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Information on EC 2.7.8.11 - CDP-diacylglycerol-inositol 3-phosphatidyltransferase and Organism(s) Danio rerio

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Danio rerio
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The taxonomic range for the selected organisms is: Danio rerio
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
phosphatidylinositol synthase, pi synthase, ptdins synthase, cdipt, zmpis, cdp-diglyceride:inositol transferase, cdp-dg:inositol transferase, pkpis, cdp-diacylglycerol-inositol 3-phosphatidyltransferase, bnptdins s1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
cdipt
-
-
CDP-DG:inositol transferase
-
-
-
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CDP-diacylglycerol-inositol 3-phosphatidyltransferase
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CDP-diacylglycerol-inositol phosphatidyltransferase
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-
-
-
CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase
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-
-
-
CDP-diglyceride-inositol phosphatidyltransferase
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-
-
-
CDP-diglyceride-inositol transferase
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-
-
-
CDP-diglyceride:inositol transferase
-
-
-
-
CDPdiglyceride-inositol phosphatidyltransferase
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-
-
-
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase
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-
-
-
cytidine diphosphodiglyceride-inositol phosphatidyltransferase
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-
-
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cytidine diphosphoglyceride-inositol phosphatidyltransferase
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-
-
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cytidine diphosphoglyceride-inositol transferase
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-
-
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phosphatidylinositol synthase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
substituted phospho group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -
SYSTEMATIC NAME
IUBMB Comments
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9027-01-4
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
using a cdipt knockout it shown that cdipt is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q6NYP5_DANRE
213
4
23979
TrEMBL
Secretory Pathway (Reliability: 2)
Q6DRN8_DANRE
213
4
23995
TrEMBL
Secretory Pathway (Reliability: 2)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
S111C
-
missense mutation leads to lens opaque (lop) phenotype. Mutation is located in the catalytic domain of the 213 amino acid phosphatidylinositol (PI) synthase enzyme
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Murphy, T.R.; Vihtelic, T.S.; Ile, K.E.; Watson, C.T.; Willer, G.B.; Gregg, R.G.; Bankaitis, V.A.; Hyde, D.R.
Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye
Exp. Eye Res.
93
460-474
2011
Danio rerio
Manually annotated by BRENDA team