We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments Acetoacetate and, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptors; malonyl-CoA can act instead of succinyl-CoA.
The taxonomic range for the selected organisms is: Mus musculus The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
coa transferase, oxct1, 3-oxoacid coa-transferase, succinyl-coa:3-ketoacid coa transferase, 3-ketoacid coa-transferase, succinyl-coa transferase, scot-t, succinyl-coa:3-oxoacid coa transferase, succinyl-coa:3-oxoacid coa-transferase, succinyl-coa:3-ketoacid coenzyme a transferase,
more
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-ketoacid CoA-transferase
-
-
-
-
3-ketoacid coenzyme A transferase
-
-
-
-
3-ketoacid coenzyme A-transferase
-
-
-
-
3-oxo-CoA transferase
-
-
-
-
3-oxoacid CoA dehydrogenase
-
-
-
-
3-oxoacid coenzyme A-transferase
-
-
-
-
acetoacetate succinyl-CoA transferase
-
-
-
-
acetoacetyl coenzyme A-succinic thiophorase
-
-
-
-
coenzyme A-transferase, 3-oxoacid
-
-
-
-
succinyl coenzyme A-acetoacetyl coenzyme A-transferase
-
-
-
-
succinyl-CoA transferase
-
-
-
-
succinyl-CoA:3-ketoacid coenzyme A transferase-1
-
succinyl-CoA:acetoacetate CoA transferase
-
-
-
-
testis-specific succinyl-CoA:3-oxo-acid CoA-transferase
-
-
-
-
SCOT
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
coenzyme A transfer
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
succinyl-CoA:3-oxo-acid CoA-transferase
Acetoacetate and, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptors; malonyl-CoA can act instead of succinyl-CoA.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
succinyl-CoA + acetoacetate
?
-
liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate
-
-
?
succinyl-CoA + acetoacetate
succinate + acetoacetyl-CoA
succinyl-CoA + acetoacetate
succinate + acetoacetyl-CoA
-
-
-
?
succinyl-CoA + acetoacetate
succinate + acetoacetyl-CoA
-
-
-
?
succinyl-CoA + acetoacetate
succinate + acetoacetyl-CoA
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
succinyl-CoA + acetoacetate
?
-
liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
9.24
calculated from nucleotide sequence
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
SwissProt
brenda
-
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
-
brenda
-
brenda
-
-
brenda
-
neuroblastoma N2a cell line
brenda
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SCO2A_MOUSE
520
0
56473
Swiss-Prot
Mitochondrion (Reliability: 1 )
SCO2B_MOUSE
520
0
56592
Swiss-Prot
Mitochondrion (Reliability: 1 )
SCOT1_MOUSE
520
0
55989
Swiss-Prot
Mitochondrion (Reliability: 1 )
Q3UK61_MOUSE
520
0
56017
TrEMBL
Mitochondrion (Reliability: 1 )
Q3UJQ9_MOUSE
486
0
52278
TrEMBL
Mitochondrion (Reliability: 1 )
Q3U9P7_MOUSE
520
0
56049
TrEMBL
Mitochondrion (Reliability: 1 )
A0A0R4J198_MOUSE
520
0
56546
TrEMBL
Mitochondrion (Reliability: 1 )
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
56530
calculated from nucleotide sequence
58000
x * 58000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
nitrosylation
diabetes is associated with a higher nitrosylation degree of tyrosine 76 and tyrosine374
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
degradation of 3-oxo acid CoA-transferase in glioma and neuroblastoma cells
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
the enzyme catalytic activity is significantly reduced in the hearts of diabetic wild type diabetic mice at weeks 4-12 postinduction, with the lowest level observed at week 4 postinduction
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Zammit, V.A.; Beis, A.; Newsholme, E.A.
The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver
FEBS Lett.
103
212-215
1979
Gallus gallus, Clupea harengus, Columba livia, Oryctolagus cuniculus, Dicentrarchus labrax, Lacerta viridis, Mus musculus, Oncorhynchus mykiss, Pleuronectes platessa, Raja clavata, Rattus norvegicus, Scomber scombrus, Scyliorhinus canicula
brenda
Haney, P.M.; Bolinger, L.; Raefsky, C.; Patel, M.S.
Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells
Biochem. J.
224
67-74
1984
Mus musculus, Rattus norvegicus
brenda
Koga, M.; Tanaka, H.; Yomogida, K.; Nozaki, M.; Tsuchida, J.; Ohta, H.; Nakamura, Y.; Masai, K.; Yoshimura, Y.; Yamanaka, M.; Iguchi, N.; Nojima, H.; Matsumiya, K.; Okuyama, A.; Nishimune, Y.
Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase
Biol. Reprod.
63
1601-1609
2000
Mus musculus, Mus musculus (Q9JJN4)
brenda
Cong, W.; Ma, W.; Zhao, T.; Zhu, Z.; Wang, Y.; Tan, Y.; Li, X.; Jin, L.; Cai, L.
Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374)
Am. J. Physiol. Endocrinol. Metab.
304
E826-E835
2013
Mus musculus (Q9D0K2)
brenda