Information on EC 3.1.6.13 - iduronate-2-sulfatase

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The expected taxonomic range for this enzyme is: Euteleostomi

EC NUMBER
COMMENTARY
3.1.6.13
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RECOMMENDED NAME
GeneOntology No.
iduronate-2-sulfatase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of sulfuric ester
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PATHWAY
KEGG Link
MetaCyc Link
Glycosaminoglycan degradation
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Metabolic pathways
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SYSTEMATIC NAME
IUBMB Comments
L-iduronate-2-sulfate 2-sulfohydrolase
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
2-sulfo-L-iduronate 2-sulfatase
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chondroitinsulfatase
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Hunter corrective factor
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in combination with L-iduronidase
IDS
A0ST40
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IDS
P22304
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IDS-Like
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iduronate 2-sulfatase
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iduronate 2-sulfate sulfatase-like
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iduronate sulfatase
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iduronate sulfatase
A0ST40
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iduronate sulfatase
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iduronate sulfate sulfatase
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iduronate-2-sulfatase
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iduronate-2-sulfatase
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iduronate-2-sulfate sulfatase
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iduronate-2-sulfate sulfatase
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iduronate-2-sulphatase
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iduronide-2-sulfate sulfatase
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idurono-2-sulfatase
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L-iduronate 2-sulfate sulfatase
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L-idurono sulfate sulfatase
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sulfatase, L-idurono-
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sulfo-L-iduronate sulfatase
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sulfoiduronate sulfohydrolase
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CAS REGISTRY NUMBER
COMMENTARY
50936-59-9
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
2 forms: A, B
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Manually annotated by BRENDA team
almost total absence of iduronate-2-sulfatase in patients with mucopolysaccharidosis type II compared with control
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Manually annotated by BRENDA team
multiple forms: A, B, C
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Manually annotated by BRENDA team
patients with mucopolysaccharidosis II
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Manually annotated by BRENDA team
patients with mucopolysaccharidosis type II
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Manually annotated by BRENDA team
patients with mucopolysaccharidosis type II, i.e. Hunter disease
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Manually annotated by BRENDA team
Portuguese patients with mucopolysaccharidosis type II
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Manually annotated by BRENDA team
several molecular species
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Manually annotated by BRENDA team
Taiwanese patients with mucopolysaccharidosis type II
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Manually annotated by BRENDA team