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Information on EC 3.1.3.48 - protein-tyrosine-phosphatase and Organism(s) Gallus gallus

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.48 protein-tyrosine-phosphatase
IUBMB Comments
Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2, non-specific protein-tyrosine kinase.
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This record set is specific for:
Gallus gallus
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The taxonomic range for the selected organisms is: Gallus gallus
The enzyme appears in selected viruses and cellular organisms
Synonyms
ptp1b, protein tyrosine phosphatase, shp-1, shp-2, tyrosine phosphatase, protein phosphatase 2a, acid phosphatase activity, mkp-1, cdc25a, ptpn22, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
70Z-SHP
-
-
-
-
Brain-derived phosphatase
-
-
-
-
BVP
-
-
-
-
CD148 antigen
-
-
-
-
CD45
-
-
-
-
CD45 antigen
-
-
-
-
Cdc25-like protein
-
-
-
-
CDK2-associated dual specificity phosphatase
-
-
-
-
Ch-1PTPase
-
-
-
-
chick retinal tyrosine phosphatase-2
-
-
CPTP1
-
-
-
-
Cryp-2
-
-
CRYP-2/PTPRO
-
-
CRYP-2/receptor-type tyrosine-protein phosphatase O
-
-
DLAR
-
-
-
-
Dual specificity phosphatase Cdc25A
-
-
-
-
Dual specificity phosphatase Cdc25B
-
-
-
-
Dual specificity phosphatase Cdc25C
-
-
-
-
Dual specificity protein phosphatase hVH1
-
-
-
-
Dual specificity protein phosphatase hVH2
-
-
-
-
Dual specificity protein phosphatase hVH3
-
-
-
-
Dual specificity protein phosphatase PYST1
-
-
-
-
Dual specificity protein phosphatase PYST2
-
-
-
-
Dual specificity protein phosphatase VHR
-
-
-
-
Dual-specificity tyrosine phosphatase TS-DSP6
-
-
-
-
Dual-specificity tyrosine phosphatase YVH1
-
-
-
-
ES cell phosphatase
-
-
-
-
HCP
-
-
-
-
Hematopoietic cell protein-tyrosine phosphatase
-
-
-
-
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
-
-
-
-
Hematopoietic protein-tyrosine phosphatase
-
-
-
-
HEPTP
-
-
-
-
HPTP beta-like tyrosine phosphatase
-
-
-
-
HPTP eta
-
-
-
-
hPTPE1
-
-
-
-
ICAAR
-
-
-
-
Islet cell autoantigen related protein
-
-
-
-
kinase associated phosphatase
-
-
-
-
L-CA
-
-
-
-
Late protein H1
-
-
-
-
LCA
-
-
-
-
LCA-related phosphatase
-
-
-
-
Leukocyte antigen related
-
-
-
-
Low molecular weight cytosolic acid phosphatase
-
-
-
-
LRP
-
-
-
-
Lymphoid phosphatase
-
-
-
-
LyP
-
-
-
-
M1851
-
-
-
-
MAP-kinase phosphatase CPG21
-
-
-
-
MEG
-
-
-
-
Mitosis initiation protein
-
-
-
-
Mitosis initiation protein MIH1
-
-
-
-
Mitotic inducer homolog
-
-
-
-
MKP-1 like protein tyrosine phosphatase
-
-
-
-
MPTP
-
-
-
-
MPTP-PEST
-
-
-
-
NC-PTPCOM1
-
-
-
-
Neural-specific protein-tyrosine phosphatase
-
-
-
-
ORF5
-
-
-
-
OST-PTP
-
-
-
-
P19-PTP
-
-
-
-
P80
-
-
-
-
PC12-PTP1
-
-
-
-
Phogrin
-
-
-
-
Phosphacan
-
-
-
-
phosphatase, phosphoprotein (phosphotyrosine)
-
-
-
-
phosphatase, phosphotyrosine
-
-
-
-
phosphoprotein phosphatase (phosphotyrosine)
-
-
-
-
phosphotyrosine histone phosphatase
-
-
-
-
phosphotyrosine phosphatase
-
-
-
-
Phosphotyrosine phosphatase 13
-
-
-
-
phosphotyrosine protein phosphatase
-
-
-
-
phosphotyrosylprotein phosphatase
-
-
-
-
protein phosphotyrosine phosphatase
-
-
-
-
protein tyrosine phosphatase
-
-
protein tyrosine phosphatase sigma
-
-
Protein tyrosine phosphatase-NP
-
-
-
-
Protein-protein-tyrosine phosphatase HA2
-
-
-
-
Protein-tyrosine phosphatase 1B
-
-
-
-
Protein-tyrosine phosphatase 1C
-
-
-
-
Protein-tyrosine phosphatase 1E
-
-
-
-
Protein-tyrosine phosphatase 2C
-
-
-
-
Protein-tyrosine phosphatase 2E
-
-
-
-
Protein-tyrosine phosphatase 3CH134
-
-
-
-
Protein-tyrosine phosphatase CL100
-
-
-
-
Protein-tyrosine phosphatase D1
-
-
-
-
Protein-tyrosine phosphatase ERP
-
-
-
-
Protein-tyrosine phosphatase G1
-
-
-
-
Protein-tyrosine phosphatase H1
-
-
-
-
Protein-tyrosine phosphatase LC-PTP
-
-
-
-
Protein-tyrosine phosphatase MEG1
-
-
-
-
Protein-tyrosine phosphatase MEG2
-
-
-
-
Protein-tyrosine phosphatase P19
-
-
-
-
Protein-tyrosine phosphatase PCPTP1
-
-
-
-
Protein-tyrosine phosphatase pez
-
-
-
-
Protein-tyrosine phosphatase PTP-RL10
-
-
-
-
Protein-tyrosine phosphatase PTP36
-
-
-
-
Protein-tyrosine phosphatase PTPL1
-
-
-
-
Protein-tyrosine phosphatase striatum-enriched
-
-
-
-
Protein-tyrosine phosphatase SYP
-
-
-
-
Protein-tyrosine-phosphatase SL
-
-
-
-
Protein-tyrosine-phosphate phosphohydrolase
-
-
-
-
PTP IA-2beta
-
-
-
-
PTP-1B
-
-
-
-
PTP-1C
-
-
-
-
PTP-1D
-
-
-
-
PTP-2C
-
-
-
-
PTP-BAS
-
-
-
-
PTP-E1
-
-
-
-
PTP-H1
-
-
-
-
PTP-HA2
-
-
-
-
PTP-NP
-
-
-
-
PTP-SH2beta
-
-
-
-
PTP1C
-
-
-
-
PTP1D
-
-
-
-
PTP2C
-
-
-
-
PTPase YVH1
-
-
-
-
PTPase-MEG1
-
-
-
-
PTPase-MEG2
-
-
-
-
PTPG1
-
-
-
-
PTPN6
-
-
-
-
PTPNE6
-
-
-
-
PTPsigma
-
-
PY protein phosphatase
-
-
-
-
R-PTP-alpha
-
-
-
-
R-PTP-beta
-
-
-
-
R-PTP-delta
-
-
-
-
R-PTP-epsilon
-
-
-
-
R-PTP-eta
-
-
-
-
R-PTP-gamma
-
-
-
-
R-PTP-kappa
-
-
-
-
R-PTP-mu
-
-
-
-
R-PTP-zeta
-
-
-
-
receptor protein tyrosine phosphatase
-
-
Receptor-linked protein-tyrosine phosphatase 10D
-
-
-
-
Receptor-linked protein-tyrosine phosphatase 99A
-
-
-
-
RNA/RNP complex-intereracting phosphatase
-
-
-
-
ROL B protein
-
-
-
-
RPTPalpha
-
-
-
-
SH-PTP1
-
-
-
-
SH-PTP2
-
-
-
-
SH-PTP3
-
-
-
-
SHP
-
-
-
-
Small tyrosine phosphatase
-
-
-
-
Small, acidic phosphotyrosine protein phosphatase
-
-
-
-
STEP
-
-
-
-
String protein
-
-
-
-
Syp
-
-
-
-
T-cell protein-tyrosine phosphatase
-
-
-
-
T-DSP11
-
-
-
-
T200
-
-
-
-
TCPTP
-
-
-
-
Testis-and skeletal-muscle-specific DSP
-
-
-
-
tyrosine O-phosphate phosphatase
-
-
-
-
Tyrosine phosphatase CBPTP
-
-
-
-
tyrosylprotein phosphatase
-
-
-
-
[phosphotyrosine]protein phosphatase
-
-
-
-
additional information
-
CRYP-2 is identical in sequence to the human glomerular epithelial protein-1
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
protein-tyrosine-phosphate phosphohydrolase
Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2, non-specific protein-tyrosine kinase.
CAS REGISTRY NUMBER
COMMENTARY hide
79747-53-8
-
97162-86-2
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
show the reaction diagram
-
-
-
-
?
6,8-difluoro-4-methylumbelliferyl phosphate + H2O
6,8-difluoro-4-methylumbelliferone + phosphate
show the reaction diagram
-
-
-
-
?
phosphothreonine + H2O
threonine + phosphate
show the reaction diagram
-
-
-
-
?
phosphotyrosine + H2O
tyrosine + phosphate
show the reaction diagram
-
-
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-nitrocatechol sulfate
-
applied from from bare and amine functionalized mesoporous silica, MCM-48, and mesoporous alumina for sustained delivery, competitive inhibition, kinetics, overview
formaldehyde
-
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
glutathione
-
reducing agent required
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
25
4-nitrophenyl phosphate
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7
-
assay at
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 7
-
-
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
CRYP-2 is involved in hepatic carcinomas, inhibition of CRYP-2 is of tremendous therapeutic importance
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DUS29_CHICK
214
0
24322
Swiss-Prot
other Location (Reliability: 2)
PTPRG_CHICK
1422
1
159767
Swiss-Prot
Secretory Pathway (Reliability: 1)
DUS4_CHICK
375
0
41052
Swiss-Prot
other Location (Reliability: 3)
EYA1_CHICK
119
0
13549
Swiss-Prot
other Location (Reliability: 5)
EYA3_CHICK
119
0
13704
Swiss-Prot
other Location (Reliability: 4)
EYA4_CHICK
119
0
13340
Swiss-Prot
other Location (Reliability: 5)
PGP_CHICK
312
0
32996
Swiss-Prot
other Location (Reliability: 5)
PTPRS_CHICK
1516
1
170604
Swiss-Prot
Secretory Pathway (Reliability: 1)
PTPRU_CHICK
1434
1
161679
Swiss-Prot
Secretory Pathway (Reliability: 1)
PPAC_CHICK
158
0
18196
Swiss-Prot
other Location (Reliability: 3)
PTN11_CHICK
593
0
67983
Swiss-Prot
other Location (Reliability: 5)
PTN1_CHICK
434
1
50334
Swiss-Prot
other Location (Reliability: 1)
PTPRJ_CHICK
1406
1
154214
Swiss-Prot
Secretory Pathway (Reliability: 1)
Q91969_CHICK
807
2
90736
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PFJ3_CHICK
363
0
40681
TrEMBL
other Location (Reliability: 5)
A0A3Q2UEE4_CHICK
1491
0
167499
TrEMBL
Secretory Pathway (Reliability: 1)
E1C5H0_CHICK
1185
0
135576
TrEMBL
Mitochondrion (Reliability: 2)
F1NSL6_CHICK
2308
1
256363
TrEMBL
other Location (Reliability: 4)
A0A1D5NTU4_CHICK
552
0
59994
TrEMBL
other Location (Reliability: 1)
A0A1D5PFX7_CHICK
1963
1
219793
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5NTM8_CHICK
1422
1
159797
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q3A785_CHICK
1604
1
180075
TrEMBL
other Location (Reliability: 4)
A0A1L1RU24_CHICK
592
0
68042
TrEMBL
other Location (Reliability: 4)
A0A3Q2UI20_CHICK
1155
0
129104
TrEMBL
other Location (Reliability: 2)
A0A1D5PHX3_CHICK
1488
1
167476
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2TUL9_CHICK
2376
1
257159
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5PW29_CHICK
1521
1
170903
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PR76_CHICK
1237
2
139342
TrEMBL
Secretory Pathway (Reliability: 1)
F1NA27_CHICK
1387
1
154682
TrEMBL
other Location (Reliability: 3)
A0A3Q2UDW7_CHICK
1500
1
168727
TrEMBL
Secretory Pathway (Reliability: 1)
F1N843_CHICK
604
0
68367
TrEMBL
other Location (Reliability: 5)
F1NT98_CHICK
423
0
49394
TrEMBL
other Location (Reliability: 2)
A0A3Q2TXW1_CHICK
2289
1
247903
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5PF56_CHICK
1519
0
170797
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2UAX3_CHICK
334
0
36200
TrEMBL
other Location (Reliability: 4)
F1NIB9_CHICK
207
0
23131
TrEMBL
other Location (Reliability: 2)
F1NVR5_CHICK
1191
0
135585
TrEMBL
Mitochondrion (Reliability: 2)
A0A3Q2U274_CHICK
487
0
55472
TrEMBL
Mitochondrion (Reliability: 3)
Q5F3I5_CHICK
604
0
68366
TrEMBL
other Location (Reliability: 5)
F1ND27_CHICK
574
0
63202
TrEMBL
other Location (Reliability: 1)
E1C2A9_CHICK
1257
0
140567
TrEMBL
other Location (Reliability: 5)
A0A1D5PTH8_CHICK
1711
1
191373
TrEMBL
Secretory Pathway (Reliability: 1)
F1NPL5_CHICK
534
0
59092
TrEMBL
other Location (Reliability: 2)
Q5ZHY7_CHICK
557
0
62223
TrEMBL
Mitochondrion (Reliability: 2)
F1NHM0_CHICK
972
0
111253
TrEMBL
other Location (Reliability: 4)
Q5F335_CHICK
382
0
42387
TrEMBL
other Location (Reliability: 4)
A0A1D5PKK4_CHICK
1220
0
136331
TrEMBL
other Location (Reliability: 5)
A0A3Q3AJM7_CHICK
1497
0
168270
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P6N5_CHICK
1916
1
214806
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5NXI7_CHICK
645
0
70119
TrEMBL
other Location (Reliability: 1)
A0A1D5P6Q1_CHICK
1219
0
139207
TrEMBL
Mitochondrion (Reliability: 2)
A0A1D5PX34_CHICK
1450
1
163503
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2UCN1_CHICK
606
0
68456
TrEMBL
other Location (Reliability: 3)
F1NMQ6_CHICK
1268
2
143025
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5P441_CHICK
1162
2
131725
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P2D6_CHICK
1902
1
212642
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P4D3_CHICK
592
0
68086
TrEMBL
other Location (Reliability: 3)
A0A1D5PIJ8_CHICK
868
0
99470
TrEMBL
other Location (Reliability: 2)
A0A1D5NUR0_CHICK
577
0
62918
TrEMBL
other Location (Reliability: 1)
A0A1D5P2H1_CHICK
617
0
67251
TrEMBL
other Location (Reliability: 2)
A0A1D5PQ87_CHICK
1496
1
168300
TrEMBL
Secretory Pathway (Reliability: 1)
F1P3J3_CHICK
1455
2
159889
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2UIN7_CHICK
1920
1
215233
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2TSZ6_CHICK
992
2
112283
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1L1S114_CHICK
1205
2
136206
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PMV7_CHICK
1228
0
137262
TrEMBL
other Location (Reliability: 2)
A0A3Q2TZR5_CHICK
1512
1
170054
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1I7Q402_CHICK
475
1
54882
TrEMBL
other Location (Reliability: 2)
A0A3Q2UK93_CHICK
570
0
65175
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5PW72_CHICK
1917
1
214981
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P9Z1_CHICK
158
0
18086
TrEMBL
other Location (Reliability: 3)
A0A3Q2U9H7_CHICK
555
0
61835
TrEMBL
Mitochondrion (Reliability: 2)
F1P3K6_CHICK
525
2
60136
TrEMBL
other Location (Reliability: 2)
E1BQV8_CHICK
1141
0
127608
TrEMBL
other Location (Reliability: 1)
F1P225_CHICK
202
0
22256
TrEMBL
other Location (Reliability: 3)
A0A1D5NXU4_CHICK
1420
1
159817
TrEMBL
Secretory Pathway (Reliability: 1)
E1BSB5_CHICK
207
0
23135
TrEMBL
Mitochondrion (Reliability: 3)
A0A3Q3AQ02_CHICK
434
1
50417
TrEMBL
other Location (Reliability: 1)
A0A3Q2TRV2_CHICK
1951
1
218287
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PZA0_CHICK
192
0
21253
TrEMBL
other Location (Reliability: 2)
A0A3Q2TX63_CHICK
1469
0
165345
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PXT4_CHICK
499
0
56791
TrEMBL
Mitochondrion (Reliability: 3)
F1N8A2_CHICK
1848
0
206933
TrEMBL
Secretory Pathway (Reliability: 4)
A0A1D5P5S2_CHICK
385
0
42315
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5P2X5_CHICK
658
1
73981
TrEMBL
Secretory Pathway (Reliability: 4)
A0A3Q2UHA8_CHICK
596
0
65116
TrEMBL
other Location (Reliability: 1)
A0A3Q2U6C7_CHICK
2415
1
260841
TrEMBL
Mitochondrion (Reliability: 5)
A0A1D5PB94_CHICK
1197
0
133922
TrEMBL
other Location (Reliability: 1)
F1N842_CHICK
309
0
33321
TrEMBL
other Location (Reliability: 3)
A0A1D5PIN8_CHICK
1916
1
214706
TrEMBL
Secretory Pathway (Reliability: 1)
F1NQ49_CHICK
1960
1
219464
TrEMBL
Secretory Pathway (Reliability: 1)
E1BWF6_CHICK
914
0
104295
TrEMBL
Mitochondrion (Reliability: 2)
A0A1D5NV24_CHICK
1915
1
214330
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PPX9_CHICK
616
0
66850
TrEMBL
other Location (Reliability: 1)
A0A1D5NUZ8_CHICK
622
0
67632
TrEMBL
other Location (Reliability: 1)
A0A1D5PRW6_CHICK
1191
2
134792
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PPA5_CHICK
1522
1
171235
TrEMBL
Secretory Pathway (Reliability: 1)
E1BY90_CHICK
195
0
22127
TrEMBL
Mitochondrion (Reliability: 2)
A0A1D5PLR9_CHICK
1445
2
161895
TrEMBL
Secretory Pathway (Reliability: 2)
A0A1D5PT51_CHICK
1924
1
215179
TrEMBL
Secretory Pathway (Reliability: 1)
F1P209_CHICK
603
0
67997
TrEMBL
other Location (Reliability: 4)
A0A3Q2UIM0_CHICK
528
0
58372
TrEMBL
other Location (Reliability: 1)
A0A3Q2UB51_CHICK
1645
1
184418
TrEMBL
other Location (Reliability: 4)
A0A3Q2UDY1_CHICK
478
0
54165
TrEMBL
Mitochondrion (Reliability: 3)
A0A1D5P3J6_CHICK
596
0
65147
TrEMBL
other Location (Reliability: 2)
A0A1D5PC43_CHICK
631
0
69994
TrEMBL
Secretory Pathway (Reliability: 4)
A0A3Q2UET2_CHICK
639
0
72140
TrEMBL
other Location (Reliability: 5)
A0A1D5PKL5_CHICK
1494
1
168387
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P2W7_CHICK
1843
1
205929
TrEMBL
Secretory Pathway (Reliability: 1)
D5K9Y4_CHICK
460
0
52532
TrEMBL
Mitochondrion (Reliability: 3)
Q91976_CHICK
1237
2
139320
TrEMBL
Secretory Pathway (Reliability: 1)
D5K9Y5_CHICK
603
0
67904
TrEMBL
other Location (Reliability: 4)
E1C6Q8_CHICK
2302
1
249373
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P273_CHICK
2308
1
254826
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P4W3_CHICK
1450
1
163792
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5P463_CHICK
369
0
39975
TrEMBL
other Location (Reliability: 3)
A0A3Q2U5T9_CHICK
988
0
112443
TrEMBL
other Location (Reliability: 2)
Q5ZMF1_CHICK
604
0
68391
TrEMBL
other Location (Reliability: 5)
F1N897_CHICK
1921
1
214714
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PWT5_CHICK
1914
1
214652
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PBZ9_CHICK
2119
0
237645
TrEMBL
Secretory Pathway (Reliability: 3)
A0A3Q2TXT9_CHICK
1507
0
169369
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q3AJR6_CHICK
1221
0
135652
TrEMBL
Mitochondrion (Reliability: 2)
F1NVB1_CHICK
1186
2
133669
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1L1RRB0_CHICK
867
1
96843
TrEMBL
Mitochondrion (Reliability: 4)
A0A3Q2U2J4_CHICK
1481
0
166561
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2U428_CHICK
388
0
42926
TrEMBL
other Location (Reliability: 2)
A0A1D5PS22_CHICK
1217
0
136145
TrEMBL
other Location (Reliability: 1)
A0A3Q2U9B2_CHICK
1858
1
208301
TrEMBL
Secretory Pathway (Reliability: 1)
Q7T2L9_CHICK
382
0
42528
TrEMBL
other Location (Reliability: 2)
Q5ZL46_CHICK
319
0
36081
TrEMBL
other Location (Reliability: 5)
A0A3Q3AWY5_CHICK
421
1
48807
TrEMBL
other Location (Reliability: 2)
Q98945_CHICK
1267
2
142621
TrEMBL
Mitochondrion (Reliability: 5)
R4GJB9_CHICK
1403
1
153844
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PX53_CHICK
1936
1
216096
TrEMBL
Secretory Pathway (Reliability: 1)
A3FB57_CHICK
1793
1
200915
TrEMBL
other Location (Reliability: 2)
A0A1D5PI23_CHICK
184
0
20695
TrEMBL
other Location (Reliability: 1)
A0A1D5PGP0_CHICK
625
0
68095
TrEMBL
other Location (Reliability: 2)
A0A1D5NWI8_CHICK
1916
1
214090
TrEMBL
Secretory Pathway (Reliability: 1)
R4GK00_CHICK
484
1
55178
TrEMBL
Mitochondrion (Reliability: 3)
F1NCC5_CHICK
375
0
41053
TrEMBL
other Location (Reliability: 3)
Q9YI56_CHICK
534
0
59111
TrEMBL
other Location (Reliability: 2)
F1NPE8_CHICK
821
2
92178
TrEMBL
Secretory Pathway (Reliability: 3)
A0A452J7R1_CHICK
1516
1
170581
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3Q2TZZ7_CHICK
1904
1
213089
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1D5PY31_CHICK
526
0
59369
TrEMBL
Mitochondrion (Reliability: 4)
PDB
SCOP
CATH
UNIPROT
ORGANISM
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
180000
-
2D-SDS-PAGE
35000
-
pp2A1, gel filtration
90000
-
2 * 90000, 2D-SDS-PAGE and cysteine cross-linking
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
homodimer
-
2 * 90000, 2D-SDS-PAGE and cysteine cross-linking
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in HEK293T cells
-
expression in Escherichia coli
-
expression in Escherichia coli strain BL21(DE3)
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Foulkes, J.G.
Phosphotyrosyl-protein phosphatases
Curr. Top. Microbiol. Immunol.
107
163-180
1983
Gallus gallus, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Lau, K.H.W.; Farley, J.R.; Baylink, D.J.
Phosphotyrosyl protein phosphatases
Biochem. J.
257
23-36
1989
Gallus gallus, Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Kim, C.W.; Jung, E.J.; Kang, Y.S.
Cloning and characterization of a chicken protein tyrosine phosphatase, CPTP1
Exp. Mol. Med.
28
207-213
1996
Gallus gallus
-
Manually annotated by BRENDA team
Lee, S.; Faux, C.; Nixon, J.; Alete, D.; Chilton, J.; Hawadle, M.; Stoker, A.W.
Dimerization of protein tyrosine phosphatase sigma governs both ligand binding and isoform specificity
Mol. Cell. Biol.
27
1795-1808
2007
Gallus gallus
Manually annotated by BRENDA team
Kapoor, S.; Girish, T.S.; Mandal, S.S.; Gopal, B.; Bhattacharyya, A.J.
Inhibition of a protein tyrosine phosphatase using mesoporous oxides
J. Phys. Chem. B
114
3117-3121
2010
Gallus gallus
Manually annotated by BRENDA team