Reference on EC 2.7.7.84 - 2'-5' oligoadenylate synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hartmann, R.; Justesen, J.; Sarkar, S.N.; Sen, G.C.; Yee, V.C.
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Mol. Cell
12
1173-1185
2003
Homo sapiens, Sus scrofa, Sus scrofa (Q29599)
Feng, Y.; Yang, K.
A comparative study of different types of rabbit 2',5'-oligoadenylate synthetase
Acta Biochim. Biophys. Sin. (Shanghai)
29
249-250
1997
Oryctolagus cuniculus
-
Ferbus, D.; Justesen, J.; Besancon, F.; Thang, M.
The 2'5' oligoadenylate synthetase has a multifunctional 2',5' nucleotidyl-transferase activity
Biochem. Biophys. Res. Commun.
100
847-856
1981
Gallus gallus, Oryctolagus cuniculus, Homo sapiens, Mus musculus
Hughes, B.; Srivastava, P.; Muse, D.; Robins, R.
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 1. Substrate specificity of the interferon-induced murine 2',5'-oligoadenylate synthetase and enzymatic synthesis of oligomers
Biochemistry
22
2116-2126
1983
Mus musculus
Suhadolnik, R.; Flick, M.; Mosca, J.; Sawada, Y.; Doetsch, P.; Vonderheid, E.
2',5'oligoadenylate synthetase from cutaneous T-cell lymphoma: biosynthesis, identification, quantitation, molecular size of the 2',5'oligoadenylates, and inhibition of protein synthesis
Biochemistry
22
4153-4158
1983
Homo sapiens
Hovanessian, A.; Justesen, J.
The human 2'-5' oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation
Biochimie
89
779-788
2007
Homo sapiens
Hartmann, R.; Walko, G.; Justesen, J.
Inhibition of 2'-5' oligoadenylate synthetase by divalent metal ions
FEBS Lett.
507
54-58
2001
Homo sapiens
Behera, A.; Kumar, M.; Lockey, R.; Mohapatra, S.
2'-5' oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells
J. Biol. Chem.
277
25601-25608
2002
Homo sapiens
Kajaste-Rudnitski, A.; Mashimo, T.; Frenkiel, M.; Guenet, J.; Lucas, M.; Despres, P.
The 2',5'oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells
J. Biol. Chem.
281
4624-4637
2006
Mus musculus
Meng, H.; Deo, S.; Xiong, S.; Dzananovic, E.; Donald, L.; Van Dijk, C.; McKenna, S.
Regulation of the interferon-inducible 2'-5'-oligoadenylate synthetases by adenovirus VAI RNA
J. Mol. Biol.
422
635-649
2012
Homo sapiens
Schroeder, H.; Natalio, F.; Wiens, M.; Tahir, M.; Shukoor, M.; Tremel, W.; Belikov, S.; Krasko, A.; Mueller, W.
The 2'-5'-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensis
Mol. Immunol.
45
945-953
2008
Lubomirskia baikalensis
Truve, E.; Aaspollu, A.; Honkanen, J.; Puska, R.; Mehto, M.; Hassi, A.; Teeri, T.; Kelve, M.; Seppaenen, P.; Saarma, M.
Transgenic potato plants expressing mammalian 2'-5' oligoadenylate synthetase are protected from potato virus X infection under field conditions
Nat. Biotechnol.
11
1048-1052
1993
Rattus norvegicus (Q05961)
Paeri, M.; Kuusksalu, A.; Lopp, A.; Kjaer, K.H.; Justesen, J.; Kelve, M.
Enzymatically active 2,5-oligoadenylate synthetases are widely distributed among Metazoa, including protostome lineage
Biochimie
97
200-209
2014
Tedania ignis (U5XFV4)
Bhosle, S.; Hunt, A.; Chaudhary, J.
A modified coupled spectrophotometric method to detect 2-5 oligoadenylate synthetase activity in prostate cell lines
Biol. Proced. Online
18
009
2016
Homo sapiens
Kwon, Y.; Kang, J.; Hwang, S.; Ahn, B.
The ribonuclease l-dependent antiviral roles of human 2',5'-oligoadenylate synthetase family members against hepatitis C virus
FEBS Lett.
587
156-164
2013
Homo sapiens (P00973)
Dar, A.A.; Pradhan, T.N.; Kulkarni, D.P.; Shah, S.U.; Rao, K.V.; Chaukar, D.A.; DCruz, A.K.; Chiplunkar, S.V.
Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 activation in oral cancer
Immunology
147
251-264
2016
Homo sapiens
Kot, L.; Kompanets, I.; Ostapchenko, L.; Bogdanova, O.
2,5-oligoadenylate-synthetase activity in lymphoid cells of rats with experimental stress-induced gastric ulcer
Russ. J. Biopharm.
7
14-20
2015
Rattus norvegicus
-
Zhao, J.; Feng, N.; Li, Z.; Wang, P.; Qi, Z.; Liang, W.; Zhou, X.; Xu, X.; Liu, B.
2',5'-Oligoadenylate synthetase 1 (OAS1) inhibits PRRSV replication in Marc-145 cells
Antiviral Res.
132
268-273
2016
Chlorocebus sabaeus (A0A0D9S3Y6)
Koul, A.; Deo, S.; Booy, E.P.; Orriss, G.L.; Genung, M.; McKenna, S.A.
Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthetase 2 (OAS2)
Biochem. Cell Biol.
98
70-82
2020
Homo sapiens (P00973), Homo sapiens (P29728), Homo sapiens
Gonzalez, K.J.; Moncada-Giraldo, D.M.; Gutierrez, J.B.
In silico identification of potential inhibitors against human 2'-5'-oligoadenylate synthetase (OAS) proteins
Comput. Biol. Chem.
85
107211
2020
Homo sapiens (P00973), Homo sapiens (P29728), Homo sapiens (Q9Y6K5)
Elkhateeb, E.; Tag-El-Din-Hassan, H.T.; Sasaki, N.; Torigoe, D.; Morimatsu, M.; Agui, T.
The role of mouse 2',5'-oligoadenylate synthetase 1 paralogs
Infect. Genet. Evol.
45
393-401
2016
Mus musculus (P11928), Mus musculus (Q14AZ4), Mus musculus (Q60856), Mus musculus (Q8C2W3), Mus musculus (Q8K469), Mus musculus (Q8VI95), Mus musculus (Q8VI97), Mus musculus (Q924S2), Mus musculus, Mus musculus C57BL/6J (B6) (P11928), Mus musculus C57BL/6J (B6) (Q14AZ4), Mus musculus C57BL/6J (B6) (Q60856), Mus musculus C57BL/6J (B6) (Q8C2W3), Mus musculus C57BL/6J (B6) (Q8K469), Mus musculus C57BL/6J (B6) (Q8VI95), Mus musculus C57BL/6J (B6) (Q8VI97), Mus musculus C57BL/6J (B6) (Q924S2)
Tag-El-Din-Hassan, H.T.; Morimatsu, M.; Agui, T.
Functional analysis of duck, goose, and ostrich 2'-5'-oligoadenylate synthetase
Infect. Genet. Evol.
62
220-232
2018
Struthio camelus australis (A0A093JNH5), Anser cygnoides (A0A1B1V537), Anas platyrhynchos (A0A1B1V538), Anas platyrhynchos, Gallus gallus (H9L0X6), Gallus gallus
Tag-El-Din-Hassan, H.T.; Sasaki, N.; Torigoe, D.; Morimatsu, M.; Agui, T.
Analysis of the relationship between enzymatic and antiviral activities of the chicken oligoadenylate synthetase-like
J. Interferon Cytokine Res.
37
71-80
2017
Gallus gallus (H9L0X6), Gallus gallus
Leisching, G.; Ali, A.; Cole, V.; Baker, B.
2'-5'-Oligoadenylate synthetase-like protein inhibits intracellular M. tuberculosis replication and promotes proinflammatory cytokine secretion
Mol. Immunol.
118
73-78
2020
Homo sapiens (Q15646)
Skrivergaard, S.; Jensen, M.S.; Rolander, T.B.; Nguyen, T.B.N.; Bundgaard, A.; Nejsum, L.N.; Martensen, P.M.
The cellular localization of the p42 and p46 oligoadenylate synthetase 1 isoforms and their impact on mitochondrial respiration
Viruses
11
1122
2019
Homo sapiens (P00973), Homo sapiens
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