Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 3.4.22.25 - glycyl endopeptidase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Polgar, L.
Isolation of highly active papaya peptidases A and B from commercial chymopapain
Biochim. Biophys. Acta
658
262-269
1981
Carica papaya
Manually annotated by BRENDA team
Ritonja, A.; Buttle, D.J.; Rawlings, N.D.; Turk, V.; Barrett, A.J.
Papaya proteinase IV amino acid sequence
FEBS Lett.
258
109-112
1989
Carica papaya
Manually annotated by BRENDA team
Buttle, D.J.; Ritonja, A.; Pearl, L.H.; Turk, V.; Barrett, A.J.
Selective cleavage of glycyl bonds by papaya proteinase IV
FEBS Lett.
260
195-197
1990
Carica papaya
Manually annotated by BRENDA team
Buttle, D.J.; Ritonja, A.; Dando, P.M.; Abrahamson, M.; Shaw, E.N.; Wikstrom, P.; Turk, V.; Barrett, A.J.
Interactions of papaya proteinase IV with inhibitors
FEBS Lett.
262
58-60
1990
BRENDA: Carica papaya
Textmining: Gallus gallus, Homo sapiens
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Buttle, D.J.
Glycyl endopeptidase
Methods Enzymol.
244
539-555
1994
Carica papaya
Manually annotated by BRENDA team
Sumner, I.G.; Harris, G.W.; Taylor, M.A.J.; Pickersgill, R.W.; Owen, A.J.; Goodenough, P.W.
Factors effecting the thermostability of cysteine proteinases from Carica papaya
Eur. J. Biochem.
214
129-134
1993
Carica papaya
Manually annotated by BRENDA team
Dekeyser, P.M.; Buttle, D.J.; Devreese, B.; van Beeumen, J.; Demeester, J.; Lauwers, A.
Kinetic constants for the hydrolysis of aggrecan by the papaya proteinases and their relevance for chemonucleolysis
Arch. Biochem. Biophys.
320
375-379
1995
Carica papaya
Manually annotated by BRENDA team
Buttle, D.J.; Kembhavi, A.A.; Sharp, S.L.; Shute, R.E.; Rich, D.H.; Barrett, A.J.
Affinity purification of the novel cysteine proteinase papaya proteinase IV, and papain from papaya latex
Biochem. J.
261
469-476
1989
BRENDA: Carica papaya
Textmining: plant, Gallus gallus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
O'Hara, B.P.; Hemmings, A.M.; Buttle, D.J.; Pearl, L.H.
Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity
Biochemistry
34
13190-13195
1995
Carica papaya
Manually annotated by BRENDA team
Thomas, M.P.; Verma, C.; Boyd, S.M.; Brocklehurst, K.
The structural origins of the unusual specificities observed in the isolation of chymopapain M and actinidin by covalent chromatography and the lack of inhibition of chymopapain M by cystatin
Biochem. J.
306
39-46
1995
Carica papaya
Manually annotated by BRENDA team
Topham, C.M.; Overington, J.; Thomas, M.; Kowlessur, D.; Thomas, E.W.; Brocklehurst, K.
Three-dimensional structure and thiol reactivity characteristics of chymopapain M (papaya proteinase IV)
Biochem. Soc. Trans.
18
934-935
1990
Carica papaya
Manually annotated by BRENDA team
Thomas, M.P.; Topham, C.M.; Kowlessur, D.; Mellor, G.W.; Thomas, E.W.; Whitford, D.; Brocklehurst, K.
Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ion-pair is insufficient for catalytic competence in both chymopapain M and papain
Biochem. J.
300
805-820
1994
Carica papaya
Manually annotated by BRENDA team
Goodenough, P.E.; Owen, J.
Chromatographic and electrophoretic analyses of papaya proteinases
Phytochemistry
26
75-79
1987
Carica papaya
-
Manually annotated by BRENDA team
Taylor, M.A.J.; Briggs, G.S.; Baker, K.C.; Cummings, N.J.; Pratt, K.A.; Freeman, R.B.; Goodenough, P.W.
Expression of the pro-regions of papain and papaya proteinase IV in Escherichia coli and their inhibition of mature cysteine proteinases
Biochem. Soc. Trans.
23
80S
1995
BRENDA: Carica papaya
Textmining: Escherichia coli
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Rowan, A.D.; Brzin, J.; Buttle, D.J.; Barrett, A.J.
Inhibition of cysteine proteinases by a protein inhibitor from potato
FEBS Lett.
269
328-330
1990
Carica papaya
Automatic Mining of ENzyme DAta
Maes, D.; Bouckaert, J.; Poortmans, F.; Wyns, L.; Looze, Y.
Structure of chymopapain at 1.7 A resolution
Biochemistry
35
16292-16298
1996
Carica papaya
Automatic Mining of ENzyme DAta
Buttle, D.J.; Dando, P.M.; Coe, P.F.; Sharp, S.L.; Shepherd, S.T.; Barrett, A.J.
The preparation of fully active chymopapain free of contaminating proteinases
Biol. Chem. Hoppe-Seyler
371
1083-1088
1990
Carica papaya
Automatic Mining of ENzyme DAta
Ritonja, A.; Colic, A.; Dolenc, I.; Ogrinc, T.; Podobnik, M.; Turk, V.
The complete amino acid sequence of bovine cathepsin S and a partial sequence of bovine cathepsin L
FEBS Lett.
283
329-331
1991
Carica papaya
Automatic Mining of ENzyme DAta
Visal, S.; Taylor, M.A.; Michaud, D.
The proregion of papaya proteinase IV inhibits Colorado potato beetle digestive cysteine proteinases
FEBS Lett.
434
401-405
1998
BRENDA: Carica papaya
Textmining: Leptinotarsa decemlineata, Escherichia coli, plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Azarkan, M.; El Moussaoui, A.; van Wuytswinkel, D.; Dehon, G.; Looze, Y.
Fractionation and purification of the enzymes stored in the latex of Carica papaya
J. Chromatogr. B
790
229-238
2003
Carica papaya
Manually annotated by BRENDA team
Huet, J.; Looze, Y.; Bartik, K.; Raussens, V.; Wintjens, R.; Boussard, P.
Structural characterization of the papaya cysteine proteinases at low pH
Biochem. Biophys. Res. Commun.
341
620-626
2006
BRENDA: Carica papaya
Textmining: plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Buttle, D.J.
Glycyl endopeptidase
Handbook of Proteolytic Enzymes (Barrett, A.J., Rawlings, N.D., Woessner, J.F., eds)
2
1132-1134
2004
Carica papaya
-
Manually annotated by BRENDA team
Chaiwut, P.; Kanasawud, P.; Halling, P.J.
Solid-to-solid peptide synthesis by glycyl endopeptidase
Enzyme Microb. Technol.
40
954-960
2007
Carica papaya (P05994)
-
Manually annotated by BRENDA team
Karnjanapratum, S.; Benjakul, S.
Glycyl endopeptidase from papaya latex: partial purification and use for production of fish gelatin hydrolysate
Food Chem.
165
403-411
2014
BRENDA: Carica papaya
Textmining: Chondrichthyes
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Liu, J.; Sharma, A.; Niewiara, M.; Singh, R.; Ming, R.; Yu, Q.
Papain-like cysteine proteases in Carica papaya lineage-specific gene duplication and expansion
BMC Genomics
19
26
2018
Carica papaya (P05994), Carica papaya
Manually annotated by BRENDA team
Jaziri, M; Kleinschmidt, T; Walraevens, V; Schnek, AG; Looze, Y
Primary structure of CC-III, the glycosylated cysteine proteinase from the latex of Carica candamarcensis Hook.
Biol Chem Hoppe Seyler
375
379-85
1994
Carica papaya
Automatic Mining of ENzyme DAta
Brunelle, F; Nguyen-Quoc, B; Cloutier, C; Michaud, D
Protein hydrolysis by colorado potato beetle, leptinotarsa decemlineata, digestive proteases: the catalytic role of cathepsin D
Arch Insect Biochem Physiol
42
88-98
1999
Leptinotarsa decemlineata, Carica papaya, Solanum tuberosum
Automatic Mining of ENzyme DAta
Machleidt, W; Nägler, DK; Assfalg-Machleidt, I; Stubbs, MT; Fritz, H; Auerswald, EA
Temporary inhibition of papain by hairpin loop mutants of chicken cystatin. Distorted binding of the loops results in cleavage of the Gly(9)-Ala10 bond.
FEBS Lett
361
185-90
1995
Carica papaya
Automatic Mining of ENzyme DAta
Taylor, MA; Baker, KC; Briggs, GS; Connerton, IF; Cummings, NJ; Pratt, KA; Revell, DF; Freedman, RB; Goodenough, PW
Recombinant pro-regions from papain and papaya proteinase IV-are selective high affinity inhibitors of the mature papaya enzymes.
Protein Eng
8
59-62
1995
Carica papaya, Escherichia coli
Automatic Mining of ENzyme DAta
Krizaj, I; Siigur, J; Samel, M; Cotic, V; Gubensek, F
Isolation, partial characterization and complete amino acid sequence of the toxic phospholipase A2 from the venom of the common viper, Vipera berus berus.
Biochim Biophys Acta
1157
81-5
1993
Carica papaya
Automatic Mining of ENzyme DAta
Song, I; Taylor, M; Baker, K; Bateman, RC
Inhibition of cysteine proteinases by Carica papaya cystatin produced in Escherichia coli.
Gene
162
221-4
1995
Carica papaya
Automatic Mining of ENzyme DAta
Dando, PM; Sharp, SL; Buttle, DJ; Barrett, AJ
Immunoglobulin E antibodies to papaya proteinases and their relevance to chemonucleolysis.
Spine
20
981-5
1995
Carica papaya, plant
Automatic Mining of ENzyme DAta
Dekeyser, PM; De Smedt, S; Demeester, J; Lauwers, A
Fractionation and purification of the thiol proteinases from papaya latex.
J Chromatogr B Biomed Appl
656
203-8
1994
Carica papaya
Automatic Mining of ENzyme DAta
El Moussaoui, A; Nijs, M; Paul, C; Wintjens, R; Vincentelli, J; Azarkan, M; Looze, Y
Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism.
Cell Mol Life Sci
58
556-70
2001
Carica papaya
Automatic Mining of ENzyme DAta
Karnjanapratum, S; O'Callaghan, YC; Benjakul, S; O'Brien, N
Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysate from unicorn leatherjacket skin.
J Sci Food Agric
2015
Aluterus monoceros, Chondrichthyes
Automatic Mining of ENzyme DAta
Fox, T; Mason, P; Storer, AC; Mort, JS
Modification of S1 subsite specificity in the cysteine protease cathepsin B.
Protein Eng
8
53-7
1995
Carica papaya
Automatic Mining of ENzyme DAta
Nawata, S; Nakamura, K; Tanaka, T; Numa, F; Suminami, Y; Tsunaga, N; Kakegawa, H; Katunuma, N; Kato, H
Electrophoretic analysis of the "cross-class" interaction between novel inhibitory serpin, squamous cell carcinoma antigen-1 and cysteine proteinases.
Electrophoresis
18
784-9
1997
Carica papaya
Automatic Mining of ENzyme DAta