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The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
kynurenine formamidase, afmid, formylase, kfase, formamidase i, formamidase ii, arylformamidase, formylkynurenine formamidase,
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formylkynureninase
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formylkynurenine formamidase
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kynurine formamidase
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carboxylic acid amide hydrolysis
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aryl-formylamine amidohydrolase
Also acts on other aromatic formylamines.
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Colonic Neoplasms
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Colorectal Neoplasms
Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level.
Cushing Syndrome
Monitoring type 2 diabetes from volatile faecal metabolome in Cushing's syndrome and single Afmid mouse models via a longitudinal study.
Diabetes Mellitus, Type 2
Monitoring type 2 diabetes from volatile faecal metabolome in Cushing's syndrome and single Afmid mouse models via a longitudinal study.
Glucose Intolerance
Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance.
Neoplasms
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Renal Insufficiency
Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance.
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KFA_HUMAN
303
0
33992
Swiss-Prot
other Location (Reliability: 2)
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3.5.1.9 arylformamidase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
