Reference on EC 3.1.6.13 - iduronate-2-sulfatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Di Natale, P.; Ronsisvalle, L.
Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta
Biochim. Biophys. Acta
661
106-111
1981
Homo sapiens
Yutaka, T.; Fluharty, A.L.; Stevens, R.L.; Kihara, H.
Purification and some properties of human liver iduronate sulfatase
J. Biochem.
91
433-441
1982
Homo sapiens
Wasteson, A.; Neufeld, E.F.
Iduronate sulfatase from human plasma
Methods Enzymol.
83
573-578
1982
Homo sapiens
Archer, I.M.; Harper, P.S.; Wusteman, F.S.
Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids
Biochim. Biophys. Acta
708
134-140
1982
Homo sapiens
Lissens, W.; Zenati, A.; Liebaers, I.
Polyclonal antibodies against iduronate 2-sulphate sulphatase from human urine
Biochim. Biophys. Acta
801
365-371
1984
Homo sapiens
Di Natale, P.; Daniele, A.
Iduronate sulfatase from human placenta
Biochim. Biophys. Acta
839
258-261
1985
Homo sapiens
Constantopoulos, G.; Rees, S.; Cragg, B.G.; Barranger, J.A.; Brady, R.O.
Experimental animal model for mucopolysaccharidosis: suramin-induced glycosaminoglycan and sphingolipid accumulation in the rat
Proc. Natl. Acad. Sci. USA
77
3700-3704
1980
Rattus norvegicus
Bach, G.; Eisenberg, F., Jr.; Cantz, M.; Neufeld, E.F.
The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase
Proc. Natl. Acad. Sci. USA
70
2134-2138
1973
Homo sapiens
Sjoberg, I.; Fransson, L.A.; Matalon, R.; Dorfman, A.
Hunter's syndrome: a deficiency of L-idurono-sulfate sulfatase
Biochem. Biophys. Res. Commun.
54
1125-1132
1973
Homo sapiens
Bielicki, J.; Freeman, C.; Clements, P.R.; Hopwood, J.J.
Human liver iduronate-2-sulphatase. Purification, characterization and catalytic properties
Biochem. J.
271
75-86
1990
Homo sapiens
Bielicki, J.; Hopwood, J.J.; Wilson, P.J.; Anson, D.S.
Recombinant human iduronate-2-sulphatase: correction of mucopolysaccharidosis-type II fibroblasts and characterization of the purified enzyme
Biochem. J.
289
241-246
1993
Homo sapiens
Petruschka, L.; Zschiesche, M.; Bielicki, J.; Seidlitz, G.; Machill, G.; Hopwood, J.J.; Herrmann, F.H.
Mucopolysaccharidosis type II (Hunter syndrome): characterization of the iduronate-2-sulphatase in MPS II skin fibroblasts
J. Inherit. Metab. Dis.
17
89-92
1994
Homo sapiens
Millat, G.; Froissart, R.; Maire, I.; Bozon, D.
Characterization of iduronate sulphatase mutants affecting N-glycosylation sites and the cysteine-84 residue
Biochem. J.
326
243-247
1997
Homo sapiens
Coronado-Pons, I.; Novials, A.; Casas, S.; Clark, A.; Gomis, R.
Identification of iduronate-2-sulfatase (IDS) in mouse pancreatic islets
Am. J. Physiol.
10
1-33
2004
Mus musculus
-
Villani, G.R.; Daniele, A.; Balzano, N.; Di Natale, P.
Expression of five iduronate-2-sulfatase site-directed mutations
Biochim. Biophys. Acta
1501
71-80
2000
Homo sapiens
Bonuccelli, G.; Di Natale, P.; Corsolini, F.; Villani, G.; Regis, S.; Filocamo, M.
The effect of four mutations on the expression of iduronate-2-sulfatase in mucopolysaccharidosis type II
Biochim. Biophys. Acta
1537
233-238
2001
Homo sapiens
Daniele, A.; Tomanin, R.; Villani, G.R.; Zacchello, F.; Scarpa, M.; Di Natale, P.
Uptake of recombinant iduronate-2-sulfatase into neuronal and glial cells in vitro
Biochim. Biophys. Acta
1588
203-209
2002
Homo sapiens, Rattus norvegicus
Kim, C.H.; Hwang, H.Z.; Song, S.M.; Paik, K.H.; Kwon, E.K.; Moon, K.B.; Yoon, J.H.; Han, C.K.; Jin, D.K.
Mutational spectrum of the iduronate 2 sulfatase gene in 25 unrelated Korean Hunter syndrome patients: identification of 13 novel mutations
Hum. Mutat.
21
449-450
2003
Homo sapiens
Pan, D.; Jonsson, J.J.; Braun, S.E.; McIvor, R.S.; Whitley, C.B.
"Supercharged Cells" for delivery of recombinant human iduronate-2-sulfatase
Mol. Genet. Metab.
70
170-178
2000
Homo sapiens
Parkinson, E.J.; Muller, V.; Hopwood, J.J.; Brooks, D.A.
Iduronate-2-sulphatase protein detection in plasma from mucopolysaccharidosis type II patients
Mol. Genet. Metab.
81
58-64
2004
Homo sapiens
Parkinson-Lawrence, E.; Turner, C.; Hopwod, J.; Brooks, D.
Analysis of normal and mutant iduronate-2-sulphatase conformation
Biochem. J.
386
395-400
2005
Homo sapiens (P22304), Homo sapiens
Dean, C.J.; Bockmann, M.R.; Hopwood, J.J.; Brooks, D.A.; Meikle, P.J.
Detection of mucopolysaccharidosis type II by measurement of iduronate-2-sulfatase in dried blood spots and plasma samples
Clin. Chem.
52
643-649
2006
Homo sapiens
Bhattacharyya, S.; Tobacman, J.K.
Steroid sulfatase, arylsulfatases A and B, galactose-6-sulfatase, and iduronate sulfatase in mammary cells and effects of sulfated and non-sulfated estrogens on sulfatase activity
J. Steroid Biochem. Mol. Biol.
103
20-34
2007
Homo sapiens
Lin, S.P.; Chang, J.H.; Lee-Chen, G.J.; Lin, D.S.; Lin, H.Y.; Chuang, C.K.
Detection of Hunter syndrome (mucopolysaccharidosis type II) in Taiwanese: biochemical and linkage studies of the iduronate-2-sulfatase gene defects in MPS II patients and carriers
Clin. Chim. Acta
369
29-34
2006
Homo sapiens
Chang, J.; Lin, S.; Chuang, C.; Lee-Chen, G.
Characterization of a novel p.S305P and a known c.1006+5G>C splice site mutation in human iduronate-2-sulfatase associated with mucopolysaccharidosis type II
Clin. Chim. Acta
384
167-170
2007
Homo sapiens
Alves, S.; Mangas, M.; Prata, M.J.; Ribeiro, G.; Lopes, L.; Ribeiro, H.; Pinto-Basto, J.; Lima, M.R.; Lacerda, L.
Molecular characterization of Portuguese patients with mucopolysaccharidosis type II shows evidence that the IDS gene is prone to splicing mutations
J. Inherit. Metab. Dis.
29
743-754
2006
Homo sapiens
Sukegawa-Hayasaka, K.; Kato, Z.; Nakamura, H.; Tomatsu, S.; Fukao, T.; Kuwata, K.; Orii, T.; Kondo, N.
Effect of Hunter disease (mucopolysaccharidosis type II) mutations on molecular phenotypes of iduronate-2-sulfatase: enzymatic activity, protein processing and structural analysis
J. Inherit. Metab. Dis.
29
755-761
2006
Homo sapiens
Lualdi, S.; Pittis, M.G.; Regis, S.; Parini, R.; Allegri, A.E.; Furlan, F.; Bembi, B.; Filocamo, M.
Multiple cryptic splice sites can be activated by IDS point mutations generating misspliced transcripts
J. Mol. Med.
84
692-700
2006
Homo sapiens
Friso, A.; Tomanin, R.; Zanetti, A.; Mennuni, C.; Calvaruso, F.; La Monica, N.; Marin, O.; Zacchello, F.; Scarpa, M.
Gene therapy of Hunter syndrome: evaluation of the efficiency of muscle electro gene transfer for the production and release of recombinant iduronate-2-sulfatase (IDS)
Biochim. Biophys. Acta
1782
574-580
2008
Mus musculus
Lau, K.C.; Lam, C.W.
Molecular investigations of a novel iduronate-2-sulfatase mutant in a Chinese patient
Clin. Chim. Acta
392
8-10
2008
Homo sapiens
Keeratichamroen, S.; Ketudat Cairns, J.R.; Wattanasirichaigoon, D.; Wasant, P.; Ngiwsara, L.; Suwannarat, P.; Pangkanon, S.; Kuptanon, J.; Tanpaiboon, P.; Rujirawat, T.; Liammongkolkul, S.; Svasti, J.
Molecular analysis of the iduronate-2-sulfatase gene in Thai patients with Hunter syndrome
J. Inherit. Metab. Dis.
Suppl. 2
303-311
2008
Homo sapiens (P22304), Homo sapiens
Cordoba-Ruiz, H.; Poutou-Pinales, R.; Echeverri-Pena, O.; Algecira-Enciso, N.; Landazuri, P.; Saenz, H.; Barrera-Avellaneda, L.
Laboratory scale production of the human recombinant iduronate 2-sulfate sulfatase-Like from Pichia pastoris
Afr. J. Biotechnol.
8
1786-1792
2009
Homo sapiens
-
Polito, V.A.; Cosma, M.P.
IDS crossing of the blood-brain barrier corrects CNS defects in MPSII mice
Am. J. Hum. Genet.
85
296-301
2009
Homo sapiens
Piquer, S.; Casas, S.; Quesada, I.; Nadal, A.; Julia, M.; Novials, A.; Gomis, R.
Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis
Am. J. Physiol. Endocrinol. Metab.
297
E793-E801
2009
Homo sapiens
Lu, J.Z.; Hui, E.K.; Boado, R.J.; Pardridge, W.M.
Genetic engineering of a bifunctional IgG fusion protein with iduronate-2-sulfatase
Bioconjug. Chem.
21
151-156
2010
Homo sapiens
Lualdi, S.; Tappino, B.; Di Duca, M.; Dardis, A.; Anderson, C.J.; Biassoni, R.; Thompson, P.W.; Corsolini, F.; Di Rocco, M.; Bembi, B.; Regis, S.; Cooper, D.N.; Filocamo, M.
Enigmatic In Vivo iduronate-2-sulfatase (IDS) mutant transcript correction to wild-type in Hunter syndrome
Hum. Mutat.
31
E1261-E1285
2010
Homo sapiens
Jones, S.A.; Almassy, Z.; Beck, M.; Burt, K.; Clarke, J.T.; Giugliani, R.; Hendriksz, C.; Kroepfl, T.; Lavery, L.; Lin, S.P.; Malm, G.; Ramaswami, U.; Tincheva, R.; Wraith, J.E.; Wraith, J.E.
Mortality and cause of death in mucopolysaccharidosis type II-a historical review based on data from the Hunter Outcome Survey (HOS)
J. Inherit. Metab. Dis.
32
534-543
2009
Homo sapiens
Schwartz, I.V.; Pinto, L.L.; Breda, G.; Lima, L.; Ribeiro, M.G.; Mota, J.G.; Acosta, A.X.; Correia, P.; Horovitz, D.D.; Porciuncula, C.G.; Lipinski-Figueiredo, E.; Fett-Conte, A.C.; Sobrinho, R.P.; Norato, D.Y.; Paula, A.C.; Kim, C.A.; Duarte, A.R.; Boy, R.; Leistner-Segal, S.; Burin, M.G.; Giugliani, R.
Clinical and biochemical studies in mucopolysaccharidosis type II carriers
J. Inherit. Metab. Dis.
32
732-738
2009
Homo sapiens
Moro, E.; Tomanin, R.; Friso, A.; Modena, N.; Tiso, N.; Scarpa, M.; Argenton, F.
A novel functional role of iduronate-2-sulfatase in zebrafish early development
Matrix Biol.
29
43-50
2010
Danio rerio (A0ST40), Danio rerio
Araya, K.; Sakai, N.; Mohri, I.; Kagitani-Shimono, K.; Okinaga, T.; Hashii, Y.; Ohta, H.; Nakamichi, I.; Aozasa, K.; Taniike, M.; Ozono, K.
Localized donor cells in brain of a Hunter disease patient after cord blood stem cell transplantation
Mol. Genet. Metab.
98
255-263
2009
Homo sapiens
Okuyama, T.; Tanaka, A.; Suzuki, Y.; Ida, H.; Tanaka, T.; Cox, G.; Eto, Y.; Orii, T.
Japan Elaprase Treatment (JET) study: idursulfase enzyme replacement therapy in adult patients with attenuated Hunter syndrome (Mucopolysaccharidosis II, MPS II)
Mol. Genet. Metab.
99
18-25
2010
Homo sapiens
Muenzer, J.; Beck, M.; Eng, C.M.; Escolar, M.L.; Giugliani, R.; Guffon, N.H.; Harmatz, P.; Kamin, W.; Kampmann, C.; Koseoglu, S.T.; Link, B.; Martin, R.A.; Molter, D.W.; Munoz Rojas, M.V.; Ogilvie, J.W.; Parini, R.; Ramaswami, U.; Scarpa, M.; Schwartz, I.V.; Wood, R.E.; Wraith, E.
Multidisciplinary management of Hunter syndrome
Pediatrics
124
e1228-e1239
2009
Homo sapiens
Lu, J.Z.; Boado, R.J.; Hui, E.K.; Zhou, Q.H.; Pardridge, W.M.
Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein
Biotechnol. Bioeng.
108
1954-1964
2011
Homo sapiens
Sosa, A.C.; Espejo, A.J.; Rodriguez, E.A.; Lizaraso, L.M.; Rojas, A.; Guevara, J.; Echeverri, O.Y.; Barrera, L.A.
Development of a sandwich enzyme linked immunosorbent assay (ELISA) for the quantification of iduronate-2-sulfate sulfatase
J. Immunol. Methods
368
64-70
2011
Homo sapiens
Morales-Alvarez, E.D.; Rivera-Hoyos, C.M.; Baena-Moncada, A.M.; Landazuri, P.; Poutou-Pinales, R.A.; Saenz-Suarez, H.; Barrera, L.A.; Echeverri-Pena, O.Y.
Low-scale expression and purification of an active putative iduronate 2-sulfate sulfatase-Like enzyme from Escherichia coli K12
J. Microbiol.
51
213-221
2013
Homo sapiens
Zuber, Z.; RodzynskaSwiatowska, A.; Jurecka, A.; Tylki-Szymanska, A.
The effect of recombinant human iduronate-2-sulfatase (idursulfase) on growth in young patients with mucopolysaccharidosis type II
PLoS ONE
9
e85074
2014
Homo sapiens
Pimentel, N.; Rodriguez-Lopez, A.; Diaz, S.; Losada, J.C.; Diaz-Rincon, D.J.; Cardona, C.; Espejo-Mojica, A.J.; Ramirez, A.M.; Ruiz, F.; Landazuri, P.; Poutou-Pinales, R.A.; Cordoba-Ruiz, H.A.; Almeciga-Diaz, C.J.; Barrera-Avellaneda, L.A.
Production and characterization of a human lysosomal recombinant iduronate-2-sulfatase produced in Pichia pastoris
Biotechnol. Appl. Biochem.
65
655-664
2018
Homo sapiens (P22304), Homo sapiens
Lee, K.; Jun, S.H.; Song, S.H.; Park, H.D.; Park, K.U.; Song, J.
Direct assay of iduronate-2-sulfatase for Hunter disease using UPLC-tandem mass spectrometry and fluorogenic substrate
Clin. Biochem.
48
1350-1353
2015
Homo sapiens (P22304)
Mashima, R.; Ohira, M.; Okuyama, T.; Tatsumi, A.
Quantification of the enzyme activities of iduronate-2-sulfatase, N-acetylgalactosamine-6-sulfatase and N-acetylgalactosamine-4-sulfatase using liquid chromatography-tandem mass spectrometry
Mol. Genet. Metab. Rep.
14
36-40
2018
Homo sapiens (P22304)
Demydchuk, M.; Hill, C.; Zhou, A.; Bunkoczi, G.; Stein, P.; Marchesan, D.; Deane, J.; Read, R.
Insights into Hunter syndrome from the structure of iduronate-2-sulfatase
Nat. Commun.
8
15786
2017
Homo sapiens (P22304), Homo sapiens
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