Reference on EC 3.4.22.25 - glycyl endopeptidase
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Polgar, L.
Isolation of highly active papaya peptidases A and B from commercial chymopapain
Biochim. Biophys. Acta
658
262-269
1981
Carica papaya
Ritonja, A.; Buttle, D.J.; Rawlings, N.D.; Turk, V.; Barrett, A.J.
Papaya proteinase IV amino acid sequence
FEBS Lett.
258
109-112
1989
Carica papaya
Buttle, D.J.; Ritonja, A.; Pearl, L.H.; Turk, V.; Barrett, A.J.
Selective cleavage of glycyl bonds by papaya proteinase IV
FEBS Lett.
260
195-197
1990
Carica papaya
Buttle, D.J.; Ritonja, A.; Dando, P.M.; Abrahamson, M.; Shaw, E.N.; Wikstrom, P.; Turk, V.; Barrett, A.J.
Interactions of papaya proteinase IV with inhibitors
FEBS Lett.
262
58-60
1990
BRENDA: Carica papaya
Textmining: Gallus gallus, Homo sapiens
Sumner, I.G.; Harris, G.W.; Taylor, M.A.J.; Pickersgill, R.W.; Owen, A.J.; Goodenough, P.W.
Factors effecting the thermostability of cysteine proteinases from Carica papaya
Eur. J. Biochem.
214
129-134
1993
Carica papaya
Dekeyser, P.M.; Buttle, D.J.; Devreese, B.; van Beeumen, J.; Demeester, J.; Lauwers, A.
Kinetic constants for the hydrolysis of aggrecan by the papaya proteinases and their relevance for chemonucleolysis
Arch. Biochem. Biophys.
320
375-379
1995
Carica papaya
Buttle, D.J.; Kembhavi, A.A.; Sharp, S.L.; Shute, R.E.; Rich, D.H.; Barrett, A.J.
Affinity purification of the novel cysteine proteinase papaya proteinase IV, and papain from papaya latex
Biochem. J.
261
469-476
1989
BRENDA: Carica papaya
Textmining: plant, Gallus gallus
O'Hara, B.P.; Hemmings, A.M.; Buttle, D.J.; Pearl, L.H.
Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity
Biochemistry
34
13190-13195
1995
Carica papaya
Thomas, M.P.; Verma, C.; Boyd, S.M.; Brocklehurst, K.
The structural origins of the unusual specificities observed in the isolation of chymopapain M and actinidin by covalent chromatography and the lack of inhibition of chymopapain M by cystatin
Biochem. J.
306
39-46
1995
Carica papaya
Topham, C.M.; Overington, J.; Thomas, M.; Kowlessur, D.; Thomas, E.W.; Brocklehurst, K.
Three-dimensional structure and thiol reactivity characteristics of chymopapain M (papaya proteinase IV)
Biochem. Soc. Trans.
18
934-935
1990
Carica papaya
Thomas, M.P.; Topham, C.M.; Kowlessur, D.; Mellor, G.W.; Thomas, E.W.; Whitford, D.; Brocklehurst, K.
Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ion-pair is insufficient for catalytic competence in both chymopapain M and papain
Biochem. J.
300
805-820
1994
Carica papaya
Goodenough, P.E.; Owen, J.
Chromatographic and electrophoretic analyses of papaya proteinases
Phytochemistry
26
75-79
1987
Carica papaya
-
Taylor, M.A.J.; Briggs, G.S.; Baker, K.C.; Cummings, N.J.; Pratt, K.A.; Freeman, R.B.; Goodenough, P.W.
Expression of the pro-regions of papain and papaya proteinase IV in Escherichia coli and their inhibition of mature cysteine proteinases
Biochem. Soc. Trans.
23
80S
1995
BRENDA: Carica papaya
Textmining: Escherichia coli
Rowan, A.D.; Brzin, J.; Buttle, D.J.; Barrett, A.J.
Inhibition of cysteine proteinases by a protein inhibitor from potato
FEBS Lett.
269
328-330
1990
Carica papaya
Maes, D.; Bouckaert, J.; Poortmans, F.; Wyns, L.; Looze, Y.
Structure of chymopapain at 1.7 A resolution
Biochemistry
35
16292-16298
1996
Carica papaya
Buttle, D.J.; Dando, P.M.; Coe, P.F.; Sharp, S.L.; Shepherd, S.T.; Barrett, A.J.
The preparation of fully active chymopapain free of contaminating proteinases
Biol. Chem. Hoppe-Seyler
371
1083-1088
1990
Carica papaya
Ritonja, A.; Colic, A.; Dolenc, I.; Ogrinc, T.; Podobnik, M.; Turk, V.
The complete amino acid sequence of bovine cathepsin S and a partial sequence of bovine cathepsin L
FEBS Lett.
283
329-331
1991
Carica papaya
Visal, S.; Taylor, M.A.; Michaud, D.
The proregion of papaya proteinase IV inhibits Colorado potato beetle digestive cysteine proteinases
FEBS Lett.
434
401-405
1998
BRENDA: Carica papaya
Textmining: Leptinotarsa decemlineata, Escherichia coli, plant
Azarkan, M.; El Moussaoui, A.; van Wuytswinkel, D.; Dehon, G.; Looze, Y.
Fractionation and purification of the enzymes stored in the latex of Carica papaya
J. Chromatogr. B
790
229-238
2003
Carica papaya
Huet, J.; Looze, Y.; Bartik, K.; Raussens, V.; Wintjens, R.; Boussard, P.
Structural characterization of the papaya cysteine proteinases at low pH
Biochem. Biophys. Res. Commun.
341
620-626
2006
BRENDA: Carica papaya
Textmining: plant
Buttle, D.J.
Glycyl endopeptidase
Handbook of Proteolytic Enzymes (Barrett, A.J., Rawlings, N.D., Woessner, J.F., eds)
2
1132-1134
2004
Carica papaya
-
Chaiwut, P.; Kanasawud, P.; Halling, P.J.
Solid-to-solid peptide synthesis by glycyl endopeptidase
Enzyme Microb. Technol.
40
954-960
2007
Carica papaya (P05994)
-
Karnjanapratum, S.; Benjakul, S.
Glycyl endopeptidase from papaya latex: partial purification and use for production of fish gelatin hydrolysate
Food Chem.
165
403-411
2014
BRENDA: Carica papaya
Textmining: Chondrichthyes
Liu, J.; Sharma, A.; Niewiara, M.; Singh, R.; Ming, R.; Yu, Q.
Papain-like cysteine proteases in Carica papaya lineage-specific gene duplication and expansion
BMC Genomics
19
26
2018
Carica papaya (P05994), Carica papaya
Jaziri, M; Kleinschmidt, T; Walraevens, V; Schnek, AG; Looze, Y
Primary structure of CC-III, the glycosylated cysteine proteinase from the latex of Carica candamarcensis Hook.
Biol Chem Hoppe Seyler
375
379-85
1994
Carica papaya
Brunelle, F; Nguyen-Quoc, B; Cloutier, C; Michaud, D
Protein hydrolysis by colorado potato beetle, leptinotarsa decemlineata, digestive proteases: the catalytic role of cathepsin D
Arch Insect Biochem Physiol
42
88-98
1999
Leptinotarsa decemlineata, Carica papaya, Solanum tuberosum
Machleidt, W; Nägler, DK; Assfalg-Machleidt, I; Stubbs, MT; Fritz, H; Auerswald, EA
Temporary inhibition of papain by hairpin loop mutants of chicken cystatin. Distorted binding of the loops results in cleavage of the Gly(9)-Ala10 bond.
FEBS Lett
361
185-90
1995
Carica papaya
Taylor, MA; Baker, KC; Briggs, GS; Connerton, IF; Cummings, NJ; Pratt, KA; Revell, DF; Freedman, RB; Goodenough, PW
Recombinant pro-regions from papain and papaya proteinase IV-are selective high affinity inhibitors of the mature papaya enzymes.
Protein Eng
8
59-62
1995
Carica papaya, Escherichia coli
Krizaj, I; Siigur, J; Samel, M; Cotic, V; Gubensek, F
Isolation, partial characterization and complete amino acid sequence of the toxic phospholipase A2 from the venom of the common viper, Vipera berus berus.
Biochim Biophys Acta
1157
81-5
1993
Carica papaya
Song, I; Taylor, M; Baker, K; Bateman, RC
Inhibition of cysteine proteinases by Carica papaya cystatin produced in Escherichia coli.
Gene
162
221-4
1995
Carica papaya
Dando, PM; Sharp, SL; Buttle, DJ; Barrett, AJ
Immunoglobulin E antibodies to papaya proteinases and their relevance to chemonucleolysis.
Spine
20
981-5
1995
Carica papaya, plant
Dekeyser, PM; De Smedt, S; Demeester, J; Lauwers, A
Fractionation and purification of the thiol proteinases from papaya latex.
J Chromatogr B Biomed Appl
656
203-8
1994
Carica papaya
El Moussaoui, A; Nijs, M; Paul, C; Wintjens, R; Vincentelli, J; Azarkan, M; Looze, Y
Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism.
Cell Mol Life Sci
58
556-70
2001
Carica papaya
Karnjanapratum, S; O'Callaghan, YC; Benjakul, S; O'Brien, N
Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysate from unicorn leatherjacket skin.
J Sci Food Agric
2015
Aluterus monoceros, Chondrichthyes
Fox, T; Mason, P; Storer, AC; Mort, JS
Modification of S1 subsite specificity in the cysteine protease cathepsin B.
Protein Eng
8
53-7
1995
Carica papaya
Nawata, S; Nakamura, K; Tanaka, T; Numa, F; Suminami, Y; Tsunaga, N; Kakegawa, H; Katunuma, N; Kato, H
Electrophoretic analysis of the "cross-class" interaction between novel inhibitory serpin, squamous cell carcinoma antigen-1 and cysteine proteinases.
Electrophoresis
18
784-9
1997
Carica papaya
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