Information on EC 3.1.3.3 - phosphoserine phosphatase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

EC NUMBER
COMMENTARY
3.1.3.3
-
RECOMMENDED NAME
GeneOntology No.
phosphoserine phosphatase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Glycine, serine and threonine metabolism
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Metabolic pathways
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Methane metabolism
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Microbial metabolism in diverse environments
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serine biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
O-phosphoserine phosphohydrolase
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
3-phosphoserine phosphatase
-
-
-
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CTD phosphatase fcp1
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-
-
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HPSP
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-
L-phosphoserine phosphatase
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O-phosphoserine phosphohydrolase
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-
-
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phosphatase, phosphoserine
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-
-
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phosphoserine phosphatase
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phosphoserine phosphatase
Q99LS3
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phosphoserine phosphatase
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phosphoserine phosphatase
Q5M819
-
phosphoserine:homoserine phosphotransferase
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-
PSP
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-
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PSPase
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-
-
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PSPH
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SerB653
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is a HAD-family phosphatase
CAS REGISTRY NUMBER
COMMENTARY
9025-73-4
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IC50 VALUE [mM]
IC50 VALUE [mM] Maximum
INHIBITOR
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
4.4
-
EDTA
-
at 30C, in 50 mM Tris (pH 7.5), with 5 mM MgCl2
1.3
-
Na3VO4
-
at 30C, in 50 mM Tris (pH 7.5), with 5 mM MgCl2
5.9
-
NaF
-
at 30C, in 50 mM Tris (pH 7.5), with 5 mM MgCl2
0.005
-
okadaic acid
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IC50: above 0.005 mM, at 30C, in 50 mM Tris (pH 7.5), with 5 mM MgCl2
pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6.4
9.2
-
fluoride chemical shifts constant throughout the pH range examined
PDB
SCOP
CATH
ORGANISM
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Mycobacterium avium (strain 104)
Thermococcus onnurineus (strain NA1)
Thermococcus onnurineus (strain NA1)