neoplasms
Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity.
Pancreatic Neoplasms
Expression of Markers of Hepatocellular Differentiation in Pancreatic Acinar Cell Neoplasms: ?A Potential Diagnostic Pitfall.
Pancreatic Neoplasms
Growth inhibitory effect of L-canavanine against MIA PaCa-2 pancreatic cancer cells is not due to conversion to its toxic metabolite canaline.
Pancreatic Neoplasms
Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.
Pancreatic Neoplasms
uPAR induces expression of transforming growth factor ? and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.
Pancreatic Neoplasms
[Arginase activity in blood serum of patients with acute and chronic pancreatitis]
Pancreatic Neoplasms
[Usefulness of preoperative assay of arginase in pancreatic cancer patients]
Pancreatitis
Inhibition of arginase activity ameliorates L-arginine-induced acute pancreatitis in rats.
Pancreatitis
[Changes of serum arginase in patients with acute cholecystitis and pancreatitis]
Pancreatitis
[Rat liver arginase activity in acute experimental pancreatitis]
Pancreatitis, Chronic
[Arginase activity in blood serum of patients with acute and chronic pancreatitis]
pantoate-beta-alanine ligase (amp-forming) deficiency
Ammonia Control in Children Ages 2 Months through 5 Years with Urea Cycle Disorders: Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate.
pantoate-beta-alanine ligase (amp-forming) deficiency
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
pantoate-beta-alanine ligase (amp-forming) deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
Papilloma
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas.
Papilloma
Induction of arginase in rabbit epithelium by the Shope rabbit papilloma virus.
Papilloma
On the arginase of the Shope papillomas.
Papilloma
Studies of the mechanism of action of the Shope rabbit papilloma virus. I. Concerning the nature of the induction of arginase in the infected cells.
Papilloma
Unsuccessful trial of gene replacement in arginase deficiency.
Papilloma
[Purification and properties of L-arginase of papillomas induced with the rabbit papilloma virus]
Paraparesis, Spastic
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
Paraplegia
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Paraplegia
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
Paraplegia
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Parasitemia
Rat models to investigate host macrophage defense against Trypanosoma cruzi.
Parasitemia
S. mansoni-T. cruzi co-infection modulates arginase-1/iNOS expression, liver and heart disease in mice.
Parasitic Diseases
Arginase Activity in Eisenia andrei Coelomocytes: Function in the Earthworm Innate Response.
Parasitic Diseases
Arginase in parasitic infections: macrophage activation, immunosuppression, and intracellular signals.
Parasitic Diseases
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections.
Parasitic Diseases
Resistin-Like Molecule Alpha Regulates IL-13-Induced Chemokine Production but not Allergen-Induced Airway Responses.
Parasitic Diseases
Thin-layer chromatography-bioautographic method for the detection of arginase inhibitors.
Pemphigus
Arginase 1+ IL-10+ polymorphonuclear myeloid-derived suppressor cells are elevated in patients with active pemphigus and correlate with an increased Th2/Th1 response.
Pemphigus
Co-expression of inducible nitric oxide synthase and arginases in different human monocyte subsets. Apoptosis regulated by endogenous NO.
Periodontal Diseases
Salivary arginase in patients with adult periodontitis.
Periodontitis
Arginine-Nitric Oxide-Polyamine Metabolism in Periodontal Disease.
Periodontitis
Salivary arginase in patients with adult periodontitis.
Peripheral Nervous System Diseases
Arginase deficiency with new phenotype and a novel mutation: contemporary summary.
Peritonitis
Corrigendum to "Cytochrome P450 1A1 enhances Arginase-1 expression, which reduces LPS-induced mouse peritonitis by targeting JAK1/STAT6" [Cell. Immunol. 349 (2020) 104047].
Peritonitis
Cytochrome P450 1A1 enhances Arginase-1 expression, which reduces LPS-induced mouse peritonitis by targeting JAK1/STAT6.
Peritonitis
Decrease in lung nitric oxide production after peritonitis in mice with sickle cell disease.
Peritonitis
Decreased exhaled nitric oxide as a marker of postinsult immune paralysis.
Persistent Infection
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
Persistent Infection
Crystallization and preliminary crystallographic studies of Helicobacter pylori arginase.
Persistent Infection
Nitric oxide production is downregulated during respiratory syncytial virus persistence by constitutive expression of arginase 1.
Persistent Infection
Suppression of T-cell functions by human granulocyte arginase.
phenylalanine 4-monooxygenase deficiency
Biopterins in arginase, dihydropteridine reductase and phenylalanine hydroxylase deficiency.
Phenylketonurias
Arginase deficiency and phenylketonuria.
Phenylketonurias
Biopterins in arginase, dihydropteridine reductase and phenylalanine hydroxylase deficiency.
Phenylketonurias
Vascular Arginase Is a Relevant Target to Improve Cerebrovascular Endothelial Dysfunction in Rheumatoid Arthritis: Evidence from the Model of Adjuvant-Induced Arthritis.
Pleural Effusion
A potential role for nitric oxide pathway in tuberculous pleural effusion.
Pneumococcal Infections
Arginase 1 activity worsens lung-protective immunity against Streptococcus pneumoniae infection.
Pneumonia
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Pneumonia
A potential role for nitric oxide pathway in tuberculous pleural effusion.
Pneumonia
Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice.
Pneumonia
Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
Pneumonia
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Pneumonia
Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.
Pneumonia
Arginase inhibition prevents inflammation and remodeling in a Guinea pig model of chronic obstructive pulmonary disease.
Pneumonia
Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences.
Pneumonia
Cell- and isoform-specific increases in arginase expression in acute silica-induced pulmonary inflammation.
Pneumonia
Effect of arginase inhibition on pulmonary L-arginine metabolism in murine pseudomonas pneumonia.
Pneumonia
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis.
Pneumonia
Human eosinophil granulocytes do not express the enzyme arginase.
Pneumonia
In utero environmental tobacco smoke exposure alters gene expression in lungs of adult BALB/c mice.
Pneumonia
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Pneumonia
MS4A4A Regulates Arginase 1 Induction during Macrophage Polarization and Lung Inflammation in Mice.
Pneumonia
Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.
Pneumonia
Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4.
Pneumonia
Role of arginase 1 from myeloid cells in th2-dominated lung inflammation.
Pneumonia
The Inhibition of Caspase-1- Does Not Revert Particulate Matter (PM)-Induced Lung Immunesuppression in Mice.
Pneumonia
Vagal-?7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection.
Pneumoperitoneum
Effect of Pneumoperitoneum on Oxidative Stress and Inflammation via the Arginase Pathway in Rats.
Pneumoperitoneum
Erratum to: The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats.
Pneumoperitoneum
The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats.
Pre-Eclampsia
Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia.
Pre-Eclampsia
Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis.
Pre-Eclampsia
Different profiles of circulating arginase 2 in subtypes of preeclampsia pregnant women.
Pre-Eclampsia
Effects of arginase genetic polymorphisms on nitric oxide formation in healthy pregnancy and in preeclampsia.
Pre-Eclampsia
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Pre-Eclampsia
Influence of the AT(2) receptor on the L-arginine-nitric oxide pathway and effects of (-)-epicatechin on HUVECs from women with preeclampsia.
Pre-Eclampsia
Inhibition of pregnancy-associated granulocytic myeloid-derived suppressor cell expansion and arginase-1 production in preeclampsia.
Pre-Eclampsia
L-arginine depletion in preeclampsia orients nitric oxide synthase toward oxidant species.
Pre-Eclampsia
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in pre-eclamptic women.
Pre-Eclampsia
Red blood cells from patients with pre-eclampsia induce endothelial dysfunction.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in etiology.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pegylated arginase I: a potential therapeutic approach in T-ALL.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Vincristine could partly suppress stromal support to T-ALL blasts during pegylated arginase I treatment.
Priapism
Intravascular hemolysis and the pathophysiology of sickle cell disease.
Prolidase Deficiency
Increased manganese content and reduced arginase activity in erythrocytes of a patient with prolidase deficiency (iminodipeptiduria).
Prostatic Diseases
Evaluation of serum arginase activity in benign prostatic hypertrophy and prostatic cancer.
Prostatic Diseases
Possible implications of arginase and diamine oxidase in prostatic carcinoma.
Prostatic Hyperplasia
Arginase activity in prostatic tissue of patients with benign prostatic hyperplasia and prostatic carcinoma.
Prostatic Hyperplasia
Evaluation of serum arginase activity in benign prostatic hypertrophy and prostatic cancer.
Prostatic Hyperplasia
Possible implications of arginase and diamine oxidase in prostatic carcinoma.
Prostatic Neoplasms
Altered Cd8+ T lymphocyte Response Triggered by Arginase 1: Implication for Fatigue Intensification during Localized Radiation Therapy in Prostate Cancer Patients.
Prostatic Neoplasms
Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
Prostatic Neoplasms
Apoptosis-inducing high (.)NO concentrations are not sustained either in nascent or in developed cancers.
Prostatic Neoplasms
Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression.
Prostatic Neoplasms
Arginase II expressed in cancer-associated fibroblasts indicates tissue hypoxia and predicts poor outcome in patients with pancreatic cancer.
Prostatic Neoplasms
Arginase purified from endophytic Pseudomonas aeruginosa IH2: Induce apoptosis through both cell cycle arrest and MMP loss in human leukemic HL-60 cells.
Prostatic Neoplasms
Deprivation of arginine by recombinant human arginase in prostate cancer cells.
Prostatic Neoplasms
Diagnostic performance of serum arginase activity in prostatic cancer.
Prostatic Neoplasms
Disruption of arginase II alters prostate tumor formation in TRAMP mice.
Prostatic Neoplasms
Evaluation of serum arginase activity in benign prostatic hypertrophy and prostatic cancer.
Prostatic Neoplasms
Expression of arginase II in prostate cancer.
Prostatic Neoplasms
Expression of immunomodulating genes in prostate cancer and benign prostatic tissue.
Prostatic Neoplasms
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer.
Prostatic Neoplasms
Some new approaches to potential test systems for drugs against prostatic cancer.
Prostatic Neoplasms
Tumor-associated dendritic cells: molecular mechanisms to suppress antitumor immunity.
Protein-Energy Malnutrition
Biochemical changes in saliva of malnourished children.
Protein-Energy Malnutrition
Protein energy malnutrition increases arginase activity in monocytes and macrophages.
Proteinuria
Effects of Arginase Inhibition in Hypertensive Hyperthyroid Rats.
Protozoan Infections
Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Pseudomonas Infections
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Psoriasis
Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation.
Psoriasis
Arginase activity and polyamine biosynthesis in psoriasis.
Psoriasis
Arginase-1 overexpression induces cationic amino acid transporter-1 in psoriasis.
Psoriasis
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Psoriasis
Possible significance of elevated arginase activity in psoriasis scales.
Pulmonary Arterial Hypertension
Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Pulmonary Arterial Hypertension
Arginase inhibition protects against hypoxia?induced pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension in Rats Due to Age-related Arginase Activation in Intermittent Hypoxia.
Pulmonary Disease, Chronic Obstructive
Arginase and pulmonary diseases.
Pulmonary Disease, Chronic Obstructive
Arginase inhibition prevents inflammation and remodeling in a Guinea pig model of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Arginine Therapy for Lung Diseases.
Pulmonary Disease, Chronic Obstructive
Asymmetric Dimethylarginine in Chronic Obstructive Pulmonary Disease (ADMA in COPD).
Pulmonary Disease, Chronic Obstructive
Elevated levels of arginase activity are related to inflammation in patients with COPD exacerbation.
Pulmonary Disease, Chronic Obstructive
Expansion of myeloid-derived suppressor cells in chronic obstructive pulmonary disease and lung cancer: potential link between inflammation and cancer.
Pulmonary Disease, Chronic Obstructive
Increased platelet and erythrocyte arginase activity in chronic obstructive pulmonary disease associated with tobacco or wood smoke exposure.
Pulmonary Disease, Chronic Obstructive
Metabolomic profiling of doxycycline treatment in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Positive correlation of airway resistance and serum asymmetric dimethylarginine level in COPD patients with systemic markers of low-grade inflammation.
Pulmonary Disease, Chronic Obstructive
Role of nitric oxide synthase/arginase balance in bronchial reactivity in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Targeting arginase and nitric oxide metabolism in chronic airway diseases and their co-morbidities.
Pulmonary Embolism
Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism.
Pulmonary Embolism
Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.
Pulmonary Embolism
Up-regulation of arginase II contributes to pulmonary vascular endothelial cell dysfunction during experimental pulmonary embolism.
Pulmonary Fibrosis
Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice.
Pulmonary Fibrosis
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
Pulmonary Fibrosis
Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway.
Quadriplegia
A successful trial of enzyme replacement therapy in a case of argininemia.
Quadriplegia
Prenatal diagnosis for arginase deficiency: a case study.
Quadriplegia
Three novel mutations in the liver-type arginase gene in three unrelated Japanese patients with argininemia.
Reflex, Abnormal
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development.
Renal Insufficiency
Arginase inhibition slows the progression of renal failure in rats with renal ablation.
Renal Insufficiency, Chronic
Impaired L-arginine uptake but not arginase contributes to endothelial dysfunction in rats with chronic kidney disease.
Renal Insufficiency, Chronic
Intravascular hemolysis and the pathophysiology of sickle cell disease.
Reperfusion Injury
Arginase 2 is a mediator of ischemia-reperfusion injury in the kidney through regulation of nitrosative stress.
Reperfusion Injury
Arginase as a target for treatment of myocardial ischemia-reperfusion injury.
Reperfusion Injury
Arginase-2 mediates renal ischemia-reperfusion injury.
Reperfusion Injury
Arginase-2 protects myocardial ischemia-reperfusion injury via NF-?B/TNF-? pathway.
Reperfusion Injury
Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
Reperfusion Injury
Direct relationship between levels of TNF-alpha expression and endothelial dysfunction in reperfusion injury.
Reperfusion Injury
Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury.
Reperfusion Injury
Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus.
Reperfusion Injury
Effects of N-acetylcysteine on arginase, ornithine and nitric oxide in renal ischemia-reperfusion injury.
Reperfusion Injury
In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury.
Reperfusion Injury
Mechanisms of vasculopathy in sickle cell disease and thalassemia.
Reperfusion Injury
Renal tubular arginase-2 participates in the formation of the corticomedullary urea gradient and attenuates kidney damage in ischemia-reperfusion injury in mice.
Reperfusion Injury
The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Respiratory Hypersensitivity
Pharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In Vivo.
Respiratory Hypersensitivity
The therapeutic potential of drugs targeting the arginase pathway in asthma.
Respiratory Insufficiency
[Carbamoyl ornithine transferase, arginase and cobalt-activated acylase in patients during asthma attacks or patients with respiratory failure]
Retinal Degeneration
Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis.
Retinopathy of Prematurity
Arginase 2 deletion reduces neuro-glial injury and improves retinal function in a model of retinopathy of prematurity.
Rhinitis, Allergic
Increased expression of arginase I and II in allergic nasal mucosa.
Rhinitis, Allergic
Recent Patents in Allergy/Immunology: Use of arginase inhibitors in the treatment of asthma and allergic rhinitis.
Rhinitis, Allergic
Serum nitrite/nitrate and arginase levels in patients with allergic rhinitis.
Rhinitis, Allergic
The effect of montelukast sodium on serum arginase levels in patients with seasonal allergic rhinitis.
Rhinitis, Allergic, Seasonal
The effect of montelukast sodium on serum arginase levels in patients with seasonal allergic rhinitis.
Root Resorption
Cellular and Molecular Pathways Leading to External Root Resorption.
Salmonella Infections
Arginase modulates Salmonella induced nitric oxide production in RAW264.7 macrophages and is required for Salmonella pathogenesis in mice model of infection.
Salmonella Infections
Pathological physiology of salmonellosis. V. Serum arginase and glutamic-oxaloacetic transaminase in children with typhoid fever.
Sarcoidosis
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis.
Sarcoma
Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.
Sarcoma
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
Sarcoma
Mapping the immunosuppressive environment in uterine tumors: implications for immunotherapy.
Sarcoma
Microenvironmental arginine depletion by macrophages in vivo.
Sarcoma 180
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
Schistosomiasis
Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis.
Schistosomiasis
Assessment of serum arginase activity in intestinal and hepatic schistosomiasis.
Schistosomiasis
Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.
Schistosomiasis
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.
Schistosomiasis
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model.
Schistosomiasis
Incomplete deletion of IL-4R? by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis.
Schistosomiasis
Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis.
Schistosomiasis
Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages.
Schistosomiasis
Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity.
Schistosomiasis mansoni
Arginase activity in peripheral blood of patients with intestinal schistosomiasis, Wonji, Central Ethiopia.
Scrapie
Alterations of arginase activity in scrapie-infected mice and in amyotrophic lateral sclerosis.
Seizures
A successful trial of enzyme replacement therapy in a case of argininemia.
Seizures
Arginase deficiency presenting with convulsions.
Seizures
Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency.
Seizures
Effects of febrile and afebrile seizures on oxidant state in children.
Seizures
Functional significance of the activities of glutaminase and ornithine-?-aminotransferase in rat brain.
Seizures
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Seizures
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Seizures
Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.
Seizures
Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse.
Seizures
Manganese and epilepsy: brain glutamine synthetase and liver arginase activities in genetically epilepsy prone and chronically seizured rats.
Seizures
Prenatal diagnosis for arginase deficiency: a case study.
Seizures
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Seizures
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Seizures
Spermidine influence on the nitric oxide synthase and arginase activity relationship during experimentally induced seizures.
Sepsis
Arginine and immunity.
Sepsis
Differential expression of arginase and iNOS in the lung in sepsis.
Sepsis
Hepatic glutamine metabolism in the septic rat.
Sepsis
Immunotherapy-on-Chip Against an Experimental Sepsis Model.
Sepsis
Increased plasma arginase activity in human sepsis: association with increased circulating neutrophils.
Sepsis
Inhibition of Host Arginase Activity Against Staphylococcal Bloodstream Infection by Different Metabolites.
Sepsis
Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients.
Sepsis
Pseudomonas aeruginosa is associated with increased lung cytokines and asymmetric dimethylarginine compared with methicillin-resistant Staphylococcus aureus.
Sepsis
Regulation of T cell receptor CD3zeta chain expression by L-arginine.
Silicosis
Cell- and isoform-specific increases in arginase expression in acute silica-induced pulmonary inflammation.
Skin Abnormalities
[Clinical and biochemical alterations in rats treated with high doses of vitamin A]
Sleep Apnea, Obstructive
Arginase activity and nitric oxide levels in patients with obstructive sleep apnea syndrome.
Small Cell Lung Carcinoma
Arginase Pathway Markers of Immune-Microenvironment in Thymic Epithelial Tumors and Small Cell Lung Cancer.
Small Cell Lung Carcinoma
Contactin 1 modulates pegylated arginase resistance in small cell lung cancer through induction of epithelial-mesenchymal transition.
Small Cell Lung Carcinoma
Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer.
Spinal Cord Diseases
Arginase-1 expressing microglia in close proximity to motor neurons were increased early in disease progression in canine degenerative myelopathy, a model of amyotrophic lateral sclerosis.
Spinal Cord Injuries
Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration.
Spinal Cord Injuries
Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury.
Spinal Cord Injuries
Regulation of nitric oxide generation by up-regulated arginase I in rat spinal cord injury.
Spinal Cord Vascular Diseases
Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state.
Squamous Cell Carcinoma of Head and Neck
Arginase and C-reactive protein as potential serum-based biomarker of head and neck squamous cell carcinoma patients of north east India.
Squamous Cell Carcinoma of Head and Neck
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Squamous Cell Carcinoma of Head and Neck
Modulation of L-Arginine-Arginase Metabolic Pathway Enzymes: Immunocytochemistry and mRNA Expression in Peripheral Blood and Tissue Levels in Head and Neck Squamous Cell Carcinomas in North East India.
Squamous Cell Carcinoma of Head and Neck
The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
ST Elevation Myocardial Infarction
Arginase 1 is upregulated at admission in patients with ST-elevation myocardial infarction.
ST Elevation Myocardial Infarction
The shifted balance of arginine metabolites in acute myocardial infarction patients and its clinical relevance.
Staphylococcal Infections
Inhibition of Host Arginase Activity Against Staphylococcal Bloodstream Infection by Different Metabolites.
Starvation
An arginase-based system for selection of transfected CHO cells without the use of toxic chemicals.
Starvation
Arginase activity is a useful marker of nitrogen limitation during alcoholic fermentations.
Starvation
Axenic Leishmania amazonensis promastigotes sense both the external and internal arginine pool distinctly regulating the two transporter-coding genes.
Starvation
Capillary electrophoresis reveals polyamine metabolism modulation in Leishmania (Leishmania) amazonensis wild type and arginase knockout mutants under arginine starvation.
Starvation
Catabolic synergism: a cooperation between the availability of substrate and the need for nitrogen in the regulation of arginine catabolism in Saccharomyces cerevisiae.
Starvation
Distribution of amino acids and amino-acid enzymes in whole kidney and renal cortex. Effect of 24-h starvation.
Starvation
Effects of cortisol or starvation on the activities of four enzymes in small intestine and liver of the rat during development.
Starvation
induction and derepression of arginase and ornithine transaminase in different strains of Saccharomyces cerevisiae.
Starvation
Intramitochondrial localization of arginase appearing in chicken liver upon starvation.
Starvation
Isolation and screening of extracellular anticancer enzymes from halophilic and halotolerant bacteria from different saline environments in Iran.
Starvation
Molecular charcteristics of chicken kidney arginase.
Starvation
Oxidative stress and some biochemical parameters during starvation and refeeding in Astacus leptodactylus (Esch., 1823).
Starvation
Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.
Starvation
The effect of adrenalectomy and starvation on arginase and ornithine-transcarbamylase activities in the liver of rats during development.
Starvation
Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.
Status Epilepticus
Recurrent hepatic failure and status epilepticus: an uncommon presentation of hyperargininemia.
Stomach Neoplasms
Circulating and tumor-infiltrating arginase 1-expressing cells in gastric adenocarcinoma patients were mainly immature and monocytic Myeloid-derived suppressor cells.
Stomach Neoplasms
Content of glucocorticoid receptor and arginase in gastric cancer and normal gastric mucosal tissues.
Stomach Neoplasms
Effect of arginase on splenic killer cell activity in patients with gastric cancer.
Stomach Neoplasms
Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer.
Stomach Neoplasms
Immunohistochemical study of arginase in cancer of the stomach.
Stomach Neoplasms
Regulation of arginase production by glucocorticoid in three human gastric cancer cell lines.
Stomach Neoplasms
Serum arginase level in patients with gastric cancer.
Stomach Neoplasms
The effects of arginase on neoplasm. I. The role of arginase in the immunosuppressive effects of extract from gastric cancer.
Stomach Ulcer
Immunohistochemical study of arginase in cancer of the stomach.
Strabismus
Anesthetic management of a pediatric patient with arginase-1 deficiency undergoing strabismus operation: a case report.
Stroke
Alteration of microRNA 340-5p and Arginase-1 Expression in Peripheral Blood Cells during Acute Ischemic Stroke.
Stroke
Arginase I release from activated neutrophils induces peripheral immunosuppression in a murine model of stroke.
Stroke
CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice.
Stroke
Effect of stroke on arginase expression and localization in the rat brain.
Stroke
Effectiveness of arginase inhibitors against experimentally induced stroke.
Stroke
Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
Stroke
Pair housing reverses post-stroke depressive behavior in mice.
Stroke
[New insights into arginase. Part II. Role in physiology and pathology]
Subarachnoid Hemorrhage
Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit.
Tauopathies
Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.
Teratoma
Embryonic Stem Cells Promoting Macrophage Survival and Function are Crucial for Teratoma Development.
Thrombosis
Arginase activity is increased by thrombin: a mechanism for endothelial dysfunction in arterial thrombosis.
Thrombosis
Arginase blockade lessens endothelial dysfunction after thrombosis.
Thrombosis
Down-regulation of metabolic proteins in hepatocellular carcinoma with portal vein thrombosis.
Thrombosis
L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.
Thrombosis
Mature coconut water exhibits antidiabetic and antithrombotic potential via L-arginine-nitric oxide pathway in alloxan induced diabetic rats.
Thrombosis
Thrombin induces endothelial arginase through AP-1 activation.
Tics
Melanoma-initiating cells exploit M2 macrophage TGF? and arginase pathway for survival and proliferation.
Toxemia
[The effect of antiprotein plasma on humoral resistance in children with severe burns]
Toxoplasmosis
Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection.
Tremor
Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.
Triple Negative Breast Neoplasms
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
Triple Negative Breast Neoplasms
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells.
Trypanosomiasis, African
Serum arginase, a biomarker of treatment efficacy in human African trypanosomiasis.
Tuberculosis
A potential role for nitric oxide pathway in tuberculous pleural effusion.
Tuberculosis
Adaptation of M. tuberculosis to impaired host immunity in HIV-infected patients.
Tuberculosis
Arginase-1 expression in granulomas of tuberculosis patients.
Tuberculosis
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis.
Tuberculosis
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas.
Tuberculosis
Small-molecule arginase inhibitors.
Tuberculosis
Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis.
Tumor Virus Infections
Change in the structure of Shope papilloma virus-induced arginase associated with mutation of the virus.
Tumor Virus Infections
Induction of arginase activity with the Shope papilloma virus in tissue culture cells from an argininemic patient.
Tumor Virus Infections
Studies on the arginase activity of Shope papilloma: possible presence of isozymes.
Tumor Virus Infections
USE OF THE SHOPE PAPILLOMA VIRUS-INDUCED ARGINASE AS A BIOCHEMICAL MARKER IN VITRO.
Typhoid Fever
Pathological physiology of salmonellosis. V. Serum arginase and glutamic-oxaloacetic transaminase in children with typhoid fever.
Urea Cycle Disorders, Inborn
A Case of Hyperargininaemia Presenting at Unusually Low Age.
Urea Cycle Disorders, Inborn
A patient with arginase deficiency and episodic hyperammonemia successfully treated with menses cessation.
Urea Cycle Disorders, Inborn
AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse.
Urea Cycle Disorders, Inborn
Anesthetic management of a patient with arginase deficiency undergoing liver transplantation.
Urea Cycle Disorders, Inborn
Anesthetic management of a pediatric patient with arginase-1 deficiency undergoing strabismus operation: a case report.
Urea Cycle Disorders, Inborn
Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme.
Urea Cycle Disorders, Inborn
Arginase Deficiency Presenting as Acute Encephalopathy.
Urea Cycle Disorders, Inborn
Arginase deficiency.
Urea Cycle Disorders, Inborn
Arginase I mRNA therapy - a novel approach to rescue arginase 1 enzyme deficiency.
Urea Cycle Disorders, Inborn
Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines.
Urea Cycle Disorders, Inborn
Arginase-1 deficiency in neural cells does not contribute to neurodevelopment or functional outcomes after sciatic nerve injury.
Urea Cycle Disorders, Inborn
Argininemia: a treatable genetic cause of progressive spastic diplegia simulating cerebral palsy: case reports and literature review.
Urea Cycle Disorders, Inborn
Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl.
Urea Cycle Disorders, Inborn
Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency.
Urea Cycle Disorders, Inborn
Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency.
Urea Cycle Disorders, Inborn
Creatine metabolism in patients with urea cycle disorders.
Urea Cycle Disorders, Inborn
Guanidino compound levels in blood, cerebrospinal fluid, and post-mortem brain material of patients with argininemia.
Urea Cycle Disorders, Inborn
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Urea Cycle Disorders, Inborn
Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy.
Urea Cycle Disorders, Inborn
Mutations and common variants in the human arginase 1 (ARG1) gene: Impact on patients, diagnostics, and protein structure considerations.
Urea Cycle Disorders, Inborn
Neurological Deterioration in Three Siblings: Exploring the Spectrum of Argininemia.
Urea Cycle Disorders, Inborn
Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.
Uremia
Arginase activity of human erythrocyte ghosts in uremia.
Uremia
Liver arginase activity as related to blood urea in acute uremia of new-born rats.
Uremia
[Effect of flavonoids on aspects of nitrogen metabolism in experimental uremia]
Uremia
[Hepatic and renal arginase in uremia; experimental study in uremia produced by ligation of the ureters in guinea pig.]
Ureteral Obstruction
Selective inhibition of arginase-2 in endothelial cells but not proximal tubules reduces renal fibrosis.
Urinary Bladder Neoplasms
Pegylated Recombinant Human Arginase 1 Induces Autophagy and Apoptosis via the ROS-Activated AKT/mTOR Pathway in Bladder Cancer Cells.
Urinary Bladder, Neurogenic
Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury.
Uterine Cervical Neoplasms
Immunosuppression in cervical cancer with special reference to arginase activity.
Uterine Cervical Neoplasms
Recombinant Bacillus caldovelox Arginase Mutant (BCA-M) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Human Cervical Cancer Cells.
Uveitis
Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.
Uveitis
Coinduction of nitric oxide synthase and arginine metabolic enzymes in endotoxin-induced uveitis rats.
Uveitis
Propolis modulates NOS2/arginase-1 pathway in tropomyosin-induced experimental autoimmune uveitis.
Uveitis, Anterior
Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.
Varicocele
Major protein alterations in spermatozoa from infertile men with unilateral varicocele.
Varicose Ulcer
Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous leg ulcers.
Vascular Diseases
A Novel Arginase Inhibitor Derived from Scutellavia indica Restored Endothelial Function in ApoE-Null Mice Fed a High-Cholesterol Diet.
Vascular Diseases
Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia.
Vascular Diseases
Arginase Inhibitor 2,3,5,4'-Tetrahydroxystilbene-2-O-?-D-Glucoside Activates Endothelial Nitric Oxide Synthase and Improves Vascular Function.
Vascular Diseases
Arginase: a critical regulator of nitric oxide synthesis and vascular function.
Vascular Diseases
Endothelial arginase II and atherosclerosis.
Vascular Diseases
Endothelial arginase II responds to pharmacological inhibition by elevation in protein level.
Vascular Diseases
HYPOXIC UPREGULATION OF ARGINASE II IN HUMAN LUNG ENDOTHELIAL CELLS.
Vascular Diseases
Insights on the participation of Glu256 and Asp204 in the oligomeric structure and cooperative effects of human arginase type I.
Vascular Diseases
Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling.
Vascular Diseases
Korean red ginseng water extract restores impaired endothelial function by inhibiting arginase activity in aged mice.
Vascular Diseases
Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells.
Vascular Diseases
Role of arginase in vessel wall remodeling.
Vascular Diseases
Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology.
Vascular Diseases
The Redox State of the Glutathione/Glutathione Disulfide Couple Mediates Intracellular Arginase Activation in HCT-116 Colon Cancer Cells.
Vascular Diseases
Time course of vascular arginase expression and activity in spontaneously hypertensive rats.
Vascular Diseases
Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice.
Vascular Diseases
Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase.
Vascular System Injuries
Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium.
Vasospasm, Intracranial
Melatonin Ameliorates Cerebral Vasospasm After Experimental Subarachnoidal Haemorrhage Correcting Imbalance of Nitric Oxide Levels in Rats.
Venous Insufficiency
Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous leg ulcers.
Virus Diseases
Contribution of macrophage arginase in the intrinsic restriction of herpes simplex virus replication in permissive macrophage cultures induced by gamma-interferon containing products of activated spleen cells.
Virus Diseases
Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis.
Virus Diseases
Nitric oxide production is downregulated during respiratory syncytial virus persistence by constitutive expression of arginase 1.
Virus Diseases
Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis.
Virus Diseases
[SPECIES COMPOSITION OF INFECTIOUS FACTORS THAT CAUSE THE REACTIVE ARTHRITIS DEVELOPMENT AND THEIR EFFECT ON ARGINASE-NO-SYNTHASE REGULATORY SYSTEM OF PERIPHERAL BLOOD LYMPHOCYTES].
Vitamin A Deficiency
Influence of vitamin A on formation and excretion of end products of nitrogen catabolism in chicks.
Vitamin B 12 Deficiency
Involvement of Spermidine in the Reduced Lifespan of Caenorhabditis elegans During Vitamin B12 Deficiency.
Whooping Cough
Erythroid Suppressor Cells Compromise Neonatal Immune Response against Bordetella pertussis.
xaa-pro dipeptidase deficiency
Increased manganese content and reduced arginase activity in erythrocytes of a patient with prolidase deficiency (iminodipeptiduria).
Xanthomatosis, Cerebrotendinous
[A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta]
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3.5.3.1 arginase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
