Reference on EC 3.1.21.5 - type III site-specific deoxyribonuclease
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Roberts, R.J.
Restriction enzymes and their isoschizomers
Nucleic Acids Res.
18
2331-2365
1990
Escherichia coli, Haemophilus influenzae, Salmonella enterica subsp. enterica serovar Typhi
Roberts, R.J.
Restriction and modification enzymes and their recognition sequences
Nucleic Acids Res.
11
r135-r167
1983
Escherichia coli
Roberts, R.J.; Macelis, D.
REBASE - restriction enzymes and methylases
Nucleic Acids Res.
29
268-269
2001
Escherichia coli
Kruger, D.H.; Kupper, D.; Meisel, A.; Tierlich, M.; Reuter, M.; Schroeder, C.
Restriction endonucleases functionally interacting with two DNA sites
Gene
157
165
1995
Escherichia coli
Gorbalenya, A.E.; Koonin, E.V.
Endonuclease (R) subunit of type-I and type-III restriction-modification enzymes contain a helicase-like domain
FEBS Lett.
291
277-281
1991
Escherichia coli
Kunz, A.; Mackeldanz, P.; Mucke, M.; Meisel, A.; Reuter, M.; Schroeder, C.; Kruger, D.H.
Mutual activation of two restriction endonucleases: interaction of EcoP1 and EcoP15
Biol. Chem.
379
617-620
1998
Escherichia coli
Su, P.; Im, H.; Hsieh, H.; Kang'a, S.; Dunn, N.W.
LlaFI, a type III restriction and modification system in Lactococcus lactis
Appl. Environ. Microbiol.
65
686-693
1999
BRENDA: Lactococcus lactis
Textmining: Bacteria, Firmicutes
Meisel, A.; Bickle, T.A.; Kruger, T.A.; Kruger, D.H.; Schroeder, C.
Type III restriction enzymes need two inversely oriented recognition sites for DNA cleavage
Nature
355
467-469
1992
Escherichia coli
Meisel, A.; Mackeldanz, P.; Bickle, T.A.; Kruger, D.H.; Schroeder, C.
Type III restriction endonucleases translocate DNA in a reaction driven by recognition site-specific ATP hydrolysis
EMBO J.
14
2958-2966
1995
Escherichia coli
Saha, S.; Rao, D.N.
Mutations in the Res subunit of the EcoPI restriction enzyme that affect ATP-dependent reactions
J. Mol. Biol.
269
342-354
1997
Escherichia coli
Hegna, I.K.; Bratland, H.; Kolsto, A.B.
BceS1, a new addition to the type III restriction and modification family
FEMS Microbiol. Lett.
202
189-193
2001
Bacillus cereus (P25241)
Janscak, P.; Sandmeier, U.; Szczelkun, M.D.; Bickle, T.A.
Subunit assembly and mode of DNA cleavage of the type III restriction endonucleases EcoP1I and EcoP15I
J. Mol. Biol.
306
417-431
2001
Escherichia coli, prophage P1
Bist, P.; Sistla, S.; Krishnamurthy, V.; Acharya, A.; Chandrakala, B.; Rao, D.N.
S-adenosyl-L-methionine is required for DNA cleavage by type III restriction enzymes
J. Mol. Biol.
310
93-109
2001
Escherichia coli
Mucke, M.; Reich, S.; Moncke-Buchner, E.; Reuter, M.; Kruger, D.H.
DNA cleavage by type III restriction-modification enzyme EcoP15I is independent of spacer distance between two head to head oriented recognition sites
J. Mol. Biol.
312
687-698
2001
Escherichia coli
Peakman, L.J.; Antognozzi, M.; Bickle, T.A.; Janscak, P.; Szczelkun, M.D.
S-adenosyl methionine prevents promiscuous DNA cleavage by the EcoP1I type III restriction enzyme
J. Mol. Biol.
333
321-335
2003
BRENDA: prophage P1
Textmining: DNA molecule
Reich, S.; Gossl, I.; Reuter, M.; Rabe, J.P.; Kruger, D.H.
Scanning force microscopy of DNA translocation by the type III restriction enzyme EcoP15I
J. Mol. Biol.
341
337-343
2004
BRENDA: Escherichia coli
Textmining: DNA molecule
Dryden, D.T.; Murray, N.E.; Rao, D.N.
Nucleoside triphosphate-dependent restriction enzymes
Nucleic Acids Res.
29
3728-3741
2001
Escherichia coli
Handa, N.; Kobayashi, I.
Type III restriction is alleviated by bacteriophage (RecE) homologous recombination function but enhanced by bacterial (RecBCD) function
J. Bacteriol.
187
7362-7373
2005
BRENDA: Escherichia coli
Textmining: Bacteriophage sp.
Mncke-Buchner, E.; Mackeldanz, P.; Kruger, D.H.; Reuter, M.
Overexpression and affinity chromatography purification of the Type III restriction endonuclease EcoP15I for use in transcriptome analysis
J. Biotechnol.
114
99-106
2004
Escherichia coli
Peakman, L.J.; Szczelkun, M.D.
DNA communications by Type III restriction endonucleases--confirmation of 1D translocation over 3D looping
Nucleic Acids Res.
32
4166-4174
2004
BRENDA: Escherichia coli
Textmining: plasmids, Transposon Tn21
Raghavendra, N.K.; Rao, D.N.
Unidirectional translocation from recognition site and a necessary interaction with DNA end for cleavage by Type III restriction enzyme
Nucleic Acids Res.
32
5703-5711
2004
Escherichia coli
Sears, A.; Szczelkun, M.D.
Subunit assembly modulates the activities of the Type III restriction-modification enzyme PstII in vitro
Nucleic Acids Res.
33
4788-4796
2005
Providencia stuartii, Providencia stuartii 164
Crampton, N.; Roes, S.; Dryden, D.T.; Rao, D.N.; Edwardson, J.M.; Henderson, R.M.
DNA looping and translocation provide an optimal cleavage mechanism for the type III restriction enzymes
EMBO J.
26
3815-3825
2007
Escherichia coli, Escherichia coli P15I
Wagenfuehr, K.; Pieper, S.; Mackeldanz, P.; Linscheid, M.; Krueger, D.H.; Reuter, M.
Structural domains in the type III restriction endonuclease EcoP15I: characterization by limited proteolysis, mass spectrometry and insertional mutagenesis
J. Mol. Biol.
366
93-102
2007
BRENDA: Escherichia coli
Textmining: insertion sequences
Fox, K.L.; Dowideit, S.J.; Erwin, A.L.; Srikhanta, Y.N.; Smith, A.L.; Jennings, M.P.
Haemophilus influenzae phasevarions have evolved from type III DNA restriction systems into epigenetic regulators of gene expression
Nucleic Acids Res.
35
5242-5252
2007
BRENDA: Haemophilus influenzae
Textmining: Bacteria, plasmids, Transformation
Crampton, N.; Yokokawa, M.; Dryden, D.T.; Edwardson, J.M.; Rao, D.N.; Takeyasu, K.; Yoshimura, S.H.; Henderson, R.M.
Fast-scan atomic force microscopy reveals that the type III restriction enzyme EcoP15I is capable of DNA translocation and looping
Proc. Natl. Acad. Sci. USA
104
12755-12760
2007
Escherichia coli
Neely, R.K.; Roberts, R.J.
The BsaHI restriction-modification system: cloning, sequencing and analysis of conserved motifs
BMC Mol. Biol.
9
48
2008
Geobacillus stearothermophilus (B0LX59)
Moencke-Buchner, E.; Rothenberg, M.; Reich, S.; Wagenfuehr, K.; Matsumura, H.; Terauchi, R.; Krueger, D.H.; Reuter, M.
Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target
J. Mol. Biol.
387
1309-1319
2009
Escherichia coli
Carpenter, M.A.; Bhagwat, A.S.
DNA base flipping by both members of the PspGI restriction-modification system
Nucleic Acids Res.
36
5417-5425
2008
Pyrococcus sp. GI-H
Ramanathan, S.P.; van Aelst, K.; Sears, A.; Peakman, L.J.; Diffin, F.M.; Szczelkun, M.D.; Seidel, R.
Type III restriction enzymes communicate in 1D without looping between their target sites
Proc. Natl. Acad. Sci. USA
106
1748-1753
2009
Escherichia coli
Adamczyk-Poplawska, M.; Lower, M.; Piekarowicz, A.
Characterization of the NgoAXP: phase-variable type III restriction-modification system in Neisseria gonorrhoeae
FEMS Microbiol. Lett.
300
25-35
2009
BRENDA: Neisseria gonorrhoeae (Q5F957), Neisseria gonorrhoeae
Textmining: Escherichia coli, Escherichia virus Lambda
Schwarz, F.W.; van Aelst, K.; Toth, J.; Seidel, R.; Szczelkun, M.D.
DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion
Nucleic Acids Res.
39
8042-8051
2011
Escherichia coli
Corvaglia, A.R.; Francois, P.; Hernandez, D.; Perron, K.; Linder, P.; Schrenzel, J.
A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strains
Proc. Natl. Acad. Sci. USA
107
11954-11958
2010
BRENDA: Escherichia coli, Staphylococcus aureus
Textmining: Transformation
Van Aelst, K.; Toth, J.; Ramanathan, S.; Schwarz, F.; Seidel, R.; Szczelkun, M.
Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat
Proc. Natl. Acad. Sci. USA
107
9123-9128
2010
Escherichia coli
Banerjee, A.; Rao, D.N.
Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695
PLoS ONE
6
e16810
2011
Helicobacter pylori 26695
Gupta, Y.K.; Yang, L.; Chan, S.H.; Samuelson, J.C.; Xu, S.Y.; Aggarwal, A.K.
Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering
J. Mol. Biol.
420
261-268
2012
Escherichia coli
Toth, J.; van Aelst, K.; Salmons, H.; Szczelkun, M.D.
Dissociation from DNA of Type III Restriction-Modification enzymes during helicase-dependent motion and following endonuclease activity
Nucleic Acids Res.
40
6752-6764
2012
Escherichia coli
Rao, D.N.; Dryden, D.T.; Bheemanaik, S.
Type III restriction-modification enzymes: a historical perspective
Nucleic Acids Res.
42
45-55
2014
Bacillus cereus, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Lactococcus lactis, Mannheimia haemolytica, Neisseria gonorrhoeae, Providencia stuartii, Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli 15T-
Butterer, A.; Pernstich, C.; Smith, R.M.; Sobott, F.; Szczelkun, M.D.; Toth, J.
Type III restriction endonucleases are heterotrimeric: comprising one helicase-nuclease subunit and a dimeric methyltransferase that binds only one specific DNA
Nucleic Acids Res.
42
5139-5150
2014
Escherichia coli, Providencia stuartii
Algire, M.A.; Montague, M.G.; Vashee, S.; Lartigue, C.; Merryman, C.
A type III restriction-modification system in Mycoplasma mycoides subsp. capri
Open Biology
2
120115
2012
BRENDA: Mycoplasma mycoides subsp. capri, Mycoplasma mycoides subsp. capri GM12
Textmining: Mycoplasma mycoides
Schwarz, F.W.; Toth, J.; van Aelst, K.; Cui, G.; Clausing, S.; Szczelkun, M.D.; Seidel, R.
The helicase-like domains of type III restriction enzymes trigger long-range diffusion along DNA
Science
340
353-356
2013
Escherichia coli
Toth, J.; Bollins, J.; Szczelkun, M.D.
Re-evaluating the kinetics of ATP hydrolysis during initiation of DNA sliding by Type III restriction enzymes
Nucleic Acids Res.
43
10870-10881
2015
Punavirus P1 (P08764), Escherichia coli (P12364)
Anjum, A.; Brathwaite, K.J.; Aidley, J.; Connerton, P.L.; Cummings, N.J.; Parkhill, J.; Connerton, I.; Bayliss, C.D.
Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168
Nucleic Acids Res.
44
4581-4594
2016
Campylobacter jejuni (Q0PC94), Campylobacter jejuni NCTC 11168 (Q0PC94)
Ahmad, I.; Kulkarni, M.; Gopinath, A.; Saikrishnan, K.
Single-site DNA cleavage by Type III restriction endonuclease requires a site-bound enzyme and a trans-acting enzyme that are ATPase-activated
Nucleic Acids Res.
46
6229-6237
2018
Escherichia coli (Q5ZND2)
De Backer, O; Colson, C
Two-step cloning and expression in Escherichia coli of the DNA restriction-modification system StyLTI of Salmonella typhimurium.
J Bacteriol
173
1321-7
1991
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia virus Lambda, Transformation
De Backer, O; Colson, C
Transfer of the genes for the StyLTI restriction-modification system of Salmonella typhimurium to strains lacking modification ability results in death of the recipient cells and degradation of their DNA.
J Bacteriol
173
1328-30
1991
Salmonella enterica subsp. enterica serovar Typhimurium
Davison, J; Brunel, F
Restriction insensitivity in bacteriophage T5 I. Genetic characterization of mutants sensitive to EcoRI restriction.
J Virol
29
11-6
1979
Escherichia virus T5, Escherichia coli
Piekarowicz, A; Brzeziński, R
Cleavage and methylation of DNA by the restriction endonuclease HinfIII isolated from Haemophilus influenzae Rf.
J Mol Biol
144
415-29
1980
Haemophilus influenzae
Steingrube, VA; Brown, BA; Gibson, JL; Wilson, RW; Brown, J; Blacklock, Z; Jost, K; Locke, S; Ulrich, RF; Wallace, RJ
DNA amplification and restriction endonuclease analysis for differentiation of 12 species and taxa of Nocardia, including recognition of four new taxa within the Nocardia asteroides complex.
J Clin Microbiol
33
3096-101
1995
Nocardia asteroides, Nocardia transvalensis, Nasa carnea
Rao, DN; Page, MG; Bickle, TA
Cloning, over-expression and the catalytic properties of the EcoP15 modification methylase from Escherichia coli.
J Mol Biol
209
599-606
1989
Escherichia coli
Rao, DN; Eberle, H; Bickle, TA
Characterization of mutations of the bacteriophage P1 mod gene encoding the recognition subunit of the EcoP1 restriction and modification system.
J Bacteriol
171
2347-52
1989
Escherichia virus P1
Schroeder, C; Jurkschat, H; Meisel, A; Reich, JG; Krüger, D
Unusual occurrence of EcoP1 and EcoP15 recognition sites and counterselection of type II methylation and restriction sequences in bacteriophage T7 DNA.
Gene
45
77-86
1986
Escherichia phage T7, Escherichia coli
Dartois, V; De Backer, O; Colson, C
Sequence of the Salmonella typhimurium StyLT1 restriction-modification genes: homologies with EcoP1 and EcoP15 type-III R-M systems and presence of helicase domains.
Gene
127
105-10
1993
Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli, Bacillus cereus
Ryan, KA; Lo, RY
Characterization of a CACAG pentanucleotide repeat in Pasteurella haemolytica and its possible role in modulation of a novel type III restriction-modification system.
Nucleic Acids Res
27
1505-11
1999
Mannheimia haemolytica, Escherichia coli, plasmids, Bibersteinia trehalosi
de Vries, N; Duinsbergen, D; Kuipers, EJ; Pot, RG; Wiesenekker, P; Penn, CW; van Vliet, AH; Vandenbroucke-Grauls, CM; Kusters, JG
Transcriptional phase variation of a type III restriction-modification system in Helicobacter pylori.
J Bacteriol
184
6615-23
2002
Helicobacter pylori
Sears, A; Peakman, LJ; Wilson, GG; Szczelkun, MD
Characterization of the Type III restriction endonuclease PstII from Providencia stuartii.
Nucleic Acids Res
33
4775-87
2005
Providencia stuartii
Bayliss, CD; Callaghan, MJ; Moxon, ER
High allelic diversity in the methyltransferase gene of a phase variable type III restriction-modification system has implications for the fitness of Haemophilus influenzae.
Nucleic Acids Res
34
4046-59
2006
Haemophilus influenzae, Bacteria, Bacteriophage sp.
Nakajima, T; Ono, K; Tazumi, A; Misawa, N; Moore, JE; Millar, BC; Matsuda, M
Molecular characterisation of a type III restriction-modification system in Campylobacter upsaliensis.
Br J Biomed Sci
71
66-72
2014
Campylobacter upsaliensis, Campylobacter upsaliensis RM3195, Terminator
Sears, A; Peakman, LJ; Wilson, GG; Szczelkun, MD
Characterization of the Type III restriction endonuclease PstII from Providencia stuartii.
Nucleic Acids Res
47
11477-11479
2019
Providencia stuartii
Toothman, P
Restriction alleviation by bacteriophages lambda and lambda reverse.
J Virol
38
621-31
1981
Bacteriophage sp., Escherichia coli, Escherichia virus Lambda
Xu, SY; Nugent, RL; Kasamkattil, J; Fomenkov, A; Gupta, Y; Aggarwal, A; Wang, X; Li, Z; Zheng, Y; Morgan, R
Characterization of type II and III restriction-modification systems from Bacillus cereus strains ATCC 10987 and ATCC 14579.
J Bacteriol
194
49-60
2012
Bacillus cereus, Bacteria, Bacillus anthracis, Bacillus thuringiensis, Archaea
Delver, EP; Kotova, VU; Zavilgelsky, GB; Belogurov, AA
Nucleotide sequence of the gene (ard) encoding the antirestriction protein of plasmid colIb-P9.
J Bacteriol
173
5887-92
1991
Escherichia coli
Belogurov, AA; Yussifov, TN; Kotova, VU; Zavilgelsky, GB
The novel gene(s) ARD of plasmid pKM101: alleviation of EcoK restriction.
Mol Gen Genet
198
509-13
1985
Escherichia virus Lambda
Zabeau, M; Friedman, S; Van Montagu, M; Schell, J
The ral gene of phage lambda. I. Identification of a non-essential gene that modulates restriction and modification in E. coli.
Mol Gen Genet
179
63-73
1980
Escherichia coli
Hadi, SM; Bächi, B; Iida, S; Bickle, TA
DNA restriction--modification enzymes of phage P1 and plasmid p15B. Subunit functions and structural homologies.
J Mol Biol
165
19-34
1983
Bacteria, plasmids, Escherichia virus P1
Qasem, JA; Khan, ZU; Mustafa, AS; Chugh, TD
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis and plasmid profile of soil and clinical isolates of Nocardia.
Microbiol Res
154
157-65
1999
Nocardia, Nocardia asteroides
Li, X; Ji, BX; Zhu, DL; Geng, ZC; Chu, RY
[Studies of the association of pathological myopia in Chinese patients with HLA alleles]
Yi Chuan Xue Bao
27
189-94
2000
Homo sapiens
Lorentzon, M; Lorentzon, R; Lerner, UH; Nordström, P
Calcium sensing receptor gene polymorphism, circulating calcium concentrations and bone mineral density in healthy adolescent girls.
Eur J Endocrinol
144
257-61
2001
Homo sapiens
Yakubu, A; Salako, AE; De Donato, M; Peters, SO; Takeet, MI; Wheto, M; Okpeku, M; Imumorin, IG
Association of SNP variants of MHC Class II DRB gene with thermo-physiological traits in tropical goats.
Trop Anim Health Prod
49
323-336
2017
Capra hircus
Nakajima T;Matsubara K;Ueno H;Kagawa S;Moore JE;Millar BC;Matsuda M
Molecular identification and characterization of type III restriction-modification (R-M) gene cluster in Campylobacter lari
Annals of microbiology
63
1629-1637
2013
Campylobacter lari
De Backer, O; Colson, C
Identification of the recognition sequence for the M.StyLTI methyltransferase of Salmonella typhimurium LT7: an asymmetric site typical of type-III enzymes.
Gene
97
103-7
1991
Salmonella typhimurium LT7, Escherichia coli
Sharrocks, AD; Hornby, DP
Transcriptional analysis of the restriction and modification genes of bacteriophage P1.
Mol Microbiol
5
685-94
1991
Escherichia virus P1
Moffatt, BA; Studier, FW
Entry of bacteriophage T7 DNA into the cell and escape from host restriction.
J Bacteriol
170
2095-105
1988
Escherichia phage T7
Iida, S; Meyer, J; Bächi, B; Stålhammar-Carlemalm, M; Schrickel, S; Bickle, TA; Arber, W
DNA restriction--modification genes of phage P1 and plasmid p15B. Structure and in vitro transcription.
J Mol Biol
165
1-18
1983
Escherichia virus P1, transposons
Burova, LM; Tovkach, FI
[Expression of genes of prophage P1 Escherichia coli in cells of phytopathogenic Erwinia]
Mikrobiol Z
68
39-47
0
Erwinia
Qian, BZ; Sugiyama, H; Waikagul, J; Zhu, ZH
[Sequence analysis of ITS2 and CO1 genes of Paragonimus harinasutai]
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
24
119-21
2006
Sinopotamon
Yu, D; Pi, B; Chen, Y; Wang, Y; Ruan, Z; Otto, M; Yu, Y
Characterization of the staphylococcal cassette chromosome composite island of Staphylococcus haemolyticus SH32, a methicillin-resistant clinical isolate from China.
PLoS One
9
e87346
2014
Staphylococcus haemolyticus
Krüger, DH; Kupper, D; Meisel, A; Reuter, M; Schroeder, C
The significance of distance and orientation of restriction endonuclease recognition sites in viral DNA genomes.
FEMS Microbiol Rev
17
177-84
1995
Viruses, Enterobacteria phage T3, DNA molecule
Saha, S; Rao, DN
ATP hydrolysis is required for DNA cleavage by EcoPI restriction enzyme.
J Mol Biol
247
559-67
1995
Escherichia virus P1
Hornby, DP; Müller, M; Bickle, TA
High level expression of the EcoP1 modification methylase gene and characterisation of the gene product.
Gene
54
239-45
1987
Escherichia virus Lambda
Hümbelin, M; Suri, B; Rao, DN; Hornby, DP; Eberle, H; Pripfl, T; Kenel, S; Bickle, TA
Type III DNA restriction and modification systems EcoP1 and EcoP15. Nucleotide sequence of the EcoP1 operon, the EcoP15 mod gene and some EcoP1 mod mutants.
J Mol Biol
200
23-9
1988
Escherichia virus P1
Ahmad, I; Rao, DN
Photolabeling of the EcoP15 DNA methyltransferase with S-adenosyl-L-methionine.
Gene
142
67-71
1994
Staphylococcus aureus
Sistla, S; Krishnamurthy, V; Rao, DN
Single-stranded DNA binding and methylation by EcoP1I DNA methyltransferase.
Biochem Biophys Res Commun
314
159-65
2004
Escherichia coli
Cherry, JL
Extreme C-to-A Hypermutation at a Site of Cytosine-N4 Methylation.
mBio
12
2021
Salmonella enterica
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