Reference on EC 3.1.21.2 - deoxyribonuclease IV
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sadowski, P.D.; Hurwitz, J.
Enzymatic breakage of deoxyribonucleic acid. II. Purification and properties of endonuclease IV from T4 phage-infected Escherichia coli
J. Biol. Chem.
244
6192-6198
1969
Escherichia coli, Escherichia coli B / ATCC 11303
Friedberg, E.C.; Hadi, S.M.; Goldthwait, D.A.
Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid
J. Biol. Chem.
244
5879-5889
1969
Escherichia coli
Carlson, K.; Lagerback, P.; Nystrom, A.C.
Bacteriophage T4 endonuclease II: concerted single-strand nicks yield double-strand cleavage
Mol. Microbiol.
52
1403-1411
2004
Tequatrovirus T4
Souza, L.L.; Eduardo, I.R.; Padula, M.; Leitao, A.C.
Endonuclease IV and exonuclease III are involved in the repair and mutagenesis of DNA lesions induced by UVB in Escherichia coli
Mutagenesis
21
125-130
2006
Escherichia coli (P0A6C1), Escherichia coli
Hirano, N.; Ohshima, H.; Takahashi, H.
Biochemical analysis of the substrate specificity and sequence preference of endonuclease IV from bacteriophage T4, a dC-specific endonuclease implicated in restriction of dC-substituted T4 DNA synthesis
Nucleic Acids Res.
34
4743-4751
2006
Tequatrovirus T4
Ohshima, H.; Hirano, N.; Takahashi, H.
A hexanucleotide sequence (dC1-dC6 tract) restricts the dC-specific cleavage of single-stranded DNA by endonuclease IV of bacteriophage T4
Nucleic Acids Res.
35
6681-6689
2007
Tequatrovirus T4
Hirano, N.; Ohshima, H.; Sakashita, H.; Takahashi, H.
The Ser176 of T4 endonuclease IV is crucial for the restricted and polarized dC-specific cleavage of single-stranded DNA implicated in restriction of dC-containing DNA in host Escherichia coli
Nucleic Acids Res.
35
6692-6700
2007
Tequatrovirus T4
Ivanov, I.; Tainer, J.A.; McCammon, J.A.
Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV
Proc. Natl. Acad. Sci. USA
104
1465-1470
2007
Escherichia coli (P0A6C1)
Back, J.H.; Chung, J.H.; Park, J.H.; Han, Y.S.
A versatile endonuclease IV from Thermus thermophilus has uracil-excising and 3-5 exonuclease activity
Biochem. Biophys. Res. Commun.
346
889-895
2006
Thermus thermophilus (Q72KH8), Thermus thermophilus
Hughes, R.C.; Tomanicek, S.J.; Ng, J.D.; Coates, L.
Purification, crystallization and preliminary crystallographic analysis of a thermostable endonuclease IV from Thermotoga maritima
Acta Crystallogr. Sect. F
65
1317-1319
2009
Thermotoga maritima (Q9WYJ7), Thermotoga maritima, Thermotoga maritima MSB8 / DSM 3109 / ATCC 43589 (Q9WYJ7)
Motta, E.S.; Souza-Santos, P.T.; Cassiano, T.R.; Dantas, F.J.; Caldeira-de-Araujo, A.; De Mattos, J.C.
Endonuclease IV is the main base excision repair enzyme involved in DNA damage induced by UVA radiation and stannous chloride
J. Biomed. Biotechnol.
2010
376218
2010
Escherichia coli, Escherichia coli AB1157
Andersson, C.E.; Lagerbaeck, P.; Carlson, K.
Structure of bacteriophage T4 endonuclease II mutant E118A, a tetrameric GIY-YIG enzyme
J. Mol. Biol.
397
1003-1016
2010
Tequatrovirus T4
Golan, G.; Ishchenko, A.; Khassenov, B.; Shoham, G.; Saparbaev, M.
Coupling of the nucleotide incision and 3'-5' exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences
Mutat. Res.
685
70-79
2010
Escherichia coli, Escherichia coli AB1157
Liu, G.; Ou, H.; Wang, T.; Li, L.; Tan, H.; Zhou, X.; Rajakumar, K.; Deng, Z.; He, X.
Cleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA
PLoS Genet.
6
1-13
2010
Streptomyces coelicolor, Streptomyces coelicolor A(3)2
Xie, J.J.; Liu, X.P.; Han, Z.; Yuan, H.; Wang, Y.; Hou, J.L.; Liu, J.H.
Chlamydophila pneumoniae endonuclease IV prefers to remove mismatched 3 ribonucleotides: implication in proofreading mismatched 3-terminal nucleotides in short-patch repair synthesis
DNA Repair
12
140-147
2013
Chlamydia pneumoniae
Tsutakawa, S.E.; Shin, D.S.; Mol, C.D.; Izumi, T.; Arvai, A.S.; Mantha, A.K.; Szczesny, B.; Ivanov, I.N.; Hosfield, D.J.; Maiti, B.; Pique, M.E.; Frankel, K.A.; Hitomi, K.; Cunningham, R.P.; Mitra, S.; Tainer, J.A.
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes
J. Biol. Chem.
288
8445-8455
2013
Thermotoga maritima (Q9WYJ7), Thermotoga maritima DSM 3109 (Q9WYJ7)
Puri, R.V.; Singh, N.; Gupta, R.K.; Tyagi, A.K.
Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage
PLoS ONE
8
e71535
2013
Mycobacterium tuberculosis (P9WQ13), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQ13)
Haas, B.; Sandigursky, M.; Tainer, J.; Franklin, W.; Cunningham, R.
Purification and characterization of Thermotoga maritima endonuclease IV, a thermostable apurinic/apyrimidinic endonuclease and 3-repair diesterase
J. Bacteriol.
181
2834-2839
1999
Thermotoga maritima (Q9WYJ7), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WYJ7)
Kong, X.J.; Wu, S.; Cen, Y.; Chen, T.T.; Yu, R.Q.; Chu, X.
Endonuclease IV cleaves apurinic/apyrimidinic sites in single-stranded DNA and its application for biosensing
Analyst
141
4373-4380
2016
Homo sapiens
Zhang, W.; Xu, Y.; Yan, M.; Li, S.; Wang, H.; Yang, H.; Zhou, W.; Rao, Z.
Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis
Biochem. Biophys. Res. Commun.
498
111-118
2018
Mycobacterium tuberculosis (P9WQ13), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQ13)
Abeldenov, S.; Talhaoui, I.; Zharkov, D.O.; Ishchenko, A.A.; Ramanculov, E.; Saparbaev, M.; Khassenov, B.
Characterization of DNA substrate specificities of apurinic/apyrimidinic endonucleases from Mycobacterium tuberculosis
DNA Repair
33
1-16
2015
Mycobacterium tuberculosis (P96273), Mycobacterium tuberculosis (P9WQ13), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P96273), Mycobacterium tuberculosis H37Rv (P9WQ13)
html completed
