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5'-nucleotidase deficiency
Inborn errors of purine metabolism: clinical update and therapies.
abc-type polar-amino-acid transporter deficiency
Participation of an extracellular deaminase in amino acid utilization by Neurospora crassa.
Abortion, Spontaneous
Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage.
Acidosis
Involvement of adenosine in depression of synaptic transmission during hypercapnia in isolated spinal cord of neonatal rats.
Acidosis
[Effect of perinatal hypoxia on blood triglycerides and total cholesterol including high density lipoproteins]
Acute Kidney Injury
Serum glycoprotein: glycosyl transferase activity in patients with renal disease.
Adenocarcinoma
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Adenocarcinoma
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Adenocarcinoma of Lung
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Adenocarcinoma of Lung
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Adenocarcinoma of Lung
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK.
adenosine deaminase deficiency
Adenosine as a prostaglandin antagonist. Possible mechanism of the defect in combined immunodeficiency disease due to adenosine deaminase deficiency.
adenosine deaminase deficiency
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
adenosine deaminase deficiency
Cicalese MP, Ferrua F, Castagnaro L, et al. Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. Blood. 2016;128(1):45-54.
adenosine deaminase deficiency
Differential deoxyadenosine toxicity to immature rabbit cartilage in vitro. A model for the chondro-osseous dysplasia of adenosine deaminase deficiency.
adenosine deaminase deficiency
Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency.
adenosine deaminase deficiency
Enzyme replacement therapy with polyethylene glycol-adenosine deaminase in adenosine deaminase deficiency: overview and case reports of three patients, including two now receiving gene therapy.
adenosine deaminase deficiency
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
adenosine deaminase deficiency
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
adenosine deaminase deficiency
The human genes for S-adenosylhomocysteine hydrolase and adenosine deaminase are syntenic on chromosome 20.
adenosine deaminase deficiency
[Molecular pathology of immunological deficiency. Apropos of adenosine deaminase deficiency and nucleoside phosphorylase deficiency]
adenosine deaminase deficiency
[Polyethylene glycol-adenosine deaminase: a new adenosine deaminase deficiency therapy. Value of deoxyadenosine triphosphate determination for therapeutic monitoring]
adenylosuccinate lyase deficiency
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
amidase deficiency
A Competitive Allele-specific Oligomers Polymerase Chain Reaction Assay for the cis Double Mutation in AMPD1 That Is the Major Cause of Myo-adenylate Deaminase Deficiency.
amidase deficiency
Acute intermittent porphyria: rapid molecular diagnosis.
amidase deficiency
Adenosine as a prostaglandin antagonist. Possible mechanism of the defect in combined immunodeficiency disease due to adenosine deaminase deficiency.
amidase deficiency
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
amidase deficiency
Cicalese MP, Ferrua F, Castagnaro L, et al. Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. Blood. 2016;128(1):45-54.
amidase deficiency
Differential deoxyadenosine toxicity to immature rabbit cartilage in vitro. A model for the chondro-osseous dysplasia of adenosine deaminase deficiency.
amidase deficiency
Disruption of the purine nucleotide cycle. A potential explanation for muscle dysfunction in myoadenylate deaminase deficiency.
amidase deficiency
Dissection of the molecular pathology of aspartylglucosaminuria provides the basis for DNA diagnostics and future therapeutic interventions.
amidase deficiency
Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency.
amidase deficiency
Expression of different isoenzymes of adenylate deaminase in cultured human muscle cells. Relation to myoadenylate deaminase deficiency.
amidase deficiency
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
amidase deficiency
Homozygous acute intermittent porphyria: compound heterozygosity for adjacent base transitions in the same codon of the porphobilinogen deaminase gene.
amidase deficiency
Interstitial 5'-nucleotidase stain for frozen biopsy specimens of skeletal muscle. A useful adjunct in the diagnosis of polymyositis.
amidase deficiency
Localization of an adenosine deaminase-binding protein in human kidney.
amidase deficiency
Myoadenylate deaminase deficiency. Functional and metabolic abnormalities associated with disruption of the purine nucleotide cycle.
amidase deficiency
Myotonia congenita and myoadenylate deaminase deficiency: case report.
amidase deficiency
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
amidase deficiency
Possible influence of AMPD1 on cholinergic neurotransmission and sleep.
amidase deficiency
Primary Adenosine Monophosphate Deaminase Deficiency in a Hypotonic Infant.
amidase deficiency
Right ventricular obstructive hypertrophic cardiomyopathy in primary myo-adenylate deaminase deficiency.
amidase deficiency
Severe rhabdomyolysis caused by Plasmodium vivax malaria in the Brazilian Amazon.
amidase deficiency
Standing on the Shoulders of Stem Cell Gene Therapists: History, Hyperbole, and Hope for the Future.
amidase deficiency
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
amidase deficiency
[Adenosine deaminase deficiency with a novel gene mutation].
amidase deficiency
[Glucuronic acid transferase deficiency in children]
amidase deficiency
[Molecular pathology of immunological deficiency. Apropos of adenosine deaminase deficiency and nucleoside phosphorylase deficiency]
amidase deficiency
[The human genome--chromosome 20]
amp deaminase deficiency
Disruption of the purine nucleotide cycle. A potential explanation for muscle dysfunction in myoadenylate deaminase deficiency.
amp deaminase deficiency
Expression of different isoenzymes of adenylate deaminase in cultured human muscle cells. Relation to myoadenylate deaminase deficiency.
amp deaminase deficiency
Immunohistochemical analysis of human skeletal muscle AMP deaminase deficiency. Evidence of a correlation between the muscle HPRG content and the level of the residual AMP deaminase activity.
amp deaminase deficiency
Myoadenylate deaminase deficiency. Functional and metabolic abnormalities associated with disruption of the purine nucleotide cycle.
Anemia
E-ADA activity in erythrocytes of lambs experimentally infected with Haemonchus contortus and its possible functional correlations with anemia.
Angioedema
Hereditary C1 inhibitor deficiency is associated with high spontaneous amidase activity.
Angioedemas, Hereditary
Hereditary C1 inhibitor deficiency is associated with high spontaneous amidase activity.
Anthrax
The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.
Arthritis
A synovial amidase acting on tissue kallikrein-selective substrate in clinical and experimental arthritis.
Arthritis
An Important Role for N-Acylethanolamine Acid Amidase in the Complete Freund's Adjuvant Rat Model of Arthritis.
Arthritis
Effect of quercetin on E-NTPDase/E-ADA activities and cytokine secretion of complete Freund adjuvant-induced arthritic rats.
Arthritis
Free and nanoencapsulated vitamin D3 : effects on E-NTPDase and E-ADA activities in an animal model with induced arthritis.
Arthritis
Inflammatory properties of peptidoglycan are decreased after degradation by human N-acetylmuramyl-L-alanine amidase.
Arthritis, Experimental
[Therapeutic effect of gene silencing peptidyl arginine deaminase 4 on pulmonary interstitial lesions induced by collagen-induced arthritis mice].
Arthritis, Rheumatoid
A tissue kallikrein in the synovial fluid of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Amidase and peptidase activities of polyclonal immunoglobulin G present in the sera of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Anti-peptidyl-arginine deaminase 3 (PAD3) antibodies as a promising marker to measure joint damage in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.
Aspartylglucosaminuria
Characterization of the mutation responsible for aspartylglucosaminuria in three Finnish patients. Amino acid substitution Cys163----Ser abolishes the activity of lysosomal glycosylasparaginase and its conversion into subunits.
Aspartylglucosaminuria
Deletion of the C-terminal end of aspartylglucosaminidase resulting in a lysosomal accumulation disease: evidence for a unique genomic rearrangement.
Aspartylglucosaminuria
Dissection of the molecular pathology of aspartylglucosaminuria provides the basis for DNA diagnostics and future therapeutic interventions.
Aspartylglucosaminuria
Large-scale purification of human aspartylglucosaminidase: utilization of exceptional sodium dodecyl sulfate resistance.
Aspartylglucosaminuria
The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria.
Asthma
[Carbamoyl ornithine transferase, arginase and cobalt-activated acylase in patients during asthma attacks or patients with respiratory failure]
Atherosclerosis
Expression of Bace1 is positive with the progress of atherosclerosis and formation of foam cell.
Atherosclerosis
Vascular extracellular adenosine metabolism in mice correlates with susceptibility to atherosclerosis.
Autoimmune Diseases
Regulation of Activation Induced Deaminase (AID) by Estrogen.
Bacterial Infections
A peptidoglycan recognition protein from Sciaenops ocellatus is a zinc amidase and a bactericide with a substrate range limited to Gram-positive bacteria.
Bacterial Infections
The Drosophila Amidase PGRP-LB Modulates the Immune Response to Bacterial Infection.
Bradycardia
Effect of adenosine on heart rate in isolated muskrat and guinea pig hearts.
Brain Neoplasms
Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors.
Brucellosis
Occurrence of oxidative stress in dairy cows seropositives for Brucella abortus.
Burkitt Lymphoma
Burkitt's lymphoma in a patient with adenosine deaminase deficiency-severe combined immunodeficiency treated with polyethylene glycol-adenosine deaminase.
Carcinogenesis
Association between targeted somatic mutation (TSM) signatures and HGS-OvCa progression.
Carcinogenesis
Cobalt-activated acylase (AA-Co) activity in experimental liver carcinogenesis in rats. Part I. Chronic poisoning by dimethylaminoazobenzene.
Carcinogenesis
Cobalt-activated acylase (AA-Co) activity in experimental liver carcinogenesis in rats. Part II. Chronic poisoning with carbon tetrachloride (CCl4).
Carcinogenesis
DNA deamination in immunity.
Carcinogenesis
Regulation of Activation Induced Deaminase (AID) by Estrogen.
Carcinogenesis
Role of activation-induced cytidine deaminase in the development of oral squamous cell carcinoma.
Carcinoma
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Carcinoma
Blood serum peptidases in patients with ovarian carcinoma treated with Ledakrin.
Carcinoma
Cobalt-activated acylase and aminoacylase I in human malignant tumors.
Carcinoma
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Carcinoma
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Carcinoma
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Carcinoma
Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities.
Carcinoma
In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3.
Carcinoma
Purification and properties of acylase from Ehrlich ascites carcinoma cells.
Carcinoma
Serum cobalt-activated acylase in cervical carcinoma during radiotherapy.
Carcinoma
Two approaches that increase the activity of analogs of adenine nucleosides in animal cells.
Carcinoma, Ehrlich Tumor
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Carcinoma, Ehrlich Tumor
Deoxycytidylic acid deaminase in Ehrlich ascites tumor cells.
Carcinoma, Hepatocellular
Heme-biosynthetic enzyme activities and porphyrin accumulation in normal liver and hepatoma cell lines of rat.
Carcinoma, Hepatocellular
Nucleotide interconversions. IV. Activities of deoxycytidylate deaminase and thymidylate synthetase in normal rat liver and hepatomas.
Carcinoma, Hepatocellular
Origin of increased deoxycytidine excretion into urine of rats bearing Yoshida ascites sarcoma.
Carcinoma, Hepatocellular
Serum and host liver activities of glycosidases and sialyltransferases in animals bearing transplantable tumors.
Carcinoma, Hepatocellular
The comparative enzymology and cell origin of rat hepatomas. I. Deoxycytidylate deaminase and thymine degradation.
Carcinoma, Hepatocellular
The intra-cellular distribution of cathepsin, benzoylarginine amidase and leucine amidase activities in normal rat tissues and primary rat hepatoma.
Carcinoma, Hepatocellular
[Biochemical and functional characteristics of thymus and spleen lymphocytes in C3HA mice during the growth of hepatoma 22 and after immunization with sheep erythrocytes]
Carcinoma, Lewis Lung
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Carcinoma, Squamous Cell
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Cardiomyopathies
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.
Cardiomyopathy, Hypertrophic
Right ventricular obstructive hypertrophic cardiomyopathy in primary myo-adenylate deaminase deficiency.
Cardiotoxicity
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.
Celiac Disease
Abnormal anandamide metabolism in celiac disease.
Chagas Disease
E-NTPDase and E-ADA activities are altered in lymphocytes of patients with indeterminate form of Chagas' disease.
Chemical and Drug Induced Liver Injury
Serum cobalt-activated acylase and gamma-glutamyl transpeptidase activities in toxic hepatitis.
Cholera
Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals.
Coccidiosis
Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis.
Colitis
Is ulcerative colitis a reversible disease?: Commentary on "Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation" BBI-D-16-00318R1.
Colitis
N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis.
Colitis, Ulcerative
Is ulcerative colitis a reversible disease?: Commentary on "Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation" BBI-D-16-00318R1.
Colitis, Ulcerative
Neutrophil extracellular traps-associated protein peptidyl arginine deaminase 4 immunohistochemical expression in ulcerative colitis and its association with the prognostic predictors.
Colonic Neoplasms
Effects of a hybrid recombinant human alpha interferon (A/D) on in vitro cytotoxicity and in vivo localization of monoclonal antibody L6-cytosine deaminase conjugate in a colon cancer model.
Colonic Neoplasms
Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study.
Colonic Neoplasms
The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model.
Colonic Neoplasms
[The expression of Tn and S-Tn antigens in cancer and pre-malignant lesion of colorectal tissues by enzyme immunohistochemical method]
Colorectal Neoplasms
Cell Death Mechanisms Induced by CLytA-DAAO Chimeric Enzyme in Human Tumor Cell Lines.
Colorectal Neoplasms
[Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice].
Colorectal Neoplasms
[The expression of Tn and S-Tn antigens in cancer and pre-malignant lesion of colorectal tissues by enzyme immunohistochemical method]
Communicable Diseases
Molecular epidemiology and diagnosis of PBG deaminase gene defects in acute intermittent porphyria.
Contracture
Single-cell measurements of purine release using a micromachined electroanalytical sensor.
Coproporphyria, Hereditary
Alterations in the activity of enzymes of haem biosynthesis in lead poisoning and acute hepatic prophyria.
Coronary Artery Disease
Augmented hyperaemia and reduced tissue injury in response to ischaemia in subjects with the 34C > T variant of the AMPD1 gene.
Coronary Artery Disease
Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene.
Craniocerebral Trauma
Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment--part I.
Craniocerebral Trauma
TEMPORAL WINDOW OF METABOLIC BRAIN VULNERABILITY TO REPEAT CONCUSSIONS: MITOCHONDRIAL-RELATED IMPAIRMENT-PART I.
Crush Syndrome
Activity of enzymes of adenyline compounds metabolism during crush and decompression of muscle tissue. Part I. Adenylate deaminase activity at experimental crush syndrome.
Crush Syndrome
Activity of enzymes of adenyline compounds metabolism during crush and decompression of muscle tissue. Part II. Adenosine deaminase activity at experimental crush syndrome.
Dehydration
Effects of plant growth-promoting rhizobacteria strains producing ACC deaminase on photosynthesis, isoprene emission, ethylene formation and growth of Mucuna pruriens (L.) DC. in response to water deficit.
Dehydration
Molecular and practical aspects of the enzymatic properties of human serum albumin and of albumin-ligand complexes.
Dermatitis, Atopic
Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency?
Dermatitis, Atopic
Localization of sphingomyelinase in lesional skin of atopic dermatitis patients.
Diabetes Mellitus
Diagnostic Value of Adenosine Deaminase and Its Isoforms in Type II Diabetes Mellitus.
Diabetes Mellitus, Type 1
Increased tissue kallikrein amidase activity in urine of patients with type 1 diabetes under insulin therapy, and in those with gestational diabetes mellitus not under insulin therapy.
Diabetes Mellitus, Type 1
Is there a role of ACP1-ADA1 genetic complex in immune reaction? Association with T1D and with past malarial morbidity.
Diabetes, Gestational
Increased tissue kallikrein amidase activity in urine of patients with type 1 diabetes under insulin therapy, and in those with gestational diabetes mellitus not under insulin therapy.
Digestive System Diseases
Cobalt-activated acylase in human serum. Occurrence in hepatobiliary diseases.
Digestive System Diseases
[Serum gamma glutamyl transpeptidase in hepatobiliary diseases. Comparison with alkaline phosphatase and aryl amidase]
double-stranded rna adenine deaminase deficiency
Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes.
Drug-Related Side Effects and Adverse Reactions
A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine.
Eczema
[The dynamics of the kallikrein-kinin system indices in patients with eczema vera during treatment by the laser photophoresis method with ortofen]
Encephalomyelitis
Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda-/- and Ung-/- Mice.
Encephalomyelitis
N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.
Encephalomyelitis, Autoimmune, Experimental
N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.
Fatty Liver
Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis.
Gastrointestinal Diseases
Isozyme variations of serum alkaline phosphatase and naphthyl amidase in biliary and gastrointestinal disease.
Genetic Diseases, Inborn
RNA editing of BFP, a point mutant of GFP, using artificial APOBEC1 deaminase to restore the genetic code.
Glioblastoma
Cell Death Mechanisms Induced by CLytA-DAAO Chimeric Enzyme in Human Tumor Cell Lines.
Glioblastoma
Double suicide gene therapy using human neural stem cells against glioblastoma: double safety measures.
Glioblastoma
Molecular mechanism of inhibition of acid ceramidase by carmofur.
Glioma
Apoptosis induction with 5-fluorocytosine/cytosine deaminase gene therapy for human malignant glioma cells mediated by adenovirus.
Glioma
Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes.
Glioma
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist.
Glioma
In vivo efficacy and toxicity of 5-fluorocytosine/cytosine deaminase gene therapy for malignant gliomas mediated by adenovirus.
Glioma
Nuclear distribution of porphobilinogen deaminase (PBGD) in glioma cells: a regulatory role in cancer transformation?
Gliosarcoma
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity.
Granuloma
Management of inflammation: lipid peroxide as a parameter for a better understanding of inflammatory processes.
Granulomatous Disease, Chronic
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side.
Heart Failure
Human Tissue Kallikrein Activity in Angiographically Documented Chronic Stable Coronary Artery Disease.
Heart Failure
The adenosine deaminase gene polymorphism is associated with chronic heart failure risk in Chinese.
Heart Failure, Systolic
The amidase activity of human tissue kallikrein is significantly lower in the urine of patients with systolic heart failure.
Hepatic Encephalopathy
Urease and deaminase activities of fecal bacteria in hepatic coma.
Hepatitis
A genetic study of serum levels of cobalt-activated acylase among susceptible, resistant and semiresistant strains of mice with experimental viral hepatitis.
Hepatitis
Activity of cobalt-activated acylase and Australia antigen (HBAg) in children suffering from viral hepatitis.
Hepatitis
Cobalt-activated acylase in serum of patients with viral hepatitis.
Hepatitis
Crystallization and X-ray diffraction analysis of the Trp/amber editing site of hepatitis delta virus (+)RNA: a case of rational design.
Hepatitis
Dics-test for cobalt-activated acylase activity and its use for early diagnosis of viral hepatitis.
Hepatitis
Enzyme-linked immunosorbent assay (ELISA) of acylase in serum of patients with viral hepatitis.
Hepatitis
Fluorimetric determination and enzyme immunoassay of cobalt-activated acylase in serum of patients with viral hepatitis.
Hepatitis
Molecular forms of cobalt-activated acylase in human tissues and serum of patients with viral hepatitis.
Hepatitis
Purification of cobalt-activated acylase by affinity chromatography.
Hepatitis
RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase.
Hepatitis
Serum cobalt-activated acylase activity as a new enzymatic test in viral hepatitis.
Hepatitis
The behaviour of glycylaminopeptidase activity in the blood serum of patients with viral hepatitis and the comparison with cobalt-activated acylase activity.
Hepatitis
[Activity of cobalt-activated acylase and guanase in the serum of patients with viral hepatitis]
Hepatitis
[Activity of serum cobalt-activated acylase in viral hepatitis]
Hepatitis
[Behavior of cobalt-activated acylase in blood serum of patients with viral hepatitis and myocardial infarct]
Hepatitis
[Cobalt-activated acylase activity test as applied in the diagnosis of viral hepatitis]
Hepatitis
[Cobalt-activated acylase determination in serum as a new enzyme test in viral hepatitis]
Hepatitis
[Diagnostic value of cobalt-activated acylase in viral hepatitis and its complications]
Hepatitis
[Diagnostic value of cobalt-activated acylase in viral hepatitis. Comparative study including 7 other enzymes]
Hepatitis
[Serum cobalt-activated acylase in patients with viral hepatitis, liver cirrhosis and liver neoplasms]
Hepatitis
[Serum cobalt-activated acylase in subjects exposed to family members with viral hepatitis]
Hepatitis
[Simplified method of determination of blood acylase activity as a new test for preclinical diagnosis of viral hepatitis]
Hepatitis B
Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.
Hepatitis C
Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.
Hepatitis, Chronic
[Diagnostic value of determination of cobalt-activated acylase in acute and chronic hepatitis]
Herpes Simplex
Activity of (+)-cyclaradine (Sch 31172) against herpes simplex virus in vitro and in vivo.
Herpes Simplex
Analysis of deoxycytidine (dC) deaminase activity in herpes simplex virus-infected or HSV TK-transformed cells: association with mycoplasma contamination but not with virus infection.
Herpes Simplex
Antiherpes virus activity and effect on deoxyribonucleoside triphosphate pools of (E)-5-(2-bromovinyl)-2'-deoxycytidine in combination with deaminase inhibitors.
Herpes Simplex
Antiviral activity of an adenosine deaminase inhibitor: decreased replication of herpes simplex virus.
Herpes Simplex
Deoxyribonucleoside triphosphate pools of herpes simplex virus infected cells: the influence of selective antiherpes agents and the role of the deaminase pathway.
Herpes Simplex
Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo.
Herpes Simplex
Erythro-9-(2-hydroxy-3-nonyl)adenine as a specific inhibitor of herpes simplex virus replication in the presence and absence of adenosine analogues.
Herpes Simplex
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity.
Herpes Simplex
Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA.
Herpes Zoster
Profile analysis of expressed sequence tags derived from the ovary of tilapia, Oreochromis mossambicus
Herpes Zoster
Some effects of zona pellucida glycoproteins and sulfated polymers on the autoactivation of boar sperm proacrosin and activity of beta-acrosin.
HIV Infections
Disruption of the gamma c cytokine network in T cells during HIV infection.
Hyperalgesia
Endogenous opioid and cannabinoid systems modulate the muscle pain: A pharmacological study into the peripheral site.
Hyperalgesia
Free and nanoencapsulated vitamin D3 : effects on E-NTPDase and E-ADA activities in an animal model with induced arthritis.
Hypercholesterolemia
Hypercholesterolemia and Ecto-enzymes of Purinergic System: Effects of Paullinia cupana.
Hypercholesterolemia
Vascular extracellular adenosine metabolism in mice correlates with susceptibility to atherosclerosis.
Hyperemia
Possible role for adenosine in local regulation of absorptive hyperemia in rat intestine.
Hyperglycemia
Increased tissue kallikrein amidase activity in urine of patients with type 1 diabetes under insulin therapy, and in those with gestational diabetes mellitus not under insulin therapy.
Hyperlipidemias
Vascular extracellular adenosine metabolism in mice correlates with susceptibility to atherosclerosis.
Hypersensitivity
Human melanoma cells sensitive to deoxyadenosine and deoxyinosine.
Hypersensitivity
Mutations in Arabidopsis fatty acid amide hydrolase reveal that catalytic activity influences growth but not sensitivity to abscisic acid or pathogens.
Hypersensitivity
Transcription factor GATA-1 and Down syndrome leukemogenesis.
Hypertension
Human Tissue Kallikrein Activity in Angiographically Documented Chronic Stable Coronary Artery Disease.
Hypertriglyceridemia
Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor.
Infections
A T4-phage deoxycytidylate deaminase mutant that no longer requires deoxycytidine 5'-triphosphate for activation.
Infections
Analysis of deoxycytidine (dC) deaminase activity in herpes simplex virus-infected or HSV TK-transformed cells: association with mycoplasma contamination but not with virus infection.
Infections
Antiviral potency of APOBEC proteins does not correlate with cytidine deamination.
Infections
B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function.
Infections
Biochemical and Biological Studies of Mouse APOBEC3.
Infections
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.
Infections
Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome.
Infections
Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B.
Infections
Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection.
Infections
Preclinical assessment of the treatment of second-stage african trypanosomiasis with cordycepin and deoxycoformycin.
Infections
Production, characterization, and powder preparation of quorum quenching acylase AiiO for pathogen control.
Infections
Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.
Infections
PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection.
Infections
Quorum quenching acylase reduces the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model.
Infections
Rapid detection of urinary tract infection caused by Escherichia coli or Proteeae species.
Infections
Rapid identification of micro-organisms from urinary tract infections by beta-glucuronidase, phenylalanine deaminase, cytochrome oxidase and indole tests on isolation media.
Infections
Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity.
Infections
T4-phage deoxycytidylate deaminase is a metalloprotein containing two zinc atoms per subunit.
Infections
The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia.
Infections
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
Infections
[Antibody enzymes in Helicobacter pylori-associated infection]
Infections
[Rapid method for identifying Escherichia coli and species of the Proteeae tribe in urine]
Infectious Mononucleosis
[Serum activity of cobalt-activated acylase in infectious mononucleosis]
Infertility
Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral Fatty Acid amide hydrolase activity.
Infertility, Female
Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage.
Infertility, Male
A genome-wide identification and analysis of the DYW-deaminase genes in the pentatricopeptide repeat gene family in cotton (Gossypium spp.).
Influenza, Human
Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine Antigens.
Influenza, Human
The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization.
Insulin Resistance
Berberine improves free-fatty-acid-induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator-activated receptor gamma and fatty acid transferase expressions.
Insulin Resistance
Surgical site peptidylarginine deaminase 4 (PAD4), a biomarker of NETosis, correlates with insulin resistance in total joint arthroplasty patients: A preliminary report.
Intellectual Disability
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Jaundice, Neonatal
Enzyme variability and neonatal jaundice. The role of adenosine deaminase and acid phosphatase.
Keratoconjunctivitis
[Correlation between biochemical features and pathogenicity of Shigella. IV. Threonine deaminase of Shigella strains producing and not producing keratoconjunctivitis in guinea pigs]
Kidney Diseases
Localization of an adenosine deaminase-binding protein in human kidney.
Laryngeal Neoplasms
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Leukemia
A second N-acylethanolamine hydrolase in mammalian tissues.
Leukemia
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Leukemia
APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair.
Leukemia
DNA deamination mediates innate immunity to retroviral infection.
Leukemia
Effect of tetrahydrouridine and deoxytetrahydrouridine on the interaction between 2'-deoxycytidine and 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
Leukemia
Effects of murine viral leukemia on spleen nucleoside deaminase: purification and properties of the enzyme from leukemic spleen.
Leukemia
Enzyme activity in mice with transplantable leukemia.
Leukemia
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia
Nucleoside deaminase activity in viral leukemia.
Leukemia
Serum and host liver activities of glycosidases and sialyltransferases in animals bearing transplantable tumors.
Leukemia
Serum cobalt-activated acylase as a marker of transplantable leukemia in mice.
Leukemia
[Activity of adenosine deaminase in the blood serum of children. II. Activity of adenosine deaminase in leukemias in children.]
Leukemia
[Chemotherapy of acute leukemia with cyclocytidine, with special reference to serum ara-C deaminase activity (author's transl)]
Leukemia L1210
Deamination rates of 1-beta-D-arabinofuranosylcytosine, deoxycytidine and 5-methyl-2'-deoxycytidine in seven hematopoietic cell lines.
Leukemia, Erythroblastic, Acute
Hemin enhances the sensitivity of erythroleukemia cells to 1-beta-D-arabinofuranosylcytosine by both activation of deoxycytidine kinase and reduction of cytidine deaminase activity.
Leukemia, Lymphocytic, Chronic, B-Cell
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Quantification of Bcr-Abl transcripts in chronic myelogenous leukemia (CML) using standardized, internally controlled, competitive differential PCR (CD-PCR).
Leukemia, Myeloid
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Leukemia, Myeloid, Acute
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia, Myeloid, Acute
[Effect of ADAR1 on the development of MLL-AF9 induced murine AML].
Leukemia-Lymphoma, Adult T-Cell
Characterization of AtlL, a bifunctional autolysin of Staphylococcus lugdunensis with N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities.
Leukopenia
Studies of cytomegalovirus infection in renal allograft recipients.
Liver Cirrhosis
Cytidine-5'-monophosphate-N-acetylneuraminic acid. Asialoglycoprotein sialic acid transferase activity in liver and serum of patients with juvenile hepatic cirrhosis and alpha-1-antitrypsin deficiency.
Liver Cirrhosis
[Serum cobalt-activated acylase in patients with viral hepatitis, liver cirrhosis and liver neoplasms]
Liver Diseases
Activity of acylase in liver diseases.
Liver Diseases
[Activity of cobalt-activated acylase in liver tissue in patients with acute and chronic liver diseases]
Liver Neoplasms
Prolonged stability and sustained prodrug cell killing activity using receptor-mediated delivery of malarial circumsporozoite-cytosine deaminase fusion protein into liver cancer cells.
Liver Neoplasms
[Serum cobalt-activated acylase in patients with viral hepatitis, liver cirrhosis and liver neoplasms]
Lung Neoplasms
[Combination of ARE and HRE cis- Regulatory Elements Elevates the Activity of Tumor-Specific hTERT Promoter].
Lymphadenitis
[Study of the amidase properties of Mycobacterium strains isolated in humans with nontubercular adenitis]
Lymphoma
Further insights into the regulation of human FAAH by progesterone and leptin implications for endogenous levels of anandamide and apoptosis of immune and neuronal cells.
Lymphoma
Serum cobalt-activated acylase as a marker of transplantable leukemia in mice.
Lymphoma, Follicular
Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.
Lymphoma, T-Cell
CD26 in T-cell lymphomas: a potential clinical role?
Lymphoma, T-Cell, Cutaneous
Purine pathway enzymes in the circulating malignant cells of patients with cutaneous T-cell lymphoma.
Lysosomal Storage Diseases
Dissection of the molecular pathology of aspartylglucosaminuria provides the basis for DNA diagnostics and future therapeutic interventions.
Lysosomal Storage Diseases
Large-scale purification of human aspartylglucosaminidase: utilization of exceptional sodium dodecyl sulfate resistance.
Malabsorption Syndromes
[Acylase activity of human small intestinal mucosa in malabsorption syndrome]
Melanoma
ADAR1 regulates melanoma cell invasiveness by controlling beta3-integrin via microRNA-30 family members.
Melanoma
Cell surface antigens of human melanocytes and melanoma. Expression of adenosine deaminase binding protein is extinguished with melanocyte transformation.
Melanoma
Human melanoma cells sensitive to deoxyadenosine and deoxyinosine.
Melanoma
Molecular mechanism of inhibition of acid ceramidase by carmofur.
Melanoma
Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells.
Melanoma, Experimental
A safe, effective in vivo gene therapy for melanoma using tyrosinase promoter-driven cytosine deaminase gene.
Mesothelioma, Malignant
Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma.
Multiple Sclerosis
Antinociceptive Profile of ARN19702, (2-Ethylsulfonylphenyl)-[(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpiperazin-1-yl]methanone, a Novel Orally Active N-Acylethanolamine Acid Amidase Inhibitor, in Animal Models.
Multiple Sclerosis
Inhibition of N-acylethanolamine-hydrolyzing acid amidase reduces T cell infiltration in a mouse model of multiple sclerosis.
Multiple Sclerosis
N-Acylethanolamine Acid Amidase contributes to disease progression in a mouse model of multiple sclerosis.
Muscle Cramp
Clinical heterogeneity and molecular mechanisms in inborn muscle AMP deaminase deficiency.
Muscular Diseases
Clinical heterogeneity and molecular mechanisms in inborn muscle AMP deaminase deficiency.
Myalgia
Clinical heterogeneity and molecular mechanisms in inborn muscle AMP deaminase deficiency.
Myalgia
Primary Adenosine Monophosphate Deaminase Deficiency in a Hypotonic Infant.
Myocardial Infarction
[Behavior of cobalt-activated acylase in blood serum of patients with viral hepatitis and myocardial infarct]
Myoma
Cobalt-activated acylase from human uterine myoma.
Myosarcoma
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Myotonia Congenita
Myotonia congenita and myoadenylate deaminase deficiency: case report.
Neoplasm Metastasis
Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells.
Neoplasm Metastasis
Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors.
Neoplasm Metastasis
The dietary flavonoid apigenin enhances the activities of the anti-metastatic protein CD26 on human colon carcinoma cells.
Neoplasms
A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival.
Neoplasms
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Neoplasms
Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.
Neoplasms
Acylase activity of ascites tumour cells on dichloroacetyl derivatives of amino-acids.
Neoplasms
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.
Neoplasms
ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism.
Neoplasms
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Neoplasms
AIDing the immune system-DIAbolic in cancer.
Neoplasms
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation.
Neoplasms
Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamide.
Neoplasms
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.
Neoplasms
Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine.
Neoplasms
Biodistribution, tumor detection and radiation dosimetry of F-18 5-Fluoro-2'-Deoxycytidine (18F-FdCyd) with Tetrahydrouridine in solid tumors.
Neoplasms
Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor.
Neoplasms
Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B.
Neoplasms
Clinical utility of different tumor markers in breast cancer and gynecological malignancies.
Neoplasms
Cobalt-activated acylase and aminoacylase I in human malignant tumors.
Neoplasms
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Neoplasms
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.
Neoplasms
Correlation of serum, tumor, and liver serum glycoprotein: N-acetylneuraminic acid transferase activity with growth of the R3230AC mammary tumor in rats and relationship of the serum activity to tumor burden.
Neoplasms
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Neoplasms
Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif.
Neoplasms
Deoxycytidylic acid deaminase in Ehrlich ascites tumor cells.
Neoplasms
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue.
Neoplasms
Differential killing of mismatch repair-deficient and -proficient cells: towards the therapy of tumors with microsatellite instability.
Neoplasms
Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.
Neoplasms
DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.
Neoplasms
Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo.
Neoplasms
Effects of orthotopic implantation of rat prostate tumour cells upon components of the N-acylethanolamine and monoacylglycerol signalling systems: an mRNA study.
Neoplasms
Endocannabinoids as endometrial inflammatory markers in lactating Holstein cows.
Neoplasms
Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells.
Neoplasms
Enhancement of the antitumor activity of arabinofuranosyladenine of 2'-deoxycoformycin.
Neoplasms
Evaluation of different primer sets for the rapid diagnosis of tuberculosis.
Neoplasms
Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo.
Neoplasms
Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug.
Neoplasms
Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness.
Neoplasms
Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B.
Neoplasms
Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination.
Neoplasms
Imaging of branched chain amino acid metabolism in tumors with hyperpolarized (13)C ketoisocaproate.
Neoplasms
Immunity through DNA deamination.
Neoplasms
In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3.
Neoplasms
Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.
Neoplasms
Kinase and deaminase activity in a variety of subcutaneous mouse tumors.
Neoplasms
Lipopolysaccharide enhances ADAR2 which drives Hirschsprung's disease by impairing miR-142-3p biogenesis.
Neoplasms
Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells.
Neoplasms
Metabolism of 1-beta-D-arabinofuranosyl-5-azacytosine and incorporation into DNA of human T-lymphoblastic cells (Molt-4).
Neoplasms
Metabolism of endocannabinoids and related N-acylethanolamines: Canonical and alternative pathways.
Neoplasms
Molecular mechanism of inhibition of acid ceramidase by carmofur.
Neoplasms
Molecular model linking Th2 polarized M2 Tumor Associated Macrophages (TAMs) with deaminase-mediated cancer progression mutation signatures.
Neoplasms
Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice.
Neoplasms
Mutation in the Drosophila melanogaster adenosine receptor gene selectively decreases the mosaic hyperplastic epithelial outgrowth rates in wts or dco heterozygous flies.
Neoplasms
Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis.
Neoplasms
New players in the fatty acyl ethanolamide metabolism.
Neoplasms
New scoring system using tumor markers in diagnosing patients with moderate pericardial effusions.
Neoplasms
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.
Neoplasms
Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks.
Neoplasms
Origin of increased deoxycytidine excretion into urine of rats bearing Yoshida ascites sarcoma.
Neoplasms
p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.
Neoplasms
Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.
Neoplasms
Radiation, pool size and incorporation studies in mice with 5-chloro-2'-deoxycytidine.
Neoplasms
Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.
Neoplasms
RNA Editing Dynamically Rewrites the Cancer Code.
Neoplasms
Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer.
Neoplasms
Roles of APOBEC3 in hepatitis B virus (HBV) infection and hepatocarcinogenesis.
Neoplasms
Stem and progenitor cell-mediated tumor selective gene therapy.
Neoplasms
Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth.
Neoplasms
The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase.
Neoplasms
The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Neoplasms
The dietary flavonoid apigenin enhances the activities of the anti-metastatic protein CD26 on human colon carcinoma cells.
Neoplasms
The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.
Neoplasms
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Neoplasms
Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.
Neoplasms
Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.
Neoplasms
[Action of deoxyadenosine on nucleic acid synthesis by tumor cells in the presence of a deaminase inhibitor]
Neoplasms
[Anticancer activity of N-(phenylacetyl) doxorubicin combined with folate-targeted PGA]
Neoplasms
[Combination of ARE and HRE cis- Regulatory Elements Elevates the Activity of Tumor-Specific hTERT Promoter].
Neoplasms
[Increase of the functional activity of natural killers under the effects of the pharmacological correction of the sympathoadrenal system state in patients with lung cancer]
Neoplasms
[The modification of the catalytic activity of mitochondrial monoaminoxidase and the suppression of the growth of experimental brain tumors]
Nephrotic Syndrome
Serum glycoprotein: glycosyl transferase activity in patients with renal disease.
Nervous System Diseases
Acute intermittent porphyria: laboratory diagnosis by molecular methods.
Neurilemmoma
Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo.
Neuroblastoma
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist.
Neuroblastoma
Further insights into the regulation of human FAAH by progesterone and leptin implications for endogenous levels of anandamide and apoptosis of immune and neuronal cells.
Neuroblastoma
Inhibitors of arachidonoyl ethanolamide hydrolysis.
Neuroblastoma
The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.
Neuroinflammatory Diseases
N-Palmitoylethanolamine-oxazoline (PEA-OXA) as a new therapeutic strategy to control neuroinflammation: neuroprotective effects in experimental models of spinal cord and brain injury.
Nocardia Infections
[The etiology of streptothricosis in Chad zebus. Nocardiosis or mycobacteriosis? 3. Amidase activity]
Obesity
Hyperactive hypothalamus, motivated and non-distractible chronic overeating in ADAR2 transgenic mice.
Obesity
Surgical site peptidylarginine deaminase 4 (PAD4), a biomarker of NETosis, correlates with insulin resistance in total joint arthroplasty patients: A preliminary report.
Osteoarthritis
A tissue kallikrein in the synovial fluid of patients with rheumatoid arthritis.
Osteoarthritis
N-Acylethanolamine acid amidase (NAAA) inhibitor F215 as a novel therapeutic agent for osteoarthritis.
Otitis Media
Role of the bacterial cell wall in middle ear inflammation caused by Streptococcus pneumoniae.
Ovarian Neoplasms
[Killing effect of adenovirus mediated fusion gene cytosine and deaminase uracil phosphoribosyl transferase directed by glutathione S-transferase P1 promoter on cisplatin-resistant ovarian cancer cells in vitro]
Pancreatic Diseases
[Determination of plasma amidase activity in pancreatic diseases]
Pancreatic Neoplasms
Oral bacteria in pancreatic cancer: mutagenesis of the p53 tumour suppressor gene.
Pancreatic Neoplasms
Study of apoptosis induction and deoxycytidine kinase/cytidine deaminase modulation in the synergistic interaction of a novel ceramide analog and gemcitabine in pancreatic cancer cells.
Pancreatitis
A nonpancreatic source of the proteolytic-enzyme amidase and bacteriology in experimental acute pancreatitis.
Pancreatitis
Increased plasma proteolytic activity due to arginine amidase in patients with pancreatitis.
Pancreatitis
Role of the protease-antiprotease balance in peritoneal exudate during acute pancreatitis.
Pancreatitis
Studies on the ascites fluid of acute pancreatitis in man.
Pancreatitis
[Benzoylarginine amidase activity of blood serum and plasma in acute pancreatitis]
Pancreatitis, Acute Necrotizing
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
Parkinson Disease
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism.
Pericarditis
New scoring system using tumor markers in diagnosing patients with moderate pericardial effusions.
Peritonitis
Diagnostic value of ascites gamma interferon levels in tuberculous peritonitis. Comparison with adenosine deaminase activity.
Peritonitis
[A case of a young woman with tuberculous peritonitis diagnosed owing to high value of ADA]
Photophobia
[Nicotinamidase and the so-called pyrazinamidase in mycobacteria; the simultaneous occurrence of both activites (author's transl)]
Plague
[Determination of asparagine deaminase activity in identifying cultures of the causative agents of plague and pseudotuberculosis]
Plant Diseases
Metagenomic Analysis of the Bacterial Community Associated with the Taproot of Sugar Beet.
Plasmacytoma
Enzyme activity in mice with transplantable leukemia.
Plasmacytoma
Serum cobalt-activated acylase as a marker of transplantable leukemia in mice.
Pleural Effusion
Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting.
Pleural Effusion
Diagnostic tools in tuberculous pleurisy: a direct comparative study.
Pleural Effusion
Immunobiology of pleural inflammation: potential implications for pathogenesis, diagnosis and therapy.
Pleural Effusion
The pleural fluid lactate dehydrogenase/adenosine deaminase ratio differentiates between tuberculous and parapneumonic pleural effusions.
Pleurisy
Evaluation of different primer sets for the rapid diagnosis of tuberculosis.
Pleurisy
[Lymphocyte activation in tuberculous pleuritis . Correlation with adenosine deaminase (ADA), peripheral blood lymphocytes, T cell receptor subfamilies, radiographic extension and levels of Il-6 and soluble Il-2 receptor]
porphobilinogen synthase deficiency
Hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: studies in lymphocytes and erythrocytes.
Porphyria, Acute Intermittent
Acute intermittent porphyria caused by a C----T mutation that produces a stop codon in the porphobilinogen deaminase gene.
Porphyria, Acute Intermittent
Acute intermittent porphyria in Sweden. Molecular, functional and clinical consequences of some new mutations found in the porphobilinogen deaminase gene.
Porphyria, Acute Intermittent
Acute intermittent porphyria in The Netherlands. Heterogeneity of the enzyme porphobilinogen deaminase.
Porphyria, Acute Intermittent
Acute intermittent porphyria with central pontine myelinolysis and cortical laminar necrosis.
Porphyria, Acute Intermittent
Acute intermittent porphyria: laboratory diagnosis by molecular methods.
Porphyria, Acute Intermittent
Acute intermittent porphyria: rapid molecular diagnosis.
Porphyria, Acute Intermittent
Circadian rhythms in acute intermittent porphyria--a pilot study.
Porphyria, Acute Intermittent
Genetic heterogeneity of the porphobilinogen deaminase gene in Swedish families with acute intermittent porphyria.
Porphyria, Acute Intermittent
High frequency of mutations in exon 10 of the porphobilinogen deaminase gene in patients with a CRIM-positive subtype of acute intermittent porphyria.
Porphyria, Acute Intermittent
High prevalence of intermittent acute porphyria in a psychiatric patient population.
Porphyria, Acute Intermittent
Influence of age and gender on the clinical expression of acute intermittent porphyria based on molecular study of porphobilinogen deaminase gene among Swiss patients.
Porphyria, Acute Intermittent
LT-11-056 liver transplantation for acute intermittent porphyria is complicated by a high rate of hepatic artery thrombosis.
Porphyria, Acute Intermittent
Molecular analysis of porphobilinogen (PBG) deaminase gene mutations in acute intermittent porphyria: first study in patients of Slavic origin.
Porphyria, Acute Intermittent
Molecular heterogeneity of acute intermittent porphyria: identification of four additional mutations resulting in the CRIM-negative subtype of the disease.
Porphyria, Acute Intermittent
Mutation hotspots in the human porphobilinogen deaminase gene: recurrent mutations G111R and R173Q occurring at CpG motifs.
Porphyria, Acute Intermittent
Porphobilinogen deaminase and uroporphyrinogen III synthase: structure, molecular biology, and mechanism.
Porphyria, Acute Intermittent
Porphobilmogen deaminase gene mutations in Brazilian acute intermittent porphyria patients.
Porphyria, Acute Intermittent
Prevalence of acute intermittent porphyria in a Mexican psychiatric population.
Porphyria, Acute Intermittent
The dental management of five paediatric patients with a history of acute intermittent porphyria.
Porphyria, Acute Intermittent
Two different point G to A mutations in exon 10 of the porphobilinogen deaminase gene are responsible for acute intermittent porphyria.
Porphyria, Acute Intermittent
[Acute intermittent porphyria]
Porphyrias
Acute intermittent porphyria caused by a C----T mutation that produces a stop codon in the porphobilinogen deaminase gene.
Porphyrias
Acute intermittent porphyria in Sweden. Molecular, functional and clinical consequences of some new mutations found in the porphobilinogen deaminase gene.
Porphyrias
Acute intermittent porphyria in The Netherlands. Heterogeneity of the enzyme porphobilinogen deaminase.
Porphyrias
Acute intermittent porphyria with central pontine myelinolysis and cortical laminar necrosis.
Porphyrias
Acute intermittent porphyria: laboratory diagnosis by molecular methods.
Porphyrias
Acute intermittent porphyria: rapid molecular diagnosis.
Porphyrias
Circadian rhythms in acute intermittent porphyria--a pilot study.
Porphyrias
Direct assay of enzymes in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Porphobilinogen deaminase.
Porphyrias
Genetic heterogeneity of the porphobilinogen deaminase gene in Swedish families with acute intermittent porphyria.
Porphyrias
High frequency of mutations in exon 10 of the porphobilinogen deaminase gene in patients with a CRIM-positive subtype of acute intermittent porphyria.
Porphyrias
In inherited porphyrias, lead intoxication is a toxogenetic disorder.
Porphyrias
Influence of age and gender on the clinical expression of acute intermittent porphyria based on molecular study of porphobilinogen deaminase gene among Swiss patients.
Porphyrias
LT-11-056 liver transplantation for acute intermittent porphyria is complicated by a high rate of hepatic artery thrombosis.
Porphyrias
Molecular analysis of porphobilinogen (PBG) deaminase gene mutations in acute intermittent porphyria: first study in patients of Slavic origin.
Porphyrias
Molecular heterogeneity of acute intermittent porphyria: identification of four additional mutations resulting in the CRIM-negative subtype of the disease.
Porphyrias
Mutation hotspots in the human porphobilinogen deaminase gene: recurrent mutations G111R and R173Q occurring at CpG motifs.
Porphyrias
Porphobilinogen deaminase and uroporphyrinogen III synthase: structure, molecular biology, and mechanism.
Porphyrias
Porphobilmogen deaminase gene mutations in Brazilian acute intermittent porphyria patients.
Porphyrias
Prevalence of acute intermittent porphyria in a Mexican psychiatric population.
Porphyrias
The dental management of five paediatric patients with a history of acute intermittent porphyria.
Porphyrias
Two different point G to A mutations in exon 10 of the porphobilinogen deaminase gene are responsible for acute intermittent porphyria.
Porphyrias
[Acute intermittent porphyria]
Pre-Eclampsia
Elevated circulatingadenosine deaminase activity in women with preeclampsia: association with pro-inflammatory cytokine production and uric acid levels.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Primary Immunodeficiency Diseases
Importance of platelet-free preparations for evaluating lymphocyte nucleotide levels in inherited or acquired immunodeficiency syndromes.
Primary Immunodeficiency Diseases
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Prostatic Neoplasms
A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells.
Prostatic Neoplasms
Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells.
Prostatic Neoplasms
Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness.
Prostatic Neoplasms
Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors.
Pruritus
The N-Acylethanolamine Acid Amidase Inhibitor ARN077 Suppresses Inflammation and Pruritus in a Mouse Model of Allergic Dermatitis.
Psoriasis
[Metabolism of purine compounds in psoriasis]
pyrimidine-nucleoside phosphorylase deficiency
[Molecular pathology of immunological deficiency. Apropos of adenosine deaminase deficiency and nucleoside phosphorylase deficiency]
Pythiosis
E-ADA activity in lymphocytes of an experimental model of pythiosis treated with immunotherapy.
Renal Insufficiency
Glycoprotein metabolism in human renal disease: serum glycoproteins and glycoprotein: glycosyl transferase levels in chronic renal failure.
Renal Insufficiency, Chronic
Serum glycoprotein: glycosyl transferase activity in patients with renal disease.
Respiratory Insufficiency
[Carbamoyl ornithine transferase, arginase and cobalt-activated acylase in patients during asthma attacks or patients with respiratory failure]
Rhabdomyolysis
Primary Adenosine Monophosphate Deaminase Deficiency in a Hypotonic Infant.
Rhinitis, Allergic
Functional variants in the chromosome 4q21 locus contribute to allergic rhinitis risk by modulating the expression of N-acylethanolamine acid amidase.
Riboflavin Deficiency
[ENZYMATIC ACTIVITIES AND NUTRITIONAL STATES. II. ADENOSINE DEAMINASE. 2. ADENOSINE DEAMINASE OF THE SPLEEN AND KIDNEYS IN RIBOFLAVIN DEFICIENCY.]
Sarcoma
Abnormalities of cobalt-activated acylase from human sarcoma, carcinoma and the adjacent tissue.
Sarcoma
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Sarcoma
Tight binding inhibitors--VI. Interactions of deoxycoformycin and adenosine deaminase in intact human erythrocytes and sarcoma 180 cells.
Sarcoma 180
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Sarcoma 180
Tight binding inhibitors--VI. Interactions of deoxycoformycin and adenosine deaminase in intact human erythrocytes and sarcoma 180 cells.
Scleroderma, Systemic
[Antibodies to enzymes of purine metabolism as a factor of gastrointestinal tract lesions in systemic scleroderma]
Scrapie
Analyses of variants of the Ser/Thr dehydratase IlvA provide insight into 2-aminoacrylate metabolism in Salmonella enterica.
Scrapie
Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions.
Scrapie
Decreased coenzyme A levels in ridA mutant strains of Salmonella enterica result from inactivated serine hydroxymethyltransferase.
Scrapie
Evidence for a Negative Correlation between Human Reactive Enamine-Imine Intermediate Deaminase A (RIDA) Activity and Cell Proliferation Rate: Role of Lysine Succinylation of RIDA.
Scrapie
Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro.
Scrapie
PA5339, a RidA homolog, is required for full growth in Pseudomonas aeruginosa.
Scrapie
Putative Horizontally Acquired Genes, Highly Transcribed during Yersinia pestis Flea Infection, Are Induced by Hyperosmotic Stress and Function in Aromatic Amino Acid Metabolism.
Scrapie
Rid enhances the 6-hydroxypseudooxynicotine dehydrogenase reaction in nicotine degradation by Agrobacterium tumefaciens S33.
Scrapie
RidA Proteins Protect against Metabolic Damage by Reactive Intermediates.
Seizures
Cocaine: evidence for NMDA-, beta-carboline- and dopaminergic-mediated seizures in mice.
Sepsis
Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model.
Sepsis
Sepsis induced by cecal ligation and perforation (CLP) alters nucleotidase activities in platelets of rats.
Severe Combined Immunodeficiency
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
Severe Combined Immunodeficiency
Hyperbilirubinemia and Rapid Fatal Hepatic Failure in Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency (ADA-SCID).
Severe Combined Immunodeficiency
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
Severe Combined Immunodeficiency
Polymers for delivering peptides and proteins.
Severe Combined Immunodeficiency
Possible metabolic basis for the different immunodeficient states associated with genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylase.
Severe Combined Immunodeficiency
Standing on the Shoulders of Stem Cell Gene Therapists: History, Hyperbole, and Hope for the Future.
Severe Combined Immunodeficiency
Unusual retinopathy in a child with severe combined immune deficiency.
Severe Combined Immunodeficiency
[Adenosine deaminase in severe combined immunodeficiency syndrome].
Severe Combined Immunodeficiency
[Polyethylene glycol-adenosine deaminase: a new adenosine deaminase deficiency therapy. Value of deoxyadenosine triphosphate determination for therapeutic monitoring]
Severe Combined Immunodeficiency
[The human genome--chromosome 20]
Small Cell Lung Carcinoma
Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities.
Staphylococcal Infections
Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.
Stomach Neoplasms
Pyrimidine nucleotide synthesis is more extensive in poorly differentiated than in well-differentiated human gastric carcinoma.
Synucleinopathies
Deployment of Label-Free Quantitative Olfactory Proteomics to Detect Cerebrospinal Fluid Biomarker Candidates in Synucleinopathies.
Telangiectasis
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
Thiamine Deficiency
[ENZYME ACTIVITIES AND NUTRITIONAL STATES. II. ADENOSINE DEAMINASE. 1. ADENOSINE DEAMINASE IN THE SPLEEN AND KIDNEYS IN ASCORBIC ACID, BIOTIN AND THIAMINE DEFICIENCIES.]
Thrombocytopenia
Studies of cytomegalovirus infection in renal allograft recipients.
Thrombosis
Deglycosylation of fibrinogen accelerates polymerization and increases lateral aggregation of fibrin fibers.
Thyroid Neoplasms
Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors.
Trypanosomiasis
[Adenosine deaminase in experimental trypanosomiasis: future implications].
Tuberculosis
A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase.
Tuberculosis
Activity of n-propyl pyrazinoate against pyrazinamide-resistant Mycobacterium tuberculosis: investigations into mechanism of action of and mechanism of resistance to pyrazinamide.
Tuberculosis
Adenosine deaminase (ADA) isoenzyme analysis in pleural effusions: diagnostic role, and relevance to the origin of increased ADA in tuberculous pleurisy.
Tuberculosis
Auxiliary tools in tuberculosis. The hemolysis in pleural fluids underestimate the values of adenosine deaminase activity determined by the method of Giusti.
Tuberculosis
Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase.
Tuberculosis
Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting.
Tuberculosis
Cloning and sequencing of the gene which encodes the highly inducible acetamidase of Mycobacterium smegmatis.
Tuberculosis
Conditional sigma factor expression, using the inducible acetamidase promoter, reveals that the Mycobacterium tuberculosis sigF gene modulates expression of the 16-kilodalton alpha-crystallin homologue.
Tuberculosis
Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis.
Tuberculosis
Effect of Mycobacterium tuberculosis Rv3717 on cell division and cell adhesion.
Tuberculosis
Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides.
Tuberculosis
Importance of differentiating Mycobaterium bovis in tuberculous meningitis.
Tuberculosis
Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter.
Tuberculosis
Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors.
Tuberculosis
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Tuberculosis
Marine sponge derived natural products as inhibitors of mycothiol-S-conjugate amidase.
Tuberculosis
Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
Tuberculosis
Mutually exclusive genotypes for pyrazinamide and 5-chloropyrazinamide resistance reveal a potential resistance proofing strategy.
Tuberculosis
Mycobacterium tuberculosis prokaryotic ubiquitin-like protein (Pup) deconjugating enzyme Dop is an unusual aspartate amidase.
Tuberculosis
N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis.
Tuberculosis
New scoring system using tumor markers in diagnosing patients with moderate pericardial effusions.
Tuberculosis
Replacement of Mycobacterium smegmatis dnaA gene by Mycobacterium tuberculosis homolog results in temperature sensitivity.
Tuberculosis
Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis.
Tuberculosis
Structural and biochemical analyses of Mycobacterium tuberculosis N-acetylmuramyl L-alanine amidase Rv3717 point to a role in peptidoglycan fragment recycling.
Tuberculosis
Synthesis of a bromotyrosine-derived natural product inhibitor of mycothiol-S-conjugate amidase.
Tuberculosis
Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase.
Tuberculosis
The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization.
Tuberculosis
The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Tuberculosis
[Antimicrobial susceptibility testing for Mycobacterium tuberculosis by the bioluminescence assay of mycobacterial ATP using filamentous cell treatment]
Tuberculosis
[Cobalt-activated acylase activity in the serum of patients with tuberculosis treated with antitubercular agents]
Tuberculosis
[Tuberculous meningitis: tips for diagnosis and proposals for treatment].
Tuberculosis, Meningeal
Evaluation of CSF-adenosine deaminase activity in tubercular meningitis.
Tuberculosis, Pleural
Adenosine deaminase (ADA) isoenzyme analysis in pleural effusions: diagnostic role, and relevance to the origin of increased ADA in tuberculous pleurisy.
Tuberculosis, Pleural
Performance of the quantification of adenosine deaminase and determination of the lactate dehydrogenase/adenosine deaminase ratio for the diagnosis of pleural tuberculosis in children and adolescents.
Tuberculosis, Pleural
[A case of tuberculosis pleuritis with high serum soluble IL-2 receptor]
Tuberculosis, Pleural
[Informative value of adenosine deaminase and 2-deoxyadenosine deaminase in the diagnosis of tuberculous pleurisy]
Tuberculosis, Pleural
[Role of biomarkers in making the diagnosis of tuberculous pleurisy].
Tuberculosis, Pulmonary
Features purine metabolism in patients with pulmonary tuberculosis.
Tuberculosis, Pulmonary
[Cytokine production-adenosine deaminase activity relationship in pulmonary tuberculosis]
Tuberous Sclerosis
Serum and tissue proteins in tuberous sclerosis. I. Serum and red-cell polymorphic systems.
Urinary Bladder Neoplasms
Development of new inhibitors for N-acylethanolamine-hydrolyzing acid amidase as promising tool against bladder cancer.
Urinary Tract Infections
Rapid detection of urinary tract infection caused by Escherichia coli or Proteeae species.
Urinary Tract Infections
Rapid identification of micro-organisms from urinary tract infections by beta-glucuronidase, phenylalanine deaminase, cytochrome oxidase and indole tests on isolation media.
Urolithiasis
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Uterine Cervical Neoplasms
The role of Nuclear Factor-kappa B signaling in human cervical cancer.
Virus Diseases
Analysis of deoxycytidine (dC) deaminase activity in herpes simplex virus-infected or HSV TK-transformed cells: association with mycoplasma contamination but not with virus infection.
Virus Diseases
Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection.
Virus Diseases
Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection.
Virus Diseases
Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.
Vision, Low
Unusual retinopathy in a child with severe combined immune deficiency.
Warts
Mutation in the Drosophila melanogaster adenosine receptor gene selectively decreases the mosaic hyperplastic epithelial outgrowth rates in wts or dco heterozygous flies.
Whooping Cough
Bordetella pertussis waaA encodes a monofunctional 2-keto-3-deoxy-D-manno-octulosonic acid transferase that can complement an Escherichia coli waaA mutation.
Wiskott-Aldrich Syndrome
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side.
X-Linked Combined Immunodeficiency Diseases
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side.
Zenker Diverticulum
Morphology of the cricopharyngeal muscle in Zenker and control specimens.
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3.5.1.4 amidase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
