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Information on EC 3.5.2.2 - dihydropyrimidinase and Organism(s) Arabidopsis thaliana

for references in articles please use BRENDA:EC3.5.2.2
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EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.2 dihydropyrimidinase
IUBMB Comments
Also acts on dihydrothymine and hydantoin.
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This record set is specific for:
Arabidopsis thaliana
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
dhp, dihydropyrimidine dehydrogenase, dihydropyrimidinase, hydantoinase, d-hydantoinase, dhp-1, dhpase, dihydropyrimidine amidohydrolase, dhp-2, padhpase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D-hydantoinase
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Dihydropyrimidinase
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hydantoin peptidase
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hydantoinase
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hydropyrimidine hydrase
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pyrimidine hydrase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
carboxylic acid amide hydrolysis
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SYSTEMATIC NAME
IUBMB Comments
5,6-dihydropyrimidine amidohydrolase
Also acts on dihydrothymine and hydantoin.
CAS REGISTRY NUMBER
COMMENTARY hide
9030-74-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5,6-dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
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?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DPYS_ARATH
531
0
57991
Swiss-Prot
Secretory Pathway (Reliability: 2)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rawls, J.M.
Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism
Genetics
172
1665-1674
2006
Caenorhabditis elegans (Q18677), Caenorhabditis elegans (Q21773), Drosophila melanogaster (Q2XST3), Drosophila melanogaster (Q8IPQ2), Drosophila melanogaster, Dictyostelium discoideum (Q55DL0), Mus musculus (Q9EQF5), Arabidopsis thaliana (Q9FMP3), Pseudomonas aeruginosa (Q9I676), Lachancea kluyveri (Q9P903), Drosophila melanogaster EP(3)3238 (Q2XST3), Drosophila melanogaster EP(3)3238 (Q8IPQ2)
Manually annotated by BRENDA team
Zrenner, R.; Riegler, H.; Marquard, C.R.; Lange, P.R.; Geserick, C.; Bartosz, C.E.; Chen, C.T.; Slocum, R.D.
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis
New Phytol.
183
117-132
2009
Arabidopsis thaliana
Manually annotated by BRENDA team