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Information on EC 3.2.1.52 - beta-N-acetylhexosaminidase and Organism(s) Gallus gallus

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EC Tree
IUBMB Comments
Acts on N-acetylglucosides and N-acetylgalactosides.
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This record set is specific for:
Gallus gallus
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The taxonomic range for the selected organisms is: Gallus gallus
The enzyme appears in selected viruses and cellular organisms
Synonyms
beta-hexosaminidase, hexosaminidase, n-acetyl-beta-glucosaminidase, o-glcnacase, hex a, n-acetylglucosaminidase, hexosaminidase a, beta-n-acetylhexosaminidase, hex b, beta-hexosaminidase a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase
-
-
-
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65 kDa epididymal boar protein
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-
-
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beta-acetylaminodeoxyhexosidase
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-
-
-
beta-acetylhexosaminidase
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-
-
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beta-acetylhexosaminidinase
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-
-
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beta-D-hexosaminidase
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-
-
-
beta-D-N-acetylhexosaminidase
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-
-
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Beta-GlcNAcase
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-
-
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beta-hexosaminidase
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-
-
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beta-N-acetyl-D-hexosaminidase
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-
-
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beta-N-acetyl-hexosaminidase
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-
-
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beta-N-acetylgalactosaminidase
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-
-
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beta-N-acetylglucosaminidase
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-
-
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Beta-N-acetylhexosaminidase
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-
-
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beta-NAHA
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-
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Beta-NAHASE
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-
-
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chitobiase
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-
-
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Hex
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-
-
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hexosaminidase
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-
-
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hexosaminidase A
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-
-
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N-acetyl-beta-D-hexosaminidase
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N-acetyl-beta-glucosaminidase
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-
-
-
N-acetyl-beta-hexosaminidase
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-
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N-acetylhexosaminidase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
O-glycosyl bond hydrolysis
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-
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-
SYSTEMATIC NAME
IUBMB Comments
beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase
Acts on N-acetylglucosides and N-acetylgalactosides.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-33-3
c.f. EC 3.2.1.165
9027-52-5
deleted
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide + H2O
4-methylumbelliferone + N-acetyl-beta-D-glucosamine
show the reaction diagram
-
-
-
-
?
N-acetyl-beta-D-hexosaminides + H2O
N-acetyl-D-hexosamines
show the reaction diagram
-
-
-
?
p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside + H2O
2-acetamido-2-deoxy-D-glucose + p-nitrophenol
show the reaction diagram
-
egg white, lysosomal and microsomal enzyme
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
N-acetyl-beta-D-hexosaminides + H2O
N-acetyl-D-hexosamines
show the reaction diagram
-
-
-
?
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
27
4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide
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-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
62
-
substrate: p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside, microsomal enzyme
68.4
-
substrate: p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside, egg white-enzyme
84.7
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substrate: p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside, lysosomal enzyme
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
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Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
egg white
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
F1NB63_CHICK
560
1
64529
TrEMBL
Secretory Pathway (Reliability: 2)
A0A1L1RT07_CHICK
631
0
70602
TrEMBL
Secretory Pathway (Reliability: 2)
A0A1D5P3P4_CHICK
467
0
53066
TrEMBL
other Location (Reliability: 4)
Q5ZI46_CHICK
526
0
58948
TrEMBL
Secretory Pathway (Reliability: 2)
F1NTQ2_CHICK
558
1
63008
TrEMBL
Secretory Pathway (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
53000
-
lysosomal enzyme, SDS-PAGE
68000
-
egg white-enzyme, SDS-PAGE
69000
-
gel filtration
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer
-
1 * 68000 + 1 * 53000, SDS-PAGE, microsomal enzyme
monomer
-
1 * 69000, SDS-PAGE
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
lyophilization
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
lysosomal enzyme 550fold, microsomal enzyme 756fold, egg white-enzyme 2206fold
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ogawa, Y.; Nakamura, R.; Sato, Y.
Purification of beta-N-acetylhexosaminidase from egg white abd the microsomal and lysosomal fractions of hen oviduct
Agric. Biol. Chem.
47
2085-2089
1983
Gallus gallus
-
Manually annotated by BRENDA team
Moon, J.K.; Han, B.K.; Jo, D.H.
Purification and characterization of a N-acetyl-beta-D-hexosaminidase from broiler serum
Adv. Chitin Sci.
6
271-272
2002
Gallus gallus
-
Manually annotated by BRENDA team