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Information on EC 3.4.21.4 - trypsin and Organism(s) Homo sapiens
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3.4.21.4 trypsinSpecify your search results
Word Map
- 3.4.21.4
- soybean
- pancreas
- elastase
- pepsin
- thrombin
- amylase
- proteinases
- albumin
- lipase
- porcine
- collagenase
- pronase
- erythrocyte
- plasmin
- collagen
- kallikreins
- sephadex
- neuraminidase
- bean
- lectin
-
exocrine
- carboxypeptidase
- juice
- cathepsins
- coagulation
-
edman
- casein
- duodenal
- plasminogen
-
acinar
- aprotinin
-
cyanogen
- subtilisin
- zymogen
- heparin
-
radioimmunoassay
- midguts
- cholecystokinin
-
reversed-phase
- lysozyme
- venom
-
125i-labeled
- hydrolysates
-
protease-activated
- kinin
- tryptase
- flour
- phosphopeptides
-
hemagglutination
- hyaluronidase
- biotechnology
- synthesis
- food industry
- medicine
- analysis
The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
trypsin, at-ii, cationic trypsinogen, beta-trypsin, trypsin-like enzyme, mesotrypsin, trypsin a, cationic trypsin, anionic trypsinogen, anionic trypsin, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
alpha-trypsin
Anionic trypsinogen
-
-
-
-
beta-trypsin
-
-
-
-
Brain trypsinogen
-
-
-
-
Cationic trypsinogen
-
-
-
-
cocoonase
-
-
-
-
Mesotrypsinogen
-
-
-
-
parenzyme
-
-
-
-
parenzymol
-
-
-
-
pseudotrypsin
-
-
-
-
SET
-
-
-
-
sperm receptor hydrolase
-
-
-
-
tripcellim
-
-
-
-
tryptar
-
-
-
-
tryptase
trypure
-
-
-
-
alpha-trypsin
-
-
-
-
tryptase
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
-
-
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CAS REGISTRY NUMBER
COMMENTARY
9002-07-7
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
4-methylumbelliferyl-4-guanidinobenzoate + H2O
4-methylumbelliferol + 4-guanidinobenzoate
-
-
-
-
?
benzoyl-DL-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-DL-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
enhanced green fluorescent protein-T1 + H2O
?
-
enhanced green fluorescent protein-T1 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 20 and 8 kDa
-
-
?
enhanced green fluorescent protein-T2 + H2O
?
-
enhanced green fluorescent protein-T2 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 18 and 10 kDa
-
-
?
epithelial sodium channel + H2O
?
-
-
epithelial sodium channel cleavage and activation by isoform trypsin IV but not by trypsin I requires a critical cleavage site, i.e. Lys189 in the extracellular domain of the gamma-subunit
-
?
inter-alpha-trypsin inhibitor heavy chain H4 + H2O
?
-
inter-alpha-trypsin inhibitor heavy chain H4 is also a marker of acute ischemic stroke
-
-
?
L-Phe-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O
L-Phe-L-Pro-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
N-(p-tosyl)-Gly-Pro-Arg 4-nitroanilide + H2O
N-(p-tosyl)-Gly-Pro-Arg + 4-nitroaniline
-
-
-
-
?
N-acetyl-GTNRSSKGRSLIGKVDGTSHVTGKGVT-amide + H2O
SLIGKVDGTSHVTGKGVT-amide + N-acetyl-GTNRSSKGR
-
-
-
-
?
N-alpha-benzoyl-DL-arginine-4-nitroanilide + H2O
N-alpha-benzoyl-DL-arginine + 4-nitroaniline
-
-
-
-
?
N-benzoyl-DL-arginine 4-nitroanilide + H2O
N-benzoyl-DL-arginine + 4-nitroaniline
-
-
-
-
?
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine methyl ester + H2O
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine + methanol
-
-
-
-
?
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide + H2O
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine + 4-nitroaniline
-
-
-
-
?
N-benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
N-benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide + H2O
N-carbobenzyloxy-Gly-Pro-Arg + p-nitroaniline
-
-
-
-
?
pro-human defensin-5 + H2O
human defensin-5 + pro-human defensin-5 propeptide
-
pro-human defensin-5 in the intestinal lumen is processed by trypsin in a complex in which chymotrypsinogen is also cleaved for activation
-
-
?
proteinase-activated receptor PAR-1 + H2O
activated proteinase-activated receptor PAR-1
-
no activation by mesotrypsin in epithelial cells, but mesotrypsin activates PAR-1 in astrocytoma cells. Half-maximal response for both cationic and anionic trypsin at about 10-20 nM
-
-
?
proteinase-activated receptor PAR-2 + H2O
activated proteinase-activated receptor PAR-2
-
no activation by mesotrypsin in epithelial cells. Half-maximal response for both cationic and anionic trypsin at about 5 nM
-
-
?
proteinase-activated receptor PAR-3 + H2O
activated proteinase-activated receptor PAR-3
-
no activation by mesotrypsin in epithelial cells. Half-maximal response for both cationic and anionic trypsin at about 10-20 nM
-
-
?
tert-butoxycarbonyl-L-Gln-L-Ala-L-Arg-7-amido-4-methylcoumarin + H2O
tert-butoxycarbonyl-L-Gln-L-Ala-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
Z-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
Z-Gly-Pro-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
human cartilage collagen type II + H2O
?
-
use of enzyme and its regulators as markers of prognosis and disease activity in rheumatoid arthritis
-
-
?
additional information
?
-
-
enzyme pancreatic isoforms cationic trypsin and anionic trypsin show activity on human proteinase-activated receptors PAR-1, PAR-2, PAR-3 comparable to that of bovine pancreatic trypsin. Mesotrypsin cannot activate or disable proteinase-activated receptors in human epithelial cells, but activates PAR-1 in human astrocytoma cells
-
-
?
additional information
?
-
-
does not react with proteinase-activated receptor 2
-
-
?
additional information
?
-
-
exhibits a relatively high specificity for Lys/Arg-Ser/Thr peptide bonds
-
-
?
additional information
?
-
-
active 1918 pandemic flu viral neuraminidase is resistant to trypsin digestion
-
-
?
additional information
?
-
-
does not cleave enhanced green fluorescent protein-T1m and wild type enhanced green fluorescent protein
-
-
?
additional information
?
-
-
cleavage of the potentially inhibitory peptides by isozyme trypsin-3, substrate specificity, overview
-
-
?
additional information
?
-
-
trypsin shows protease and esterase activities
-
-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
enhanced green fluorescent protein-T1 + H2O
?
-
enhanced green fluorescent protein-T1 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 20 and 8 kDa
-
-
?
enhanced green fluorescent protein-T2 + H2O
?
-
enhanced green fluorescent protein-T2 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 18 and 10 kDa
-
-
?
human cartilage collagen type II + H2O
?
-
use of enzyme and its regulators as markers of prognosis and disease activity in rheumatoid arthritis
-
-
?
additional information
?
-
-
enzyme pancreatic isoforms cationic trypsin and anionic trypsin show activity on human proteinase-activated receptors PAR-1, PAR-2, PAR-3 comparable to that of bovine pancreatic trypsin. Mesotrypsin cannot activate or disable proteinase-activated receptors in human epithelial cells, but activates PAR-1 in human astrocytoma cells
-
-
?
additional information
?
-
-
active 1918 pandemic flu viral neuraminidase is resistant to trypsin digestion
-
-
?
additional information
?
-
-
does not cleave enhanced green fluorescent protein-T1m and wild type enhanced green fluorescent protein
-
-
?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Ca2+
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
alpha1-antitrypsin Pittsburgh
-
effective inhibitor, variant of alpha1-antitrypsin containing an Arg residue in place of the P1 Met358 in the reactive-site peptide bond
-
Aprotinin
-
very efficient inhibition of trypsin-1 and trypsin-2, but not of trypsin-4
Bauhinia variegata var. variegata trypsin inhibitor
-
i.e. BvvTI, a Kunitz-type inhibitor from seeds of the Camels foot tree, Bauhinia variegata var. variegata. The inhibitor is also capable of significant inhibition of the proliferation of nasopharyngeal cancer CNE-1 cells in a selective way and of inhibiting anti-HIV-1 reverse transcriptase activity, overview
-
clispin
-
a Clitocybe nebularis trypsin inhibitor variant, recombinantly expressed in Escherichia coli, highly specific towards trypsin, fast-acting, and tight-binding. Molecular cloning of the gene and cDNA encoding cnispin, overview
Clitocybe nebularis trypsin inhibitor
-
CnSPI, several inhibitor variants, separation by trypsin affinity chromatography. Possible regulatory role for CnSPIs in the endogenous proteolytic system of Clitocybe nebularis. Isolation from frozen fruiting bodies or basidiocarps
-
LEKTI
-
the LEKI gene encodes a 15-domain serine proteinase inhibitor, disulfide bonds are important for LEKTI function, noncompetitive mechanism, expression and purification of human LEKTI gene in Sf9
nexin-1
-
nexin-1 inhibits isozymes trypsin-1 ad trypsin-2, nexin-1 inhibits trypsin-4 and forms stable complexes only with this trypsin isoenzyme
-
Pefabloc SC
-
completely inhibits isoenzymes trypsin-1, trypsin-2, and trypsin-4
SVIGCWTKSIPPRPCFVK-amide
-
HV-BBI is a Bowman-Birk type protease inhibitor from the skin secretion of the Chinese Bamboo odorous frog Huia versabilis, SVIGCWTKSIPPRPCFVK-amide is a synthetic replicate of HV-BBI with the wild-type K (Lys8) residue in the presumed P1 position and is a potent, competitive, and reversible inhibitor of trypsin
SVIGCWTRSIPPRPCFVK-amide
-
HV-BBI is a Bowman-Birk type protease inhibitor from the skin secretion of the Chinese Bamboo odorous frog Huia versabilis, SVIGCWTRSIPPRPCFVK-amide is a synthetic replicate of HV-BBI with the mutant R (Arg8) residue in the presumed P1 position and is a competitive, and reversible inhibitor of trypsin with reduced potency compared to the wild type peptide SVIGCWTKSIPPRPCFVK-amide
tumor-associated trypsin inhibitor
-
specific inhibition of degradation of gelatin and collagen type II
-
tumor-associated trypsin inhibitor
-
very efficient inhibition of trypsin-1 and trypsin-2, but not of trypsin-4
-
tumor-associated trypsin inhibitor
-
i.e. TATI, endogenous inhjibitor expressed in the cytoplasm of colon mucosa and colorectal cancer cells, shows prognostic significance of tumour-specific TATI expression in colorectal cancer, inhibitor expression is associated with a significantly decreased overall survival of colon cancer patients, and with increased liver metastasis, overview
-
additional information
-
trypsin 4 is completely resistant to chymotryptic degradation
-
additional information
-
mesotrypsin exhibits complete resistance against wild-type alpha1-antitrypsin
-
additional information
-
trypsin activity decreases with age, trypsin activity correlates inversely with cholesterol concentration and plasmin and elastase activity
-
additional information
-
not inhibited by up to 0.05 mM SVIGCWTFSIPPRPCFVK-amide
-
additional information
-
identification of trypsin-3 binding peptides, and molecular modeling of the binding of peptides to isozyme trypsin-3. The degradation rate of peptides by trypsin correlates to their inhibitory efficacy, the most stable peptides being the most effective inhibitors, overview
-
additional information
-
determination of serum trypsin inhibitory capacity of plasma in psoriatic patients, which is increased compared to healthy persons
-
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
caerulein
-
trypsinogen activation to trypsin occurs with 10 nM caerulein, trypsinogen is activated to reach a trypsin level of 6 nM following 10 nM caerulein induction for 1 h
enterokinase
-
trypsinogens (0.0002 mM) are incubated at room temperature with 6-200 ng enterokinase in 0.1 M Tris (pH 8), containing 5 mM CaCl2 and 0.01% bovine serum albumin for 10-60 min
-
additional information
-
tryptase expression in human skin is significantly increased at 24 and 48 h postirradiation with ultraviolet, infrared, and heat treatment
-
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abruptio Placentae
Trophoblastic apoptosis in mice with preterm delivery and its suppression by urinary trypsin inhibitor.
Abscess
[Studies on efficiency of the digestive enzyme trypsin in inflammations and abscess formation in tooth, mouth and jaw region with special reference to administration in root canal therapy]
Acantholysis
Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation.
Acantholysis
Corticosteroids, aurothioglucose and soybean trypsin inhibitor do not prevent pemphigus antibody-induced acantholysis in vitro.
Acantholysis
The pathogenic role of pemphigus antibodies and proteinase in epidermal acantholysis.
Acidosis, Lactic
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Acne Vulgaris
The effects of trypsin on apoptosis, utriculi size, and skin elasticity in the Rhino mouse.
Acquired Immunodeficiency Syndrome
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
Acquired Immunodeficiency Syndrome
CATIONIC TRYPSIN: A PREDOMINANT PROTEINASE IN PACIFIC SAURY (COLOLABIS SAIRA) PYLORIC CECA
Acquired Immunodeficiency Syndrome
Role of HIV and CMV in the pathogenesis of retinitis and retinal vasculopathy in AIDS patients.
Acquired Immunodeficiency Syndrome
Stability of tuna trypsin-loaded alginate-chitosan beads in acidic stomach fluid and the release of active enzyme in a simulated intestinal tract environment.
Acquired Immunodeficiency Syndrome
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Acquired Immunodeficiency Syndrome
Trypsin inhibition: a potential cause of cobalamin deficiency common to the pathogenesis of Alzheimer-type dementia and AIDS dementia complex?
Acute Coronary Syndrome
Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability.
Acute Kidney Injury
Beneficial effects of the urinary trypsin inhibitor urinastatin on renal insults induced by gentamicin and mercuric chloride (HgCl2) poisoning.
Acute Kidney Injury
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Acute Kidney Injury
Evaluation of podocin in urine in horses using qualitative and quantitative methods.
Acute Kidney Injury
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Acute Kidney Injury
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
Acute Kidney Injury
Rapid accumulation of plasma acid-stable trypsin inhibitor in experimental acute renal injury.
Acute Kidney Injury
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
Acute Lung Injury
Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Acute Lung Injury
Does Urinary Trypsin Inhibitor Have a Role in Acute Lung Injury Induced by Pulmonary Contusion: A Basic Research in a Model of Rats.
Acute Lung Injury
Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes.
Acute Lung Injury
Effects of Urinary Trypsin Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury in Rabbits.
Acute Lung Injury
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Acute Lung Injury
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Acute Lung Injury
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
Acute Lung Injury
Urinary Trypsin Inhibitor Attenuates Acute Lung Injury by Improving Endothelial Progenitor Cells Functions.
Acute Lung Injury
Urinary trypsin inhibitor attenuates lipopolysaccharide-induced acute lung injury by blocking the activation of p38 mitogen-activated protein kinase.
Acute Lung Injury
Urinary Trypsin Inhibitor Attenuates Seawater-Induced Acute Lung Injury by Influencing the Activities of Nuclear Factor-?B and Its Related Inflammatory Mediators.
Adenocarcinoma
Action of dietary trypsin, pressed coffee oil, silymarin and iron salt on 1,2-dimethylhydrazine tumorigenesis by gavage.
Adenocarcinoma
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Adenocarcinoma
Characterization of novel genetic alterations in salivary gland secretory carcinoma.
Adenocarcinoma
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Adenocarcinoma
Demonstration of pancreatic secretory trypsin inhibitor in serum-free culture medium conditioned by the human pancreatic carcinoma cell line CAPAN-1.
Adenocarcinoma
Effects of trypsin on binding of insulin and concanavalin A and on glucose and proline transport in the R3230AC mammary adenocarcinoma.
Adenocarcinoma
Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
Adenocarcinoma
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Adenocarcinoma
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Adenocarcinoma
Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line.
Adenocarcinoma
Immunohistochemical analysis of pancreatic secretory trypsin inhibitor expression in pulmonary adenocarcinoma: its possible participation in scar formation of the tumor tissues.
Adenocarcinoma
Neutral proteinases and inhibitors secreted by human rectal adenocarcinoma cell line (RCM-1).
Adenocarcinoma
New human colorectal carcinoma cell lines that secrete proteinase inhibitors in vitro.
Adenocarcinoma
Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
Adenocarcinoma
Pancreatic secretory trypsin inhibitor immunoreactivity detected in serum-free culture medium of human pancreatic carcinoma cell line, CAPAN-1.
Adenocarcinoma
Production and characterization of monoclonal antibody to a 60-kD glycoprotein in ovarian carcinoma.
Adenocarcinoma
Protease Inhibitors Protect Bovine Colostrum or Chicken Egg Growth Factors from Pancreatic Enzyme Digestion in AGS Cells or Colitic Rats.
Adenocarcinoma
Rhizoma Pinelliae trypsin inhibitor separation, purification and inhibitory activity on the proliferation of BGC-823 gastric adenocarcinoma cells.
Adenocarcinoma
Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors.
Adenocarcinoma
Separation of induction and expression of tight junction formation mediated by proteinases.
Adenocarcinoma
Simplified methods for obtaining purified oocysts from mice and for growing Cryptosporidium parvum in vitro.
Adenocarcinoma
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Adenocarcinoma
Tumor markers CA 125, carcinoembryonic antigen and tumor-associated trypsin inhibitor in patients with cervical adenocarcinoma.
Adenocarcinoma
[Characteristics of the kallikreins in healthy and malignant (adenocarcinoma) mucous membrane of the human large intestine]
Adenocarcinoma
[Hereditary pancreatitis - a clinically relevant cause of pancreatic adenocarcinoma?]
Adenocarcinoma
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
Adenocarcinoma
[The effects of epidermal growth factor and its antibody on the growth of xenografts in athymic nude mice]
Adenocarcinoma of Lung
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Adenocarcinoma of Lung
Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling.
Adenocarcinoma of Lung
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Adenocarcinoma of Lung
Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.
Adenocarcinoma, Follicular
Monitoring of brightness temperature of suspension of follicular thyroid carcinoma cells in SHF range by radiothermometry.
Adenoma
Adrenocortical carcinoma. An immunohistochemical comparison with renal cell carcinoma.
Adenoma
Correlation between nucleolar organizer regions and cell proliferation in pancreatic acinar cell proliferative lesions in rats.
Adenoma
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Adenoma
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Adenoma
Transmembrane orientation of palmitoyl-CoA: lysophosphatidylcholine acyltransferase in microsomes isolated from an alveolar type II cell adenoma and rat liver.
Adenomatous Polyposis Coli
Spiking of serum specimens with exogenous reporter peptides for mass spectrometry based protease profiling as diagnostic tool.
Adrenocortical Carcinoma
Adrenocortical carcinoma. An immunohistochemical comparison with renal cell carcinoma.
Adrenocortical Hyperfunction
[Immunoreactive trypsin in the blood of patients with functional disorders of the adrenal cortex]
Adrenocortical Hyperfunction
[Immunoreactive trypsin in the blood serum of patients with endogenous hypercorticism]
Alagille Syndrome
Th-17 cells infiltrate the liver in human biliary atresia and are related to surgical outcome.
Albuminuria
Diagnosis of albuminuria by tryptic digestion and matrix-assisted laser desorption ionization/time-of-flight mass spectrometry.
alpha 1-Antitrypsin Deficiency
Chronic pancreatitis with alpha 1-antitrypsin deficiency: from uncontrolled trypsin activation?
alpha 1-Antitrypsin Deficiency
Liver disease in alpha-1-antitrypsin deficiency: prognostic indicators.
alpha 1-Antitrypsin Deficiency
Pi-Z phenotypes in a pulmonary clinic. Their prevalence and physiologic state.
Alzheimer Disease
Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes.
Alzheimer Disease
Alzheimer's disease amyloid peptide is encoded by two exons and shows similarity to soybean trypsin inhibitor.
Alzheimer Disease
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes.
Alzheimer Disease
Dietary Wheat Amylase Trypsin Inhibitors Impact Alzheimer's Disease Pathology in 5xFAD Model Mice.
Alzheimer Disease
Does the Kunitz domain from the Alzheimer's amyloid beta protein precursor inhibit a kallikrein responsible for post-translational processing of nerve growth factor precursor?
Alzheimer Disease
Evolutionary origin of a Kunitz-type trypsin inhibitor domain inserted in the amyloid beta precursor protein of Alzheimer's disease.
Alzheimer Disease
Fibrillar amyloid beta-protein inhibits the activity of high molecular weight brain protease and trypsin.
Alzheimer Disease
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Alzheimer Disease
Kunitz-type protease inhibitor found in rat mast cells. Purification, properties, and amino acid sequence.
Alzheimer Disease
Structural features of the Abeta amyloid fibril elucidated by limited proteolysis.
Alzheimer Disease
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease.
Alzheimer Disease
Trypsin inhibitor activities of fibroblasts increase with age of donor and are unaltered in familial Alzheimer's disease.
Alzheimer Disease
Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor.
Amyloidosis
On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis.
Anaphylaxis
The release of four mediators of immediate hypersensitivity from human leukemic basophils.
Anaphylaxis
Urinary trypsin inhibitor improves peripheral microcirculation and bronchospasm associated with systemic anaphylaxis in rabbits in vivo.
Anaphylaxis
[Anaphylactoid reaction to trypsin following local administration of Dontisolon ointment]
Anaphylaxis
[Changes in serum activity of trypsin in patients with bronchial asthma between attacks and during experimental anaphylactic shock]
Anemia
Physicochemical studies of equine infectious anemia virus. II. Sensitivity of the virus to trypsin.
Anemia
Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis.
Anemia, Hemolytic
Electrophoretic demonstration of heterozygosis in hereditary pyruvate kinase deficiency. An unusual method.
Anemia, Sickle Cell
Newborn screening for sickle cell disorders using tandem mass spectrometry: three years' experience of using a protocol to detect only the disease states.
Angina, Unstable
ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells.
Anthrax
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.
Anthrax
Using molecular docking, 3D-QSAR, and cluster analysis for screening structurally diverse data sets of pharmacological interest.
Appendicitis
[The activity of trypsin and proteolytic inhibitors in complicated forms of appendicitis in children]
Arteriosclerosis
[STUDIES ON TRYPSIN INHIBITOR AND ANTIPLASMIN IN HUMAN SERUM. II. ON VARIOUS DISEASES EXCEPT ARTERIOSCLEROSIS.]
Arthritis
6-sulphanilamidoindazole arthritis of rats: relation between acute-phase proteins, degree of arthritis and treatment with soybean trypsin inhibitor.
Arthritis
Analgesic and anti-edematogenic effects of oral trypsin were abolished after subdiaphragmatic vagotomy and spinal monoaminergic inhibition in rats.
Arthritis
Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals.
Arthritis
Pancreatic carcinoma with polyarthritis, fat necrosis, and high serum lipase and trypsin activity.
Arthritis
Suppression of streptococcal cell wall-induced arthritis by a potent protease inhibitor, bis(5-amidino-2-benzimidazolyl)methane.
Arthritis, Experimental
Inhibitory effect of enzyme therapy and combination therapy with cyclosporin A on collagen-induced arthritis.
Arthritis, Infectious
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Arthritis, Rheumatoid
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Arthritis, Rheumatoid
Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage.
Arthritis, Rheumatoid
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Arthritis, Rheumatoid
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue.
Ascariasis
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. V. Effects of administration of vitamin A and B 2 during the larval stage of ascariasis]
Asthma
A study of the binding of immunoglobulin G and immunoglobulin E from children with bronchial asthma to peptides derived from group II antigen of Dermatophagoides pteronyssinus.
Asthma
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Asthma
Exposure levels of asthmatic children to allergens, endotoxins, and serine proteases in a tropical environment.
Asthma
Expression and function of proteinase-activated receptor 2 in human bronchial smooth muscle.
Asthma
Genetic architecture underlying the expression of eight ?-amylase trypsin inhibitors.
Asthma
IgE mediated hypersensitivity to pancreatic extract (PE) in parents of cystic fibrosis (CF) children.
Asthma
Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation.
Asthma
Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.
Asthma
Protease-activated receptor-2 signaling through ?-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
Asthma
Protease-activated receptor-2-mediated Ca2+ signaling in guinea pig tracheal epithelial cells.
Asthma
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Asthma
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Asthma
[Changes in serum activity of trypsin in patients with bronchial asthma between attacks and during experimental anaphylactic shock]
Asthma
[Death during trypsin inhalation by an asthma patient under prolonged corticosteroid therapy]
Asthma
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
Asthma
[Immunotherapy effect of ploypeptide vaccine of allergen group 1 from Dermatophagoides farinae on asthma mice].
Asthma, Occupational
Immediate hypersensitivity to hog trypsin resulting from industrial exposure.
Astrocytoma
Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1.
Astrocytoma
Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes.
Astrocytoma
Production of amyloid beta protein precursor as a proteinase inhibitor by human astrocytic tumors.
Astrocytoma
The presence of distinct soluble and particulate trypsin inhibitors in human astrocytoma tissue.
Astrocytoma
The two-receptor system PAR-1/PAR-4 mediates alpha-thrombin-induced [Ca(2+)](i) mobilization in human astrocytoma cells.
Atherosclerosis
Carotid atherosclerotic plaques: proteomics study after a low-abundance protein enrichment step.
Atherosclerosis
Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability.
Atherosclerosis
[Improvements in the technical conditions for the evaluation of an elastolytic activity. The role of tryspin as an activator (author's transl)]
Autoimmune Diseases
In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans.
Autoimmune Diseases
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
Autoimmune Pancreatitis
Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis.
Bacteremia
Haemophilus influenzae b bacteremia and meningitis in infant rabbits after intranasal inoculation.
Bacteremia
Hemophilus influenzae type b meningitis in infant rabbits. Pathogenesis and therapy.
Bacterial Infections
Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy.
Bacterial Infections
JcTI-I: a novel trypsin inhibitor from Jatropha curcas seed cake with potential for bacterial infection treatment.
Bacterial Infections
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Bacterial Infections
Urinary trypsin inhibitory activity: not a useful test for detecting bacterial infections in elderly people.
Bacterial Infections
[Large recombinant protein displayed on filamentous phage surface and its interaction with small molecule]
Bile Reflux
The key event of acute pancreatitis: pancreatic duct obstruction and bile reflux, not a single one can be omitted.
Biliary Atresia
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
Biliary Fistula
Rat pancreatic response to intestinal infusion of intact and hydrolyzed protein.
Biliary Tract Diseases
[Analysis of trypsin inhibitor level and its fluctuation in pancreatic and biliary tract diseases]
Biliary Tract Neoplasms
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Blister
Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties.
Blister
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Blister
Dissociation of suction blister roof epidermis with trypsin and desoxyribonuclease into viable single cells.
Blister
Enriched epidermal Langerhans cells are potent antigen-presenting cells for T cells.
Blister
Origin and properties of the blister formation factor in blister fluids from recessive dystrophic epidermolysis bullosa.
Blister
Proteases are responsible for blister formation in recessive dystrophic epidermolysis bullosa and epidermolysis bullosa simplex.
Blister
Rounding and steroidogenesis of enzyme- and ACTH-treated Y-l mouse adrenal tumor cells.
Blister
Studies on human epidermal Langerhans cells III. Induction of T lymphocyte response to nickel sulphate in sensitized individuals.
Blister
Studies on human epidermal Langerhans cells. I. Allo-activating and antigen-presenting capacity.
Blister
Studies on human epidermal Langerhans' cells: II. Activation of human T lymphocytes to herpes simplex virus.
Blister
[Quantitative measurements on tryptic degradation of lactate dehydrogenase in human serum, skin blister fluid and sperm. A contribution to the problem of trypsin inhibitor.]
Blister
[Study of cantharides blister fluid in the analysis of the mechanism of action of trypsin in the treatment of chronic peripheral arterial diseases.]
Bluetongue
Effects of proteolytic enzymes on the infectivity, haemagglutinating activity and protein composition of bluetongue virus type 20.
Bluetongue
Sensitivity of bluetongue virus to lipid solvents, trypsin and pH changes and its serological relationship to arboviruses.
Brain Contusion
Significant elevation of urinary trypsin inhibitor in patients with brain contusion - a preliminary report.
Brain Death
Protective effects of urinary trypsin inhibitor (UTI) on hepatic microvasculature in hypotensive brain-dead rats.
Brain Diseases
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
Brain Diseases
Raised serum immunoreactive trypsin in the haemorrhagic shock and encephalopathy syndrome.
Brain Edema
[Effect of trypsin inhibitor on cerebral edema associated with cerebrovascular diseases]
Brain Edema
[Studies on the involvement of bradykinin in the formation of ischemic brain edema]
Brain Injuries
Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy.
Brain Injuries
The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model.
Brain Neoplasms
cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Brain Neoplasms
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Breast Neoplasms
A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer.
Breast Neoplasms
A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans.
Breast Neoplasms
Binding of transferrin to membrane-associated proteoglycans in breast-cancer cells.
Breast Neoplasms
Brown Kidney Bean Bowman-Birk Trypsin Inhibitor is Heat and pH Stable and Exhibits Anti-proliferative Activity.
Breast Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Breast Neoplasms
Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase.
Breast Neoplasms
Characterization and microarray analysis of genes in human lymphatic endothelial cells from patients with breast cancer.
Breast Neoplasms
Co-Expression of a Chimeric Protease Inhibitor Secreted by a Tumor-Targeted Salmonella Protects Therapeutic Proteins from Proteolytic Degradation.
Breast Neoplasms
Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.
Breast Neoplasms
CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2).
Breast Neoplasms
Early diagnostic protein biomarkers for breast cancer: how far have we come?
Breast Neoplasms
Enhanced killing of breast cancer cells by a d-amino acid analog of the winter flounder-derived pleurocidin NRC-03.
Breast Neoplasms
Increase in the estrogen binding capacity of breast cancer cytosols following limited proteolysis with trypsin.
Breast Neoplasms
MALDI-TOF mass spectrometry analysis of cerebrospinal fluid tryptic peptide profiles to diagnose leptomeningeal metastases in patients with breast cancer.
Breast Neoplasms
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Breast Neoplasms
Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis.
Breast Neoplasms
Proteinase-activated receptor-2 expression in breast cancer and the role of trypsin on growth and metabolism of breast cancer cell line MDA MB-231.
Breast Neoplasms
Purification and identification of a 28-kDa calcium-regulated heat-stable protein. A novel secretagogue-regulated phosphoprotein in exocrine pancreas.
Breast Neoplasms
Searching for early breast cancer biomarkers by serum protein profiling of pre-diagnostic serum; a nested case-control study.
Breast Neoplasms
Serum proteomic biomarker discovery reflective of stage and obesity in breast cancer patients.
Breast Neoplasms
Serum tumour markers CA 15-3, TPA, TPS, hCGbeta and TATI in the monitoring of chemotherapy response in metastatic breast cancer.
Breast Neoplasms
Steroid sequestration and tightly bound oestrogen-protein complexes in human breast tumours and a breast cancer cell line.
Breast Neoplasms
The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.
Breast Neoplasms
The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
Breast Neoplasms
Urinary cancer-related protein EDC1 and serum inter-alpha trypsin inhibitor in breast cancer.
Bronchial Diseases
[Significance of enzyme therapy with oral trypsin and chymotrypsin in chronic bronchial diseases in the course of inhalatory balneotherapy and of pulmonary ventilation]
Bronchial Diseases
[Use of combined trypsin and antibiotics in inhalation therapy of some bronchial diseases.]
Bronchial Spasm
Pharmacological Evaluation of Antiasthmatic Activity of Myrica nagi Bark Extracts.
Bronchial Spasm
Urinary trypsin inhibitor improves peripheral microcirculation and bronchospasm associated with systemic anaphylaxis in rabbits in vivo.
Bronchiolitis
Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis.
Bronchitis
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Bronchitis
Effect of different passage histories of infectious bronchitis virus on the sensitivity to inhibitors in chick serum and their removal by trypsin.
Bronchitis
Plaque formation by avian infectious bronchitis virus in primary chick embryo fibroblast cells in the presence of trypsin.
Bronchitis
Treatment of asthmatic bronchitis with drugs, administered as an aerosol; the profit of pneumotachography in judging its merits, trypsin a powerful new drug.
Bronchitis
Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus.
Bronchitis
[Replication characteristics and cytopathic effect of southern German field isolates of chicken infectious bronchitis virus in cell cultures and the effect of trypsin]
Bronchitis
[Therapy with hormonal preparations and trypsin of a patient with plastic bronchitis]
Bronchitis, Chronic
[Effectiveness of trypsin electrophoresis in treating chronic bronchitis]
Bronchopulmonary Dysplasia
Limited fat digestion in infants with bronchopulmonary dysplasia.
Bronchopulmonary Dysplasia
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Bronchopulmonary Dysplasia
Serial trypsin inhibitory capacity and ceruloplasmin levels in prematures at risk for bronchopulmonary dysplasia.
Burkitt Lymphoma
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Calciphylaxis
[STUDIES ON THE EFFECTS OF A TRYPSIN INHIBITOR (TRASYLOL) ON ENZYME ACTIVITIES AND MORPHOLOGY IN TAUROCHOLATE AND CALCIPHYLAXIS PANCREATITIS OF THE RAT (A CONTRIBUTION TO THE PATHOGENESIS OF PANCREATITIS. II.)]
Candidiasis
Cell preparation method with trypsin digestion for counting of colony forming units in Candida albicans-infected mucosal tissues.
Candidiasis, Oral
Cell preparation method with trypsin digestion for counting of colony forming units in Candida albicans-infected mucosal tissues.
Carcinogenesis
Action of dietary trypsin, pressed coffee oil, silymarin and iron salt on 1,2-dimethylhydrazine tumorigenesis by gavage.
Carcinogenesis
Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells.
Carcinogenesis
Blocking effects of synthetic trypsin inhibitor (camostat) on pancreatic carcinogenesis in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Blood serum alpha fetoprotein enhancer binding protein, a tumor suppressor, decreases in chronic HBV hepatitis patients as hepatocellular cancer appears.
Carcinogenesis
Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1.
Carcinogenesis
Early indicators of exocrine pancreas carcinogenesis produced by non-genotoxic agents.
Carcinogenesis
Effects of dietary soya bean trypsin inhibitor concentrate on initiation and growth of putative preneoplastic lesions in the pancreas of the rat.
Carcinogenesis
Impairment of alveolar type-II cells involved in the toxicity of Aflatoxin G(1) in rat lung.
Carcinogenesis
Inhibitory effects of crude soybean trypsin inhibitor on pancreatic ductal carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Inhibitory effects of soybean trypsin inhibitor during initiation and promotion phases of N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis.
Carcinogenesis
Inhibitory effects of soybean trypsin inhibitor on induction of pancreatic neoplastic lesions in hamsters by N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Carcinogenesis
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Carcinogenesis
Marginal zinc status does not exacerbate pancreatic carcinogenesis associated with dietary soybean trypsin inhibitor concentrate in rats.
Carcinogenesis
Prostate adenocarcinoma and COVID-19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS-CoV-2.
Carcinogenesis
Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder.
Carcinogenesis
Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Carcinogenesis
Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Carcinogenesis
Stimulation of the growth of azaserine-induced nodules in the rat pancreas by dietary camostate (FOY-305).
Carcinogenesis
Suppression of 3-methylcholanthrene-induced cellular transformation by timed administration of the Bowman-Birk protease inhibitor.
Carcinogenesis
The effects on cellular functions of bile acid and trypsin in stagnant bile juice in anomalous arrangement of the pancreaticobiliary duct.
Carcinogenesis
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Carcinogenesis
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
Carcinogenesis
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Carcinoid Tumor
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
Carcinoma
A comparative evaluation of the ability of serum CA 125, CA 19-9, CA 15-3, CA 50, CA 72-4 and TATI assays in reflecting the course of disease in patients with ovarian carcinoma.
Carcinoma
A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening.
Carcinoma
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Carcinoma
Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.
Carcinoma
Analyte-activable probe for protease based on cytochrome C-capped Mn: ZnS quantum dots.
Carcinoma
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Carcinoma
Assessment of the tumor-associated trypsin inhibitor (TATI) marker in patients with carcinoma of the uterine body 17 years after treatment.
Carcinoma
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Carcinoma
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Carcinoma
Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder.
Carcinoma
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Carcinoma
Bcl-10, trypsin and synaptophysin helps recognize acinar cell and mixed acinar neuroendocrine cell carcinoma of the pancreas on both preoperative cytological samples and needle biopsy specimens.
Carcinoma
Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma.
Carcinoma
Characterisation of changes in the proteome in different regions of 3D multicell tumor spheroids.
Carcinoma
Characterization of structural domains of the human epidermal growth factor receptor obtained by partial proteolysis.
Carcinoma
Chemotherapy as initial treatment for cervical carcinoma: clinical and tumor marker response.
Carcinoma
Clinicopathologic study of 62 acinar cell carcinomas of the pancreas: insights into the morphology and immunophenotype and search for prognostic markers.
Carcinoma
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Carcinoma
Coagulative and fibrinolytic properties of ascitic fluid associated with ovarian tumors.
Carcinoma
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Carcinoma
Concentrations of protease and anti-protease in serum of patients with pancreatic cancer.
Carcinoma
Cytokeratin 8-MHC class I interactions: a potential novel immune escape phenotype by a lymph node metastatic carcinoma cell line.
Carcinoma
Demonstration of pancreatic secretory trypsin inhibitor in serum-free culture medium conditioned by the human pancreatic carcinoma cell line CAPAN-1.
Carcinoma
Development of ionic strength/pH/enzyme triple-responsive zwitterionic hydrogel of the mixed l-glutamic acid and l-lysine polypeptide for site-specific drug delivery.
Carcinoma
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Carcinoma
Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
Carcinoma
Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.
Carcinoma
Effect of bombesin administration on serum immunoreactive trypsin in patients with pancreatic carcinoma.
Carcinoma
Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
Carcinoma
Effect of secretin stimulation upon serum immunoreactive trypsin in patients with carcinoma of the pancreas.
Carcinoma
Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
Carcinoma
Enhancement of mechanisms acting against mammary carcinoma: pancreatic trypsin inhibitor.
Carcinoma
Enzymatic modulation of the cell surface in malignant transformation of normal human mammary epithelial cells and in conversion of mammary carcinoma cells.
Carcinoma
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma.
Carcinoma
Evaluation of urine tumor-associated trypsin inhibitor, CYFRA 21-1, and urinary bladder cancer antigen for detection of high-grade bladder carcinoma.
Carcinoma
Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation.
Carcinoma
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Carcinoma
Expression of urokinase and urinary trypsin inhibitor in metastatic and non-metastatic murine Lewis lung carcinoma cells.
Carcinoma
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Carcinoma
Immunohistochemical study on pancreatic secretory trypsin inhibitor (PSTI) in gastric carcinomas.
Carcinoma
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Carcinoma
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Carcinoma
Intraductal polypoid growth variant of pancreatic acinar cell carcinoma metastasizing to the intrahepatic bile duct 6 years after surgery: a case report and literature review.
Carcinoma
Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling.
Carcinoma
Investigations of conformational structure and enzymatic activity of trypsin after its binding interaction with graphene oxide.
Carcinoma
Isolation and serial propagation of human group C rotaviruses in a cell line (CaCo-2).
Carcinoma
Isolation of alpha 1-protease inhibitor from human normal and malignant ovarian tissue.
Carcinoma
Isolation of Enterococcus faecalis clinical isolates that efficiently adhere to human bladder carcinoma T24 cells and inhibition of adhesion by fibronectin and trypsin treatment.
Carcinoma
Limited loss of nine tumor-associated surface antigenic determinants after tryptic cell dissociation.
Carcinoma
Lipase hypersecretion syndrome: A distinct form of paraneoplastic syndrome specific to pancreatic acinar carcinomas.
Carcinoma
MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
Carcinoma
Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
Carcinoma
Pancreatic carcinoma with polyarthritis, fat necrosis, and high serum lipase and trypsin activity.
Carcinoma
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Carcinoma
Pancreatic secretory trypsin inhibitor immunoreactivity detected in serum-free culture medium of human pancreatic carcinoma cell line, CAPAN-1.
Carcinoma
Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
Carcinoma
Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
Carcinoma
Preoperative serum hCGbeta as a prognostic marker in primary fallopian tube carcinoma.
Carcinoma
Quantification of pancreatic secretory trypsin inhibitor in colonic carcinoma and normal adjacent colonic mucosa.
Carcinoma
Rapid aggregation and tight junction formation in single cell suspensions of tumor cells after very low dose trypsin treatment.
Carcinoma
Renal function and serum concentration of five tumor markers (TATI, SCC, CYFRA 21-1, TPA, and TPS) in patients without evidence of neoplasia.
Carcinoma
Reverse-zymographic analysis of protease nexin-II/amyloid beta protein precursor of human carcinoma cell lines, with special reference to the grade of differentiation and metastatic phenotype.
Carcinoma
Secretion of pancreatic secretory trypsin inhibitor by cultured human carcinoma cells.
Carcinoma
Separation and characterization of epithelial cells from prostates and prostatic carcinomas: a review.
Carcinoma
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Carcinoma
Serum alpha-1 proteinase inhibitor in advanced cancer: mass variants and functionally inert forms.
Carcinoma
Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
Carcinoma
Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
Carcinoma
Specificity of reagents directed to the Thomsen-Friedenreich antigen and their capacity to bind to the surface of human carcinoma cell lines.
Carcinoma
Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NF??B via an AKT?independent pathway.
Carcinoma
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Carcinoma
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Carcinoma
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
Carcinoma
Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
Carcinoma
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Carcinoma
Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells.
Carcinoma
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Carcinoma
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Carcinoma
Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Carcinoma
Trypsin-2 Enhances Carcinoma Invasion by Processing Tight Junctions and Activating ProMT1-MMP.
Carcinoma
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Carcinoma
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Carcinoma
Tumor-associated trypsin inhibitor in normal and malignant renal tissue and in serum of renal-cell carcinoma patients.
Carcinoma
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Carcinoma
Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder.
Carcinoma
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
Carcinoma
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
Carcinoma
[Significance of the the tumor markers, Ca-125 and tumor-associated trypsin inhibitor in patients with carcinoma of the cervix and uterus]
Carcinoma
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Carcinoma
[Uniform method for determining the alpha 1-antitrypsin and alpha 2-macroglobulin activity in human blood serum (plasma)]
Carcinoma, Acinar Cell
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Carcinoma, Acinar Cell
Differentiation of pancreatic acinar carcinoma cells cultured on rat testicular seminiferous tubular basement membranes.
Carcinoma, Acinar Cell
Intraductal polypoid growth variant of pancreatic acinar cell carcinoma metastasizing to the intrahepatic bile duct 6 years after surgery: a case report and literature review.
Carcinoma, Acinar Cell
Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
Carcinoma, Acinar Cell
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Carcinoma, Adenosquamous
Bcl-10, trypsin and synaptophysin helps recognize acinar cell and mixed acinar neuroendocrine cell carcinoma of the pancreas on both preoperative cytological samples and needle biopsy specimens.
Carcinoma, Bronchogenic
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Carcinoma, Ehrlich Tumor
beta-Naphthylamidase activity of the cell surface of ehrlich ascites cells. Reversible control of enzyme activity by metal ions and thiols.
Carcinoma, Ehrlich Tumor
Biphasic kinetics of metal ion reactivation of trypsin-thiol complexes.
Carcinoma, Ehrlich Tumor
Changes in growth and adhesion of Ehrlich ascites tumour cells coated with trypsin inhibitor (soybean).
Carcinoma, Ehrlich Tumor
Characterization of plasma membrane redox activity from Ehrlich cells.
Carcinoma, Ehrlich Tumor
Effect of crude trypsin on incorporation of 3H-thymidine and 3H-uridine into the Ehrlich ascites tumour cells.
Carcinoma, Ehrlich Tumor
Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
Carcinoma, Ehrlich Tumor
Growth acceleration of Ehrlich ascites tumor cells treated by proteinase in vitro.
Carcinoma, Ehrlich Tumor
Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.
Carcinoma, Ehrlich Tumor
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
Carcinoma, Ehrlich Tumor
Mg2+- or Mn2+-dependent p-nitrophenylphosphatase activity is present in Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Proceedings: Independent responses of different binding sites on ehrlich ascites tumour cells to trypsin and trypsin inhibitor.
Carcinoma, Ehrlich Tumor
Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
Carcinoma, Ehrlich Tumor
The interaction of a trypsin-dependent neutral protease and its inhibitor found in tumour cells. Analysis of complex kinetic data involved in a thiol-disulphide exchange mechanism.
Carcinoma, Hepatocellular
A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans.
Carcinoma, Hepatocellular
Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells.
Carcinoma, Hepatocellular
Brain- and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture.
Carcinoma, Hepatocellular
Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma.
Carcinoma, Hepatocellular
Clinical and prognostic significance of urinary trypsin inhibitor in patients with hepatocellular carcinoma after hepatectomy.
Carcinoma, Hepatocellular
Cytotoxicity of tumour-bearer serum to D23 hepatoma cells derived from solid tumours, ascites or in vitro cultures.
Carcinoma, Hepatocellular
Differences in cholesterol incorporation into mitochondria from hepatoma AS-30D and human term placenta.
Carcinoma, Hepatocellular
Differential gel-based proteomic approach for cancer biomarker discovery using human plasma.
Carcinoma, Hepatocellular
Direct stimulation of immediate-early genes by intranuclear insulin in trypsin-treated H35 hepatoma cells.
Carcinoma, Hepatocellular
Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
Carcinoma, Hepatocellular
Effect of trypsin on morphological integrity and some functional activities of mitochondria from normal liver and AH-130 Yoshida ascites hepatoma.
Carcinoma, Hepatocellular
Effect of trypsin on the cell surface proteins of hepatoma tissue culture cells. Characterization of a carbohydrate-rich glycopeptide released from a calcium binding membrane glycoprotein.
Carcinoma, Hepatocellular
Enhanced proliferation of human hepatoma cells by PAR-2 agonists via the ERK/AP-1 pathway.
Carcinoma, Hepatocellular
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Carcinoma, Hepatocellular
Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.
Carcinoma, Hepatocellular
High permissivity of human HepG2 hepatoma cells for influenza viruses.
Carcinoma, Hepatocellular
Identification of Chromosomal Aberrations by Using Trypsin G-banding in Hepatocellular Carcinoma Patients (HCC) in Tamil Nadu, India.
Carcinoma, Hepatocellular
Immunoradioautographic study of alpha-fetoprotein in hepatoma cells.
Carcinoma, Hepatocellular
Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
Carcinoma, Hepatocellular
Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor.
Carcinoma, Hepatocellular
Insulin receptor regulation in minimal deviation hepatoma cell line.
Carcinoma, Hepatocellular
Necrotic Response to Low Pathogenic H9N2 Influenza Virus in Chicken Hepatoma Cells.
Carcinoma, Hepatocellular
Overexpression of tumor-associated trypsin inhibitor (SPINK1/TATI) in hepatitis C-associated hepatocellular carcinoma: potential implications for viral hepatocarcinogenesis.
Carcinoma, Hepatocellular
Overexpression of tumour-associated trypsin inhibitor (TATI) enhances tumour growth and is associated with portal vein invasion, early recurrence and a stage-independent prognostic factor of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma.
Carcinoma, Hepatocellular
Preparation of single cell suspensions from hepatoma cells in culture.
Carcinoma, Hepatocellular
Prognostic significance of tumor-associated trypsin inhibitor (TATI) and human chorionic gonadotropin-? (hCG?) in patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
Carcinoma, Hepatocellular
Release of glycopeptides and mucopolysaccharides from ascites hepatoma cells by tryptic treatment.
Carcinoma, Hepatocellular
Secretion of insulin-like growth factor binding protein-1 from individual hepatocytes.
Carcinoma, Hepatocellular
Serum trypsin inhibitory capacity and alpha 1-antitrypsin levels in liver cirrhosis and hepatoma.
Carcinoma, Hepatocellular
Specific expression of the pancreatic-secretory-trypsin-inhibitor (PSTI) gene in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
Carcinoma, Hepatocellular
[Effect of ERK/AP-1 signaling pathway on proliferation of hepatoma cells induced by PAR-2 agonists]
Carcinoma, Hepatocellular
[Enzymatic activity of cathepsin B, cathepsin B and L, plasmin, trypsin and collagenase in hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Growth of Zajdela ascites hepatoma cells in vivo following treatment with trypsin and pronase in vitro]
Carcinoma, Lewis Lung
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Carcinoma, Lewis Lung
Expression of urokinase and urinary trypsin inhibitor in metastatic and non-metastatic murine Lewis lung carcinoma cells.
Carcinoma, Lewis Lung
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Carcinoma, Lewis Lung
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Carcinoma, Lobular
Elastosis in breast carcinoma: II. Association of protease inhibitors with immature elastic fibres.
Carcinoma, Ovarian Epithelial
Comparison of tumor-associated trypsin inhibitor (TATI) with CA125 as a marker for diagnosis and monitoring of epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Elevated serum insulin-like growth factor-binding protein 2 (IGFBP-2) and decreased IGFBP-3 in epithelial ovarian cancer: correlation with cancer antigen 125 and tumor-associated trypsin inhibitor.
Carcinoma, Ovarian Epithelial
Expression of trypsinogen-1, trypsinogen-2, and tumor-associated trypsin inhibitor in ovarian cancer: prognostic study on tissue and serum.
Carcinoma, Ovarian Epithelial
Pre-operative serum level of tumour-associated trypsin inhibitor and residual tumour size as prognostic indicators in Stage III epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Tumor-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA125) in patients with epithelial ovarian cancer.
Carcinoma, Renal Cell
Characterization and purification of a guanidinobenzoatase: a possible marker of human renal carcinoma.
Carcinoma, Renal Cell
Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
Carcinoma, Renal Cell
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Carcinoma, Squamous Cell
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Carcinoma, Squamous Cell
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Carcinoma, Squamous Cell
Chemotherapy as initial treatment for cervical carcinoma: clinical and tumor marker response.
Carcinoma, Squamous Cell
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Carcinoma, Squamous Cell
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma.
Carcinoma, Squamous Cell
Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
Carcinoma, Squamous Cell
Evaluation of Mannosidase and Trypsin Enzymes Effects on Biofilm Production of Pseudomonas aeruginosa Isolated from Burn Wound Infections.
Carcinoma, Squamous Cell
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Carcinoma, Squamous Cell
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Carcinoma, Squamous Cell
Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma.
Carcinoma, Squamous Cell
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Carcinoma, Squamous Cell
Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
Carcinoma, Squamous Cell
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Carcinoma, Squamous Cell
Trypsin-2 Enhances Carcinoma Invasion by Processing Tight Junctions and Activating ProMT1-MMP.
Carcinoma, Transitional Cell
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Carcinoma, Transitional Cell
Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder.
Cardiomyopathies
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Cardiomyopathies
[High level of immunoreactive circulating trypsin in primary myocardiopathy in cystic fibrosis]
Cardiomyopathy, Dilated
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Cardiotoxicity
A lethal cardiotoxic-cytotoxic protein from the Indian monocellate cobra (Naja kaouthia) venom.
Cardiovascular Diseases
MRM-based, multiplexed, absolute quantitation of 45 proteins in human plasma.
Cardiovascular Diseases
The Morama Bean (Tylosema esculentum) A Potential Crop for Southern Africa.
carnitine o-palmitoyltransferase deficiency
Limited trypsin proteolysis renders carnitine palmitoyltransferase insensitive to inhibition by malonyl-CoA in patients with muscle carnitine palmitoyltransferase deficiency.
Cataract
Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract.
Cataract
Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin.
Cataract
Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction.
Cataract
NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility.
Cataract
Proteases and protease inhibitory activities in normal mammalian lenses and human cataractous lenses.
Cataract
The effects of aging and cataract formation on the trypsin inhibitor activity of human lens.
Cataract
The human anterior lens capsule--an attempted chemical debridement of epithelial cells by ethylenediaminetetracetic acid (EDTA) and trypsin.
Cataract
[Studies on the effect of the pancreatic enzymes alpha-chymotrypsin and trypsin on the lens capsule in cataract extraction with enzymatic zonulysis.]
Celiac Disease
Plasma cholecystokinin and pancreatic enzyme secretion in patients with coeliac sprue.
Celiac Disease
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Celiac Disease
Time-related enzyme concentrations in duodenal aspirates after ingestion of a test meal.
Celiac Disease
Trypsin cleavage sites are highly unlikely to occur in celiac-causing restricted epitopes.
Cerebrovascular Disorders
[Effect of trypsin inhibitor on cerebral edema associated with cerebrovascular diseases]
Chagas Disease
Leishmania donovani donovani antigens recognized by kala-azar patient sera and identification of cross-reacting antigens to Chagas' disease.
Cholangiocarcinoma
Enhanced detection of cholangiocarcinoma with serum trypsinogen-2 in patients with severe bile duct strictures.
Cholangiocarcinoma
Proteinase-activated receptor 2 (PAR(2)) in cholangiocarcinoma (CCA) cells: effects on signaling and cellular level.
Cholangiocarcinoma
Relationship between pancreatic secretory trypsin inhibitor and early recurrence of intrahepatic cholangiocarcinoma following surgical resection.
Cholangiocarcinoma
Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2.
Cholangitis, Sclerosing
The pancreas in primary biliary cirrhosis and primary sclerosing cholangitis.
Cholecystitis
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
Cholecystitis, Acute
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of oddi and could make EPT a logical procedure.
Cholecystitis, Acute
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of Oddi and could make EPT a logical procedure.
Cholecystitis, Acute
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Cholecystitis, Acute
[Arginine esterase activity and the trypsin inhibitor level in the blood serum in different forms of acute cholecystitis]
Choledochal Cyst
Western blotting in the diagnosis of duodenal-biliary and pancreaticobiliary refluxes in biliary diseases.
Cholelithiasis
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of oddi and could make EPT a logical procedure.
Cholelithiasis
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
Cholera
A procedure for the isolation of primary cultures of melanocytes from newborn and adult human skin.
Cholera
Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions.
Cholera
Correlation between macrophages and their membrane fraction. Cytocidal activities on neoplastic cells.
Cholera
Differences in growth requirements between epithelial and stromal cells derived from rat ventral prostate in serum-free primary culture.
Cholera
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Cholera
Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation.
Cholera
Mesocestoides lineatus: trypsin induced development to adult mediated by Ca2+ and protein kinase C.
Cholera
Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells.
Cholera
Structure of the ceramide moiety of GM1 ganglioside determines its occurrence in different detergent-resistant membrane domains in HL-60 cells.
Cholera
The biological activity of bovine and human thyrotropin is differently affected by trypsin treatment of human thyroid cells: thyroid-stimulating antibody is related to human thyrotropin.
Cholera
[Differentiation of cholera Vibrio from El Tor vibrios by a trypsin broth medium. II. Heat-sterilized trypsin broth]
Cholera
[Trypsin broth as a medium for cholera and El Tor vibrio. 1. Modification of the original formula]
Cholestasis
Effect of bile duct obstruction on pancreatic enzyme secretion and intestinal proteolytic enzyme activity in the rat.
Cholestasis
Mechanisms for the pancreatic oncogenic effects of the peroxisome proliferator Wyeth-14,643.
Cholestasis, Extrahepatic
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
Chondrosarcoma
An amino acid sequence common to both cartilage proteoglycan and link protein.
Chondrosarcoma
Characterization of binding properties of urinary trypsin inhibitor to cell-associated binding sites on human chondrosarcoma cell line HCS-2/8.
Chondrosarcoma
Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.
Chondrosarcoma
Light and electron microscopic studies on the localization of hyaluronic acid in developing rat cerebellum.
Chondrosarcoma
Monoclonal antibodies as probes for determining the microheterogeneity of the link proteins of cartilage proteoglycan.
Choriocarcinoma
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Choriocarcinoma
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Choriocarcinoma
[Bovine endothelial cell destruction by choriocarcinoma cell line (SMT-cc1) (inhibition of destruction by urinary trypsin inhibitor)]
Chronic Periodontitis
Phenotypic identification of Porphyromonas gingivalis validated with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Chronic Periodontitis
[Clinico-roentgenological assessment of the treatment of chronic periodontitis by trypsin electrophoresis of root canals]
Citrullinemia
An adult-onset case of argininosuccinate synthetase deficiency presenting with atypical citrullinemia.
Citrullinemia
High serum pancreatic secretory trypsin inhibitor before onset of type II citrullinemia.
Citrullinemia
Pancreatic secretory trypsin inhibitor as a diagnostic marker for adult-onset type II citrullinemia.
Citrullinemia
Pancreatic secretory trypsin inhibitor gene is highly expressed in the liver of adult-onset type II citrullinemia.
Cleft Palate
In vitro manipulation of cleft palate connective tissue: setting the bases of a proposed new treatment.
coagulation factor xiia deficiency
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Coccidiosis
[Changes in the intestinal activity of trypsin through bivalent cations and their determination by means of appendix coccidiosis]
Coinfection
Avian influenza virus h3 hemagglutinin may enable high fitness of novel human virus reassortants.
Colitis
Pancreatic and granulocytic endoproteases in faecal extracts from patients with active ulcerative colitis.
Colitis
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Colitis
The beneficial effect of combination therapy with sulfasalazine and valsartan in the treatment of ulcerative colitis.
Colitis
Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis.
Colitis
Wheat Consumption Aggravates Colitis in Mice via Amylase Trypsin Inhibitor-mediated Dysbiosis.
Colitis
[Activity of trypsin, its inhibitors and antiinhibitors in blood serum of patients with chronic colitis and enterocolitis]
Colitis, Ulcerative
A trial of intravenous trypsin in the treatment of chronic ulcerative colitis.
Colitis, Ulcerative
Colonic proteinases: increased activity in patients with ulcerative colitis.
Colitis, Ulcerative
Immunoreactive pancreatic secretory trypsin inhibitor in sera from patients with acute ulcerative colitis.
Colitis, Ulcerative
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Colitis, Ulcerative
Pancreatic and granulocytic endoproteases in faecal extracts from patients with active ulcerative colitis.
Colitis, Ulcerative
Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa.
Colonic Diseases
[Trypsin and chymotrypsin in the differential diagnosis of inflammatory colonic diseases]
Colonic Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Colonic Neoplasms
ATP requirement for induced tight junction formation in HT 29 adenocarcinoma cells.
Colonic Neoplasms
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Colonic Neoplasms
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Colonic Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Colonic Neoplasms
Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
Colonic Neoplasms
Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2.
Colonic Neoplasms
Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins.
Colonic Neoplasms
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Colonic Neoplasms
Pancreatic trypsinogen I expression during cell growth and differentiation of two human colon carcinoma cells.
Colonic Neoplasms
Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
Colonic Neoplasms
Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors.
Colonic Neoplasms
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.
Colorectal Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Colorectal Neoplasms
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Colorectal Neoplasms
Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Colorectal Neoplasms
Expression of pancreatic secretory trypsin inhibitor (PSTI) in colorectal cancer.
Colorectal Neoplasms
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Colorectal Neoplasms
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Colorectal Neoplasms
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
Colorectal Neoplasms
New intracellular and molecular aspects in pathophysiology of colorectal cancer.
Colorectal Neoplasms
Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
Colorectal Neoplasms
Serum proteolytic activities and antiproteases in human colorectal carcinoma.
Colorectal Neoplasms
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
Colorectal Neoplasms
The silk of Plodia interpunctella as a potential biomaterial and its cytotoxic effect on cancer cells.
Colorectal Neoplasms
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Colorectal Neoplasms
Tumor-associated trypsin inhibitor (TATI) in patients with colorectal carcinoma. A critical comparison with CEA.
Colorectal Neoplasms
Tumor-derived suppressor factors (TDSFs) in normal and neoplastic colon and rectum.
Colorectal Neoplasms
Tumour-associated trypsin inhibitor (TATI) in patients with colorectal cancer: a comparison with CEA, CA 50 and CA 242.
Colorectal Neoplasms
Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
Colorectal Neoplasms
[Expression of trypsin and cancer proliferation in colorectal neoplasms]
Common Cold
Does Trypsin Oral Spray (Viruprotect®/ColdZyme®) Protect against COVID-19 and Common Colds or Induce Mutation? Caveats in Medical Device Regulations in the European Union.
Connective Tissue Diseases
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases.
Connective Tissue Diseases
Effect of enzyme treatment of Chrithidia luciliae on the reactivity of its kinetoplast with anti-DNA sera.
Contracture
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Contracture
Neuromuscular actions of sodium selenite on chick biventer cervicis nerve-muscle preparation.
Contracture
Studies on the contracture inducing action of triphenyltin in the mouse diaphragm.
Corneal Diseases
Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease.
Corneal Dystrophies, Hereditary
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
Corneal Injuries
[Experimental studies on corneal injuries by alpha-chymotrypsin and trypsin.]
Coronary Artery Disease
Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus.
Coronavirus Infections
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.
Cough
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
COVID-19
Does Trypsin Oral Spray (Viruprotect®/ColdZyme®) Protect against COVID-19 and Common Colds or Induce Mutation? Caveats in Medical Device Regulations in the European Union.
COVID-19
Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Therapeutic Antibody Cocktail REGEN-COV Concentrations in COVID-19 Patient Serum.
Cowpox
The effect of trypsin on the formation of virus-specific surface antigen in cowpox virus-infected cells.
Crohn Disease
Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.
Crohn Disease
Concentrations of pancreatic secretory trypsin inhibitor (PSTI), acute phase proteins, and neopterin in Crohn's disease. Comparison with clinical disease activity and endoscopical findings.
Crohn Disease
Impaired luminal processing of human defensin-5 in Crohn's disease: persistence in a complex with chymotrypsinogen and trypsin.
Crohn Disease
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Crohn Disease
Levels of trypsin and alpha-chymotrypsin in feces from patients with Crohn's disease.
Crohn Disease
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Cystadenoma
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Cystic Fibrosis
A high prevalence of genetic polymorphisms in idiopathic and alcohol-associated chronic pancreatitis patients in Ireland.
Cystic Fibrosis
Abnormal breakdown of alpha2-macroglobulin-trypsin complex in cystic fibrosis.
Cystic Fibrosis
Abnormalities of circulating immunoreactive pancreatic anionic trypsinogen in cystic fibrosis: an assay artifact due to cross-reacting serum antibodies.
Cystic Fibrosis
Activation of normal and cystic fibrosis Cl- channels by voltage, temperature, and trypsin.
Cystic Fibrosis
Age-related alterations in immunoreactive pancreatic lipase and cationic trypsinogen in young children with cystic fibrosis.
Cystic Fibrosis
Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency.
Cystic Fibrosis
Amniotic immunoreactive trypsin in pregnancies with normal and pathological outcomes.
Cystic Fibrosis
An evaluation of an enzyme immunoassay method for immunoreactive trypsin in dried blood spots.
Cystic Fibrosis
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Cystic Fibrosis
Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis.
Cystic Fibrosis
Antibodies cross-reacting with porcine and human trypsin in cystic fibrosis.
Cystic Fibrosis
Assay of serum immunoreactive trypsin in dried blood spots and the early detection of cystic fibrosis.
Cystic Fibrosis
Association Analyses of Genetic Polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR With Chronic Alcoholic Pancreatitis in Japan.
Cystic Fibrosis
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Cystic Fibrosis
Behaviour of serum immunoreactive trypsin after serum activation by enterokinase in normal and cystic fibrosis patients. Evidence of a trypsin-alpha 1-proteinase inhibitor complex in some cystic fibrosis patients.
Cystic Fibrosis
Carboxypeptidase A activity of cultured skin fibroblasts and relationship to cystic fibrosis.
Cystic Fibrosis
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
Cystic Fibrosis
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Cystic Fibrosis
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Cystic Fibrosis
Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas.
Cystic Fibrosis
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Cystic Fibrosis
Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Are Associated with Chronic Pancreatitis in Patients without Cystic Fibrosis.
Cystic Fibrosis
Comparison between purified alpha2-macroglobulin preparations from normal controls and patients with cystic fibrosis. Kinetic and structural properties of the complex with bovine trypsin.
Cystic Fibrosis
Comparison of the diagnostic value of serum pancreatic isoamylase and immunoreactive trypsin measurement in patients with cystic fibrosis.
Cystic Fibrosis
Comparison of two different protocols of neonatal screening for cystic fibrosis.
Cystic Fibrosis
Competition for trypsin binding between alpha 2-macroglobulin and antitrypsin antibodies in cystic fibrosis.
Cystic Fibrosis
Comprehensive screening for PRSS1, SPINK1, CFTR, CTRC and CLDN2 gene mutations in Chinese paediatric patients with idiopathic chronic pancreatitis: a cohort study.
Cystic Fibrosis
Concentrations of trypsin, elastase and carbohydrate antigen CA 19-9 in serum of cystic fibrosis patients.
Cystic Fibrosis
Conclusions from a pilot immunoreactive trypsin newborn screen for cystic fibrosis.
Cystic Fibrosis
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Cystic Fibrosis
Cystic fibrosis identified by neonatal screening: incidence, genotype, and early natural history.
Cystic Fibrosis
Cystic fibrosis newborn screening: outcome of infants with normal sweat tests.
Cystic Fibrosis
Cystic fibrosis newborn screening: the importance of bloodspot sample quality.
Cystic Fibrosis
Cystic fibrosis screening by dried blood spot trypsin assay: results in 75,000 newborn infants.
Cystic Fibrosis
Cystic fibrosis screening in neonates--measurement of immunoreactive trypsin and direct genotype analysis for delta F508 mutation.
Cystic Fibrosis
Decreased immunoreactive trypsin levels in sera from cystic fibrosis patients.
Cystic Fibrosis
Deficiency of arginine esterase in cystic fibrosis of the pancreas: demonstration of the proteolytic nature of the activity.
Cystic Fibrosis
Determination and characterization of immunoreactive trypsin in amniotic fluid from normal and cystic fibrosis fetuses.
Cystic Fibrosis
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.
Cystic Fibrosis
Development of a screening system for cystic fibrosis: meconium or blood spot trypsin assay or both?
Cystic Fibrosis
Diagnosis of cystic fibrosis, by assay of immuno-reactive trypsin in a newborn infant with jejuno-ileal atresias.
Cystic Fibrosis
Differences in immunoreactive trypsin values between type of feeding and ethnicity in neonatal cystic fibrosis screening: a cross-sectional study.
Cystic Fibrosis
Does cystic fibrosis neonatal screening detect atypical CF forms? Extended genetic characterization and 4-year clinical follow-up.
Cystic Fibrosis
Dual core quantum dots for highly quantitative ratiometric detection of trypsin activity in cystic fibrosis patients.
Cystic Fibrosis
Effect of pancreozymin and secretin on intraluminal enterokinase, trypsin, and chymotrypsin activities of cystic fibrosis and control children.
Cystic Fibrosis
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Cystic Fibrosis
Evidence that hereditary pancreatitis is genetically heterogeneous disorder.
Cystic Fibrosis
Genetic counseling for hereditary pancreatitis--the role of molecular genetics testing for the cationic trypsinogen gene, cystic fibrosis and serine protease inhibitor Kazal type 1.
Cystic Fibrosis
Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.
Cystic Fibrosis
Genetic factors in chronic pancreatitis; implications for diagnosis, management and prognosis.
Cystic Fibrosis
Germline mutations and gene polymorphism associated with human pancreatitis.
Cystic Fibrosis
Germline mutations in CFTR and PSTI genes in chronic pancreatitis patients.
Cystic Fibrosis
Hereditary pancreatitis in Japan: a review of pancreatitis-associated gene mutations.
Cystic Fibrosis
History of Newborn Screening for Cystic Fibrosis-The Early Years.
Cystic Fibrosis
Identification of a Novel Frame-Shift Mutation in PRSS1 Gene in Han Patients with Autoimmune Pancreatitis.
Cystic Fibrosis
Identification of patients with genetic risk factors of pancreatitis: impact on treatment and cancer prevention.
Cystic Fibrosis
Idiopathic pancreatitis related to CFTR: complex inheritance and identification of a modifier gene.
Cystic Fibrosis
Immaturity of the myenteric plexus is the aetiology of meconium ileus without mucoviscidosis: a histopathologic study.
Cystic Fibrosis
Immunoreactive trypsin levels in young cystic fibrosis patients and in other sick children.
Cystic Fibrosis
Immunoreactive trypsin on dried-blood spots as a possible neonatal test for cystic fibrosis. (I. Evaluation of the method and preliminary field trial).
Cystic Fibrosis
Immunoreactive trypsin, chymotrypsin, and pancreatic secretory trypsin inhibitor in cord blood from infants with cystic fibrosis.
Cystic Fibrosis
Immunoreactive trypsin/DNA newborn screening for cystic fibrosis: should the R117H variant be included in CFTR mutation panels?
Cystic Fibrosis
Indirect parameters of pancreatic function in cystic fibrosis (CF) during a controlled double-blind trial of pancreatic supplementation.
Cystic Fibrosis
Laboratory quality control issues related to screening newborns for cystic fibrosis using immunoreactive trypsin.
Cystic Fibrosis
Levels and molecular forms of immunoreactive trypsin and chymotrypsin in amniotic fluids from normal and cystic fibrosis fetus: evidence for a lack of activation of proteolytic zymogens in cystic fibrosis fetus.
Cystic Fibrosis
Longitudinal evaluation of serum trypsinogen measurement in pancreatic-insufficient and pancreatic-sufficient patients with cystic fibrosis.
Cystic Fibrosis
Molecular understanding of chronic pancreatitis: a perspective on the future.
Cystic Fibrosis
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion.
Cystic Fibrosis
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Cystic Fibrosis
Mutation analysis of the cystic fibrosis and cationic trypsinogen genes in patients with alcohol-related pancreatitis.
Cystic Fibrosis
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Cystic Fibrosis
Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis.
Cystic Fibrosis
Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis.
Cystic Fibrosis
Neonatal cystic fibrosis screening: Analysis and differences in immunoreactive trypsin levels in newborns with a positive screen.
Cystic Fibrosis
Neonatal infection does not affect the immunoreactive trypsinogen screening test for cystic fibrosis.
Cystic Fibrosis
Neonatal screening for cystic fibrosis by dried blood spot trypsin assay. Results in 47 127 newborn infants from a homogeneous population.
Cystic Fibrosis
Neonatal screening for cystic fibrosis in the Trent region (UK): two-stage immunoreactive trypsin screening compared with a three-stage protocol with DNA analysis as an intermediate step.
Cystic Fibrosis
Neonatal screening for cystic fibrosis in Wales and the West Midlands: 1. Evaluation of immunoreactive trypsin test.
Cystic Fibrosis
Neonatal screening for cystic fibrosis in Wales and the West Midlands: clinical assessment after five years of screening.
Cystic Fibrosis
Neonatal screening for cystic fibrosis, using immunoreactive trypsin assay in dried blood spots.
Cystic Fibrosis
Newborn screening strategy for cystic fibrosis: a field study in an area with high allelic heterogeneity.
Cystic Fibrosis
Pancreatic fluid secretion and protein hyperconcentration in cystic fibrosis.
Cystic Fibrosis
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Cystic Fibrosis
Pericellular glycoconjugates of cultured fibroblasts from control and cystic fibrosis patients.
Cystic Fibrosis
Plasma immunoreactive cationic trypsin(ogen) pattern in reserpinized rat model of cystic fibrosis. Resemblance to humans.
Cystic Fibrosis
Plasma immunoreactive pancreatic cationic trypsinogen in cystic fibrosis: a sensitive indicator of exocrine pancreatic dysfunction.
Cystic Fibrosis
Prognosis in cystic fibrosis treated with continuous flucloxacillin from the neonatal period.
Cystic Fibrosis
PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis.
Cystic Fibrosis
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
Cystic Fibrosis
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Cystic Fibrosis
Secretin pancreozymin stimulation test and confirmation of the diagnosis of cystic fibrosis.
Cystic Fibrosis
Sensitive trypsin assay for dried-blood specimens as a screening procedure for early detection of cystic fibrosis.
Cystic Fibrosis
Serum immuno reactive trypsin and pancreatic isoamylase in older patients with cystic fibrosis.
Cystic Fibrosis
Serum immunoglobulin G directed against porcine trypsin in pancreatic insufficient cystic fibrosis patients receiving pancreatic enzyme supplements.
Cystic Fibrosis
Serum immunoglobulin G directed against porcine trypsin in the serum of cystic fibrosis children receiving porcine pancreatic enzyme supplements.
Cystic Fibrosis
Serum immunoreactive cationic trypsinogen: a useful indicator of severe exocrine dysfunction in the paediatric patient without cystic fibrosis.
Cystic Fibrosis
Serum immunoreactive pancreatic lipase and cationic trypsinogen for the assessment of exocrine pancreatic function in older patients with cystic fibrosis.
Cystic Fibrosis
Silica nanoparticle-based microfluidic immunosensor with laser-induced fluorescence detection for the quantification of immunoreactive trypsin.
Cystic Fibrosis
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
Cystic Fibrosis
Studies on cystic fibrosis of the pancreas; role of various diluents and the dilution factor in the interpretation of the x-ray film test for fecal trypsin.
Cystic Fibrosis
Targeted Gene Next-Generation Sequencing in Chinese Children with Chronic Pancreatitis and Acute Recurrent Pancreatitis.
Cystic Fibrosis
The application of PCR amplification and the polymorphic marker KM.19 to dried blood spots: comparison with deletion 508 for the confirmation of the neonatal screening test for cystic fibrosis.
Cystic Fibrosis
The neonatal detection of cystic fibrosis by measurement of immunoreactive trypsin in blood.
Cystic Fibrosis
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
Cystic Fibrosis
The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis.
Cystic Fibrosis
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
Cystic Fibrosis
Titrimetric measurements of fecal trypsin and chymotrypsin in cystic fibrosis with pancreatic exocrine insufficiency.
Cystic Fibrosis
Trypsin activity in stool and duodenal aspirate of neonates for differential diagnosis of intestinal obstruction.
Cystic Fibrosis
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Cystic Fibrosis
[A new strategy of neonatal screening for cystic fibrosis. The association of immunoreactive trypsin and molecular biology in dried blood]
Cystic Fibrosis
[Determination of trypsin in dried blood for neonatal detection of cystic fibrosis]
Cystic Fibrosis
[Early detection of mucoviscidosis patients using trypsin RIA in dried blood stains]
Cystic Fibrosis
[Genetic mutations as a cause of acute recurrent pancreatitis in children - case report and literature review].
Cystic Fibrosis
[High level of immunoreactive circulating trypsin in primary myocardiopathy in cystic fibrosis]
Cystic Fibrosis
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Cystic Fibrosis
[Interest in pediatrics in the value of trypsin by the radioimmunologic method]
Cystic Fibrosis
[Mucoviscidosis screening with immunoreactive trypsin. Initial experiences in Austria]
Cystic Fibrosis
[Neonatal cystic fibrosis screening program in the state of Paraná: evaluation 30 months after implementation]
Cystic Fibrosis
[Neonatal cystic fibrosis screening: Analysis and differences in immunoreactive trypsin levels in newborns with a positive screen].
Cystic Fibrosis
[Neonatal screening of mucoviscidosis using radioimmunologic levels of trypsin in dried blood eluates]
Cystic Fibrosis
[Radioimmunoassay of trypsin in dried blood. Importance for the neonatal detection of cystic fibrosis (author's transl)]
Cystic Fibrosis
[Regional mucoviscidosis screening using immunoreactive trypsin in umbilical cord blood]
Cystic Fibrosis
[Screening of newborn infants for cystic fibrosis. A combined analysis of immunoreactive trypsin and delta F508 mutation--a screening without false positive results]
Cystic Fibrosis
[Systematic neonatal screening for mucoviscidosis using an immunoreactive trypsin blood assay. Evaluation of 80,000 tests]
Cystic Fibrosis
[Trypsin in the meconium in healthy subjects and subjects with cystic fibrosis]
Cystitis
Involvement of bradykinin in trypsin-induced urinary bladder contraction in cyclophosphamide-treated rats.
Cystitis
[Study on infectious mechanism of type 1 fimbriated Escherichia coli in experimental cystitis of mice]
Cysts
A freeze-fracture study of the host cell-parasite interface during and after invasion of cultured cells by cystozoites of Sarcocystis muris.
Cysts
A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells.
Cysts
A serine proteinase in the penetration glands of the hexacanths of Hymenolepis diminuta (Cestoda, Cyclophyllidea).
Cysts
Biochemical and enzymatic characterization of decapsulated cysts and nauplii of the brine shrimp Artemia at different developmental stages.
Cysts
Cancer-associated antigen CA 195 in patients with mucinous ovarian tumours: a comparative analysis with CEA, TATI and CA 125 in serum specimens and cyst fluids.
Cysts
Characterization of phospholipase A2 activity in aspirates of human pancreatic pseudocysts after isolation by reversed-phase high performance liquid chromatography.
Cysts
Cyst fluid tumor-associated trypsin inhibitor may be helpful in the differentiation of cystic pancreatic lesions.
Cysts
Cystoisospora canis (Apicomplexa: Sarcocystidae): Development of monozoic tissue cysts in human cells, demonstration of egress of zoites from tissue cysts, and demonstration of repeat monozoic tissue cyst formation by zoites.
Cysts
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Cysts
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Cysts
Effect of emetine hydrochloride on cysts of amoebae in presence of trypsin and lysozyme.
Cysts
Enhanced transgenic plant resistance to nematodes by dual proteinase inhibitor constructs.
Cysts
Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
Cysts
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Cysts
Immunodetection of Pneumocystis carinii in bronchoalveolar lavage specimens compared with methenamine silver stain.
Cysts
In vitro excystment of the metacercariae of Cloacitrema michiganensis (Trematoda: Philophthalmidae).
Cysts
In vivo and in vitro excystation of Zygocotyle lunata (Trematoda) metacercariae and histochemical observations on the cyst.
Cysts
Observations on the life-cycle of the strigeoid trematode, Apatemon (Apatemon) gracilis (Rudolphi, 1819) Szidat, 1928.
Cysts
Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
Cysts
Preparation and applicability of Sarcocystis cruzi antigens and their anti-S. cruzi rabbit sera for serodiagnosis of bovine sarcocystosis.
Cysts
Sporamin-mediated resistance to beet cyst nematodes (Heterodera schachtii Schm.) is dependent on trypsin inhibitory activity in sugar beet (Beta vulgaris L.) hairy roots.
Cysts
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Cysts
Ultrastructural and molecular characterization of Sarcocystis isolated from camel (Camelus dromedarius) in Iran.
Cysts
Western blotting in the diagnosis of duodenal-biliary and pancreaticobiliary refluxes in biliary diseases.
Cysts
[Isolation of germinal cells from the secondary cysts of Echinococcus granulosus harbored in mice]
Cytomegalovirus Retinitis
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
Deafness
Familial idiopathic hypoparathyroidism, sensorineural deafness and renal dysplasia.
Deafness
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Dehydration
An immunocytochemical investigation of trypsin secretion in the midgut of the stablefly, Stomoxys calcitrans.
Dehydration
Comparative evaluation of bioactivity of crystalline trypsin for drying by Fourier-transformed infrared spectroscopy.
Dehydration
Impaired drinking response in histamine H3 receptor knockout mice following dehydration or angiotensin-II challenge.
Dehydration
NisP is related to nisin precursor processing and possibly to immunity in Lactococcus lactis.
Dehydration
[The content of abscisic acid and the activities of proteinases and trypsin inhibitory proteins in the germinating seed of common beans under conditions of water stress]
Dehydration
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
Dementia
Amyloid beta protein precursors with kunitz-type inhibitor domains and acetylcholinesterase in cerebrospinal fluid from patients with dementia of the Alzheimer type.
Dementia
Trypsin inhibition: a potential cause of cobalamin deficiency common to the pathogenesis of Alzheimer-type dementia and AIDS dementia complex?
Demyelinating Diseases
An electrophysiological and histological study of trypsin induced demyelination.
Demyelinating Diseases
Cerebrospinal fluid of HTLV-1 associated myelopathy patients induces axonal sproutings and Schwann cell proliferation in the rat sciatic nerve.
Demyelinating Diseases
Fluidity of the myelin sheath in the peripheral nerves of diabetic rats.
Dengue
A propeptide-independent protease from Tannerella sp.6_1_58FAA_CT1 displays trypsin-like specificity.
Dengue
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Dengue
Evidence for two mechanisms of dengue virus infection of adherent human monocytes: trypsin-sensitive virus receptors and trypsin-resistant immune complex receptors.
Dengue
Internalization and propagation of the dengue virus in human hepatoma (HepG2) cells.
Dengue
Organization of flaviviral replicase proteins in virus-induced membranes: a role for NS1' in Japanese encephalitis virus RNA synthesis.
Dengue
The sensitivity of cell-associated dengue virus proteins to trypsin and the detection of trypsin-resistant fragments of the nonstructural glycoprotein NS1.
Dental Caries
Characterization of multiply phosphorylated peptides selectively precipitated from a pancreatic casein digest.
Dental Caries
[On the use of enzyme preparations in the therapy of dental caries with special reference to trypsin]
Dental Plaque
Fibronectin fragmentation induced by dental plaque and Bacteroides gingivalis.
Dental Plaque
[Cooperation of antigens, immunoglobulins, complement and antimicrobial enzymes in the regulation of blood granulocyte locomotion]
Dermatitis
Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis.
Dermatitis, Atopic
Exonic mutations associated with atopic dermatitis disrupt lympho-epithelial Kazal-type related inhibitor action and enhance its degradation.
Dermatitis, Atopic
Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
Dermatitis, Contact
Contact sensitivity in the mouse. V. The role of macrophage cytophilic antibody in passive transfer and the effect of trypsin and anti-gamma globulin serum.
Dermatitis, Phototoxic
Enhanced susceptibility to HPD-sensitized phototoxicity and correlated resistance to trypsin detachment in SV40 transformed IMR-90 cells.
Dermatomycoses
Comparison of trypsin treatment method and standard laboratory technique for diagnosis of dermatomycosis.
Diabetes Mellitus
Absence of association between SPINK1 trypsin inhibitor mutations and Type 1 or 2 diabetes mellitus in India and Germany.
Diabetes Mellitus
Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis.
Diabetes Mellitus
Non enzymatic glycosylation of alpha-1-proteinase inhibitor of human plasma.
Diabetes Mellitus
Plasma inactive renin in patients with diabetes mellitus: effects of standing and the relation to serum protease inhibitor.
Diabetes Mellitus
Trypsin in the treatment of local complications of peripheral vascular disease in diabetes mellitus.
Diabetes Mellitus
[Activity of serum and lymphocyte serine proteases of patients with diabetes mellitus and the possibility of using protease blockers in combined therapy]
Diabetes Mellitus
[Clinical significance of urinary excretion of pancreatic secretory trypsin inhibitor in the diagnosis of diabetes mellitus]
Diabetes Mellitus
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
Diabetes Mellitus
[Use of pancreozymin for detection of pancreatic enzyme-secreting insufficiency in diabetic patients and selection of methods of treatment]
Diabetes Mellitus, Experimental
[Characteristics of the course of alloxan diabetes in rats with various methods of isografting the islands of Langerhans]
Diabetes Mellitus, Type 1
Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined.
Diabetes Mellitus, Type 1
Distinct antibody specificities to a 64-kD islet cell antigen in type 1 diabetes as revealed by trypsin treatment.
Diabetes Mellitus, Type 1
Exocrine pancreatic function in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Impaired activity of serum alpha-1-antitrypsin in diabetes mellitus.
Diabetes Mellitus, Type 1
Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes.
Diabetes Mellitus, Type 1
Serum trypsin concentration and pancreatic trypsin secretion in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.
Diabetes Mellitus, Type 1
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
Diabetes Mellitus, Type 2
ACID- AND HEAT-STABLE TRYPSIN INHIBITORY PEPTIDE FROM THE VISCERA OF JAPANESE COMMON SQUID (TODARODES PACIFICUS)
Diabetes Mellitus, Type 2
Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Concentration of leukocyte elastase in plasma and polymorphonuclear neutrophil extracts in type 2 diabetes.
Diabetes Mellitus, Type 2
Development of a method for urine bikunin/urinary trypsin inhibitor (UTI) quantitation and structural characterization: Application to type 1 and type 2 diabetes.
Diabetes Mellitus, Type 2
Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes.
Diabetes Mellitus, Type 2
Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis.
Diabetes, Gestational
Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus.
Diabetic Cardiomyopathies
Exposure of cardiomyocytes to angiotensin II induces over-activation of monoamine oxidase type A: Implications in heart failure.
Diabetic Nephropathies
An inhibition of urinary albumin excretion by protease inhibitor in streptozotocin-diabetic rats.
Diabetic Retinopathy
Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy.
Diabetic Retinopathy
TGR5 receptor activation attenuates diabetic retinopathy through suppression of RhoA/ROCK signaling.
Diphtheria
Cloned diphtheria toxin fragment A is expressed from the tox promoter and exported to the periplasm by the SecA apparatus of Escherichia coli K12.
Diphtheria
Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence.
Diphtheria
Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells.
Diphtheria
Isolation and characterization of the cyanogen bromide peptides from the B fragment of diphtheria toxin.
Diphtheria
Isolation and properties of the trypsin-derived ADP-ribosyl peptide from diphtheria toxin-modified yeast elongation factor 2.
Diphtheria
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule.
Diphtheria
[Specificity of antibodies to diphtheria toxin subunits in children with various forms of diphtheria infections]
Diphyllobothriasis
[Inhibitors of proteolytic enzymes in the blood serum of patients with diphyllobothriasis]
Discitis
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Disseminated Intravascular Coagulation
Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.
Disseminated Intravascular Coagulation
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Disseminated Intravascular Coagulation
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor attenuates liver enzyme elevation after liver resection.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
[Pi phenotypes of alpha-1-antitrypsin and antiproteases in meningococcal sepsis]
Donohue Syndrome
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: resistance to proteolytic activation of glycogen synthase by trypsin.
Dry Socket
Alveolitis sicca dolorosa (dry socket): frequency of occurrence and treatment with trypsin.
Duodenal Ulcer
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Duodenal Ulcer
Response to jejunal acidification in man. II. Pancreatic, biliary and gastric responses.
Duodenal Ulcer
The effects of highly selective vagotomy on exocrine pancreatic function in man.
Duodenal Ulcer
[Relationship between the activity of trypsin and trypsin inhibitors in duodenal ulcer]
Duodenogastric Reflux
Clinical relevance of gastroduodenal dysfunction in reflux esophagitis.
Duodenogastric Reflux
Duodenogastric reflux in children: measurement of phospholipids and trypsin in gastric content.
Duodenogastric Reflux
Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro.
Duodenogastric Reflux
Prevention of experimental acute pancreatitis by intraduodenal trypsin inhibitor in rat.
Duodenogastric Reflux
Studies on experimental animals involving surgical procedures and/or nitrosamine treatment related to the etiology of esophageal adenocarcinoma.
Duodenogastric Reflux
Trypsin induces biphasic muscle contraction and relaxation via transient receptor potential vanilloid 1 and neurokinin receptors 1/2 in porcine esophageal body.
Duodenogastric Reflux
[Evaluation of the intensity of the duodenogastric reflux based on the alkaline phosphatase and trypsin activities in the stomach contents]
Dysgerminoma
Elevated serum inhibin and tumor-associated trypsin inhibitor concentrations in a young woman with dysgerminoma of the ovary.
Dyskinesias
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Dyslipidemias
Anti-TNF-? Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-? Induction.
Echinococcosis
[Cure of five hydatid cysts of the lungs by bronchial aspiration; contribution of the adjuvant methods: varidase, trypsin, papain, ultra-sound.]
Eczema
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
Eczema
[Differential diagnostic importance of intracutaneous trypsin injections in endogenous eczema]
Elliptocytosis, Hereditary
Molecular basis of Sp alpha I/65 hereditary elliptocytosis in North Africa: insertion of a TTG triplet between codons 147 and 149 in the alpha-spectrin gene from five unrelated families.
Embolism, Air
[A case of spontaneous pneumothorax with gas embolism in intratracheal trypsin instillation]
Embolism, Air
[Spontaneous pneumothorax with gas embolism during intratracheal administration of trypsin]
Embolism, Fat
The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model.
Empyema, Pleural
[Enzymatic therapy of the pleural empyema with special reference to the results of trypsin therapy.]
Empyema, Pleural
[Irrigation of tuberculous and mixed pleural empyema with trypsin solution (pyosalv).]
Empyema, Pleural
[Therapeutic use of trypsin as a matter of principle in the pleural empyema treatment.]
Encephalitis
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
Encephalitis, Japanese
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Encephalitis, Japanese
Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper.
Encephalitis, Japanese
Organization of flaviviral replicase proteins in virus-induced membranes: a role for NS1' in Japanese encephalitis virus RNA synthesis.
Encephalitis, Tick-Borne
Changing the protease specificity for activation of a flavivirus, tick-borne encephalitis virus.
Encephalitis, Tick-Borne
Immunogenicity of tick-borne encephalitis virus glycoprotein fragments: epitope-specific analysis of the antibody response.
Encephalitis, Tick-Borne
The flavivirus envelope protein E: isolation of a soluble form from tick-borne encephalitis virus and its crystallization.
Encephalitis, Tick-Borne
[Amino acid sequence of various tryptic peptides of the envelope protein of the tick-borne encephalitis virus]
Encephalomyelitis
Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.
Encephalomyelitis
In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans.
Encephalomyelitis
Morphological and biochemical studies on experimental allergic encephalomyelitis in inbred lines of chickens.
Encephalomyelitis
Purification of mouse encephalomyelitis virus (GDVII virus) by means of ether extraction, acetone precipitation, trypsin digestion, and hemagglutination.
Encephalomyelitis
The effect of trypsin on hemagglutination by murine encephalomyelitis virus (GDVII).
Encephalomyelitis
Trypsin-sensitive neutralization site on VP1 of Theiler's murine encephalomyelitis viruses.
Encephalomyelitis, Autoimmune, Experimental
Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.
Encephalomyelitis, Autoimmune, Experimental
Observations on the effects of protease inhibitors on the suppression of experimental allergic encephalomyelitis.
Encephalomyelitis, Enzootic Porcine
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Endometrial Neoplasms
Characterization of a 54 kDa, alpha 1-antitrypsin-like protein isolated from ascitic fluid of an endometrial cancer patient.
Endometrial Neoplasms
Effect of intracavitary radiotherapy on tumor-associated trypsin inhibitor (TATI) in patients with cervical and endometrial cancer.
Endometrial Neoplasms
Monitoring the treatment outcome in endometrial cancer patients by CEA and TATI.
Endometrial Neoplasms
TATI (tumor associated trypsin inhibitor) and cancer antigen 125 (CA 125) in patients with early-stage endometrial cancer.
Endometrial Neoplasms
Tumor-associated trypsin inhibitor in patients with endometrial cancer.
Endometriosis
Protein, progesterone, and protease inhibitors in uterine and peritoneal fluids of women with endometriosis.
Endometriosis
Serum levels of the tumour-associated trypsin inhibitor in patients with endometriosis.
Enteritis
Effect of trypsin inhibitor activity in soya bean on growth performance, protein digestibility and incidence of sub-clinical necrotic enteritis in broiler chicken flocks.
Enteritis
Effects of Clostridium perfringens beta-toxin on the rabbit small intestine and colon.
Enteritis
Effects of diets containing soybean meal on trypsin mRNA expression and activity in Atlantic salmon (Salmo salar L).
Enteritis
Proteinase-activated receptor-2: two potential inflammatory mediators of the gastrointestinal tract in Atlantic salmon.
Enteritis
Significance of beta 2-toxigenic clostridium perfringens infections in animals and their predisposing factors--a review.
Enterocolitis
[Activity of trypsin, its inhibitors and antiinhibitors in blood serum of patients with chronic colitis and enterocolitis]
Enterocolitis
[State of the external secretory function of the pancreas in chronic enterocolitis]
enteropeptidase deficiency
Isolated congenital enterokinase deficiency. Recent findings and review of the literature.
enteropeptidase deficiency
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
enteropeptidase deficiency
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Eosinophilia
Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses.
Epilepsy
A regulatory role for protease-activated receptor-2 in motivational learning in rats.
Equine Infectious Anemia
Physicochemical studies of equine infectious anemia virus. II. Sensitivity of the virus to trypsin.
Equine Infectious Anemia
Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis.
Esophageal Neoplasms
[Responses of cytokines, acute phase proteins, and polymorphonuclear cell elastase to surgical stress in the patients with esophageal cancer]
Esophageal Squamous Cell Carcinoma
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NF??B via an AKT?independent pathway.
Esophagitis
Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells.
Esophagitis
Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis.
Esophagitis
Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats.
Esophagitis
Role of the components of the gastroduodenal contents in experimental acid esophagitis.
Esophagitis
Taurodeoxycholate modulates the effects of pepsin and trypsin in experimental esophagitis.
Esophagitis
Trypsin activity and bile acid concentrations in the esophagus after distal gastrectomy.
Esophagitis, Peptic
Alkaline esophagitis: a comparison of the ability of components of gastroduodenal contents to injure the rabbit esophagus.
Esophagitis, Peptic
Contribution of trypsin and cholate to the pathogenesis of experimental alkaline reflux esophagitis.
Esophagitis, Peptic
Morphological alterations in tryptic esophagitis: an experimental light microscopic and scanning and transmission electron microscopic study in rabbits.
Esophagitis, Peptic
Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity.
Esophagitis, Peptic
Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis.
Esophagitis, Peptic
Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats.
Esophagitis, Peptic
Taurodeoxycholate modulates the effects of pepsin and trypsin in experimental esophagitis.
Esophagitis, Peptic
[Action of trypsin inhibitors on the development of reflux esophagitis in rats.]
Esophagitis, Peptic
[Effect of FOY-305 on post-operative reflux esophagitis in rats (II). Analysis of mechanism in the pathogenesis of reflux esophagitis after total gastrectomy in rats]
Essential Hypertension
Effectiveness of Sepharose-bound trypsin versus liquid-phase trypsin plus benzamidine for activation of inactive renin in human plasma.
Essential Hypertension
[Comparative evaluation of the efficacy of methods of cryo- and trypsin activation of inactive renin in vitro]
Exocrine Pancreatic Insufficiency
Abnormalities of circulating immunoreactive pancreatic anionic trypsinogen in cystic fibrosis: an assay artifact due to cross-reacting serum antibodies.
Exocrine Pancreatic Insufficiency
Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Comparative study of serum trypsin levels and pancreatic exocrine function in chronic pancreatitis.
Exocrine Pancreatic Insufficiency
Determination of fecal fat and trypsin output in the evaluation of chronic canine diarrhea.
Exocrine Pancreatic Insufficiency
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Exocrine Pancreatic Insufficiency
Evaluation of tests of exocrine and endocrine pancreatic function in older patients with cystic fibrosis.
Exocrine Pancreatic Insufficiency
Exocrine pancreatic insufficiency after allogeneic bone marrow transplantation.
Exocrine Pancreatic Insufficiency
Hydrogen breath test with glucose in exocrine pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Hydrogen breath test with low-dose rice flour for assessment of exocrine pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Immunoactive trypsins in duodenal juice from children with gastrointestinal disorders.
Exocrine Pancreatic Insufficiency
Intestinal activities of trypsin, lipase, and phospholipase after a test meal. An evaluation of 474 examinations.
Exocrine Pancreatic Insufficiency
Plasma immunoreactive cationic trypsin(ogen) pattern in reserpinized rat model of cystic fibrosis. Resemblance to humans.
Exocrine Pancreatic Insufficiency
Postprandial cholecystokinin response in patients with chronic pancreatitis in treatment with oral substitutive pancreatic enzymes.
Exocrine Pancreatic Insufficiency
Proteases in the evaluation of pancreatic function and pancreatic disease.
Exocrine Pancreatic Insufficiency
Serum trypsin, alpha-amylase and lipase during bombesin stimulation in normal subjects and patients with pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
Exocrine Pancreatic Insufficiency
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
Exocrine Pancreatic Insufficiency
Total pancreatic insufficiency in pigs: a model to study intestinal enzymes and plasma levels of digestive hormones after pancreatic supplementation by a whole pancreas preparation.
Exocrine Pancreatic Insufficiency
Tubeless tests of exocrine pancreatic function in patients with cystic fibrosis.
Exocrine Pancreatic Insufficiency
Zinc and copper concentrations in serum, blood and liver in moderate experimental pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
[DETERMINATION OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS. A SPECIFIC SENSITIVE METHOD FOR THE DEMONSTRATION OF EXOCRINE PANCREATIC INSUFFICIENCY.]
Exocrine Pancreatic Insufficiency
[On the determination of trypsin and chymotrypsin activity in the feces of dogs and their significance in the diagnosis of chronic exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[On the treatment of pre- and postoperative pancreatic insufficiency with trypsin inhibitors in patients with gallbladder and stomach diseases.]
Exocrine Pancreatic Insufficiency
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
Fabry Disease
Endocytotic internalization of alpha-2-macroglobulin: alpha-galactosidase conjugate by cultured fibroblasts derived from Fabry hemizygote.
Factor XII Deficiency
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Fatty Liver
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
Fatty Liver
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Fatty Liver
Dual blockade of angiotensin-II and aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis.
Fatty Liver
Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice.
Fetal Growth Retardation
Activities of lipase and trypsin in duodenal juice of infants small for gestational age.
Fibrosarcoma
A sarcoma-derived protein regulates hepatocyte metabolism via autocrine production of tumor necrosis factor-alpha.
Fibrosarcoma
Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
Fibrosarcoma
Steps involved in activation of the pro-matrix metalloproteinase 9 (progelatinase B)-tissue inhibitor of metalloproteinases-1 complex by 4-aminophenylmercuric acetate and proteinases.
Food Hypersensitivity
Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice.
Foot-and-Mouth Disease
Antibody and host cell recognition of foot-and-mouth disease virus (serotype C) cleaved at the Arg-Gly-Asp (RGD) motif: a structural interpretation.
Foot-and-Mouth Disease
Antibody response against foot and mouth disease virus (FMDV). Part I: Responses measured in sera of vaccinated steers with complete virus, trypsin treated virus, 12 S virus subunits and heterologous virus.
Foot-and-Mouth Disease
Antibody response against foot and mouth disease virus (FMDV). Part II: Responses measured in fractionated sera of infected steers with complete virus, trypsin treated virus, 12 S virus subunits, VIA and heterologous virus.
Foot-and-Mouth Disease
Application of monoclonal antibodies to quality control of foot-and-mouth disease vaccines.
Foot-and-Mouth Disease
Effect of trypsin and chymotrypsin on the polypeptides of large and small plaque variants of foot-and-mouth disease virus: relationship to specific antigenicity and infectivity.
Foot-and-Mouth Disease
Effect of trypsin treatment on the antigenic characteristics of plaque variants of type-O 1 and type Asia-1 foot-and-mouth disease viruses.
Foot-and-Mouth Disease
Foot-and-mouth disease virus: immunogenicity and structure of fragments derived from capsid protein VP and of virus containing cleaved VP.
Foot-and-Mouth Disease
Immunoreactivity and trypsin sensitivity of recombinant virus-like particles of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Nature of the inactivating action of trypsin on foot-and-mouth disease virus.
Foot-and-Mouth Disease
Ribonuclease contamination of crystalline deoxyribonclease, trypsin, and of partially purified foot-and-mouth disease virus preparations.
Foot-and-Mouth Disease
Type-independent detection of foot-and-mouth disease virus by monoclonal antibodies that bind to amino-terminal residues of capsid protein VP2.
Foot-and-Mouth Disease
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Fowlpox
An interferon-gamma-binding protein of novel structure encoded by the fowlpox virus.
Fusariosis
[Response of corn plants to the effect of salicylic acid and Fusarium moniliforme]
Galactosemias
Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs.
Galactosemias
Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia.
Gallbladder Neoplasms
Secretion of pancreatic secretory trypsin inhibitor by cultured human carcinoma cells.
Gallstones
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
Gallstones
A possible mechanism for gallstone pancreatitis: repeated short-term pancreaticobiliary duct obstruction with exocrine stimulation in rats.
Ganglion Cysts
[Experimental study of primary culture methods for spiral ganglion cells of newborn rats]
Gastric Fistula
The role of gastric secretion in post-diverted pancreatic hypersecretion in conscious rats.
Gastritis
[Evaluation of the intensity of the duodenogastric reflux based on the alkaline phosphatase and trypsin activities in the stomach contents]
Gastroenteritis
Isolation of group A human rotaviruses from faecal specimens in monkey MA-104 cells.
Gastroenteritis
Isolation of transmissible gastroenteritis virus from feces of diarrheic pigs in roller culture of CPK cells in the presence of trypsin.
Gastroenteritis
The multiplication of transmissible gastroenteritis viruses in several cell lines originated from porcine kidney and effects of trypsin on the growth of the viruses.
Gastroenteritis
The participation of antibody in spontaneous and antibody-dependent cell-mediated cytotoxicity in the pig.
Gastroenteritis
Three human rotavirus serotypes demonstrated by plaque neutralization of isolated strains.
Gastroenteritis
[Isolation of a concentrated purified preparation of the transmissible gastroenteritis virus of swine and a study of its antigenic properties]
Gastroesophageal Reflux
Bile acids and trypsin are unimportant in alkaline esophageal reflux.
Gastroesophageal Reflux
Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro.
Gastroesophageal Reflux
Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity.
Gastroesophageal Reflux
Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model.
Gastroesophageal Reflux
Trypsin induces biphasic muscle contraction and relaxation via transient receptor potential vanilloid 1 and neurokinin receptors 1/2 in porcine esophageal body.
Gastrointestinal Diseases
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
Gastrointestinal Diseases
[Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data]
Gastrointestinal Diseases
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Gastrointestinal Neoplasms
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Gastrointestinal Neoplasms
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
Gastrointestinal Neoplasms
Tumor-associated trypsin inhibitor, TATI, in gastrointestinal cancer and related benign diseases.
Gastroschisis
Intra-amniotic administration of urinary trypsin inhibitor preserves intestinal contractility in meconium induced intestinal damage in chick embryos with gastroschisis.
Gastroschisis
Urinary trypsin inhibitor present in fetal urine prevents intraamniotic meconium-induced intestinal damage in gastroschisis.
Genetic Diseases, Inborn
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
Genetic Diseases, Inborn
Was Ugo Foscolo (1778-1827) affected by alpha-1 antitrypsin deficiency?
Genetic Diseases, Inborn
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
Giant Axonal Neuropathy
Characterization of the intermediate filament apparatus in skin fibroblasts from patients with giant axonal neuropathy: effect of trypsin.
Giant Cell Tumors
Response to hormones of cells cultured from human giant cell tumors of bone.
Giant Cell Tumors
[Purification and study of the characteristics of the multinucleated giant cells of the giant cell tumor]
Gingival Pocket
[Increase in the sensitivity of the microflora of pathological gingival pockets to streptomycin under the influence of dimexide and trypsin]
Gingivitis
Adhesion of Porphyromonas gingivalis fimbriae to human gingival cell line Ca9-22.
Gingivitis
[Application of lyophilized trypsin in treatment of dry alveolus and ulcerative gingivitis]
Glaucoma
[Studies on pathological changes in cases of the aged retinal vessels, hypertension, and absolute glaucoma with the trypsin digestion method]
Glioblastoma
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Glioblastoma
cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Glioblastoma
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Glioblastoma
Production of amyloid beta protein precursor as a proteinase inhibitor by human astrocytic tumors.
Glioblastoma
Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
Glioblastoma
Purification and identification of a novel and four known serine proteinase inhibitors secreted by human glioblastoma cells.
Glioma
A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo.
Glioma
A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation.
Glioma
Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas.
Glioma
Inhibition by trypsin of the high-affinity acidic amino acid transport system in C6 glioma cells.
Glioma
Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
Glioma
Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
Glioma
Lymphokine activated killer (LAK) cell-mediated lysis of murine glioma: trypsin-chymotrypsin-sensitive glioma protein is responsible for tumor-selective recognition by LAK cells.
Glioma
Optimized dissociation protocol for isolating human glioma stem cells from tumorspheres via fluorescence-activated cell sorting.
Glioma
Trypsin promotes C6 glioma cell proliferation in serum- and growth factor-free medium.
Glomerulonephritis
Analyses of IgA1 hinge glycopeptides in IgA nephropathy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Glomerulonephritis
Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.
Glomerulonephritis
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Glomerulonephritis
Rapid accumulation of plasma acid-stable trypsin inhibitor in experimental acute renal injury.
Glomerulonephritis
Studies of trypsin inhibitor in urine. IV. The trypsin inhibitor in urine and serum of rabbits experimentally infected with streptococcus resulting in glomerulonephritis.
Glomerulonephritis
Urinary UK, t-PA and urinary trypsin inhibitor in health and glomerular diseases.
Glomerulonephritis
[Affinity sorbents with tripeptide morpholine ligands for isolation of proteases]
Glomerulonephritis
[Development of an immunoenzyme method for the quantitative determination of an acid-stable trypsin inhibitor in urine: use for assessing the severity of glomerulonephritis]
Glomerulonephritis
[Experimental glomerulonephritis induced by a new method. VII. On the nephrotoxin absorption activity common to ultrasupernatants of trypsin digestion in various tissue homogenates.]
Glomerulonephritis
[EXPERIMENTAL GLOMERULONEPHRITIS INDUCED BY A NEW PROCEDURE. X. ON THE ANTIGENICITY (NEPHROTOXIC ACTIVITY) OF THE ULTRASUPERNATANT OF KIDNEY TISSUE HOMOGENATE TREATED WITH TRYPSIN.]
Glomerulonephritis, IGA
Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.
Glomerulonephritis, IGA
Increase of IgA-bearing lymphocytes in peripheral blood from patients with IgA nephropathy.
Glomerulonephritis, Membranoproliferative
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Gout
A case report of acute pancreatitis with glycogen storage disease type IA in an adult patient and review of the literature.
Granuloma
Collagenase, elastase, and nonspecific protease production by vigorous or immunomodulated liver granulomas and granuloma macrophages/eosinophils of S mansoni-infected mice.
Granulomatosis with Polyangiitis
Alpha 1-antitrypsin activity is markedly decreased in Wegener's granulomatosis.
Graves Disease
A microcytotoxicity assay for thyroid-specific cytotoxic antibody, antibody-dependent cell-mediated cytotoxicity and direct lymphocyte cytotoxicity using human thyroid cells.
Head and Neck Neoplasms
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Heart Arrest
Insufficient production of urinary trypsin inhibitor for neutrophil elastase release after cardiac arrest.
Heart Arrest
Neuroprotection of ulinastatin on transient cerebral ischemia via antioxidative mechanisms.
Heart Diseases
Assessment of antibody mediated cytolysis of adult cardiocytes isolated by centrifugation in a continuous gradient of Percoll in patients with acute myocarditis.
Heart Diseases
Comparison of the chemical composition and nutritional value of Amaranthus cruentus flour and its protein concentrate.
Heart Diseases
Furazolidone-induced cardiomyopathy in turkeys. Association with a relative alpha1-antitrypsin deficiency.
Heart Diseases
Hepatitis, cardiomyopathy and hemodynamics in furazolidone-induced round heart disease of turkeys.
Heart Failure
Analysis of circulating forms of proBNP and NT-proBNP in patients with severe heart failure.
Heart Failure
Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice.
Hematologic Diseases
[Studies on immunity tests with Rh-sensitized and papain and trypsin treated erythrocytes in blood diseases.]
Hematologic Neoplasms
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Hematoma, Subdural
Early changes of arginine vasopressin and angiotensin II in patients with acute cerebral injury.
Hematuria
Effects of Hematuria on the Proteomic Profile of Urinary Extracellular Vesicles: Technical Challenges.
Hemophilia A
Effect of standardization and normalization on imprecision of calibrated automated thrombography: an international multicentre study.
Hemophilia A
Global coagulation assays in hemophilia A: A comparison to conventional assays.
Hepatitis
High prevalence of alpha 1 antitrypsin phenotypes in viral hepatitis B infected patients in Iran.
Hepatitis
Mouse hepatitis virus immunofluorescence in formalin- or Bouin's-fixed tissues using trypsin digestion.
Hepatitis
Overexpression of tumor-associated trypsin inhibitor (SPINK1/TATI) in hepatitis C-associated hepatocellular carcinoma: potential implications for viral hepatocarcinogenesis.
Hepatitis
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Hepatitis
Wedelolactone from Vietnamese Eclipta prostrata (L) L. Protected Zymosan-induced shock in Mice.
Hepatitis
[Effect of a trypsin and kallikrein inactivator in MHV3 induced experimental hepatitis in mice]
Hepatitis
[Effect of trypsin on the course of viral hepatitis and blood levels of various biochemical indicators]
Hepatitis
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Hepatitis
[Increasing of the trypsin rate frequency in the blood serum in children with viral hepatitis].
Hepatitis
[RESEARCH ON THE ACTION OF A KALLIKREIN AND TRYPSIN INHIBITOR ON THE COURSE OF EXPERIMENTAL HEPATITIS OF THE MOUSE DUE TO MHV-3.]
Hepatitis A
Protease digestion of hepatitis A virus: disparate effects on capsid proteins, antigenicity, and infectivity.
Hepatitis A
The unique role of domain 2A of the hepatitis A virus precursor polypeptide P1-2A in viral morphogenesis.
Hepatitis B
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Hepatitis B
Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
Hepatitis B
Tryptic cleavage of antibody binding sites from hepatitis B surface antigen particles.
Hepatitis C
Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires.
Hepatitis C
Use of a novel washing method combining multiple density gradients and trypsin for removing human immunodeficiency virus-1 and hepatitis C virus from semen.
Hepatitis C, Chronic
Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study.
Hepatitis C, Chronic
Examination of changes in TGF-beta1 and KL-6 expression over time in patients with chronic hepatitis C by AT-II receptor blocker therapy.
Hepatitis, Chronic
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Hepatitis, Chronic
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Hepatitis, Chronic
[Activity of serum trypsin in patients with chronic hepatitis and liver cirrhosis as an index of extrasecretory function of the pancreas]
Hepatitis, Chronic
[Evaluation of the vegetable oil taken up into the duodenum as a factor in pancreozymin liberation in healthy persons and in digestive organ diseases]
Hepatitis, Chronic
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
Hepatitis, Chronic
[The effect of heterologous duodenal content on the motor activity of the duodenum]
Hepatoblastoma
Release of pancreatic secretory trypsin inhibitor from human hepatoblastoma cells on stimulation with cytokines.
Hepatoblastoma
Response to IL-6 stimulation of human hepatoblastoma cells: production of pancreatic secretory trypsin inhibitor.
Herpes Labialis
Studies on human epidermal Langerhans' cells: II. Activation of human T lymphocytes to herpes simplex virus.
Herpes Simplex
Non-phospholipid vesicles as carriers for peptides and proteins: production, characterization and stability studies.
Herpes Simplex
Studies on the attachment of herpes simplex virus. Effect of trypsin treatment.
Herpes Simplex
Study of cell surface antigens induced by herpes simplex virus. Note II. Some properties of the antigens.
Herpes Simplex
The unique N terminus of the herpes simplex virus type 1 large subunit is not required for ribonucleotide reductase activity.
Herpes Zoster
A homologue of pancreatic trypsin is localized in the acrosome of mammalian sperm and is released during acrosome reaction.
Herpes Zoster
A survey of the effects of proteases and glycosidases on culture of rabbit morulae to blastocysts.
Herpes Zoster
Blocking of human sperm-zona interaction by monoclonal antibodies to a glycoprotein family (ZP4) of porcine zona pellucida.
Herpes Zoster
Boar spermadhesin PSP-II: location of posttranslational modifications, heterodimer formation with PSP-I glycoforms and effect of dimerization on the ligand-binding capabilities of the subunits.
Herpes Zoster
Characteristics of monoclonal antibodies against porcine zona pellucida-3 and their functional relevance.
Herpes Zoster
Characterization of antigenic determinants on porcine zona pellucida-3 beta(ZP3 beta) glycoprotein by monoclonal antibodies.
Herpes Zoster
Characterization of the mouse sperm plasma membrane zona-binding site sensitive to trypsin inhibitors.
Herpes Zoster
Chromosome analysis of Murrah buffalo (Bubalus bubalis ) spermatozoa using zona-free hamster oocytes.
Herpes Zoster
Collagenase as an agent for dissolving the zona pellucida of hamster and mouse oocytes.
Herpes Zoster
Cytogenetic analysis of sperm nucleous components of iranian normal and sub-fertile individuals using zona free hamster oocytes.
Herpes Zoster
Development and viability of bovine preimplantation embryos after the in vitro infection with bovine herpesvirus-1 (BHV-1): immunocytochemical and ultrastructural studies.
Herpes Zoster
Development in vitro of investment-free marsupial embryos during cleavage and early blastocyst formation.
Herpes Zoster
Effect of aging and cold temperature storage of hamster ova as assessed in the sperm penetration assay.
Herpes Zoster
Effect of azorellanone, a diterpene from Azorella yareta Hauman, on human sperm physiology.
Herpes Zoster
Effects of the oviduct and wheat germ agglutinin on enzymatic digestion of porcine zona pellucidae.
Herpes Zoster
Embryo transfer as a means of controlling the transmission of viral infections. II. The in vitro exposure of preimplantation bovine embryos to infectious bovine rhinotracheitis virus.
Herpes Zoster
Embryo transfer as a means of controlling the transmission of viral infections. XI. The in vitro exposure of bovine and porcine embryos to vesicular stomatitis virus.
Herpes Zoster
Evidence for a role of the major glycoprotein in the structural maintenance of the pig zona pellucida.
Herpes Zoster
Evidence for the involvement of a species-specific embryonic protease in zona escape of hamster blastocysts.
Herpes Zoster
Exposure of bovine embryos to trypsin during washing does not decrease embryonic survival.
Herpes Zoster
Factors affecting the trypsin induced release of aldosterone in rat adrenal zona glomerulosa tissue.
Herpes Zoster
Generation and characterization of monoclonal antibodies to porcine zona pellucida-3 alpha glycoprotein.
Herpes Zoster
Glycosylated boar spermadhesin AWN-1 isoforms. Biological origin, structural characterization by lectin mapping, localization of O-glycosylation sites, and effect of glycosylation on ligand binding.
Herpes Zoster
Human spermatozoa attach to trypsin-treated hamster zonae pellucidae but do not undergo acrosome reactions.
Herpes Zoster
Identification of a secondary sperm receptor in the mouse egg zona pellucida: role in maintenance of binding of acrosome-reacted sperm to eggs.
Herpes Zoster
Immunologic evidence for addition of oviductal components to the hamster zona pellucida.
Herpes Zoster
Inhibition of acrosin activity with a trypsin inhibitor blocks human sperm penetration of the zona pellucida.
Herpes Zoster
Inhibition of the acrosome reaction by trypsin inhibitors and prevention of penetration of spermatozoa through the human zona pellucida.
Herpes Zoster
Investigation of some antimicrobial procedures on the in vitro development of early murine embryos aimed toward developing methods for the disinfection of mammalian embryos prior to transfer.
Herpes Zoster
Involvement of trypsin-like activity in binding of mouse spermatozoa to zonae pellucidae.
Herpes Zoster
Localization of epitopes for monoclonal antibodies at the N-terminus of the porcine zona pellucida glycoprotein pZPC.
Herpes Zoster
Maturation of hamster oocytes under chemically defined conditions and sperm penetration through the zona pellucida.
Herpes Zoster
Normal penetration of rabbit spermatozoa through a trypsin- and acrosin-resistant zona pellucida.
Herpes Zoster
PH-20 but not acrosin is involved in sperm penetration of the macaque zona pellucida.
Herpes Zoster
Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa.
Herpes Zoster
Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation.
Herpes Zoster
Production of polyclonal antibody to the bovine adrenal atrial natriuretic factor-R1 receptor.
Herpes Zoster
Protease activity involvement in the passage of mammalian sperm through the zona pellucida.
Herpes Zoster
Relationship between two types of mouse sperm surface sites that mediate binding of sperm to the zona pellucida.
Herpes Zoster
Relative efficacy of conventional sperm parameters and sperm penetration bioassay to assess bull fertility in vitro.
Herpes Zoster
Serine proteases selectively control the output of 18-hydroxycorticosterone and aldosterone in stimulated zona glomerulosa tissue of the rat adrenal.
Herpes Zoster
Spontaneous zona reaction in the mouse as a limiting factor for the time in which an oocyte may be fertilized.
Herpes Zoster
Studies on zona hardening in rat oocytes that are matured in vitro in a serum-free medium.
Herpes Zoster
The effectiveness of trypsin treatment to remove Sendai virus adhering to the zona pellucida of mouse preimplantation embryos.
Herpes Zoster
The zona-free hamster oocyte penetration test: a simple procedure using a DNA fluorescent stain to detect the male pronucleus formation.
Herpes Zoster
Topographical characterization of the domain structure of the bovine adrenal atrial natriuretic factor R1 receptor.
Herpes Zoster
Trypsin stimulation of aldosterone and 18-hydroxycorticosterone production by rat adrenal zona glomerulosa tissue is mediated by activation of protein kinase C.
Herpes Zoster
Trypsin treatment of bovine embryos after in vitro exposure to infectious bovine rhinotracheitis virus or bovine herpesvirus-4.
Herpes Zoster
Trypsin treatment of bovine ova after in vitro exposure to vesicular stomatitis virus.
Herpes Zoster
Ultrastructure of opossum oocyte investing coats and their sensitivity to trypsin and hyaluronidase.
Herpes Zoster
[Effects of agents used for removal of zona pellucida on human sperm penetration into zona-free hamster egg]
Herpes Zoster
[Obtaining zona-free ova from the golden hamster (Mesocricetus auratus Waterhouse)]
HIV Infections
Thrombin activates envelope glycoproteins of HIV type 1 and enhances fusion.
Hyaline Membrane Disease
[Trypsic inhibitors in serum and hyaline membrane disease (author's transl)]
Hydatidiform Mole
Flow cytometric DNA analyses of 105 fresh hydatidiform moles, with correlations to prognosis.
Hyperaldosteronism
[Comparative evaluation of the efficacy of methods of cryo- and trypsin activation of inactive renin in vitro]
Hyperalgesia
Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2.
Hyperalgesia
Chronic compression or acute dissociation of dorsal root ganglion induces cAMP-dependent neuronal hyperexcitability through activation of PAR2.
Hyperalgesia
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Hyperalgesia
The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR2).
Hyperalgesia
The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
Hyperalgesia
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Hypercalcemia
Mutations in the calcium-sensing receptor: A new genetic risk factor for chronic pancreatitis?
Hyperglycemia
Effect of acute hyperglycemia on basal and bombesin-stimulated pancreaticobiliary secretion in humans.
Hyperglycemia
Effect of acute hyperglycemia on basal and cholecystokinin stimulated exocrine pancreatic secretion in humans.
Hyperglycemia
Hyperglycemia reduces pancreaticobiliary secretion in response to modified sham feeding in humans.
Hyperglycemia
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Hyperglycemia
The control of hyperglycemia by a novel trypsin resistant oral insulin preparation in alloxan induced type I diabetic mice.
Hyperglycemia
The effect of acute hyperglycemia on meal-stimulated gastric, biliary, and pancreatic secretion, and serum gastrin.
Hyperinsulinism
Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones.
Hyperlipidemias
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Hyperlipidemias
Urinary Trypsin Inhibitor Reduced Inflammation Response Induced by Hyperlipidemia.
Hyperlipoproteinemia Type III
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hyperlipoproteinemias
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hyperparathyroidism, Primary
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Hypersensitivity
Anaphylactic reactions to a cow's milk whey protein hydrolysate (Alfa-Ré, Nestlé) in infants with cow's milk allergy.
Hypersensitivity
Cloning and expression of trypsin-encoding cDNA from Blattella germanica and its possibility as an allergen.
Hypersensitivity
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Hypersensitivity
Identification and partial purification of serologically defined Boophilus microplus larval antigens by natural ectoparasite exposure.
Hypersensitivity
Partial proteolysis as a probe of the conformation of the gamma subunit in activated soluble and membrane-bound chloroplast coupling factor 1.
Hypersensitivity
Serum trypsin inhibitory capacity and pi phenotypes. II. Prevalence of alpha1-antitrypsin deficiency in an allergy population.
Hypersensitivity
Two Cardiac Arrests that Occurred after the Administration of Sugammadex: A Case of Kounis Syndrome.
Hypersensitivity
[Anaphylactoid reaction to trypsin following local administration of Dontisolon ointment]
Hypersensitivity
[Effect of trypsin on the development of a humoral immune response and of delayed hypersensitivity]
Hypersensitivity, Delayed
Immunogenicity of hapten-carrier conjugates associated with liposomes.
Hypersensitivity, Delayed
[Effect of trypsin on the development of a humoral immune response and of delayed hypersensitivity]
Hypersensitivity, Immediate
Hypersensitivity to pancreatic extracts in parents of patients with cystic fibrosis.
Hypersensitivity, Immediate
Immediate hypersensitivity to hog trypsin resulting from industrial exposure.
Hypertension
Angiotensin-II administration is useful for the detection of liver metastasis from pancreatic cancer during pharmacoangiographic computed tomography.
Hypertension
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Hypertension
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension.
Hypertension
The renin-angiotensin system, blood pressure, and heart structure in patients with hereditary vitamin D-resistance rickets (HVDRR).
Hypertension
[A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension]
Hypertension
[An AT-II blocker in patients with type II diabetes and arterial hypertension]
Hypertension
[Effect of an angiotensin-converting-enzyme inhibitor on the plasma concentration of cytokines and vasoactive molecules in patients with coronary heart disease and hypertension].
Hypertension
[Effect of trypsin and heparin electrophoresis on the state of the kallikrein-kinin system in hypertension]
Hypertension
[Studies on pathological changes in cases of the aged retinal vessels, hypertension, and absolute glaucoma with the trypsin digestion method]
Hypertension
[The clinical and pharmacokinetic evaluation of two-route chemotherapy with cisplatin and sodium thiosulfate in combination with angiotensin II]
Hypertension
[The hypertensive effect induced with angiotensin II and the physiological and pharmacokinetic aspects of two-route chemotherapy using CDDP and STS]
Hypertension
[The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]
Hypertension
[Tumor vascularity under hypertension induced by intravenous infusion of angiotensin II--angiographic and radionuclide angiographic observations]
Hypertension
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
Hypertension, Malignant
Malignant hypertension: a syndrome associated with low plasma kininogen and kinin potentiating factor.
Hypertension, Malignant
Plasma-levels of endothelin-1 and angiotensin-II and reactivity of arterial blood pressure to exogenous sympathomimetics and vasoactive peptides in rat model of malignant renal hypertension.
Hypertension, Portal
Role of angiotensin II in liver fibrosis-induced portal hypertension and therapeutic implications.
Hypertension, Pulmonary
Proteinase-activated receptor (PAR)-mediated vasorelaxation in pulmonary arteries from normotensive and hypoxic pulmonary hypertensive rats.
Hypertension, Pulmonary
The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD).
Hypertension, Pulmonary
[Effect of captopril on hypoxia-induced pulmonary hypertension in pigs]
Hyperthyroidism
The effect of hyperthyroidism on gastric emptying rates and pancreatic exocrine and biliary secretion in man.
Hyperthyroidism
[Effects of experimental hyperthyroidism on the phospholipase A2, lipase, cholesterolesterase and trypsin activity of the pancreatic juice and of the pancreas in rats]
Hyperthyroidism
[PURPURA PROVOKED BY HYPERTHYROIDISM AND INFLUENCE ON THIS BY TRYPSIN AND A PROTEOLYTIC INHIBITOR.]
Hypoglycemia
Culture of islets of Langerhans from an infant with intractable neonatal hypoglycemia: cytochemical and radioimmunological studies.
Hypoglycemia
Reflex splanchnic nerve stimulation increases levels of proenkephalin A mRNA and proenkephalin A-related peptides in the rat adrenal medulla.
Hypoparathyroidism
Familial idiopathic hypoparathyroidism, sensorineural deafness and renal dysplasia.
Hypoproteinemia
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Hypotension
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
Hypotension
Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II.
Hypotension
Evidence for the involvement of a plasma kallikrein-kinin system in the immediate hypotension produced by endotoxin in anaesthetized rats.
Hypotension
Further evidence of bradykinin involvement in septic shock: reduction of kinin production in vivo and improved survival in rats by use of polymer tailored SBTI with longer t1/2.
Hypotension
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Hypotension
Involvement of EDHF in the hypotension and increased gastric mucosal blood flow caused by PAR-2 activation in rats.
Hypotension
Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation.
Hypotension
Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo.
Hypotension
Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.
Hypotension
[Pharmacological studies of FUT-175, nafamstat mesilate. II. Effects on experimental acute pancreatitis]
Hypothyroidism
Hypothyroidism with elevated pancreatic amylase and lipase without clinical symptoms: A case report.
Hypothyroidism
Protease inhibitors in sera as possible indicators of familial hypothyroidism.
Idiopathic Pulmonary Fibrosis
Detection of antibodies in serum of patients with idiopathic pulmonary fibrosis against isolated rat alveolar type II cells.
Idiopathic Pulmonary Fibrosis
Safety of postoperative administration of human urinary trypsin inhibitor in lung cancer patients with idiopathic pulmonary fibrosis.
Ileitis
Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.
Immunoglobulin G4-Related Disease
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Immunoglobulin Light-chain Amyloidosis
Optimal conditions and the advantages of using laser microdissection and liquid chromatography tandem mass spectrometry for diagnosing renal amyloidosis.
Incontinentia Pigmenti
Histopathologic and trypsin digestion studies of the retina in incontinentia pigmenti.
Infections
112 bluetongue virus infection in cattle after transfer of bovine in vivo-derived embryos.
Infections
A 65-kDa trypsin-sensible membrane cell protein as a possible receptor for dengue virus in cultured neuroblastoma cells.
Infections
A bacterially produced virus enhancing factor from an entomopoxvirus enhances nucleopolyhedrovirus infection in armyworm larvae.
Infections
A modified plaque assay method for accurate analysis of infectivity of influenza viruses with uncleaved hemagglutinin.
Infections
A Novel Helper Phage Enabling Construction of Genome-Scale ORF-Enriched Phage Display Libraries.
Infections
A Novel Neuraminidase-Dependent Hemagglutinin Cleavage Mechanism Enables the Systemic Spread of an H7N6 Avian Influenza Virus.
Infections
A protein secreted in vivo by Echinococcus granulosus inhibits elastase activity and neutrophil chemotaxis.
Infections
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Infections
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion.
Infections
Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level.
Infections
Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics.
Infections
Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode.
Infections
BMP9-induced osteogenetic differentiation and bone formation of muscle-derived stem cells.
Infections
Bovine herpesvirus-1 associated with single, trypsin-treated embryos was not infective for uterine tubal cells.
Infections
Cell surface receptors for lactate dehydrogenase-elevating virus on subpopulation of macrophages.
Infections
Cellular changes in primary rabbit kidney cells resembling those caused by certain viruses.
Infections
Changes in the intestinal enzyme activity of lambs during chronic infection with Trichostrongylus vitrinus.
Infections
Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein.
Infections
Characterization of avian reovirus-induced cell fusion: the role of viral structural proteins.
Infections
Characterization of Clostridium perfringens TpeL toxin gene carriage, production, cytotoxic contributions, and trypsin sensitivity.
Infections
Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry.
Infections
Characterization of SNP1, a cell wall-degrading trypsin, produced during infection by Stagonospora nodorum.
Infections
Characterization of the reproduction of influenza A epidemic viruses in cell cultures.
Infections
Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus.
Infections
Cleavage and serum reactivity of the severe acute respiratory syndrome coronavirus spike protein.
Infections
Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus.
Infections
Comparative analysis of expressed genes from cacao meristems infected by Moniliophthora perniciosa.
Infections
Comparative susceptibilities of insect cell lines to infection by the occlusion-body derived phenotype of baculoviruses.
Infections
Conditioned Medium from Enterohemorrhagic Escherichia coli-Infected T84 Cells Inhibits Signal Transducer and Activator of Transcription 1 Activation by Gamma Interferon.
Infections
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface density.
Infections
Deletion of the SNP1 trypsin protease from Stagonospora nodorum reveals another major protease expressed during infection.
Infections
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Infections
Development and viability of bovine preimplantation embryos after the in vitro infection with bovine herpesvirus-1 (BHV-1): immunocytochemical and ultrastructural studies.
Infections
Development of a rapid and sensitive quantitative assay for rotavirus based on flow cytometry.
Infections
Differential gene expression from midguts of refractory and susceptible lines of the mosquito, Aedes aegypti, infected with Dengue-2 virus.
Infections
Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
Infections
Discordant varicella-zoster virus glycoprotein C expression and localization between cultured cells and human skin vesicles.
Infections
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Infections
Effects of cell differentiation on replication of A/WS/33, WSN, and A/PR/8/34 influenza viruses in mouse brain cell cultures: biological and immunological characterization of products.
Infections
Effects of Clostridium perfringens beta-toxin on the rabbit small intestine and colon.
Infections
Effects of herpes simplex virus strains on human fibroblast and lymphocyte chromosomes and the localization of chromosomal aberrations.
Infections
Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes.
Infections
Efficient formation of vesicular stomatitis virus pseudotypes bearing the native forms of hepatitis C virus envelope proteins detected after sonication.
Infections
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.
Infections
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Infections
Enhanced production of infectious rotavirus in BSC-1 cell cultures by various factors in the presence of absence of trypsin.
Infections
Enhancement of antigen incorporation and infectivity of cell cultures by human rotavirus.
Infections
Enhancement of fluorescent antibody staining of viral antigens in formalin-fixed tissues by trypsin digestion.
Infections
Enhancement of plaque formation and cell fusion of an enteropathogenic coronavirus by trypsin treatment.
Infections
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Infections
Expression of HLA class I heavy chains and beta 2-microglobulin does not affect human cytomegalovirus infectivity.
Infections
Formation of bacteriophage MS2 infectious units in a cell-free translation system.
Infections
Freezing or adding trypsin inhibitor to equine intestinal contents extends the lifespan of Clostridium perfringens beta toxin for diagnostic purposes.
Infections
Genomes and transcriptomes of partners in plant-fungal-interactions between canola (Brassica napus) and two Leptosphaeria species.
Infections
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Infections
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.
Infections
Identification and characterization of taglin, a mannose 6-phosphate binding, trypsin-activated lectin from Giardia lamblia.
Infections
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Infections
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins.
Infections
Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity.
Infections
In situ cleavage of the baculovirus occlusion derived virus receptor binding protein P74 in the peroral infectivity complex.
Infections
In vitro silencing of a serine protease inhibitor suppresses Trichinella spiralis invasion, development, and fecundity.
Infections
In Vivo Efficacy of Anuran Trypsin Inhibitory Peptides against Staphylococcal Skin Infection and the Impact of Peptide Cyclization.
Infections
Infection of cultured human intestinal cells by monkey RRV and human Wa rotavirus as a function of intestinal epithelial cell differentiation.
Infections
Influence of Leishmania infection on blood-meal digestion in the sandflies Phlebotomus papatasi and P. langeroni.
Infections
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Infections
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania.
Infections
Intact intestinal mRNAs and intestinal epithelial cell esterase, but not Cryptosporidium parvum, reach mesenteric lymph nodes of infected mice.
Infections
Interaction of bovine viral diarrhea virus with bovine cumulus-oocyte complex during IVM: Detection in permissive cells.
Infections
Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium.
Infections
Intra-amniotic administration of exogenous pulmonary surfactant for improving in lung maturity of fetal rabbits with intrauterine infection caused by premature rupture of membranes.
Infections
Isolation and characterization of phagosomes containing Chlamydia psittaci from L cells.
Infections
Isolation and purification of amastigotes of Trypanosoma cruzi from cultured vero cells.
Infections
Lectin/glycan interactions play a role in recognition in a coral/dinoflagellate symbiosis.
Infections
Lepeophtheirus salmonis secretory/excretory products and their effects on Atlantic salmon immune gene regulation.
Infections
Lipid composition and amino acid uptake during rotavirus infection and protection with trypsin inhibitor in malnourished infant mice.
Infections
Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Infections
Molecular immune response of the American lobster (Homarus americanus) to the White Spot Syndrome Virus.
Infections
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
Infections
Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge.
Infections
Multiplication and haemadsorbing activity of infectious salmon anaemia virus in the established Atlantic salmon cell line.
Infections
Neonatal infection does not affect the immunoreactive trypsinogen screening test for cystic fibrosis.
Infections
New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage.
Infections
Newcastle Disease Virus Induced Pathologies Severely Affect the Exocrine and Endocrine Functions of the Pancreas in Chickens.
Infections
Novel Potential Biomarkers for Opisthorchis viverrini Infection and Associated Cholangiocarcinoma.
Infections
Peanut Seed Cultivars with Contrasting Resistance to Aspergillus parasiticus Colonization Display Differential Temporal Response of Protease Inhibitors.
Infections
Physiological and immunological characterization of Caribbean spiny lobsters Panulirus argus naturally infected with Panulirus argus Virus 1 (PaV1).
Infections
Polypeptide composition of rotavirus empty capsids and their possible use as a subunit vaccine.
Infections
Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation.
Infections
Protection against rotavirus challenge in mice orally inoculated with trypsin inhibitor.
Infections
Protective efficacy of trypsin inhibitor on the the gut following rotavirus infection in malnourished infant mice.
Infections
Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract.
Infections
Rapid focus reduction neutralization test of influenza A and B viruses in microtiter system.
Infections
Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion.
Infections
Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype.
Infections
Resistance of Phlebotomus papatasi to infection with Leishmania donovani is modulated by components of the infective bloodmeal.
Infections
Role of host trypsin-type serine proteases and influenza virus-cytokine-trypsin cycle in influenza viral pathogenesis. Pathogenesis-based therapeutic options.
Infections
Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut.
Infections
Role of the pneumococcal autolysin (murein hydrolase) in the release of progeny bacteriophage and in the bacteriophage-induced lysis of the host cells.
Infections
Role of trypsin in the replication of Avian metapneumovirus subtype C (strain MN-2a) and its entry into the Vero cells.
Infections
Role of VP3 in human rotavirus internalization after target cell attachment via VP7.
Infections
Rosellinia necatrix infection induces differential gene expression between tolerant and susceptible avocado rootstocks.
Infections
Rotavirus-specific protein synthesis is not necessary for recognition of infected cells by virus-specific cytotoxic T lymphocytes.
Infections
Sarcocystis neurona infection in gamma interferon gene knockout (KO) mice: Comparative infectivity of sporocysts in two strains of KO mice, effect of trypsin digestion on merozoite viability, and infectivity of bradyzoites to KO mice and cell culture.
Infections
Selection of rotavirus VP4 cell receptor binding domains for MA104 cells using a phage display library.
Infections
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Infections
Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice.
Infections
Specific macrophage immunity to Sendai virus: macrophage aggregation in vitro with Sendai virus by cytophilic antibodies.
Infections
Statistical optimization of influenza H1N1 production from batch cultures of suspension Vero cells (sVero).
Infections
Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.
Infections
Study of the chemical nature of Frp/3 cell recognition units for hepatitis A virus.
Infections
Stunting syndrome in broilers: effect of age and exogenous amylase and protease on performance, development of the digestive tract, digestive enzyme activity, and apparent digestibility.
Infections
Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
Infections
Susceptibility of rodent cell lines to rat coronaviruses and differential enhancement by trypsin or DEAE-dextran.
Infections
Susceptibility of staphylococcal biofilms to enzymatic treatments depends on their chemical composition.
Infections
Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus.
Infections
Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection.
Infections
Temporal synthesis of proteins and RNAs during human astrovirus infection of cultured cells.
Infections
The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method.
Infections
The effect of proteolytic enzymes and protease inhibitors on the interaction Trypanosoma cruzi-fibroblasts.
Infections
The effect of surface membrane modifications of fibroblastic cells on the entry process of Trypanosoma cruzi trypomastigotes.
Infections
The effects of midgut serine proteases on dengue virus type 2 infectivity of Aedes aegypti.
Infections
The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases?
Infections
The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis.
Infections
The trypsin-enhanced infection of porcine epidemic diarrhea virus is determined by the S2 subunit of the spike glycoprotein.
Infections
The uristatin dipstick is useful in distinguishing upper respiratory from urinary tract infections.
Infections
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
Infections
Timecourse microarray analyses reveal global changes in gene expression of susceptible Glycine max (soybean) roots during infection by Heterodera glycines (soybean cyst nematode).
Infections
Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry.
Infections
Transformation of mouse peritoneal macrophages and bone marrow cells by simian virus 40.
Infections
Trypanosoma cruzi-fibroblastic cell interactions necessary for cellular invasion.
Infections
Trypanosoma cruzi: inhibition of host cell uptake of infective bloodstream forms by alpha-2-macroglobulin.
Infections
Trypsin and chymotrypsin-like enzymes of the sandfly Phlebotomus papatasi infected with Leishmania and their possible role in vector competence.
Infections
Trypsin cleavage of the baculovirus occlusion-derived virus attachment protein P74 is prerequisite in per os infection.
Infections
Trypsin of Litopenaeus vannamei is required for the generation of hemocyanin-derived peptides.
Infections
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Infections
Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model.
Infections
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Infections
Urinary trypsin levels observed in pancreas transplant patients with duodenocystostomies promote in vitro fibrinolysis and in vivo bacterial adherence to urothelial surfaces.
Infections
Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor.
Infections
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media.
Infections
Wolbachia infection in Aedes aegypti mosquitoes alters blood meal excretion and delays oviposition without affecting trypsin activity.
Infections
Xylanase supplementation of a wheat-based diet improved nutrient digestion and mRNA expression of intestinal nutrient transporters in broiler chickens infected with Clostridium perfringens.
Infections
[Analysis of SNPs and enzymatic disorder in the patients of influenza-associated encephalopathy: disorder of fatty acid metabolism in mitochondria induced by high fever]
Infections
[Clinical evaluation of the effect of a combination of tetracycline-L-methylenbysine with trypsin and alpha-chymotrypsin on acute and chronic oral infections]
Infections
[Comparative study of avian influenza virus propagation in the cell culture and chick embryos]
Infections
[Effect of proteolytic enzymes on kanamycin pharmacokinetics in experimental suppurative infection]
Infections
[Effects of intramuscular trypsin on the course of experimental infection by vaccinia virus in rabbits.]
Infections
[Study of incorporation of highly-cleaved H7 hemagglutinin, expressed by a recombinant vector in virions of superinfecting influenza viruses]
Infections
[The effect of oral rehydration therapy on pancreatic function in patients with acute intestinal infections]
Infections
[The influence of an infective dose and the duration of infection with Ascaridia galli on trypsin and alpha-amylase activity in the pancreas of chickens fed with diets of different protein levels]
Infections
[The treatment of urinary tract infection following transurethral prostatic resection by use of trypure solution.]
Infections
[Trypsin and alpha-amylase activities in the pancreas of guinea pigs. II. Effect of per os and intra-intestinal infection with invasive ova of Ascaris suum]
Infections
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. I. The influence of infective dose and duration of infection by Ascaris suum Goeze, 1782]
Infections
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. V. Effects of administration of vitamin A and B 2 during the larval stage of ascariasis]
Infections
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Infectious Bovine Rhinotracheitis
Evaluation of the effects of different trypsin treatments on semen quality after BHV-1 inactivation, and a comparison of the results before and after freezing, assessed by a computer image analyzer.
Infectious Bovine Rhinotracheitis
Trypsin treatment of bovine embryos after in vitro exposure to infectious bovine rhinotracheitis virus or bovine herpesvirus-4.
Infectious Mononucleosis
Impaired cellular immunecompetence in infectious mononucleosis as assessed by a local graft-versus-host reaction in rats and restoration of the immunecompetence by trypsin.
Infertility, Male
Tumor-associated trypsin inhibitor as a possible marker in male infertility.
Inflammatory Bowel Diseases
Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.
Inflammatory Bowel Diseases
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Inflammatory Bowel Diseases
Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon.
Inflammatory Bowel Diseases
Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance.
Influenza in Birds
A novel chicken lung epithelial cell line: characterization and response to low pathogenicity avian influenza virus.
Influenza in Birds
A viable recombinant rhabdovirus lacking its glycoprotein gene and expressing influenza virus hemagglutinin and neuraminidase is a potent influenza vaccine.
Influenza in Birds
Biological and genetic characterization of a low-pathogenicity avian influenza H6N2 virus originating from a healthy Eurasian coot.
Influenza in Birds
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Influenza in Birds
Evaluation of human intestinal epithelial differentiated cells (Caco-2) for replication, plaque formation and isolation of avian influenza viruses.
Influenza in Birds
Glycosylation at hemagglutinin Asn-167 protects the H6N1 avian influenza virus from tryptic cleavage at Arg-201 and maintains the viral infectivity.
Influenza in Birds
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Influenza in Birds
Mutations at the cleavage site of the hemagglutinin after the pathogenicity of influenza virus A/chick/Penn/83 (H5N2).
Influenza in Birds
Plaque morphology of Italian H7N1 LPAI isolates in MDCK cells and in primary cells of different avian species.
Influenza in Birds
Protease activation mutants elicit protective immunity against highly pathogenic avian influenza viruses of subtype H7 in chickens and mice.
Influenza, Human
A simplified plaque assay for influenza viruses in Madin-Darby kidney (MDCK) cells.
Influenza, Human
A viable recombinant rhabdovirus lacking its glycoprotein gene and expressing influenza virus hemagglutinin and neuraminidase is a potent influenza vaccine.
Influenza, Human
Accumulation of mini-plasmin in the cerebral capillaries causes vascular invasion of the murine brain by a pneumotropic influenza A virus: implications for influenza-associated encephalopathy.
Influenza, Human
Action of rimantadine on the structure of influenza A virus haemagglutinin.
Influenza, Human
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion.
Influenza, Human
Alterations in antioxidant defences in lung and liver of mice infected with influenza A virus.
Influenza, Human
An efficient method for introducing defined lipids into the plasma membrane of mammalian cells.
Influenza, Human
Animal viruses are able to fuse with prokaryotic cells. Fusion between Sendai or influenza virions and Mycoplasma.
Influenza, Human
Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein.
Influenza, Human
Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA.
Influenza, Human
Characterization of Site-Specific glycosylation in Influenza A Virus Hemagglutinin produced by Spodoptera frugiperda insect cell line.
Influenza, Human
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
Influenza, Human
Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: requirements for membrane fusion.
Influenza, Human
Conformationally selective biophysical assay for influenza vaccine potency determination.
Influenza, Human
Construction and characterization of an infectious vaccinia virus recombinant that expresses the influenza hemagglutinin gene and induces resistance to influenza virus infection in hamsters.
Influenza, Human
Correction to: IL-1b is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Influenza, Human
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface density.
Influenza, Human
Detection of influenza A and B neutralizing antibodies in vaccinated ferrets and macaques using specific biotin-streptavidin conjugated antibodies.
Influenza, Human
Differences in trypsin susceptibility among influenza viruses and relationship of the susceptibility to the antigenic type or subtype of the virus.
Influenza, Human
Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication.
Influenza, Human
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Influenza, Human
Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes.
Influenza, Human
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.
Influenza, Human
Electron microscopy of influenza virus growth in a human lymphoblastic leukemia cell line, MOLT4 cells.
Influenza, Human
Endogenous protease-dependent replication of human influenza viruses in two MDCK cell lines.
Influenza, Human
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Influenza, Human
Establishment of a genetically engineered chicken DF-1 cell line for efficient amplification of influenza viruses in the absence of trypsin.
Influenza, Human
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Influenza, Human
Evaluation of human intestinal epithelial differentiated cells (Caco-2) for replication, plaque formation and isolation of avian influenza viruses.
Influenza, Human
Factors responsible for plaque formation of A/duck/Siberia/272/1998 (H13N6) influenza virus on MDCK cells.
Influenza, Human
Genetic Recombination for Antigenic Markers of Antigenically Different Strains of Influenza B Virus.
Influenza, Human
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition.
Influenza, Human
Growth characteristics of influenza virus type C in avian hosts. Brief report.
Influenza, Human
Heterogeneity of the MDCK Cell Line and Its Applicability for Influenza Virus Research.
Influenza, Human
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
Influenza, Human
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Influenza, Human
Immunobiological properties of influenza A (H7N9) hemagglutinin and neuraminidase proteins.
Influenza, Human
Immunofluorescent staining of influenza virus antigen in fixed and paraffin-embedded tissue of experimentally infected hamsters.
Influenza, Human
Impact of cultivation conditions on N-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture.
Influenza, Human
Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity.
Influenza, Human
In ovo and in vitro susceptibility of American alligators (Alligator mississippiensis) to avian influenza virus infection.
Influenza, Human
Inactivation of hemagglutinating capacity of type A influenza virus by trypsin treatment.
Influenza, Human
Infection enhancement of influenza A NWS virus in primary murine macrophages by anti-hemagglutinin monoclonal antibody.
Influenza, Human
Influenza Hemagglutinin and M2 ion channel priming by trypsin: Killing two birds with one stone.
Influenza, Human
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Influenza, Human
Inhibition of influenza virus A/WSN replication by a trypsin inhibitor, 6-amidino-2-naphthyl p-guanidinobenzoate.
Influenza, Human
Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype.
Influenza, Human
Interaction of influenza virus hemagglutinin with target membrane lipids is a key step in virus-induced hemolysis and fusion at pH 5.2.
Influenza, Human
Interferon in nasal secretions from infants with viral respiratory tract infections.
Influenza, Human
MDCK cell cultures supplemented with high concentrations of trypsin exhibit remarkable susceptibility to influenza C virus.
Influenza, Human
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Influenza, Human
Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus.
Influenza, Human
Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain.
Influenza, Human
Mutation in the hemagglutinin of A/N-WS/33 influenza virus recombinants influencing sensitivity to trypsin and antigenic reactivity.
Influenza, Human
Necrotic Response to Low Pathogenic H9N2 Influenza Virus in Chicken Hepatoma Cells.
Influenza, Human
Optimization of trypsins for influenza A/H1N1 virus replication in MDCK SI-6 cells, a novel MDCK cell line.
Influenza, Human
Partial change of the ts-phenotype of cold-adapted influenza virus strain grown in canine kidney cells in the presence of trypsin.
Influenza, Human
Pathogenic significance of alpha-N-acetylgalactosaminidase activity found in the hemagglutinin of influenza virus.
Influenza, Human
Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin.
Influenza, Human
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Influenza, Human
Proteolytic enzymes in embryonated chicken eggs sustain the replication of egg-grown low-pathogenicity avian influenza viruses in cells in the absence of exogenous proteases.
Influenza, Human
Purification and cDNA cloning of a novel protease inhibitor secreted into culture supernatant by MDCK cells.
Influenza, Human
Replication of influenza A viruses in a green monkey kidney continuous cell line (Vero).
Influenza, Human
Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids.
Influenza, Human
Sequence and crystallization of influenza virus B/Beijing/1/87 neuraminidase.
Influenza, Human
SEROLOGIC AND ANTIGENIC PROPERTIES OF TYPE A INFLUENZA VIRUS AFTER TRYPSIN TREATMENT.
Influenza, Human
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses.
Influenza, Human
Stability of infectious influenza A viruses to treatment at low pH and heating.
Influenza, Human
Structural variation occurring in the hemagglutinin of influenza virus A/turkey/Oregon/71 during adaptation to different cell types.
Influenza, Human
Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
Influenza, Human
Susceptibility of continuous lines of monkey kidney cells to influenza and parainfluenza viruses in the presence of trypsin.
Influenza, Human
T cell recognition of the posttranslationally cleaved intersubunit region of influenza virus hemagglutinin.
Influenza, Human
Temperature sensitivity on growth and/or replication of H1N1, H1N2 and H3N2 influenza A viruses isolated from pigs and birds in mammalian cells.
Influenza, Human
The action of trypsin on normal serum inhibitors of influenza virus agglutination.
Influenza, Human
The action of vibrio and influenza virus enzymes and of periodate and trypsin on human red cells.
Influenza, Human
The cleavage of spike protein ??0???1/HA2 by trypsin permits activation of the M2 channel without its proteolytic cleavage in the influenza A virus.
Influenza, Human
The multiplication of an influenza C virus in an established line of canine kidney (MDCK) cells.
Influenza, Human
The use of components of plant origin in the development of production technology for live cold-adapted cultural influenza vaccine.
Influenza, Human
Thermolysin activation mutants with changes in the fusogenic region of an influenza virus hemagglutinin.
Influenza, Human
TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.
Influenza, Human
Transmembrane phospholipid motions induced by F glycoprotein in hemagglutinating virus of Japan.
Influenza, Human
Trypsin increases pseudorabies virus production through activation of the ERK signalling pathway.
Influenza, Human
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Influenza, Human
Ts mutations in the genome of cold-adapted variants of human influenza virus A/Krasnodar/101/59 (H2N2) at different passage levels and their reproduction in lungs of hamsters.
Influenza, Human
Ultrastructure and some biological properties of influenza A virus. IV. Effect of proteolytic enzymes on viral particle.
Influenza, Human
[Analysis of SNPs and enzymatic disorder in the patients of influenza-associated encephalopathy: disorder of fatty acid metabolism in mitochondria induced by high fever]
Influenza, Human
[Characteristics of virion formation during mixed infection with influenza viruses A and B]
Influenza, Human
[Comparative tests for destruction of specific inhibitors of hemagglutination due to influenza virus by treatment of sera with filtrate from cultures of Vibrio cholerae, potassium periodate and trypsin.]
Influenza, Human
[Pathogenic effect of pandemic influenza virus H1N1 under replication in cultures of human cells].
Influenza, Human
[Study of incorporation of highly-cleaved H7 hemagglutinin, expressed by a recombinant vector in virions of superinfecting influenza viruses]
Influenza, Human
[The properties of the epidemic influenza viruses A and B strains circulating in Russia in the 2004-2005 epidemic season]
Influenza, Human
[The trypsin cleavage of hemagglutinin enhances the infectivity of the influenza virus in mice]
Influenza, Human
[Use of plant-origin components in roller cultivation of vaccine reassortant influenza virus strain H5N2].
Insulin Resistance
beta-Hydroxybutyrate increases the insulin sensitivity of adipocyte glucose transport at a postreceptor level.
Insulin Resistance
Contraction-induced increase in muscle insulin sensitivity: requirement for a serum factor.
Insulin Resistance
Insulin resistance by uncleaved insulin proreceptor. Emergence of binding site by trypsin.
Insulin Resistance
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Insulin Resistance
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: resistance to proteolytic activation of glycogen synthase by trypsin.
Insulin Resistance
Sesquiterpenes from Baizhu Stimulate Glucose Uptake by Activating AMPK and PI3K.
Insulinoma
Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylase.
Insulinoma
Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.
Insulinoma
The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.
Intellectual Disability
Brief clinical report: interstitial deletion of the long arm of chromosome 10: del(10)(q11.2q21).
Intellectual Disability
Expression and Characterization of Human Fragile X Mental Retardation Protein Isoforms and Interacting Proteins in Human Cells.
Intervertebral Disc Degeneration
Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential.
Intervertebral Disc Degeneration
Human and bovine spinal disc mechanics subsequent to trypsin injection.
Intervertebral Disc Degeneration
Rheological and Dynamic Integrity of Simulated Degenerated Disc and Consequences after Cross-linker Augmentation.
Intestinal Obstruction
Pancreatic injury in equine acute abdomen evaluated by plasma trypsin activity and histopathology of pancreatic tissue.
Intestinal Obstruction
Plasma trypsin level in horses suffering from acute intestinal obstruction.
Intestinal Obstruction
Trypsin activity in stool and duodenal aspirate of neonates for differential diagnosis of intestinal obstruction.
Invasive Pulmonary Aspergillosis
Successful treatment of invasive pulmonary aspergillosis by transbronchial injection of urinary trypsin inhibitor and amphotericin B.
Irritable Bowel Syndrome
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Ischemic Attack, Transient
Ulinastatin alleviates neurological deficiencies evoked by transient cerebral ischemia via improving autophagy, Nrf-2-ARE and apoptosis signals in hippocampus.
Ischemic Stroke
Time course of inflammatory cytokines in acute ischemic stroke patients and their relation to inter-alfa trypsin inhibitor heavy chain 4 and outcome.
Keratosis, Seborrheic
Topical protease therapy as a novel method of epidermal ablation: preliminary report.
Kidney Calculi
Effects of ethylenediaminetetraacetic acid-4 sodium solution on the surface of renal calculi and the uroepithelium.
Kidney Diseases
[Comparison of the trypsin inhibitor activity in urine of donors and patients with kidney diseases]
Kidney Failure, Chronic
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Kidney Failure, Chronic
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Kidney Failure, Chronic
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
Kidney Failure, Chronic
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
Kidney Failure, Chronic
Plasma pancreatic trypsinogens in chronic renal failure and after nephrectomy.
Kidney Failure, Chronic
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Kidney Failure, Chronic
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Kidney Failure, Chronic
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Kidney Failure, Chronic
Trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.
Kidney Failure, Chronic
[Clinical value of the determination of urinary antitrypsin activity]
Kidney Failure, Chronic
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
Kidney Failure, Chronic
[Serum and urinary pancreatic secretory trypsin inhibitor concentration in patients with chronic renal failure]
Kounis Syndrome
Two Cardiac Arrests that Occurred after the Administration of Sugammadex: A Case of Kounis Syndrome.
Kwashiorkor
Exocrine pancreatic function of children from the Ivory Coast compared to French children. Effect of kwashiorkor.
Laryngitis
[Treatment of subglottic laryngitis in children; importance of local treatment with trypsin.]
Leg Ulcer
Biochemical and biological profile of a new enzyme preparation from Antarctic krill (E. superba) suitable for debridement of ulcerative lesions.
Leg Ulcer
Cleansing properties of stabilized trypsin and streptokinase-streptodornase in necrotic leg ulcers.
Leg Ulcer
Degradation and liquefaction effect of streptokinase-Streptodornase and stabilized trypsin on necroses, crusts of fibrinoid, purulent exudate and clotted blood from leg ulcers.
Leishmaniasis
Leishmania donovani donovani antigens recognized by kala-azar patient sera and identification of cross-reacting antigens to Chagas' disease.
Leishmaniasis, Visceral
A ?-mercaptoethanol-modified enzyme-linked immunosorbent assay for diagnosis of canine visceral leishmaniasis.
Leishmaniasis, Visceral
Evaluation of cleaving agents other than trypsin in direct agglutination test for further improving diagnosis of visceral leishmaniasis.
Leprosy, Lepromatous
Oxidation of 3,4-dihydroxyphenylalanine by connective tissue constituents. Identification of Mycobacterium leprae not related to phenolase activity.
Lethargy
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate.
Leukemia
Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro.
Leukemia
Extracellular protease trypsin activates amiloride-insensitive sodium channels in human leukemia cells.
Leukemia
Growth inhibition and induction of apoptosis in NB4 promyelocytic leukemia cells by trypsin inhibitor from sweet potato storage roots.
Leukemia
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Leukemia
Human T-cell leukemia-associated cell surface glycoprotein GP37: studies with three monoclonal antibodies and a rabbit antiserum.
Leukemia
Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells.
Leukemia
Isolation of an immunogenic polypeptide after limited trypsin hydrolysis of murine leukemia virus group-specific antigen.
Leukemia
Isolation of glycopeptides containing individual glycosylation sites of Friend murine leukemia virus glycoprotein: studies of glycosylation by methylation analysis.
Leukemia
Preserving catalytic activity and enhancing biochemical stability of the therapeutic enzyme asparaginase by biocompatible multilayered polyelectrolyte microcapsules.
Leukemia
Proteolysis of soluble IgE-receptor complexes: localization of sites on IgE which interact with the Fc receptor.
Leukemia
Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism.
Leukemia
Surface aminopeptidase activity of rat natural killer cells. I. Biochemical and biological properties.
Leukemia
The disulfide bond arrangement of leukemia inhibitory factor: homology to oncostatin M and structural implications.
Leukemia
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Leukemia
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
Leukemia
Urinary trypsin-inhibitor protects neutrophil chemotaxis in the inflammatory response.
Leukemia
Use of trypsin for rapid and efficient purification of murine sarcoma and leukemia virus.
Leukemia
[Identification of ectomesenchymal stem cells of human fetal facial processes and spontaneous differentiation to smooth muscle cells]
Leukemia
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
Leukemia
[Proteolytic activity and content of trypsin inhibitor in the blood serum of patients with leukemia]
Leukemia L1210
Chalone-like inhibition of Ehrlich ascites cell proliferation in vitro by an ultrafiltrate obtained from the ascitic fluid.
Leukemia L1210
Isolation and characterization of a novel trypsin inhibitor from fresh lily bulbs.
Leukemia L1210
Serine proteinase inhibitor from lymphocytic leukemia cells. Properties and copurification with DNA.
Leukemia L1210
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
Leukemia, Erythroblastic, Acute
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Leukemia, Hairy Cell
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Leukemia, Large Granular Lymphocytic
Identification and partial characterization of a novel plasma membrane-associated lytic factor isolated from highly purified adherent lymphokine-activated killer cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Leukemia, Lymphocytic, Chronic, B-Cell
Sodium periodate stimulation of normal and chronic lymphocytic leukemia lymphocytes. II. The use of neuraminidase and trypsin to probe the nature of the response.
Leukemia, Lymphoid
Chalone-like inhibition of Ehrlich ascites cell proliferation in vitro by an ultrafiltrate obtained from the ascitic fluid.
Leukemia, Lymphoid
Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and P85 glycoprotein.
Leukemia, Lymphoid
Serine proteinase inhibitor from lymphocytic leukemia cells. Properties and copurification with DNA.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Identification of variant translocations in chronic myeloid leukemia by fluorescence in situ hybridization.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Induction of apoptosis by buckwheat trypsin inhibitor in chronic myeloid leukemia K562 cells.
Leukemia, Myeloid, Acute
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Leukemia, Myeloid, Acute
[Apoptosis of HL-60 cells induced by recombinant common Buckwheat trypsin inhibitor]
Leukemia, Promyelocytic, Acute
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
Leukocytosis
Use of fibrinolytic agents in the prevention of postoperative adhesion formation.
Leukopenia
Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor.
Leukopenia
Leukocytes are required for the trypsin-induced increase in lung vascular permeability.
Lewy Body Disease
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Liver Cirrhosis
Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.
Liver Cirrhosis
Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor.
Liver Cirrhosis
Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development.
Liver Cirrhosis
Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats.
Liver Cirrhosis
Anti-fibrogenic effects of captopril and candesartan cilexetil on the hepatic fibrosis development in rat. The effect of AT1-R blocker on the hepatic fibrosis.
Liver Cirrhosis
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
Liver Cirrhosis
Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study.
Liver Cirrhosis
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
Liver Cirrhosis
pH and concentration of pancreatic enzymes in aspirates from the human duodenum during digestion of a standard meal in patients with biliary or hepatic disorders.
Liver Cirrhosis
Preventive effect of urinary trypsin inhibitor on the development of liver fibrosis in mice.
Liver Cirrhosis
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Liver Cirrhosis
Serum trypsin inhibitory capacity and alpha 1-antitrypsin levels in liver cirrhosis and hepatoma.
Liver Cirrhosis
[Activity of serum trypsin in patients with chronic hepatitis and liver cirrhosis as an index of extrasecretory function of the pancreas]
Liver Cirrhosis
[Postoperative change of serum protease inhibitor and C-reactive protein level--with special reference to surgical resection of liver cirrhosis]
Liver Cirrhosis, Alcoholic
Pancreatic secretion after secretin and cholecystokinin stimulation in chronic alcoholics with and without cirrhosis.
Liver Cirrhosis, Biliary
Mitochondrial antibodies in primary biliary cirrhosis. VI. Association of the complement fixing antigen with a component of the mitochondrial F1-ATPase complex.
Liver Cirrhosis, Biliary
Pancreatic involvement in patients with Sjögren's syndrome and primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Serum immunoreactive trypsin and pancreatic lipase in primary biliary cirrhosis.
Liver Cirrhosis, Biliary
The pancreas in primary biliary cirrhosis and primary sclerosing cholangitis.
Liver Diseases
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Liver Diseases
Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma.
Liver Diseases
Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
Liver Diseases
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Liver Diseases
Transport of proteases across neonatal intestine and development of liver disease in infants with alpha-1 antitrypsin deficiency.
Liver Diseases
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
Liver Neoplasms
Anti-tumoral effects of a trypsin inhibitor derived from buckwheat in vitro and in vivo.
Liver Neoplasms
Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts.
Liver Neoplasms
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Liver Neoplasms
Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy.
Lung Diseases
A community study of the relation of alpha1-antitrypsin levels to obstructive lung diseases.
Lung Diseases
Association of trypsin-2 with activation of gelatinase B and collagenase-2 in human bronchoalveolar lavage fluid in vivo.
Lung Diseases
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Lung Diseases
High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants.
Lung Diseases
Inhibition of neutrophil elastase-induced interleukin-8 gene expression by urinary trypsin inhibitor in human bronchial epithelial cells.
Lung Diseases
The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD).
Lung Diseases
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Lung Diseases
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
Lung Diseases
[Protease activity and the level of antibodies to connective tissue elements in various lung diseases]
Lung Diseases
[Proteolytic activity and trypsin inhibitor content in the blood serum in nonspecific lung diseases]
Lung Diseases, Interstitial
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases.
Lung Diseases, Interstitial
Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease.
Lung Diseases, Obstructive
Obstructive lung disease and trypsin inhibitors in alpha-1-antitrypsin deficiency.
Lung Diseases, Obstructive
Serum trypsin inhibitory capacity and Pi phenotypes. I. Methods and control values.
Lung Diseases, Obstructive
[Capacity of the serum trypsin inhibitor in chronic obstructive lung diseases]
Lung Injury
2',4',6'-Tris(methoxymethoxy) chalcone (TMMC) attenuates the severity of cerulein-induced acute pancreatitis and associated lung injury.
Lung Injury
Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Lung Injury
Effects of pulmonary artery perfusion with urinary trypsin inhibitor as a lung protective strategy under hypothermic low-flow cardiopulmonary bypass in an infant piglet model.
Lung Injury
Effects of ulinastatin treatment on the cardiopulmonary bypass-induced hemodynamic instability and pulmonary dysfunction.
Lung Injury
Effects of urinary protease inhibitor on inflammatory response during on-pump coronary revascularisation. Effect of ulinastatin on inflammatory response.
Lung Injury
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction.
Lung Injury
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis.
Lung Injury
New properties of the soybean trypsin inhibitor: Inhibition of human neutrophil elastase and its effect on acute pulmonary injury.
Lung Injury
Pancreatitis severity in mice with impaired CFTR function but pancreatic sufficiency is mediated via ductal and inflammatory cells-Not acinar cells.
Lung Injury
Protective Effect of Urinary Trypsin Inhibitor on the Development of Radiation-Induced Lung Fibrosis in Mice.
Lung Injury
Protective Effects of Lithospermum erythrorhizon Against Cerulein-Induced Acute Pancreatitis.
Lung Injury
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Lung Injury
Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.
Lung Injury
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor.
Lung Injury
Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury.
Lung Injury
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
Lung Injury
[Biological effect of (60)Cogamma ray on alveolar type II cells and interstitial cells of alveoliar septum in radiation pulmonary injury.]
Lung Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Lung Neoplasms
Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells.
Lung Neoplasms
Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients.
Lung Neoplasms
Isolation of urinary trypsin inhibitor-like inhibitor from human lung cancer tissue.
Lung Neoplasms
Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.
Lung Neoplasms
Monoclonal antibody that distinguishes small-cell lung cancer from non-small-cell lung cancer.
Lung Neoplasms
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Lung Neoplasms
Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells.
Lung Neoplasms
Safety of postoperative administration of human urinary trypsin inhibitor in lung cancer patients with idiopathic pulmonary fibrosis.
Lung Neoplasms
Serum alpha1-antitrypsin in patients with lung cancer or abnormal sputum cytology.
Lung Neoplasms
Trypsinization severely perturbs radioiodide transport via membrane Na/I symporter proteolysis: implications for reporter gene imaging.
Lupus Nephritis
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Lymphatic Metastasis
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Lymphoma
A novel trypsin inhibitor from Peltophorum dubium seeds, with lectin-like properties, triggers rat lymphoma cell apoptosis.
Lymphoma
A Storage Protein-Like Trypsin Inhibitor from the Moth Bean (Phaseolus acutifolius) with Antiproliferative Activity Toward Lymphoma Cells.
Lymphoma
Application of flow cytometry to studies on the distribution, persistence, and regeneration rate of Epstein-Barr virus receptors.
Lymphoma
Effects of horse and fetal calf serum on the expression of tumor-associated antigen and tumorigenicity of L5178Y leukemia/lymphoma cells.
Lymphoma
Increase in Gross (G) antigen sites on the surface of AKR virus-induced rat lymphoma cells after treatment with trypsin.
Lymphoma
Inhibition of [3H]TdR and [3H]CdR incorporation in an established human lymphoma cell line by trypsin treatment.
Lymphoma
Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells.
Lymphoma
Neuraminidase "unmasking" and failure of trypsin to "unmask" -D-galactose-like sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell membranes.
Lymphoma
Peltophorum dubium and soybean Kunitz-type trypsin inhibitors induce human Jurkat cell apoptosis.
Lymphoma
Silver enhancement of polymerised diaminobenzidine: increased sensitivity for immunoperoxidase staining.
Lymphoma
The effects of monensin on blood-borne arrest and glycosylation of BL/VL3 lymphoma cells.
Lymphoma, B-Cell
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Lymphoma, B-Cell
Immunoglobulin light chain staining in paraffin-embedded tissue using a heat mediated epitope retrieval method.
Lymphoma, B-Cell
Stable oligosaccharide microheterogeneity at individual glycosylation sites of a murine major histocompatibility antigen derived from a B-cell lymphoma.
Lymphoma, Follicular
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Lymphoma, Non-Hodgkin
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Lymphopenia
Do lymphocytes play a pro-inflammatory role in any pharmacological type of rat paw edema?
Macular Edema
Retinal trypsin digest study of cystoid macular edema associated with peripheral choroidal melanoma.
Malabsorption Syndromes
Comparison of ochratoxin, aflatoxin, and T-2 toxin for their effects on selected parameters related to digestion and evidence for specific metabolism of carotenoids in chickens.
Malabsorption Syndromes
Elevated levels of serum pancreatic secretory trypsin inhibitor (PSTI) in patients with malabsorption syndrome.
Malaria
Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana.
Malaria
Antibodies from malaria-exposed pregnant women recognize trypsin resistant epitopes on the surface of Plasmodium falciparum-infected erythrocytes selected for adhesion to chondroitin sulphate A.
Malaria
Antibody-mediated inhibition of Aedes aegypti midgut trypsins blocks sporogonic development of Plasmodium gallinaceum.
Malaria
Different effects of modulation of mosquito (Diptera:Culicidae) trypsin activity on the infectivity of two human malaria (Hemosporidia:Plasmodidae) parasites.
Malaria
Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria.
Malaria
Members of a trypsin gene family in Anopheles gambiae are induced in the gut by blood meal.
Malaria
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin.
Malnutrition
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Malnutrition
Comparative changes between pancreas and pancreatic juice digestive enzyme contents during nutritional rehabilitation following severe protein malnutrition in the rat.
Malnutrition
Elevated serum immunoreactive pancreatic cationic trypsinogen in acute malnutrition: evidence of pancreatic damage.
Malnutrition
PEGylated polymeric nanocapsules for oral delivery of trypsin targeted to the small intestines.
Malnutrition
Serum trypsin as measure of pancreatic exocrine function in children with protein calorie malnutrition.
Malnutrition
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Marek Disease
In vitro cytotoxicity against Marek's disease lymphoblastoid cell lines after enzymatic removal of Marek's disease tumor-associated surface antigen.
Marek Disease
Marek's Disease Herpesviruses I. Production and Preliminary Characterization of Marek's Disease Herpesvirus A Antigen.
Massive Hepatic Necrosis
Plasma and urine levels of urinary trypsin inhibitor in patients with acute and fulminant hepatitis.
Massive Hepatic Necrosis
Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.
Mastitis
Characterization of hemolytic activity of Staphylococcus aureus strains isolated from bovine mastitic milk.
Mastitis
Effect of frequent milkings on milk NAGase, plasmin, trypsin inhibitory capacity and the quality of whey as the growth medium for mastitis pathogens.
Mastitis
Factors affecting the distribution of lipoprotein lipase activity between serum and casein micelles in bovine milk.
Mastitis
Immuno-Detection of C3a, a C3 Complement Activated Product in Mastitis Milk, a Potential Diagnostic Marker.
Mastitis
Status of mastitis as an emerging disease in improved and periurban dairy farms in India.
Mastocytoma
Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue.
Measles
Affinity for measles virus anti-haemolysin of a residual immunoglobulin M in sera of some patients with multiple sclerosis.
Measles
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Measles
Enhancement of fluorescent antibody staining of viral antigens in formalin-fixed tissues by trypsin digestion.
Measles
Immunological relationships between homologous structural polypeptides of measles and canine distemper virus.
Measles
Isolation and comparative study of the nucleocapsids of measles and canine distemper viruses from infected cells.
Measles
Polar appearance and nonligand induced spreading of measles virus hemagglutinin at the surface of chronically infected cells.
Meconium Ileus
Immaturity of the myenteric plexus is the aetiology of meconium ileus without mucoviscidosis: a histopathologic study.
Meconium Ileus
Neonatal screening for cystic fibrosis in Wales and the West Midlands: 1. Evaluation of immunoreactive trypsin test.
Medulloblastoma
[Isolation and characterization of brain tumor stem cells in human medulloblastoma.]
Melanoma
Application of an improved density gradient electrophoresis apparatus to the separation of proteins, cells and subcellular organelles.
Melanoma
Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds.
Melanoma
Cell surface proteolysis by serine proteinases enhances RGD-sensitive melanoma cell adhesion on fibrinogen and vitronectin.
Melanoma
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin.
Melanoma
Comparison of the surface glycoprotein components in the isolated cells of hamster melanotic and amelanotic melanomas.
Melanoma
Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).
Melanoma
Cytoadherence characteristics of Plasmodium falciparum isolates from Thailand: evidence for chondroitin sulfate a as a cytoadherence receptor.
Melanoma
Enzymatic susceptibility and spontaneous release of human melanoma tumor-associated antigens.
Melanoma
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Melanoma
Immunochemical characterization of a tumor-associated antigen defined by a monoclonal antibody.
Melanoma
Inability of murine melanoma melanosomal "tyrosinase" (L-dopa oxidase) to oxidize tyrosine to melanin in polyacrylamide gel systems.
Melanoma
Influence of cell detachment on the respiration rate of tumor and endothelial cells.
Melanoma
Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II.
Melanoma
MDCK cell cultures supplemented with high concentrations of trypsin exhibit remarkable susceptibility to influenza C virus.
Melanoma
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Melanoma
Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach.
Melanoma
Partial characterisation of human melanoma cell-derived factors that stimulate fibroblast glycosaminoglycan synthesis.
Melanoma
Particulate tyrosinase of human malignant melanoma. Solubilization, purification following trypsin treatment, and characterization.
Melanoma
Polyenzyme preparation Wobe-Mugos inhibits growth of solid tumors and development of experimental metastases in mice.
Melanoma
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
Melanoma
Retinal trypsin digest study of cystoid macular edema associated with peripheral choroidal melanoma.
Melanoma
Stimulation of human metastatic melanoma colony-forming cells by an acid-sensitive factor in human platelet sonicate.
Melanoma
Tissue-cultured head and neck tumors: their use in in vitro assays of immune response.
Melanoma
Transient expression of high molecular weight, heat sensitive, trypsin-resistant form of tyrosinase in B-16 melanoma cells.
Melanoma, Amelanotic
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin.
Melanoma, Amelanotic
Heterogeneity of the surface material in isolated cells of transplantable hamster melanomas.
Melanoma, Experimental
Actin in B16 melanoma cells of differing metastatic potential. Effects of trypsin and serum.
Melanoma, Experimental
Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells.
Melanoma, Experimental
Distinct and non-cross-reactive epitopes are recognized on B16 melanoma by LAK cells and anti-B16 monoclonal antibodies.
Melanoma, Experimental
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Memory Disorders
Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase.
Meningioma
High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas.
Meningioma
Presence of the proteinase-activated receptor-2 (PAR-2) in human brain tumor cells--trypsin- and SLIGRL-induced calcium response in primary cultured meningiomas.
Menorrhagia
Hemorrhage induced by intrauterine devices: control by local proteinase inhibition.
Mesothelioma
Human mesothelioma cells produce factors that stimulate the production of hyaluronan by mesothelial cells and fibroblasts.
Mesothelioma
Hyaluronan receptors are expressed on human malignant mesothelioma cells but not on normal mesothelial cells.
Mesothelioma, Malignant
Urinary trypsin inhibitor suppresses migration of malignant mesothelioma.
Metabolic Diseases
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Metabolic Syndrome
A Trypsin Inhibitor from Tamarind Reduces Food Intake and Improves Inflammatory Status in Rats with Metabolic Syndrome Regardless of Weight Loss.
Metabolic Syndrome
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Metabolic Syndrome
Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.
Metabolic Syndrome
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
Metrorrhagia
Hemorrhage induced by intrauterine devices: control by local proteinase inhibition.
Metrorrhagia
Nano-LC based proteomic approach identifies that E6AP interacts with ENO1 and targets it for degradation in breast cancer cells.
Metrorrhagia
[Sample pre-processing for mass spectrometric analysis of glycoprotein structure]
Microaneurysm
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
Microaneurysm
Clinicopathologic correlations in diabetic retinopathy. I. Histology and fluorescein angiography of microaneurysms.
Microaneurysm
Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients.
Microaneurysm
Histopathology of argon laser photocoagulation in juvenile diabetic retinopathy.
Microaneurysm
The development of retinopathy in sucrose-fed and streptozotocin-diabetic rats.
Milk Hypersensitivity
Lymphocyte Responses to Chymotrypsin- or Trypsin V-Digested beta-Lactoglobulin in Patients with Cow's Milk Allergy.
Milk Hypersensitivity
T-cell epitope-containing hypoallergenic ?-lactoglobulin for oral immunotherapy in milk allergy.
Mitochondrial Encephalomyopathies
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Mixed Connective Tissue Disease
Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease.
Mouth Diseases
Antibody response against foot and mouth disease virus (FMDV). Part I: Responses measured in sera of vaccinated steers with complete virus, trypsin treated virus, 12 S virus subunits and heterologous virus.
Mouth Diseases
Antibody response against foot and mouth disease virus (FMDV). Part II: Responses measured in fractionated sera of infected steers with complete virus, trypsin treated virus, 12 S virus subunits, VIA and heterologous virus.
Mouth Diseases
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Mucocutaneous Lymph Node Syndrome
Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease: a retrospective study.
Mucocutaneous Lymph Node Syndrome
[Clinical utility of ulinastatin, urinary protease inhibitor in acute Kawasaki disease]
Multiple Myeloma
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Multiple Myeloma
Comparative study of workflows optimized for in-gel, in-solution, and on-filter proteolysis in the analysis of plasma membrane proteins.
Multiple Myeloma
Enzyme-induced modification of the surface properties of lymphoid cells in malignant disease. I. Effect of trypsin on rosette formation by lymphocytes in myelomatosis.
Multiple Myeloma
Expression of a buckwheat trypsin inhibitor gene in Escherichia coli and its effect on multiple myeloma IM-9 cell proliferation.
Multiple Sclerosis
A randomized, double-blind, placebo-controlled study of oral hydrolytic enzymes in relapsing multiple sclerosis.
Multiple Sclerosis
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes.
Multiple Sclerosis
Development of robust targeted proteomics assays for cerebrospinal fluid biomarkers in multiple sclerosis.
Multiple Sclerosis
Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4.
Multiple Sclerosis
Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse.
Mumps
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Mumps
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Mumps
[Favorable effect of trypsin on the receptivity of formalinized erythrocytes of the rat and mouse to mumps virus.]
Mumps
[Various mechanisms of the pathogenesis and etiotropic therapy of neurologic forms of epidemic parotitis]
Muscle Spasticity
Different reactivity of the proximal and distal segments of the radial artery to vasoconstrictors in patients undergoing coronary artery bypass grafting.
Muscular Dystrophy, Duchenne
Increased rate of cell-substratum detachment of fibroblasts from patients with Duchenne muscular dystrophy.
Myasthenia Gravis
[Myasthenia gravis probably caused by benzidamine hydrochloride, bromelains and trypsin]
Mycoses
A maize trypsin inhibitor (ZmTIp) with limited activity against Aspergillus flavus.
Myocardial Ischemia
Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
Myocardial Ischemia
[Effect of trypsin-like enzyme inhibitor on certain metabolic processes in the acute period of experimental myocardial ischemia]
Myocardial Ischemia
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias]
Myocarditis
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Myocarditis
Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis.
Myoma
Non-phosphorylative transglucosylation and other biochemical indices in serum and uterine myoma in women.
Myxoma
MALDI-TOF mass spectroscopy detects the capsid structural instabilities created by deleting the myxoma virus cupro-zinc SOD1 homolog M131R.
Nasopharyngeal Carcinoma
Two legume defense proteins suppress the mobility of nasopharyngeal carcinoma cells.
Neonatal Sepsis
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Neoplasm Metastasis
A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
Neoplasm Metastasis
A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer.
Neoplasm Metastasis
Activation of type IV procollagenases by human tumor-associated trypsin-2.
Neoplasm Metastasis
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Neoplasm Metastasis
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Neoplasm Metastasis
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Neoplasm Metastasis
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Neoplasm Metastasis
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Neoplasm Metastasis
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Neoplasm Metastasis
Characterization of the cellular binding site for the urinary trypsin inhibitor.
Neoplasm Metastasis
Clinicopathologic study of 62 acinar cell carcinomas of the pancreas: insights into the morphology and immunophenotype and search for prognostic markers.
Neoplasm Metastasis
Cytogenetic evidence for premeiotic transformation of human testicular cancers.
Neoplasm Metastasis
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Neoplasm Metastasis
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues.
Neoplasm Metastasis
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Neoplasm Metastasis
Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
Neoplasm Metastasis
Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
Neoplasm Metastasis
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Neoplasm Metastasis
Experimental studies on factors influencing the widespread organ distribution of Walker 256 tumour metastases.
Neoplasm Metastasis
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
Neoplasm Metastasis
Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
Neoplasm Metastasis
Hepatic arterial haemodynamics changes following intra-arterial angiotensin II infusion: duplex/colour Doppler sonography.
Neoplasm Metastasis
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Neoplasm Metastasis
Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor.
Neoplasm Metastasis
Identification of serum amyloid A as a biomarker to distinguish prostate cancer patients with bone lesions.
Neoplasm Metastasis
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Neoplasm Metastasis
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
Neoplasm Metastasis
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Neoplasm Metastasis
Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.
Neoplasm Metastasis
Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro.
Neoplasm Metastasis
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Neoplasm Metastasis
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Neoplasm Metastasis
Monitoring the treatment outcome in endometrial cancer patients by CEA and TATI.
Neoplasm Metastasis
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
Neoplasm Metastasis
Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
Neoplasm Metastasis
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
Neoplasm Metastasis
Proteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.
Neoplasm Metastasis
Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
Neoplasm Metastasis
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Neoplasm Metastasis
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Neoplasm Metastasis
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Neoplasm Metastasis
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
Neoplasm Metastasis
TGF-?1/ALK5-mediated cell migration is dependent on the protein PAR2 but not on PAR2-stimulated Gq-calcium signaling.
Neoplasm Metastasis
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Neoplasm Metastasis
The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
Neoplasm Metastasis
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Neoplasm Metastasis
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Neoplasm Metastasis
Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Neoplasm Metastasis
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
Neoplasm Metastasis
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
Neoplasm, Residual
Pre-operative serum level of tumour-associated trypsin inhibitor and residual tumour size as prognostic indicators in Stage III epithelial ovarian cancer.
Neoplasms
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis.
Neoplasms
A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
Neoplasms
A case of pancreatic mixed acinar-neuroendocrine carcinoma successfully diagnosed with endoscopic ultrasound-guided fine needle aspiration.
Neoplasms
A comparison of the usefulness of serum measurements of CA 125, CA 50 and TATI in patients with malignant and benign gynecological pathology.
Neoplasms
A Dual-Labeled Knottin Peptide for PET and Near-Infrared Fluorescence Imaging of Integrin Expression in Living Subjects.
Neoplasms
A high-density tissue microarray from patients with clinically localized prostate cancer reveals ERG and TATI exclusivity in tumor cells.
Neoplasms
A human colon adenocarcinoma xenograft--radiation response, cellular composition, and tumor disaggregation.
Neoplasms
A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells.
Neoplasms
A Persistent Solid Pseudopapillary Tumor of the Pancreas: Case Report and Brief Literature Review.
Neoplasms
A quantitative N-glycoproteomics study of cell-surface N-glycoprotein markers of MCF-7/ADR cancer stem cells.
Neoplasms
A role for protease-activated receptor-2 in pancreatic cancer cell proliferation.
Neoplasms
A soybean Kunitz trypsin inhibitor reduces tumor necrosis factor-alpha production in ultraviolet-exposed primary human keratinocytes.
Neoplasms
A trypsin inhibitor from rambutan seeds with antitumor, anti-HIV-1 reverse transcriptase, and nitric oxide-inducing properties.
Neoplasms
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Neoplasms
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature.
Neoplasms
Aflatoxin G1 induced TNF-?-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells.
Neoplasms
An alpha 2-macroglobulinlike activity in the blood of chelicerate and mandibulate arthropods.
Neoplasms
An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants.
Neoplasms
An improved mouse orthotopic bladder cancer model exhibiting progression and treatment response characteristics of human recurrent bladder cancer.
Neoplasms
Angiotensin-II administration is useful for the detection of liver metastasis from pancreatic cancer during pharmacoangiographic computed tomography.
Neoplasms
Antikeratin antibodies in tumor diagnosis. Distinction between seminoma and embryonal carcinoma.
Neoplasms
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Neoplasms
Antipeptide Immunocapture with In-Sample Calibration Curve Strategy for Sensitive and Robust LC-MS/MS Bioanalysis of Clinical Protein Biomarkers in Formalin-Fixed Paraffin-Embedded Tumor Tissues.
Neoplasms
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Neoplasms
Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.
Neoplasms
Application of Frontal Affinity Chromatography to Study the Biomolecular Interactions with Trypsin.
Neoplasms
Assessment of the tumor-associated trypsin inhibitor (TATI) marker in patients with carcinoma of the uterine body 17 years after treatment.
Neoplasms
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Neoplasms
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Neoplasms
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Neoplasms
Autocrine stimulation by prolactin of hormone-responsive breast cancer growth in culture.
Neoplasms
Avian tumour virus interactions with chicken fibroblast membranes: partial characterization of initial attachment site activity.
Neoplasms
Basement membrane alterations after treatment with trypsin, hyaluronidase or collagenase.
Neoplasms
beta-Naphthylamidase activity of the cell surface of ehrlich ascites cells. Reversible control of enzyme activity by metal ions and thiols.
Neoplasms
Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds.
Neoplasms
BIOCHEMICAL PROPERTIES OF CARBOXYPEPTIDASE A OF THE UNTRANSFERRED TISSUE AND MALIGNANT NEOPLASM OF THE MAMMARY GLAND.
Neoplasms
Blocking of lymphokine activated killer (LAK) cell mediated cytotoxicity by cell-sized beads bearing tumor cell proteins.
Neoplasms
Bombesin-stimulated serum immunoreactive trypsin in the differential diagnosis between endocrine and exocrine tumors of the pancreas.
Neoplasms
Bone and kidney adenylate cyclase-stimulating activity produced by a hypercalcemic canine adenocarcinoma line (CAC-8) maintained in nude mice.
Neoplasms
Buckwheat trypsin inhibitor enters Hep G2 cells by clathrin-dependent endocytosis.
Neoplasms
Cancer cell structure: actin changes in tumour cells--possible mechanisms for malignant tumour formation.
Neoplasms
Cancer-associated antigen CA 195 in patients with mucinous ovarian tumours: a comparative analysis with CEA, TATI and CA 125 in serum specimens and cyst fluids.
Neoplasms
Cationic trypsinogen produced by human pancreatic ductal cancer has the characteristics of spontaneous activation and gelatinolytic activity in the presence of proton.
Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Neoplasms
Cell coat in tumor cells -- effects of trypsin and EDTA: a biochemical and morphological study.
Neoplasms
Cell properties after repeated transplantation of spontaneously and of SV40 virus transformed mouse cell lines. I. Growth in culture.
Neoplasms
Cell survival and growth delay in rat R-1 tumours after radiation and vinblastine treatment.
Neoplasms
Changes in distribution of hepatic blood flow induced by intra-arterial infusion of angiotensin II in human hepatic cancer.
Neoplasms
Changes in growth and adhesion of Ehrlich ascites tumour cells coated with trypsin inhibitor (soybean).
Neoplasms
Changes in the collagenolytic activity released by primary VX-2 carcinoma cultures as a function of tumor growth.
Neoplasms
Characteristics of the chemotactic response of neoplastic cells to a factor derived from the fifth component of complement.
Neoplasms
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.
Neoplasms
Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature.
Neoplasms
Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.
Neoplasms
Cleavage of hexokinase II to two domains by trypsin without significant change in catalytic activity.
Neoplasms
Clinical usefulness of serum acute-phase reactants in patients with ovarian tumors.
Neoplasms
Co-Expression of a Chimeric Protease Inhibitor Secreted by a Tumor-Targeted Salmonella Protects Therapeutic Proteins from Proteolytic Degradation.
Neoplasms
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Neoplasms
Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1.
Neoplasms
Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
Neoplasms
Comparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines.
Neoplasms
Comparison of the surface glycoprotein components in the isolated cells of hamster melanotic and amelanotic melanomas.
Neoplasms
Conformational changes of rBTI from buckwheat upon binding to trypsin: implications for the role of the P(8)' residue in the potato inhibitor I family.
Neoplasms
Connective tissue degradation by invasive rat bladder carcinomas: action of nonspecific proteinases on collagenous matrices.
Neoplasms
Controlling nonspecific trypsin cleavages in LC-MS/MS-based shotgun proteomics using optimized experimental conditions.
Neoplasms
Could a plant derived protein potentiate the anticancer effects of a stem cell in brain cancer?
Neoplasms
Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
Neoplasms
Cytokeratin expression in cells of the rodent bile duct developing under normal and pathological conditions.
Neoplasms
Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells.
Neoplasms
Cytological findings and BCL10 expression in pancreatic acinar cell carcinoma: A Case Report.
Neoplasms
Cytomorphologic and immunophenotypical features of acinar cell neoplasms of the pancreas.
Neoplasms
Decreased plasma levels of cholecystokinin in healthy males after chronic ingestion of a heat-treated soya product.
Neoplasms
Demonstration and characterization of zeta (zeta), a growth-related opioid receptor, in a neuroblastoma cell line.
Neoplasms
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Neoplasms
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Neoplasms
Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections.
Neoplasms
Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy.
Neoplasms
Development of a murine intravesical orthotopic human bladder cancer (mio-hBC) model.
Neoplasms
Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy.
Neoplasms
Diagnostic and Prognostic Potential of Biomarkers CYFRA 21.1, ERCC1, p53, FGFR3 and TATI in Bladder Cancers.
Neoplasms
Diagnostic and prognostic value of tumor-associated trypsin inhibitor in gastrointestinal malignancies.
Neoplasms
Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment.
Neoplasms
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues.
Neoplasms
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
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Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
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Differential expression of tumor target binding and cytolytic activities in bone marrow culture-derived macrophages.
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Differential lysis of tumor target cells displayed by lymphokine activated killer (LAK) cell clones.
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Digestion of the fifth component of complement by leukocyte enzymes. Sequential generation of chemotactic activities for leukocytes and for tumor cells.
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Disaggregation of human solid tumours by combined mechanical and enzymatic methods.
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Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.
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Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.
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Dramatic increase in serum trypsinogens, SPINK1 and hCG? in aortic surgery patients after hypothermic circulatory arrest.
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Duplex/colour Doppler sonography: measurement of changes in hepatic arterial haemodynamics following intra-arterial angiotensin II infusion.
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Effect of an in vitro fertilization program on serum CA 125, tumor-associated trypsin inhibitor, free beta-subunit of human chorionic gonadotropin, and common alpha-subunit of glycoprotein hormones.
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Effect of crude trypsin on incorporation of 3H-thymidine and 3H-uridine into the Ehrlich ascites tumour cells.
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Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
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Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
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Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
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Effect of tumor dissaggregation on results of in vitro cell survival assay after in vivo treatment of the EMT-6 tumor: x-rays, cyclophosphamide, and bleomycin.
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Effect of ulinastatin on interleukins and pulmonary function in bypass patients: a meta-analysis of randomized controlled trials.
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Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes.
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Effects of estradiol on insulin receptor distribution in primary cultures of R3230AC mammary adenocarcinoma of the rat.
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Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
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Effects of RU486 and indomethacin on meiotic maturation, formation of extracellular matrix, and progesterone production by porcine oocyte-cumulus complexes.
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Effects of the synthetic trypsin inhibitor camostate on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
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Effects of trypsin on binding of insulin and concanavalin A and on glucose and proline transport in the R3230AC mammary adenocarcinoma.
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Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells.
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Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II for rat liver tumor.
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Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor.
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Efficient identification of proteins from ovaries and hepatopancreas of the unsequenced edible crab, Cancer pagurus, by mass spectrometry and homology-based, cross-species searching.
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Electron spin resonance and fluorescence observations on erythrocytes, erythrocyte membranes, 13762 MAT-A ascites adenocarcinoma cells, and their membranes, effects of membrane perturbations.
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Elevated serum insulin-like growth factor-binding protein 2 (IGFBP-2) and decreased IGFBP-3 in epithelial ovarian cancer: correlation with cancer antigen 125 and tumor-associated trypsin inhibitor.
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Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
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Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1.
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Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
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Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II.
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Enrichment of tumor cells for cell kinetic analysis in human tumor biopsies using cytokeratin gating.
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Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
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Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface.
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Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
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Establishment of two vaccine-associated feline sarcoma cell lines and determination of in vitro chemosensitivity to doxorubicin and mitoxantrone.
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Evidence for metal inhibition of tumour membrane-bound neutral protease and the control of tumour-induced target cell cytolysis.
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Evidence for the inhibition of trypsin by thiols. The mechanism of enzyme-inhibitor complex formation.
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Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
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Evidence of direct interaction between Kupffer cells and colon cancer cells: an ultrastructural study of the co-culture.
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Excretion of a tumor-associated trypsin inhibitor (TATI) in urine of patients with gynecological malignancy.
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Experimental studies on factors influencing the widespread organ distribution of Walker 256 tumour metastases.
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Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
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Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.
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Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.
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Fine needle aspiration cytology of acinar cell carcinoma of the pancreas: a report of two cases.
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Flow cytometric DNA analysis of 199 histologically favourable or unfavourable non-Hodgkin lymphomas.
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Functionalization of Carbon Nanomaterial Surface by Doxorubicin and Antibodies to Tumor Markers.
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Further characterization of the in vitro products generated by proteolytic cleavage of Gazdar murine sarcoma virus p65gag.
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Further inhibition studies on guanidinobenzoatase, a trypsin-like enzyme associated with tumour cells.
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Further studies on antitumour responses induced by short-term pretreatment with syngeneic tumour cells.
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Generation of a recombinant Sendai virus that is selectively activated and lyses human tumor cells expressing matrix metalloproteinases.
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Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies.
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Glucagon, glicentin, proglucagon, PYY, PP and proPP-icosapeptide immunoreactivities of rectal carcinoid tumors and related non-tumor cells.
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Glycoprotein metabolism in skin cancer: synthesis, pool size, and partial characterization of glycoproteins in the rat basosquamous cell carcinoma.
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Growth acceleration of Ehrlich ascites tumor cells treated by proteinase in vitro.
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Heat-regulated expression of the hepatitis B virus surface antigen in the human Wish cell line.
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Hemostasis following inoculation and during spreading of colon carcinoma in the rat.
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Hepatocellular carcinoma and intermediate alpha1-antitrypsin deficiency (MZ phenotype).
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Hereditary, familial, and idiopathic chronic pancreatitis are not associated with polymorphisms in the tumor necrosis factor alpha (TNF-alpha) promoter region or the TNF receptor 1 (TNFR1) gene.
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Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
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High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
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Highly sensitive IRS based biosensor for the determination of cytochrome c as a cancer marker by using nanoporous anodic alumina modified with trypsin.
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Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
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Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins.
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Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
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Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor.
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Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer.
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Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
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Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor.
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Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
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IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
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Immunohistochemical analysis of pancreatic secretory trypsin inhibitor expression in pulmonary adenocarcinoma: its possible participation in scar formation of the tumor tissues.
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Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma.
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Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts.
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Immunohistochemical characterization of an amphicrine mucinous islet-cell carcinoma of the pancreas. Case report.
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Immunohistochemical demonstration of pancreatic secretory trypsin inhibitor in gynecologic tumors.
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Immunohistochemical localization of pancreatic secretory trypsin inhibitor in malignant pancreatic endocrine tumors.
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In situ lymphoid cells of mouse mammary tumors. I. Development and evaluation of a method for the separation of lymphoid cells from mouse mammary tumors.
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Increased sensitivity of murine leukemia virus-infected tumor cells to lymphocyte-mediated cytotoxicity.
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Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
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Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
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Increasing stability and toxicity of Pseudomonas exotoxin by attaching an antiproteasic Peptide.
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Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
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Influence of Carbon Nanotubes and Its Derivatives on Tumor Cells In Vitro and Biochemical Parameters, Cellular Blood Composition In Vivo.
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Influence of trypsin on cytostatic effects of cyclophosphamide in rats with Guerin tumours.
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Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
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Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate.
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Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II.
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Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.
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Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.
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Inhibition of tumor cell invasion through matrigel by a peptide derived from the domain II region in urinary trypsin inhibition.
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Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
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Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor.
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Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro.
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Inhibitory effect of topical applications of nondenatured soymilk on the formation and growth of UVB-induced skin tumors.
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Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2.
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Inonotus obliquus polysaccharide regulates gut microbiota of chronic pancreatitis in mice.
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Inter-alpha-trypsin inhibitor bound to tumor cells is cleaved into the heavy chains and the light chain on the cell surface.
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Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
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Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells.
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Intra-arterial infusion chemotherapy with angiotensin-II for locally advanced and nonresectable pancreatic adenocarcinoma: further evaluation and prognostic implications.
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Intra-Tumor Heterogeneity Revealed by Mass Spectrometry Imaging Is Associated with the Prognosis of Breast Cancer.
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Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
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Intraductal Tubulopapillary Neoplasm of the Pancreas Masquerading as Pancreatic Neuroendocrine Carcinoma: Review of the Literature with a Case Report.
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Intrahepatic cholangiocarcinoma in a non-cirrhotic liver in a patient with homozygous ZZ alpha-1 antitrypsin deficiency.
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Intravenous injection of post-hemorrhagic shock mesenteric lymph induces multiple organ injury in rats.
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Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
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Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
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Isolation and characterization of a novel Bacillus thuringiensis strain expressing a novel crystal protein with cytocidal activity against human cancer cells.
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Kallikrein-related peptidases and associated microRNAs as promising prognostic biomarkers in gastrointestinal malignancies.
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Losartan reduces oxidative damage to renal DNA and conserves plasma antioxidant capacity in diabetic rats.
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Low alpha 2-macroglobulin-proteinase complex binding: a common but not exclusive characteristic of malignant cells.
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Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
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Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
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Macrophage and lymphocyte potentiation of syngeneic tumor cell and host fibroblast collagenolytic activity in rats.
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Maternal serum alpha-fetoprotein and epithelial tumour marker concentrations are not increased by fetal sacrococcygeal teratoma.
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Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat.
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Measurement of precursors for alpha-amidated hormones by radioimmunoassay of glycine-extended peptides after trypsin-carboxypeptidase B cleavage.
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Measurement of urinary trypsin inhibitor in urine, plasma and cancer tissues of patients with stomach cancer.
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Medullary thyroid carcinoma: ectopic production of peptides with ACTH-like, corticotrophin releasing factor-like and prolactin production-stimulating activities.
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Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation.
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Mesocestoides lineatus: trypsin induced development to adult mediated by Ca2+ and protein kinase C.
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Mg2+- or Mn2+-dependent p-nitrophenylphosphatase activity is present in Ehrlich ascites tumor cells.
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Microfluidic device for mechanical dissociation of cancer cell aggregates into single cells.
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Mining the cinnabaramide biosynthetic pathway to generate novel proteasome inhibitors.
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Mitogen-activated protein kinase inhibition enhances the antitumor effects of sporamin in human pancreatic cancer cells.
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Mitogen-induced disorganization of capillary-like structures formed by human large vessel endothelial cells in vitro.
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Mixed acinar-endocrine carcinoma of the pancreas with intraductal growth into the main pancreatic duct: Report of a case.
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Mixed acinar-endocrine carcinoma of the pancreas. A clinicopathological study and comparison with acinar-cell carcinoma.
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Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
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MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
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Murine macrophage cytotoxicity induced by mastocytoma cells, cell-free mastocytoma exudates, and extracts.
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Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
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Natural cytotoxicity in the mouse embryo: characterization of yolk sac-associated natural cytotoxic cells and their activity.
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Near infrared fluorescent trypsin stabilized gold nanoclusters as surface plasmon enhanced energy transfer biosensor and in vivo cancer imaging bioprobe.
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Near-Infrared Fluorescent and Magnetic Resonance Dual-Imaging Coacervate Nanoprobes for Trypsin Mapping and Targeted Payload Delivery of Malignant Tumors.
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Non-phosphorylative transglucosylation and other biochemical indices in serum and uterine myoma in women.
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Non-random chromosome changes in a herpes-virus-transformed Syrian hamster cell line and its metastatic derivatives.
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Observations on the histoformative capacities of tumor cells dissociated by digestion with trypsin.
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Observations on the inhibition of serum and cell surface enzymes by eicosapentaenoic acid.
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One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation.
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Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood.
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Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
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Overexpression of tumour-associated trypsin inhibitor (TATI) enhances tumour growth and is associated with portal vein invasion, early recurrence and a stage-independent prognostic factor of hepatocellular carcinoma.
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P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
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Pancreatic acinar cell carcinoma with a ductal adenocarcinoma component: a case report and analysis of the histogenesis of the tumor.
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Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
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Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.
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Pancreatic Ductal Adenocarcinoma Development in the Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma: A Case Report.
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Pancreatic mixed acinar-neuroendocrine carcinoma, a unique diagnostic challenge on FNA cytology: A small series of two cases with literature review.
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Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine.
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Pancreatic secretory trypsin inhibitor from human amniotic fluid and fetal and neonatal urine: concentrations and physicochemical characterization.
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Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
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Pancreatic secretory trypsin inhibitor-like immunoreactivity in pancreatectomized patients.
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Pancreatic-type acinar cell carcinoma of the liver: a clinicopathologic study of four patients.
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Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
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Persistent distension and enhanced diffusive extravasation of tumor vessels improved uniform tumor targeting of radioimmunoconjugate in mice administered with angiotensin II and kininase inhibitor.
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Pharmacologic intervention with angiotensin II and kininase inhibitor enhanced efficacy of radioimmunotherapy in human colon cancer xenografts.
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Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma.
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Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
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Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
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PO-44 - Tissue factor pathway inhibitor-2 (TFPI-2) is cleaved by PRSS3: implication for tumor endothelial cells migration.
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Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
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Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.
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Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
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Proceedings: Autoradiography of Ehrlich ascites tumours treated with soybean trypsin inhibitor in vivo.
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Proceedings: Independent responses of different binding sites on ehrlich ascites tumour cells to trypsin and trypsin inhibitor.
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Production of a serine-protease with macrophage migration-inhibitory factor activity by virus-transformed cells and human tumor cell lines.
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Production of bone-resorbing activity and colony-stimulating activity in vivo and in vitro by a human squamous cell carcinoma associated with hypercalcemia and leukocytosis.
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Production of macrophage activation factors by tryptic cleavage of calf serum proteins.
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Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin.
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Production of trypsins by human gastric cancer cells correlates with their malignant phenotype.
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Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
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Proliferative properties of the clonogenic cells of the R3327 prostate adenocarcinoma.
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Promoter hypomethylation of protease-activated receptor 2 associated with carcinogenesis in the stomach.
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Promotion of benign hyperplastic lesions in hamster cheek pouch by membrane labilizing agents and calcium ion: evidence that intracellular calcium-induced release from growth control is an obligatory preliminary stage of tumor promotion.
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Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts.
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Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.
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Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
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Protease-activated receptor-2 induces proinflammatory cytokine and chemokine gene expression in canine keratinocytes.
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Proteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.
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Proteinase-activated receptor-2-mediated signaling and inhibition of DNA synthesis in human pancreatic cancer cells.
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Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
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Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry.
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Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
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Proteomics of glycoproteins based on affinity selection of glycopeptides from tryptic digests.
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Rapid aggregation and tight junction formation in single cell suspensions of tumor cells after very low dose trypsin treatment.
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Rat mammary carcinoma cells secrete active collagenase and activate latent enzyme in the stroma via plasminogen activator.
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rBTI induces apoptosis in human solid tumor cell lines by loss in mitochondrial transmembrane potential and caspase activation.
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Reaction of a tumour-associated trypsin inhibitor with serine proteinases associated with coagulation and tumour invasion.
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Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy.
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Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis.
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Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
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Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes.
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Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources.
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Regulation of prostaglandin biosynthesis in dispersed choriodecidual cells in culture.
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Relationship between the changes in the concentration of endoxan and the activity of kininforming enzymes within the Guérin tumor in rat.
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Release of malignancy-related fucopeptides from ascites tumour cells in association with membrane vesicles.
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Renal function and serum concentration of five tumor markers (TATI, SCC, CYFRA 21-1, TPA, and TPS) in patients without evidence of neoplasia.
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Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases.
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Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin.
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Response of an in vivo-in vitro tumour to X-rays and cytotoxic drugs: effect of tumour disaggregation method on cell survival.
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Role of angiotensin II in liver fibrosis-induced portal hypertension and therapeutic implications.
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Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis.
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Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors.
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Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
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Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
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Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
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Serum alpha-1 proteinase inhibitor in advanced cancer: mass variants and functionally inert forms.
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Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
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Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
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Serum levels of tumor associated trypsin inhibitor (TATI) and glomerular filtration rate.
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Serum levels of tumor-associated trypsin inhibitor (TATI) in benign and malignant gynecological diseases.
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Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
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Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain.
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Sodium butyrate improved intestinal immune function associated with NF-?B and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella).
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SPINK1 is a prognosis predicting factor of non-small cell lung cancer and regulates redox homeostasis.
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Sporamin suppresses growth of xenografted colorectal carcinoma in athymic BALB/c mice by inhibiting liver ?-catenin and vascular endothelial growth factor expression.
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Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
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Steroid sequestration and tightly bound oestrogen-protein complexes in human breast tumours and a breast cancer cell line.
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Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
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Stimulation of reactive oxygen species production and cytotoxicity in human neutrophils in vitro and after oral administration of a polyenzyme preparation.
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Structure and function analysis of urinary trypsin inhibitor (UTI): identification of binding domains and signaling property of UTI by analysis of truncated proteins.
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SUBSTANCES AFFECTING ADULT TISSUE IN VITRO : I. THE STIMULATING ACTION OF TRYPSIN ON FRESH ADULT TISSUE.
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Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
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Suppression of lipopolysaccharide-induced cytokine production of gingival fibroblasts by a soybean, Kunitz trypsin inhibitor.
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Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells.
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Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
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Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.
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Synthesis and biological characterization of protease-activated prodrugs of doxazolidine.
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Systemic chemotherapy in tumor-bearing rats using high-dose cis-diamminedichloroplatinum(II) with low nephrotoxicity in combination with angiotensin II and sodium thiosulfate.
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TATI (tumor associated trypsin inhibitor) and cancer antigen 125 (CA 125) in patients with early-stage endometrial cancer.
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TGF-?1/ALK5-mediated cell migration is dependent on the protein PAR2 but not on PAR2-stimulated Gq-calcium signaling.
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The cytologic and immunohistochemical findings of pancreatic mixed acinar-endocrine carcinoma.
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The effect of anionic detergents and trypsin on mitochondria of normal and tumour tissues.
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The effect of intra-arterial angiotensin II on the hepatic tumor to non-tumor blood flow ratio for radioembolization: a systematic review.
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The effect of trypsin and neuraminidase on the circulation and organ distribution of tumor cells.
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The effects of ionizing irradiation on the sedimentation coefficient of cytoplasmic steroid receptors in rat mammary tumors.
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The feasibility of storing ovarian tumor cells on databasing paper: establishing a library of ovarian cancer DNA.
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The incidence of pulmonary tumors in mice exposed to aerosols of therapeutic agents; an evaluation of the possible carcinogenic properties of penicillin, pyribenzamine, adrenalin, cortisone, trypsin and desoxyribonuclease.
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The interaction of a trypsin-dependent neutral protease and its inhibitor found in tumour cells. Analysis of complex kinetic data involved in a thiol-disulphide exchange mechanism.
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The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
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The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
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The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
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The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
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The relationship between serum tumor-associated trypsin inhibitor levels and clinicopathological parameters in patients with gastric cancer.
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The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
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The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
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The widely-distributed tumour protein, oncomodulin, is a normal constituent of human and rodent placentas.
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Thermally self-assembled biodegradable poly(casein-g-N-isopropylacrylamide) unimers and their application in drug delivery for cancer therapy.
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Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Neoplasms
Tissue disaggregation of human renal cell carcinoma with further isopyknic and isokinetic gradient purification.
Neoplasms
Tissue-cultured head and neck tumors: their use in in vitro assays of immune response.
Neoplasms
TNF-?-dependent lung inflammation upregulates superoxide dismutase-2 to promote tumor cell proliferation in lung adenocarcinoma.
Neoplasms
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Neoplasms
Transient expression of high molecular weight, heat sensitive, trypsin-resistant form of tyrosinase in B-16 melanoma cells.
Neoplasms
Triple stimuli-responsive keratin nanoparticles as carriers for drug and potential nitric oxide release.
Neoplasms
Trophoblastic apoptosis in mice with preterm delivery and its suppression by urinary trypsin inhibitor.
Neoplasms
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Neoplasms
Trypsin induces tumour necrosis factor-alpha secretion from a human leukemic mast cell line.
Neoplasms
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.
Neoplasms
Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Neoplasms
Tumor associated trypsin inhibitor and CA-125 during treatment of mucinous ovarian cancer in 2 patients.
Neoplasms
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Neoplasms
Tumor markers CA 125, carcinoembryonic antigen and tumor-associated trypsin inhibitor in patients with cervical adenocarcinoma.
Neoplasms
Tumor-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA125) in patients with epithelial ovarian cancer.
Neoplasms
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
Neoplasms
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Neoplasms
Tumor-associated trypsin inhibitor in induced and acquired immunodeficiency. Studies on transplanted and HIV-infected patients.
Neoplasms
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Neoplasms
Tumor-host interactions in the rabbit V2 carcinoma: stimulation of cathepsin B in host fibroblasts by a tumor-derived cytokine.
Neoplasms
Tumor-targeted and nitric oxide-generated nanogels of keratin and hyaluronan for enhanced cancer therapy.
Neoplasms
Tumour-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA 125) in mucinous ovarian tumours.
Neoplasms
Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
Neoplasms
Tumour-associated trypsin inhibitor, carcinoembryonic antigen and acute-phase reactant proteins CRP and alpha1-antitrypsin in patients with gastrointestinal malignancies.
Neoplasms
Unique insight into microenvironmental changes in colorectal cancer: Ex vivo assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue.
Neoplasms
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Neoplasms
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Neoplasms
Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Neoplasms
Urinary trypsin inhibitor levels in the urine of patients with haematological malignancies.
Neoplasms
Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.
Neoplasms
Urinary trypsin inhibitor, a Kunitz-type protease inhibitor, modulates tumor necrosis factor-stimulated activation and translocation of protein kinase C in U937 cells.
Neoplasms
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Neoplasms
Urinary trypsin inhibitory capacity determination: study in patients with disseminated cancers.
Neoplasms
Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays.
Neoplasms
Vascular architecture as a diagnostic marker for differentiation of World Health Organization thymoma subtypes and thymic carcinoma.
Neoplasms
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
Neoplasms
[5-FU concentration in the tissue of gastric cancer, and evaluation of cancer chemotherapy with angiotensin-II]
Neoplasms
[A case of non-resectable pancreatic cancer surviving more than 4 years by intra-arterial infusion chemotherapy with angiotensin-II]
Neoplasms
[An effect of the intra-arterial infusion of angiotensin II in the chemotherapy of human hepatic cancer]
Neoplasms
[Association between natural cell mediated cytotoxicity (NCMC) and serum factors in acute leukemia and other malignant diseases]
Neoplasms
[CASES OF CANCER OF VATER'S AMPULLA TREATED WITH KALLIKREIN AND TRYPSIN INACTIVATOR (TRASYLOL).]
Neoplasms
[Changes in blood enzyme activity and tumor necrosis factor level in the treatment of experimental pancreatitis with pentoxifylline]
Neoplasms
[Clinical evaluation of tumor-associated trypsin inhibitor (TATI) in benign and malignant gynecological tumor]
Neoplasms
[Clinical significance of pancreatic secretory trypsin inhibitor assay as a tumor marker]
Neoplasms
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Neoplasms
[Experimental study of tumor directed therapy with gastric cancer monoclonal antibody-mitomycin conjugate combined with propranolol or angiotensin II]
Neoplasms
[Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis]
Neoplasms
[Possibility of improving cytological diagnosis by applying trypsin on lesions of the cervix uteri suspected of malignancy]
Neoplasms
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
Neoplasms
[Proteolytic enzymes and their inhibitors in the tumors and blood serum of patients with breast neoplasms]
Neoplasms
[Purification and study of the characteristics of the multinucleated giant cells of the giant cell tumor]
Neoplasms
[Radioimmunologic analysis of trypsin and C-peptide tumor markers for evaluation of treatment efficiency in patients with pancreatic and Vater's ampulla cancer]
Neoplasms
[Responses of cytokines, acute phase proteins, and polymorphonuclear cell elastase to surgical stress in the patients with esophageal cancer]
Neoplasms
[Significance of the the tumor markers, Ca-125 and tumor-associated trypsin inhibitor in patients with carcinoma of the cervix and uterus]
Neoplasms
[Specific proteinases in the urine of cancer patients. Comparative studies with modified Abderhalden reaction and a quantitative trypsin color test]
Neoplasms
[Study of plasminogen activator and trypsin inhibitor in gastric cancer, ulcer and experimental tumor.]
Neoplasms
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Neoplasms
[The diagnostic significance of pancreatic secretory trypsin inhibitor (PSTI) in patients with gynecologic tumors]
Neoplasms
[The effect of glycolytic enzymes on the metabolism of tumor cells. V. Proteolytic activation of fructose1,6-diphosphatase with trypsin.]
Neoplasms
[The hypertensive effect induced with angiotensin II and the physiological and pharmacokinetic aspects of two-route chemotherapy using CDDP and STS]
Neoplasms
[The relationship between opsonin, endotoxin and chemical mediators in postoperative complications after surgery]
Neoplasms
[The significance of determination of urinary trypsin inhibitor related antigen in patients with cancer of the digestive organs]
Neoplasms
[Tissue polypeptide antigen and tumor trypsin inhibitor in pleural effusions of various etiologies]
Neoplasms
[Trypsin resistance of natural and heat-treated cells; studies with leukocytes and ascites tumor cells of mice.]
Neoplasms
[Tumor vascularity under hypertension induced by intravenous infusion of angiotensin II--angiographic and radionuclide angiographic observations]
Neoplasms
[Tumor-associated trypsin inhibitor--an expanded tumor marker spectrum in cervix cancer?]
Neoplasms
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
Nephritis
Nephrotoxic serum nephritis in rats. II. Preparation and characterization of a soluble protective factor produced by trypsin digestion of rat tissue homogenates.
Nephritis
[Comparison of the trypsin inhibitor activity in urine of donors and patients with kidney diseases]
Nephritis, Hereditary
Trypsin digestion on paraffin sections is a useful tool for diagnosis of alport syndrome.
Nephrosis
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
Nephrotic Syndrome
Use of buccal trypsin in two diabetics with the nephrotic syndrome: a preliminary report.
Nephrotic Syndrome
[Concentration of acid-stable inhibitors--metabolites of plasma inter-alpha trypsin inhibitor--in the urine of healthy people and in patients with nephrotic syndrome]
Neuralgia
Urinary trypsin inhibitor attenuates the development of neuropathic pain following spinal nerve ligation.
Neuroblastoma
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Neuroblastoma
Characterization of cysteine proteases functioning in degradation of dynorphin in neuroblastoma cells: evidence for the presence of a novel enzyme with strict specificity toward paired basic residues.
Neuroblastoma
Evidence that neutral sphingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane.
Neuroblastoma
Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma.
Neuroblastoma
Membrane-bound trypsin-like enzyme functioning in degradation of dynorphin in neuroblastoma cells. Purification and characterization.
Neuroblastoma
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Neuroblastoma
[Surface charge of mouse neuroblastoma cells and changes during growth and morphologic differentiation of the cell population]
Neurogenic Inflammation
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
Neurogenic Inflammation
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
Neurogenic Inflammation
Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo.
Neurogenic Inflammation
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Neurogenic Inflammation
Protease-activated receptor 2 expression in trigeminal neurons innervating the rat nasal mucosa.
Neurogenic Inflammation
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
Neurogenic Inflammation
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Neuroinflammatory Diseases
Essential role of mitogen-activated protein kinase pathways in protease activated receptor 2-mediated nitric-oxide production from rat primary astrocytes.
Neuromyelitis Optica
Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse.
Neuronal Ceroid-Lipofuscinoses
Neuronal ceroid lipofuscinosis. A retinal trypsin digest study.
Neurosyphilis
[On the association of trypsin and penicillin in the therapy of neurosyphilis.]
Neutropenia
A case of Shwachman-Diamond syndrome confirmed with genetic analysis in a Korean child.
Nevus
Autologous skin reconstruction by combining epidermis and acellular dermal matrix tissue derived from the skin of giant congenital melanocytic nevi.
Newcastle Disease
A regular subunit pattern seen on non-infectious Newcastle disease virus particles.
Newcastle Disease
Plaque formation of Newcastle disease virus in primary chicken kidney cells.
Newcastle Disease
Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry.
Newcastle Disease
[Effect of proteolytic enzymes on the enhanced sensitivity of a cell culture of goat embryonic kidney to Newcastle disease virus]
Non-alcoholic Fatty Liver Disease
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Noonan Syndrome
De Novo Duplication of Chromosome 9p in a Female Infant: Phenotype and Genotype Correlation.
Obesity
Anti-TNF-? Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-? Induction.
Obesity
Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity.
Obesity
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Obesity
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Obesity
Serum proteomic biomarker discovery reflective of stage and obesity in breast cancer patients.
Obesity
Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L.
Obesity
Structure-Activity Relationship and Molecular Docking of a Kunitz-Like Trypsin Inhibitor, Kunitzin-AH, from the Skin Secretion of Amolops hainanensis.
Obesity
Tamarind Trypsin Inhibitor in Chitosan-Whey Protein Nanoparticles Reduces Fasting Blood Glucose Levels without Compromising Insulinemia: A Preclinical Study.
Obesity
Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic cholecystokinin levels.
Obesity
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
Obstetric Labor, Premature
Antenatal microbiologic and maternal risk factors associated with prematurity.
Obstetric Labor, Premature
Effect of urinary trypsin inhibitor on preterm labor with high granulocyte elastase concentration in cervical secretions.
Obstetric Labor, Premature
Effects of urinary trypsin inhibitor in patients at risk for premature labor with a bulging fetal membrane.
Obstetric Labor, Premature
Effects of urinary trypsin inhibitor on myometrial contraction in term and preterm deliveries.
Obstetric Labor, Premature
Re-evaluation of Urinary Trypsin Inhibitor on Pregnancy Course in Patients with Threatened Preterm Delivery: A Single-Center Retrospective Study.
Obstetric Labor, Premature
Urinary trypsin inhibitor: a new drug to treat preterm labor: a comparative study with ritodrine.
Osteoarthritis
Efficacy of Bromelain along with Trypsin, Rutoside Trihydrate Enzymes and Diclofenac Sodium Combination Therapy for the treatment of TMJ Osteoarthritis - A Randomised Clinical Trial.
Osteoarthritis
Human and bovine articular cartilage loading measured with a new resistive sensor: effects of protease degradation and osteoarthritis.
Osteoarthritis
Multicomponent analysis of T1 relaxation in bovine articular cartilage at low magnetic fields.
Osteoarthritis
Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee--a double-blind prospective randomized study.
Osteolysis
Staphylococcus epidermidis produces a cell-associated proteinaceous fraction which causes bone resorption by a prostanoid-independent mechanism: relevance to the treatment of infected orthopaedic implants.
Osteomyelitis
[Treatment of chronic osteomyelitis by intra-focal administration of antibiotics with trypsin.]
Osteoporosis
Isolation of therapeutically functional mouse bone marrow mesenchymal stem cells within 3 h by an effective single-step plastic-adherent method.
Osteosarcoma
Enhancement of production of IgM and interferon-beta in human cell lines by poly-lysine.
Osteosarcoma
Isolation and identification of cancer stem cells from human osteosarcom by serum-free three-dimensional culture combined with anticancer drugs.
Otitis
[Rational methods of use of trypsin in the treatment of chronic otitis (experimental studies)]
Otitis Externa
[The use of trypsin and lysozyme immobilized on a cellulose carrier in treating otitis externa]
Otosclerosis
Objective changes in trypsin, alpha 1-antitrypsin, and alpha 2-macroglobulin values as a result of sodium fluoride treatment in patients with otosclerosis.
Otosclerosis
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Out-of-Hospital Cardiac Arrest
Insufficient production of urinary trypsin inhibitor for neutrophil elastase release after cardiac arrest.
Ovarian Cysts
MUC-6 mucin is a major component of "blood group substance" from human ovarian cyst fluid.
Ovarian Cysts
Tumour-associated trypsin inhibitor (TATI) in human ovarian cyst fluid. Comparison with CA 125 and CEA.
Ovarian Diseases
Clinical usefulness of serum acute-phase reactants in patients with ovarian tumors.
Ovarian Hyperstimulation Syndrome
The Higher Response of Vascular Endothelial Growth Factor and Angiotensin-II to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome.
Ovarian Neoplasms
A novel proteomic biomarker panel as a diagnostic tool for patients with ovarian cancer.
Ovarian Neoplasms
A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Ovarian Neoplasms
Classification of cancer types by measuring variants of host response proteins using SELDI serum assays.
Ovarian Neoplasms
Effect of intracavitary radiotherapy on tumor-associated trypsin inhibitor (TATI) in patients with cervical and endometrial cancer.
Ovarian Neoplasms
Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells.
Ovarian Neoplasms
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
Ovarian Neoplasms
Expression of trypsinogen-1, trypsinogen-2, and tumor-associated trypsin inhibitor in ovarian cancer: prognostic study on tissue and serum.
Ovarian Neoplasms
Pancreatic secretory trypsin inhibitor from human amniotic fluid and fetal and neonatal urine: concentrations and physicochemical characterization.
Ovarian Neoplasms
Preoperative serum concentration of hCGbeta as a prognostic factor in ovarian cancer.
Ovarian Neoplasms
Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis.
Ovarian Neoplasms
Proteomic biomarkers for overall and progression-free survival in ovarian cancer patients.
Ovarian Neoplasms
Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer.
Ovarian Neoplasms
Role of serum-derived hyaluronan-associated protein-hyaluronan complex in ovarian cancer.
Ovarian Neoplasms
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Ovarian Neoplasms
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
Ovarian Neoplasms
The differentially mitochondrial proteomic dataset in human ovarian cancer relative to control tissues.
Ovarian Neoplasms
The feasibility of storing ovarian tumor cells on databasing paper: establishing a library of ovarian cancer DNA.
Ovarian Neoplasms
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Ovarian Neoplasms
Tumor associated trypsin inhibitor and CA-125 during treatment of mucinous ovarian cancer in 2 patients.
Ovarian Neoplasms
Tumour-associated trypsin inhibitor (TATI): comparison with CA125 as a preoperative prognostic indicator in advanced ovarian cancer.
Ovarian Neoplasms
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Ovarian Neoplasms
Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays.
Ovarian Neoplasms
[Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data]
Overweight
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
Overweight
[Effect of a reducing diet on metabolic disorders in ischemic heart disease patients having excess weight]
Pancreatic Diseases
13C-egg white breath test: a non-invasive test of pancreatic trypsin activity in the small intestine.
Pancreatic Diseases
Activities of gamma-glutamyl transferase, 5'-nucleotidase and alkaline phosphatase in human duodenal aspirate.
Pancreatic Diseases
An elevated ratio of serum anionic to cationic trypsinogen may signal pancreatic disease.
Pancreatic Diseases
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Pancreatic Diseases
Clinical evaluation of a serum trypsin determination method in pancreatic disease.
Pancreatic Diseases
Clinical significance of serum pancreatic enzymes in the quiescent phase of chronic pancreatitis.
Pancreatic Diseases
Coenzyme-Mediated Electro-RAFT Polymerization for Amplified Electrochemical Interrogation of Trypsin Activity.
Pancreatic Diseases
Concentration of immunoreactive trypsin and activity of pancreatic isoamylase in serum compared in pancreatic diseases.
Pancreatic Diseases
Diagnostic accuracy of serum cationic trypsinogen estimation for pancreatic diseases.
Pancreatic Diseases
Diagnostic value of fecal chymotrypsin and trypsin assessment for detection of pancreatic disease. A comparative study.
Pancreatic Diseases
Elastase-1 vs trypsin, lipase and amylase serum levels in pancreatic diseases.
Pancreatic Diseases
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Pancreatic Diseases
Elimination of trypsin inhibitor activity and beany flavor in soy milk by consecutive blanching and ultrahigh-temperature (UHT) processing.
Pancreatic Diseases
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Pancreatic Diseases
Immunohistochemical localization of pancreatic secretory trypsin inhibitor in fetal and adult pancreatic and extrapancreatic tissues.
Pancreatic Diseases
Increased interdigestive pancreatic trypsin secretion in alcoholic pancreatic disease.
Pancreatic Diseases
Intestinal activities of trypsin, lipase, and phospholipase after a test meal. An evaluation of 474 examinations.
Pancreatic Diseases
MEASUREMENT OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS TO DETECT CHRONIC PANCREATIC DISEASE.
Pancreatic Diseases
Normal duodenal trypsin values in response to secretin-pancreozymin stimulation with preliminary data in patients with pancreatic disease.
Pancreatic Diseases
Phenotypic changes in mouse pancreatic stellate cell Ca2+ signaling events following activation in culture and in a disease model of pancreatitis.
Pancreatic Diseases
Radioimmunoassay for human pancreatic secretory trypsin inhibitor: measurement of serum pancreatic secretory trypsin inhibitor in normal subjects and subjects with pancreatic diseases.
Pancreatic Diseases
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Pancreatic Diseases
Remote biosensor for the determination of trypsin by using nanoporous anodic alumina as a three-dimensional nanostructured material.
Pancreatic Diseases
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Pancreatic Diseases
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Pancreatic Diseases
Renal involvement in chronic pancreatic disease: effects on trypsin and amylase plasma-urine transfer.
Pancreatic Diseases
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Pancreatic Diseases
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Pancreatic Diseases
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
Pancreatic Diseases
Stimulation with cholecystokinin leads to increased ratio between mRNA levels for anionic and cationic trypsinogen in rat pancreas.
Pancreatic Diseases
The diagnostic value of faecal trypsin estimation in chronic pancreatic disease.
Pancreatic Diseases
The heat-induced protein aggregate correlated with trypsin inhibitor inactivation in soymilk processing.
Pancreatic Diseases
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
Pancreatic Diseases
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Pancreatic Diseases
The usefulness of trypsin determination in the serum in the diagnosis of pancreatic diseases in children.
Pancreatic Diseases
Thr28, Nle31 CCK-9--an useful CCK analogue in stimulation tests of pancreatic exocrine function.
Pancreatic Diseases
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Pancreatic Diseases
Trypsin and chymotrypsin determinations in human duodenal aspirate under the influence of continuous secretin-pancreozymin stimulation as an aid in the diagnosis of pancreatic disease.
Pancreatic Diseases
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Pancreatic Diseases
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Pancreatic Diseases
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
Pancreatic Diseases
[Changes in the serum pancreas enzyme following i.v. stimulation with secretin in subjects with a normal pancreas]
Pancreatic Diseases
[Determination of serum levels of trypsin in the diagnosis of pancreatic diseases]
Pancreatic Diseases
[Diagnosis of pancreatic disease (radioimmunological method for trypsin levels in blood]
Pancreatic Diseases
[Diagnostic significance of serum immunoreactive trypsin in pancreatic diseases (author's transl)]
Pancreatic Diseases
[Diagnostic value of chymotrypsin and trypsin activity determination in the feces in the diagnosis of pancreatic disease]
Pancreatic Diseases
[Diagnostic value of serum immunoreactive trypsin assay in pancreatic diseases using enzyme immunoassay]
Pancreatic Diseases
[Serum pancreatic secretory trypsin inhibitor (PSTI), amylase activity and pancreatic isoamylase activity in pancreatic diseases]
Pancreatic Diseases
[Serum trypsin inhibitor and trypsin binding protein in pancreatic diseases]
Pancreatic Diseases
[Studies on ribonuclease in the pancreatic juice of patient with pancreatic disease. II. Secretory pattern of ribonuclease, amylase and immunoreactive trypsin in duodenal juice during pancreozymin secretin test]
Pancreatic Diseases
[Value of pancreatic secretory trypsin inhibitor by radioimmunoassay in diagnosis of pancreatic diseases]
Pancreatic Diseases
[Value of the radioimmunologic measurement of serum trypsin in the study of pancreatic diseases. Preliminary studies]
Pancreatic Fistula
Pancreatic Inflammation and Proenzyme Activation Are Associated With Clinically Relevant Postoperative Pancreatic Fistulas After Pancreas Resection.
Pancreatic Fistula
The effect of SST, glucagon, calcitonin and PGE1 on exocrine pancreatic secretion in the unrestrained dog in long-term experiments.
Pancreatic Neoplasms
A role for protease-activated receptor-2 in pancreatic cancer cell proliferation.
Pancreatic Neoplasms
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Pancreatic Neoplasms
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Pancreatic Neoplasms
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells.
Pancreatic Neoplasms
Effect of synthetic protease inhibitor on histologic changes and free radical activity in hamsters with pancreatic cancer.
Pancreatic Neoplasms
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Pancreatic Neoplasms
Establishment of a human pancreatic cancer cell line and detection of pancreatic cancer associated antigen.
Pancreatic Neoplasms
Fractional urinary clearance of immunoreactive lipase in chronic pancreatic disease.
Pancreatic Neoplasms
Functional analysis of a pancreatic secretory trypsin inhibitor-like protein in insects: silencing effects resemble the human pancreatic autodigestion phenotype.
Pancreatic Neoplasms
Hereditary pancreatitis as the premalignant disease: a Japanese case of pancreatic cancer involving the SPINK1 gene mutation N34S.
Pancreatic Neoplasms
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Pancreatic Neoplasms
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Pancreatic Neoplasms
Marginal zinc status does not exacerbate pancreatic carcinogenesis associated with dietary soybean trypsin inhibitor concentrate in rats.
Pancreatic Neoplasms
Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach.
Pancreatic Neoplasms
Molecular size distribution of immunoreactive trypsin and renal tubular dysfunction: role in trypsin plasma-urine transfer.
Pancreatic Neoplasms
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Pancreatic Neoplasms
Novel mutations of PRSS1 gene in patients with pancreatic cancer among Han population.
Pancreatic Neoplasms
Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
Pancreatic Neoplasms
Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.
Pancreatic Neoplasms
Protease-activated receptor-2 expression and the role of trypsin in cell proliferation in human pancreatic cancers.
Pancreatic Neoplasms
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
Pancreatic Neoplasms
PRSS1 mutations and the proteinase/antiproteinase imbalance in the pathogenesis of pancreatic cancer.
Pancreatic Neoplasms
PRSS3 expression is associated with tumor progression and poor prognosis in epithelial ovarian cancer.
Pancreatic Neoplasms
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Pancreatic Neoplasms
Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy.
Pancreatic Neoplasms
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Pancreatic Neoplasms
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Pancreatic Neoplasms
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Pancreatic Neoplasms
Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis.
Pancreatic Neoplasms
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Pancreatic Neoplasms
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Pancreatic Neoplasms
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Pancreatic Neoplasms
Signal of proteinase-activated receptor-2 contributes to highly malignant potential of human pancreatic cancer by up-regulation of interleukin-8 release.
Pancreatic Neoplasms
The -409 C/T genotype of PRSS1 protects against pancreatic cancer in the Han Chinese population.
Pancreatic Neoplasms
The effect of corn trypsin inhibitor, anti-tissue factor pathway inhibitor antibodies and phospholipids on microvesicle-associated thrombin generation in patients with pancreatic cancer and healthy controls.
Pancreatic Neoplasms
The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
Pancreatic Neoplasms
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Pancreatic Neoplasms
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Pancreatic Neoplasms
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Pancreatic Neoplasms
Trypsin-protease activated receptor-2 signaling contributes to pancreatic cancer pain.
Pancreatic Neoplasms
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Pancreatic Neoplasms
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
Pancreatic Neoplasms
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Pancreatic Neoplasms
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases.
Pancreatic Neoplasms
Urinary enzymes excretion in pancreatic diseases. Clinical role and pathophysiological considerations.
Pancreatic Neoplasms
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Pancreatic Neoplasms
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Pancreatic Neoplasms
[Radioimmunologic analysis of trypsin and C-peptide tumor markers for evaluation of treatment efficiency in patients with pancreatic and Vater's ampulla cancer]
Pancreatic Pseudocyst
Pancreatic pseudocysts: a biochemical evaluation of proteases and protease inhibitors in plasma.
Pancreatic Pseudocyst
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
Pancreaticobiliary Maljunction
Activated pancreatic enzyme and pancreatic stone protein (PSP/reg) in bile of patients with pancreaticobiliary maljunction/ choledochal cysts.
Pancreaticobiliary Maljunction
Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation.
Pancreatitis
"Loss of function" mutations in the cationic trypsinogen gene (PRSS1) may act as a protective factor against pancreatitis.
Pancreatitis
A 93 year old man with the PRSS1 R122H mutation, low SPINK1 expression, and no pancreatitis: insights into phenotypic non-penetrance.
Pancreatitis
A carbon nanoparticle-peptide fluorescent sensor custom-made for simple and sensitive detection of trypsin.
Pancreatitis
A case of acute pancreatitis associated with cationic trypsinogen N29T mutation.
Pancreatitis
A CGC>CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis.
Pancreatitis
A method for determination of immunoreactive trypsin in complex with alpha 1-antitrypsin in human sera.
Pancreatitis
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
Pancreatitis
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
Pancreatitis
A novel A121T mutation in human cationic trypsinogen associated with hereditary pancreatitis: functional data indicating a loss-of-function mutation influencing the R122 trypsin cleavage site.
Pancreatitis
A novel thermosensitive in-situ gel of gabexate mesilate for treatment of traumatic pancreatitis: An experimental study.
Pancreatitis
A Paper-Based Near-Infrared Optical Biosensor for Quantitative Detection of Protease Activity Using Peptide-Encapsulated SWCNTs.
Pancreatitis
A possible mechanism for gallstone pancreatitis: repeated short-term pancreaticobiliary duct obstruction with exocrine stimulation in rats.
Pancreatitis
A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.
Pancreatitis
A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice.
Pancreatitis
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis.
Pancreatitis
A somatostatin analogue is protective against retrograde bile salt-induced pancreatitis in the rat.
Pancreatitis
A SPINK1 gene mutation in a Thai patient with fibrocalculous pancreatic diabetes.
Pancreatitis
A study on the activation peptide released from procarboxypeptidase B (CAPAP) and anionic trypsinogen in patients with acute abdominal disorders of non-pancreatic origin.
Pancreatitis
Acetaldehyde decreases the antitryptic activity of alpha 1-proteinase inhibitor.
Pancreatitis
Activated protein C in severe acute pancreatitis without sepsis? Not just yet ...
Pancreatitis
Activation of trypsinogen in experimental models of acute pancreatitis in rats.
Pancreatitis
Activation peptide of carboxypeptidase B and anionic trypsinogen as early predictors of the severity of acute pancreatitis.
Pancreatitis
Active pancreatic digestive enzymes show striking differences in their potential to damage isolated rat pancreatic acinar cells.
Pancreatitis
Acute Acinar Pancreatitis Blocks Vesicle-Associated Membrane Protein 8 (VAMP8)-Dependent Secretion Resulting in Intracellular Trypsin Accumulation.
Pancreatitis
Acute pancreatitis in Soweto, South Africa: relationship between trypsinogen load, trypsinogen activation, and fibrinolysis.
Pancreatitis
Acute pancreatitis: proteinase-activated receptor-2 as Dr. Jekyll and Mr. Hyde.
Pancreatitis
Alterations in intestinal function in acute pancreatitis in an experimental model.
Pancreatitis
An evaluation of the use of bile, bile salts, and trypsin in the production of experimental pancreatitis.
Pancreatitis
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Pancreatitis
Analysis of the hereditary pancreatitis-associated cationic trypsinogen gene mutations in exons 2 and 3 by enzymatic mutation detection from a single 2.2-kb polymerase chain reaction product.
Pancreatitis
Analysis of tumour necrosis factor alpha and interleukin 10 promotor variants in patients with chronic pancreatitis.
Pancreatitis
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Pancreatitis
Antiproteinase chemotherapy of acute experimental pancreatitis using the low molecular weight oligopeptide aldehyde leupeptin.
Pancreatitis
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Pancreatitis
Application of proteomic technology in identifying pancreatic secretory trypsin inhibitor variants in urine of patients with pancreatitis.
Pancreatitis
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Pancreatitis
Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.
Pancreatitis
Associations between gastrointestinal humoral factors and pancreatic proteolytic enzymes in alcohol-related versus non-alcohol-related pancreatitis.
Pancreatitis
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice.
Pancreatitis
Beneficial effect of therapeutic infusion of nafamostat mesilate (FUT-175) on hemodynamics in experimental acute pancreatitis.
Pancreatitis
Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats.
Pancreatitis
Beneficial effects of trypsin inhibitors derived from a spider venom peptide in L-arginine-induced severe acute pancreatitis in mice.
Pancreatitis
Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury.
Pancreatitis
BLOCKADE OF MULTIDRUG RESISTANCE ASSOCIATED PROTEINS AGGRAVATES ACUTE PANCREATITIS AND BLUNTS ATRIAL NATRIURETIC FACTOR BENEFITIAL EFFECT IN RATS: ROLE OF MRP4/ABCC4.
Pancreatitis
Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats.
Pancreatitis
Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis.
Pancreatitis
Cathepsin B Activates Human Trypsinogen 1 but Not Proelastase 2 or Procarboxypeptidase B.
Pancreatitis
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.
Pancreatitis
Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B.
Pancreatitis
CFTR and cationic trypsinogen mutations in idiopathic pancreatitis and neonatal hypertrypsinemia.
Pancreatitis
Changes in gene expression of pancreatitis-associated protein and pancreatic secretory trypsin inhibitors in experimental pancreatitis produced by pancreatic duct occlusion in rats: comparison with gene expression of cholecystokinin and secretin.
Pancreatitis
Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen.
Pancreatitis
Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription.
Pancreatitis
Characterization of novel genetic alterations in salivary gland secretory carcinoma.
Pancreatitis
Characterization of phospholipase A2 activity in aspirates of human pancreatic pseudocysts after isolation by reversed-phase high performance liquid chromatography.
Pancreatitis
Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis.
Pancreatitis
Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation.
Pancreatitis
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Pancreatitis
Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.
Pancreatitis
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y.
Pancreatitis
Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
Pancreatitis
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Pancreatitis
Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene.
Pancreatitis
Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Are Associated with Chronic Pancreatitis in Patients without Cystic Fibrosis.
Pancreatitis
Comparative studies on the analysis of urinary trypsin inhibitor (ulinastatin) preparations.
Pancreatitis
Comparison of elastase-1 with amylase, lipase, and trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.
Pancreatitis
Compartmentalization of the protease-antiprotease balance in early severe acute pancreatitis.
Pancreatitis
Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants.
Pancreatitis
Concentration of tissue angiotensin II increases with severity of experimental pancreatitis.
Pancreatitis
Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.
Pancreatitis
Continuous peritoneal dialysis in acute experimental pancreatitis in dogs. Effect of aprotinin in the dialysate medium.
Pancreatitis
Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent pancreatitis.
Pancreatitis
Correlation among complement activation, protease inhibitors, and clinical course in acute pancreatitis in man.
Pancreatitis
Correlation of pancreatic enzyme levels with the patient's recovery from acute edematous pancreatitis.
Pancreatitis
Correlation of trypsin-plasma inhibitor complexes with mortality in experimental pancreatitis in rats.
Pancreatitis
Current usage status of somatostatin and its analogs and trypsin inhibitors: a real-world study of 34,654 Chinese adult patients with acute pancreatitis.
Pancreatitis
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Pancreatitis
Cytokine suppressive agent improves survival rate in rats with acute pancreatitis of closed duodenal loop.
Pancreatitis
Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Pancreatitis
Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin.
Pancreatitis
Degradation and inactivation of plasma tumor necrosis factor-alpha by pancreatic proteases in experimental acute pancreatitis.
Pancreatitis
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis.
Pancreatitis
Differences in time course of hepatocyte and pancreocyte damage after incubation with trypsin, chymotrypsin and 2.4-dinitrophenol.
Pancreatitis
Different patterns in immunoreactive anionic and cationic trypsinogen in urine and serum in human acute pancreatitis.
Pancreatitis
Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models.
Pancreatitis
Do plasma and urine trypsinogen activation peptides (TAP) really increase in trypsin-taurocholate-induced pancreatitis?
Pancreatitis
Does antecedent ethanol intake affect course of taurocholate pancreatitis in rats?
Pancreatitis
Does heparin modify protease-antiprotease balance in acute experimental pancreatitis in rats.
Pancreatitis
Dramatic increase in serum trypsinogens, SPINK1 and hCG? in aortic surgery patients after hypothermic circulatory arrest.
Pancreatitis
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis.
Pancreatitis
Early complement system activation and neutrophil priming in acute pancreatitis: participation of trypsin.
Pancreatitis
Early sequential changes in serum markers of acute pancreatitis induced by endoscopic retrograde cholangiopancreatography.
Pancreatitis
Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.
Pancreatitis
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Pancreatitis
Effect of a new synthetic protease inhibitor on beta-endorphin release during acute pancreatitis in dogs.
Pancreatitis
Effect of a new synthetic trypsin inhibitor on taurocholate-induced acute pancreatitis in rats.
Pancreatitis
Effect of a new trypsin inhibitor in the therapy of experimental pancreatitis.
Pancreatitis
Effect of a synthetic protease inhibitor (Fut-175) on coagulation abnormalities during experimental acute pancreatitis in dogs.
Pancreatitis
Effect of acute pancreatitis on pulmonary transvascular fluid and protein exchange.
Pancreatitis
Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats.
Pancreatitis
Effect of chronic ethanol feeding on pancreatic enzyme secretion in rats in vitro.
Pancreatitis
Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models.
Pancreatitis
Effect of hemorrhagic and nortriptyline-induced shock on the porcine pancreas as evaluated by changes in serum cationic trypsin-like immunoreactivity.
Pancreatitis
Effect of intravenous and intraduodenal administration of Escherichia coli endotoxin on the porcine pancreas as evaluated by changes in the serum cationic trypsin-like immunoreactivity.
Pancreatitis
Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis.
Pancreatitis
Effect of parenteral and early intrajejunal nutrition on pancreatic digestive enzyme synthesis, storage and discharge in dog models of acute pancreatitis.
Pancreatitis
Effect of SMS201-995 (a long-acting somatostatin analog) on bile-induced acute hemorrhagic pancreatitis in the dog.
Pancreatitis
Effect of temporary ischemia upon development and histological patterns of acute pancreatitis in the rat.
Pancreatitis
Effect of urinary trypsin inhibitor on pancreatic cellular and lysosomal fragility in cerulein-induced acute pancreatitis in rats.
Pancreatitis
Effect on hemodynamics of therapeutic infusion of gabexate mesilate (FOY) in experimental acute pancreatitis.
Pancreatitis
Effectiveness of normal saline solution, dextran 40 or dextran 75, and aprotinin (Trasylol) on renal blood flow preservation during acute canine pancreatitis.
Pancreatitis
Effects of a bradykinin receptor antagonist (HOE140) on taurocholate-induced acute pancreatitis in rats.
Pancreatitis
Effects of a new cholecystokinin antagonist, TS-941, on experimental acute pancreatitis in rats.
Pancreatitis
Effects of a newly synthesized pancreatic protease inhibitor (PATM) on pancreatic microcirculation in experimental acute pancreatitis.
Pancreatitis
Effects of bradykinin receptor antagonist on the release of beta-endorphin and bradykinin and on hemodynamic changes in a canine model of experimental acute pancreatitis.
Pancreatitis
Effects of high-volume continuous hemofiltration on experimental pancreatitis associated lung injury in pigs.
Pancreatitis
Effects of protease inhibitor pretreatment on hemodynamic performances and survival rate in experimental, acute pancreatitis.
Pancreatitis
Effects of somatostatin on acute pancreatitis induced in rats by injection of taurocholate and trypsin into a temporarily closed duodenal loop.
Pancreatitis
Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis.
Pancreatitis
Effects on peritoneal proteolysis and hemodynamics of prophylactic infusion with C1 inhibitor in experimental acute pancreatitis.
Pancreatitis
Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
Pancreatitis
Electrochemically controlled grafting of polymers for ultrasensitive electrochemical assay of trypsin activity.
Pancreatitis
Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice.
Pancreatitis
Elevated levels of trypsinogen-2 and trypsin-2-alpha1-antitrypsin in sera of infants and children after cardiac surgery.
Pancreatitis
Elevated serum trypsin binding activity in patients with hereditary pancreatitis.
Pancreatitis
Emblica officinalis: a novel therapy for acute pancreatitis--an experimental study.
Pancreatitis
Endoscopic management of obstructive pancreatitis with a metal stent in two family members with hereditary cationic trypsinogen (PRSS1) deficiency.
Pancreatitis
Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B.
Pancreatitis
Enterokinase induced pancreatitis: its prevention with Trasylol and soybean trypsin inhibitor.
Pancreatitis
Ethanol augments elevated-[Ca2+]C induced trypsin activation in pancreatic acinar zymogen granules.
Pancreatitis
Evaluation of the cationic trypsinogen gene for potential mutations in miniature schnauzers with pancreatitis.
Pancreatitis
Evidence for extraluminal trypsinogen activation in three different models of acute pancreatitis.
Pancreatitis
Evidence of intracellular activation of serine proteases in acute cerulein-induced pancreatitis in rats.
Pancreatitis
Evolution of serum amylase, lipase and immunoreactive trypsin during pancreatitis attacks.
Pancreatitis
Exclusion of anionic trypsinogen and mesotrypsinogen involvement in hereditary pancreatitis without cationic trypsinogen gene mutations.
Pancreatitis
Exocrine function of caerulein-induced acute pancreatitis in anesthetized rats.
Pancreatitis
Exocrine pancreatic function (serum immunoreactive trypsin, fecal chymotrypsin, and pancreatic isoamylase) in Indian diabetics.
Pancreatitis
Exocrine pancreatic function, fecal fat, and blood glucose in patients with pancreatitis.
Pancreatitis
Experimental acute pancreatitis induced by excessive doses of caerulein in rats; protective and therapeutic effects of trypsin inhibitor urinastatin and CCK receptor antagonist CR1392.
Pancreatitis
Experimental acute pancreatitis--a quantification of dynamics at enzymic and histomorphologic levels.
Pancreatitis
Experimental pancreatitis in the dog. Appearance of complexes between proteases and trypsin inhibitors in ascitic fluid, lymph, and plasma.
Pancreatitis
Experimental pancreatitis in the dog. Demonstration of trypsin in ascitic fluid, lymph and plasma.
Pancreatitis
Experimental pancreatitis in the rat. Light and electron microscopical observations on early pancreatic lesions induced by intraductal injection of trypsin, phospholipase A2, lysolecithin and non-ionic detergent.
Pancreatitis
Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death.
Pancreatitis
Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells.
Pancreatitis
Expression of the adhesion molecules Mac-1 and L-selectin on neutrophils in acute pancreatitis is protease- and complement-dependent.
Pancreatitis
Failure of a potent trypsin inhibitor to modify experimental pancreatitis in dogs: p-aminobenzamidine.
Pancreatitis
Fox sign in a case of terminal stage pancreatic cancer and suggestions for diagnosis.
Pancreatitis
Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis.
Pancreatitis
FRET-based modified graphene quantum dots for direct trypsin quantification in urine.
Pancreatitis
From acute to chronic pancreatitis: the role of mutations in the pancreatic secretory trypsin inhibitor gene.
Pancreatitis
Functional analysis of a pancreatic secretory trypsin inhibitor-like protein in insects: silencing effects resemble the human pancreatic autodigestion phenotype.
Pancreatitis
Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution.
Pancreatitis
Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis.
Pancreatitis
Further evidence for endothelin as an important mediator of pancreatic and intestinal ischemia in severe acute pancreatitis.
Pancreatitis
Gabexate mesilate (FOY) protects against ceruletide-induced acute pancreatitis in the rat.
Pancreatitis
Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.
Pancreatitis
Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen.
Pancreatitis
Gene Conversion between Cationic Trypsinogen (PRSS1) and the Pseudogene Trypsinogen 6 (PRSS3P2) in Patients with Chronic Pancreatitis.
Pancreatitis
Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.
Pancreatitis
Genes, cloned cDNAs, and proteins of human trypsinogens and pancreatitis-associated cationic trypsinogen mutations.
Pancreatitis
Genetic Abnormalities in Pancreatitis: An Update on Diagnosis, Clinical Features, and Treatment.
Pancreatitis
Genetic analysis of the glutathione s-transferase genes MGST1, GSTM3, GSTT1, and GSTM1 in patients with hereditary pancreatitis.
Pancreatitis
Genetic aspects of chronic pancreatitis: insights into aetiopathogenesis and clinical implications.
Pancreatitis
Genetic background is different between sentinel and recurrent acute pancreatitis.
Pancreatitis
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis.
Pancreatitis
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction.
Pancreatitis
Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis.
Pancreatitis
Hereditary pancreatitis as the premalignant disease: a Japanese case of pancreatic cancer involving the SPINK1 gene mutation N34S.
Pancreatitis
Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.
Pancreatitis
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen.
Pancreatitis
Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism.
Pancreatitis
Hereditary pancreatitis in children: surgical implications with special regard to genetic background.
Pancreatitis
Hereditary pancreatitis in Japan: a review of pancreatitis-associated gene mutations.
Pancreatitis
Hereditary pancreatitis in North America: the Pittsburgh-Midwest Multi-Center Pancreatic Study Group Study.
Pancreatitis
Hereditary pancreatitis in Paediatrics: the causative role of p.Leu104Pro mutation of cationic trypsinogen gene also in young subjects.
Pancreatitis
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.
Pancreatitis
Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.
Pancreatitis
Hereditary pancreatitis: a model for understanding the genetic basis of acute and chronic pancreatitis.
Pancreatitis
Hereditary pancreatitis: clinical characteristics and diagnostic criteria in Japan.
Pancreatitis
Hereditary pancreatitis: clinical features and inheritance characteristics of the R122C mutation in the cationic trypsinogen gene (PRSS1) in six Spanish families.
Pancreatitis
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
Pancreatitis
Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.
Pancreatitis
Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells.
Pancreatitis
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Pancreatitis
Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.
Pancreatitis
Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.
Pancreatitis
Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction.
Pancreatitis
Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.
Pancreatitis
Human pancreatic secretory trypsin inhibitor in the assessment of the severity of acute pancreatitis. A comparison with C-reactive protein.
Pancreatitis
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Pancreatitis
Hypothyroidism with elevated pancreatic amylase and lipase without clinical symptoms: A case report.
Pancreatitis
Identification of a novel pancreatitis-associated missense mutation, R116C, in the human cationic trypsinogen gene (PRSS1).
Pancreatitis
Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.
Pancreatitis
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Pancreatitis
Immune-compromised state in the rat pancreas after chronic alcohol exposure: the role of peroxisome proliferator-activated receptor gamma.
Pancreatitis
Immunoenzymometric determination of trypsin/alpha 1-protease inhibitor complex in plasma of rats with experimental pancreatitis.
Pancreatitis
Immunohistochemical localization of trypsinogen and trypsin in acute and chronic pancreatitis.
Pancreatitis
Immunoreactive forms of cationic trypsin in plasma and ascitic fluid of dogs in experimental pancreatitis.
Pancreatitis
Immunoreactive trypsin in acute pancreatitis: elevated levels do not correlate with hyperamylasaemia.
Pancreatitis
Immunoreactive trypsins in sera from dogs before and after induction of experimental pancreatitis.
Pancreatitis
Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas.
Pancreatitis
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis.
Pancreatitis
Impaired mononuclear phagocyte function in patients with severe acute pancreatitis: evidence from studies of plasma clearance of trypsin and monocyte phagocytosis.
Pancreatitis
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
Pancreatitis
In acute pancreatitis the decrease of villous activity, the damage of the intestinal mucosa might be induced by agents produced during pancreatitis or by trypsin.
Pancreatitis
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Pancreatitis
Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation.
Pancreatitis
Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
Pancreatitis
Increased serum trypsin and elastase-1 levels in patients undergoing L-asparaginase therapy.
Pancreatitis
Increased serum trypsinogen 2 and trypsin 2-1 antitrypsin complex values identify endoscopic retrograde cholangiopancreatography (ERCP)-induced pancreatitis with high accuracy.
Pancreatitis
Increased serum trypsinogen 2 and trypsin 2-alpha 1 antitrypsin complex values identify endoscopic retrograde cholangiopancreatography induced pancreatitis with high accuracy.
Pancreatitis
Influence of hormonal stimulation by caerulein on acute experimental pancreatitis in the rat.
Pancreatitis
Influence of intraluminal trypsin activity on the course of acute experimental pancreatitis.
Pancreatitis
Influence of the human pancreatic secretory trypsin inhibitor on trypsin-induced C3 and kininogen cleavage: an in vitro study.
Pancreatitis
Influence of trypsin-induced acute pancreatitis on survival and energy state of isolated acinar cells from rat pancreas.
Pancreatitis
Inhibition of cathepsin B does not affect the intracellular activation of trypsinogen by cerulein hyperstimulation in isolated rat pancreatic acinar cells.
Pancreatitis
Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury.
Pancreatitis
Inhibition of human pancreatic proteinases by human plasma alpha2-antiplasmin and antithrombin.
Pancreatitis
Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis.
Pancreatitis
Inhibitory effect of human urinary trypsin inhibitor (urinastatin) on lysosomal thiol proteinases.
Pancreatitis
Inhibitory effects of daidzein and genistein on trypsin: Insights from spectroscopic and molecular docking studies.
Pancreatitis
Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
Pancreatitis
Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats.
Pancreatitis
Intracellular trypsin induces pancreatic acinar cell death but not NF-{kappa}B activation.
Pancreatitis
Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis.
Pancreatitis
Intrapancreatic turnover of recombinant human pancreatic secretory trypsin inhibitor in experimental porcine pancreatitis.
Pancreatitis
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.
Pancreatitis
Involvement of tubular complexes in pancreatic regeneration after acute necrohemorrhagic pancreatitis.
Pancreatitis
K+-induced ion-exchanges trigger trypsin activation in pancreas acinar zymogen granules.
Pancreatitis
Keratin 8 Mutations Are Not Associated with Familial, Sporadic and Alcoholic Pancreatitis in a Population from the United States.
Pancreatitis
Kininogen level in clinical pancreatitis during treatment with trypsin inhibitor from bovine lung.
Pancreatitis
Lack of R117H mutation in the cationic trypsinogen gene in patients with tropical pancreatitis from Bangladesh.
Pancreatitis
Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis.
Pancreatitis
Local administration of human pancreatic secretory trypsin inhibitor prevents the development of experimental acute pancreatitis in rats and dogs.
Pancreatitis
Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany.
Pancreatitis
Localized necrohemorrhagic pancreatitis in the rat after pancreatic interstitial trypsin injection. Regressive pseudochronic lesions.
Pancreatitis
Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury.
Pancreatitis
Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.
Pancreatitis
Low-volume continuous hemodiafiltration with nafamostat mesilate increases trypsin clearance without decreasing plasma trypsin concentration in severe acute pancreatitis.
Pancreatitis
Lymphotoxin ? Receptor Signaling Promotes Development of Autoimmune Pancreatitis.
Pancreatitis
Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat.
Pancreatitis
Mechanism of acute pancreatitis exacerbation by enteral bile-pancreatic juice exclusion.
Pancreatitis
Melatonin attenuates the in?ammatory response via inhibiting the C/EBP homologous protein-mediated pathway in taurocholate-induced acute pancreatitis.
Pancreatitis
Membrane-bound ICAM-1 is upregulated by trypsin and contributes to leukocyte migration in acute pancreatitis.
Pancreatitis
Misfolding cationic trypsinogen variant p.L104P causes hereditary pancreatitis.
Pancreatitis
Molecular forms of immunoreactive pancreatic cationic trypsin in pancreatitis patient sera.
Pancreatitis
Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.
Pancreatitis
Monitoring serum tryptic activity and effect of trypsin inhibitor on rat acute pancreatitis.
Pancreatitis
Multifactorial Genesis of Pancreatitis in Primary Hyperparathyroidism: Evidence for "Protective" (PRSS2) and "Destructive" (CTRC) Genetic Factors.
Pancreatitis
Multisite mutations of the PRSS1 gene in a Chinese patient with chronic pancreatitis.
Pancreatitis
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Pancreatitis
Mutation analysis of the cystic fibrosis and cationic trypsinogen genes in patients with alcohol-related pancreatitis.
Pancreatitis
Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice.
Pancreatitis
Mutational analysis of the pancreatic secretory trypsin inhibitor gene in familial and juvenile pancreatitis in Japan.
Pancreatitis
Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis.
Pancreatitis
Mutations in anionic trypsinogen gene are not associated with tropical calcific pancreatitis.
Pancreatitis
Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis.
Pancreatitis
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis.
Pancreatitis
Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis.
Pancreatitis
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Pancreatitis
Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis.
Pancreatitis
Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis.
Pancreatitis
Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis.
Pancreatitis
Mutations of the cationic trypsinogen gene in patients with hereditary pancreatitis.
Pancreatitis
Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis.
Pancreatitis
Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
Pancreatitis
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis.
Pancreatitis
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis.
Pancreatitis
Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis.
Pancreatitis
Novel mutation and polymorphism of PRSS1 gene in the Chinese patients with hereditary pancreatitis and chronic pancreatitis.
Pancreatitis
On the role of the pancreatic secretory trypsin inhibitor as an inactivator of trypsin-alpha 2-macroglobulin complexes in acute pancreatitis.
Pancreatitis
Origin and implication of the hereditary pancreatitis-associated N21I mutation in the cationic trypsinogen gene.
Pancreatitis
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis.
Pancreatitis
Overexpression of Smad6 Exacerbates Pancreatic Fibrosis in Murine Caerulein-Induced Chronic Pancreatic Injuries.
Pancreatitis
Pancreas-specific SNAP23 depletion prevents pancreatitis by attenuating pathological basolateral exocytosis and formation of trypsin-activating autolysosomes.
Pancreatitis
Pancreatic acinar cell function and morphology in rats chronically fed an ethanol diet.
Pancreatitis
Pancreatic proteases in serum induce leukocyte-endothelial adhesion and pancreatic microcirculatory failure.
Pancreatitis
Pancreatic secretory proteins in sera from rats before and after induction of experimental pancreatitis.
Pancreatitis
Pancreatic secretory trypsin inhibitor (SPINK1) gene mutations in patients with acute pancreatitis.
Pancreatitis
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Pancreatitis
Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1? in the pancreas.
Pancreatitis
Pancreatitis in fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene.
Pancreatitis
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Pancreatitis
Pancreatitis-induced increase in lung vascular permeability. Protective effect of Trasylol.
Pancreatitis
PAR2 exerts local protection against acute pancreatitis via modulation of MAP kinase and MAP kinase phosphatase signaling.
Pancreatitis
Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis.
Pancreatitis
Pathomorphological analysis of the pancreaticoduodenal organs in experimental pancreonecrosis induced by trypsin injection.
Pancreatitis
Peritoneal absorption of pancreatic enzymes in bile-induced acute pancreatitis in dogs.
Pancreatitis
Peritoneal lavage efficiently eliminates protease-alpha-2-macroglobulin complexes and components of the contact system from the peritoneal cavity in patients with severe acute pancreatitis.
Pancreatitis
Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors.
Pancreatitis
Plasma beta-endorphin and the effect of naloxone on hemodynamic changes during experimental acute pancreatitis in dogs.
Pancreatitis
Plasma levels of elastase, trypsin and their inhibitors in bile induced pancreatitis in the dog.
Pancreatitis
Polyamine catabolism in relation to trypsin activation and apoptosis in experimental acute pancreatitis.
Pancreatitis
Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis.
Pancreatitis
Prevention of acute experimental pancreatitis in rats and dogs by intraduodenal infusion of a synthetic trypsin inhibitor.
Pancreatitis
Prevention of experimental acute pancreatitis by intraduodenal trypsin inhibitor in rat.
Pancreatitis
Preventive effects of ulinastatin on complications related to pancreaticoduodenectomy: A Consort-prospective, randomized, double-blind, placebo-controlled trial.
Pancreatitis
Proinflammatory role of trypsin and protease-activated receptor-2 in a rat model of acute pancreatitis.
Pancreatitis
Prostacyclin (PGI2) stabilises hepatic lysosomes during acute experimental pancreatitis in dogs.
Pancreatitis
Prostaglandin F2 alpha and prostacyclin tissue levels in early phases of trypsin-induced acute pancreatitis in rats.
Pancreatitis
Protease activation during in vivo pancreatitis is dependent on calcineurin activation.
Pancreatitis
Protease Activation during in vivo Pancreatitis is Dependent upon Calcineurin Activation.
Pancreatitis
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis.
Pancreatitis
Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion.
Pancreatitis
Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells.
Pancreatitis
Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Pancreatitis
Protection against acute pancreatitis by activation of protease-activated receptor-2.
Pancreatitis
Protection from pancreatitis by the zymogen granule membrane protein integral membrane-associated protein-1.
Pancreatitis
Protective effect of a pancreatic elastase inhibitor against a variety of acute pancreatitis in rats.
Pancreatitis
Protective effect of human pancreatic secretory trypsin inhibitor on cerulein-induced acute pancreatitis in rats.
Pancreatitis
Protective effect of the combined treatment of pancreatic and neutrophil elastase inhibitors on acute pancreatitis elicited by lipopolysaccharide in rats given intraductal injection of taurocholate plus trypsin.
Pancreatitis
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Pancreatitis
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Pancreatitis
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Pancreatitis
Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
Pancreatitis
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
Pancreatitis
Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase.
Pancreatitis
Purification and some properties of a low molecular weight trypsin inhibitor from acute pancreatitis urine.
Pancreatitis
R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis.
Pancreatitis
Radioimmunoreactive serum elastase levels and histologic changes during experimental pancreatitis in rats.
Pancreatitis
Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy.
Pancreatitis
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Pancreatitis
Relation of alpha 2-macroglobulin and other antiproteases to the clinical features of acute pancreatitis.
Pancreatitis
Relationship between enteric microecologic dysbiosis and bacterial translocation in acute necrotizing pancreatitis.
Pancreatitis
Retardation of the progress of experimental pancreatitis with trypsin inhibitors.
Pancreatitis
Rhubarb combined with trypsin inhibitor for severe acute pancreatitis: A systematic review and meta-analysis.
Pancreatitis
Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants.
Pancreatitis
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.
Pancreatitis
Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis.
Pancreatitis
Role of macrophage migration inhibitory factor in acute lung injury in mice with acute pancreatitis complicated by endotoxemia.
Pancreatitis
Role of oxygen-derived free radicals in protease activation after pancreas transplantation in the pig.
Pancreatitis
Role of reactive oxygen metabolites in early cardiopulmonary changes of acute hemorrhagic pancreatitis.
Pancreatitis
Role of Ulinastatin, a trypsin inhibitor, in severe acute pancreatitis in critical care setting: A retrospective analysis.
Pancreatitis
Roles of Autophagy and Pancreatic Secretory Trypsin Inhibitor in Trypsinogen Activation in Acute Pancreatitis.
Pancreatitis
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Pancreatitis
Screening for human cationic trypsinogen (PRSS1) and trypsinogen inhibitor gene (SPINK1) mutations in a Finnish family with hereditary pancreatitis.
Pancreatitis
Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis?
Pancreatitis
Selected biochemical parameters and ultrastructural picture of pancreas due to Ulinastatin treatment of experimental acute pancreatitis.
Pancreatitis
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
Pancreatitis
Sequential connective matrix changes in experimental acute pancreatitis. An immunohistochemical and biochemical assessment in the rat.
Pancreatitis
Serial alterations in the forms of immunoreactive pancreatic cationic trypsin in plasma from patients with acute pancreatitis.
Pancreatitis
Serum complex of trypsin 2 and alpha 1 antitrypsin as diagnostic and prognostic marker of acute pancreatitis: clinical study in consecutive patients.
Pancreatitis
Serum phospholipase A2, immunoreactive trypsin, and trypsin inhibitors during human acute pancreatitis.
Pancreatitis
Serum Serine Peptidase Inhibitor Kazal-Type 1, Trypsinogens 1 to 3, and Complex of Trypsin 2 and ?1-Antitrypsin in the Diagnosis of Severe Acute Pancreatitis.
Pancreatitis
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Pancreatitis
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Pancreatitis
Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis.
Pancreatitis
Site-specific therapeutic effects of protease inhibitors: effect of route of administration in experimental pancreatitis.
Pancreatitis
Soybean trypsin inhibitor and cerulein accelerate recovery of cerulein-induced pancreatitis in rats.
Pancreatitis
Specific immunoassay reveals increased serum trypsinogen 3 in acute pancreatitis.
Pancreatitis
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
Pancreatitis
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
Pancreatitis
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.
Pancreatitis
Strong evidence that the N21I substitution in the cationic trypsinogen gene causes disease in hereditary pancreatitis.
Pancreatitis
Studies of pure pancreatic secretions in chronic alcoholic subjects without pancreatic insufficiency.
Pancreatitis
Studies on the kallikrein-kinin system in plasma and peritoneal fluid during experimental pancreatitis.
Pancreatitis
Sudden blindness in acute pancreatitis. Possible role of complement-induced retinal leukoembolization.
Pancreatitis
Survival and morphology of isolated pancreatic acinar cells from rats with induced acute pancreatitis are not improved with anti-inflammatory drugs.
Pancreatitis
Systematic review and meta-analysis of the efficacy of trypsin inhibitors in patients with severe pancreatitis.
Pancreatitis
Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.
Pancreatitis
Temporary pseudochronic lesions during the recovery of acute necrohemorrhagic pancreatitis in rabbits.
Pancreatitis
The cholecystokinin receptor antagonist L-364,718 reduces taurocholate-induced pancreatitis in rats.
Pancreatitis
THE EFFECT OF A TRYPSIN INHIBITOR, TRASYLOL, ON THE COURSE OF BILE AND TRYPSIN-INDUCED PANCREATITIS IN DOGS.
Pancreatitis
The effect of ERCP on circulating pancreatic enzymes and pancreatic protease inhibitors.
Pancreatitis
The effect of interleukin-6 on bacterial translocation in acute canine pancreatitis.
Pancreatitis
The effect of peritoneal dialysis with and without aprotinin on acute experimental pancreatitis in rats.
Pancreatitis
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.
Pancreatitis
The effects upon blood coagulation in dogs of experimentally induced pancreatitis and the infusion of pancreatic juice.
Pancreatitis
The elimination of trypsin--alpha-macroglobulin complexes from the blood circulation in pigs during acute pancreatitis and after massive intravenous trypsin infusion.
Pancreatitis
The Guinea pig pancreas secretes a single trypsinogen isoform, which is defective in autoactivation.
Pancreatitis
The influence of caecostomy and colonic irrigation on pathophysiology and prognosis in acute experimental pancreatitis.
Pancreatitis
The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis.
Pancreatitis
The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis.
Pancreatitis
The pancreatitis-associated protein in hereditary and chronic alcoholic pancreatitis.
Pancreatitis
The pathobiochemistry of hereditary pancreatitis: studies on recombinant human cationic trypsinogen.
Pancreatitis
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
Pancreatitis
The protective effect of the trypsin inhibitor urinastatin on cerulein-induced acute pancreatitis in rats.
Pancreatitis
The protective effects of long-acting recombinant human pancreatic secretory trypsin inhibitor (R44S-PSTI) in a rat model of cerulein-induced pancreatitis.
Pancreatitis
The proteinases and proteinase inhibitors in the peritoneal exudate during acute experimental pancreatitis in the rat.
Pancreatitis
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.
Pancreatitis
The Relationship between Trypsin/Calcitonin Gene Related Peptide (CGRP) in Serum and Acute Pancreatitis (AP).
Pancreatitis
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Pancreatitis
The role of calcium-binding protein S100g (CalbindinD-9K) and annexin A10 in acute pancreatitis.
Pancreatitis
THE ROLE OF PANCREATIC ENZYMES IN THE PATHOGENESIS OF ACUTE PANCREATITIS. III.COMPARISON OF THE PATHOLOGIC AND BIOCHEMICAL CHANGES IN THE CANINE PANCREAS TO INTRADUCTAL INJECTION WITH BILE AND WITH TRYPSIN.
Pancreatitis
The role of pancreatic enzymes in the pathogenesis of acute pancreatitis. The failure of a trypsin inhibitor: benzethonium chloride to prevent experimental acute pancreatitis.
Pancreatitis
The role of trypsin and of bile salts in the pathogenesis of acute pancreatitis.
Pancreatitis
The role of trypsin, trypsin inhibitor, and trypsin receptor in the onset and aggravation of pancreatitis.
Pancreatitis
The significance of reflux of trypsin and bile in the pathogenesis of human pancreatitis.
Pancreatitis
The spectrum of complications of hereditary pancreatitis. Is this a model for future gene therapy?
Pancreatitis
The therapeutic effect of a new synthetic protease inhibitor (E-3123) on hemodynamic changes during experimental acute pancreatitis in dogs.
Pancreatitis
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
Pancreatitis
The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families.
Pancreatitis
The vasoactive properties of ascitic fluid in acute pancreatitis in a porcine model.
Pancreatitis
Therapeutic efficacy of an antineutrophil monoclonal antibody, Urge-8, against acute necrotizing pancreatitis in rats.
Pancreatitis
Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.
Pancreatitis
Toxic products in hemorrhagic ascitic fluid generated during experimental acute hemorrhagic pancreatitis in dogs and a treatment which reduces their effect.
Pancreatitis
Transforming growth factor-beta1, interleukin-10 and interferon-gamma cytokine polymorphisms in patients with hereditary, familial and sporadic chronic pancreatitis.
Pancreatitis
Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice.
Pancreatitis
Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations.
Pancreatitis
Trypsin activation peptide (TAP) in acute pancreatitis: from pathophysiology to clinical usefulness.
Pancreatitis
Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H.
Pancreatitis
Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury.
Pancreatitis
Trypsin and splanchnic protein turnover during feeding and fasting in human subjects.
Pancreatitis
Trypsin encoding PRSS1-PRSS2 variation influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.
Pancreatitis
Trypsin inhibitor and proteolytic enzyme activity in dogs after ethionine-induced pancreatitis.
Pancreatitis
Trypsin is the culprit of multiple organ injury with severe acute pancreatitis.
Pancreatitis
TRYPSIN RELEASE, KININ PRODUCTION, AND SHOCK; RELATIONSHIP IN EXPERIMENTAL AND HUMAN PANCREATITIS.
Pancreatitis
Trypsin(ogen) content of pancreatic calculi in chronic calcified pancreatitis in man.
Pancreatitis
Trypsin-based laboratory methods and carboxypeptidase activation peptide in acute pancreatitis.
Pancreatitis
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Pancreatitis
Trypsinogen gene mutations in patients with chronic or recurrent acute pancreatitis.
Pancreatitis
Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
Pancreatitis
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases.
Pancreatitis
Two novel severe mutations in the pancreatic secretory trypsin inhibitor gene (SPINK1) cause familial and/or hereditary pancreatitis.
Pancreatitis
Ulinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells.
Pancreatitis
Ulinastatin Exerts Synergistic Effects with Taxotere and Inhibits Invasion and Metastasis of Breast Cancer by Blocking Angiogenesis and the Epithelial-Mesenchymal Transition.
Pancreatitis
Ulinastatin suppresses lipopolysaccharide-induced prostaglandin E2 synthesis and nitric oxide production through the downregulation of nuclear factor??B in BV2 mouse microglial cells.
Pancreatitis
Uncertainties in the classification of human cationic trypsinogen (PRSS1) variants as hereditary pancreatitis-associated mutations.
Pancreatitis
Urinary enzymes excretion in pancreatic diseases. Clinical role and pathophysiological considerations.
Pancreatitis
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Pancreatitis
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Pancreatitis
Urinary trypsin inhibitor attenuates liver enzyme elevation after liver resection.
Pancreatitis
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Pancreatitis
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
Pancreatitis
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
Pancreatitis
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
Pancreatitis
Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis.
Pancreatitis
Usefulness of determination of serum immunoreactive pancreatic phospholipase A2 content for early identification of severe acute pancreatitis.
Pancreatitis
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
Pancreatitis
[A case of R122H mutation of cationic trypsinogen gene in a pediatric patient with hereditary pancreatitis complicated by pseudocyst and hemosuccus pancreaticus]
Pancreatitis
[Absorption of trypsin and its inhibitors from the abdominal cavity in experimental acute pancreatitis]
Pancreatitis
[Acute pancreatitis and the lung--a comparative study with lung lesions induced by trypsin infusion]
Pancreatitis
[Acute pancreatitis induced by bile trypsin: structural and ultrastructural study]
Pancreatitis
[An electron microscopical study on the pathogenesis of taurocholate-induced acute pancreatitis]
Pancreatitis
[An experimental study on curative effect of Chinese medicine qing yi tang in acute necrotizing pancreatitis]
Pancreatitis
[Analysis by means of pancreatozymin of the degree of parallelism of secretion of pancreatic enzymes in healthy persons and patients with chronic pancreatitis]
Pancreatitis
[APROPOS OF THE TREATMENT OF PANCREATITIS WITH TRYPSIN INHIBITORS. CRITICAL REMARKS.]
Pancreatitis
[Cationic trypsinogen gene mutation in patients with chronic idiopathic pancreatitis]
Pancreatitis
[Change in proteolytic enzymatic activity in the blood serum in children with chronic diseases of the digestive organs]
Pancreatitis
[Changes in blood enzyme activity and tumor necrosis factor level in the treatment of experimental pancreatitis with pentoxifylline]
Pancreatitis
[Changes in serum pancreatic enzymes and pancreatic secretory trypsin inhibitor in patients with severe acute pancreatitis]
Pancreatitis
[Defense mechanism to prevent ectopic activation of pancreatic digestive enzymes under physiological conditions and its breakdown in acute pancreatitis]
Pancreatitis
[Diagnostic usefulness and prognostic value of inhibitory capacity and other biochemical parameters of plasma in acute pancreatitis in humans]
Pancreatitis
[Diagnostic value of serum pancreatic secretory trypsin inhibitor (PSTI) in acute pancreatitis]
Pancreatitis
[Effect of 5-fluorouracil on the enzymatic activity of the pancreas and blood serum of rats with acute pancreatitis]
Pancreatitis
[Effect of protease inhibitors on the activity of trypsin and lipase in the pancreas and blood serum of rats in acute pancreatitis]
Pancreatitis
[Effect of trypsin and kallikrein (andecalin) on the activity of proteolytic enzymes and their inhibitors in acute experimental pancreatitis]
Pancreatitis
[Effects of bovine pancreatic polypeptide on phospholipase A and trypsin activities in pancreatic tissue in rats with acute pancreatitis]
Pancreatitis
[Effects of E-3123, a new protease inhibitor, on several protease activities and on experimental acute pancreatitis]
Pancreatitis
[Effects of several regulatory peptides on the functional activity of the pancreas in acute experimental pancreatitis]
Pancreatitis
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
Pancreatitis
[Examination of pancreatic function in children with special reference to the PABA-test (author's transl)]
Pancreatitis
[Experimental acute pancreatitis in rats and its histopathologic evolution in time. 3. Acute pancreatitis induced with trypsin inhibitors: zymofren and iniprol]
Pancreatitis
[Experimental acute pancreatitis in rats and its histopathologic evolution in time. II. Acute pancreatitis induced with different enzymes: trypsin, alphachymotrypsin, elastase, collagenase and lipase]
Pancreatitis
[Experimental studies on the significance of the measurement of serum pancreatic secretory trypsin inhibitor in acute pancreatitis]
Pancreatitis
[Genetic risk factors in pancreatic diseases--significance for general practice]
Pancreatitis
[Hemodynamic and microcirculatory changes in the liver in experimental acute pancreatitis of dogs]
Pancreatitis
[Hemostatic function and level of autoantibodies to trypsin and factor Xa in rats in experimental pancreatitis]
Pancreatitis
[Hereditary pancreatitis - a clinically relevant cause of pancreatic adenocarcinoma?]
Pancreatitis
[Hereditary pancreatitis caused by a new mutation in the trypsinogen gene. Report of a family]
Pancreatitis
[Hereditary pancreatitis is due to a mutation of the cationic trypsinogen gene]
Pancreatitis
[Hydrolysis by enteropeptidase of nonspecific (model) peptide sequences and possible physiological role of this phenomenon]
Pancreatitis
[Identical Variants Different Disease Course - Genetics of Chronic Pancreatitis].
Pancreatitis
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Pancreatitis
[IN VITRO AND IN VIVO STUDY OF A TRYPSIN INHIBITOR IN ACUTE PANCREATITIS: EXPERIMENTAL STUDY AND A REPORT OF ITS USE IN HUMAN CASE.]
Pancreatitis
[Increasing of the trypsin rate frequency in the blood serum in children with viral hepatitis].
Pancreatitis
[Inhibition of the secretion of endogenous insulin and trypsin by exogenous insulin and trypsin in the complex treatment of acute pancreatitis]
Pancreatitis
[Interaction of proteases and their inhibitors in the pathogenesis of pancreatitis]
Pancreatitis
[Light microscopy and autoradiography studies of the organization of trypsin pancreatitis]
Pancreatitis
[Method of determining trypsin and trypsinogen in a homogenate of animal pancreas in experimental pancreatitis]
Pancreatitis
[Mutations of the pancreatic secretory trypsin inhibitor. Is the cause of chronic pancreatitis now known?]
Pancreatitis
[On the possibility of causal modification of acute pancreatitis by inactivation of trypsin.]
Pancreatitis
[PANCREATIC JUICE SECRETION AND BEHAVIOR OF TRYPSIN IN EXPERIMENTAL ACUTE PANCREATITIS.]
Pancreatitis
[Pharmacological studies of FUT-175, nafamstat mesilate. II. Effects on experimental acute pancreatitis]
Pancreatitis
[Possibilities of determination of trypsin in the blood serum of patients with pancreatitis]
Pancreatitis
[Radioimmunoassay in the evaluation of pancreas function in chronic pancreatitis]
Pancreatitis
[Renal microcirculation in experimental acute pancreatitis of dogs--the effect of pancreatic protease inhibitor and dopamine]
Pancreatitis
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
Pancreatitis
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
Pancreatitis
[STUDIES ON THE EFFECTS OF A TRYPSIN INHIBITOR (TRASYLOL) ON ENZYME ACTIVITIES AND MORPHOLOGY IN TAUROCHOLATE AND CALCIPHYLAXIS PANCREATITIS OF THE RAT (A CONTRIBUTION TO THE PATHOGENESIS OF PANCREATITIS. II.)]
Pancreatitis
[Study of an optimal biological profile for demonstrating pancreatic involvement in acute abdominal syndrome]
Pancreatitis
[The diagnostic significance of pancreatic enzymes in the blood serum and urine in chronic pancreatitis]
Pancreatitis
[The diagnostic significance of soluble fibrin monomer complexes in exacerbated chronic recurrent pancreatitis]
Pancreatitis
[The efficacy of the combined use of 5-fluorouracil electrophoresis and magnetotherapy in experimental pancreatitis]
Pancreatitis
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis]
Pancreatitis
[The pathogenesis of infection complicated by acute necrotizing pancreatitis: an experimental study]
Pancreatitis
[The role of amylase in abdominal fluid in evaluating severity of acute pancreatitis and its prognosis]
Pancreatitis
[The serum enzymogram for the evaluation of the effectiveness of hemosorption in patients with acute destructive pancreatitis]
Pancreatitis
[The significance of trypsin, amylase and lipase activities in the blood serum for the differential,diagnosis of chronic pancreatitis and other diseases of the abdominal organs]
Pancreatitis
[The treatment of acute pancreatitis by blocking the pancreatic secretion with trypsin inactivators]
Pancreatitis
[The value of estimation of serum pancreatic elastase in experimental pancreatic disorders in rats]
Pancreatitis
[Therapeutic effects of human urinary trypsin inhibitor on acute experimental pancreatitis]
Pancreatitis
[Therapy with kallikrein and trypsin inhibitors, a part of the modern treatment of acute pancreatitis.]
Pancreatitis
[Three cases of hereditary pancreatitis in two households in the same family associated with R122H mutation in cationic trypsinogen gene]
Pancreatitis
[Trypsin and trypsin inhibitor level in the blood serum in various forms of acute pancreatitis]
Pancreatitis, Acute Hemorrhagic
Aprotinin and Na2CaEDTA in experimental hemorrhagic pancreatitis in pigs.
Pancreatitis, Acute Hemorrhagic
Effect of a new inhibitor of type II phospholipase A2 on experimental acute pancreatitis in rats.
Pancreatitis, Acute Hemorrhagic
Effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.
Pancreatitis, Acute Hemorrhagic
Effect of protease inhibitor FUT-175 on acute hemorrhagic pancreatitis in mice.
Pancreatitis, Acute Hemorrhagic
Effects of a new cholecystokinin antagonist, TS-941, on experimental acute pancreatitis in rats.
Pancreatitis, Acute Hemorrhagic
Failure of activated trypsin to cause experimental acute hemorrhagic pancreatitis.
Pancreatitis, Acute Hemorrhagic
Failure of Activated Trypsin to Cause Experimental Hemorrhagic Pancreatitis.
Pancreatitis, Acute Hemorrhagic
Methylprednisolone in acute canine hemorrhagic pancreatitis.
Pancreatitis, Acute Hemorrhagic
Prevention of increased pulmonary vascular permeability after pancreatitis by granulocyte depletion in sheep.
Pancreatitis, Acute Hemorrhagic
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.
Pancreatitis, Acute Hemorrhagic
Serum phospholipase A2, immunoreactive trypsin, and trypsin inhibitors during human acute pancreatitis.
Pancreatitis, Acute Hemorrhagic
Study of the effect of trypsin inhibitor in acute hemorrhagic pancreatitis in dogs.
Pancreatitis, Acute Hemorrhagic
The role of trypsin in the pathogenesis of acute hemorrhagic pancreatitis and the effect of an antitryptic agent in treatment.
Pancreatitis, Acute Hemorrhagic
Toxicity of hemorrhagic ascitic fluid associated with hemorrhagic pancreatitis.
Pancreatitis, Acute Hemorrhagic
TRYPSIN INHIBITOR IN ACUTE HEMORRHAGIC PANCREATITIS IN DOGS; EFFECT.
Pancreatitis, Acute Hemorrhagic
Use of crystalline soybean trypsin inhibitor in acute hemorrhagic pancreatitis in dogs.
Pancreatitis, Acute Hemorrhagic
[Evidence of the presence of trypsin in peripheral blood during acute hemorrhagic pancreatitis. Its role in the development of shock]
Pancreatitis, Acute Hemorrhagic
[Remarks on the trypsin activity of pancreatic juice during acute hemorrhagic pancreatitis treated with anti-enzymes.]
Pancreatitis, Acute Hemorrhagic
[The role of trypsin in the secondary manifestations of acute hemorrhagic pancreatitis]
Pancreatitis, Acute Necrotizing
A novel thermosensitive in-situ gel of gabexate mesilate for treatment of traumatic pancreatitis: An experimental study.
Pancreatitis, Acute Necrotizing
Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum.
Pancreatitis, Acute Necrotizing
Candesartan mediates microcirculation in acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
Cholinergic mediation of alcohol-induced experimental pancreatitis.
Pancreatitis, Acute Necrotizing
Continuous peritoneal dialysis in acute experimental pancreatitis in dogs. Effect of aprotinin in the dialysate medium.
Pancreatitis, Acute Necrotizing
Pancreatic fat necrosis and hemorrhagic necrosis as separate morphological and functional entities.
Pancreatitis, Acute Necrotizing
Relationship between enteric microecologic dysbiosis and bacterial translocation in acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.
Pancreatitis, Acute Necrotizing
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
[An experimental study on curative effect of Chinese medicine qing yi tang in acute necrotizing pancreatitis]
Pancreatitis, Acute Necrotizing
[Effect of hyperbaric oxygenation on experimental pancreas necrosis in pigs]
Pancreatitis, Acute Necrotizing
[Possibilities of the use of trypsinogen activation peptide in the pancreatic tissue in the diagnosis of pancreatic necrosis]
Pancreatitis, Acute Necrotizing
[Significance of bile and trypsin in the pathogenesis of acute pancreatic necrosis.]
Pancreatitis, Acute Necrotizing
[The pathogenesis of infection complicated by acute necrotizing pancreatitis: an experimental study]
Pancreatitis, Alcoholic
A review: acute and chronic effects of ethanol and alcoholic beverages on the pancreatic exocrine secretion in vivo and in vitro.
Pancreatitis, Alcoholic
Different responses of serum cationic trypsinogen to secretin and bombesin in normal subjects and patients with chronic alcoholic pancreatitis.
Pancreatitis, Alcoholic
Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.
Pancreatitis, Alcoholic
Keratin 8 Mutations Are Not Associated with Familial, Sporadic and Alcoholic Pancreatitis in a Population from the United States.
Pancreatitis, Alcoholic
Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis.
Pancreatitis, Chronic
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis.
Pancreatitis, Chronic
A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.
Pancreatitis, Chronic
A loss of function polymorphism (G191R) of anionic trypsinogen (PRSS2) confers protection against chronic pancreatitis.
Pancreatitis, Chronic
A loss-of-function p.G191R variant in the anionic trypsinogen (PRSS2) gene in Japanese patients with pancreatic disorders.
Pancreatitis, Chronic
A novel A121T mutation in human cationic trypsinogen associated with hereditary pancreatitis: functional data indicating a loss-of-function mutation influencing the R122 trypsin cleavage site.
Pancreatitis, Chronic
A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.
Pancreatitis, Chronic
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis.
Pancreatitis, Chronic
A study of the clinical utility of a 20-minute secretin-stimulated endoscopic pancreas function test and performance according to clinical variables.
Pancreatitis, Chronic
Absence of mesotrypsinogen gene (PRSS3) copy number variations in patients with chronic pancreatitis.
Pancreatitis, Chronic
Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis.
Pancreatitis, Chronic
Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis.
Pancreatitis, Chronic
Association of a new cationic trypsinogen gene mutation (V39A) with chronic pancreatitis in an Italian family.
Pancreatitis, Chronic
Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.
Pancreatitis, Chronic
Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.
Pancreatitis, Chronic
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Pancreatitis, Chronic
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
Pancreatitis, Chronic
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Pancreatitis, Chronic
Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation.
Pancreatitis, Chronic
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Pancreatitis, Chronic
Chronic pancreatitis resulting from genetic mutations in trypsin and trypsin inhibitors.
Pancreatitis, Chronic
Chronic pancreatitis with alpha 1-antitrypsin deficiency: from uncontrolled trypsin activation?
Pancreatitis, Chronic
Chronic pancreatitis: controversies in etiology, diagnosis and treatment.
Pancreatitis, Chronic
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
Pancreatitis, Chronic
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Pancreatitis, Chronic
Clinical significance of serum pancreatic enzymes in the quiescent phase of chronic pancreatitis.
Pancreatitis, Chronic
Comparative study of serum trypsin levels and pancreatic exocrine function in chronic pancreatitis.
Pancreatitis, Chronic
Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.
Pancreatitis, Chronic
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Pancreatitis, Chronic
Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Pancreatitis, Chronic
Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis.
Pancreatitis, Chronic
Detection of a large genomic deletion in the pancreatic secretory trypsin inhibitor (SPINK1) gene.
Pancreatitis, Chronic
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.
Pancreatitis, Chronic
Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice.
Pancreatitis, Chronic
Different responses of serum cationic trypsinogen to secretin and bombesin in normal subjects and patients with chronic alcoholic pancreatitis.
Pancreatitis, Chronic
Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.
Pancreatitis, Chronic
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Pancreatitis, Chronic
Effect of bombesin on serum immunoreactive trypsin in healthy subjects and in patients with chronic pancreatitis.
Pancreatitis, Chronic
Effect of secretin upon the levels of pancreatic enzymes in blood serum.
Pancreatitis, Chronic
Elastase-1 vs trypsin, lipase and amylase serum levels in pancreatic diseases.
Pancreatitis, Chronic
Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice.
Pancreatitis, Chronic
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Pancreatitis, Chronic
Fractional urinary clearance of immunoreactive lipase in chronic pancreatic disease.
Pancreatitis, Chronic
From acute to chronic pancreatitis: the role of mutations in the pancreatic secretory trypsin inhibitor gene.
Pancreatitis, Chronic
Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene.
Pancreatitis, Chronic
Gene Conversion between Cationic Trypsinogen (PRSS1) and the Pseudogene Trypsinogen 6 (PRSS3P2) in Patients with Chronic Pancreatitis.
Pancreatitis, Chronic
Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.
Pancreatitis, Chronic
Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.
Pancreatitis, Chronic
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis.
Pancreatitis, Chronic
Genetic risk in chronic pancreatitis: the misfolding-dependent pathway.
Pancreatitis, Chronic
Germline mutations in CFTR and PSTI genes in chronic pancreatitis patients.
Pancreatitis, Chronic
Hereditary pancreatitis: clinical characteristics and diagnostic criteria in Japan.
Pancreatitis, Chronic
Hereditary, familial, and idiopathic chronic pancreatitis are not associated with polymorphisms in the tumor necrosis factor alpha (TNF-alpha) promoter region or the TNF receptor 1 (TNFR1) gene.
Pancreatitis, Chronic
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
Pancreatitis, Chronic
Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis.
Pancreatitis, Chronic
Hydrogen breath test with glucose in exocrine pancreatic insufficiency.
Pancreatitis, Chronic
Immunohistochemical localization of trypsinogen and trypsin in acute and chronic pancreatitis.
Pancreatitis, Chronic
In silico prioritization and further functional characterization of SPINK1 intronic variants.
Pancreatitis, Chronic
Increased secretion of the pancreatic secretory trypsin inhibitor (PSTI-I, monitor peptide) during development of chronic pancreatitis in the WBN/Kob rat.
Pancreatitis, Chronic
Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
Pancreatitis, Chronic
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.
Pancreatitis, Chronic
Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death.
Pancreatitis, Chronic
Is genetic analysis helpful for diagnosing chronic pancreatitis in its early stage?
Pancreatitis, Chronic
Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany.
Pancreatitis, Chronic
Low Serum Trypsin Levels Predict Deep Pancreatic Cannulation Failure During Endoscopic Retrograde Cholangiopancreatography in Patients With Symptomatic Obstructive Chronic Pancreatitis.
Pancreatitis, Chronic
Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.
Pancreatitis, Chronic
Metastatic pancreatic adenocarcinoma associated with chronic calcific pancreatitis and a heterozygous SPINK1 N34S mutation.
Pancreatitis, Chronic
Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis.
Pancreatitis, Chronic
Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation.
Pancreatitis, Chronic
Molecular size distribution of immunoreactive trypsin and renal tubular dysfunction: role in trypsin plasma-urine transfer.
Pancreatitis, Chronic
Molecular understanding of chronic pancreatitis: a perspective on the future.
Pancreatitis, Chronic
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion.
Pancreatitis, Chronic
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Pancreatitis, Chronic
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Pancreatitis, Chronic
Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis.
Pancreatitis, Chronic
Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice.
Pancreatitis, Chronic
Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic chronic pancreatitis.
Pancreatitis, Chronic
Mutational analysis of the pancreatic secretory trypsin inhibitor gene in familial and juvenile pancreatitis in Japan.
Pancreatitis, Chronic
Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants.
Pancreatitis, Chronic
Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis.
Pancreatitis, Chronic
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis.
Pancreatitis, Chronic
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Pancreatitis, Chronic
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis.
Pancreatitis, Chronic
Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis.
Pancreatitis, Chronic
Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis.
Pancreatitis, Chronic
Mutations of the pancreatic secretory trypsin inhibitor (PSTI) gene in idiopathic chronic pancreatitis.
Pancreatitis, Chronic
Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
Pancreatitis, Chronic
Never conclude with a negative result, explore all possibilities before changing your hypothesis. An interview with Dr. Catherine Figarella, former Director Groupe de Recherche sur les Glandes Exocrines, Faculté de Médecine, Marseille, France; Active Member of the Board of the French Cystic Fibrosis Association: 'Vaincre la Mucoviscidose'. Interview by Martín E. Fernández-Zapico.
Pancreatitis, Chronic
Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis.
Pancreatitis, Chronic
Pancreatic secretion of zinc and copper in normal subjects and in patients with chronic pancreatitis.
Pancreatitis, Chronic
Pancreatic secretory trypsin inhibitor (SPINK1) gene mutations in patients with acute pancreatitis.
Pancreatitis, Chronic
Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1? in the pancreas.
Pancreatitis, Chronic
Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis.
Pancreatitis, Chronic
Physiological evaluation of the severity of pancreatic exocrine dysfunction during endoscopy.
Pancreatitis, Chronic
Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Pancreatitis, Chronic
Protection against chronic pancreatitis and pancreatic fibrosis in mice overexpressing pancreatic secretory trypsin inhibitor.
Pancreatitis, Chronic
PRSS1 and SPINK1 Mutations in Alcoholic and Idiopathic Chronic Pancreatitis.
Pancreatitis, Chronic
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
Pancreatitis, Chronic
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
Pancreatitis, Chronic
Quantitation of tryptic responses to endogenous and exogenous stimulation in chronic pancreatitis.
Pancreatitis, Chronic
Real-Time Label-Free Kinetics Monitoring of Trypsin-Catalyzed Ester Hydrolysis by a Nanopore Sensor.
Pancreatitis, Chronic
Relation between serum cathodic trypsinogen levels and exocrine pancreatic function.
Pancreatitis, Chronic
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Pancreatitis, Chronic
Relationship of basal and postprandial intraduodenal bile acid concentrations and plasma cholecystokinin levels with abdominal pain in patients with chronic pancreatitis.
Pancreatitis, Chronic
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Pancreatitis, Chronic
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Pancreatitis, Chronic
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Pancreatitis, Chronic
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Pancreatitis, Chronic
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
Pancreatitis, Chronic
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Pancreatitis, Chronic
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
Pancreatitis, Chronic
Serum immunoreactive trypsin after secretin stimulation in chronic pancreatitis.
Pancreatitis, Chronic
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Pancreatitis, Chronic
Serum immunoreactive trypsin response to secretin injection in patients with chronic pancreatitis.
Pancreatitis, Chronic
Serum immunoreactive trypsin, pancreatic polypeptide, and pancreatic isoamylase as diagnostic tests for chronic pancreatitis.
Pancreatitis, Chronic
Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis.
Pancreatitis, Chronic
SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent.
Pancreatitis, Chronic
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
Pancreatitis, Chronic
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.
Pancreatitis, Chronic
The A16V signal peptide cleavage site mutation in the cationic trypsinogen gene and chronic pancreatitis.
Pancreatitis, Chronic
The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.
Pancreatitis, Chronic
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
Pancreatitis, Chronic
The Prevalence of Cationic Trypsinogen (PRSS1) and Serine Protease Inhibitor, Kazal Type 1 (SPINK1) Gene Mutations in Polish Patients with Alcoholic and Idiopathic Chronic Pancreatitis.
Pancreatitis, Chronic
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Pancreatitis, Chronic
The spectrum of complications of hereditary pancreatitis. Is this a model for future gene therapy?
Pancreatitis, Chronic
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Pancreatitis, Chronic
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Pancreatitis, Chronic
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
Pancreatitis, Chronic
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Pancreatitis, Chronic
Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation.
Pancreatitis, Chronic
Two novel severe mutations in the pancreatic secretory trypsin inhibitor gene (SPINK1) cause familial and/or hereditary pancreatitis.
Pancreatitis, Chronic
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Pancreatitis, Chronic
Viscosity and trypsin activity of pure pancreatic juice in chronic pancreatitis.
Pancreatitis, Chronic
[A case of chronic pancreatitis in a young woman with the cationic trypsinogen (PRSS1) gene mutation]
Pancreatitis, Chronic
[Chronic pancreatitis--pancreas cancer: influence of genetic factors]
Pancreatitis, Chronic
[Clinical implications of genetic risk factors of chronic pancreatitis]
Pancreatitis, Chronic
[Concentration of trypsin and C-peptide in the sera of patients with chronic pancreatitis]
Pancreatitis, Chronic
[Diagnostic significance of pancreatic serum-enzyme patterns after stimulation with secretin in chronic pancreatitis (author's transl)]
Pancreatitis, Chronic
[Effect of pancreatic secretory trypsin gene mutations on the development of chronic pancreatitis].
Pancreatitis, Chronic
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
Pancreatitis, Chronic
[Evaluation of the vegetable oil taken up into the duodenum as a factor in pancreozymin liberation in healthy persons and in digestive organ diseases]
Pancreatitis, Chronic
[Genetic risk factors in pancreatic diseases--significance for general practice]
Pancreatitis, Chronic
[Immunoreactive trypsin in the blood serum of patients with endogenous hypercorticism]
Pancreatitis, Chronic
[Mutations of SPINK1 and PRSS1 gene in Korean patients with chronic pancreatitis]
Pancreatitis, Chronic
[Mutations of the pancreatic secretory trypsin inhibitor. Is the cause of chronic pancreatitis now known?]
Pancreatitis, Chronic
[Radio-immunologic measurement of trypsin in chronic pancreatitis. Preliminary results]
Pancreatitis, Chronic
[Role of cationic trypsinogen gene (PRSS-gene) mutations in the pathogenesis of chronic pancreatitis]
Pancreatitis, Chronic
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
Pancreatitis, Chronic
[Study of an optimal biological profile for demonstrating pancreatic involvement in acute abdominal syndrome]
Pancreatitis, Chronic
[The effect of a protein-rich diet on the trypsin activity in the blood serum of patients with chronic pancreatitis]
Pancreatitis, Chronic
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis]
Pancreatitis, Chronic
[The relation between the activity of trypsin and trypsin inhibitor in the serum and the status of the blood coagulation and anticoagulation system in patients with chronic pancreatitis]
Pancreatitis, Chronic
[The significance of trypsin, amylase and lipase activities in the blood serum for the differential,diagnosis of chronic pancreatitis and other diseases of the abdominal organs]
Pancreatitis, Chronic
[Trypsin and C-peptide concentration in the blood serum of patients with chronic pancreatitis]
Pancreatitis, Graft
Characterization of immunoreactive trypsin as a means of differentiating graft pancreatitis and allograft rejection after porcine pancreatic transplantation.
Paralysis
Differential gene expression profiles in the venom gland/sac of Eumenes pomiformis (Hymenoptera: Eumenidae).
Paramyxoviridae Infections
Effect of trypsin on reproduction of type 4 parainfluenza virus in Vero cell cultures under fluid overlay.
Paramyxoviridae Infections
Influence of trypsin on the infectivity and biological properties or parainfluenza type 2 type 2 (croup-associated) virus in Vero cells.
Paramyxoviridae Infections
Replication and plaque formation of parainfluenza viruses in an established line of monkey kidney cells.
Paramyxoviridae Infections
Sensitive plaque neutralization assay for parainfluenza virus types 1, 2, and 3 and respiratory syncytial virus.
Paramyxoviridae Infections
Susceptibility of continuous lines of monkey kidney cells to influenza and parainfluenza viruses in the presence of trypsin.
Parasitic Diseases
Induction of some digestive enzymes in the midgut of the sandfly Phlebotomus langeroni after sugar and blood meals.
Paratuberculosis
A technique for the purification of Mycobacterium paratuberculosis from the ileal mucosa of infected cattle.
Parkinson Disease
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Parotitis
[Acute hemorrhagic necrotic parotitis caused by injection of trypsin into the parotid duct; the preventive effect of upper cervical sympathectomy.]
Parotitis
[Trypsin treatment of protracted forms of nervous system lesions of parotitis etiology]
Pelvic Inflammatory Disease
Concentrations of tumor-associated trypsin inhibitor and C-reactive protein in serum in acute pelvic inflammatory disease.
Pemphigoid, Bullous
Pemphigoid, pemphigus and Pr antigens in adult human keratinocytes grown on nonviable substrates.
Pemphigoid, Bullous
The use of human pemphigoid autoantibodies to study the fate of epidermal basal cell hemidesmosomes after trypsin dissociation.
Pemphigus
Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation.
Pemphigus
Anti-epidermal-cell-surface pemphigus antibody detaches viable epidermal cells from culture plates by activation of proteinase.
Pemphigus
Corticosteroids, aurothioglucose and soybean trypsin inhibitor do not prevent pemphigus antibody-induced acantholysis in vitro.
Pemphigus
The pathogenic role of pemphigus antibodies and proteinase in epidermal acantholysis.
Peptic Ulcer
The mucous neck cell in the human gastric corpus: a distinctive, functional cell lineage.
Peptic Ulcer
[Cholecystokinin-pancreozymin excretion and the state of the blood trypsin inhibitor system after the surgical treatment of peptic ulcer]
Peptic Ulcer
[Effect of the alimentary factor on certain indices of the functional state of the pancreas in young peptic ulcer patients and atrophic gastritis patients]
Peptic Ulcer
[Kallikrein-kinin and trypsin inhibiting system of blood in patients with peptic ulcer]
Peptic Ulcer Perforation
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Periapical Diseases
Pulp Regeneration: Current Approaches, Challenges, and Novel Rejuvenating Strategies for an Aging Population.
Periodontal Diseases
Selective removal of human DNA from metagenomic DNA samples extracted from dental plaque.
Periodontal Diseases
The optimization of the BANA test as a screening instrument for gingivitis among subjects seeking dental treatment.
Periodontal Pocket
Inhibitory effect of serum globulins on the adhesion of Prevotella nigrescens to hydroxyapatite.
Periodontitis
Characterization of the trypsin-like enzymes of Porphyromonas gingivalis W83 using a radiolabelled active-site-directed inhibitor.
Periodontitis
Influence of anticholinergic drugs on the development of an experimental periodontitis model.
Periodontitis
Reflectance method for simple determination of proteinase activity in microliter samples of a complex serum-like fluid.
Periodontitis
Salivary collagenase. Origin, characteristics and relationship to periodontal health.
Periodontitis
Trypsin, T. denticola and P. gingivalis levels as diagnostic markers for periodontitis.
Periodontitis
[The influence of electrophoresis on the penetration and distribution of trypsin into dental tissues and periodontium in experimental periodontitis (radioisotope studies)]
Peripheral Arterial Disease
[Study of cantharides blister fluid in the analysis of the mechanism of action of trypsin in the treatment of chronic peripheral arterial diseases.]
Peripheral Vascular Diseases
Clinical studies on the use of parenteral trypsin and chymotrypsin in peripheral vascular disease.
Peripheral Vascular Diseases
Trypsin in peripheral vascular diseases; review and report on treatment of 210 patients.
Peripheral Vascular Diseases
Trypsin in the treatment of local complications of peripheral vascular disease in diabetes mellitus.
Peritonitis
"Two-route chemotherapy" using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, combined with angiotensin II is effective against peritoneally disseminated cancer in rats.
Peritonitis
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Peritonitis
Experimental inquiry into the significance of trypsin in bile peritonitis, with particular reference to the human secretions.
Peritonitis
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
Peritonitis
[Absorption of trypsin and its inhibitors from the abdominal cavity in experimental peritonitis]
Peritonitis
[Effect of proteolytic enzymes on kanamycin pharmacokinetics in experimental suppurative infection]
Peritonitis
[The activity of trypsin and proteolytic inhibitors in complicated forms of appendicitis in children]
Peritonitis
[The protein components of the acid-soluble fraction of normal human blood plasma and in peritonitis patients]
Persistent Infection
In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription.
Persistent Infection
Viruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cells.
Photophobia
Spectroscopic study of trypsin, heat and triton X-100-induced denaturation of the chlorophyll-binding protein CP43.
Pick Disease of the Brain
Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes.
Pituitary Neoplasms
Estrogen-induced hyperplasia and neoplasia in the rat anterior pituitary gland. An immunohistochemical study.
Pituitary Neoplasms
The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transfer.
Plasmacytoma
Cultured mouse marrow stromal cell lines. II. Distinct subtypes differing in morphology, collagen types, myelopoietic factors, and leukemic cell growth modulating activities.
Plasmacytoma
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Pleural Effusion
Concentration of tumor-associated trypsin inhibitor (TATI) in pleural effusions.
Pleural Effusion
[Association of trypsin and chymotrypsin in pleural effusions of diverse etiology]
Pleural Effusion
[Tissue polypeptide antigen and tumor trypsin inhibitor in pleural effusions of various etiologies]
Pleurisy
Are proteases used as anti-inflammatory agents in reality accelerating the inflammatory process?
Pleurisy
Effects of an orally active non-peptide bradykinin B2 receptor antagonist, FR173657, on plasma exudation in rat carrageenin-induced pleurisy.
Pleurisy
Proteinase-activated receptor-4 plays a major role in the recruitment of neutrophils induced by trypsin or carrageenan during pleurisy in mice.
Pleurisy
Rat pleurisy induced by kaolin or croton oil: time course of fluid accumulation and white cell migration.
Pneumonia
A 2S Albumin from the Seed Cake of Ricinus communis Inhibits Trypsin and Has Strong Antibacterial Activity against Human Pathogenic Bacteria.
Pneumonia
A plant proteinase inhibitor from enterolobium contortisiliquum attenuates airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.
Pneumonia
Aflatoxin G1 induced TNF-?-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells.
Pneumonia
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Pneumonia
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Pneumonia
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Pneumonia
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Pneumonia
Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge.
Pneumonia
Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis.
Pneumonia
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Pneumonia
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
Pneumonia, Bacterial
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition.
Pneumonia, Pneumocystis
?-Glucans Are Masked but Contribute to Pulmonary Inflammation During Pneumocystis Pneumonia.
Pneumothorax
[A case of spontaneous pneumothorax with gas embolism in intratracheal trypsin instillation]
Pneumothorax
[Spontaneous pneumothorax with gas embolism during intratracheal administration of trypsin]
Poliomyelitis
Studies of the inactivation of poliomyelitis virus by formaldehyde; effect of initial virus concentration, of mechanical stirring during inactivation and of digestion with trypsin prior to initiation of inactivation.
Poliomyelitis, Bulbar
Aerosol trypsin in respiratory complications of bulbar poliomyelitis; report of a case.
Poliomyelitis, Bulbar
Atelectasis; physiopathology and treatment; special reference to its occurrence in bulbar poliomyelitis, and to a suggested therapeutic aid by the intrabronchial administration of trypsin.
Polycythemia
Postnatal development of liver and exocrine pancreas in polycythemic newborn infants.
Porcine Reproductive and Respiratory Syndrome
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
Pre-Eclampsia
The effect of severe pre-eclampsia on the pancreas: changes in the serum cationic trypsinogen and pancreatic amylase.
Pre-Eclampsia
Urinary trypsin inhibitor may have a protective effect on endothelial cells in preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Conformational changes of rBTI from buckwheat upon binding to trypsin: implications for the role of the P(8)' residue in the potato inhibitor I family.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Trypsin encoding PRSS1-PRSS2 variation influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Suppressive activity of protease inhibitors from buckwheat seeds against human T-acute lymphoblastic leukemia cell lines.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
Pregnancy Complications
Plasma PP13 and urinary GAGs/PGs as early markers of pre-eclampsia.
Premature Birth
Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract.
Prostatic Neoplasms
Conformational and biochemical analysis of the cyclic peptides which modulate serine protease activity.
Prostatic Neoplasms
Editorial comment on: Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells.
Prostatic Neoplasms
Identification and quantification of peptides and proteins secreted from prostate epithelial cells by unbiased liquid chromatography tandem mass spectrometry using goodness of fit and analysis of variance.
Prostatic Neoplasms
Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells.
Prostatic Neoplasms
Prostate-specific antigen and other prostate-derived proteases cleave IGFBP-3, but prostate cancer is not associated with proteolytically cleaved circulating IGFBP-3.
Prostatic Neoplasms
Proteolytic modification of swelling-activated Cl- current in LNCaP prostate cancer epithelial cells.
Prostatic Neoplasms
Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
Prostatic Neoplasms
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Prostatic Neoplasms
[Effect of intracellular trypsin on characteristics of voltage-dependent inactivation of chloride currents in prostatic cancer cells]
Protein Deficiency
Exocrine pancreatic function in protein-deficient patas monkeys studied by means of a test meal and an indirect pancreatic function test.
Protein Deficiency
[Response of the rat pancreas to the effects of secretin and pancreozymin under conditions of different nutrition]
Protein-Energy Malnutrition
Serum trypsin as measure of pancreatic exocrine function in children with protein calorie malnutrition.
Protein-Energy Malnutrition
[Comparative study of the effects of 2 types of protein-energy malnutrition followed by a balanced realimentation on trypsin and chymotrypsin activity of the pancreas and the pancreatic juice of the rat]
Protein-Energy Malnutrition
[Serum cationic trypsinogen: marker of exocrine pancreatic dysfunction in children with protein-calorie malnutrition]
Protein-Losing Enteropathies
Enteropathy-type T-cell lymphoma that was pathologically diagnosed as celiac disease.
Proteinuria
Antimicrobial gentamicin activity in the presence of exogenous protease inhibitor (Bowman-Birk inhibitor) in gentamicin-induced nephrotoxicity in rats.
Proteinuria
Effect of interaction between gentamicin and pyridoxal-5-phosphate on functional and metabolic parameters in kidneys of female Sprague-Dawley rats.
Proteinuria
Enhanced urinary trypsin inhibitory activity in gentamicin-induced nephrotoxicity in rats.
Proteinuria
Urinary cancer-related protein EDC1 and serum inter-alpha trypsin inhibitor in breast cancer.
Proteinuria
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
Pruritus
Decreased plasma kallikrein 5 concentrations in patients with chronic spontaneous urticaria.
Pruritus
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
Pruritus
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
Pruritus
Patterns among Patients with Chronic Pruritus: A Retrospective Analysis of 170 Patients.
Pseudomonas Infections
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins.
Pseudomonas Infections
Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation.
Pseudomyxoma Peritonei
Pseudomyxoma peritonei: failure of activated trypsin to modify the course of the disease.
Pseudorabies
Demonstration of Aujeszky's disease virus antigen in trypsin-digested paraffin-embedded tissue sections by immunofluorescence.
Pseudorabies
Differentiation of vaccine strains and field isolates of pseudorabies (Aujeszky's disease) virus: trypsin sensitivity and mouse virulence markers.
Pseudorabies
Trypsin increases pseudorabies virus production through activation of the ERK signalling pathway.
Pseudorabies
[Use of temperature, trypsin and biological tests for the intraspecies differentiation of local strains of Aujeszky's disease virus]
Pseudoxanthoma Elasticum
Effect of selective enzymatic digestions on skin biopsies from pseudoxanthoma elasticum: an ultrastructural study.
Psoriasis
Adenosine deaminase activity, trypsin inhibitory capacity and total antioxidant capacity in psoriasis.
Psoriasis
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Psoriasis
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
Psoriasis
Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
Pulmonary Alveolar Proteinosis
Bronchoalveolar lavage with trypsin in pulmonary alveolar proteinosis.
Pulmonary Alveolar Proteinosis
Pulmonary alveolar proteinosis. Remission after therapy with trypsin and chymotrypsin.
Pulmonary Alveolar Proteinosis
Pulmonary alveolar proteinosis: successful treatment with aerosolized trypsin.
Pulmonary Alveolar Proteinosis
Trypsin aerosol treatment of pulmonary alveolar proteinosis. Case report.
Pulmonary Atelectasis
Atelectasis; physiopathology and treatment; special reference to its occurrence in bulbar poliomyelitis, and to a suggested therapeutic aid by the intrabronchial administration of trypsin.
Pulmonary Atelectasis
The use of trypsin or streptokinase-streptodornase for the therapy and prevention of atelectasis.
Pulmonary Disease, Chronic Obstructive
Decrease in the alpha 1-proteinase inhibitor Spi3 in equine bronchoalveolar lavage fluid.
Pulmonary Disease, Chronic Obstructive
Interactions of neutrophil elastase, serum trypsin inhibitory activity, and smoking history as risk factors for chronic obstructive pulmonary disease in patients with MM, MZ, and ZZ phenotypes for alpha-antitrypsin.
Pulmonary Disease, Chronic Obstructive
Interactions of neutrophil elastase, serum trypsin inhibitory activity, and smoking history as risk factors for chronic obstructive pulmonary disease in patients with MM, MZ, and ZZ phenotypes for alpha1-antitrypsin.
Pulmonary Disease, Chronic Obstructive
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Pulmonary Disease, Chronic Obstructive
Tumor-associated trypsin inhibitor (TATI) in the diagnosis of lung cancer.
Pulmonary Disease, Chronic Obstructive
[Correlations between chymase activity ,levels of tryptase, and eotaxin in the sputum of patients with chronic obstructive puhnonary disease and their clinical implications]
Pulmonary Edema
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-? and Related Pathways.
Pulmonary Embolism
[Case of postoperative recurring pulmonary embolism cured with intramuscular trypsin associated with anticoagulant therapy.]
Pulmonary Emphysema
Chronic obstructive pulmonary disease and alpha-1-antitrypsin (Pi) variation: a family study.
Pulmonary Emphysema
[Trypsin plus chymotrypsin in chronic bronchitic forms with pulmonary emphysema.]
Pulmonary Fibrosis
Imrecoxib Inhibits Paraquat-Induced Pulmonary Fibrosis through the NF-?B/Snail Signaling Pathway.
Pulmonary Fibrosis
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis.
Pulmonary Fibrosis
[Biological effect of (60)Cogamma ray on alveolar type II cells and interstitial cells of alveoliar septum in radiation pulmonary injury.]
Pulpitis
The effect of a proteolytic enzyem mixture (Orenzyme-Forte) on experimentally induced pulpitis.
Purpura
[PROTEOLYTIC PROCESSES AND PURPURA INDUCED IN HYPERTENSIVE PATIENTS. EXPERIMENTAL STUDY. I. INFLUENCE OF TRYPSIN ON HEMORRHAGIC MANIFESTATIONS OF THE TOURNIQUET TEST IN HYPERTENSIVE PATIENTS.]
Purpura
[PURPURA PROVOKED BY HYPERTHYROIDISM AND INFLUENCE ON THIS BY TRYPSIN AND A PROTEOLYTIC INHIBITOR.]
Pyelonephritis
[Activity of proteolytic enzymes and trypsin inhibitor in blood serum and kidney in pyelonephritis]
Pyelonephritis
[Kallikrein, nonspecific proteases and trypsin inhibitor in the urine of patients with pyelonephritis]
Rabies
Immunofluorescent staining of rabies virus antigen in formalin-fixed tissue after treatment with trypsin.
Rabies
Immunofluorescent staining of trypsinized formalin-fixed brain smears for rabies antigen: results compared with those obtained by standard methods for 221 suspect animal cases in Nigeria.
Rabies
Immunological studies of a 21 kDa cellular component efficiently incorporated into rabies virion grown in a BHK-21 cell culture.
Rabies
Increased immunofluorescent staining of rabies-infected, formalin-fixed brain tissue after pepsin and trypsin digestion.
Rabies
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Rabies
[Effect of trypsin and RNase on the morphology and biological properties of the rabies virus]
Rectal Neoplasms
Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Rectal Neoplasms
Evaluation of shell vial cell culture technique for the detection of bovine coronavirus.
Rectal Neoplasms
[A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension]
Relative Energy Deficiency in Sport
Technique for revealing the three-dimensional architecture of whole preserved spiculated invertebrates.
Renal Insufficiency
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Renal Insufficiency
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
Renal Insufficiency
Plasma pancreatic trypsinogens in chronic renal failure and after nephrectomy.
Renal Insufficiency
Purification and amino acid analysis of plasma acid stable trypsin inhibitor.
Renal Insufficiency
RENAL INSUFFICIENCY FOLLOWING TRYPSIN INJECTION INTO THE RENAL ARTERIES.
Renal Insufficiency
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
Renal Insufficiency
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Renal Insufficiency
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Renal Insufficiency, Chronic
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Reperfusion Injury
Attenuation of graft ischemia-reperfusion injury by urinary trypsin inhibitor in mouse intestinal transplantation.
Reperfusion Injury
Autodigestion by migrated trypsin is a major factor in small intestinal ischemia-reperfusion injury.
Reperfusion Injury
Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy.
Reperfusion Injury
Effects of ulinastatin, a urinary trypsin inhibitor, on synaptic plasticity and spatial memory in a rat model of cerebral ischemia/reperfusion injury.
Reperfusion Injury
Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
Reperfusion Injury
Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats.
Reperfusion Injury
The Protective Effects of Trypsin Inhibitor on Hepatic Ischemia-Reperfusion Injury and Liver Graft Survival.
Reperfusion Injury
Ulinastatin attenuates reperfusion injury in the isolated blood-perfused rabbit heart.
Reperfusion Injury
Urinary Trypsin Inhibition: Cardioprotection via the Reperfusion Injury Salvage Kinase Pathway.
Reperfusion Injury
Urinary trypsin inhibitor ameliorates renal tissue oxygenation after ischemic reperfusion in rats.
Reperfusion Injury
Urinary trypsin inhibitor attenuates hepatic ischemia-reperfusion injury by reducing nuclear factor-kappa B activation.
Respiratory Distress Syndrome
Evidence for pancreas injury in adult respiratory distress syndrome.
Respiratory Distress Syndrome
High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants.
Respiratory Distress Syndrome
Immunoreactive trypsin in the adult respiratory distress syndrome.
Respiratory Distress Syndrome
Intra-alveolar urinary trypsin inhibitor cannot inhibit polymorphonuclear elastase activity in the lung in postsurgical patients with acute respiratory distress syndrome.
Respiratory Distress Syndrome
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Respiratory Distress Syndrome
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Respiratory Distress Syndrome
Serum trypsin inhibitory capacity and the idiopathic respiratory distress syndrome.
Respiratory Distress Syndrome
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Respiratory Distress Syndrome
Umbilical cord serum trypsin inhibitor capacity and the idiopathic respiratory distress syndrome.
Respiratory Distress Syndrome
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
Respiratory Tract Infections
Buccal and intramuscular trypsin in respiratory tract infection.
Retinal Perforations
[Experimental study on the retinal tear. 6. Observation on retinal vessels around the retinal tear by trypsin digestion method]
Retinitis
Role of HIV and CMV in the pathogenesis of retinitis and retinal vasculopathy in AIDS patients.
Retinoblastoma
Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization.
Reye Syndrome
Serial alterations in the forms of immunoreactive pancreatic cationic trypsin in plasma from patients with acute pancreatitis.
Rhabdomyosarcoma
Cell survival and growth delay in rat R-1 tumours after radiation and vinblastine treatment.
Rheumatic Diseases
Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases.
Rheumatic Diseases
[Comparative epidemiological study in patients with rheumatic diseases illustrated in a example of a treatment with non-steroidal anti- inflammatory drugs versus an oral enzyme combination preparation]
Rheumatic Fever
Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; variations in the blood concentration of total plasmin and of trypsin inhibitor in streptococcal diseases with special reference to rheumatic fever.
Rhinitis
Protease-activated receptor 2 expression in trigeminal neurons innervating the rat nasal mucosa.
Rocky Mountain Spotted Fever
Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence.
Rotavirus Infections
Effects of antibodies, trypsin, and trypsin inhibitors on susceptibility of neonates to rotavirus infection.
Rotavirus Infections
Influence of soybean trypsin inhibitor on small bowel enzyme activities during rotavirus infection in malnourished infant mice.
Rotavirus Infections
Lipid composition and amino acid uptake during rotavirus infection and protection with trypsin inhibitor in malnourished infant mice.
Rotavirus Infections
Peroral immunization of microencapsulated human VP8 in combination with cholera toxin induces intestinal antibody responses.
Rotavirus Infections
Protection against neonatal rotavirus infection by breast milk antibodies and trypsin inhibitors.
Rotavirus Infections
Protective efficacy of trypsin inhibitor on the the gut following rotavirus infection in malnourished infant mice.
Rotavirus Infections
Rotavirus infection in newborn calves. I. Evaluation trials of certain enzymes in faeces.
Rotavirus Infections
Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice.
Rotavirus Infections
The isolation, propagation and characterization of tissue-cultured equine rotaviruses.
Rubella
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Rubella
[The hemagglutination inhibition reaction in the diagnosis of rubella. Apropos of the critical and comparative study of 252 serums treated by heparin-MnCl2 and allowed to react with trypsin treated human O erytrocytes]
Sarcoma
Antithrombin improves the maternal and neonatal outcomes but not the angiogenic factors in extremely growth-restricted fetuses at <28 weeks of gestation.
Sarcoma
Antitumor activity of Moringa oleifera (drumstick tree) flower trypsin inhibitor (MoFTI) in sarcoma 180-bearing mice.
Sarcoma
Cell surface retention sequence binding protein-1 interacts with the v-sis gene product and platelet-derived growth factor beta-type receptor in simian sarcoma virus-transformed cells.
Sarcoma
Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.
Sarcoma
Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression.
Sarcoma
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
Sarcoma
Surface proteins of fibroblast and sarcoma cells--their shedding and trypsin susceptibility.
Sarcoma
Use of trypsin for rapid and efficient purification of murine sarcoma and leukemia virus.
Sarcoma
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
Sarcoma
[Antineoplastic effects of carnosine and beta-alanine--physiological considerations of its antineoplastic effects]
Sarcoma 180
Proteolytic activities of mouse sarcoma 180 cells that are inhibited by Bowman-Birk and Kunitz protease inhibitors.
Sarcoma, Avian
Activation of ornithine decarboxylase in monolayer cells treated with trypsin.
Sarcoma, Avian
Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteins.
Scrapie
Enhancement of immunohistochemical staining of scrapie proteins and immune cells within lymph nodes of early scrapie-infected sheep.
Scrapie
Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells.
Seizures
Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis.
Seizures
Relationship between nicotine-induced seizures and hippocampal nicotinic receptors.
Seizures
The biochemical and behavioral effects of phospholipase A2 and morphine microinjections in the periaqueductal gray of the rat.
Sepsis
Effect of ulinastatin combined with thymosin alpha1 on sepsis: A systematic review and meta-analysis of Chinese and Indian patients.
Sepsis
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Sepsis
Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study.
Sepsis
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
Sepsis
The activation of neutrophil elastase-mediated fibrinolysis is not sufficient to overcome the fibrinolytic shutdown of disseminated intravascular coagulation associated with systemic inflammation.
Sepsis
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-? and Related Pathways.
Sepsis
Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model.
Sepsis
[Effect on hemostasis and thrombogenesis by septic processes especially in childhood]
Severe Acute Respiratory Syndrome
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Severe Acute Respiratory Syndrome
Entry from the cell surface of severe acute respiratory syndrome coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.
Severe Acute Respiratory Syndrome
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: implications for vaccination and antibody therapeutics.
Severe Acute Respiratory Syndrome
Protease-mediated entry via the endosome of human coronavirus 229E.
Severe Acute Respiratory Syndrome
The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19.
Sexually Transmitted Diseases
Secretion of miraculin through the function of a signal peptide conserved in the Kunitz-type soybean trypsin inhibitor family.
Shock, Cardiogenic
Effect of hemorrhagic and nortriptyline-induced shock on the porcine pancreas as evaluated by changes in serum cationic trypsin-like immunoreactivity.
Shock, Septic
Effect of intravenous and intraduodenal administration of Escherichia coli endotoxin on the porcine pancreas as evaluated by changes in the serum cationic trypsin-like immunoreactivity.
Shock, Septic
Exocrine pancreatic function in critically ill patients: septic shock versus non-septic patients.
Shock, Septic
Further evidence of bradykinin involvement in septic shock: reduction of kinin production in vivo and improved survival in rats by use of polymer tailored SBTI with longer t1/2.
Shock, Septic
Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo.
Shock, Septic
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
Shock, Septic
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
Short Bowel Syndrome
Inhibition of postprandial pancreatic and biliary secretion by loperamide in patients with short bowel syndrome.
Sinusitis
Differences in physicochemical properties between tissue plasminogen activators from human paranasal mucous membrane and pig heart.
Skin Diseases
Avidin-biotin-peroxidase complex immunohistochemistry to detect immunoglobulin in formalin fixed skin biopsies in canine autoimmune skin disease.
Skin Diseases
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Skin Diseases
Failure of intramuscular trypsin to alter the course of certain inflammatory dermatoses.
Skin Diseases
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases.
Skin Diseases
[EXPERIMENTAL AND CLINICAL STUDIES ON THE EFFECTIVENESS OF KALLIKREIN- TRYPSIN INHIBITOR (TRASYLOL) IN DERMATOSES.]
Sleep Apnea, Obstructive
[The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome]
Small Cell Lung Carcinoma
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Spinal Cord Injuries
Spinal cord transection: a quantitative analysis of elements of the connective tissue matrix formed within the site of lesion following administration of piromen, cytoxan or trypsin.
Spotted Fever Group Rickettsiosis
Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence.
Squamous Cell Carcinoma of Head and Neck
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Squamous Cell Carcinoma of Head and Neck
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Squamous Cell Carcinoma of Head and Neck
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Squamous Cell Carcinoma of Head and Neck
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Staphylococcal Infections
[Effect of trypsin on suppressor cell formation and function in localized staphylococcal infection]
Staphylococcal Infections
[Effect of trypsin on the immune response in localized staphylococcal infection]
Starvation
A trypsin inhibitor trans-4-guanidinomethylcyclohexanecarboxylic acid 4-tert-butylphenyl ester suppresses the onset of DNA synthesis in Escherichia coli cells synchronized by phosphate starvation.
Starvation
Digestive enzyme profiles reveal digestive capacity and potential energy sources in fed and starved spiny lobster (Jasus edwardsii) phyllosoma larvae.
Starvation
Effect of starvation and refeeding on digestive enzyme activities in juvenile roach, Rutilus rutilus caspicus.
Starvation
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Starvation
Influence of molting and starvation on the synthesis of proteolytic enzymes in the midgut gland of the white shrimp Penaeus vannamei.
Starvation
Ontogenetic development of digestive enzymes and effect of starvation in miiuy croaker Miichthys miiuy larvae.
Starvation
Seasonal variation in trypsin activity in juvenile Atlantic salmon upper and lower modal groups.
Starvation
Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.
Starvation
Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata.
Starvation
Surface exposure of glycosaminoglycans in resting, growing and virus transformed 3T3 cells.
Starvation
The effect of feeding on the secretion of pepsin, trypsin and chymotrypsin in the Atlantic salmon,Salmo salar L.
Starvation
The effects of starvation on digestive tract function and structure in juvenile southern catfish (Silurus meridionalis Chen).
Starvation
[Effects of starvation and re-feeding on survival rate, growth and digestive enzyme activities of juvenile Sepia pharaonis.]
Starvation
[Oxidative phosphorylation and the activity of the polyenzyme systems of rat liver mitochondrial membranes in starvation]
Steatorrhea
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Steatorrhea
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Steatorrhea
Comparative diagnostic accuracy of four tubeless pancreatic function tests in chronic pancreatitis.
Steatorrhea
Comparison of ochratoxin, aflatoxin, and T-2 toxin for their effects on selected parameters related to digestion and evidence for specific metabolism of carotenoids in chickens.
Steatorrhea
Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis.
Steatorrhea
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Steatorrhea
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Steatorrhea
Plasma immunoreactive pancreatic cationic trypsinogen in cystic fibrosis: a sensitive indicator of exocrine pancreatic dysfunction.
Steatorrhea
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
Steatorrhea
[Echostructure of the pancreas. Comparison with exocrine secretory activity of the pancreas in patients with diabetes mellitus]
Steatorrhea
[Evaluation of exocrine pancreatic function by the haptocorrin degradation test of the duodenal fluid collected by endoscopy]
steroid 21-monooxygenase deficiency
[Screening for hereditary diseases. What other screening?]
Stomach Diseases
Tumor-associated trypsin inhibitor (TATI) in benign and malignant gastric disease.
Stomach Diseases
[On the treatment of pre- and postoperative pancreatic insufficiency with trypsin inhibitors in patients with gallbladder and stomach diseases.]
Stomach Neoplasms
Analysis of Cysteine Glutathionylation in Hemoglobin of Gastric Cancer Patients using Nanoflow Liquid Chromatography Triple-Stage Mass Spectrometry.
Stomach Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Stomach Neoplasms
Comparison of the prognostic value of a panel of tissue tumor markers and established clinicopathological factors in patients with gastric cancer.
Stomach Neoplasms
Effects of endoscopic submucosal dissection on post-operative early treatment effectiveness and serum TAT-2 and GP73 expression levels in patients with early gastric cancer.
Stomach Neoplasms
Effects of super-extended paraaortic lymphadenectomy (PAL) on biological responses in totally gastrectomized patients with T3 or T4 gastric cancer.
Stomach Neoplasms
Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.
Stomach Neoplasms
Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.
Stomach Neoplasms
High tissue expression of tumour-associated trypsin inhibitor (TATI) associates with a more favourable prognosis in gastric cancer.
Stomach Neoplasms
Marked increase of trypsin(ogen) in serum of linitis plastica (gastric cancer, borrmann 4) patients.
Stomach Neoplasms
Measurement of urinary trypsin inhibitor in urine, plasma and cancer tissues of patients with stomach cancer.
Stomach Neoplasms
Production of trypsins by human gastric cancer cells correlates with their malignant phenotype.
Stomach Neoplasms
Prophylactic administration of urinary trypsin inhibitor prevents postoperative hyperamylasemia after R2 gastrectomy in patients with gastric cancer. A prospective randomized trial.
Stomach Neoplasms
Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells.
Stomach Neoplasms
Significance of the measurement of serum trypsin in patients surgically treated for gastric cancer.
Stomach Neoplasms
Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
Stomach Neoplasms
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Stomach Neoplasms
The relationship between serum tumor-associated trypsin inhibitor levels and clinicopathological parameters in patients with gastric cancer.
Stomach Neoplasms
Trypsinogen expression and early detection for peritoneal dissemination in gastric cancer.
Stomach Neoplasms
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
Stomach Neoplasms
Tumor-associated trypsin inhibitor (TATI) in benign and malignant gastric disease.
Stomach Neoplasms
[5-FU concentration in the tissue of gastric cancer, and evaluation of cancer chemotherapy with angiotensin-II]
Stomach Neoplasms
[Study of plasminogen activator and trypsin inhibitor in gastric cancer, ulcer and experimental tumor.]
Subarachnoid Hemorrhage
Protective effects of urinary trypsin inhibitor on vascular permeability following subarachnoid hemorrhage in a rat model.
Synovitis
Rheumatoid-like synovitis in rabbits by intra-articular administration of alpha 2-macroglobulin . trypsin complexes and alkylamine-treated alpha 2-macroglobulin.
Synovitis
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue.
Teratocarcinoma
Biochemical properties of the high-molecular-weight glycopeptides released from the cell surface of human teratocarcinoma cells.
Teratocarcinoma
Teratocarcinoma cell adhesion: identification of a cell-surface protein involved in calcium-dependent cell aggregation.
Testicular Neoplasms
Cytogenetic evidence for premeiotic transformation of human testicular cancers.
Tetanus
Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin.
Tetanus
Enzymatic hydrolysis of tetanus toxin by intrinsic and extrinsic proteases. Characterization of the fragments by monoclonal antibodies.
Tetanus
THE INFLUENCE OF TESTICLE EXTRACT ON THE INTRADERMAL SPREAD OF INJECTED FLUIDS AND PARTICLES.
Tetanus
[Application of theories on extraction of endocellular tetanus toxin. II. Effect of trypsin.]
Thrombasthenia
Platelet shape change: induction by trypsin and release of an acidic macroglycopeptide from washed human platelets and from those of three cases of Glanzmann's thrombasthenia.
Thromboembolism
Parenteral trypsin therapy for thrombophlebitis, thromboembolism, and chronic venous occlusion of the lower extremities: results in thirty-two cases at Brooke Army Hospital.
Thromboembolism
[Experimental research on the problem of serum protein changes caused by trypsin in the field of thromboembolism therapy.]
Thrombophilia
The risk of a first and a recurrent venous thrombosis associated with an elevated D-dimer level and an elevated thrombin potential: results of the THE-VTE study.
Thrombophlebitis
A clinical evaluation of intramuscular trypsin in the treatment of acute thrombophlebitis.
Thrombophlebitis
Clinical evaluation of trypsin in treatment of thrombophlebitis and sequelae, and hematomas after surgery of veins.
Thrombophlebitis
Parenteral trypsin therapy for thrombophlebitis, thromboembolism, and chronic venous occlusion of the lower extremities: results in thirty-two cases at Brooke Army Hospital.
Thrombophlebitis
The therapeutic effectiveness of trypsin in the treatment of thrombophlebitis.
Thrombophlebitis
[Intramuscular administration of combined trypsin and chymotrypsin in therapy of thrombophlebitis of obstetric and gynecological origin.]
Thrombophlebitis
[Therapeutic possibilities of trypsin. I. Effects of intramuscular trypsin in thrombophlebitis and phlebothrombosis; clinical research.]
Thrombophlebitis
[Treatment of wounds, thrombophlebitis and lymphostasis by trypsin electrophoresis]
Thrombosis
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis.
Thrombosis
A novel fibrin(ogen)olytic trypsin-like protease from Chinese oak silkworm (Antheraea pernyi): purification and characterization.
Thrombosis
Aptamer-peptide conjugates as a new strategy to modulate human ?-thrombin binding affinity.
Thrombosis
Characterisation of a novel series of aprotinin-derived anticoagulants. II. Comparative antithrombotic effects on primary thrombus formation in vivo.
Thrombosis
Degradation and liquefaction effect of streptokinase-Streptodornase and stabilized trypsin on necroses, crusts of fibrinoid, purulent exudate and clotted blood from leg ulcers.
Thrombosis
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors.
Thrombosis
Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors.
Thrombosis
L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor.
Thrombosis
Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics.
Thrombosis
Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow.
Thrombosis
Post-operative thrombosis of the aorta following coarctectomy; report of a case treated with intravenous trypsin.
Thrombosis
Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors.
Thrombosis
Protease-activated receptor 4: a critical participator in inflammatory response.
Thrombosis
Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury.
Thrombosis
Retrograde trypsin instillation into the renal pelvis for the dissolution of obstructive blood clots.
Thrombosis
The risk of a first and a recurrent venous thrombosis associated with an elevated D-dimer level and an elevated thrombin potential: results of the THE-VTE study.
Thrombosis
Thrombosis (infarction) induced by kappa-carrageenin in rat tail: inhibition during adjuvant arthritis.
Thrombosis
[Histological studies of occlusion of retinal veins. I. Pathogenesis of venous thrombosis as revealed by trypsin digestion method]
Thymoma
Structural similarities between the mammalian beta-adrenergic and reovirus type 3 receptors.
Thymoma
Vascular architecture as a diagnostic marker for differentiation of World Health Organization thymoma subtypes and thymic carcinoma.
Thyroid Neoplasms
Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging.
Thyrotoxicosis
[Study of peptide composition in serum albumin in patients with thyroid gland dysfunction]
Tick Infestations
Protective immunity against tick infestation in cattle vaccinated with recombinant trypsin inhibitor of Rhipicephalus microplus.
Tongue Neoplasms
Sporamin induce apoptosis in human tongue carcinoma cells by down-regulating Akt/GSK-3 signaling.
Toxemia
[Effect of pancreatic kallikrein and trypsin inhibitors on the course of postischemic toxemia]
triacylglycerol lipase deficiency
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Trichinellosis
Screening and characterization of early diagnostic antigens in excretory-secretory proteins from Trichinella spiralis intestinal infective larvae by immunoproteomics.
trypsin deficiency
Th-17 cells infiltrate the liver in human biliary atresia and are related to surgical outcome.
trypsin deficiency
[External respiratory function in patients with primary pulmonary emphysema etiologically related to alpha 1-antitrypsin deficiency]
trypsin deficiency
[Malabsorption and developmental retardation due to secondary trypsin deficiency]
trypsin deficiency
[Recurrent pneumothorax: its association with alpha-1 trypsin deficiency.]
trypsin deficiency
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
Tuberculosis
Antigenic epitopes on Mycobacterium tuberculosis recognized by antibodies in tuberculosis and mouse antisera.
Tuberculosis
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Tuberculosis
Effect of trypsin and ribonuclease on the immunogenic activity of ribosomes and ribonucleic acid isolated from Mycobacterium tuberculosis.
Tuberculosis
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
Tuberculosis
Isolation of tuberculin peptides from tuberculin purified protein derivative (PPD).
Tuberculosis
Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis.
Tuberculosis
[Effects of trypsin and the products of trypsinization of the liver, lung and spleen on the sensitivity of Mycobacterium tuberculosis to chemotherapeutic substances]
Tuberculosis, Lymph Node
The use of trypsin in the therapy of tuberculous lymphadenitis and tuberculous fistulae.
Tuberculosis, Meningeal
A case report of miliary tuberculosis and tuberculous meningitis treated with trypsin and antibiotics: one year follow-up.
Tuberculosis, Miliary
A case report of miliary tuberculosis and tuberculous meningitis treated with trypsin and antibiotics: one year follow-up.
Tuberculosis, Pleural
[The clinical value of determining the general antitrypsin activity of the blood and exudate in tuberculous pleurisy]
Tuberculosis, Pulmonary
[Clinical study of a group of pulmonary tuberculosis patients treated with trypsin aerosol; preventive note.]
Tuberculosis, Pulmonary
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
Tuberculosis, Pulmonary
[On the parenteral use of trypsin in therapy of pulmonary tuberculosis.]
Tumor Virus Infections
Further studies on surface antigen of Shope papilloma cells: trypsin sensitivity.
Tumor Virus Infections
INDUCTION OF TUMORS IN DOMESTIC RABBITS WITH NUCLEIC ACID PREPARATIONS FROM PARTIALLY PURIFIED SHOPE PAPILLOMA VIRUS AND FROM EXTRACTS OF THE PAPILLOMAS OF DOMESTIC AND COTTONTAIL RABBITS.
Typhoid Fever
[Use of skim milk treated with peptin and trypsin as a culture medium for typhoid and paratyphoid B bacteria; a contribution on the use of the Wilson-Blair medium.]
Typhus, Epidemic Louse-Borne
Partial purification and characterization of the major species-specific protein antigens of Rickettsia typhi and Rickettsia prowazekii identified by rocket immunoelectrophoresis.
Upper Extremity Deep Vein Thrombosis
[Trypsin electrophoresis in the treatment of Paget-Schroetter syndrome]
Ureteral Obstruction
Ulinastatin attenuates renal interstitial inflammation and inhibits fibrosis progression in rats under unilateral ureteral obstruction.
Ureteral Obstruction
Ulinastatin inhibits unilateral ureteral obstruction-induced renal interstitial fibrosis in rats via transforming growth factor ? (TGF-?)/Smad signalling pathways.
Urinary Bladder Diseases
[Experimental investigations on trypsin treatment of bladder diseases.]
Urinary Bladder Neoplasms
Angiotensin-II combined intra-arterial chemotherapy for locally advanced bladder cancer: a case series study at a single institution.
Urinary Bladder Neoplasms
Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
Urinary Bladder Neoplasms
Evaluation of urine tumor-associated trypsin inhibitor, CYFRA 21-1, and urinary bladder cancer antigen for detection of high-grade bladder carcinoma.
Urinary Bladder Neoplasms
Optimizing Orthotopic Bladder Tumor Implantation in a Syngeneic Mouse Model.
Urinary Bladder Neoplasms
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Urinary Bladder Neoplasms
Prognostic value of the combined expression of tumor-associated trypsin inhibitor (TATI) and p53 in patients with bladder cancer undergoing radical cystectomy.
Urinary Bladder Neoplasms
Specific sequences of fibronectin activate the protein kinase C signal transduction pathway in invasive bladder cancer.
Urinary Bladder Neoplasms
The antitumor effect of the novel cancer-specific adenovirus Ad-VEGFR on bladder cancer in vitro and in vivo.
Urinary Bladder Neoplasms
Tumor-associated trypsin inhibitor as a prognostic factor during follow-up of bladder cancer.
Urinary Tract Infections
The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method.
Urinary Tract Infections
Urinary trypsin levels observed in pancreas transplant patients with duodenocystostomies promote in vitro fibrinolysis and in vivo bacterial adherence to urothelial surfaces.
Urinary Tract Infections
[The treatment of urinary tract infection following transurethral prostatic resection by use of trypure solution.]
Uterine Cervical Neoplasms
Alpha 1-antitrypsin: a possible tool for diagnosis of cervical cancer.
Uterine Cervical Neoplasms
Characterization of the anti-cancer-cell parasporal proteins of a Bacillus thuringiensis isolate.
Uterine Cervical Neoplasms
Effects of the Medicago scutellata trypsin inhibitor (MsTI) on cisplatin-induced cytotoxicity in human breast and cervical cancer cells.
Uterine Cervical Neoplasms
Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation.
Uterine Cervical Neoplasms
Purification and identification of novel cytotoxic oligopeptides from soft coral Sarcophyton glaucum.
Uterine Cervical Neoplasms
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Uterine Cervical Neoplasms
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
Uterine Cervical Neoplasms
[Primary effect of preoperative intra-arterial infusion chemotherapy in cervical cancer]
Uterine Cervical Neoplasms
[Radioimmunologic determination of gastrin, insulin, C-peptide, glucagon and trypsin in the combined radiotherapy of cervix cancer]
Vaccinia
Functional domains of vaccinia virus mRNA capping enzyme. Analysis by limited tryptic digestion.
Vaccinia
Mechanism of inhibition of vaccinia DNA topoisomerase by novobiocin and coumermycin.
Vaccinia
Modification of vaccinia virus penetration proteins analyzed by monoclonal antibodies.
Vaccinia
Phosphorylation in vivo of a vaccinia-virus structural protein found associated with the ribosomes from infected cells.
Vaccinia
[Effects of intramuscular trypsin on the course of experimental infection by vaccinia virus in rabbits.]
Vascular System Injuries
Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase.
Vascular System Injuries
Roscovitine attenuates intimal hyperplasia via inhibiting NF-?B and STAT3 activation induced by TNF-? in vascular smooth muscle cells.
Vasculitis
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor.
Venous Thrombosis
Treatment of phlebothrombosis and its sequelae with intra-arterial trypsin.
Venous Thrombosis
Trypsin and thrombin induced venous thrombosis and its prevention with dicumarol, 3,3' methylenebis (4 hydroxycoumarin).
Venous Thrombosis
[Histological studies of occlusion of retinal veins. I. Pathogenesis of venous thrombosis as revealed by trypsin digestion method]
Venous Thrombosis
[Therapeutic possibilities of trypsin. I. Effects of intramuscular trypsin in thrombophlebitis and phlebothrombosis; clinical research.]
Ventricular Premature Complexes
Relationship between hypertensive left ventricular hypertrophy, neurohormonal factors and ventricular arrhythmias in very old patients.
Ventricular Premature Complexes
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias]
Vesicular Stomatitis
Enhanced growth and plaquing of rabies virus in static chick embryo cell culture.
Vesicular Stomatitis
Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.
Vesicular Stomatitis
Production of interferon by bovine peripheral blood monocytes infected with bovid herpesvirus 2.
Vesicular Stomatitis
The structure of vesicular stomatitis virus membrane. A phosphorus nuclear magnetic resonance approach.
Vesicular Stomatitis
Trypsin treatment of bovine ova after in vitro exposure to vesicular stomatitis virus.
Vesicular Stomatitis
[Hemagglutinating activity of various viruses on trypsinized erythrocytes]
Virus Diseases
Detection of viral infection by immunofluorescence in formalin-fixed tissues, pretreated with trypsin.
Virus Diseases
Development of a rapid and sensitive quantitative assay for rotavirus based on flow cytometry.
Virus Diseases
Development of mouse monoclonal antibody for detecting hemagglutinin of avian influenza A(H7N9) virus and preventing virus infection.
Virus Diseases
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Virus Diseases
Effect of mosquito midgut trypsin activity on dengue-2 virus infection and dissemination in Aedes aegypti.
Virus Diseases
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Virus Diseases
Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection.
Virus Diseases
Inactivation of HIV-1 by trypsin and its use in demonstrating specific virus infection of cells.
Virus Diseases
Infection enhancement of influenza A NWS virus in primary murine macrophages by anti-hemagglutinin monoclonal antibody.
Virus Diseases
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Virus Diseases
Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.
Virus Diseases
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Virus Diseases
Proteins induced in tissue culture by four isolates of Theiler's murine encephalomyelitis virus.
Virus Diseases
Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion.
Virus Diseases
Role of trypsin in the replication of Avian metapneumovirus subtype C (strain MN-2a) and its entry into the Vero cells.
Virus Diseases
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Virus Diseases
Study of cell surface antigens induced by herpes simplex virus. Note II. Some properties of the antigens.
Virus Diseases
The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation.
Virus Diseases
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Virus Diseases
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Vitamin E Deficiency
[The effect of vitamin E deficiency on enzyme activity and the status of the membrane fraction of rat liver microsomes]
Vitiligo
A randomized pilot study to compare hair follicle cell suspensions prepared using trypsin alone versus trypsin in combination with collagenase type-I for transplantation in vitiligo.
Waldenstrom Macroglobulinemia
Primary structure of human J chain: isolation and characterization of tryptic and chymotryptic peptides of human J chain.
Wheat Hypersensitivity
Reduction of Allergenic Potential in Bread Wheat RNAi Transgenic Lines Silenced for CM3, CM16 and 0.28ATI Genes.
Whooping Cough
Activation of human colon mast cells through proteinase activated receptor-2.
Whooping Cough
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.
Whooping Cough
Cooperative phenomena in binding and activation of Bordetella pertussis adenylate cyclase by calmodulin.
Whooping Cough
Dissociation of catalytic and invasive activities of Bordetella pertussis adenylate cyclase.
Whooping Cough
Effect of pertussis toxin and herbimycin A on proteinase-activated receptor 2-mediated cyclooxygenase 2 expression in Helicobacter pylori-infected gastric epithelial AGS cells.
Whooping Cough
Endogenous trypsin receptors in Xenopus oocytes: linkage to internal calcium stores.
Whooping Cough
Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation.
Whooping Cough
Interaction of Bordetella pertussis adenylate cyclase with calmodulin. Identification of two separated calmodulin-binding domains.
Whooping Cough
Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis.
Whooping Cough
Potentiation of cyclic adenosine monophosphate production by thrombin in the human erythroleukemia cell line, HEL.
Whooping Cough
Protease treatment of pertussis toxin identifies the preferential cleavage of the S1 subunit.
Whooping Cough
Seminal fluid factor increases the resistance of the tight junctional complex of cultured human cervical epithelium CaSki cells.
Whooping Cough
Structural flexibility of the calmodulin-binding locus in Bordetella pertussis adenylate cyclase. Reconstitution of catalytically active species from fragments or inactive forms of the enzyme.
Whooping Cough
The effects of basic pancreatic trypsin inhibitor (BPTI) incorporated in Freund's complete adjuvant and in Freund's incomplete adjuvant containing Bordetella pertussis organisms (Per). Suppressive effect on cell mediated response to purified protein derivative and competing effect on antibody formation to Per in guinea pigs.
Whooping Cough
Treatment of human platelets with trypsin, thrombin, or collagen inhibits the pertussis toxin-induced ADP-ribosylation of a 41-kDa protein.
Whooping Cough
[Localization of segments in the Gs protein interacting with adenylate cyclase using a Gs/G0-chimera]
Wilms Tumor
Immunohistochemistry for the differentiation of peritoneal disseminated carcinoma of unknown origin.
Wound Infection
Evaluation of Mannosidase and Trypsin Enzymes Effects on Biofilm Production of Pseudomonas aeruginosa Isolated from Burn Wound Infections.
Yellow Fever
A temporal profile of the endocrine control of trypsin synthesis in the yellow fever mosquito, Aedes aegypti.
Yellow Fever
Enhanced activity of an insecticidal protein, trypsin modulating oostatic factor (TMOF), through conjugation with aliphatic polyethylene glycol.
Yellow Fever
Increase in the size of the amino acid pool is sufficient to activate translation of early trypsin mRNA in Aedes aegypti midgut.
Yellow Fever
Polyamines, and effects from reducing their synthesis during egg development in the yellow fever mosquito, Aedes aegypti.
Yellow Fever
[Direct immunofluorescence demonstration of yellow fever antigens in hepatic tissue pre-treated with trypsin]
Zellweger Syndrome
Properties of the enzymes catalyzing the biosynthesis of lysophosphatidate and its ether analog in cultured fibroblasts from Zellweger syndrome patients and normal controls.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.07744
benzoyl-DL-Arg-7-amido-4-methylcoumarin
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
0.00399
enhanced green fluorescent protein-T1
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
-
0.00421
enhanced green fluorescent protein-T1nb
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
-
0.00927
tert-butoxycarbonyl-L-Gln-L-Ala-L-Arg-7-amido-4-methylcoumarin
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
0.0135
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
0.0198
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193A, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
0.0213
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193Y, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
0.0252
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
wild type enzyme, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
0.0274
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193F, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
0.0141
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G142A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
0.0203
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
0.0266
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
0.0298
Z-Gly-Pro-Arg-p-nitroanilide
-
wild type enzyme, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
0.0788
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G19A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
0.346
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G184A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.25
benzoyl-DL-Arg-7-amido-4-methylcoumarin
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
1.33
benzoyl-DL-Arg-p-nitroanilide
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
0.26
enhanced green fluorescent protein-T1
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
-
0.85
enhanced green fluorescent protein-T1nb
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
-
1.41
tert-butoxycarbonyl-L-Gln-L-Ala-L-Arg-7-amido-4-methylcoumarin
-
in 10 mM Tris, 20 mM CaCl2, pH 7.4, at 37°C
23.5
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide
-
isozyme trypsin-1, in 50 mM Tris, pH 8.0, 100 mM NaCl, 6 mM CaCl2
32.7
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide
-
isozyme trypsin-2, in 50 mM Tris, pH 8.0, 100 mM NaCl, 6 mM CaCl2
70.5
N-benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide
-
isozyme trypsin-4, in 50 mM Tris, pH 8.0, 100 mM NaCl, 6 mM CaCl2
110
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
124
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193A, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
133
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193Y, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
158
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
wild type enzyme, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
162
N-carbobenzyloxy-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193F, in 50 mM Tricine, 10 mM CaCl2, pH 8.0 at 20°C
3.86
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G142A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
20 - 50
Z-Gly-Pro-Arg-p-nitroanilide
-
wild type enzyme, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
29.2
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G184A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
51.5
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G/G19A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
54.1
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193G, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
83.6
Z-Gly-Pro-Arg-p-nitroanilide
-
mutant enzyme R193A, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
88.2
Z-Gly-Pro-Arg-p-nitroanilide
-
wild type enzyme, in 20 mM Tricine,10 mM CaCl2, at pH 8.0 and 20°C
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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.0000188
SVIGCWTKSIPPRPCFVK-amide
-
in 10 mM phosphate buffer, pH 7.4, containing 2.7 mM KCl and 137 mM NaCl, at 37°C
0.0000542
SVIGCWTRSIPPRPCFVK-amide
-
in 10 mM phosphate buffer, pH 7.4, containing 2.7 mM KCl and 137 mM NaCl, at 37°C
additional information
additional information
-
pseudo-first-order inhibition kinetics for trypsin, overview
-
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
5 - 9
-
enhanced green fluorescent protein-T1 can be cleaved by trypsin under buffer conditions from pH 5 to pH 9
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
95436, 95453, 95454, 650209, 678332, 679743, 680807, 681538, 681733, 682760, 695428, 695451, 695520, 695996, 696032, 696328, 697021, 697400, 697406, 700007, 700478, 701195, 701375, 707409, 707900, 709306, 709845, 717901, 732138
-
-
brenda
pancreatic isoforms cationic trypsin, anionic trypsin, and mesotrypsin
-
-
brenda
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
-
isoform trypsin IV is expressed in human renal epithelial cells and can increase epithelial sodium channel-mediated sodium transport in cultured human airway epithelial cells
brenda
-
fibroblast-like synovial lining of rheumatoid arthritis synovial membrane
brenda
additional information
-
trypsinogen is expressed in various other healthy and malignant tissues
brenda
-
trypsinogen-4 is the only trypsin-isoenzyme expressed in the brain
brenda
-
trypsin is produced as a proenzyme, trypsinogen, mainly by the pancreas, and it is activated in the gastrointestinal tract by enterokinase
brenda
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
physiological function
additional information
-
a fibronectin type III-like peptide from aqueous extract of human placenta, used as a licensed drug for wound healing, tightly complexes the enzyme and regulates its activity, near-irreversible binding, modeling, overview
physiological function
-
active trypsin participates in the digestion of food by degradation of dietary proteins and by activation of other digestive enzymes in the small intestine
physiological function
-
isoforms trypsin IV and trypsin I can stimulate epithelial sodium channel heterologously expressed in Xenopus oocytes. Epithelial sodium channel cleavage and activation by trypsin IV but not by trypsin I requires a critical cleavage site, i.e. Lys189 in the extracellular domain of the gamma-subunit. Channel activation by trypsin I is prevented by mutating three putative cleavage sites (Lys168, Lys170, and Arg172) in addition to mutating previously described prostasin (RKRK178), plasmin (Lys189), and neutrophil elastase (Val182 and Val193) sites
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). TRY3_HUMAN
304
0
32529
Swiss-Prot
other Location (Reliability: 2)
TRY6_HUMAN
247
0
26537
Swiss-Prot
Secretory Pathway (Reliability: 2)
PRS58_HUMAN
241
0
27085
Swiss-Prot
Secretory Pathway (Reliability: 1)
TRY1_HUMAN
247
0
26558
Swiss-Prot
Secretory Pathway (Reliability: 2)
TRY2_HUMAN
247
0
26488
Swiss-Prot
Secretory Pathway (Reliability: 2)
Q7Z5P3_HUMAN
53
0
5728
TrEMBL
other Location (Reliability: 1)
Q7Z5Y9_HUMAN
53
0
5831
TrEMBL
other Location (Reliability: 1)
Q86W20_HUMAN
84
0
9167
TrEMBL
other Location (Reliability: 1)
A0A1B0RPQ5_HUMAN
680
0
76211
TrEMBL
Secretory Pathway (Reliability: 1)
Q53ZX8_HUMAN
84
0
9148
TrEMBL
other Location (Reliability: 1)
Q53ZX9_HUMAN
84
0
9114
TrEMBL
other Location (Reliability: 1)
Q86W17_HUMAN
84
0
9200
TrEMBL
other Location (Reliability: 1)
Q53ZV8_HUMAN
53
0
5772
TrEMBL
other Location (Reliability: 1)
Q53ZX7_HUMAN
84
0
9114
TrEMBL
other Location (Reliability: 1)
Q53ZF3_HUMAN
53
0
5800
TrEMBL
other Location (Reliability: 1)
Q86W19_HUMAN
84
0
9240
TrEMBL
other Location (Reliability: 1)
Q86W18_HUMAN
84
0
9153
TrEMBL
other Location (Reliability: 1)
Q7Z445_HUMAN
22
0
2355
TrEMBL
other Location (Reliability: 1)
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PDB
SCOP
CATH
UNIPROT
ORGANISM
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
24000
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POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
-
trypsin is produced as a proenzyme, trypsinogen, mainly by the pancreas, and it is activated in the gastrointestinal tract by enterokinase
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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
R193A
R193F
-
the mutation does not affect the activation energy of the reaction, but significantly alters the preexponential term of the Arrhenius equation
R193G
R193Y
-
the mutation does not affect the activation energy of the reaction, but significantly alters the preexponential term of the Arrhenius equation
R193A
-
the mutation does not affect the activation energy of the reaction, but significantly alters the preexponential term of the Arrhenius equation
R193G
-
the mutation does not affect the activation energy of the reaction, but significantly alters the preexponential term of the Arrhenius equation
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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
a fibronectin type III-like peptide from aqueous extract of human placenta, used as a licensed drug for wound healing, tightly complexes the enzyme and protects it against autodigestion. Trypsin retains 40% of activity at constant level between 20 and 26 days in presence of the extract against complete inactivation in its absence. The peptide-trypsin complex is dissociated in presence of high concentration of substrates
-
enzyme immobilization in the layer structure of polyelectrolyte microcapsules leads to activity reduction of up to 90%
-
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Q Sepharose Fast Flow column chromatography and Phenyl Sepharose Fast Flow column chromatography
-
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
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RENATURED/Commentary
ORGANISM
UNIPROT
LITERATURE
denatured trypsinogen is rapidly diluted with re-folding buffer (0.7 M guanidine-HCl, 0.1 M Tris-HCl, pH 8.0, containing 10 mM benzamidine, 2 mM L-cysteine, and 1 mM L-cystine)
-
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
medicine
-
use of enzyme and its regulators as markers of prognosis and disease activity in rheumatoid arthritis
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Monti, J.C.; Mermoud, A.F.; Jolles, P.
Trypsin in human milk
Experientia
42
39-41
1986
Homo sapiens
brenda
Gaboriaud, C.; Guy-Crotte, O.; Forest, E.; Fontecilla-Camps, J.C.
Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151
J. Mol. Biol.
259
995-1010
1996
Homo sapiens
brenda
Ogden, J.M.; O'Keefe, S.J.D.; Marks, I.N.
Development of a method for the purification of human trypsin by a single step affinity chromatography suitable for human isotope incorporation studies
Clin. Chim. Acta
212
141-147
1992
Homo sapiens
brenda
Mitsudo, K.; Jayakumar, A.; Henderson, Y.; Frederick, M.J.; Kang, Y.; Wang, M.; El-Naggar, A.K.; Clayman, G.L.
Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis
Biochemistry
42
3874-3881
2003
Homo sapiens
brenda
Stenman, M.; Ainola, M.; Valmu, L.; Bjartell, A.; Ma, G.; Stenman, U.H.; Sorsa, T.; Luukkainen, R.; Konttinen, Y.T.
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue
Am. J. Pathol.
167
1119-1124
2005
Bos taurus, Homo sapiens
brenda
Grishina, Z.; Ostrowska, E.; Halangk, W.; Sahin-Toth, M.; Reiser, G.
Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1
Br. J. Pharmacol.
146
990-999
2005
Homo sapiens
brenda
Gombos, L.; Kardos, J.; Patthy, A.; Medveczky, P.; Szilagyi, L.; Malnasi-Csizmadia, A.; Graf, L.
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges
Biochemistry
47
1675-1684
2008
Homo sapiens
brenda
Szepessy, E.; Sahin-Toth, M.
Human mesotrypsin exhibits restricted S1 subsite specificity with a strong preference for small polar side chains
FEBS J.
273
2942-2954
2006
Homo sapiens
brenda
Knecht, W.; Cottrell, G.S.; Amadesi, S.; Mohlin, J.; Skaregaerde, A.; Gedda, K.; Peterson, A.; Chapman, K.; Hollenberg, M.D.; Vergnolle, N.; Bunnett, N.W.
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia
J. Biol. Chem.
282
26089-26100
2007
Homo sapiens, Rattus norvegicus
brenda
Wang, Y.; Luo, W.; Wartmann, T.; Halangk, W.; Sahin-Toth, M.; Reiser, G.
Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes
J. Neurochem.
99
759-769
2006
Homo sapiens
brenda
Garbers, E.; Mitloehner, R.; Georgieva, R.; Baeumler, H.
Activity of immobilized trypsin in the layer structure of polyelectrolyte microcapsules (PEMC)
Macromol. Biosci.
7
1243-1249
2007
Homo sapiens
brenda
Toth, J.; Simon, Z.; Medveczky, P.; Gombos, L.; Jelinek, B.; Szilagyi, L.; Graf, L.; Malnasi-Csizmadia, A.
Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics
Proteins
67
1119-1127
2007
Homo sapiens
brenda
Paczek, L.; Michalska, W.; Bartlomiejczyk, I.
Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process
Age Ageing
37
318-323
2008
Homo sapiens
brenda
Elphick, D.; Liddell, S.; Mahida, Y.R.
Impaired luminal processing of human defensin-5 in Crohns disease: persistence in a complex with chymotrypsinogen and trypsin
Am. J. Pathol.
172
702-713
2008
Homo sapiens
brenda
Rungrotmongkol, T.; Decha, P.; Malaisree, M.; Sompornpisut, P.; Hannongbua, S.
Comment on "Cleavage mechanism of the H5N1 hemagglutinin by trypsin and furin" [Amino Acids 2008, January 31, Doi: 10.1007/s00726-007-0611-3]
Amino Acids
35
511-512
2008
Homo sapiens
brenda
Song, G.; Zhou, M.; Chen, W.; Chen, T.; Walker, B.; Shaw, C.
HV-BBI--a novel amphibian skin Bowman-Birk-like trypsin inhibitor
Biochem. Biophys. Res. Commun.
372
191-196
2008
Homo sapiens
brenda
Wu, Z.L.; Ethen, C.; Hickey, G.E.; Jiang, W.
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion
Biochem. Biophys. Res. Commun.
379
749-753
2009
Homo sapiens
brenda
Chen, N.; Zou, J.; Wang, S.; Ye, Y.; Huang, Y.; Gadda, G.; Yang, J.J.
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells
Biochemistry
48
3519-3526
2009
Homo sapiens
brenda
Kim, M.S.; Kim, Y.K.; Lee, D.H.; Seo, J.E.; Cho, K.H.; Eun, H.C.; Chung, J.H.
Acute exposure of human skin to ultraviolet or infrared radiation or heat stimuli increases mast cell numbers and tryptase expression in human skin in vivo
Br. J. Dermatol.
160
393-402
2009
Homo sapiens
brenda
Kashyap, R.S.; Nayak, A.R.; Deshpande, P.S.; Kabra, D.; Purohit, H.J.; Taori, G.M.; Daginawala, H.F.
Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke
Clin. Chim. Acta
402
160-163
2009
Homo sapiens
brenda
Morisawa, Y.; Kitamura, A.; Ujihara, T.; Zushi, N.; Kuzume, K.; Shimanouchi, Y.; Tamura, S.; Wakiguchi, H.; Saito, H.; Matsumoto, K.
Effect of heat treatment and enzymatic digestion on the B cell epitopes of cows milk proteins
Clin. Exp. Allergy
39
918-925
2009
Homo sapiens
brenda
McEuen, A.R.; Walls, A.F.
Purification and characterization of mast cell tryptase and chymase from human tissues
Methods Mol. Med.
138
299-317
2008
Homo sapiens
brenda
Koistinen, H.; Koistinen, R.; Zhang, W.M.; Valmu, L.; Stenman, U.H.
Nexin-1 inhibits the activity of human brain trypsin
Neuroscience
160
97-102
2009
Homo sapiens
brenda
Tsujimura, S.; Saito, K.; Nakayamada, S.; Tanaka, Y.
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases
Rheumatology
47
907-913
2008
Homo sapiens
brenda
Carr, M.N.; Torres, S.M.; Koch, S.N.; Reiter, L.V.
Investigation of the pruritogenic effects of histamine, serotonin, tryptase, substance P and interleukin-2 in healthy dogs
Vet. Dermatol.
20
105-110
2009
Homo sapiens
brenda
Fang, E.F.; Wong, J.H.; Bah, C.S.; Lin, P.; Tsao, S.W.; Ng, T.B.
Bauhinia variegata var. variegata trypsin inhibitor: from isolation to potential medicinal applications
Biochem. Biophys. Res. Commun.
396
806-811
2010
Homo sapiens
brenda
Wu, P.; Weisell, J.; Pakkala, M.; Peraekylae, M.; Zhu, L.; Koistinen, R.; Koivunen, E.; Stenman, U.H.; Naervaenen, A.; Koistinen, H.
Identification of novel peptide inhibitors for human trypsins
Biol. Chem.
391
283-293
2010
Homo sapiens
brenda
Gaber, A.; Johansson, M.; Stenman, U.H.; Hotakainen, K.; Ponten, F.; Glimelius, B.; Bjartell, A.; Jirstroem, K.; Birgisson, H.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer
Br. J. Cancer
100
1540-1548
2009
Homo sapiens
brenda
Hashemi, M.; Mehrabifar, H.; Daliri, M.; Ghavami, S.
Adenosine deaminase activity, trypsin inhibitory capacity and total antioxidant capacity in psoriasis
J. Eur. Acad. Dermatol. Venereol.
24
329-334
2010
Homo sapiens
brenda
Avanzo, P.; Sabotic, J.; Anzlovar, S.; Popovic, T.; Leonardi, A.; Pain, R.H.; Kos, J.; Brzin, J.
Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions
Microbiology
155
3971-3981
2009
Homo sapiens
brenda
De, D.; Chakraborty, P.D.; Bhattacharyya, D.
Regulation of trypsin activity by peptide fraction of an aqueous extract of human placenta used as wound healer
J. Cell. Physiol.
226
2033-2040
2010
Homo sapiens
brenda
Haerteis, S.; Krappitz, A.; Krappitz, M.; Murphy, J.; Bertog, M.; Krueger, B.; Nacken, R.; Chung, H.; Hollenberg, M.; Knecht, W.; Bunnett, N.; Korbmacher, C.
Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites
J. Biol. Chem.
289
19067-19078
2014
Homo sapiens
brenda
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