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Information on EC 3.1.1.93 - mycophenolic acid acyl-glucuronide esterase and Organism(s) Bos taurus

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.93 mycophenolic acid acyl-glucuronide esterase
IUBMB Comments
This liver enzyme deglucuronidates mycophenolic acid O-acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate that is thought to be immunotoxic.
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Bos taurus
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Word Map
The taxonomic range for the selected organisms is: Bos taurus
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
abhd10, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
AcMPAG deglucuronidase
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mycophenolic acid acyl-glucuronide deglucuronidase
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SYSTEMATIC NAME
IUBMB Comments
mycophenolic acid O-acyl-glucuronide-ester hydrolase
This liver enzyme deglucuronidates mycophenolic acid O-acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate that is thought to be immunotoxic.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ABHDA_BOVIN
306
0
33983
Swiss-Prot
Mitochondrion (Reliability: 4)