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3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + deoxycorticosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + estradiol-17beta
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + testosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
additional information
?
-
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
no substrates are AMP, ADP, ATP or GTP
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
no substrates are AMP, ADP, ATP or GTP
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
requires 0.04 mM cortisol for maximal activity
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Meriones sp.
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Meriones sp.
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Meriones sp.
-
requires 0.5 mM cortisol for maximal activity
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
requires 0.5 mM cortisol for maximal activity
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
i.e. PAPS, glucocorticoids are preferred substrates
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
i.e. PAPS, glucocorticoids are preferred substrates
-
?
additional information
?
-
-
sulfotransferase I is not as specific as sulfotransferase III
-
-
?
additional information
?
-
-
involved in control of corticosteroid metabolism
-
-
?
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3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
additional information
?
-
-
involved in control of corticosteroid metabolism
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Meriones sp.
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Meriones sp.
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol 21-sulfate
-
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Ba2+
-
activation
Ba2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Ba2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Ba2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Ca2+
-
activation
Ca2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Ca2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Ca2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Co2+
-
activation
Co2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Co2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Co2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Cr2+
-
activation
Cr2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Cr2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Cr2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Fe3+
-
not
Fe3+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Fe3+
-
slight activation, 5 mM
Mg2+
-
activation
Mg2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Mg2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Mg2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Mn2+
-
activation
Mn2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Mn2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Mn2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Ni2+
-
activation
Ni2+
-
in decreasing order of efficiency: Cr2+, Mn2+, Co2+, Mg2+, Ni2+, Ca2+, Fe3+, Ba2+
Ni2+
-
in decreasing order of efficiency: Cr2+, Mg2+, Ba2+, Mn2+, Ni2+, Ca2+, Co2+
Ni2+
-
in decreasing order of efficiency: Mn2+, Cr2+, Co2+, Mg2+, Ba2+, Ca2+, Ni2+
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3'-phosphoadenylylsulfate
-
inhibition above 0.33 mM
adenosine 3',5'-bisphosphate
-
product inhibition
Antibodies to sulfotransferase III
-
sulfotransferase I
-
Cd2+
-
5 mM, strong inhibition
corticosterone
-
cortisol as substrate, strong
cortisol
-
inhibition above 0.08 mM
Cortisol 21-sulfate
-
product inhibition
cortisone
-
cortisol as substrate, weak, 0.012 mM
deoxycorticosterone
-
cortisol as substrate, strong
testosterone
-
cortisol as substrate, strong
Zn2+
-
5 mM, strong inhibition
additional information
-
no inhibition by adenine nucleotides
-
dehydroepiandrosterone
-
cortisol as substrate; kinetics
dehydroepiandrosterone
-
cortisol as substrate; strong
dexamethasone
-
cortisol as substrate; kinetics
dexamethasone
-
cortisol as substrate; weak
diethylstilbestrol
-
cortisol as substrate
diethylstilbestrol
-
cortisol as substrate; strong
estradiol-17beta
-
cortisol as substrate; strong
estradiol-17beta
-
44% inhibition at 0.012 mM; cortisol as substrate
progesterone
-
cortisol as substrate
progesterone
-
cortisol as substrate; strong
tetrahydrocortisol
-
cortisol as substrate
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Singer, S.S.; Gebhart, J.; Hess, E.
Enzymatic sulfation of steroids. V. Partial purification and some properties of sulfotransferase III, the major glucocorticoid sulfotransferase of liver cytosol from male rats
Can. J. Biochem.
56
1028-1035
1978
Rattus norvegicus
brenda
Singer, S.S.; Brill, B.
Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol
Biochim. Biophys. Acta
712
590-596
1982
Cavia porcellus, Rattus norvegicus, Cavia porcellus Hartley
brenda
Singer, S.S.
Partial purification and some properties of rat liver sulfotransferase I, a glucocorticoid sulfotransferase usually restricted to female rats
Arch. Biochem. Biophys.
196
340-349
1979
Rattus norvegicus
brenda
Singer, S.S.; Bruns, L.
Enzymatic sulfation of steroids. XI. The extensive purification and some properties of hepatic sulfotransferase III from female rats
Can. J. Biochem.
58
660-666
1980
Rattus norvegicus
brenda
Federspeil, M.J.; Singer, S.S.
Enzymatic sulfation of steroids. XIV. The glucocorticoid sulfotransferases of Bos Taurus liver
Comp. Biochem. Physiol. B
69
511-516
1981
Bos taurus, Rattus norvegicus
-
brenda
Singer, S.S.
Glucocorticoid sulphotransferases in rats and other animal species
Biochem. Soc. Trans.
12
35-39
1984
Bos taurus, Cavia porcellus, Gallus gallus, Meriones sp., Mesocricetus auratus, Rattus norvegicus
brenda
Singer, S.S.; Galaska, E.G.; Feeser, T.A.; Benak, R.L.; Ansel, A.Z.; Moloney, A.
Enzymic sulfation of steroids. XIX. Cortisol sulfotransferase activity, glucocorticoid sulfotransferases, and tyrosine aminotransferase induction in chicken, gerbil, and hamster liver
Can. J. Biochem. Cell Biol.
63
23-32
1985
Gallus gallus, Meriones sp., Mesocricetus auratus
brenda