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Information on EC 3.1.3.16 - protein-serine/threonine phosphatase and Organism(s) Xenopus tropicalis

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.16 protein-serine/threonine phosphatase
IUBMB Comments
A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48 protein-tyrosine-phosphatase). The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1, phosphoamidase).
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Xenopus tropicalis
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The taxonomic range for the selected organisms is: Xenopus tropicalis
The enzyme appears in selected viruses and cellular organisms
Synonyms
calcineurin, protein phosphatase, pac-1, dusp1, dusp6, serine/threonine phosphatase, pp2ac, ppm1d, phosphoprotein phosphatase, laforin, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3-hydroxy 3-methylglutaryl CoenzymeA reductase phosphatase
-
-
-
-
Aspergillus awamori acid protein phosphatase
-
-
-
-
BCKDH phosphatase
-
-
-
-
branched-chain alpha-keto acid dehydrogenase phosphatase
-
-
-
-
calcineurin
-
-
-
-
Calcineurin A1
-
-
-
-
Calcineurin A2
-
-
-
-
CaM-kinase phosphatase
-
-
-
-
CaMKPase
-
-
-
-
casein phosphatase
-
-
-
-
DRES10
-
-
-
-
Fibroblast growth factor inducible protein 13
-
-
-
-
FIN13
-
-
-
-
Flap wing protein
-
-
-
-
HMG-CoA reductase phosphatase
-
-
-
-
Magnesium-dependent calcium inhibitable phosphatase
-
-
-
-
MCPP
-
-
-
-
Microtubule star protein
-
-
-
-
phosphatase 2A
-
-
-
-
phosphatase 2B
-
-
-
-
phosphatase C-II
-
-
-
-
Phosphatase esp1
-
-
-
-
phosphatase H-II
-
-
-
-
phosphatase I
-
-
-
-
phosphatase IB
-
-
-
-
phosphatase II
-
-
-
-
phosphatase III
-
-
-
-
phosphatase IV
-
-
-
-
phosphatase SP
-
-
-
-
phosphoprotein phosphatase
-
-
-
-
phosphopyruvate dehydrogenase phosphatase
-
-
-
-
phosphospectrin phosphatase
-
-
-
-
PK-Pase
-
-
-
-
polycation modulated (PCM-) phosphatase
-
-
-
-
PP-1A
-
-
-
-
PP-1B
-
-
-
-
PP-1G
-
-
-
-
PP2A-alpha
-
-
-
-
PP2A-beta
-
-
-
-
PP2C
-
-
-
-
PP2C-alpha
-
-
-
-
PP2C-beta
-
-
-
-
PP2C-delta
-
-
-
-
PP2C-gamma
-
-
-
-
Pp4
-
-
-
-
PP5
-
-
-
-
PP6
-
-
-
-
PPEF
-
-
-
-
PPN
-
-
-
-
PPT
-
-
-
-
protein D phosphatase
-
-
-
-
protein phosphatase
-
-
-
-
Protein phosphatase 1A
-
-
-
-
Protein phosphatase 1B
-
-
-
-
Protein phosphatase 1C
-
-
-
-
Protein phosphatase magnesium-dependent 1 delta
-
-
-
-
Protein phosphatase magnesium-dependent 1 gamma
-
-
-
-
Protein phosphatase with EF calcium-binding domain
-
-
-
-
PSPase
-
-
-
-
Retinal degeneration C protein
-
-
-
-
Suppressor protein SDS21
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
protein-serine/threonine-phosphate phosphohydrolase
A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48 protein-tyrosine-phosphatase). The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1, phosphoamidase).
CAS REGISTRY NUMBER
COMMENTARY hide
9025-75-6
-
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CPPED_XENTR
311
0
35579
Swiss-Prot
Mitochondrion (Reliability: 4)
DUS22_XENTR
209
0
23453
Swiss-Prot
other Location (Reliability: 4)
PP1B_XENTR
327
0
37173
Swiss-Prot
other Location (Reliability: 2)
CNEP1_XENTR
244
1
28149
Swiss-Prot
Mitochondrion (Reliability: 5)
UBCP1_XENTR
318
0
36854
Swiss-Prot
other Location (Reliability: 3)
PPM1H_XENTR
510
0
56461
Swiss-Prot
Mitochondrion (Reliability: 5)
DUS29_XENTR
209
0
23746
Swiss-Prot
other Location (Reliability: 2)
PGAM5_XENTR
278
1
31211
Swiss-Prot
Secretory Pathway (Reliability: 5)
PPIG_XENTR
323
0
36956
Swiss-Prot
other Location (Reliability: 2)
PP4C_XENTR
307
0
35123
Swiss-Prot
other Location (Reliability: 1)
A0A6I8SW81_XENTR
511
0
57673
TrEMBL
other Location (Reliability: 4)
Q562D4_XENTR
344
0
38098
TrEMBL
other Location (Reliability: 1)
A0A6I8SEW8_XENTR
688
0
78806
TrEMBL
other Location (Reliability: 4)
A0A6I8QF30_XENTR
531
0
60174
TrEMBL
other Location (Reliability: 4)
A0A6I8QA81_XENTR
500
0
56816
TrEMBL
other Location (Reliability: 2)
A0A6I8Q6S0_XENTR
1416
0
158519
TrEMBL
other Location (Reliability: 4)
A0A6I8R1F0_XENTR
265
0
29941
TrEMBL
other Location (Reliability: 2)
Q28F83_XENTR
388
0
42730
TrEMBL
other Location (Reliability: 2)
Q6DIG6_XENTR
589
0
65430
TrEMBL
other Location (Reliability: 2)
F6V3S9_XENTR
278
0
31452
TrEMBL
Secretory Pathway (Reliability: 4)
A0A6I8QDA0_XENTR
513
0
58554
TrEMBL
other Location (Reliability: 2)
A0A6I8RHJ8_XENTR
227
0
25849
TrEMBL
other Location (Reliability: 2)
A0A803JG79_XENTR
218
0
24410
TrEMBL
other Location (Reliability: 1)
F6U9J0_XENTR
625
0
71498
TrEMBL
other Location (Reliability: 4)
A0A6I8R099_XENTR
522
0
59093
TrEMBL
other Location (Reliability: 4)
F6YU71_XENTR
491
0
56086
TrEMBL
other Location (Reliability: 2)
A0A6I8SYP1_XENTR
522
0
59657
TrEMBL
other Location (Reliability: 2)
A0A803K6U5_XENTR
546
0
60230
TrEMBL
other Location (Reliability: 1)
Q28EK7_XENTR
511
0
58157
TrEMBL
other Location (Reliability: 4)
B1H2U0_XENTR
402
0
47064
TrEMBL
other Location (Reliability: 3)
F7AMF9_XENTR
271
0
30513
TrEMBL
other Location (Reliability: 2)
A0A6I8R0T2_XENTR
1419
0
159186
TrEMBL
other Location (Reliability: 4)
F6ZZU2_XENTR
297
0
32256
TrEMBL
Mitochondrion (Reliability: 3)
A0A6I8S433_XENTR
316
0
36334
TrEMBL
other Location (Reliability: 2)
A0A8J0QYE2_XENTR
1393
0
156192
TrEMBL
other Location (Reliability: 5)
B1H139_XENTR
326
0
37198
TrEMBL
other Location (Reliability: 1)
Q6P365_XENTR
309
0
35607
TrEMBL
other Location (Reliability: 1)
Q5CZZ4_XENTR
375
0
42299
TrEMBL
Mitochondrion (Reliability: 2)
F7DHV8_XENTR
260
0
29487
TrEMBL
other Location (Reliability: 1)
A0A8J0SJP1_XENTR
189
0
21096
TrEMBL
other Location (Reliability: 4)
A0A803JQD7_XENTR
325
0
37216
TrEMBL
other Location (Reliability: 1)
A0A8J0PJE6_XENTR
570
0
63419
TrEMBL
other Location (Reliability: 3)
A0A6I8R0I5_XENTR
520
0
58761
TrEMBL
other Location (Reliability: 4)
B7ZT65_XENTR
311
0
35579
TrEMBL
Mitochondrion (Reliability: 4)
Q6GLD5_XENTR
369
0
40336
TrEMBL
other Location (Reliability: 3)
A0A6I8PVM3_XENTR
519
0
58744
TrEMBL
other Location (Reliability: 5)
Q28HA6_XENTR
369
0
40309
TrEMBL
other Location (Reliability: 3)
B1H163_XENTR
194
0
22659
TrEMBL
Mitochondrion (Reliability: 4)
A0A1B8XWE3_XENTR
307
0
35123
TrEMBL
other Location (Reliability: 1)
Q6VN50_XENTR
170
0
19300
TrEMBL
other Location (Reliability: 1)
Q6GLE6_XENTR
309
0
35578
TrEMBL
other Location (Reliability: 1)
A0A6I8Q966_XENTR
531
0
60092
TrEMBL
other Location (Reliability: 2)
A4IFW0_XENTR
524
0
59766
TrEMBL
other Location (Reliability: 3)
A0A6I8S5F5_XENTR
513
1
58964
TrEMBL
Secretory Pathway (Reliability: 1)
A0A803KA67_XENTR
260
0
29465
TrEMBL
Mitochondrion (Reliability: 5)
A0A6I8T0Z1_XENTR
321
0
36902
TrEMBL
other Location (Reliability: 3)
A0A803JET8_XENTR
209
0
23733
TrEMBL
other Location (Reliability: 2)
A0A6I8R1R1_XENTR
1417
0
158606
TrEMBL
other Location (Reliability: 4)
Q66JH6_XENTR
387
0
42736
TrEMBL
other Location (Reliability: 2)
F6UEJ5_XENTR
511
0
58166
TrEMBL
other Location (Reliability: 4)
A0A6I8Q638_XENTR
258
0
28882
TrEMBL
other Location (Reliability: 2)
A0A803KLM8_XENTR
257
0
28411
TrEMBL
other Location (Reliability: 4)
Q28E94_XENTR
378
0
41946
TrEMBL
other Location (Reliability: 2)
F7BTI8_XENTR
190
0
21604
TrEMBL
Mitochondrion (Reliability: 5)
Q28GT8_XENTR
305
0
35159
TrEMBL
other Location (Reliability: 1)
F6QEE8_XENTR
321
0
37117
TrEMBL
other Location (Reliability: 3)
A0A6I8RB06_XENTR
376
0
41647
TrEMBL
other Location (Reliability: 2)
F7BI71_XENTR
222
0
25820
TrEMBL
other Location (Reliability: 1)
F6X686_XENTR
316
0
36605
TrEMBL
Secretory Pathway (Reliability: 3)
A0A6I8PYR0_XENTR
264
0
29809
TrEMBL
other Location (Reliability: 1)
F6WBL1_XENTR
700
0
80604
TrEMBL
other Location (Reliability: 2)
B0JZY6_XENTR
126
0
14250
TrEMBL
Mitochondrion (Reliability: 4)
A0A803JWQ7_XENTR
209
0
23435
TrEMBL
other Location (Reliability: 1)
A0A8J0QTX7_XENTR
184
0
21011
TrEMBL
other Location (Reliability: 2)
A0A6I8SD23_XENTR
510
0
57634
TrEMBL
Secretory Pathway (Reliability: 3)
A0A6I8Q749_XENTR
1003
0
114014
TrEMBL
Secretory Pathway (Reliability: 4)
A0A8J1JS41_XENTR
781
0
89926
TrEMBL
Mitochondrion (Reliability: 5)
A0A8J0SAX0_XENTR
530
0
59804
TrEMBL
other Location (Reliability: 4)
B0BLZ8_XENTR
521
0
58716
TrEMBL
other Location (Reliability: 4)
A0A8J0QWA7_XENTR
1392
0
156105
TrEMBL
other Location (Reliability: 5)
A0A8J1JWH8_XENTR
182
0
20594
TrEMBL
other Location (Reliability: 3)
A0A6I8QBS8_XENTR
368
0
42896
TrEMBL
other Location (Reliability: 4)
A0A6I8QPP3_XENTR
222
0
25849
TrEMBL
other Location (Reliability: 1)
Q28F82_XENTR
567
0
63118
TrEMBL
other Location (Reliability: 4)
A0A6I8SEV4_XENTR
500
0
56989
TrEMBL
other Location (Reliability: 2)
F6XUZ3_XENTR
1453
0
162984
TrEMBL
Mitochondrion (Reliability: 5)
Q68EP0_XENTR
493
0
56247
TrEMBL
other Location (Reliability: 1)
F6UFW2_XENTR
320
0
36491
TrEMBL
Mitochondrion (Reliability: 3)
A0A6I8RBT7_XENTR
478
0
53774
TrEMBL
other Location (Reliability: 4)
F7EIM1_XENTR
368
0
40747
TrEMBL
other Location (Reliability: 2)
A4IHV9_XENTR
383
0
42733
TrEMBL
other Location (Reliability: 2)
F6UA27_XENTR
975
0
110470
TrEMBL
Mitochondrion (Reliability: 5)
A0A8J0SGD3_XENTR
977
0
109831
TrEMBL
other Location (Reliability: 3)
A0A6I8R7G4_XENTR
322
0
36597
TrEMBL
Secretory Pathway (Reliability: 1)
Q0VFM1_XENTR
378
0
41960
TrEMBL
other Location (Reliability: 2)
A0A6I8Q7W7_XENTR
195
0
21823
TrEMBL
other Location (Reliability: 1)
A0A8J0SUC1_XENTR
162
0
18668
TrEMBL
Mitochondrion (Reliability: 2)
B7ZSS4_XENTR
184
0
20676
TrEMBL
other Location (Reliability: 2)
Q5FVA0_XENTR
164
0
18205
TrEMBL
other Location (Reliability: 3)
A0A6I8SAE3_XENTR
305
0
34960
TrEMBL
other Location (Reliability: 1)
F7B1B3_XENTR
937
0
105415
TrEMBL
other Location (Reliability: 3)
A0A6I8SNQ6_XENTR
603
0
68291
TrEMBL
Secretory Pathway (Reliability: 5)
B0JYX2_XENTR
187
0
21271
TrEMBL
other Location (Reliability: 2)
F7DS87_XENTR
585
0
66685
TrEMBL
other Location (Reliability: 5)
A2VCU9_XENTR
507
0
57789
TrEMBL
Mitochondrion (Reliability: 3)
A0A6I8Q7S6_XENTR
332
0
38352
TrEMBL
other Location (Reliability: 3)
F6YU78_XENTR
508
0
57852
TrEMBL
Secretory Pathway (Reliability: 5)
A0A1B8Y4N2_XENTR
672
0
77298
TrEMBL
other Location (Reliability: 1)
A0A6I8SQ89_XENTR
481
1
54578
TrEMBL
other Location (Reliability: 2)
F6YU88_XENTR
536
0
60627
TrEMBL
other Location (Reliability: 4)
A0A8J0R0X3_XENTR
1418
0
159099
TrEMBL
other Location (Reliability: 4)
F6WCJ4_XENTR
276
0
31200
TrEMBL
other Location (Reliability: 1)
A0A803JIX9_XENTR
265
0
30073
TrEMBL
other Location (Reliability: 1)
Q28EB3_XENTR
367
0
41329
TrEMBL
other Location (Reliability: 2)
A0A6I8RJB4_XENTR
518
0
58312
TrEMBL
other Location (Reliability: 4)
A0A6I8R3J3_XENTR
513
0
58311
TrEMBL
other Location (Reliability: 4)
A0A6I8R642_XENTR
512
0
58410
TrEMBL
other Location (Reliability: 5)
A0A6I8Q9Y7_XENTR
250
0
28416
TrEMBL
Mitochondrion (Reliability: 4)
Q6P1U8_XENTR
589
0
65384
TrEMBL
other Location (Reliability: 2)
A0A803J2E2_XENTR
540
0
61295
TrEMBL
other Location (Reliability: 5)
A0A8J0SHC4_XENTR
491
0
56047
TrEMBL
other Location (Reliability: 2)
Q28BZ4_XENTR
221
0
25634
TrEMBL
other Location (Reliability: 1)