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Information on EC 3.4.11.5 - prolyl aminopeptidase and Organism(s) Homo sapiens

for references in articles please use BRENDA:EC3.4.11.5
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.5 prolyl aminopeptidase
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This record set is specific for:
Homo sapiens
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Word Map
The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
release of N-terminal proline from a peptide
Synonyms
pap, aminopeptidase p, proline iminopeptidase, prolyl aminopeptidase, proline aminopeptidase, pepip, tspap1, proline-specific aminopeptidase, tepap, l-proline aminopeptidase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
aminopeptidase, proline
-
-
-
-
cytosol aminopeptidase V
-
-
-
-
L-proline aminopeptidase
-
-
-
-
L-prolyl-peptide hydrolase
-
-
-
-
PAP
-
-
-
-
PIP
-
-
-
-
Pro-X aminopeptidase
-
-
-
-
proline aminopeptidase
-
-
-
-
Prolyl aminopeptidase
-
-
-
-
Tricorn protease interacting factor F1
-
-
-
-
additional information
-
probably identical with EC 3.4.11.1 in mammals
PATHWAY SOURCE
PATHWAYS
CAS REGISTRY NUMBER
COMMENTARY hide
9025-40-5
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
-
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
AMPL_HUMAN
519
0
56166
Swiss-Prot
Mitochondrion (Reliability: 1)
V9HW38_HUMAN
519
0
56049
TrEMBL
Mitochondrion (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
300000
-
gel filtration
550000
-
6 * 550000, SDS-PAGE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexamer
-
6 * 550000, SDS-PAGE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Matsushima, M.; Takahashi, T.; Ichinose, M.; Miki, K.; Kurokawa, K.; Takahashi, K.
Prolyl aminopeptidases from pig intestinal mucosa and human liver: Purification, characterization and possible identity with leucyl aminopeptidase
Biomed. Res.
12
323-333
1991
Homo sapiens, Sus scrofa
-
Manually annotated by BRENDA team