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Abruptio Placentae
Thrombin-enhanced matrix metalloproteinase-1 expression: a mechanism linking placental abruption with premature rupture of the membranes.
Acute Coronary Syndrome
Serum MMP-9 Diagnostics, Prognostics, and Activation in Acute Coronary Syndrome and Its Recurrence.
Acute Lung Injury
Matrix metalloproteinases and lung injury.
Adenocarcinoma
APE1 Upregulates MMP-14 via Redox-Sensitive ARF6-Mediated Recycling to Promote Cell Invasion of Esophageal Adenocarcinoma.
Adenocarcinoma
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Adenocarcinoma
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Adenocarcinoma
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Adenocarcinoma
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Adenocarcinoma
Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.
Adenocarcinoma
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Adenocarcinoma
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Adenocarcinoma
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Adenocarcinoma
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Adenocarcinoma
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Adenocarcinoma
Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
Adenocarcinoma
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Adenocarcinoma
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Adenocarcinoma
Interstitial collagenase gene expression in colonic neoplasia.
Adenocarcinoma
Localization of MT1-MMP, TIMP-1, TIMP-2, and TIMP-3 messenger RNA in normal, hyperplastic, and neoplastic endometrium. Enhanced expression by endometrial adenocarcinomas is associated with low differentiation.
Adenocarcinoma
Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.
Adenocarcinoma
Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors.
Adenocarcinoma
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Adenocarcinoma
MT1-MMP cooperates with KrasG12D to promote pancreatic fibrosis through increased TGF-{beta} signaling.
Adenocarcinoma
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
Adenocarcinoma
MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway.
Adenocarcinoma
No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China.
Adenocarcinoma
p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer.
Adenocarcinoma
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Adenocarcinoma
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Adenocarcinoma
The expression of MMP-14 and microRNA-410 in FFPE tissues of human endometrial adenocarcinoma.
Adenocarcinoma
[Changes of lymphatic vessel density in lung adenocarcinoma in situ, minimally invasive adenocarcinoma, and invasive adenocarcinoma and the regulatory factors].
Adenocarcinoma of Lung
Expression of extracellular matrix molecules in brain metastasis.
Adenocarcinoma of Lung
The role of matrix metalloproteinase in the intimal sarcoma-like cells derived from endarterectomized tissues from a chronic thromboembolic pulmonary hypertension patient.
Adenocarcinoma of Lung
[MiR-373-3p Promotes Invasion and Metastasis of Lung Adenocarcinoma Cells].
Adenocarcinoma, Follicular
Matrix metalloproteinase (MMP) expression by differentiated thyroid carcinoma of children and adolescents.
Adenoma
Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.
Adenoma
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Adenoma
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Adenoma
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Adenoma
Interstitial collagenase gene expression in colonic neoplasia.
Adenoma
Matrix metalloproteases expression in different histological types of colorectal polyps.
Adenoma
Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.
Adenomatous Polyposis Coli
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Adenomatous Polyposis Coli
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/?-catenin signalling pathway.
Adenomatous Polyps
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Agenesis of Corpus Callosum
MT1-MMP deficiency leads to defective ependymal cell maturation, impaired ciliogenesis, and hydrocephalus.
Aggressive Periodontitis
Collagenase activity in gingival crevicular fluid of patients with juvenile periodontitis.
Aggressive Periodontitis
Tetracycline inhibition identifies the cellular origin of interstitial collagenases in human periodontal diseases in vivo.
Aggressive Periodontitis
Tetracycline inhibition identifies the cellular sources of collagenase in gingival crevicular fluid in different forms of periodontal diseases.
Alveolar Bone Loss
Matrix Metalloproteinases, Tissue Inhibitor of Matrix Metalloproteinase-1, and Laminin-5 ?2 Chain Immunolocalization in Gingival Tissue of Endotoxin-Induced Periodontitis in Rats: Effects of Low-Dose Doxycycline and Alendronate.
Alveolar Bone Loss
Matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase-1, and laminin-5 gamma2 chain immunolocalization in gingival tissue of endotoxin-induced periodontitis in rats: effects of low-dose doxycycline and alendronate.
Alzheimer Disease
Abnormal Expression and Distribution of MMP2 at Initial Stages of Alzheimer's Disease-Related Pathology.
Alzheimer Disease
Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease.
Alzheimer Disease
Differential spatio-temporal regulation of MMPs in the 5xFAD mouse model of Alzheimer's disease: evidence for a pro-amyloidogenic role of MT1-MMP.
Alzheimer Disease
Emerging Alternative Proteinases in APP Metabolism and Alzheimer's Disease Pathogenesis: A Focus on MT1-MMP and MT5-MMP.
Alzheimer Disease
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Ameloblastoma
Expression and role of metalloproteinase-2 and endogenous tissue regulator in ameloblastoma.
Ameloblastoma
Immunohistochemical detection of MT1-MMP, RECK, and EMMPRIN in ameloblastic tumors.
Amyloidosis
Chaperone Nanobodies Protect Gelsolin Against MT1-MMP Degradation and Alleviate Amyloid Burden in the Gelsolin Amyloidosis Mouse Model.
Amyloidosis
Overexpression of serum amyloid A-activating factor 1 inhibits cell proliferation by the induction of cyclin-dependent protein kinase inhibitor p21WAF-1/Cip-1/Sdi-1 expression.
Amyotrophic Lateral Sclerosis
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Aneurysm
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Aneurysm
Adverse drug reaction prediction using scores produced by large-scale drug-protein target docking on high-performance computing machines.
Aneurysm
Early Increased MT1-MMP Expression and Late MMP-2 and MMP-9 Activity during Angiotensin II Induced Aneurysm Formation.
Aneurysm
Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta.
Aneurysm
Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms.
Aneurysm
Vascular extracellular matrix remodeling in cerebral aneurysms.
Angiofibroma
Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
Aortic Aneurysm
Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions.
Aortic Aneurysm
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Aortic Aneurysm
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Aortic Aneurysm, Abdominal
Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall.
Aortic Aneurysm, Abdominal
Demonstration of interstitial collagenase in abdominal aortic aneurysm disease.
Aortic Aneurysm, Abdominal
Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo.
Aortic Valve Stenosis
A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor ?-1 to Soluble Endoglin Ratio.
Arthritis
Assignments, secondary structure and dynamics of the inhibitor-free catalytic fragment of human fibroblast collagenase.
Arthritis
Design and synthesis of sulfur based inhibitors of matrix metalloproteinase-1.
Arthritis
Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis.
Arthritis
Influence of Matrix metalloproteinase 1 and 3 genetic variations on susceptibility and severity of juvenile idiopathic arthritis.
Arthritis
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Arthritis
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism.
Arthritis
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover.
Arthritis
Mutation of Membrane Type-1 Metalloproteinase, MT1-MMP, Causes the Multicentric Osteolysis and Arthritis Disease Winchester Syndrome.
Arthritis
New biochemical insight of conserved water molecules at catalytic and structural Zn(2+) ions in human matrix metalloproteinase-I: a study by MD-simulation.
Arthritis
Overexpression of serum amyloid A-activating factor 1 inhibits cell proliferation by the induction of cyclin-dependent protein kinase inhibitor p21WAF-1/Cip-1/Sdi-1 expression.
Arthritis
Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade.
Arthritis
The road forward: The scientific basis for tetracycline treatment of arthritic disorders.
Arthritis, Experimental
Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.
Arthritis, Experimental
Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031.
Arthritis, Juvenile
Influence of Matrix metalloproteinase 1 and 3 genetic variations on susceptibility and severity of juvenile idiopathic arthritis.
Arthritis, Reactive
Reduction of matrix metalloproteinase 8-neutrophil collagenase levels during long-term doxycycline treatment of reactive arthritis.
Arthritis, Rheumatoid
A high throughput fluorogenic substrate for interstitial collagenase (MMP-1) and gelatinase (MMP-9).
Arthritis, Rheumatoid
Analysis for the major contributor of collagenase to the primary cleavage of type II collagens in cartilage degradation.
Arthritis, Rheumatoid
Collagenase (MMP-1) and TIMP-1 in destructive corneal disease associated with rheumatoid arthritis.
Arthritis, Rheumatoid
Collagenase-1 (MMP-1) and HLA-DRB1 gene polymorphisms in rheumatoid arthritis: a prospective longitudinal study.
Arthritis, Rheumatoid
Determination of interstitial collagenase (MMP-1) in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis.
Arthritis, Rheumatoid
Examination of recombinant truncated mature human fibroblast collagenase by mass spectrometry: identification of differences with the published sequence and determination of stable isotope incorporation.
Arthritis, Rheumatoid
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium.
Arthritis, Rheumatoid
Expression of membrane-type 1 matrix metalloproteinase in rheumatoid synovial cells.
Arthritis, Rheumatoid
Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium.
Arthritis, Rheumatoid
Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts.
Arthritis, Rheumatoid
Follistatin-like protein 1 induction of matrix metalloproteinase 1, 3 and 13 gene expression in rheumatoid arthritis synoviocytes requires MAPK, JAK/STAT3 and NF-?B pathways.
Arthritis, Rheumatoid
From supernatants to cytokines: a personal view on the early history of IL-1, IL-1Ra, TNF and its inhibitor in rheumatology.
Arthritis, Rheumatoid
Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
Arthritis, Rheumatoid
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Arthritis, Rheumatoid
Membrane-type I matrix metalloproteinase-dependent regulation of rheumatoid arthritis synoviocyte function.
Arthritis, Rheumatoid
MT1-MMP: a potent modifier of pericellular microenvironment.
Arthritis, Rheumatoid
Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts.
Arthritis, Rheumatoid
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
Arthritis, Rheumatoid
Reduction of serum matrix metalloproteinase 1 and matrix metalloproteinase 3 in rheumatoid arthritis patients following anti-tumour necrosis factor-alpha (cA2) therapy.
Arthritis, Rheumatoid
Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.
Arthritis, Rheumatoid
Regulation of human synovial fibroblast collagenase messenger RNA by interleukin-1.
Arthritis, Rheumatoid
Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts.
Arthritis, Rheumatoid
Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts.
Arthritis, Rheumatoid
Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts.
Arthritis, Rheumatoid
Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts.
Arthritis, Rheumatoid
Stimulation of collagenase 3 expression in synovial fibroblasts of patients with rheumatoid arthritis by contact with a three-dimensional collagen matrix or with normal cartilage when coimplanted in NOD/SCID mice.
Arthritis, Rheumatoid
The involvement of matrix metalloproteinases and inflammation in lumbar disc herniation.
Arthritis, Rheumatoid
The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism.
Arthritis, Rheumatoid
Variation of Matrix Metalloproteinase 1 and 3 Haplotypes and Their Serum Levels in Patients with Rheumatoid Arthritis and Osteoarthritis.
Asthma
Broncho-alveolar macrophages express chemokines associated with leukocyte migration in a mouse model of asthma.
Asthma
Long-term pathologic consequences of acute irritant-induced asthma.
Asthma
[The analysis of amount of matrix metalloproteinase 1 precursor, metalloproteinase 1 tissue inhibitor and cystatin C in the bronchoalveolar secretion of patients with nonspecific lung diseases].
Astrocytoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Astrocytoma
Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas.
Astrocytoma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Atherosclerosis
Acceleration of matrix metalloproteinase-1 production and activation of platelet-derived growth factor receptor beta in human coronary smooth muscle cells by oxidized LDL and 4-hydroxynonenal.
Atherosclerosis
Basic FGF regulates interstitial collagenase gene expression in human smooth muscle cells.
Atherosclerosis
Cleavage and functional loss of human apolipoprotein E by digestion of matrix metalloproteinase-14.
Atherosclerosis
Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells.
Atherosclerosis
Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.
Atherosclerosis
Imaging with radiolabelled anti-membrane type 1 matrix metalloproteinase (MT1-MMP) antibody: potentials for characterizing atherosclerotic plaques.
Atherosclerosis
Induction of the MMP-14 gene in macrophages of the atherosclerotic plaque: role of SAF-1 in the induction process.
Atherosclerosis
MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-? and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.
Atherosclerosis
Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators.
Atherosclerosis
Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis.
Atherosclerosis
Membrane-Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions.
Atherosclerosis
Membrane-type I matrix metalloproteinase (MT1-MMP), lipid metabolism and therapeutic implications.
Atherosclerosis
Overexpression of serum amyloid A-activating factor 1 inhibits cell proliferation by the induction of cyclin-dependent protein kinase inhibitor p21WAF-1/Cip-1/Sdi-1 expression.
Atherosclerosis
Specific matrix metalloproteinases play different roles in intraplaque angiogenesis and plaque instability in rabbits.
Atrioventricular Block
Matrix metalloproteinase 1 1?G/2?G gene polymorphism is associated with acquired atrioventricular block via linking a higher serum protein level.
Bacterial Infections
Ras-oncogenic Drosophila hindgut but not midgut cells use an inflammation-like program to disseminate to distant sites.
Bicuspid Aortic Valve Disease
Low transcriptional activity haplotype of matrix metalloproteinase 1 is less frequent in bicuspid aortic valve patients.
Blister
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Blister
Urokinase plasminogen activator is expressed by basal keratinocytes before interstitial collagenase, stromelysin-1, and laminin-5 in experimentally induced dermatitis herpetiformis lesions.
Bone Diseases, Metabolic
Delayed tooth eruption in membrane type-1 matrix metalloproteinase deficient mice.
Bone Diseases, Metabolic
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism.
Bone Diseases, Metabolic
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover.
Bone Resorption
1alpha,25-dihydroxyvitamin D3 regulates the expression of membrane-type matrix metalloproteinase-1 in normal human osteoblast-like cells.
Bone Resorption
Differential expression pattern of membrane-type matrix metalloproteinases in rheumatoid arthritis.
Bone Resorption
Effects of 17beta-estradiol on the expression of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in human osteoblastic MG-63 cell cultures.
Bone Resorption
Immunohistochemical localization of membrane type 1-matrix metalloproteinase (MT1-MMP) in osteoclasts in vivo.
Bone Resorption
Initiation of osteoclast bone resorption by interstitial collagenase.
Bone Resorption
Interstitial collagenase activity stimulates the formation of actin rings and ruffled membranes in mouse marrow osteoclasts.
Bone Resorption
Localisation of mRNA for collagenase in osteocytic, bone surface and chondrocytic cells but not osteoclasts.
Bone Resorption
Membrane Localization of Membrane Type 1 Matrix Metalloproteinase by CD44 Regulates the Activation of Pro-Matrix Metalloproteinase 9 in Osteoclasts.
Bone Resorption
Membrane-type-1 matrix metalloproteinase is abundantly expressed in fibroblasts and osteoclasts at the bone-implant interface of aseptically loosened joint arthroplasties in situ.
Bone Resorption
Minocycline impairment of both osteoid tissue removal and osteoclastic resorption in a synchronized model of remodeling in the rat.
Bone Resorption
Nitric oxide promotes infectious bone resorption by enhancing cytokine-stimulated interstitial collagenase synthesis in osteoblasts.
Bone Resorption
Parathyroid hormone inhibits the expression of membrane-type matrix metalloproteinase-1 (MT1-MMP) in osteoblast-like MG-63 cells.
Bone Resorption
The role of collagenase in bone resorption. An overview.
Bone Resorption
Transcriptional regulation of the collagenase gene by basic fibroblast growth factor in osteoblastic MC3T3-E1 cells.
Bone Resorption
[The effects of 1alpha,25-dihydroxyvitamin D3 in regulation matrix metalloproteinase and tissue metalloproteinase inhibitors in human osteoblasts.]
Bowen's Disease
Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma.
Brain Injuries, Traumatic
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Brain Ischemia
Effects of treadmill exercise on cerebral angiogenesis and MT1-MMP expression after cerebral ischemia in rats.
Brain Neoplasms
Cell-based evidence for aminopeptidase N/CD13 inhibitor actinonin targeting of MT1-MMP-mediated proMMP-2 activation.
Brain Neoplasms
Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells.
Brain Neoplasms
Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.
Brain Neoplasms
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas.
Brain Neoplasms
Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells.
Brain Neoplasms
Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling.
Brain Neoplasms
Silencing of the MT1-MMP/ G6PT axis suppresses calcium mobilization by sphingosine-1-phosphate in glioblastoma cells.
Brain Neoplasms
Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype.
Breast Neoplasms
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Breast Neoplasms
Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells.
Breast Neoplasms
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth.
Breast Neoplasms
Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells.
Breast Neoplasms
An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase.
Breast Neoplasms
An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer.
Breast Neoplasms
Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase.
Breast Neoplasms
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.
Breast Neoplasms
Assessment of the MT1-MMP expression level of different cell lines by the naked eye.
Breast Neoplasms
Association of BCSC-1 and MMP-14 with human breast cancer.
Breast Neoplasms
ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion.
Breast Neoplasms
Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells.
Breast Neoplasms
Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.
Breast Neoplasms
Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis.
Breast Neoplasms
Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1 beta (IL-1 beta) in human fibroblasts and BC-8701 breast cancer cells.
Breast Neoplasms
Cellular membrane type-1 matrix metalloproteinase (MT1-MMP) cleaves C3b, an essential component of the complement system.
Breast Neoplasms
Chemical Tools for Selective Activity Profiling of Endogenously Expressed MMP-14 in Multicellular Models.
Breast Neoplasms
Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase.
Breast Neoplasms
CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer.
Breast Neoplasms
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Breast Neoplasms
Clinical significance of MT1-MMP mRNA expression in breast cancer.
Breast Neoplasms
Coagulation factor VIIa-mediated protease-activated receptor 2 activation leads to ?-catenin accumulation via the AKT/GSK3? pathway and contributes to breast cancer progression.
Breast Neoplasms
Control of MT1-MMP transport by atypical PKC during breast-cancer progression.
Breast Neoplasms
Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function.
Breast Neoplasms
Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.
Breast Neoplasms
DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells.
Breast Neoplasms
Development of a Radiolabeled Peptide-Based Probe Targeting MT1-MMP for Breast Cancer Detection.
Breast Neoplasms
Development of a radiolabeled probe for detecting membrane type-1 matrix metalloproteinase on malignant tumors.
Breast Neoplasms
Development of an optimized activatable MMP-14 targeted SPECT imaging probe.
Breast Neoplasms
Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy.
Breast Neoplasms
Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts.
Breast Neoplasms
DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes.
Breast Neoplasms
Effect of the different phosphorylated Smad2 protein localizations on the invasive breast carcinoma phenotype.
Breast Neoplasms
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Breast Neoplasms
Enhanced membrane-type 1 matrix metalloproteinase expression by hyaluronan oligosaccharides in breast cancer cells facilitates CD44 cleavage and tumor cell migration.
Breast Neoplasms
EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.
Breast Neoplasms
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Breast Neoplasms
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Breast Neoplasms
Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells.
Breast Neoplasms
Expression of extracellular matrix molecules in brain metastasis.
Breast Neoplasms
Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells.
Breast Neoplasms
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Breast Neoplasms
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Breast Neoplasms
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas.
Breast Neoplasms
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Breast Neoplasms
Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.
Breast Neoplasms
Gelatin zymography and substrate cleavage assays of matrix metalloproteinase-2 in breast carcinoma cells overexpressing membrane type-1 matrix metalloproteinase.
Breast Neoplasms
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Breast Neoplasms
Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid.
Breast Neoplasms
Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation.
Breast Neoplasms
Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis.
Breast Neoplasms
Immunolocalization of matrix metalloproteinases and their inhibitors in clinical specimens of bone metastasis from breast carcinoma.
Breast Neoplasms
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Breast Neoplasms
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Breast Neoplasms
In vitro and in vivo MMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts.
Breast Neoplasms
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Breast Neoplasms
Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels.
Breast Neoplasms
Integrin fibronectin receptors in matrix metalloproteinase-1-dependent invasion by breast cancer and mammary epithelial cells.
Breast Neoplasms
Interleukin-1 beta induces interstitial collagenase gene expression and protein secretion in renal mesangial cells.
Breast Neoplasms
Intradomain cleavage of the inhibitory prodomain is essential to the pro-tumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo.
Breast Neoplasms
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.
Breast Neoplasms
LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.
Breast Neoplasms
Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells.
Breast Neoplasms
Mapping proteolytic cancer cell-extracellular matrix interfaces.
Breast Neoplasms
Matrix metalloproteinase 1 and circulating tumor cells in early breast cancer.
Breast Neoplasms
Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material.
Breast Neoplasms
mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization.
Breast Neoplasms
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules.
Breast Neoplasms
Membrane type 1 matrix metalloproteinase-mediated stromal syndecan-1 shedding stimulates breast carcinoma cell proliferation.
Breast Neoplasms
Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses.
Breast Neoplasms
Membrane type-1 matrix metalloproteinase (MT1-MMP) processing of pro-alphav integrin regulates cross-talk between alphavbeta3 and alpha2beta1 integrins in breast carcinoma cells.
Breast Neoplasms
Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins.
Breast Neoplasms
Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells.
Breast Neoplasms
Membrane-type 1 matrix metalloproteinase regulates fibronectin assembly to promote cell motility.
Breast Neoplasms
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
Breast Neoplasms
Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin ?5?1 and tumour growth.
Breast Neoplasms
MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.
Breast Neoplasms
MMP-14 Triggered Fluorescence Contrast Agent.
Breast Neoplasms
MMP1 expression is activated by Slug and enhances multi-drug resistance (MDR) in breast cancer.
Breast Neoplasms
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Breast Neoplasms
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
Breast Neoplasms
MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis.
Breast Neoplasms
MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.
Breast Neoplasms
MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis.
Breast Neoplasms
MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src.
Breast Neoplasms
MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart.
Breast Neoplasms
MT1-MMP: Endosomal delivery drives breast cancer metastasis.
Breast Neoplasms
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion.
Breast Neoplasms
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
Breast Neoplasms
Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP.
Breast Neoplasms
Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14.
Breast Neoplasms
New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
Breast Neoplasms
Non-destructive and selective imaging of the functionally active, pro-invasive membrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells.
Breast Neoplasms
p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer.
Breast Neoplasms
Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP.
Breast Neoplasms
Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding.
Breast Neoplasms
Plasma matrix metalloproteinase 1, 3, and 7 levels and breast cancer risk in the Nurses' Health study.
Breast Neoplasms
PLD and PA Take MT1-MMP for a Metastatic Ride.
Breast Neoplasms
Prinomastat, a hydroxamate inhibitor of matrix metalloproteinases, has a complex effect on migration of breast carcinoma cells.
Breast Neoplasms
Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.
Breast Neoplasms
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion.
Breast Neoplasms
Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells.
Breast Neoplasms
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
Breast Neoplasms
Radiation-enhancement of MDA-MB-231 breast cancer cell invasion prevented by a cyclooxygenase-2 inhibitor.
Breast Neoplasms
Regulation of invadopodia formation and activity by CD147.
Breast Neoplasms
Regulation of MT1-MMP Activity through Its Association with ERMs.
Breast Neoplasms
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Breast Neoplasms
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.
Breast Neoplasms
Shedding of discoidin domain receptor (DDR) 1 by membrane type (MT)-matrix metalloproteinases (MMPs).
Breast Neoplasms
Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line.
Breast Neoplasms
Significance of membrane type 1 matrix metalloproteinase expression in breast cancer.
Breast Neoplasms
SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis.
Breast Neoplasms
Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells.
Breast Neoplasms
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines.
Breast Neoplasms
Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines.
Breast Neoplasms
Studies on Multifunctional Effect of All-Trans Retinoic Acid (ATRA) on Matrix Metalloproteinase-2 (MMP-2) and Its Regulatory Molecules in Human Breast Cancer Cells (MCF-7).
Breast Neoplasms
Synergistic effect of collagenase-1 (MMP1), stromelysin-1 (MMP3) and gelatinase-B (MMP9) gene polymorphisms in breast cancer.
Breast Neoplasms
Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.
Breast Neoplasms
The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells.
Breast Neoplasms
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
Breast Neoplasms
The membrane tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo- and radiotherapy responses of breast cancer.
Breast Neoplasms
The multiple roles of Id-1 in cancer progression.
Breast Neoplasms
The overexpression membrane type 1 matrix metalloproteinase is associated with the progression and prognosis in breast cancer.
Breast Neoplasms
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
Breast Neoplasms
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
Breast Neoplasms
TNF-? promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts.
Breast Neoplasms
TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.
Breast Neoplasms
Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter.
Breast Neoplasms
Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases.
Breast Neoplasms
Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: a major induction of stromal MMP-13.
Breast Neoplasms
Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
Breast Neoplasms
YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis.
Breast Neoplasms
[Effects of MT1-MMP on the in vitro invasiveness of breast cancer cells]
Breast Neoplasms
[Expression pattern of membrane type-1 matrix metalloproteinase in primary breast carcinomas].
Breast Neoplasms
[MT1-MMP up-regulates VEGF expression in human breast carcinoma MCF-7 cells and induces tumor angiogenesis]
Breast Neoplasms
[Significance of membrane type-1 matrix metalloproteinase expression in breast cancer]
Bronchiectasis
[Complex search for antiprotease-protease enzyme gene polymorphisms in patients with chronic obstructive pulmonary diseases]
Bronchitis
[Complex search for antiprotease-protease enzyme gene polymorphisms in patients with chronic obstructive pulmonary diseases]
Carcinogenesis
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
Carcinogenesis
Collagenase induction promotes mouse tumorigenesis by two independent pathways.
Carcinogenesis
Contribution of matrix metalloproteinases-1 genotypes to gastric cancer susceptibility in Taiwan.
Carcinogenesis
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.
Carcinogenesis
Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival.
Carcinogenesis
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Carcinogenesis
Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2.
Carcinogenesis
Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
Carcinogenesis
Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.
Carcinogenesis
Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.
Carcinogenesis
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.
Carcinogenesis
Lumican, pro-tumorigenic or anti-tumorigenic: A conundrum.
Carcinogenesis
Matrix metalloproteinase 1 gene polymorphism as a prognostic predictor of invasive cervical cancer.
Carcinogenesis
Matrix metalloproteinase 1 promotes tumorigenesis and inhibits the sensitivity to 5-fluorouracil of nasopharyngeal carcinoma.
Carcinogenesis
Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer.
Carcinogenesis
miRNA-584-3p inhibits gastric cancer progression by repressing Yin Yang 1- facilitated MMP-14 expression.
Carcinogenesis
Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.
Carcinogenesis
Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma.
Carcinogenesis
Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice.
Carcinogenesis
The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells.
Carcinogenesis
The polymorphism MMP1 -1607 (1G>2G) is associated with a significantly increased risk of cancers from a meta-analysis.
Carcinogenesis
The role of matrix metalloproteinase in the intimal sarcoma-like cells derived from endarterectomized tissues from a chronic thromboembolic pulmonary hypertension patient.
Carcinogenesis
TIMP-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.
Carcinogenesis
TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway.
Carcinogenesis
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Carcinogenesis
[Tissue collagenase MMP-14 and endogenous regulators of its activity in the corpus uteri in squamous cell carcinoma of the cervix].
Carcinoma
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2.
Carcinoma
Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2.
Carcinoma
AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner.
Carcinoma
An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy.
Carcinoma
Analysis of MT1-MMP and MMP2 expression in human gastric cancers.
Carcinoma
Anti-invasive effect of MMI-166, a new selective matrix metalloproteinase inhibitor, in cervical carcinoma cell lines.
Carcinoma
Augmented membrane type 1 matrix metalloproteinase (MT1-MMP):MMP-2 messenger RNA ratio in gastric carcinomas with poor prognosis.
Carcinoma
Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
Carcinoma
Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell Invasion.
Carcinoma
Changes in the expression of matrix proteases and of the transcription factor c-Ets-1 during progression of precancerous bronchial lesions.
Carcinoma
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Carcinoma
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Carcinoma
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Carcinoma
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.
Carcinoma
Construction of antisense MT1-MMP vector and its inhibitory effects on invasion of human ovarian cancer cells.
Carcinoma
Contribution of the PI3K/MMPs/Ln-5?2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Carcinoma
Coordinated expression of integrin subunits, matrix metalloproteinases (MMP), angiogenic genes and Ets transcription factors in advanced-stage ovarian carcinoma: a possible activation pathway?
Carcinoma
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Carcinoma
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Carcinoma
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Carcinoma
Differential localization of MT1-MMP in human prostate cancer tissue: Role of IGF-1R in MT1-MMP expression.
Carcinoma
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Carcinoma
Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes.
Carcinoma
Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.
Carcinoma
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Carcinoma
Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells.
Carcinoma
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Carcinoma
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Carcinoma
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Carcinoma
Enhanced collagenase production by fibroblasts derived from human basal cell carcinomas.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Carcinoma
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Carcinoma
Epidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagen.
Carcinoma
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Carcinoma
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Carcinoma
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas.
Carcinoma
Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma.
Carcinoma
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Carcinoma
Expression of collagenase-1 (MMP-1), collagenase-3 (MMP-13) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in laryngeal squamous cell carcinomas.
Carcinoma
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Carcinoma
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Carcinoma
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Carcinoma
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Carcinoma
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Carcinoma
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Carcinoma
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Carcinoma
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Carcinoma
Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion.
Carcinoma
Expression of membrane type 1-matrix metalloproteinase in laryngeal carcinoma.
Carcinoma
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.
Carcinoma
Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas.
Carcinoma
Expression of messenger RNAs for membrane-type 1, 2, and 3 matrix metalloproteinases in human renal cell carcinomas.
Carcinoma
Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas.
Carcinoma
Expression of metastasis-associated mts1 gene is co-induced with membrane type-1 matrix metalloproteinase (MT1-MMP) during oncogenic transformation and tubular formation of Madin Darby canine kidney (MDCK) epithelial cells.
Carcinoma
Expression of MMP-14 and prognosis in digestive system carcinoma: a meta-analysis and databases validation.
Carcinoma
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Carcinoma
Expression of MMP-7 and MT1-MMP in oral squamous cell carcinoma as predictive indicator for tumor invasion and prognosis.
Carcinoma
Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
Carcinoma
Fibroblast growth factor-1 transcriptionally induces membrane type-1 matrix metalloproteinase expression in prostate carcinoma cell line.
Carcinoma
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Carcinoma
Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype.
Carcinoma
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
Carcinoma
Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence.
Carcinoma
HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis.
Carcinoma
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Carcinoma
Identification of a metalloproteinase co-purifying with rat tumour collagenase and the characteristics of fragments of both enzymes.
Carcinoma
Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
Carcinoma
Identification of novel target proteins in sebaceous gland carcinoma.
Carcinoma
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Carcinoma
Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma.
Carcinoma
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Carcinoma
Immunolocalization of collagenase in neoplastic epithelial cells.
Carcinoma
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Carcinoma
Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness.
Carcinoma
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Carcinoma
Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.
Carcinoma
Increased immunoreactivity of MT1-MMP and beta-catenin in high risk basal cell carcinoma.
Carcinoma
Interaction of MT1-MMP and laminin-5gamma2 chain correlates with metastasis and invasiveness in human esophageal squamous cell carcinoma.
Carcinoma
Interstitial collagenase (matrix metalloproteinase 1) associated with the plasma membrane of both neoplastic and nonneoplastic cells.
Carcinoma
Interstitial collagenase from rat mammary carcinoma cells: interaction with substrates and inhibitors.
Carcinoma
Interstitial collagenase gene expression in oral squamous cell carcinoma.
Carcinoma
Interstitial collagenase MMP-1 and EMMPRIN in cell lines and in clinical specimens of cervical squamous cell carcinoma.
Carcinoma
Intratumoral concentrations of tissue inhibitor of matrix metalloproteinase 1 in patients with gastric carcinoma a new biomartker for invasion and its impact on survival.
Carcinoma
Invasion of connective tissue by human carcinoma cell lines: requirement for urokinase, urokinase receptor, and interstitial collagenase.
Carcinoma
Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression.
Carcinoma
Mammary carcinoma with osteoclast-like giant cells: a case report.
Carcinoma
Matrix metalloproteinase 1, 3, and 9 polymorphisms and esophageal squamous cell carcinoma risk.
Carcinoma
Matrix metalloproteinase 1: a better biomarker for squamous cell carcinoma by multiple microarray analyses.
Carcinoma
Matrix metalloproteinase-14 (MMP-14) downregulation inhibits esophageal squamous cell carcinoma cell migration, invasion, and proliferation.
Carcinoma
Matrix metalloproteinase-14 expression and its prognostic value in cervical carcinoma.
Carcinoma
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Carcinoma
Matrix-metalloproteinases in bronchopulmonary carcinomas.
Carcinoma
Membrane type 1 matrix metalloproteinase-mediated stromal syndecan-1 shedding stimulates breast carcinoma cell proliferation.
Carcinoma
Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor.
Carcinoma
Membrane type I-matrix metalloproteinase-mediated degradation of type I collagen by oral squamous cell carcinoma cells.
Carcinoma
Membrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer.
Carcinoma
Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration.
Carcinoma
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Carcinoma
Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
Carcinoma
MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines.
Carcinoma
MMP-14 can serve as a prognostic marker in patients with supraglottic cancer.
Carcinoma
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Carcinoma
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma
MT1-MMP Activation of TGF-? Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer.
Carcinoma
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
Carcinoma
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Carcinoma
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
Carcinoma
MT1-MMP regulates urothelial cell invasion via transcriptional regulation of Dickkopf-3.
Carcinoma
MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins.
Carcinoma
MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma.
Carcinoma
Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts.
Carcinoma
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
Carcinoma
No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China.
Carcinoma
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
Carcinoma
Plasma matrix metalloproteinase 1 improves the detection and survival prediction of esophageal squamous cell carcinoma.
Carcinoma
Podoplanin promotes the invasion of oral squamous cell carcinoma in coordination with MT1-MMP and Rho GTPases.
Carcinoma
Polarized MT1-MMP-CD44 interaction and CD44 cleavage during cell retraction reveal an essential role for MT1-MMP in CD44-mediated invasion.
Carcinoma
Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
Carcinoma
Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
Carcinoma
Prognostic significance of matrix metalloproteinases type I expression and tumor front parameters in the presence of lymph node micrometastases in carcinoma of the larynx.
Carcinoma
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Carcinoma
Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells.
Carcinoma
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma
Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells.
Carcinoma
RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology.
Carcinoma
Relation between laminin-5 gamma 2 chain and cell surface metalloproteinase MT1-MMP in clear cell carcinoma of the ovary.
Carcinoma
SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2.
Carcinoma
Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.
Carcinoma
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Carcinoma
Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer.
Carcinoma
Stimulation of skin fibroblast collagenase production by a cytokine derived from basal cell carcinomas.
Carcinoma
Stromelysin-3 induction and interstitial collagenase repression by retinoic acid. Therapeutical implication of receptor-selective retinoids dissociating transactivation and AP-1-mediated transrepression.
Carcinoma
The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.
Carcinoma
The identification, purification and characterisation of an inhibitor of collagenase (20K) produced by neoplastic epithelial cells.
Carcinoma
The Precise Diagnosis of Cancer Invasion/Metastasis via 2D Laser Ablation Mass Mapping of Metalloproteinase in Primary Cancer Tissue.
Carcinoma
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
Carcinoma
Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves alphav integrins and the participation of MMP2.
Carcinoma
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Carcinoma
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Carcinoma
Upregulated expression and activation of membrane?associated proteases in esophageal squamous cell carcinoma.
Carcinoma
Visual and automated assessment of matrix metalloproteinase-14 tissue expression for the evaluation of ovarian cancer prognosis.
Carcinoma
[Correlation of membrane type I matrix metalloproteinase (MT1-MMP) expression with clinicomorphological features of tumor front in squamous cell carcinoma of the larynx]
Carcinoma
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
Carcinoma
[Expression levels of MMP-14, ING4 and HIF-1? in 60 patients with oral squamous cell carcinoma and their clinical significance].
Carcinoma
[Expression of matrix metalloproteinase 1 in tissue of colon carcinoma and its clinical prognostic significance].
Carcinoma
[Expression of MMP1 mRNA in oral squamous cell carcinoma and paired normal tissues]
Carcinoma
[Expression of MT1-MMP and RECK protein in human gastric carcinoma].
Carcinoma
[Expression pattern of membrane type-1 matrix metalloproteinase in primary breast carcinomas].
Carcinoma
[Inhibitory effect of MT1-MMP antisense nucleotide on invasion of human highly metastatic ovarian cancer cell line SW626.]
Carcinoma
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Carcinoma
[Morphological tumor front grading and matrix metalloproteinases type I expression as a prognostic parameter of the presence of lymph node micrometastases in laryngeal carcinoma]
Carcinoma
[Significance of membrane type-1 matrix metalloproteinase expression in breast cancer]
Carcinoma
[Tissue collagenase MMP-14 and endogenous regulators of its activity in the corpus uteri in squamous cell carcinoma of the cervix].
Carcinoma in Situ
Changes in the expression of matrix proteases and of the transcription factor c-Ets-1 during progression of precancerous bronchial lesions.
Carcinoma, Basal Cell
Enhanced collagenase production by fibroblasts derived from human basal cell carcinomas.
Carcinoma, Basal Cell
Increased immunoreactivity of MT1-MMP and beta-catenin in high risk basal cell carcinoma.
Carcinoma, Basal Cell
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma, Basal Cell
Stimulation of skin fibroblast collagenase production by a cytokine derived from basal cell carcinomas.
Carcinoma, Ductal
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Carcinoma, Ductal
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Carcinoma, Endometrioid
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma, Hepatocellular
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Assessing matrix metalloproteinase expression and activity in hepatocellular carcinomas.
Carcinoma, Hepatocellular
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Carcinoma, Hepatocellular
Dual functions of ARP101 in targeting membrane type-1 matrix metalloproteinase: Impact on U87 glioblastoma cell invasion and autophagy signaling.
Carcinoma, Hepatocellular
Expression of matrix metalloproteinases (MMPs) in cultured hepatocellular carcinoma (HCC) cells and surgically resected HCC tissues.
Carcinoma, Hepatocellular
Hepatocarcinoma cell lines down-regulate matrix metalloproteinase-2 expression in human hepatic myofibroblasts.
Carcinoma, Hepatocellular
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Carcinoma, Hepatocellular
Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells.
Carcinoma, Hepatocellular
Matrix Metalloproteinase 1 as a Novel Biomarker for Monitoring Hepatocellular Carcinoma in Liver Transplant Patients.
Carcinoma, Hepatocellular
Membrane palmitoylated protein 3 promotes hepatocellular carcinoma cell migration and invasion via up-regulating matrix metalloproteinase 1.
Carcinoma, Hepatocellular
Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas.
Carcinoma, Hepatocellular
Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
Carcinoma, Hepatocellular
Ribozyme mediated suppression of vascular endothelial growth factor gene expression enhances matrix metalloproteinase 1 expression in a human hepatocellular carcinoma cell line.
Carcinoma, Hepatocellular
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression.
Carcinoma, Hepatocellular
[Expression of MT1-MMP and its significance in rabbit VX2 tumor tissues after transarterial embolization with hydroxyapatite nanoparticles]
Carcinoma, Intraductal, Noninfiltrating
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Carcinoma, Intraductal, Noninfiltrating
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Carcinoma, Intraductal, Noninfiltrating
Immunohistochemical study of matrix metalloproteinase 9 and tissue inhibitor of matrix metalloproteinase 1 in benign and malignant breast tissue--strong expression in intraductal carcinomas of the breast.
Carcinoma, Large Cell
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Carcinoma, Lewis Lung
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Carcinoma, Lobular
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Carcinoma, Neuroendocrine
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Carcinoma, Non-Small-Cell Lung
Insufficient CD100 shedding contributes to suppression of CD8+ T cell activity in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
Carcinoma, Non-Small-Cell Lung
MMP-14 overexpression correlates with poor prognosis in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer.
Carcinoma, Ovarian Epithelial
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma, Papillary
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Carcinoma, Renal Cell
Expression of messenger RNAs for membrane-type 1, 2, and 3 matrix metalloproteinases in human renal cell carcinomas.
Carcinoma, Renal Cell
Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype.
Carcinoma, Renal Cell
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma, Renal Cell
Targeting a Designer TIMP-1 to the Cell Surface for Effective MT1-MMP Inhibition: A Potential Role for the Prion Protein in Renal Carcinoma Therapy.
Carcinoma, Renal Cell
The Precise Diagnosis of Cancer Invasion/Metastasis via 2D Laser Ablation Mass Mapping of Metalloproteinase in Primary Cancer Tissue.
Carcinoma, Squamous Cell
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2.
Carcinoma, Squamous Cell
Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
Carcinoma, Squamous Cell
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Carcinoma, Squamous Cell
Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes.
Carcinoma, Squamous Cell
Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.
Carcinoma, Squamous Cell
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Carcinoma, Squamous Cell
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Carcinoma, Squamous Cell
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Carcinoma, Squamous Cell
Expression of collagenase-1 (MMP-1), collagenase-3 (MMP-13) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in laryngeal squamous cell carcinomas.
Carcinoma, Squamous Cell
Identification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP): a systemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.
Carcinoma, Squamous Cell
Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma.
Carcinoma, Squamous Cell
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Carcinoma, Squamous Cell
Interstitial collagenase gene expression in oral squamous cell carcinoma.
Carcinoma, Squamous Cell
Interstitial collagenase MMP-1 and EMMPRIN in cell lines and in clinical specimens of cervical squamous cell carcinoma.
Carcinoma, Squamous Cell
Matrix metalloproteinase 1: a better biomarker for squamous cell carcinoma by multiple microarray analyses.
Carcinoma, Squamous Cell
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Carcinoma, Squamous Cell
MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines.
Carcinoma, Squamous Cell
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Carcinoma, Squamous Cell
Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
Carcinoma, Squamous Cell
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma, Squamous Cell
[Correlation of membrane type I matrix metalloproteinase (MT1-MMP) expression with clinicomorphological features of tumor front in squamous cell carcinoma of the larynx]
Carcinoma, Squamous Cell
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Carcinoma, Squamous Cell
[Tissue collagenase MMP-14 and endogenous regulators of its activity in the corpus uteri in squamous cell carcinoma of the cervix].
Carcinoma, Transitional Cell
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Carcinoma, Transitional Cell
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Carcinoma, Verrucous
Evaluation of the presence of myofibroblasts and matrix metalloproteinase 1 expression in the stroma of oral verrucous hyperplasia and verrucous carcinoma.
Cardiomyopathy, Dilated
A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure.
Cardiomyopathy, Dilated
PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts.
Cardiovascular Diseases
Anti-apolipoprotein A-1 IgG predicts major cardiovascular events in patients with rheumatoid arthritis.
Cardiovascular Diseases
MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE (MT1-MMP) IDENTIFIED AS A MULTIFUNCTIONAL REGULATOR OF VASCULAR RESPONSES.
Carotid Artery Diseases
Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis.
Carotid Artery Injuries
TGF-?1/Smad signaling, MMP-14, and MSC markers in arterial injury: discovery of the molecular basis of restenosis.
Cerebellar Ataxia
Exclusion of stromelysin-1, stromelysin-2, interstitial collagenase and fibronectin genes as the mutant loci in a family with recessive epidermolysis bullosa dystrophica and a form of cerebellar ataxia.
Cerebral Infarction
[Association of MMP-14 gene polymorphism with cerebral infarction - a case-control study].
Cervical Intraepithelial Neoplasia
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Cholangiocarcinoma
Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts.
Cholecystitis
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Choledochal Cyst
Expression of matrix metalloproteinase 1 and 2 in congenital choledochal cyst and its clinical significance.
Cholera
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Cholestasis
Increased MMP-7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia.
Cholesteatoma
Evaluation of significant gene expression changes in congenital and acquired cholesteatoma.
Cholesteatoma
Localization of matrix metalloproteinase 1 in cholesteatoma and deep meatal skin.
Chondroma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chondrosarcoma
Absence of a correlation between the presence of a single nucleotide polymorphism in the matrix metalloproteinase 1 promoter and outcome in patients of chondrosarcoma.
Chondrosarcoma
Apoptosis signal-regulating kinase 1 is involved in brain-derived neurotrophic factor (BDNF)-enhanced cell motility and matrix metalloproteinase 1 expression in human chondrosarcoma cells.
Chondrosarcoma
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Chondrosarcoma
Expression of membrane type 1 matrix metalloproteinase in human articular cartilage.
Chondrosarcoma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chondrosarcoma
Hyaluronan inhibits IL-1beta-stimulated collagenase production via down-regulation of phosphorylated p38 in SW-1353 human chondrosarcoma cells.
Chondrosarcoma
Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3.
Chondrosarcoma
Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.
Chondrosarcoma
MicroRNA?10b suppresses the migration and invasion of chondrosarcoma cells by targeting brain?derived neurotrophic factor.
Chondrosarcoma, Mesenchymal
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Choriocarcinoma
Overexpressed PAK4 promotes proliferation, migration and invasion of choriocarcinoma.
Chronic Periodontitis
CD40 engagement modulates the production of matrix metalloproteinases by gingival fibroblasts.
Chronic Periodontitis
Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study.
Chronic Periodontitis
Tetracycline inhibition identifies the cellular origin of interstitial collagenases in human periodontal diseases in vivo.
Colitis
"Splitting the matrix": intussusceptive angiogenesis meets MT1-MMP.
Colitis
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.
Colitis, Collagenous
Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression.
Colitis, Ulcerative
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Colonic Neoplasms
Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor.
Colonic Neoplasms
Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity.
Colonic Neoplasms
miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14.
Colonic Neoplasms
Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells.
Colonic Neoplasms
The clinical significance and biological function of tropomyosin 4 in colon cancer.
Colorectal Neoplasms
?-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.
Colorectal Neoplasms
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas.
Colorectal Neoplasms
Clinicopathological and Prognostic Significance of ?5?1-integrin and MMP-14 Expressions in Colorectal Cancer.
Colorectal Neoplasms
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Colorectal Neoplasms
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Colorectal Neoplasms
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation.
Colorectal Neoplasms
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Colorectal Neoplasms
Low collagenase-1 (MMP-1) and MT1-MMP expression levels are favourable survival markers in advanced colorectal carcinoma.
Colorectal Neoplasms
Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
Colorectal Neoplasms
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Colorectal Neoplasms
Plasma concentration of tissue inhibitor of matrix metalloproteinase 1 in patients with colorectal carcinoma.
Colorectal Neoplasms
Preanalytical Interferences Compromise the Clinical Validity of Matrix Metalloproteinase 1 as Marker of Colorectal Cancer.
Colorectal Neoplasms
Profiling markers of prognosis in colorectal cancer.
Colorectal Neoplasms
Prophylactical Low Dose Whole-Liver Irradiation Inhibited Colorectal Liver Metastasis by Regulating Hepatic Niche in Mice.
Colorectal Neoplasms
Relation of MT1-MMP gene expression to outcomes in colorectal cancer.
Colorectal Neoplasms
Reply: Preanalytical Interferences Compromise the Clinical Validity of Matrix Metalloproteinase 1 as Marker of Colorectal Cancer.
Colorectal Neoplasms
Role of matrix metalloproteinases (MMPs) in colorectal cancer.
Colorectal Neoplasms
Serum Matrix-Metalloproteinase-1 is a Bona Fide Prognostic Marker for Colorectal Cancer.
Colorectal Neoplasms
The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer.
Colorectal Neoplasms
The distribution of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal cancer.
Colorectal Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Colorectal Neoplasms
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
Colorectal Neoplasms
[Role of CD44 and MT1-MMP in colorectal cancer invasion and metastasis]
Connective Tissue Diseases
Integration of the NF-kappaB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts.
Corneal Diseases
Collagenase (MMP-1) and TIMP-1 in destructive corneal disease associated with rheumatoid arthritis.
Corneal Neovascularization
Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis).
Corneal Neovascularization
Matrix metalloproteinase 14 modulates signal transduction and angiogenesis in the cornea.
Corneal Neovascularization
Membrane type-1 matrix metalloproteinase potentiates basic fibroblast growth factor-induced corneal neovascularization.
Corneal Neovascularization
MT1-MMP cleavage of the antiangiogenic proteoglycan decorin: role in corneal angiogenesis.
Corneal Neovascularization
MT1-MMP Cleavage of the Antiangiogenic Proteoglycan Decorin: Role in Corneal Angiogenesis: Retraction.
Coronary Artery Disease
Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture.
Craniofacial Abnormalities
Delayed tooth eruption in membrane type-1 matrix metalloproteinase deficient mice.
Craniofacial Abnormalities
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.
Crohn Disease
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Crohn Disease
Relationship between Metalloprotease-7 and -14 and Tissue Inhibitor of Metalloprotease 1 Expression by Mucosal Stromal Cells and Colorectal Cancer Development in Inflammatory Bowel Disease.
Cysts
Effect of dental cyst epithelium-conditioned medium on collagenase production by periodontal ligament fibroblasts.
Cysts
Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease.
Cysts
Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.
Cysts
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
Cysts
Modulation of Matrix Metalloproteinase 14, Tissue Inhibitor of Metalloproteinase 3, Tissue Inhibitor of Metalloproteinase 4, and Inducible Nitric Oxide Synthase in the Development of Periapical Lesions.
Cysts
The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen.
Demyelinating Diseases
Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain.
Dermatitis Herpetiformis
Enhanced expression of interstitial collagenase, stromelysin-1, and urokinase plasminogen activator in lesions of dermatitis herpetiformis.
Dermatitis Herpetiformis
Urokinase plasminogen activator is expressed by basal keratinocytes before interstitial collagenase, stromelysin-1, and laminin-5 in experimentally induced dermatitis herpetiformis lesions.
Dermatitis, Contact
Monocyte/Macrophage MMP-14 Modulates Cell Infiltration and T-Cell Attraction in Contact Dermatitis But Not in Murine Wound Healing.
Dermatomyositis
Expression of specific matrix metalloproteinases in inflammatory myopathies.
Diabetes Mellitus, Type 1
Defining the roles of T cell membrane proteinase and CD44 in type 1 diabetes.
Diabetes Mellitus, Type 1
Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.
Diabetes Mellitus, Type 1
Mechanistic insights into targeting T cell membrane proteinase to promote islet beta-cell rejuvenation in type 1 diabetes.
Diabetes Mellitus, Type 1
MT1-MMP expression in first-trimester placental tissue is upregulated in type 1 diabetes as a result of elevated insulin and tumor necrosis factor-alpha levels.
Diabetes Mellitus, Type 1
Targeting the T-cell membrane type-1 matrix metalloproteinase-CD44 axis in a transferred type 1 diabetes model in NOD mice.
Diabetes Mellitus, Type 1
The skin remodeling in type 1 diabetes and insulin resistance animal models.
Diabetes Mellitus, Type 2
Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population.
Diabetes, Gestational
Fetal Insulin and IGF-II Contribute to Gestational Diabetes Mellitus (GDM)-Associated Up-Regulation of Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) in the Human Feto-Placental Endothelium.
Diabetic Angiopathies
MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE (MT1-MMP) IDENTIFIED AS A MULTIFUNCTIONAL REGULATOR OF VASCULAR RESPONSES.
Diabetic Nephropathies
Collagenase-1 (-1607 1G/2G), Gelatinase-A (-1306 C/T), Stromelysin-1 (-1171 5A/6A) functional promoter polymorphisms in risk prediction of type 2 diabetic nephropathy.
Diabetic Nephropathies
Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats.
Diabetic Retinopathy
Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy.
Distemper
Up-regulation of mRNA for matrix metalloproteinases-9 and -14 in advanced lesions of demyelinating canine distemper leukoencephalitis.
Diverticular Diseases
Increased distribution of collagen type III and reduced expression of matrix metalloproteinase 1 in patients with diverticular disease.
Diverticulum
Genetic variants of tissue inhibitors of matrix metalloproteinase 1 (rs4898) and 2 (rs8179090) in diverticulosis.
Down Syndrome
Enhancement of matrix metalloproteinase (MMP)-2 activity in gingival tissue and cultured fibroblasts from Down's syndrome patients.
Dupuytren Contracture
A common SNP risk variant MT1-MMP causative for Dupuytren's disease has a specific defect in collagenolytic activity.
Dupuytren Contracture
MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction.
Dwarfism
Delayed tooth eruption in membrane type-1 matrix metalloproteinase deficient mice.
Dwarfism
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism.
Dwarfism
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover.
Dysplastic Nevus Syndrome
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Encephalitis
Up-regulation of mRNA for matrix metalloproteinases-9 and -14 in advanced lesions of demyelinating canine distemper leukoencephalitis.
Endometrial Hyperplasia
Localization of MT1-MMP, TIMP-1, TIMP-2, and TIMP-3 messenger RNA in normal, hyperplastic, and neoplastic endometrium. Enhanced expression by endometrial adenocarcinomas is associated with low differentiation.
Endometrial Neoplasms
Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
Endometrial Neoplasms
Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.
Endometrial Neoplasms
RNA interference screening identifies clathrin-B and cofilin-1 as mediators of MT1-MMP in endometrial cancer.
Endometrial Neoplasms
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
Endometrial Neoplasms
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Endometriosis
Analysis of two polymorphisms in the promoter region of matrix metalloproteinase 1 and 3 genes in women with endometriosis.
Endometriosis
Estrogen receptor beta and matrix metalloproteinase 1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosis.
Endometriosis
Expression of interstitial collagenase (matrix metalloproteinase-1) is related to the activity of human endometriotic lesions.
Endometriosis
Matrix metalloproteinase messenger RNA expression in human endometriosis grafts cultured on a chicken chorioallantoic membrane.
Endometriosis
Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium.
Endotoxemia
Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.
Endotoxemia
Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal model.
Epidermolysis Bullosa
[Fibroblast collagenase activity in some types of inherited epidermolysis bullosa]
Epidermolysis Bullosa Dystrophica
Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
Epidermolysis Bullosa Dystrophica
Cleavage of type VII collagen by interstitial collagenase and type IV collagenase (gelatinase) derived from human skin.
Epidermolysis Bullosa Dystrophica
Exclusion of stromelysin-1, stromelysin-2, interstitial collagenase and fibronectin genes as the mutant loci in a family with recessive epidermolysis bullosa dystrophica and a form of cerebellar ataxia.
Epiretinal Membrane
Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy.
Epiretinal Membrane
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Esophageal Neoplasms
Downregulation of RIKP by miR-200a promotes the invasive ability of esophageal cancer cells by upregulating the expression of LIN28 and MMP-14 [Retraction].
Esophageal Neoplasms
Downregulation of RIKP by miR-200a promotes the invasive ability of esophageal cancer cells by upregulating the expression of LIN28 and MMP-14.
Esophageal Neoplasms
Raf kinase inhibitor protein inhibits esophageal cancer cell invasion through downregulation of matrix metalloproteinase expression.
Esophageal Neoplasms
Upregulated expression and activation of membrane?associated proteases in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Interaction of MT1-MMP and laminin-5gamma2 chain correlates with metastasis and invasiveness in human esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Matrix metalloproteinase 1, 3, and 9 polymorphisms and esophageal squamous cell carcinoma risk.
Esophageal Squamous Cell Carcinoma
Matrix metalloproteinase-14 (MMP-14) downregulation inhibits esophageal squamous cell carcinoma cell migration, invasion, and proliferation.
Esophageal Squamous Cell Carcinoma
MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China.
Esophageal Squamous Cell Carcinoma
Plasma matrix metalloproteinase 1 improves the detection and survival prediction of esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Upregulated expression and activation of membrane?associated proteases in esophageal squamous cell carcinoma.
Fasciculation
Regulatory network of differentially expressed genes in metastatic osteosarcoma.
Fetal Growth Retardation
Matrix metalloproteinase 1 in pre-eclampsia and fetal growth restriction: reduced gene expression in decidual tissue and protein expression in extravillous trophoblasts.
Fetal Growth Retardation
Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) Regulates Trophoblast Functions and Is Reduced in Fetal Growth Restriction.
Fibromatosis, Aggressive
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Fibrosarcoma
(-)Epigallocatechin-3-gallate directly inhibits MT1-MMP activity, leading to accumulation of nonactivated MMP-2 at the cell surface.
Fibrosarcoma
1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
Fibrosarcoma
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Fibrosarcoma
A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression.
Fibrosarcoma
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Fibrosarcoma
An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy.
Fibrosarcoma
Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells.
Fibrosarcoma
Cleavage of lumican by membrane-type matrix metalloproteinase-1 abrogates this proteoglycan-mediated suppression of tumor cell colony formation in soft agar.
Fibrosarcoma
Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration.
Fibrosarcoma
CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer.
Fibrosarcoma
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.
Fibrosarcoma
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).
Fibrosarcoma
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.
Fibrosarcoma
Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts.
Fibrosarcoma
Dual-functions of miR-373 and miR-520c by differently regulating the activities of MMP2 and MMP9.
Fibrosarcoma
GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.
Fibrosarcoma
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion.
Fibrosarcoma
Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression.
Fibrosarcoma
Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.
Fibrosarcoma
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression.
Fibrosarcoma
Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.
Fibrosarcoma
Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains.
Fibrosarcoma
Mapping proteolytic cancer cell-extracellular matrix interfaces.
Fibrosarcoma
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.
Fibrosarcoma
Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface.
Fibrosarcoma
MT1-MMP prevents growth inhibition by three dimensional fibronectin matrix.
Fibrosarcoma
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion.
Fibrosarcoma
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
Fibrosarcoma
Neutrophil-derived serine proteinases enhance membrane type-1 matrix metalloproteinase-dependent tumor cell invasion.
Fibrosarcoma
Non-destructive and selective imaging of the functionally active, pro-invasive membrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells.
Fibrosarcoma
Oligomerization through hemopexin and cytoplasmic domains regulates the activity and turnover of membrane-type 1 matrix metalloproteinase.
Fibrosarcoma
Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP.
Fibrosarcoma
Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and migration.
Fibrosarcoma
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface.
Fibrosarcoma
Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes.
Fibrosarcoma
Targeting a Designer TIMP-1 to the Cell Surface for Effective MT1-MMP Inhibition: A Potential Role for the Prion Protein in Renal Carcinoma Therapy.
Fibrosarcoma
The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form.
Fibrosarcoma
The C-terminal domain of tissue inhibitor of metalloproteinases-2 is required for cell binding but not for antimetalloproteinase activity.
Fibrosarcoma
The Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity.
Fibrosarcoma
The role of MT2-MMP in cancer progression.
Fibrosarcoma
TIMP-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.
Gastritis
Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer.
Gastrointestinal Neoplasms
Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers.
Gingival Pocket
Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation.
Gingivitis
Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study.
Glaucoma
Differential expression of matrix metalloproteinases in monkey eyes with experimental glaucoma or optic nerve transection.
Glaucoma
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes.
Glioblastoma
A role for MT1-MMP as a cell death sensor/effector through the regulation of endoplasmic reticulum stress in U87 glioblastoma cells.
Glioblastoma
Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-?B-Mediated Mechanism.
Glioblastoma
Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Glioblastoma
Cell-based evidence for aminopeptidase N/CD13 inhibitor actinonin targeting of MT1-MMP-mediated proMMP-2 activation.
Glioblastoma
Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells.
Glioblastoma
Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression.
Glioblastoma
Dual functions of ARP101 in targeting membrane type-1 matrix metalloproteinase: Impact on U87 glioblastoma cell invasion and autophagy signaling.
Glioblastoma
Dual-functions of miR-373 and miR-520c by differently regulating the activities of MMP2 and MMP9.
Glioblastoma
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Glioblastoma
Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.
Glioblastoma
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Glioblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Glioblastoma
Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells.
Glioblastoma
Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells.
Glioblastoma
Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains.
Glioblastoma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Glioblastoma
Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter.
Glioblastoma
Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling.
Glioblastoma
Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision.
Glioblastoma
New photodynamic molecular beacons (PMB) as potential cancer-targeted agents in PDT.
Glioblastoma
Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells.
Glioblastoma
Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma.
Glioblastoma
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Glioblastoma
The Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity.
Glioblastoma
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Glioblastoma
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Glioblastoma
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Glioblastoma
Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
Glioblastoma
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Glioma
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells.
Glioma
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Glioma
Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression.
Glioma
Centrosomal pericentrin is a direct cleavage target of membrane type-1 matrix metalloproteinase in humans but not in mice: potential implications for tumorigenesis.
Glioma
Co-expression of MMP-14 and MMP-19 predicts poor survival in human glioma.
Glioma
Discriminating healthy from tumor and necrosis tissue in rat brain tissue samples by Raman spectral imaging.
Glioma
Enolase-phosphatase 1 as a novel potential malignant glioma indicator promotes cell proliferation and migration.
Glioma
Expressions of matrix metalloproteinase-7 and matrix metalloproteinase-14 associated with the activation of extracellular signal-regulated kinase1/2 in human brain gliomas of different pathological grades.
Glioma
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas.
Glioma
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Glioma
Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+ exchanger isoform 1.
Glioma
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Glioma
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Glioma
Induction of matrix metalloproteinase-1 and glioma cell motility by nitric oxide.
Glioma
Induction of membrane-type-1 matrix metalloproteinase by epidermal growth factor-mediated signaling in gliomas.
Glioma
KIF1B promotes glioma migration and invasion via cell surface localization of MT1-MMP.
Glioma
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Glioma
Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.
Glioma
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Glioma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Glioma
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.
Glioma
Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter.
Glioma
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Glioma
MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10.
Glioma
Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression.
Glioma
miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.
Glioma
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Glioma
Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP).
Glioma
NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway.
Glioma
Probing the infiltrating character of brain tumors: inhibition of RhoA/ROK-mediated CD44 cell surface shedding from glioma cells by the green tea catechin EGCg.
Glioma
Protein kinase C-mediated in vitro invasion of human glioma cells through extracellular-signal-regulated kinase and ornithine decarboxylase.
Glioma
Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism.
Glioma
SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.
Glioma
Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models.
Glioma
Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.
Glioma
The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKgamma/NF-kappaB-dependent pathway.
Glioma
The value and correlation between PRL-3 expression and matrix metalloproteinase activity and expression in human gliomas.
Glioma
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.
Glioma
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Glioma
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Glioma
Up-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis.
Glomerulonephritis
Characterization of the transcriptional regulation of the human MT1-MMP gene and association of risk reduction for focal-segmental glomerulosclerosis with two functional promoter SNPs.
Glomerulonephritis
Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.
Glomerulonephritis
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis.
Granuloma
Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.
Granuloma
Cellular source of collagenase and TIMP-1 in carrageenin-induced granuloma.
Granuloma
Collagenase-3 induction in rat lung fibroblasts requires the combined effects of tumor necrosis factor-alpha and 12-lipoxygenase metabolites: a model of macrophage-induced, fibroblast-driven extracellular matrix remodeling during inflammatory lung injury.
Granuloma
Interstitial collagenase (MMP-1), gelatinase (MMP-2) and stromelysin (MMP-3) released by human fibroblasts cultured on acellular sarcoid granulomas (sarcoid matrix complex, SMC).
Granuloma
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.
Granuloma Annulare
Expression of interstitial collagenase, 92-kDa gelatinase, and tissue inhibitor of metalloproteinases-1 in granuloma annulare and necrobiosis lipoidica diabeticorum.
Hajdu-Cheney Syndrome
Mutation of Membrane Type-1 Metalloproteinase, MT1-MMP, Causes the Multicentric Osteolysis and Arthritis Disease Winchester Syndrome.
Hearing Loss
MMP-14 (MT1-MMP) Is a Biomarker of Surgical Outcome and a Potential Mediator of Hearing Loss in Patients With Vestibular Schwannomas.
Heart Failure
Controlled Release of Matrix Metalloproteinase 1 with or wiyhout Skeletal Myoblasts Transplantion Improves Cardiac Function of Rat Hearts with Chronic Myocardial Infarction.
Heart Failure
Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat.
Heart Failure
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Hepatitis
Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes.
Hepatitis C, Chronic
Longitudinal evaluation of a fibrosis index combining MMP-1 and PIIINP compared with MMP-9, TIMP-1 and hyaluronic acid in patients with chronic hepatitis C treated by interferon-alpha and ribavirin.
Hepatitis, Chronic
Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes.
Histiocytic Sarcoma
Matrix metalloproteinases expression in spontaneous canine histiocytic sarcomas and its xenograft model.
Histiocytoma, Malignant Fibrous
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Histiocytosis, Sinus
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Hydrocephalus
MT1-MMP deficiency leads to defective ependymal cell maturation, impaired ciliogenesis, and hydrocephalus.
Hyperalgesia
Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain.
Hyperglycemia
Fetal Insulin and IGF-II Contribute to Gestational Diabetes Mellitus (GDM)-Associated Up-Regulation of Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) in the Human Feto-Placental Endothelium.
Hyperlipidemias
Cleavage and functional loss of human apolipoprotein E by digestion of matrix metalloproteinase-14.
Hyperostosis
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Hypersensitivity
Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter.
Hypertension
Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients.
Hypertension
Effects of early and late chronic pressure overload on extracellular matrix remodeling.
Hypertension
Estrogen deficiency-induced alterations of vascular MMP-2, MT1-MMP, and TIMP-2 in ovariectomized rats.
Hypertension
Estrogen effects on MMP-13 and MMP-14 regulation of left ventricular mass in Dahl salt-induced hypertension.
Hypertension
Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
Hypertension
[Association of MMP-14 gene polymorphism with cerebral infarction - a case-control study].
Hypertension, Pulmonary
Acute and chronic hypoxia as well as 7-day recovery from chronic hypoxia affects the distribution of pulmonary mast cells and their MMP-13 expression in rats.
Hypertrophy, Left Ventricular
Leukocyte matrix metalloproteinase and tissue inhibitor gene expression patterns in children with primary hypertension.
Infections
Assay of extracellular matrix degradation and transmigration of chicken peripheral blood mononuclear cells after infection with genotype VII Newcastle disease virus in vitro.
Infections
Balance between polyoma enhancing activator 3 and activator protein 1 regulates Helicobacter pylori-stimulated matrix metalloproteinase 1 expression.
Infections
Expression of a progelatinase activator (MT1-MMP) in human fetal membranes.
Infections
Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality.
Infections
Interaction between hepatic membrane type 1 matrix metalloproteinase and acireductone dioxygenase 1 regulates hepatitis C virus infection.
Infections
Matrix metalloproteinase 14 regulates HSV-1 infection in neuroblastoma cells.
Infections
Matrix metalloproteinase-14 regulates collagen degradation and migration of mononuclear cells during infection with genotype VII Newcastle disease virus.
Infections
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.
Infections
MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy.
Infections
Rapid Proteome Changes in Plasma and Cerebrospinal Fluid Following Bacterial Infection in Preterm Newborn Pigs.
Infections
Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase.
Infections
Virus-Mediated Metalloproteinase 1 Induction Revealed by Transcriptome Profiling of Bovine Herpesvirus 4-Infected Bovine Endometrial Stromal Cells.
Inflammatory Bowel Diseases
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.
Inflammatory Bowel Diseases
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Inflammatory Bowel Diseases
Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype.
Inflammatory Breast Neoplasms
Membrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer.
Influenza, Human
Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality.
Insulin Resistance
The skin remodeling in type 1 diabetes and insulin resistance animal models.
interstitial collagenase deficiency
Correction to: Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferation.
interstitial collagenase deficiency
Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferation.
interstitial collagenase deficiency
Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques.
interstitial collagenase deficiency
MT1-MMP and Type II Collagen Specify Skeletal Stem Cells and Their Bone and Cartilage Progeny.
interstitial collagenase deficiency
MT1-MMP deficiency leads to defective ependymal cell maturation, impaired ciliogenesis, and hydrocephalus.
interstitial collagenase deficiency
MT1-MMP promotes vascular smooth muscle dedifferentiation through LRP1 processing.
interstitial collagenase deficiency
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover.
interstitial collagenase deficiency
MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth.
interstitial collagenase deficiency
Multifunctional roles of MT1-MMP in myofiber formation and morphostatic maintenance of skeletal muscle.
interstitial collagenase deficiency
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.
Intervertebral Disc Degeneration
Genetic Dimension of Intervertebral Disc Degeneration: Polymorphism of Matrix Metalloproteinase 1 and 3 in the North Iranian Population.
Intervertebral Disc Degeneration
Increased MMP-2 activity during intervertebral disc degeneration is correlated to MMP-14 levels.
Intervertebral Disc Degeneration
[Effect of Acupotomy Lysis at Cervical Acupoints on Expression of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinase 1 and Changes of Pulpiform Nucleus Ultrastructure in Rats with Degenerated Cervical Intervertebral Discs].
Intervertebral Disc Displacement
Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients.
Intervertebral Disc Displacement
The relation of matrix metalloproteinase 1, 2, 3 expressions with clinical and radiological findings in primary and recurrent lumbar disc herniations.
Ischemic Attack, Transient
Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia.
Jaw Cysts
Inhibition of matrix metalloproteinase-1 by dichloromethylene bisphosphonate (clodronate).
Joint Diseases
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis.
Joint Diseases
Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts.
Joint Diseases
Increased serum stromelysin-1 levels in systemic lupus erythematosus: lack of correlation with disease activity.
Keloid
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progression.
Keratoconus
Collagenolytic proteinases in keratoconus.
Keratoconus
EMMPRIN and MMP-1 in keratoconus.
Keratoconus
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in normal and keratoconus corneas.
Keratoconus
Is the corneal degradation in keratoconus caused by matrix-metalloproteinases?
Keratosis, Actinic
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Kidney Diseases
Characterization of the transcriptional regulation of the human MT1-MMP gene and association of risk reduction for focal-segmental glomerulosclerosis with two functional promoter SNPs.
Kidney Neoplasms
Membrane type-2 matrix metalloproteinases improve the progression of renal cell cancer.
Laryngeal Neoplasms
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Laryngeal Neoplasms
Expression of mRNA for membrane-type 1, 2, and 3 matrix metalloproteinases in human laryngeal cancer.
Leg Ulcer
Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers.
Leiomyoma
Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer.
Leukemia
Identification of novel target proteins in sebaceous gland carcinoma.
Leukemia
The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity.
Leukemia
The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis.
Leukemia
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
Leukemia, Monocytic, Acute
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
Leukemia, Myeloid, Acute
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-?.
Lichen Planus, Oral
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Lichen Planus, Oral
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Lipodystrophy
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism.
Liver Cirrhosis
Assessing matrix metalloproteinase expression and activity in hepatocellular carcinomas.
Liver Cirrhosis
Collagenases and liver fibrosis.
Liver Cirrhosis
Diagnostic potential of serum direct markers and non-invasive fibrosis models in patients with chronic hepatitis B.
Liver Cirrhosis
Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect.
Liver Cirrhosis
Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat.
Liver Cirrhosis
Effects of a plasmid expressing antisense tissue inhibitor of metalloproteinase-1 on liver fibrosis in rats.
Liver Cirrhosis
Endoplasmic reticulum oxidase 1? is critical for collagen secretion from and membrane type 1-matrix metalloproteinase levels in hepatic stellate cells.
Liver Cirrhosis
Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis.
Liver Cirrhosis
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis.
Liver Cirrhosis
Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver.
Liver Cirrhosis
Expression pattern of matrix metalloproteinases-13 in a rat model of alcoholic liver fibrosis.
Liver Cirrhosis
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis.
Liver Cirrhosis
Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride.
Liver Cirrhosis
Longitudinal evaluation of a fibrosis index combining MMP-1 and PIIINP compared with MMP-9, TIMP-1 and hyaluronic acid in patients with chronic hepatitis C treated by interferon-alpha and ribavirin.
Liver Cirrhosis
Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis.
Liver Cirrhosis
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats.
Liver Cirrhosis
Reversal of established liver fibrosis by IC-2-engineered mesenchymal stem cell sheets.
Liver Cirrhosis
Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis.
Liver Cirrhosis
Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice.
Liver Cirrhosis
Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis.
Liver Cirrhosis
Tissue inhibitors of metalloproteinases: role in liver fibrosis and alcoholic liver disease.
Liver Cirrhosis
[Gene expression of interstitial collagenase MMP-13 in progressive phase of rat liver fibrosis induced by ethanol]
Liver Cirrhosis
[Recombinant adenovirus Ad-human matrix metalloproteinase 1 transfecting bone marrow mesenchymal stem cells of rats in vitro].
Liver Cirrhosis
[Therapeutic effect of BMSCs with over-expressed MMP1 on liver fibrosis].
Liver Neoplasms
MT1-MMP Responsive Doxorubicin Conjugated Poly(lactic-co-glycolic Acid)/Poly(styrene-alt-maleic Anhydride) Core/Shell Microparticles for Intrahepatic Arterial Chemotherapy of Hepatic Cancer.
Lung Diseases
Matrix metalloproteinases in lung diseases.
Lung Injury
Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.
Lung Neoplasms
An approach to studying lung cancer-related proteins in human blood.
Lung Neoplasms
Changes in the expression of matrix proteases and of the transcription factor c-Ets-1 during progression of precancerous bronchial lesions.
Lung Neoplasms
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Lung Neoplasms
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Lung Neoplasms
Expression of extracellular matrix molecules in brain metastasis.
Lung Neoplasms
Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.
Lung Neoplasms
Identification of Wnt pathway, uPA, PAI-1, MT1-MMP, S100A4 and CXCR4 associated with enhanced metastasis of human large cell lung cancer by DNA microarray.
Lung Neoplasms
Insufficient CD100 shedding contributes to suppression of CD8+ T cell activity in non-small cell lung cancer.
Lung Neoplasms
Letter regarding "MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies" by Wu KP et al.
Lung Neoplasms
Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer.
Lung Neoplasms
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Lung Neoplasms
Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
Lung Neoplasms
MMP-14 overexpression correlates with poor prognosis in non-small cell lung cancer.
Lung Neoplasms
MMP1 rs1799750 Single Nucleotide Polymorphism and Lung Cancer Risk: A Meta-analysis.
Lung Neoplasms
MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies.
Lung Neoplasms
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer.
Lung Neoplasms
[Association of MMP1 -1607(1G>2G)single nucleotide polymorphism with susceptibility to lung cancer in Northwestern Chinese population of Han nationality]
Lung Neoplasms
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
Lung Neoplasms
[MiR-373-3p Promotes Invasion and Metastasis of Lung Adenocarcinoma Cells].
Lupus Erythematosus, Systemic
Increased serum stromelysin-1 levels in systemic lupus erythematosus: lack of correlation with disease activity.
Lyme Disease
Borrelia burgdorferi-induced expression of matrix metalloproteinases from human chondrocytes requires mitogen-activated protein kinase and Janus kinase/signal transducer and activator of transcription signaling pathways.
Lymphatic Metastasis
A role of MMP-14 in the regulation of invasiveness of nasopharyngeal carcinoma.
Lymphatic Metastasis
Analysis of MT1-MMP and MMP2 expression in human gastric cancers.
Lymphatic Metastasis
Association between immunohistochemical expression of matrix metalloproteinases and metastasis in oral squamous cell carcinoma: Systematic review and meta-analysis.
Lymphatic Metastasis
Association of BCSC-1 and MMP-14 with human breast cancer.
Lymphatic Metastasis
Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.
Lymphatic Metastasis
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Lymphatic Metastasis
Clinical significance of MT1-MMP mRNA expression in breast cancer.
Lymphatic Metastasis
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Lymphatic Metastasis
Clinicopathological and Prognostic Significance of ?5?1-integrin and MMP-14 Expressions in Colorectal Cancer.
Lymphatic Metastasis
Decreased MT1-MMP in gastric cancer suppressed cell migration and invasion via regulating MMPs and EMT.
Lymphatic Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Lymphatic Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Lymphatic Metastasis
Expression of membrane type 1-matrix metalloproteinase in laryngeal carcinoma.
Lymphatic Metastasis
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Lymphatic Metastasis
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Lymphatic Metastasis
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Lymphatic Metastasis
Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.
Lymphatic Metastasis
Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material.
Lymphatic Metastasis
Matrix metalloproteinase-14 expression and its prognostic value in cervical carcinoma.
Lymphatic Metastasis
Membrane-type 1 matrix metalloproteinase enhances lymph node metastasis of gastric cancer.
Lymphatic Metastasis
MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis.
Lymphatic Metastasis
Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
Lymphatic Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Lymphatic Metastasis
Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer.
Lymphatic Metastasis
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer.
Lymphatic Metastasis
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Lymphatic Metastasis
[Significance of membrane type-1 matrix metalloproteinase expression in breast cancer]
Lymphoma
Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases.
Lymphoma
CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion.
Lymphoma, B-Cell
Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/?-catenin signaling pathways.
Macular Degeneration
Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium implications for age-related macular degeneration.
Medulloblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Medulloblastoma
MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells.
Medulloblastoma
Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype.
Melanoma
A novel synthetic oleanane triterpenoid suppresses adhesion, migration, and invasion of highly metastatic melanoma cells by modulating gelatinase signaling axis.
Melanoma
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Melanoma
Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion.
Melanoma
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts.
Melanoma
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Melanoma
Cloning and characterization of human tumor cell interstitial collagenase.
Melanoma
Control of melanoma invasiveness by anticollagenolytic agents: a reappraisal of an old concept.
Melanoma
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.
Melanoma
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Melanoma
Decreased expression levels of cell cycle regulators and matrix metalloproteinases in melanoma from RET-transgenic mice by single irradiation of non-equilibrium atmospheric pressure plasmas.
Melanoma
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.
Melanoma
Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein.
Melanoma
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Melanoma
Expression and distribution of MMPs and TIMPs in human uveal melanoma.
Melanoma
Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-beta.
Melanoma
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Melanoma
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Melanoma
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo.
Melanoma
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Melanoma
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Melanoma
HIF1? and HIF2? independently activate SRC to promote melanoma metastases.
Melanoma
High collagenase-1 expression correlates with a favourable chemoimmunotherapy response in human metastatic melanoma.
Melanoma
High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanoma.
Melanoma
High serum levels of matrix metalloproteinase-9 and matrix metalloproteinase-1 are associated with rapid progression in patients with metastatic melanoma.
Melanoma
High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells.
Melanoma
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Melanoma
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Melanoma
Immunolocalisation studies of matrix metalloproteinases-1, -2 and -3 in human melanoma.
Melanoma
In melanoma, beta-catenin is a suppressor of invasion.
Melanoma
In vivo antitumoral effect of 4-nerolidylcatechol (4-NC) in NRAS-mutant human melanoma.
Melanoma
Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.
Melanoma
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
Melanoma
Interdependency of cell adhesion, force generation and extracellular proteolysis in matrix remodeling.
Melanoma
Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.
Melanoma
Intracellular processing and activation of membrane type 1 matrix metalloprotease depends on its partitioning into lipid domains.
Melanoma
Invasive potential of melanoma cells correlates with the expression of MT1-MMP and regulated by modulating its association with motility receptors via N-glycosylation on the receptors.
Melanoma
Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism.
Melanoma
Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.
Melanoma
Lumican Inhibits In Vivo Melanoma Metastasis by Altering Matrix-Effectors and Invadopodia Markers.
Melanoma
Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity.
Melanoma
Lumican: a new inhibitor of matrix metalloproteinase-14 activity.
Melanoma
Matrix-directed regulation of pericellular proteolysis and tumor progression.
Melanoma
Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growth.
Melanoma
MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.
Melanoma
MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1.
Melanoma
Non-destructive and selective imaging of the functionally active, pro-invasive membrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells.
Melanoma
Noncanonical Activation of Notch1 Protein by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Controls Melanoma Cell Proliferation.
Melanoma
Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
Melanoma
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
Melanoma
Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain.
Melanoma
RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.
Melanoma
Role of ?-catenin signaling in the anti-invasive effect of the omega-3 fatty acid DHA in human melanoma cells.
Melanoma
Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes.
Melanoma
Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.
Melanoma
Selective modulation of collagenase 1 gene expression by the chemotherapeutic agent doxorubicin.
Melanoma
Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities.
Melanoma
Targeting Extracellular Matrix Remodeling restores BRAF Inhibitor Sensitivity in BRAFi Resistant Melanoma.
Melanoma
The alternatively spliced RECK transcript variant 3 is a predictor of poor survival for melanoma patients being upregulated in aggressive cell lines and modulating MMP gene expression in vitro.
Melanoma
The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs.
Melanoma
The membrane tethered matrix metalloproteinase MT1-MMP at the forefront of melanoma cell invasion and metastasis.
Melanoma
The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways.
Melanoma
The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination.
Melanoma
Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
Melanoma
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Melanoma
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
Melanoma, Experimental
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Meningioma
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
MERRF Syndrome
Mitochondrial DNA Mutation-Elicited Oxidative Stress, Oxidative Damage, and Altered Gene Expression in Cultured Cells of Patients with MERRF Syndrome.
MERRF Syndrome
Upregulation of Matrix Metalloproteinase 1 and Disruption of Mitochondrial Network in Skin Fibroblasts of Patients with MERRF Syndrome.
Mesothelioma
ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: A comparison between mesothelioma and mesothelial cells.
Mesothelioma
Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases.
Mesothelioma
MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.
Mesothelioma, Malignant
MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.
Mouth Neoplasms
Expression of MMP-14 and prognosis in digestive system carcinoma: a meta-analysis and databases validation.
Mouth Neoplasms
Moesin regulates the motility of oral cancer cells via MT1-MMP and E-cadherin/p120-catenin adhesion complex.
Mouth Neoplasms
Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer.
Multiple Myeloma
Metalloproteinases in multiple myeloma: production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells.
Multiple Sclerosis
Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.
Multiple Sclerosis
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Multiple Sclerosis
Modulation of monocytes matrix metalloproteinase-2, MT1-MMP and TIMP-2 by interferon-gamma and -beta: implications to multiple sclerosis.
Muscular Dystrophies
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Muscular Dystrophies
Multifunctional roles of MT1-MMP in myofiber formation and morphostatic maintenance of skeletal muscle.
Myocardial Infarction
Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction.
Myocardial Infarction
Controlled Release of Matrix Metalloproteinase 1 with or wiyhout Skeletal Myoblasts Transplantion Improves Cardiac Function of Rat Hearts with Chronic Myocardial Infarction.
Myocardial Infarction
Direct Regulation of Membrane Type-1 Matrix Metalloproteinase Following Myocardial Infarction Causes Changes in Survival, Cardiac Function and Remodeling.
Myocardial Infarction
HETEROGENEITY IN MT1-MMP ACTIVITY WITH ISCHEMIA-REPERFUSION AND PREVIOUS MYOCARDIAL INFARCTION: RELATION TO REGIONAL MYOCARDIAL FUNCTION.
Myocardial Infarction
Matrix metalloproteinase 1 promoter polymorphisms and risk of myocardial infarction: a case-control study in a Spanish population.
Myocardial Infarction
Relationship of MMP-14 and TIMP-3 expression with macrophage activation and human atherosclerotic plaque vulnerability.
Myocardial Ischemia
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.
Myopathy, Central Core
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Myopia
Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments.
Myopia
Single Nucleotide Polymorphisms in Promoter Region of Matrix Metalloproteinase 1, 2, and 3 in Japanese with High Myopia.
Myositis
Expression of specific matrix metalloproteinases in inflammatory myopathies.
Myositis, Inclusion Body
Expression of specific matrix metalloproteinases in inflammatory myopathies.
Myringosclerosis
Serum matrix metalloproteinases and tympanosclerosis.
Myxoma
Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas.
Nasopharyngeal Carcinoma
A role of MMP-14 in the regulation of invasiveness of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Matrix metalloproteinase 1 promotes tumorigenesis and inhibits the sensitivity to 5-fluorouracil of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Matrix metalloproteinase-1 (MMP-1) rs1799750 polymorphism is associated with nasopharyngeal carcinoma (NPC) risk.
Nasopharyngeal Carcinoma
Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins.
Necrobiosis Lipoidica
Expression of interstitial collagenase, 92-kDa gelatinase, and tissue inhibitor of metalloproteinases-1 in granuloma annulare and necrobiosis lipoidica diabeticorum.
Neoplasm Metastasis
A high throughput fluorogenic substrate for interstitial collagenase (MMP-1) and gelatinase (MMP-9).
Neoplasm Metastasis
A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases.
Neoplasm Metastasis
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Neoplasm Metastasis
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Neoplasm Metastasis
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasm Metastasis
Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2.
Neoplasm Metastasis
Alpha V integrin prolongs collagenase production through Jun activation binding protein 1.
Neoplasm Metastasis
An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer.
Neoplasm Metastasis
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Neoplasm Metastasis
Analysis of MT1-MMP and MMP2 expression in human gastric cancers.
Neoplasm Metastasis
Association between immunohistochemical expression of matrix metalloproteinases and metastasis in oral squamous cell carcinoma: Systematic review and meta-analysis.
Neoplasm Metastasis
Association of BCSC-1 and MMP-14 with human breast cancer.
Neoplasm Metastasis
Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells.
Neoplasm Metastasis
Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.
Neoplasm Metastasis
Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.
Neoplasm Metastasis
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Neoplasm Metastasis
CircMMP1 promotes colorectal cancer growth and metastasis by sponging miR-1238 and upregulating MMP family expression.
Neoplasm Metastasis
CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer.
Neoplasm Metastasis
Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular carcinoma.
Neoplasm Metastasis
Clinical significance and prognostic value of S100A4 and matrix metalloproteinase-14 in patients with organ-confined bladder cancer.
Neoplasm Metastasis
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Neoplasm Metastasis
Clinical significance of MT1-MMP mRNA expression in breast cancer.
Neoplasm Metastasis
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Neoplasm Metastasis
Clinicopathological and Prognostic Significance of ?5?1-integrin and MMP-14 Expressions in Colorectal Cancer.
Neoplasm Metastasis
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Neoplasm Metastasis
Complete restoration of cell surface activity of transmembrane-truncated MT1-MMP by a glycosylphosphatidylinositol anchor. Implications for MT1-MMP-mediated prommp2 activation and collagenolysis in three-dimensions.
Neoplasm Metastasis
Control of MT1-MMP transport by atypical PKC during breast-cancer progression.
Neoplasm Metastasis
Conversion of stationary to invasive tumor initiating cells (TICs): role of hypoxia in membrane type 1-matrix metalloproteinase (MT1-MMP) trafficking.
Neoplasm Metastasis
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Neoplasm Metastasis
DCLK1 Plays a Metastatic-Promoting Role in Human Breast Cancer Cells.
Neoplasm Metastasis
Decreased MT1-MMP in gastric cancer suppressed cell migration and invasion via regulating MMPs and EMT.
Neoplasm Metastasis
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Neoplasm Metastasis
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Neoplasm Metastasis
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.
Neoplasm Metastasis
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasm Metastasis
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Differential localization of MT1-MMP in human prostate cancer tissue: Role of IGF-1R in MT1-MMP expression.
Neoplasm Metastasis
Differentiated expression of membrane type metalloproteinases (MMP-14, MMP-15) and pro-MMP2 in laryngeal squamous cell carcinoma. A novel mechanism.
Neoplasm Metastasis
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Neoplasm Metastasis
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Neoplasm Metastasis
Dual-functions of miR-373 and miR-520c by differently regulating the activities of MMP2 and MMP9.
Neoplasm Metastasis
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Neoplasm Metastasis
ELK3 Expression Correlates With Cell Migration, Invasion, and Membrane Type 1-Matrix Metalloproteinase Expression in MDA-MB-231 Breast Cancer Cells.
Neoplasm Metastasis
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Neoplasm Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Neoplasm Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Neoplasm Metastasis
Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.
Neoplasm Metastasis
Evaluation of stromal metalloproteinases and vascular endothelial growth factors in a spontaneous metastasis model.
Neoplasm Metastasis
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Neoplasm Metastasis
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Neoplasm Metastasis
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Neoplasm Metastasis
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Neoplasm Metastasis
Expression of extracellular matrix molecules in brain metastasis.
Neoplasm Metastasis
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Neoplasm Metastasis
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Neoplasm Metastasis
Expression of membrane type 1-matrix metalloproteinase in laryngeal carcinoma.
Neoplasm Metastasis
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.
Neoplasm Metastasis
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Neoplasm Metastasis
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Neoplasm Metastasis
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas.
Neoplasm Metastasis
Expression of the reversion-inducing cysteine-rich protein with Kazal motifs and matrix metalloproteinase-14 in neuroblastoma and the role in tumour metastasis.
Neoplasm Metastasis
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Neoplasm Metastasis
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Neoplasm Metastasis
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Neoplasm Metastasis
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Neoplasm Metastasis
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Neoplasm Metastasis
Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis.
Neoplasm Metastasis
Gold Nanoparticle-Based Fluorescent Contrast Agent with Enhanced Sensitivity.
Neoplasm Metastasis
Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.
Neoplasm Metastasis
High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanoma.
Neoplasm Metastasis
High serum MMP-14 predicts worse survival in gastric cancer.
Neoplasm Metastasis
Identification of Wnt pathway, uPA, PAI-1, MT1-MMP, S100A4 and CXCR4 associated with enhanced metastasis of human large cell lung cancer by DNA microarray.
Neoplasm Metastasis
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Neoplasm Metastasis
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Neoplasm Metastasis
Immunolocalization of matrix metalloproteinases and their inhibitors in clinical specimens of bone metastasis from breast carcinoma.
Neoplasm Metastasis
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Neoplasm Metastasis
Increased Aggressiveness of Human Prostate PC-3 Tumor Cells Expressing Cell Surface Localized Membrane Type-1 Matrix Metalloproteinase (MT1-MMP).
Neoplasm Metastasis
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression.
Neoplasm Metastasis
Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells.
Neoplasm Metastasis
Interaction of MT1-MMP and laminin-5gamma2 chain correlates with metastasis and invasiveness in human esophageal squamous cell carcinoma.
Neoplasm Metastasis
Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.
Neoplasm Metastasis
Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression.
Neoplasm Metastasis
Interstitial collagenase gene expression in colonic neoplasia.
Neoplasm Metastasis
Intrahepatic metastasis by orthotopic implantation of a fragment of murine hepatoma and its related molecules.
Neoplasm Metastasis
Intratumoral concentrations of tissue inhibitor of matrix metalloproteinase 1 in patients with gastric carcinoma a new biomartker for invasion and its impact on survival.
Neoplasm Metastasis
Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.
Neoplasm Metastasis
LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells.
Neoplasm Metastasis
LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.
Neoplasm Metastasis
Loss of P53 facilitates invasion and metastasis of prostate cancer cells.
Neoplasm Metastasis
Loss of retinal cadherin facilitates mammary tumor progression and metastasis.
Neoplasm Metastasis
Matrix metalloprotease-14 is a target enzyme for detecting peritoneal metastasis in gastric cancer.
Neoplasm Metastasis
Matrix metalloproteinase (MMP) expression by differentiated thyroid carcinoma of children and adolescents.
Neoplasm Metastasis
Matrix Metalloproteinase 1 promotes tumor formation and lung metastasis in an intratibial injection osteosarcoma mouse model.
Neoplasm Metastasis
Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer.
Neoplasm Metastasis
Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material.
Neoplasm Metastasis
Matrix metalloproteinase-14 expression and its prognostic value in cervical carcinoma.
Neoplasm Metastasis
Matrix Metalloproteinase-14 Is a Negative Prognostic Marker for Patients with Gastric Cancer.
Neoplasm Metastasis
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Neoplasm Metastasis
Mechanism of metastasis by membrane type 1-matrix metalloproteinase in hepatocellular carcinoma.
Neoplasm Metastasis
Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo.
Neoplasm Metastasis
Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses.
Neoplasm Metastasis
Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis.
Neoplasm Metastasis
Membrane-type 1 matrix metalloproteinase enhances lymph node metastasis of gastric cancer.
Neoplasm Metastasis
Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
Neoplasm Metastasis
Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression.
Neoplasm Metastasis
microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells.
Neoplasm Metastasis
Microsphere-Based Nanoindentation for the Monitoring of Cellular Cortical Stiffness Regulated by MT1-MMP.
Neoplasm Metastasis
Miniaturized antibodies for imaging membrane type-1 matrix metalloproteinase in cancers.
Neoplasm Metastasis
miR-181 suppresses metastasis via MMP-14.
Neoplasm Metastasis
miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14.
Neoplasm Metastasis
miRNA-337-3p inhibits gastric cancer progression through repressing myeloid zinc finger 1-facilitated expression of matrix metalloproteinase 14.
Neoplasm Metastasis
MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.
Neoplasm Metastasis
MMP-14 can serve as a prognostic marker in patients with supraglottic cancer.
Neoplasm Metastasis
MMP1 expression is activated by Slug and enhances multi-drug resistance (MDR) in breast cancer.
Neoplasm Metastasis
Moesin regulates the motility of oral cancer cells via MT1-MMP and E-cadherin/p120-catenin adhesion complex.
Neoplasm Metastasis
Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.
Neoplasm Metastasis
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Neoplasm Metastasis
MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management.
Neoplasm Metastasis
MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis.
Neoplasm Metastasis
MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease.
Neoplasm Metastasis
MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1.
Neoplasm Metastasis
MT1-MMP: Endosomal delivery drives breast cancer metastasis.
Neoplasm Metastasis
Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts.
Neoplasm Metastasis
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Neoplasm Metastasis
New biochemical insight of conserved water molecules at catalytic and structural Zn(2+) ions in human matrix metalloproteinase-I: a study by MD-simulation.
Neoplasm Metastasis
NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP.
Neoplasm Metastasis
O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).
Neoplasm Metastasis
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
Neoplasm Metastasis
Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
Neoplasm Metastasis
Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells.
Neoplasm Metastasis
Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src.
Neoplasm Metastasis
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
Neoplasm Metastasis
Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1.
Neoplasm Metastasis
PLD and PA Take MT1-MMP for a Metastatic Ride.
Neoplasm Metastasis
Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
Neoplasm Metastasis
Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
Neoplasm Metastasis
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Neoplasm Metastasis
Prognostic Significance of Matrix Metalloproteinase 14 in Patients with Cancer: a Systematic Review and Meta-Analysis.
Neoplasm Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Neoplasm Metastasis
Prophylactical Low Dose Whole-Liver Irradiation Inhibited Colorectal Liver Metastasis by Regulating Hepatic Niche in Mice.
Neoplasm Metastasis
Prostate Cancer-Associated Membrane Type 1-Matrix Metalloproteinase. A Pivotal Role in Bone Response and Intraosseous Tumor Growth.
Neoplasm Metastasis
Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.
Neoplasm Metastasis
Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model.
Neoplasm Metastasis
Radioimmunodetection of membrane type-1 matrix metalloproteinase relevant to tumor malignancy with a pre-targeting method.
Neoplasm Metastasis
Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer.
Neoplasm Metastasis
Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
Neoplasm Metastasis
RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.
Neoplasm Metastasis
RNA interference screening identifies clathrin-B and cofilin-1 as mediators of MT1-MMP in endometrial cancer.
Neoplasm Metastasis
Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.
Neoplasm Metastasis
Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and metastasis.
Neoplasm Metastasis
Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis and tumor growth in ovarian cancer.
Neoplasm Metastasis
Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.
Neoplasm Metastasis
Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer.
Neoplasm Metastasis
Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.
Neoplasm Metastasis
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer.
Neoplasm Metastasis
SLC39A6 Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-kinase Signaling, and Upregulating Genes That Regulate Metastasis.
Neoplasm Metastasis
Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma.
Neoplasm Metastasis
SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis.
Neoplasm Metastasis
The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs.
Neoplasm Metastasis
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Neoplasm Metastasis
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression.
Neoplasm Metastasis
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
Neoplasm Metastasis
The membrane tethered matrix metalloproteinase MT1-MMP at the forefront of melanoma cell invasion and metastasis.
Neoplasm Metastasis
The polymorphism MMP1 -1607 (1G>2G) is associated with a significantly increased risk of cancers from a meta-analysis.
Neoplasm Metastasis
The protein kinase C inhibitor, H7, inhibits tumor cell invasion and metastasis in mouse melanoma via suppression of ERK1/2.
Neoplasm Metastasis
The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma.
Neoplasm Metastasis
The role of MMP-14 in ovarian cancer: a systematic review.
Neoplasm Metastasis
The role of stromal cells in the expression of interstitial collagenase (matrix metalloproteinase-1) in the invasion of gastric cancer.
Neoplasm Metastasis
The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways.
Neoplasm Metastasis
The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination.
Neoplasm Metastasis
Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
Neoplasm Metastasis
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.
Neoplasm Metastasis
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Neoplasm Metastasis
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Neoplasm Metastasis
Two-step sandwich enzyme immunoassay using monoclonal antibodies for detection of soluble and membrane-associated human membrane type 1-matrix metalloproteinase.
Neoplasm Metastasis
Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination.
Neoplasm Metastasis
Upregulation of SPOCK2 inhibits the invasion and migration of prostate cancer cells by regulating the MT1-MMP/MMP2 pathway.
Neoplasm Metastasis
YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis.
Neoplasm Metastasis
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
Neoplasm Metastasis
[Expression levels of MMP-14, ING4 and HIF-1? in 60 patients with oral squamous cell carcinoma and their clinical significance].
Neoplasm Metastasis
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Neoplasm Metastasis
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
Neoplasm Metastasis
[Interstitial collagenase and their endogenous regulators in squamous cell cervical carcinoma].
Neoplasm Metastasis
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Neoplasm Metastasis
[MiR-373-3p Promotes Invasion and Metastasis of Lung Adenocarcinoma Cells].
Neoplasm Metastasis
[Role of CD44 and MT1-MMP in colorectal cancer invasion and metastasis]
Neoplasm Metastasis
[Significance of membrane type-1 matrix metalloproteinase expression in breast cancer]
Neoplasm Metastasis
[The role of matrixmetalloproteinases in the tumor growth and metastasis].
Neoplasm Micrometastasis
Molecular markers of micrometastasis in oral cavity carcinomas.
Neoplasms
1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
Neoplasms
7,8-Dihydroxyflavone attenuates TNF-?-induced skin aging in Hs68 human dermal fibroblast cells via down-regulation of the MAPKs/Akt signaling pathways.
Neoplasms
?1 integrin-mediated signaling regulates MT1-MMP phosphorylation to promote tumor cell invasion.
Neoplasms
A hepatic invasive human colorectal xenograft model.
Neoplasms
A heterogeneous in vitro three dimensional model of tumour-stroma interactions regulating sprouting angiogenesis.
Neoplasms
A high throughput fluorogenic substrate for interstitial collagenase (MMP-1) and gelatinase (MMP-9).
Neoplasms
A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases.
Neoplasms
A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear.
Neoplasms
A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity.
Neoplasms
A new method for evaluation of urinary autocrine motility factor and tumor cell collagenase stimulating factor as markers for urinary tract cancers.
Neoplasms
A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagen.
Neoplasms
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Neoplasms
A partial catalog of proteins secreted by epidermal keratinocytes in culture.
Neoplasms
A role for MT1-MMP as a cell death sensor/effector through the regulation of endoplasmic reticulum stress in U87 glioblastoma cells.
Neoplasms
Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation.
Neoplasms
ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.
Neoplasms
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Neoplasms
Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton.
Neoplasms
Activatable and Cell-Penetrable Multiplex FRET Nanosensor for Profiling MT1-MMP Activity in Single Cancer Cells.
Neoplasms
Activated EphA2 Processing by MT1-MMP Is Involved in Malignant Transformation of Ovarian Tumours In Vivo.
Neoplasms
Activation of Epidermal Growth Factor Receptor/p38/Hypoxia-inducible Factor-1? Is Pivotal for Angiogenesis and Tumorigenesis of Malignantly Transformed Cells Induced by Hexavalent Chromium.
Neoplasms
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2.
Neoplasms
Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact Co-cultures.
Neoplasms
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasms
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Neoplasms
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Neoplasms
Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking.
Neoplasms
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Neoplasms
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth.
Neoplasms
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Neoplasms
Adverse drug reaction prediction using scores produced by large-scale drug-protein target docking on high-performance computing machines.
Neoplasms
Alpha V integrin prolongs collagenase production through Jun activation binding protein 1.
Neoplasms
Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors.
Neoplasms
An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase.
Neoplasms
An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy.
Neoplasms
Analysis for the major contributor of collagenase to the primary cleavage of type II collagens in cartilage degradation.
Neoplasms
Analysis of MT1-MMP and MMP2 expression in human gastric cancers.
Neoplasms
Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase.
Neoplasms
Antiprotease therapy in cancer: hot or not?
Neoplasms
Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase.
Neoplasms
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.
Neoplasms
Assessing matrix metalloproteinase expression and activity in hepatocellular carcinomas.
Neoplasms
Assignments, secondary structure and dynamics of the inhibitor-free catalytic fragment of human fibroblast collagenase.
Neoplasms
Association between matrix metalloproteinase 1 -1607 1G>2G polymorphism and cancer risk: a meta-analysis including 19706 subjects.
Neoplasms
Association of BCSC-1 and MMP-14 with human breast cancer.
Neoplasms
ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion.
Neoplasms
Atypical localization of membrane type 1-matrix metalloproteinase in the nucleus is associated with aggressive features of hepatocellular carcinoma.
Neoplasms
Autocrine regulation of collagenase gene expression by TNF-alpha in U937 cells.
Neoplasms
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Neoplasms
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide.
Neoplasms
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas.
Neoplasms
Bicyclic Peptides as a New Modality for Imaging and Targeting of Proteins Overexpressed by Tumors.
Neoplasms
Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells.
Neoplasms
Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression.
Neoplasms
Biological significance of interstitial collagenase in DMBA-induced mammary tumors of the rat.
Neoplasms
BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity.
Neoplasms
c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos.
Neoplasms
Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.
Neoplasms
Carcinoma of the parotid gland: developing prognostic indices.
Neoplasms
Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.
Neoplasms
CDCP1 regulates the function of MT1-MMP and invadopodia-mediated invasion of cancer cells.
Neoplasms
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Neoplasms
Cell surface activation of progelatinase A (proMMP-2) and cell migration.
Neoplasms
Cell type specific interleukin-6 induced responses in tumor keratinocytes and stromal fibroblasts are essential for invasive growth.
Neoplasms
Cell-cell contact activation of fibroblasts increases the expression of matrix metalloproteinases.
Neoplasms
Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis.
Neoplasms
Cellular membrane type-1 matrix metalloproteinase (MT1-MMP) cleaves C3b, an essential component of the complement system.
Neoplasms
Central and peripheral region tibial plateau chondrocytes respond differently to in vitro dynamic compression.
Neoplasms
Centrosomal pericentrin is a direct cleavage target of membrane type-1 matrix metalloproteinase in humans but not in mice: potential implications for tumorigenesis.
Neoplasms
Changes in the expression of matrix proteases and of the transcription factor c-Ets-1 during progression of precancerous bronchial lesions.
Neoplasms
Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas.
Neoplasms
Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis.
Neoplasms
Characterization of the procollagen IV cleavage products produced by a specific tumor collagenase.
Neoplasms
Chemical Tools for Selective Activity Profiling of Endogenously Expressed MMP-14 in Multicellular Models.
Neoplasms
Cleavage of growth differentiation factor 15 (GDF15) by membrane type 1-matrix metalloproteinase abrogates GDF15-mediated suppression of tumor cell growth.
Neoplasms
Cleavage of lumican by membrane-type matrix metalloproteinase-1 abrogates this proteoglycan-mediated suppression of tumor cell colony formation in soft agar.
Neoplasms
Cleavage of Type II and III collagens with mammalian collagenase: site of cleavage and primary structure at the NH2-terminal portion of the smaller fragment released from both collagens.
Neoplasms
Clinical and experimental role of ring finger protein 180 on lymph node metastasis and survival in gastric cancer.
Neoplasms
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Neoplasms
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Neoplasms
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Neoplasms
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Neoplasms
Cloning and characterization of human tumor cell interstitial collagenase.
Neoplasms
CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer.
Neoplasms
Co-localisation of intra-nuclear membrane type-1 matrix metalloproteinase and hypoxia inducible factor-2? in osteosarcoma and prostate carcinoma cells.
Neoplasms
Collagen regulation of let-7 in pancreatic cancer involves TGF-?1-mediated membrane type 1-matrix metalloproteinase expression.
Neoplasms
Collagenase activity in epidermoid carcinoma of the oral cavity and larynx.
Neoplasms
Collagenase activity in squamous cell carcinoma of the human parotid gland.
Neoplasms
Collagenase induction promotes mouse tumorigenesis by two independent pathways.
Neoplasms
Collagenase-1 injection improved tumor distribution and gene expression of cationic lipoplex.
Neoplasms
Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro.
Neoplasms
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Neoplasms
Collagenase-3 induction in rat lung fibroblasts requires the combined effects of tumor necrosis factor-alpha and 12-lipoxygenase metabolites: a model of macrophage-induced, fibroblast-driven extracellular matrix remodeling during inflammatory lung injury.
Neoplasms
Comparative analysis of matrix metalloproteinases by immunocytochemistry, immunohistochemistry and zymography in human primary brain tumours.
Neoplasms
Comparative Analysis of Tear Proteins in Keratoconic Scleral Lens Wearers with Variation in Limbal Clearance.
Neoplasms
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Neoplasms
Comparative gene expression profiling of normal and degenerative discs: analysis of a rabbit annular laceration model.
Neoplasms
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.
Neoplasms
Complete restoration of cell surface activity of transmembrane-truncated MT1-MMP by a glycosylphosphatidylinositol anchor. Implications for MT1-MMP-mediated prommp2 activation and collagenolysis in three-dimensions.
Neoplasms
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma.
Neoplasms
Concanavalin-A triggers inflammatory response through JAK/STAT3 signalling and modulates MT1-MMP regulation of COX-2 in mesenchymal stromal cells.
Neoplasms
Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells.
Neoplasms
Conjunctival expression of matrix metalloproteinase and pro-inflammatory cytokine genes following trichiasis surgery.
Neoplasms
Construction of antisense MT1-MMP vector and its inhibitory effects on invasion of human ovarian cancer cells.
Neoplasms
Conversion of stationary to invasive tumor initiating cells (TICs): role of hypoxia in membrane type 1-matrix metalloproteinase (MT1-MMP) trafficking.
Neoplasms
Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14.
Neoplasms
Coordinate action of membrane-type matrix metalloproteinase -1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion.
Neoplasms
Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function.
Neoplasms
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Neoplasms
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment.
Neoplasms
Critical role of transient activity of MT1-MMP for ECM degradation in invadopodia.
Neoplasms
Cyclophilin C-associated protein is a mediator for fibronectin fragment-induced matrix metalloproteinase-13 expression.
Neoplasms
Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.
Neoplasms
DCLK1 Plays a Metastatic-Promoting Role in Human Breast Cancer Cells.
Neoplasms
Decrease in LDL receptor-related protein expression and function correlates with advanced stages of Wilms tumors.
Neoplasms
Decreased MT1-MMP in gastric cancer suppressed cell migration and invasion via regulating MMPs and EMT.
Neoplasms
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Neoplasms
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).
Neoplasms
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Neoplasms
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Neoplasms
Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses.
Neoplasms
Detection of the Heterogeneous O-Glycosylation Profile of MT1-MMP Expressed in Cancer Cells by a Simple MALDI-MS Method.
Neoplasms
Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases.
Neoplasms
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.
Neoplasms
Development of membrane type-1 matrix metalloproteinase-specific activatable fluorescent probe for malignant tumor detection.
Neoplasms
Development of PEGylated peptide probes conjugated with (18)F-labeled BODIPY for PET/optical imaging of MT1-MMP activity.
Neoplasms
Differential effect of the expression of TGF-? pathway inhibitors, Smad-7 and Ski, on invasive breast carcinomas: relation to biologic behavior.
Neoplasms
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Neoplasms
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasms
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Neoplasms
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
Neoplasms
Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors.
Neoplasms
Differential regulation of matrix metalloproteinases in human cancer cells by exogenous factors.
Neoplasms
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.
Neoplasms
Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes.
Neoplasms
Differentiated expression of membrane type metalloproteinases (MMP-14, MMP-15) and pro-MMP2 in laryngeal squamous cell carcinoma. A novel mechanism.
Neoplasms
Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours.
Neoplasms
Direct production of functional matrix metalloproteinase--14 without refolding or activation and its application for in vitro inhibition assays.
Neoplasms
Directed Evolution of Protease Beacons that Enable Sensitive Detection of Endogenous MT1-MMP Activity in Tumor Cell Lines.
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Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.
Neoplasms
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Neoplasms
Down-Regulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion.
Neoplasms
Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells.
Neoplasms
Downregulation of reversion-inducing cysteine-rich protein with Kazal motifs in malignant melanoma: inverse correlation with membrane-type 1-matrix metalloproteinase and tissue inhibitor of metalloproteinase 2.
Neoplasms
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Neoplasms
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Neoplasms
Dual functions of ARP101 in targeting membrane type-1 matrix metalloproteinase: Impact on U87 glioblastoma cell invasion and autophagy signaling.
Neoplasms
Dual-functions of miR-373 and miR-520c by differently regulating the activities of MMP2 and MMP9.
Neoplasms
Early combined treatment with carboplatin and the MMP inhibitor, prinomastat, prolongs survival and reduces systemic metastasis in an aggressive orthotopic lung cancer model.
Neoplasms
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
Neoplasms
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Neoplasms
Effect of the different phosphorylated Smad2 protein localizations on the invasive breast carcinoma phenotype.
Neoplasms
Effects of flexibility of the ?2 chain of type I collagen on collagenase cleavage.
Neoplasms
Effects of miR-7 on Hcy-induced rat cerebral arterial vascular smooth muscle cell proliferation, migration and inflammatory factor expression by targeting MMP-14 to regulate TLR4/NF-?B signaling pathway.
Neoplasms
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Neoplasms
Elastin peptides activate extracellular signal-regulated kinase 1/2 via a Ras-independent mechanism requiring both p110gamma/Raf-1 and protein kinase A/B-Raf signaling in human skin fibroblasts.
Neoplasms
Elastokine-mediated up-regulation of MT1-MMP is triggered by nitric oxide in endothelial cells.
Neoplasms
Elevated expression of membrane type 1 metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system.
Neoplasms
Elevated expression of membrane-type 1 and 3 matrix metalloproteinases in rat vascular smooth muscle cells activated by arterial injury.
Neoplasms
Elevated furin expression in aggressive human head and neck tumors and tumor cell lines.
Neoplasms
ELK3 Expression Correlates With Cell Migration, Invasion, and Membrane Type 1-Matrix Metalloproteinase Expression in MDA-MB-231 Breast Cancer Cells.
Neoplasms
Emerging concepts in the regulation of membrane-type 1 matrix metalloproteinase activity.
Neoplasms
EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface.
Neoplasms
EMMPRIN expression in oral SCC is regulated by FYN kinase.
Neoplasms
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Neoplasms
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
Neoplasms
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Neoplasms
Enhanced membrane-type 1 matrix metalloproteinase expression by hyaluronan oligosaccharides in breast cancer cells facilitates CD44 cleavage and tumor cell migration.
Neoplasms
Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38.
Neoplasms
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Neoplasms
EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.
Neoplasms
EphA2 overexpression is associated with angiogenesis in ovarian cancer.
Neoplasms
Epigallocatechin gallate targeting of membrane type 1 matrix metalloproteinase-mediated Src and Janus kinase/signal transducers and activators of transcription 3 signaling inhibits transcription of colony-stimulating factors 2 and 3 in mesenchymal stromal cells.
Neoplasms
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Neoplasms
Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.
Neoplasms
Equine sarcoid fibroblasts over-express matrix metalloproteinases and are invasive.
Neoplasms
Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies.
Neoplasms
Evaluation of CD44 and TGF-B Expression in Oral Carcinogenesis.
Neoplasms
Evaluation of stromal metalloproteinases and vascular endothelial growth factors in a spontaneous metastasis model.
Neoplasms
Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.
Neoplasms
Examination of recombinant truncated mature human fibroblast collagenase by mass spectrometry: identification of differences with the published sequence and determination of stable isotope incorporation.
Neoplasms
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Neoplasms
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Neoplasms
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Neoplasms
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Neoplasms
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas.
Neoplasms
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Neoplasms
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Neoplasms
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Neoplasms
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Neoplasms
Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells.
Neoplasms
Expression of extracellular matrix molecules in brain metastasis.
Neoplasms
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo.
Neoplasms
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Neoplasms
Expression of matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and MT1-MMP in skin tumors of human papillomavirus type 8 transgenic mice.
Neoplasms
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Neoplasms
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Neoplasms
Expression of matrix metalloproteinase-2 in serous borderline ovarian tumors is associated with noninvasive implant formation.
Neoplasms
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: quantificative and morphological analyses.
Neoplasms
Expression of matrix metalloproteinases and their specific inhibitors in normal and different human thyroid tumor cell lines.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in reactive and neoplastic lymphoid cells.
Neoplasms
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Neoplasms
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase in medullary thyroid carcinoma: Prognostic implications.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Neoplasms
Expression of membrane type 1-matrix metalloproteinase in laryngeal carcinoma.
Neoplasms
Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells.
Neoplasms
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) mRNA in trophoblast and endometrial epithelial cell populations of the synepitheliochorial placenta of goats (Capra hircus).
Neoplasms
Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage.
Neoplasms
Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions.
Neoplasms
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.
Neoplasms
Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas.
Neoplasms
Expression of messenger RNAs for membrane-type 1, 2, and 3 matrix metalloproteinases in human renal cell carcinomas.
Neoplasms
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Neoplasms
Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas.
Neoplasms
Expression of metastasis-associated mts1 gene is co-induced with membrane type-1 matrix metalloproteinase (MT1-MMP) during oncogenic transformation and tubular formation of Madin Darby canine kidney (MDCK) epithelial cells.
Neoplasms
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Neoplasms
Expression of MMP-7 and MT1-MMP in oral squamous cell carcinoma as predictive indicator for tumor invasion and prognosis.
Neoplasms
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Neoplasms
Expression of MMPs and TIMPs in human pterygia and cultured pterygium epithelial cells.
Neoplasms
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.
Neoplasms
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Neoplasms
Expression of proteolytic enzymes in head and neck cancer-associated fibroblasts.
Neoplasms
Expression of the reversion-inducing cysteine-rich protein with Kazal motifs and matrix metalloproteinase-14 in neuroblastoma and the role in tumour metastasis.
Neoplasms
Expression of the transcription factor c-Ets1 correlates with the occurrence of invasive processes during normal and pathological development.
Neoplasms
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Neoplasms
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Neoplasms
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Neoplasms
Expression of urokinase plasminogen activator and its receptor in advanced epithelial ovarian cancer patients.
Neoplasms
Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.
Neoplasms
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Neoplasms
Expressions of matrix metalloproteinases in early-stage oral squamous cell carcinoma as predictive indicators for tumor metastases and prognosis.
Neoplasms
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex.
Neoplasms
Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
Neoplasms
Fibroblast growth factor-1 transcriptionally induces membrane type-1 matrix metalloproteinase expression in prostate carcinoma cell line.
Neoplasms
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.
Neoplasms
Fli-1 Activation through Targeted Promoter Activity Regulation Using a Novel 3', 5'-diprenylated Chalcone Inhibits Growth and Metastasis of Prostate Cancer Cells.
Neoplasms
Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.
Neoplasms
Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.
Neoplasms
Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14.
Neoplasms
Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP.
Neoplasms
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Neoplasms
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Neoplasms
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Neoplasms
Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers.
Neoplasms
Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis.
Neoplasms
Genetically Encoded Fluorescent Biosensors for Live-Cell Imaging of MT1-MMP Protease Activity.
Neoplasms
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Neoplasms
Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase.
Neoplasms
Gold Nanoparticle-Based Fluorescent Contrast Agent with Enhanced Sensitivity.
Neoplasms
Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype.
Neoplasms
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion.
Neoplasms
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Neoplasms
Heparin and heparan sulfate binding sites on B-16 melanoma cells.
Neoplasms
Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases.
Neoplasms
Hepatocyte nuclear factor 4 alpha promotes the invasion, metastasis and angiogenesis of neuroblastoma cells via targeting matrix metalloproteinase 14.
Neoplasms
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
Neoplasms
High MMP-1 mRNA expression is a risk factor for disease-free and overall survivals in patients with invasive breast carcinoma.
Neoplasms
High serum MMP-14 predicts worse survival in gastric cancer.
Neoplasms
High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells.
Neoplasms
High-affinity peptide against MT1-MMP for in vivo tumor imaging.
Neoplasms
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
Neoplasms
Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid.
Neoplasms
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Neoplasms
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Neoplasms
Human liver fibroblast capacity for synthesizing interstitial collagenase in vitro.
Neoplasms
Human Plasma Levels of Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, and Tissue Inhibitor of Matrix Metalloproteinase 1 and Their Applicability as Tumor Markers in Diagnoses of Cervical Cancer Based on ROC Analysis.
Neoplasms
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Neoplasms
Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy.
Neoplasms
Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.
Neoplasms
Identification of activated matrix metalloproteinase-2 (MMP-2) as the main gelatinolytic enzyme in malignant melanoma by in situ zymography.
Neoplasms
Identification of cis-acting promoter elements that support expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) in v-src transformed Madin-Darby canine kidney cells.
Neoplasms
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma.
Neoplasms
Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression.
Neoplasms
Identification of Proteolytic Cleavage Sites of EphA2 by Membrane Type 1 Matrix Metalloproteinase on the Surface of Cancer Cells.
Neoplasms
Identification of substrate sequences for membrane type-1 matrix metalloproteinase using bacteriophage peptide display library.
Neoplasms
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Neoplasms
Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma.
Neoplasms
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Neoplasms
Immunohistochemical detection of MT1-MMP, RECK, and EMMPRIN in ameloblastic tumors.
Neoplasms
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Neoplasms
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Neoplasms
Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.
Neoplasms
In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells.
Neoplasms
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Neoplasms
In vivo optical imaging of membrane-type matrix metalloproteinase (MT-MMP) activity.
Neoplasms
In vivo sensing of proteolytic activity with an NSET-based NIR fluorogenic nanosensor.
Neoplasms
Increased Aggressiveness of Human Prostate PC-3 Tumor Cells Expressing Cell Surface Localized Membrane Type-1 Matrix Metalloproteinase (MT1-MMP).
Neoplasms
Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas.
Neoplasms
Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness.
Neoplasms
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Neoplasms
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Neoplasms
Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.
Neoplasms
Increased expression of membrane-type matrix metalloproteinase-1 is correlated with poor prognosis in patients with osteosarcoma.
Neoplasms
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Neoplasms
Increased immunoreactivity of MT1-MMP and beta-catenin in high risk basal cell carcinoma.
Neoplasms
Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.
Neoplasms
Increases of stromelysin messenger-RNA expression in ras-transformed ref cells in-vivo.
Neoplasms
Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1.
Neoplasms
Induction of macrophage matrix metalloproteinase biosynthesis by surfactant protein D.
Neoplasms
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Neoplasms
Induction of Smad1 by MT1-MMP contributes to tumor growth.
Neoplasms
Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase.
Neoplasms
Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Neoplasms
Inhibition of matrix metalloproteinase-14 (MMP-14)-mediated cancer cell migration.
Neoplasms
Inhibition of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation blocks tumor progression in mice.
Neoplasms
Inhibition of MT1-MMP activity using functional antibody fragments selected against its hemopexin domain.
Neoplasms
Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor.
Neoplasms
Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas.
Neoplasms
Insufficient CD100 shedding contributes to suppression of CD8+ T cell activity in non-small cell lung cancer.
Neoplasms
Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.
Neoplasms
Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
Neoplasms
Interaction of MT1-MMP and laminin-5gamma2 chain correlates with metastasis and invasiveness in human esophageal squamous cell carcinoma.
Neoplasms
Interaction of Munc18c and Syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumour cells.
Neoplasms
Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.
Neoplasms
Interleukin-1 beta- and tumor necrosis factor-alpha-independent monocyte stimulation of fibroblast collagenase activity.
Neoplasms
Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression.
Neoplasms
Interplay of transcription factors STAT3, STAT1 and AP-1 mediates activity of the matrix metallo-proteinase-1 promoter in colorectal carcinoma cells.
Neoplasms
Interstitial collagenase and the ED-B oncofetal domain of fibronectin are markers of angiogenesis in human skin tumors.
Neoplasms
Interstitial collagenase gene expression in colonic neoplasia.
Neoplasms
Interstitial collagenases as markers of tumor progression.
Neoplasms
Intradomain cleavage of the inhibitory prodomain is essential to the pro-tumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo.
Neoplasms
Intrahepatic metastasis by orthotopic implantation of a fragment of murine hepatoma and its related molecules.
Neoplasms
Intratumoral concentrations of tissue inhibitor of matrix metalloproteinase 1 in patients with gastric carcinoma a new biomartker for invasion and its impact on survival.
Neoplasms
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.
Neoplasms
Invasion by activated macrophages requires delivery of nascent membrane-type-1 matrix metalloproteinase through late endosomes/lysosomes to the cell surface.
Neoplasms
Invasion of connective tissue by human carcinoma cell lines: requirement for urokinase, urokinase receptor, and interstitial collagenase.
Neoplasms
Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex.
Neoplasms
Invasiveness of hepatocellular carcinoma cell lines: contribution of membrane-type 1 matrix metalloproteinase.
Neoplasms
Involvement of lipid peroxidation and organic peroxides in UVA-induced matrix metalloproteinase-1 expression.
Neoplasms
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Neoplasms
Isolation and characterization of novel RECK tumor suppressor gene splice variants.
Neoplasms
iTRAQ-Based Membrane Proteomics Reveals Plasma Membrane Proteins Change During HepaRG Cell Differentiation.
Neoplasms
Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression.
Neoplasms
Lack of Association between Membrane-Type 1 Matrix Metalloproteinase Expression and Clinically Relevant Molecular or Morphologic Tumor Characteristics at the Leading Edge of Invasive Colorectal Carcinoma.
Neoplasms
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.
Neoplasms
Letter regarding "MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies" by Wu KP et al.
Neoplasms
LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells.
Neoplasms
LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.
Neoplasms
Local activity of matrix metalloproteinases in a case of botryoid sarcoma.
Neoplasms
Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains.
Neoplasms
Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds.
Neoplasms
Localized surface plasmon resonance based nanobiosensor for biomarker detection of invasive cancer cells.
Neoplasms
Low collagenase-1 (MMP-1) and MT1-MMP expression levels are favourable survival markers in advanced colorectal carcinoma.
Neoplasms
Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.
Neoplasms
Lumican: a new inhibitor of matrix metalloproteinase-14 activity.
Neoplasms
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Neoplasms
Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.
Neoplasms
Mathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases.
Neoplasms
Matrix influence on the tumor cell stimulation of fibroblast collagenase production.
Neoplasms
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia.
Neoplasms
Matrix metalloproteinase 1 and circulating tumor cells in early breast cancer.
Neoplasms
Matrix Metalloproteinase 1 promotes tumor formation and lung metastasis in an intratibial injection osteosarcoma mouse model.
Neoplasms
Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer.
Neoplasms
Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database.
Neoplasms
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Neoplasms
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Neoplasms
Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material.
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Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
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Matrix metalloproteinase production by cultured human endometrial stromal cells: identification of interstitial collagenase, gelatinase-A, gelatinase-B, and stromelysin-1 and their differential regulation by interleukin-1 alpha and tumor necrosis factor-alpha.
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Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk.
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Matrix metalloproteinase-14 (MMP-14) downregulation inhibits esophageal squamous cell carcinoma cell migration, invasion, and proliferation.
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Matrix Metalloproteinase-14 (MT1-MMP)-Mediated Endoglin Shedding Inhibits Tumor Angiogenesis.
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Matrix Metalloproteinase-14 Is a Negative Prognostic Marker for Patients with Gastric Cancer.
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Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
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Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.
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Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis.
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Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
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Matrix metalloproteinases play an active role in Wnt1-induced mammary tumorigenesis.
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Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.
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Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.
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Matrix-directed regulation of pericellular proteolysis and tumor progression.
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Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques.
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Matrix-metalloproteinases in bronchopulmonary carcinomas.
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mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization.
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Mechanism of metastasis by membrane type 1-matrix metalloproteinase in hepatocellular carcinoma.
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Mechanistic insights into targeting T cell membrane proteinase to promote islet beta-cell rejuvenation in type 1 diabetes.
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Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.
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Membrane type 1 matrix metalloproteinase detection in tumors, using the iodinated endogenous [123I]-tissue inhibitor 2 of metalloproteinases as imaging agent.
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Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules.
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Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators.
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Membrane type 1 matrix metalloproteinase induces epithelial-to-mesenchymal transition in prostate cancer.
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Membrane type 1 matrix metalloproteinase regulates anaplastic thyroid carcinoma cell growth and invasion into the collagen matrix.
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Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
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Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation.
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Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor.
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Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses.
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Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis.
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Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-?-induced procoagulant activity and apoptosis in endothelial cells.
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Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix.
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Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface.
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Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
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Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability.
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Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells.
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Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-?.
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Membrane type-1 matrix metalloproteinase functions as a proprotein self-convertase. Expression of the latent zymogen in Pichia pastoris, autolytic activation, and the peptide sequence of the cleavage forms.
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Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growth.
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Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins.
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Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors.
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Membrane-type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at K581 increases cellular invasion through type-I collagen.
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Membrane-type 1 matrix metalloproteinase and cell migration.
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Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.
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Membrane-Type 1 Matrix Metalloproteinase Downregulates Fibroblast Growth Factor-2 Binding to the Cell Surface and Intracellular Signaling.
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Membrane-type 1 matrix metalloproteinase enhances lymph node metastasis of gastric cancer.
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Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells.
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Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion.
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Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
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Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases.
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Membrane-type I matrix metalloproteinase-dependent ectodomain shedding of mucin16/ CA-125 on ovarian cancer cells modulates adhesion and invasion of peritoneal mesothelium.
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Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.
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Membrane-type matrix metalloproteinase-1 (MT1-MMP) is down-regulated in estrogen-deficient rat osteoblast in vivo.
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Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas.
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Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
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Membrane-type metalloproteinases in tumor invasion.
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Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
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Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion.
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Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
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Metalloproteinase binding proteins: WO2009097397.
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Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
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Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
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Methylseleninic acid inhibits PMA-stimulated pro-MMP-2 activation mediated by MT1-MMP expression and further tumor invasion through suppression of NF-kappaB activation.
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MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10.
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microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells.
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Microsphere-Based Nanoindentation for the Monitoring of Cellular Cortical Stiffness Regulated by MT1-MMP.
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Miniaturized antibodies for imaging membrane type-1 matrix metalloproteinase in cancers.
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Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression.
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Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin ?5?1 and tumour growth.
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miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.
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miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14.
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miR?146a?5p targets TCSF and influences cell growth and apoptosis to repress NSCLC progression.
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miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14.
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miRNA-584-5p exerts tumor suppressive functions in human neuroblastoma through repressing transcription of matrix metalloproteinase 14.
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MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression.
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MMP-14 (MT1-MMP) Is a Biomarker of Surgical Outcome and a Potential Mediator of Hearing Loss in Patients With Vestibular Schwannomas.
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MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
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MMP-14 can serve as a prognostic marker in patients with supraglottic cancer.
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MMP-14 Triggered Fluorescence Contrast Agent.
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MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
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MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging.
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Mmp1a and Mmp1b are not functional orthologs to human MMP1 in cigarette smoke induced lung disease.
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Modulation of peritumoral fibroblasts with a membrane-tethered tissue inhibitor of metalloproteinase (TIMP) for the elimination of cancer cells.
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Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices.
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Molecular markers of micrometastasis in oral cavity carcinomas.
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Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.
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Monitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression.
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Monoclonal antibody preparation and purification of a tumor cell collagenase-stimulatory factor.
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Morbillivirus infection of the mouse central nervous system induces region-specific upregulation of MMPs and TIMPs correlated to inflammatory cytokine expression.
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mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
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mRNA levels of membrane-type 1 matrix metalloproteinase (MT1-MMP), MMP-2, and MMP-9 and of their inhibitors TIMP-2 and TIMP-3 in normal thyrocytes and thyroid carcinoma cell lines.
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MT-MMPS as Regulators of Vessel Stability Associated with Angiogenesis.
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MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging.
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MT1-MMP Activation of TGF-? Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer.
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MT1-MMP and integrins: Hand-to-hand in cell communication.
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MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
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MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
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MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization.
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MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management.
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MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
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MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.
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MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion.
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MT1-MMP expression in first-trimester placental tissue is upregulated in type 1 diabetes as a result of elevated insulin and tumor necrosis factor-alpha levels.
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MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells.
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MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
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MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies.
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MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease.
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MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1.
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MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway.
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MT1-MMP promotes cell growth and ERK activation through c-Src and paxillin in three-dimensional collagen matrix.
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MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis.
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MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins.
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MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy.
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MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7.
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MT1-mmp: a collagenase essential for tumor cell invasive growth.
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MT1-MMP: a potent modifier of pericellular microenvironment.
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MT1-MMP: Endosomal delivery drives breast cancer metastasis.
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MT1-MMP: universal or particular player in angiogenesis?
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mTOR Repression in Response to Amino Acid Starvation Promotes ECM Degradation Through MT1-MMP Endocytosis Arrest.
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N-Acetylglucosaminyltransferase V triggers overexpression of MT1-MMP and reinforces the invasive/metastatic potential of cancer cells.
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N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
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N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.
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Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision.
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New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
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New photodynamic molecular beacons (PMB) as potential cancer-targeted agents in PDT.
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NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway.
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Non-destructive and selective imaging of the functionally active, pro-invasive membrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells.
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Non-proteolytic, receptor/ligand interactions associate cellular membrane type-1 matrix metalloproteinase with the complement component C1q.
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Noncanonical Activation of Notch1 Protein by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Controls Melanoma Cell Proliferation.
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Noninvasive Bioluminescence Imaging of Matrix Metalloproteinase-14 Activity in Lung Cancer Using a Membrane-Bound Biosensor.
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Novel MT1-MMP small molecule inhibitors based on insights into hemopexin domain function in tumor growth.
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Nucleus-Invadopodia Duo During Cancer Invasion.
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O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).
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Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation.
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Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells.
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Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
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Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
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Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice.
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Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
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OXIDATIVE STRESS AND PROSTATE CANCER PROGRESSION ARE ELICITED BY MEMBRANE-TYPE 1 MATRIX METALLOPROTEINASE (MT1-MMP).
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p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
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p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer.
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Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion.
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Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1.
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PEA3 is necessary for optimal epidermal growth factor receptor-stimulated matrix metalloproteinase expression and invasion of ovarian tumor cells.
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Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP.
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Pharmacology of [3H]-pyrilamine binding and of the histamine-induced inositol phosphates generation, intracellular Ca2+ -mobilization and cytokine release from human corneal epithelial cells.
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Phase Differential Enhancement of FLIM to Distinguish FRET Components of a Biosensor for Monitoring Molecular Activity of Membrane Type 1 Matrix Metalloproteinase in Live Cells.
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Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
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Phosphoramidate-based peptidomimetic inhibitors of membrane type-1 matrix metalloproteinase.
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PLAU1 Facilitated Proliferation, Invasion, and Metastasis via Interaction With MMP1 in Head and Neck Squamous Carcinoma.
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Podoplanin promotes the invasion of oral squamous cell carcinoma in coordination with MT1-MMP and Rho GTPases.
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Polarized MT1-MMP-CD44 interaction and CD44 cleavage during cell retraction reveal an essential role for MT1-MMP in CD44-mediated invasion.
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Polyethylenimine-coated SPION exhibits potential intrinsic anti-metastatic properties inhibiting migration and invasion of pancreatic tumor cells.
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Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.
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Polymorphonuclear cells stimulate the migration and metastatic potential of rat sarcoma cells.
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Positive correlation between inhibitors of matrix metalloproteinase 1 and matrix metalloproteinases in malignant ovarian tumor tissues.
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Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
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Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
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Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells.
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Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
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Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
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Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
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Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
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Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells.
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Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
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Primary renal neuroblastoma with metastasis and matrix metalloproteinase-14 expression.
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Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.
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Profiling of differential gene expression in Wilms tumor by cDNA expression array.
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Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.
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Prognostic Influence of Tumor Stroma on Breast Cancer Subtypes.
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Prognostic Significance of Matrix Metalloproteinase 14 in Patients with Cancer: a Systematic Review and Meta-Analysis.
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Prognostic significance of matrix metalloproteinases type I expression and tumor front parameters in the presence of lymph node micrometastases in carcinoma of the larynx.
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Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
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Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
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Prostate Cancer-Associated Membrane Type 1-Matrix Metalloproteinase. A Pivotal Role in Bone Response and Intraosseous Tumor Growth.
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Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.
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Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited.
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Protective effect of MAAs extracted from Porphyra tenera against UV irradiation-induced photoaging in mouse skin.
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Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein.
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Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation.
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Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells.
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Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy.
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Proteolyzed matrix as a template for the regulation of tumor progression.
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Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion.
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Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts.
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Quantitative cell dispersion analysis: new test to measure tumor cell aggressiveness.
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Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells.
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Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
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Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model.
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Radioimmunodetection of membrane type-1 matrix metalloproteinase relevant to tumor malignancy with a pre-targeting method.
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Radioiodinated Peptidic Imaging Probes for in Vivo Detection of Membrane Type-1 Matrix Metalloproteinase in Cancers.
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Rat carcinoma cells in long-term, serum-free culture provide a continuing supply of collagenase.
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Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer.
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Red-shifted fluorescent proteins monitor enzymatic activity in live HT-1080 cells with fluorescence lifetime imaging microscopy (FLIM).
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Reduced expression of insulin-like growth factor-binding protein-3 (IGFBP-3) in Squamous cell carcinoma complicating recessive dystrophic epidermolysis bullosa.
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Regulation of gelatinases in human airway smooth muscle cells: mechanism of progelatinase A activation.
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Regulation of membrane-type 1 matrix metalloproteinase activity by vacuolar H+-ATPases.
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Regulation of MT1-MMP activity by ?-catenin in MDCK non-cancer and HT1080 cancer cells.
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Regulation of MT1-MMP Activity through Its Association with ERMs.
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Regulation of MT1-MMP and MMP-2 by the serpin PEDF: a promising new target for metastatic cancer.
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Relation of MT1-MMP gene expression to outcomes in colorectal cancer.
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Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
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RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.
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RNA interference screening identifies clathrin-B and cofilin-1 as mediators of MT1-MMP in endometrial cancer.
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Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
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Role of the matrix metalloproteinase and tissue inhibitors of metalloproteinase families in noninvasive and invasive tumors transplanted in mice with severe combined immunodeficiency.
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Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells.
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Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma.
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Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and metastasis.
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Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis.
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SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2.
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Screening, Identification, and Characterization of an Affinity Peptide Specific to MT1-MMP and Its Application in Tumor Imaging.
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SCUBE3 regulation of early lung cancer angiogenesis and metastatic progression.
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Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes.
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Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis and tumor growth in ovarian cancer.
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Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.
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Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
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Selective modulation of collagenase 1 gene expression by the chemotherapeutic agent doxorubicin.
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Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.
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Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2.
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Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer.
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Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.
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Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
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Significance of membrane type 1 matrix metalloproteinase expression in breast cancer.
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Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer.
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Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.
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Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer.
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Single-nucleotide polymorphisms and haplotypes of membrane type 1-matrix metalloproteinase in susceptibility and clinical significance of squamous cell neoplasia of uterine cervix in taiwan women.
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SLFN5 suppresses cancer cell migration and invasion by inhibiting MT1-MMP expression via AKT/GSK-3?/?-catenin pathway.
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Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?
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Soluble Lutheran/basal cell adhesion molecule is detectable in plasma of hepatocellular carcinoma patients and modulates cellular interaction with laminin-511 in vitro.
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Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells: down-regulation of matrix metalloproteinase-3/-9/-14 and CD44.
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SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
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Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and tumor cell migration.
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Stable expression of ?1-antitrypsin Portland in MDA-MB-231 cells increased MT1-MMP and MMP-9 levels, but reduced tumour progression.
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Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines.
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Strategies of chemoprevention based on antigenic and molecular markers of early and premalignant lesions of the bladder.
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Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.
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Stromal expression of c-Ets1 transcription factor correlates with tumor invasion.
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Stromelysin-3 induction and interstitial collagenase repression by retinoic acid. Therapeutical implication of receptor-selective retinoids dissociating transactivation and AP-1-mediated transrepression.
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Structural Studies of Matrix Metalloproteinase by X-Ray Diffraction.
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Suppressing TGF? Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer.
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Suppression of hepatic fat accumulation by highly purified eicosapentaenoic acid prevents the progression of d-galactosamine-induced hepatitis in mice fed with a high-fat/high-sucrose diet.
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Syndecan-1 and -4 differentially regulate oncogenic K-ras dependent cell invasion into collagen through ?2?1 integrin and MT1-MMP.
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Synergistic metalloproteinase-based remodeling of matrix by pancreatic tumor and stromal cells.
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Synovial fluid levels of TWEAK and matrix metalloproteinase 1 in patients with osteoarthritis, and associations with disease severity.
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Synthesis of interleukin 1beta, tumor necrosis factor-alpha, and interstitial collagenase (MMP-1) is eicosanoid dependent in human osteoarthritis synovial membrane explants: interactions with antiinflammatory cytokines.
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Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors.
Neoplasms
Tagitinin F has anti-inflammatory, anti-nociceptive and anti-matrix metalloproteinase properties: An in silico, in vitro and in vivo study.
Neoplasms
Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer.
Neoplasms
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
Neoplasms
Targeting Extracellular Matrix Remodeling restores BRAF Inhibitor Sensitivity in BRAFi Resistant Melanoma.
Neoplasms
Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models.
Neoplasms
Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.
Neoplasms
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
Neoplasms
Targeting the warburg effect, which arises in tumor cells expressing membrane-type-1 matrix metalloproteinase.
Neoplasms
Teneligliptin inhibits IL-1?-induced degradation of extracellular matrix in human chondrocytes.
Neoplasms
Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis.
Neoplasms
TGF-?1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells.
Neoplasms
TGF-?1 promotes linear invadosome formation in hepatocellular carcinoma cells, through DDR1 up-regulation and collagen I cross-linking.
Neoplasms
The activity of a designer tissue inhibitor of metalloproteinases (TIMP)-1 against native membrane type 1 matrix metalloproteinase (MT1-MMP) in a cell-based environment.
Neoplasms
The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs.
Neoplasms
The chondroprotective drugs, Arteparon and sodium pentosan polysulphate, increase collagenase activity and inhibit stromelysin activity in vitro.
Neoplasms
The clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer.
Neoplasms
The clinicopathological and prognostic significance of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-9 according to their localization in invasive breast carcinoma.
Neoplasms
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Neoplasms
The cytoplasmic tail peptide sequence of membrane type-1 matrix metalloproteinase (MT1-MMP) directly binds to gC1qR, a compartment-specific chaperone-like regulatory protein.
Neoplasms
The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.
Neoplasms
The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression.
Neoplasms
The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors.
Neoplasms
The Expanding Role of MT1-MMP in Cancer Progression.
Neoplasms
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Neoplasms
The expression of MMP-14 and microRNA-410 in FFPE tissues of human endometrial adenocarcinoma.
Neoplasms
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression.
Neoplasms
The HIV protease inhibitor indinavir down-regulates the expression of the pro-angiogenic MT1-MMP by human endothelial cells.
Neoplasms
The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells.
Neoplasms
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
Neoplasms
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.
Neoplasms
The Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity.
Neoplasms
The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.
Neoplasms
The polymorphism MMP1 -1607 (1G>2G) is associated with a significantly increased risk of cancers from a meta-analysis.
Neoplasms
The Precise Diagnosis of Cancer Invasion/Metastasis via 2D Laser Ablation Mass Mapping of Metalloproteinase in Primary Cancer Tissue.
Neoplasms
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
Neoplasms
The role of MMP-14 in ovarian cancer: a systematic review.
Neoplasms
The role of MT2-MMP in cancer progression.
Neoplasms
The role of stromal cells in the expression of interstitial collagenase (matrix metalloproteinase-1) in the invasion of gastric cancer.
Neoplasms
The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis.
Neoplasms
The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination.
Neoplasms
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
Neoplasms
Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells.
Neoplasms
Three-dimensional collagen I promotes gemcitabine resistance in pancreatic cancer through MT1-MMP-mediated expression of HMGA2.
Neoplasms
Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.
Neoplasms
TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.
Neoplasms
TIMP-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.
Neoplasms
TIMP-2 fusion protein with human serum albumin potentiates anti-angiogenesis-mediated inhibition of tumor growth by suppressing MMP-2 expression.
Neoplasms
TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis.
Neoplasms
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Neoplasms
Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
Neoplasms
Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.
Neoplasms
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
Neoplasms
Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes.
Neoplasms
Tissue inhibitor of metalloproteinases-1 (TIMP-1) RNA is expressed at elevated levels in malignant non-Hodgkin's lymphomas.
Neoplasms
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.
Neoplasms
Tissue microarrays of human tumor xenografts: characterization of proteins involved in migration and angiogenesis for applications in the development of targeted anticancer agents.
Neoplasms
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent.
Neoplasms
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.
Neoplasms
Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells.
Neoplasms
TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.
Neoplasms
Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness.
Neoplasms
Transforming growth factor-beta induces CD44 cleavage that promotes migration of MDA-MB-435s cells through the up-regulation of membrane type 1-matrix metalloproteinase.
Neoplasms
Transient collagen triple helix binding to a key metalloproteinase in invasion and development.
Neoplasms
Transient increase of intracellular cAMP by heat shock initiates the suppression of MT1-MMP production in tumor cells.
Neoplasms
Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves alphav integrins and the participation of MMP2.
Neoplasms
Treatment of rheumatoid synovitis with anti-reshaping human interleukin-6 receptor monoclonal antibody: use of rheumatoid arthritis tissue implants in the SCID mouse model.
Neoplasms
Tube travel: the role of proteases in individual and collective cancer cell invasion.
Neoplasms
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling.
Neoplasms
Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.
Neoplasms
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.
Neoplasms
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP.
Neoplasms
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase.
Neoplasms
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Neoplasms
Tumor collagenase stimulating factor (TCSF) and tumor autocrine motility factor (TAMF) in bladder cancer.
Neoplasms
Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.
Neoplasms
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Neoplasms
Tumor necrosis factor-alpha stimulates the biosynthesis of matrix metalloproteinases and plasminogen activator in cultured human chorionic cells.
Neoplasms
Tumor necrosis factor-alpha-stimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts.
Neoplasms
Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes.
Neoplasms
Tumor-derived death receptor 6 modulates dendritic cell development.
Neoplasms
Tumor-stroma interactions of metastatic prostate cancer cell lines: analyses using microarrays.
Neoplasms
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
Neoplasms
Tumour-targeting properties of antibodies specific to MMP-1A, MMP-2 and MMP-3.
Neoplasms
Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans: relationship to mediators of systemic and local inflammation.
Neoplasms
Twist is required for thrombin-induced tumor angiogenesis and growth.
Neoplasms
Two-step sandwich enzyme immunoassay using monoclonal antibodies for detection of soluble and membrane-associated human membrane type 1-matrix metalloproteinase.
Neoplasms
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Neoplasms
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Neoplasms
Up-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis.
Neoplasms
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
Neoplasms
Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: a major induction of stromal MMP-13.
Neoplasms
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Neoplasms
Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process.
Neoplasms
v-src activation of the collagenase-1 (matrix metalloproteinase-1) promoter through PEA3 and STAT: requirement of extracellular signal-regulated kinases and inhibition by retinoic acid receptors.
Neoplasms
Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
Neoplasms
Vinculin negatively regulates transcription of MT1-MMP through MEK/ERK pathway.
Neoplasms
Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging.
Neoplasms
When MT1-MMP meets ADAMs.
Neoplasms
[Changes of lymphatic vessel density in lung adenocarcinoma in situ, minimally invasive adenocarcinoma, and invasive adenocarcinoma and the regulatory factors].
Neoplasms
[Construction and expression of hTNF-alpha fusion protein mediated by MMP1].
Neoplasms
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
Neoplasms
[Correlation of membrane type I matrix metalloproteinase (MT1-MMP) expression with clinicomorphological features of tumor front in squamous cell carcinoma of the larynx]
Neoplasms
[Dectection and analysis of miRNA expression in breast cancer-associated fibroblasts].
Neoplasms
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
Neoplasms
[Effects of MT1-MMP on the in vitro invasiveness of breast cancer cells]
Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Neoplasms
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
Neoplasms
[Expression of MT1-MMP and its significance in rabbit VX2 tumor tissues after transarterial embolization with hydroxyapatite nanoparticles]
Neoplasms
[Expression pattern of membrane type-1 matrix metalloproteinase in primary breast carcinomas].
Neoplasms
[Impact of biological function on ovarian clear cell carcinoma ES2 cell line with ARID1A gene expression down-regulating in vitro].
Neoplasms
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
Neoplasms
[Interstitial collagenase and their endogenous regulators in squamous cell cervical carcinoma].
Neoplasms
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Neoplasms
[Matrix metalloproteinases and their endogenous regulators in squamous cervical carcinoma (review of the own data)].
Neoplasms
[Membrane type 1 matrix metalloproteinase (MT1-MMP) and the regulators of its activity as invasive factors in squamous cell cervical carcinomas.]
Neoplasms
[Morphological tumor front grading and matrix metalloproteinases type I expression as a prognostic parameter of the presence of lymph node micrometastases in laryngeal carcinoma]
Neoplasms
[MT1-MMP up-regulates VEGF expression in human breast carcinoma MCF-7 cells and induces tumor angiogenesis]
Neoplasms
[Progress on evaluation criterion of wound healing]
Neoplasms
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
Neoplasms
[Significance of membrane type-1 matrix metalloproteinase expression in breast cancer]
Neoplasms
[The expressions of TNF-alpha and MMP-9 in serum and MMP-1 mRNA in the bone tissue in chronic obstructive pulmonary disease patients of cold dryness syndrome in northwest China].
Neoplasms
[The role of matrixmetalloproteinases in the tumor growth and metastasis].
Neoplasms
[Tissue collagenase MMP-14 and endogenous regulators of its activity in the corpus uteri in squamous cell carcinoma of the cervix].
Neoplasms
[Virtual screening and molecular simulations of antisense peptides targeting MT1-MMP].
Neoplastic Cells, Circulating
Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas.
Neoplastic Cells, Circulating
Matrix metalloproteinase 1 and circulating tumor cells in early breast cancer.
Nephritis, Hereditary
Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).
Nephrosclerosis
Endothelial sirtuin 1 deficiency perpetrates nephrosclerosis through downregulation of matrix metalloproteinase-14: relevance to fibrosis of vascular senescence.
Neuralgia
Matrix Metalloproteinase-14 Both Sheds Cell Surface Neuronal Glial Antigen 2 (NG2) Proteoglycan on Macrophages and Governs the Response to Peripheral Nerve Injury.
Neuralgia
Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain.
Neurilemmoma
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
Neuroblastoma
Assessment of the MT1-MMP expression level of different cell lines by the naked eye.
Neuroblastoma
Expression of the reversion-inducing cysteine-rich protein with Kazal motifs and matrix metalloproteinase-14 in neuroblastoma and the role in tumour metastasis.
Neuroblastoma
Hepatocyte nuclear factor 4 alpha promotes the invasion, metastasis and angiogenesis of neuroblastoma cells via targeting matrix metalloproteinase 14.
Neuroblastoma
Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression.
Neuroblastoma
microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells.
Neuroblastoma
miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14.
Neuroblastoma
Two transcription factors, E1AF and N-myc, correlate with the invasiveness of neuroblastoma cell lines.
Neurodegenerative Diseases
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Neurodegenerative Diseases
MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy.
Neuroendocrine Tumors
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
Neurofibroma
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
Neurofibroma
Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine.
Neurofibromatosis 1
Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine.
Neuroma, Acoustic
MMP-14 (MT1-MMP) Is a Biomarker of Surgical Outcome and a Potential Mediator of Hearing Loss in Patients With Vestibular Schwannomas.
Nevus
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Nevus
Implication of MT1-MMP in the maturation steps of benign melanocytic nevi.
Nevus
MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1.
Nevus, Intradermal
Implication of MT1-MMP in the maturation steps of benign melanocytic nevi.
Nevus, Pigmented
Implication of MT1-MMP in the maturation steps of benign melanocytic nevi.
Nevus, Pigmented
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
Obesity
Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans.
Obstetric Labor, Premature
Changes in gene expression of cervical collagens, metalloproteinases, and tissue inhibitors of metalloproteinases after partial cervical excision-induced preterm labor in mice.
Obstetric Labor, Premature
Distinct molecular events suggest different pathways for preterm labor and premature rupture of membranes.
Odontogenic Cysts
Interleukin-1alpha enhances type I collagen-induced activation of matrix metalloproteinase-2 in odontogenic keratocyst fibroblasts.
Odontogenic Tumors
Immunohistochemical detection of MT1-MMP, RECK, and EMMPRIN in ameloblastic tumors.
Osteoarthritis
A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death.
Osteoarthritis
Analysis for the major contributor of collagenase to the primary cleavage of type II collagens in cartilage degradation.
Osteoarthritis
Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression.
Osteoarthritis
Cloning of collagenase 3 from the synovial membrane and its expression in rheumatoid arthritis and osteoarthritis.
Osteoarthritis
Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis.
Osteoarthritis
Effects of MMP-1 1G/2G polymorphism on osteoarthritis: A meta-analysis study.
Osteoarthritis
Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
Osteoarthritis
In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1beta synthesis.
Osteoarthritis
Induction of matrix metalloproteinase 1 gene expression is regulated by inflammation-responsive transcription factor SAF-1 in osteoarthritis.
Osteoarthritis
Role of eicosanoids in structural degradation in osteoarthritis.
Osteoarthritis
Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors.
Osteoarthritis
Synovial fluid levels of TWEAK and matrix metalloproteinase 1 in patients with osteoarthritis, and associations with disease severity.
Osteoarthritis
Synthesis of interleukin 1beta, tumor necrosis factor-alpha, and interstitial collagenase (MMP-1) is eicosanoid dependent in human osteoarthritis synovial membrane explants: interactions with antiinflammatory cytokines.
Osteoarthritis
Testican-1, an inhibitor of pro-MMP-2 activation, is expressed in cartilage.
Osteoarthritis
The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk.
Osteoarthritis
The effects of tenidap on canine experimental osteoarthritis: II. Study of the expression of collagenase-1 and interleukin 1beta by in situ hybridization.
Osteoarthritis
The involvement of matrix metalloproteinases and inflammation in lumbar disc herniation.
Osteoarthritis
Variation of Matrix Metalloproteinase 1 and 3 Haplotypes and Their Serum Levels in Patients with Rheumatoid Arthritis and Osteoarthritis.
Osteolysis
ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.
Osteolysis
Characterization of Normal Murine Carpal Bone Development Prompts Re-Evaluation of Pathologic Osteolysis as the Cause of Human Carpal-Tarsal Osteolysis Disorders.
Osteolysis
Genetic susceptibility to aseptic loosening following total hip arthroplasty: a systematic review.
Osteolysis
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Osteolysis
Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.
Osteonecrosis
MMP-14 single-nucleotide polymorphisms are related to steroid-induced osteonecrosis of the femoral head in the population of northern China.
Osteoporosis
Investigation of the relationship between osteoporosis and the collagenase gene by means of polymorphism of the 5'upstream region of this gene.
Osteoporosis
Membrane-type matrix metalloproteinase-1 (MT1-MMP) is down-regulated in estrogen-deficient rat osteoblast in vivo.
Osteosarcoma
A furin inhibitor downregulates osteosarcoma cell migration by downregulating the expression levels of MT1-MMP via the Wnt signaling pathway.
Osteosarcoma
Co-localisation of intra-nuclear membrane type-1 matrix metalloproteinase and hypoxia inducible factor-2? in osteosarcoma and prostate carcinoma cells.
Osteosarcoma
Colchicine induces membrane-associated activation of matrix metalloproteinase-2 in osteosarcoma cells in an S100A4-independent manner.
Osteosarcoma
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Osteosarcoma
Increased expression of membrane-type matrix metalloproteinase-1 is correlated with poor prognosis in patients with osteosarcoma.
Osteosarcoma
Influence of ?-catenin small interfering RNA on human osteosarcoma cells.
Osteosarcoma
Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Osteosarcoma
Matrix Metalloproteinase 1 promotes tumor formation and lung metastasis in an intratibial injection osteosarcoma mouse model.
Osteosarcoma
Parathyroid hormone induction of rat interstitial collagenase mRNA in osteosarcoma cells is mediated through an AP-1-binding site.
Osteosarcoma
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Osteosarcoma
Recombinant matrix metalloproteinase-14 catalytic domain induces apoptosis in human osteoblastic SaOS-2 cells.
Osteosarcoma
Retinoic acid stimulates interstitial collagenase messenger ribonucleic acid in osteosarcoma cells.
Osteosarcoma
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
Osteosarcoma
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.
Otitis Media
Serum matrix metalloproteinases and tympanosclerosis.
Ovarian Cysts
Study on matrix metalloproteinase 1 and 2 gene expression and NO in dairy cows with ovarian cysts.
Ovarian Neoplasms
Construction of antisense MT1-MMP vector and its inhibitory effects on invasion of human ovarian cancer cells.
Ovarian Neoplasms
Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells.
Ovarian Neoplasms
Epidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagen.
Ovarian Neoplasms
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Ovarian Neoplasms
Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.
Ovarian Neoplasms
Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation.
Ovarian Neoplasms
Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer.
Ovarian Neoplasms
Membrane-type I matrix metalloproteinase-dependent ectodomain shedding of mucin16/ CA-125 on ovarian cancer cells modulates adhesion and invasion of peritoneal mesothelium.
Ovarian Neoplasms
MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
Ovarian Neoplasms
MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells.
Ovarian Neoplasms
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
Ovarian Neoplasms
PEA3 is necessary for optimal epidermal growth factor receptor-stimulated matrix metalloproteinase expression and invasion of ovarian tumor cells.
Ovarian Neoplasms
Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP.
Ovarian Neoplasms
Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.
Ovarian Neoplasms
Post-translational modification of the membrane type 1 matrix metalloproteinase (MT1-MMP) cytoplasmic tail impacts ovarian cancer multicellular aggregate dynamics.
Ovarian Neoplasms
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Ovarian Neoplasms
Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis and tumor growth in ovarian cancer.
Ovarian Neoplasms
The role of MMP-14 in ovarian cancer: a systematic review.
Ovarian Neoplasms
[Inhibitory effect of MT1-MMP antisense nucleotide on invasion of human highly metastatic ovarian cancer cell line SW626.]
Pancreatic Neoplasms
Anti-tumor effect and mechanism of cyclooxygenase-2 inhibitor through matrix metalloproteinase 14 pathway in PANC-1 cells.
Pancreatic Neoplasms
CD44 regulates pancreatic cancer invasion through MT1-MMP.
Pancreatic Neoplasms
Localization of collagenase at the basal plasma membrane of a human pancreatic carcinoma cell line.
Pancreatic Neoplasms
Matrix metalloproteinase-14 is a mechanically regulated activator of secreted MMPs and invasion.
Pancreatic Neoplasms
MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management.
Pancreatic Neoplasms
MT1-MMP cooperates with KrasG12D to promote pancreatic fibrosis through increased TGF-{beta} signaling.
Pancreatic Neoplasms
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy.
Pancreatic Neoplasms
Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer.
Pancreatic Neoplasms
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Pancreatic Neoplasms
The Roles of Matrix Metalloproteinases in Pancreatic Cancer.
Pancreatitis
Long-term overexpression of membrane type-1 matrix metalloproteinase and matrix metalloproteinase-2 in oleic acid-induced pancreatitis in rats.
Pancreatitis, Chronic
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Papilloma
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Peri-Implantitis
Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study.
Periodontal Diseases
Involvement of MT1-MMP and TIMP-2 in human periodontal disease.
Periodontal Diseases
MMP-2 activation by Actinobacillus actinomycetemcomitans supernatant in human PDL cells was corresponded with reduction of TIMP-2.
Periodontal Pocket
Collagenase activity in gingival crevicular fluid of patients with juvenile periodontitis.
Periodontal Pocket
Effect of dental cyst epithelium-conditioned medium on collagenase production by periodontal ligament fibroblasts.
Periodontal Pocket
Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis.
Periodontitis
Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study.
Periodontitis
Membrane type (MT) 1-matrix metalloproteinase (MMP) and MMP-2 expression in ligature-induced periodontitis in the rat.
Periodontitis
Role of fibroblast populations in peri-implantitis.
Periodontitis
The relationship between mouthrinse matrix metalloproteinases (MMP-1, 8, 13) and albumin levels with the degree of oral mucositis in allogeneic stem cell transplant patients.
Pituitary Neoplasms
Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.
Pituitary Neoplasms
MMP-14 and TGF?-1 methylation in pituitary adenomas.
Pituitary Neoplasms
Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.
Pneumonia
Leukotriene C4 upregulates collagenase expression and synthesis in human lung fibroblasts.
Pneumonia
[The analysis of amount of matrix metalloproteinase 1 precursor, metalloproteinase 1 tissue inhibitor and cystatin C in the bronchoalveolar secretion of patients with nonspecific lung diseases].
Polycystic Kidney Diseases
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Polycystic Kidney, Autosomal Dominant
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Polycystic Kidney, Autosomal Dominant
Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.
Polyhydramnios
Amniotic fluid concentrations of collagenase-1 and collagenase-3 are increased in polyhydramnios.
Polymyositis
Expression of specific matrix metalloproteinases in inflammatory myopathies.
Polyneuropathies
MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy.
Pre-Eclampsia
Analyses of soluble endoglin and matrix metalloproteinase 14 using enzyme-linked immunosorbent assay in the diagnosis and assessment of severity of early- and late-onset pre-eclampsia
Pre-Eclampsia
Gene expression analysis of MMPs in women with preeclampsia using cell-free fetal RNA in maternal plasma.
Pre-Eclampsia
Matrix metalloproteinase 1 in pre-eclampsia and fetal growth restriction: reduced gene expression in decidual tissue and protein expression in extravillous trophoblasts.
Pre-Eclampsia
MMP-14 aggravates onset of severe preeclampsia by mediating soluble endoglin release.
Pre-Eclampsia
MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin.
Pre-Eclampsia
MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin.
Pregnancy, Tubal
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Pregnancy, Tubal
Membrane-type 1 matrix metalloproteinase is induced in decidual stroma without direct invasion by trophoblasts.
Pressure Ulcer
Nutritional markers, acute phase reactants and tissue inhibitor of matrix metalloproteinase 1 in elderly patients with pressure sores.
Prostatic Hyperplasia
Dual-functions of miR-373 and miR-520c by differently regulating the activities of MMP2 and MMP9.
Prostatic Hyperplasia
Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression.
Prostatic Intraepithelial Neoplasia
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Prostatic Neoplasms
Differential localization of MT1-MMP in human prostate cancer tissue: Role of IGF-1R in MT1-MMP expression.
Prostatic Neoplasms
Effect of hepatocyte growth factor on invasion of prostate cancer cell lines.
Prostatic Neoplasms
Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression.
Prostatic Neoplasms
Expression and functional role of CCR9 in prostate cancer cell migration and invasion.
Prostatic Neoplasms
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) on prostate cancer cell lines.
Prostatic Neoplasms
Increased Aggressiveness of Human Prostate PC-3 Tumor Cells Expressing Cell Surface Localized Membrane Type-1 Matrix Metalloproteinase (MT1-MMP).
Prostatic Neoplasms
Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.
Prostatic Neoplasms
LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells.
Prostatic Neoplasms
Loss of P53 facilitates invasion and metastasis of prostate cancer cells.
Prostatic Neoplasms
Lumican expression, localization and antitumor activity in prostate cancer.
Prostatic Neoplasms
Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.
Prostatic Neoplasms
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Prostatic Neoplasms
Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis.
Prostatic Neoplasms
Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration.
Prostatic Neoplasms
Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells.
Prostatic Neoplasms
OXIDATIVE STRESS AND PROSTATE CANCER PROGRESSION ARE ELICITED BY MEMBRANE-TYPE 1 MATRIX METALLOPROTEINASE (MT1-MMP).
Prostatic Neoplasms
Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
Prostatic Neoplasms
Prostate Cancer-Associated Membrane Type 1-Matrix Metalloproteinase. A Pivotal Role in Bone Response and Intraosseous Tumor Growth.
Prostatic Neoplasms
Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.
Prostatic Neoplasms
Roles of matrix metalloproteinases and their natural inhibitors in prostate cancer progression.
Prostatic Neoplasms
Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.
Prostatic Neoplasms
The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells.
Prostatic Neoplasms
Tumor-stroma interactions of metastatic prostate cancer cell lines: analyses using microarrays.
Prostatic Neoplasms
Underexpression of MMP-2 and its regulators, TIMP2, MT1-MMP and IL-8, is associated with prostate cancer.
Prostatic Neoplasms
VCA nanobodies target N-WASp to reduce invadopodium formation and functioning.
Prostatic Neoplasms
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
Prostatic Neoplasms
[Inhibitory effect of 3-bromopyruvate on the proliferation, migration and invasive ability of prostate cancer PC-3 cells].
Prostatic Neoplasms
[Prognostic value of stromal immunolabelling by MMP-2, MT1-MMP and TIMP-2 in clinically localized prostate cancer]
Proteinuria
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis.
Pterygium
Differential expression of matrix metalloproteinases and their tissue inhibitors at the advancing pterygium head.
Pterygium
UVB-elicited induction of MMP-1 expression in human ocular surface epithelial cells is mediated through the ERK1/2 MAPK-dependent pathway.
Pulmonary Disease, Chronic Obstructive
Activity of matrix metalloproteinase in airway epithelial cells of COPD patients.
Pulmonary Disease, Chronic Obstructive
Expression of matrix metalloproteinase-1 in alveolar macrophages, type II pneumocytes, and airways in smokers: relationship to lung function and emphysema.
Pulmonary Disease, Chronic Obstructive
Expression of Matrix Metalloproteinase-2, Matrix Metalloproteinase-9, Tissue Inhibitor of Metalloproteinase-1, and Changes in Alveolar Septa in Patients with Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses.
Pulmonary Disease, Chronic Obstructive
Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD.
Pulmonary Disease, Chronic Obstructive
[Complex search for antiprotease-protease enzyme gene polymorphisms in patients with chronic obstructive pulmonary diseases]
Pulmonary Disease, Chronic Obstructive
[Study on matrix metalloproteinase 1, 9, 12 polymorphisms and susceptibility to chronic obstructive pulmonary disease among Han nationality in northern China]
Pulmonary Disease, Chronic Obstructive
[The analysis of amount of matrix metalloproteinase 1 precursor, metalloproteinase 1 tissue inhibitor and cystatin C in the bronchoalveolar secretion of patients with nonspecific lung diseases].
Pulmonary Disease, Chronic Obstructive
[The expressions of TNF-alpha and MMP-9 in serum and MMP-1 mRNA in the bone tissue in chronic obstructive pulmonary disease patients of cold dryness syndrome in northwest China].
Pulmonary Emphysema
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke.
Pulmonary Fibrosis
Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis.
Pulmonary Fibrosis
Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits.
Pulmonary Fibrosis
[mRNA expression of matrix metalloproteinase-2 and membrane type matrix metalloproteinase in pulmonary fibroblasts and macrophages of rat pulmonary fibrosis model]
Pulpitis
Metalloproteinase 14 (MMP-14) and hsa-miR-410-3p expression in human inflamed dental pulp and odontoblasts.
Radicular Cyst
Immunolocalization of interstitial collagenase (MMP-1) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in radicular cysts.
Reperfusion Injury
Fibronectin-?4?1 Interactions in Hepatic Cold Ischemia and Reperfusion Injury: Regulation of MMP-9 and MT1-MMP via the p38 MAPK Pathway.
Respiratory Insufficiency
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Retinoblastoma
Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts.
Root Resorption
Expression of MT1-MMP during deciduous tooth resorption in odontoclasts.
Sarcoglycanopathies
Cleavage of ?-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9.
Sarcoma
Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines.
Sarcoma
Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
Sarcoma
Local activity of matrix metalloproteinases in a case of botryoid sarcoma.
Sarcoma
Matrix metalloproteinase 1: role in sarcoma biology.
Sarcoma
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Sarcoma
MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins.
Sarcoma, Ewing
DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.
Sarcoma, Ewing
Regulatory network of differentially expressed genes in metastatic osteosarcoma.
Scleroderma, Diffuse
Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls.
Scleroderma, Localized
Induction of interstitial collagenase (MMP-1) by UVA-1 phototherapy in morphea fibroblasts.
Scleroderma, Systemic
Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls.
Seizures
Focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior.
Seminoma
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Sepsis
Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases.
Silicosis
Egr-1 mediates Si0(2)-driven transcription of membrane type I matrix metalloproteinase in macrophages.
Skin Diseases
Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin.
Skin Diseases
Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease.
Skin Neoplasms
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
Skin Neoplasms
Increased expression of stromelysin-3 in basal cell carcinomas.
Skin Neoplasms
The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways.
Squamous Cell Carcinoma of Head and Neck
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Squamous Cell Carcinoma of Head and Neck
Discretionary Transduction of MMP-Sensitized Tousled in Head and Neck Cancer.
Squamous Cell Carcinoma of Head and Neck
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Squamous Cell Carcinoma of Head and Neck
Expression of MMP-7 and MT1-MMP in oral squamous cell carcinoma as predictive indicator for tumor invasion and prognosis.
Squamous Cell Carcinoma of Head and Neck
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Squamous Cell Carcinoma of Head and Neck
Identification of a novel therapeutic target for head and neck squamous cell carcinomas: a role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway.
Squamous Cell Carcinoma of Head and Neck
Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.
Squamous Cell Carcinoma of Head and Neck
Interstitial collagenase gene expression in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteases in head and neck cancer.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Squamous Cell Carcinoma of Head and Neck
Membrane type I-matrix metalloproteinase-mediated degradation of type I collagen by oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
Squamous Cell Carcinoma of Head and Neck
PLAU1 Facilitated Proliferation, Invasion, and Metastasis via Interaction With MMP1 in Head and Neck Squamous Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Podoplanin promotes the invasion of oral squamous cell carcinoma in coordination with MT1-MMP and Rho GTPases.
Squamous Cell Carcinoma of Head and Neck
Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer.
Squamous Cell Carcinoma of Head and Neck
[Correlation of membrane type I matrix metalloproteinase (MT1-MMP) expression with clinicomorphological features of tumor front in squamous cell carcinoma of the larynx]
Squamous Cell Carcinoma of Head and Neck
[Expression levels of MMP-14, ING4 and HIF-1? in 60 patients with oral squamous cell carcinoma and their clinical significance].
Squamous Cell Carcinoma of Head and Neck
[Expression of MMP1 mRNA in oral squamous cell carcinoma and paired normal tissues]
Starvation
mTOR Repression in Response to Amino Acid Starvation Promotes ECM Degradation Through MT1-MMP Endocytosis Arrest.
Starvation
TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis.
Stomach Neoplasms
A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases.
Stomach Neoplasms
Analysis of MT1-MMP and MMP2 expression in human gastric cancers.
Stomach Neoplasms
Balance between polyoma enhancing activator 3 and activator protein 1 regulates Helicobacter pylori-stimulated matrix metalloproteinase 1 expression.
Stomach Neoplasms
Clinical and experimental role of ring finger protein 180 on lymph node metastasis and survival in gastric cancer.
Stomach Neoplasms
Clinical significance of MT1-MMP mRNA expression in breast cancer.
Stomach Neoplasms
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Stomach Neoplasms
Combined features based on MT1-MMP expression, CD11b + immunocytes density and LNR predict clinical outcomes of gastric cancer.
Stomach Neoplasms
Contribution of matrix metalloproteinases-1 genotypes to gastric cancer susceptibility in Taiwan.
Stomach Neoplasms
Decreased MT1-MMP in gastric cancer suppressed cell migration and invasion via regulating MMPs and EMT.
Stomach Neoplasms
Down-regulation of KIF2A inhibits gastric cancer cell invasion via suppressing MT1-MMP.
Stomach Neoplasms
Downregulation of annexin A7 decreases proliferation, migration, and invasion of gastric cancer cells by reducing matrix metalloproteinase 1 and 9 expression.
Stomach Neoplasms
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Stomach Neoplasms
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Stomach Neoplasms
Exosomes derived from miR-1228 overexpressing bone marrow-mesenchymal stem cells promote growth of gastric cancer cells.
Stomach Neoplasms
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Stomach Neoplasms
Expression of interstitial collagenase (matrix metalloproteinase-1) in gastric cancers.
Stomach Neoplasms
Expression of MMP-14 and prognosis in digestive system carcinoma: a meta-analysis and databases validation.
Stomach Neoplasms
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Stomach Neoplasms
High serum MMP-14 predicts worse survival in gastric cancer.
Stomach Neoplasms
Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays.
Stomach Neoplasms
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis.
Stomach Neoplasms
Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway.
Stomach Neoplasms
Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.
Stomach Neoplasms
Letter regarding "MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies" by Wu KP et al.
Stomach Neoplasms
Matrix metalloproteinase gene expressions might be oxidative stress targets in gastric cancer cell lines.
Stomach Neoplasms
Matrix metalloproteinase-1 (MMP-1) Promoter polymorphisms are well linked with lower stomach tumor formation in eastern Indian population.
Stomach Neoplasms
Matrix Metalloproteinase-14 Is a Negative Prognostic Marker for Patients with Gastric Cancer.
Stomach Neoplasms
Membrane-type 1 matrix metalloproteinase enhances lymph node metastasis of gastric cancer.
Stomach Neoplasms
miRNA-337-3p inhibits gastric cancer progression through repressing myeloid zinc finger 1-facilitated expression of matrix metalloproteinase 14.
Stomach Neoplasms
miRNA-584-3p inhibits gastric cancer progression by repressing Yin Yang 1- facilitated MMP-14 expression.
Stomach Neoplasms
MT1-MMP is not a good prognosticator of cancer survival: evidence from 11 studies.
Stomach Neoplasms
Role of interstitial collagenase gene promoter polymorphism in the etiology of gastric cancer.
Stomach Neoplasms
The association between individual SNPs or haplotypes of matrix metalloproteinase 1 and gastric cancer susceptibility, progression and prognosis.
Stomach Neoplasms
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Stomach Neoplasms
The role of MT2-MMP in cancer progression.
Stomach Neoplasms
The role of stromal cells in the expression of interstitial collagenase (matrix metalloproteinase-1) in the invasion of gastric cancer.
Stomach Ulcer
Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin.
Stomach Ulcer
Spatial and temporal pattern of expression of interstitial collagenase, stromelysin/transin, gelatinase A, and TIMP-1 during experimental gastric ulcer healing.
Stomach Ulcer
Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin.
Stomatitis, Aphthous
Effect of tetracyclines on collagenase activity in patients with recurrent aphthous ulcers.
Stroke
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Stroke
Tissue Inhibitor of Matrix Metalloproteinase 1 Increases With Ageing and Can Be Associated With Stroke?- Nested Case-Control Study.
superoxide dismutase deficiency
Age-dependent increases in interstitial collagenase and MAP Kinase levels are exacerbated by superoxide dismutase deficiencies.
Synovitis
Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
Tendinopathy
Increased expression of matrix metalloproteinase 1 (MMP1) in 11 patients with patellar tendinosis.
Thrombosis
Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin.
Thrombosis
Expression changes and roles of matrix metalloproteinases in a rat model of traumatic deep vein thrombosis.
Thrombosis
Granulocytes in coronary thrombus evolution after myocardial infarction - time-dependent changes in expression of matrix metalloproteinases.
Thrombosis
Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
Thrombosis
Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity.
Thrombosis
Recanalization and flow regulate venous thrombus resolution and matrix metalloproteinase expression in vivo.
Thrombosis
Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.
Thymoma
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Thymoma
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
Thyroid Cancer, Papillary
Matrix metalloproteinase (MMP) expression by differentiated thyroid carcinoma of children and adolescents.
Thyroid Neoplasms
Expression of MMP-1 in invasive well-differentiated thyroid carcinoma.
Thyroid Neoplasms
Matrix metalloproteinase (MMP) expression by differentiated thyroid carcinoma of children and adolescents.
Thyroid Neoplasms
mRNA levels of membrane-type 1 matrix metalloproteinase (MT1-MMP), MMP-2, and MMP-9 and of their inhibitors TIMP-2 and TIMP-3 in normal thyrocytes and thyroid carcinoma cell lines.
Thyroid Neoplasms
Purification of aminophenyl mercuryacetate-activated human matrix metalloproteinase 1 and removal of the organomercurial in a single-step chromatography.
Thyroid Neoplasms
Relaxin enhances the collagenolytic activity and in vitro invasiveness by upregulating matrix metalloproteinases in human thyroid carcinoma cells.
Tics
Conversion of stationary to invasive tumor initiating cells (TICs): role of hypoxia in membrane type 1-matrix metalloproteinase (MT1-MMP) trafficking.
Tooth Resorption
Expression of MT1-MMP during deciduous tooth resorption in odontoclasts.
Triple Negative Breast Neoplasms
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Triple Negative Breast Neoplasms
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.
Triple Negative Breast Neoplasms
Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors.
Triple Negative Breast Neoplasms
Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function.
Triple Negative Breast Neoplasms
HRS-WASH axis governs actin-mediated endosomal recycling and cell invasion.
Triple Negative Breast Neoplasms
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
Tuberculosis
Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis.
Tuberculosis
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.
Urinary Bladder Neoplasms
Clinical significance and prognostic value of S100A4 and matrix metalloproteinase-14 in patients with organ-confined bladder cancer.
Urinary Bladder Neoplasms
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Urinary Bladder Neoplasms
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Urinary Bladder Neoplasms
p85? Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation.
Urinary Bladder Neoplasms
Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells.
Urinary Bladder Neoplasms
Soluble Expression of Bladder Cancer Biomarker Matrix Metalloproteinase 1.
Urinary Bladder Neoplasms
Tumor collagenase stimulating factor (TCSF) and tumor autocrine motility factor (TAMF) in bladder cancer.
Uterine Cervical Neoplasms
AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis.
Uterine Cervical Neoplasms
E6/E7 oncoproteins of high risk HPV-16 upregulate MT1-MMP, MMP-2 and MMP-9 and promote the migration of cervical cancer cells.
Uterine Cervical Neoplasms
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Uterine Cervical Neoplasms
Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion.
Uterine Cervical Neoplasms
HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases.
Uterine Cervical Neoplasms
Human Plasma Levels of Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, and Tissue Inhibitor of Matrix Metalloproteinase 1 and Their Applicability as Tumor Markers in Diagnoses of Cervical Cancer Based on ROC Analysis.
Uterine Cervical Neoplasms
Matrix metalloproteinase 1 gene polymorphism as a prognostic predictor of invasive cervical cancer.
Uterine Cervical Neoplasms
NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP.
Uterine Cervical Neoplasms
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
Uterine Cervical Neoplasms
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Vaccinia
Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.
Vascular Diseases
Analysis of apolipoprotein A-I as a substrate for matrix metalloproteinase-14.
Vascular Diseases
MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.
Vascular Diseases
Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.
Vascular Diseases
Role of MT1-MMP in Estrogen-Mediated Cellular Processes of Intimal Hyperplasia.
Vascular System Injuries
Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP.
Wiskott-Aldrich Syndrome
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.
Xeroderma Pigmentosum
Overexpression of matrix metalloproteinase 1 in dermal fibroblasts from DNA repair-deficient/cancer-prone xeroderma pigmentosum group C patients.
Xeroderma Pigmentosum
Pretreatment of Ferulic Acid Protects Human Dermal Fibroblasts against Ultraviolet A Irradiation.
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3.4.24.7 interstitial collagenase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
